thymidine has been researched along with Metastase in 98 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 3,800 node-negative breast cancers recruited between 1972 and 1991, the consistency of information provided by the 3H-thymidine labelling index (TLI), in terms of basic relations with other clinico-pathological and biological variables and clinical predictivity, was evaluated using a combined analysis of results previously published by our group for distinct series of patients." | 5.30 | Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index. ( Daidone, MG; Leutner, M; Luisi, A; Mastore, M; Salvadori, B; Silvestrini, R, 1997) |
| "Proliferative activity, evaluated as [3H]thymidine labelling index ([3H]dT LI), and hormone receptors were determined on 97 primary breast cancers and on metachronous lesions from the same patient." | 3.68 | Biological characterisation of primary and metachronous lesions in breast cancer patients. ( Coradini, D; Daidone, MG; Di Fronzo, G; Salvadori, B; Silvestrini, R; Valentinis, B, 1992) |
| "The 3H-thymidine labeling index (LI) was determined on 178 lesions, four of which were primary, from 129 patients with malignant melanoma." | 3.67 | Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin. ( Attili, A; Clemente, C; Costa, A; Grignolio, E; Silvestrini, R; Testori, A, 1987) |
| "Proliferation kinetic parameters of 9 osteogenic sarcomas (6 primary tumours, 3 lung metastases) and 3 Ewing's sarcomas were determined using an autoradiographic in vitro method (single and double labelling with 3H- and 14C-thymidine, and 3H-uridine)." | 3.66 | Autoradiographic in vitro study of the cell kinetics of osteogenic sarcomas and Ewing's sarcomas in children. ( Willnow, U, 1982) |
| "The rate of cell proliferation of 99 bronchogenic carcinomas (94 primary tumors and 5 metastases) was evaluated from the labeling index after in vitro incorporation of [3H]thymidine; the rate was then correlated with the histologic tumor type according to the classification of the World Health Organization (WHO)." | 3.65 | Cell proliferation and histologic classification of bronchogenic carcinoma. ( Borgeskov, S; Dombernowsky, P; Hainau, B; Hansen, HH, 1977) |
| "Noncurative excision of a primary sc Lewis lung tumor performed on Day 7 or later results in an increase in the thymidine index and growth rate with minimal changes in the cell cycle parameters of the lung metastases." | 3.65 | Effects of surgery on the cell kinetics of residual tumor. ( Holmquist, JP; Simpson-Herren, L, 1976) |
| "Tritiated thymidine incorporation by peripheral human lymphocytes stimulated with phytohemagglutinin (PHA) was investigated in 18 colorectal carcinoma patients (seven with localized tumor and 11 with metastatic tumors)." | 3.65 | Phytohemagglutinin-stimulated immune response. Assay in colorectal carcinoma patients. ( Kaplan, MS; Kummerfeld, KB; Lundak, RL; Mino, FO, 1975) |
| "The in vitro effects of cortisol, estradiol, progesterone, and testosterone on the uptake of tritiated thymidine into the tumor cells of 25 women with primary or metastatic breast cancer were studied and compared with the objective clinical response to ablative endocrine surgery." | 3.65 | In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation. ( Burstein, NA; Carey, RW, 1974) |
| "TP is overexpressed in various tumors and plays an important role in angiogenesis, tumor growth, invasion and metastasis." | 2.42 | The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression. ( Akiyama, S; Furukawa, T; Haraguchi, M; Nakajima, Y; Shimaoka, S; Sumizawa, T; Takebayashi, Y, 2004) |
