Page last updated: 2024-11-06

thymidine and Microsatellite Instability

thymidine has been researched along with Microsatellite Instability in 2 studies

Microsatellite Instability: The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.

Research Excerpts

ExcerptRelevanceReference
"A panel of colon cancer cell lines was assayed for response to camptothecin-thymidine combinations by measuring colony formation, cell cycle distribution, and senescence."1.35Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11. ( Cox, A; Hansen, LT; Helleday, T; Meuth, M; Phear, G; Rodriguez, R; Scorah, J; Spang-Thomsen, M, 2008)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Floer, M1
Binion, DG1
Nelson, VM1
Manley, S1
Wellner, M1
Sadeghi, S1
Behmaram, B1
Sewell, C1
Otterson, MF1
Kucharzik, T1
Rafiee, P1
Rodriguez, R1
Hansen, LT1
Phear, G1
Scorah, J1
Spang-Thomsen, M1
Cox, A1
Helleday, T1
Meuth, M1

Other Studies

2 other studies available for thymidine and Microsatellite Instability

ArticleYear
Role of MutS homolog 2 (MSH2) in intestinal myofibroblast proliferation during Crohn's disease stricture formation.
    American journal of physiology. Gastrointestinal and liver physiology, 2008, Volume: 295, Issue:3

    Topics: Adult; Cell Proliferation; Cells, Cultured; Crohn Disease; DNA-Binding Proteins; Female; Fibroblasts

2008
Thymidine selectively enhances growth suppressive effects of camptothecin/irinotecan in MSI+ cells and tumors containing a mutation of MRE11.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Sep-01, Volume: 14, Issue:17

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Colonic Neo

2008