| "BRCA2 protein depletion after cancer cell adhesion to COL1 or in small RNA interference assays triggers new DNA synthesis, a trophic effect that is abrogated by recombinant BRCA2 expression." | 1.33 | Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation. ( Arbini, AA; Greco, M; Marra, E; Moro, L, 2005) |
| "In 3,800 node-negative breast cancers recruited between 1972 and 1991, the consistency of information provided by the 3H-thymidine labelling index (TLI), in terms of basic relations with other clinico-pathological and biological variables and clinical predictivity, was evaluated using a combined analysis of results previously published by our group for distinct series of patients." | 1.30 | Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index. ( Daidone, MG; Leutner, M; Luisi, A; Mastore, M; Salvadori, B; Silvestrini, R, 1997) |
| "The number of colonies of hepatic metastasis correlated well with the area under the curve of the distributed amount of the tumor cells in the liver, regardless of the injection route; the correlation line was identical for each injection route." | 1.30 | Importance of hepatic first-pass removal in metastasis of colon carcinoma cells. ( Irimura, T; Izumi, Y; Kato, Y; Mizuno, N; Sugiyama, Y, 1998) |
| "In 173 patients with operable gastric cancer, the relations between thymidine uptake by gastric cancer cells in semi-solid media and their clinicopathologic features as well as their survival lengths were studied." | 1.29 | Thymidine uptake in vitro as a prognostic indicator for primary gastric cancer. ( Fujii, H; Masuda, Y; Muraoka, R; Shimomatsuya, T; Tanaka, T; Tanigawa, N, 1993) |
| "Paradoxically, primary human breast carcinoma cells are difficult to establish in culture: most outgrowths arise from the normal tissue surrounding the tumor." | 1.28 | Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. ( Bissell, MJ; Howlett, AR; Petersen, OW; Rønnov-Jessen, L, 1992) |
| "Tumor sensitivity of ovarian cancer to cytotoxic drugs in vitro was examined between paired samples taken from the primary tumor and its metastases in the same patient." | 1.28 | In vitro sensitivity of ovarian cancer as determined by a short-term biochemical assay: comparison between primary and metastatic sites in the same patient. ( Hurst, T; Khoo, SK; Lark, J; Mackay, EV; Parsons, P; Webb, MJ, 1989) |
| "Why do malignant tumors initially grow rapidly, then more slowly? What accounts for the different rats of growth among different tumors? Can the answers to these and related questions enable us to improve the results of cancer therapy? With advanced technology, we have come a long way in penetrating the mechanisms of tumor cell kinetics, but to date clinical strategies have not kept pace." | 1.27 | Biology and tumor growth. ( Tannock, IF, 1983) |
| " Although the relationship among administered dose, tissue concentration, and therapeutic and/or toxic effects remains extremely complex, a series of experimental and clinical studies provides information on the pharmacokinetic behavior of most anticancer agents in different conditions." | 1.27 | Pharmacokinetic studies of anticancer drugs in tumor-bearing animals. ( D'Incalci, M; Donelli, MG; Garattini, S, 1984) |
| "The ability to form spontaneous metastasis (SM) in the lungs and in other organs appears among cell variants isolated at days 10 to 21 after inoculation." | 1.27 | Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity. ( Deichman, GI; Vendrov, EL, 1986) |
| "The analysis was performed on primary tumors and their synchronous metastases from 67 patients with breast, ovarian, gastrointestinal and germ cell testicular tumors." | 1.27 | Drug sensitivity of different tumor lesions from the same patient evaluated by a short-term assay. ( Bolis, G; Daidone, MG; Sanfilippo, O; Seminara, P; Silvestrini, R; Zaffaroni, N, 1988) |
| " In pharmacokinetic studies in five patients, both schedules produced prolonged plasma beta-half-lives of 5-FU (96-189 minutes)." | 1.27 | Phase I evaluation and pharmacokinetic study of weekly iv thymidine and 5-FU in patients with advanced colorectal carcinoma. ( Chun, H; Kemeny, N; Lynch, G; Martin, D; Young, C, 1985) |
| "The surgical specimens of breast tumors were incubated in vitro with tritiated thymidine and autoradiographies were performed." | 1.26 | Kinetic parameters and the course of the disease in breast cancer. ( Chavaudra, N; Contesso, G; Gioanni, J; Malaise, EP; Pejovic, MJ; Renaud, A; Tubiana, M, 1981) |
| "tumor, spontaneous metastases, and lung colonies formed after i." | 1.26 | Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma. ( Cuman, R; Giraldi, T; Lassiani, L; Nisi, C; Sava, G, 1981) |
| "1." | 1.26 | An approach to the problem of heterogeneity of human tumour-cell populations. ( Sirachý, J, 1979) |
| "Primary tumors and their metastases in regional lymph nodes show certain differences relative both to the rate of the process and intensity of the DNA synthesis, and relative number of cells with incorporated labelled thymidine." | 1.25 | [A kinetic analysis of the growth of transplanted tumors and their metastasis]. ( D'iachkovskaia, RF; Emanuel', NM; Kiseleva, EG; Konovalova, NP; Volkova, IM, 1975) |
| "Primary tumours and metastases of the same patient frequently showed different sensitivity." | 1.25 | [In-vitro testing of the sensitivity of mammary carcinoma cells to cytostatic drugs (author's transl)]. ( Bastert, G; Gerner, R; Leppien, G; Michel, RT; Nord, D; Schmidt-Matthiesen, H, 1975) |
| "The cytokinetics of subcutaneous metastases in five patients with melanoma was studied." | 1.25 | Cell proliferation in human melanoma. ( Frei, E; Luce, JK; Shirakawa, S; Tannock, I, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 79 (80.61) | 18.7374 |
| 1990's | 12 (12.24) | 18.2507 |
| 2000's | 7 (7.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davila, M | 1 |
| Frost, AR | 1 |
| Grizzle, WE | 1 |
| Chakrabarti, R | 1 |
| Shim, BS | 1 |
| Park, KK | 1 |
| Choi, SH | 1 |
| Akiyama, S | 1 |
| Furukawa, T | 1 |
| Sumizawa, T | 1 |
| Takebayashi, Y | 1 |
| Nakajima, Y | 1 |
| Shimaoka, S | 1 |
| Haraguchi, M | 1 |
| Moro, L | 1 |
| Arbini, AA | 1 |
| Marra, E | 1 |
| Greco, M | 1 |
| Mazzarino, C | 1 |
| Nicosia, A | 1 |
| Garraffo, C | 1 |
| Tantillo, F | 1 |
| Monte, V | 1 |
| Girlando, A | 1 |
| Malaponte, G | 1 |
| Qiao, M | 1 |
| Shapiro, P | 1 |
| Fosbrink, M | 1 |
| Rus, H | 1 |
| Kumar, R | 1 |
| Passaniti, A | 1 |
| Thejass, P | 1 |
| Kuttan, G | 1 |
| Magrassi, B | 1 |
| Pagani, G | 1 |
| Roveta, G | 1 |
| Tannock, IF | 1 |
| Sternberg, A | 1 |
| Petrelli, NJ | 1 |
| Au, J | 1 |
| Rustum, Y | 1 |
| Mittelman, A | 1 |
| Creaven, P | 1 |
| Donelli, MG | 1 |
| D'Incalci, M | 2 |
| Garattini, S | 1 |
| Erba, E | 1 |
| Vaghi, M | 1 |
| Morasca, L | 1 |
| Willnow, U | 2 |
| Meyer, JS | 1 |
| Tubiana, M | 3 |
| Pejovic, MJ | 1 |
| Renaud, A | 1 |
| Contesso, G | 1 |
| Chavaudra, N | 1 |
| Gioanni, J | 1 |
| Malaise, EP | 2 |
| Gemsa, D | 1 |
| Kramer, W | 1 |
| Napierski, I | 1 |
| Bärlin, E | 1 |
| Till, G | 1 |
| Resch, K | 1 |
| Giraldi, T | 1 |
| Sava, G | 1 |
| Cuman, R | 1 |
| Nisi, C | 1 |
| Lassiani, L | 1 |
| Tanigawa, N | 1 |
| Masuda, Y | 1 |
| Shimomatsuya, T | 1 |
| Fujii, H | 1 |
| Muraoka, R | 1 |
| Tanaka, T | 1 |
| Kikuchi, K | 1 |
| Nakagawa, H | 1 |
| Kadono, T | 1 |
| Etoh, T | 1 |
| Byers, HR | 1 |
| Mihm, MC | 1 |
| Tamaki, K | 1 |
| Silvestrini, R | 5 |
| Daidone, MG | 3 |
| Luisi, A | 1 |
| Mastore, M | 1 |
| Leutner, M | 1 |
| Salvadori, B | 2 |
| Amadori, D | 1 |
| Volpi, A | 1 |
| Maltoni, R | 1 |
| Nanni, O | 1 |
| Amaducci, L | 1 |
| Amadori, A | 1 |
| Giunchi, DC | 1 |
| Vio, A | 1 |
| Saragoni, A | 1 |
| Bonfil, RD | 1 |
| Bustuoabad, OD | 1 |
| Binda, MM | 1 |
| Mizuno, N | 1 |
| Kato, Y | 2 |
| Izumi, Y | 1 |
| Irimura, T | 2 |
| Sugiyama, Y | 2 |
| Shirota, K | 1 |
| Kondo, H | 1 |
| Cohen, IR | 1 |
| Feldman, M | 1 |
| Emanuel', NM | 1 |
| Kiseleva, EG | 1 |
| D'iachkovskaia, RF | 1 |
| Konovalova, NP | 1 |
| Volkova, IM | 1 |
| Hainau, B | 1 |
| Dombernowsky, P | 1 |
| Hansen, HH | 1 |
| Borgeskov, S | 1 |
| Schiffer, LM | 2 |
| Braunschweiger, PG | 1 |
| Stragand, JJ | 1 |
| Hasegawa, H | 1 |
| Shapiro, WR | 1 |
| Posner, JB | 1 |
| Basler, G | 1 |
| Woodhead, AD | 1 |
| Setlow, RB | 1 |
| Scully, PM | 1 |
| Sirachý, J | 1 |
| Frei, E | 4 |
| Nicolini, C | 1 |
| Simpson-Herren, L | 2 |
| Holmquist, JP | 2 |
| Jaffe, N | 1 |
| Tattersall, MH | 1 |
| Pitman, S | 1 |
| Parker, L | 1 |
| Bastert, G | 1 |
| Schmidt-Matthiesen, H | 1 |
| Gerner, R | 1 |
| Michel, RT | 1 |
| Nord, D | 1 |
| Leppien, G | 1 |
| Kaplan, MS | 1 |
| Mino, FO | 1 |
| Kummerfeld, KB | 1 |
| Lundak, RL | 1 |
| Petersen, OW | 1 |
| Rønnov-Jessen, L | 1 |
| Howlett, AR | 1 |
| Bissell, MJ | 1 |
| Ishiwata, K | 1 |
| Takahashi, T | 1 |
| Iwata, R | 1 |
| Tomura, M | 1 |
| Tada, M | 1 |
| Itoh, J | 1 |
| Kameyama, M | 1 |
| Ido, T | 1 |
| Lu, C | 1 |
| Vickers, MF | 1 |
| Kerbel, RS | 2 |
| Valentinis, B | 1 |
| Di Fronzo, G | 1 |
| Coradini, D | 1 |
| Pogány, G | 1 |
| Cserháti, T | 1 |
| Oláh, J | 1 |
| Valkó, K | 1 |
| Theodorescu, D | 1 |
| Caltabiano, M | 1 |
| Greig, R | 1 |
| Rieman, D | 1 |
| Courdi, A | 1 |
| Khoo, SK | 1 |
| Hurst, T | 1 |
| Lark, J | 1 |
| Webb, MJ | 1 |
| Parsons, P | 1 |
| Mackay, EV | 1 |
| Buroker, TR | 1 |
| Moertel, CG | 1 |
| Fleming, TR | 1 |
| Everson, LK | 1 |
| Cullinan, SA | 1 |
| Krook, JE | 1 |
| Mailliard, JA | 1 |
| Marschke, RF | 1 |
| Klaassen, DJ | 1 |
| Laurie, JA | 1 |
| Deichman, GI | 1 |
| Vendrov, EL | 1 |
| Cresson, DH | 1 |
| Beckman, WC | 1 |
| Tidwell, RR | 1 |
| Geratz, JD | 1 |
| Siegal, GP | 1 |
| Koscielny, S | 1 |
| Zaffaroni, N | 1 |
| Sanfilippo, O | 1 |
| Bolis, G | 1 |
| Seminara, P | 1 |
| Costa, A | 1 |
| Grignolio, E | 1 |
| Clemente, C | 1 |
| Attili, A | 1 |
| Testori, A | 1 |
| Nicoletti, G | 1 |
| Brambilla, P | 1 |
| De Giovanni, C | 1 |
| Lollini, PL | 1 |
| Del Re, B | 1 |
| Marocchi, A | 1 |
| Mocarelli, P | 1 |
| Prodi, G | 1 |
| Nanni, P | 1 |
| Lynch, G | 1 |
| Kemeny, N | 1 |
| Chun, H | 1 |
| Martin, D | 1 |
| Young, C | 1 |
| Park, SK | 1 |
| Brody, JI | 2 |
| Wallace, HA | 1 |
| Blakemore, WS | 1 |
| Pisciotta, AV | 1 |
| Brachetti, A | 1 |
| Leonhardt, A | 1 |
| Limburg, H | 1 |
| Osswald, H | 1 |
| Schmähl, D | 1 |
| Wolberg, WH | 2 |
| Duprez, A | 1 |
| Bessot, M | 1 |
| Stempfler, A | 1 |
| Watkins, E | 2 |
| Ogata, Y | 1 |
| Anderson, LL | 1 |
| Waters, MF | 1 |
| Choné, B | 2 |
| Modjanova, EA | 1 |
| Malenkov, AG | 1 |
| Blomgren, H | 1 |
| Glas, U | 1 |
| Franzén, S | 1 |
| Granberg, PO | 1 |
| Dolezalová, V | 1 |
| Feit, J | 1 |
| Simícková, M | 1 |
| Burstein, NA | 1 |
| Carey, RW | 1 |
| Muckle, DS | 1 |
| Mavligit, GM | 1 |
| Hersh, EM | 1 |
| McBride, CM | 1 |
| McCredie, JA | 1 |
| Inch, WR | 1 |
| Sutherland, RM | 1 |
| Buda, JA | 1 |
| Suciu-Foca, N | 1 |
| Reemtsma, KB | 1 |
| Warren, BA | 1 |
| Straus, MJ | 1 |
| Kölmel, HW | 1 |
| Catalona, WJ | 2 |
| Sample, WF | 3 |
| Chretien, PB | 3 |
| Crowder, WL | 1 |
| Gertner, HR | 2 |
| Zeidman, I | 1 |
| Chess, L | 1 |
| Bock, GN | 1 |
| Ungaro, PC | 1 |
| Buchholz, DH | 1 |
| Mardiney, MR | 1 |
| Hussa, RO | 1 |
| Pattillo, RA | 1 |
| Delfs, FE | 1 |
| Mattingly, RF | 1 |
| Pullmann, H | 1 |
| Steigleder, GK | 1 |
| Goldman, LI | 1 |
| Flaxman, BA | 1 |
| Wernick, G | 1 |
| Zabriskie, JB | 1 |
| Sanford, AH | 1 |
| Huber, C | 1 |
| Huber, H | 1 |
| Gföller, A | 1 |
| Michlamyr, G | 1 |
| Braunsteiner, H | 1 |
| Robinson, MR | 1 |
| Nakhla, LS | 1 |
| Whitaker, RH | 1 |
| Yokota, M | 1 |
| Terz, JJ | 1 |
| Curutchet, HP | 1 |
| Lawrence, W | 1 |
| Tannock, I | 2 |
| Hagemann, RF | 1 |
| Owen, LN | 1 |
| Steel, GG | 2 |
| Lamerton, LF | 1 |
| Shirakawa, S | 1 |
| Luce, JK | 1 |
| Matovinovic, J | 1 |
| Nishiyama, RH | 1 |
| Lalli, A | 1 |
| Poissant, G | 1 |
| Hofer, KG | 1 |
| Hofer, M | 1 |
| Cleaver, JE | 1 |
| Fettig, O | 1 |
| Oehlert, W | 1 |
| Clarkson, B | 1 |
| Ota, K | 1 |
| Ohkita, T | 1 |
| O'Connor, A | 1 |
| Karrer, K | 1 |
| Rubini, JR | 1 |
7 reviews available for thymidine and Metastase
| Article | Year |
|---|---|
The role of thymidine phosphorylase, an angiogenic enzyme, in tumor progression.
Topics: Angiogenesis Inducing Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Ce | 2004 |
Tumor cell population kinetics following noncurative treatment.
Topics: Animals; Cell Division; Humans; Kinetics; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Neoplasm Metasta | 1978 |
Methotrexate revisited.
Topics: Adolescent; Adult; Alkalies; Aminopterin; Animals; Bone Marrow; Bone Neoplasms; Drug Therapy, Combin | 1976 |
Cell proliferation kinetics in human solid tumors: relation to probability of metastatic dissemination and long-term survival.
Topics: Autoradiography; Cell Division; Flow Cytometry; Humans; Interphase; Neoplasm Metastasis; Neoplasms; | 1989 |
Myelopoiesis in vitro.
Topics: Amino Acids; Animals; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Clone Cells; Colchicine; Cul | 1968 |
Environment of the blood-borne tumor embolus adherent to vessel wall.
Topics: Animals; Aorta; Autoradiography; Basement Membrane; Blood Vessels; Embolism; Endothelium; Fibrin; Fi | 1973 |
The growth characteristics of lung cancer and its application to treatment design.
Topics: Cell Division; Cell Movement; Humans; Lung Neoplasms; Mitosis; Neoplasm Metastasis; Prognosis; Radio | 1974 |
1 trial available for thymidine and Metastase
| Article | Year |
|---|---|
A controlled evaluation of recent approaches to biochemical modulation or enhancement of 5-fluorouracil therapy in colorectal carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Colonic Neoplasms; Drug Evaluat | 1985 |
90 other studies available for thymidine and Metastase
| Article | Year |
|---|---|
LIM kinase 1 is essential for the invasive growth of prostate epithelial cells: implications in prostate cancer.
Topics: Actin Depolymerizing Factors; Cell Division; Cell Line; Cell Line, Tumor; Cell Separation; DNA; DNA- | 2003 |
Anti-metastatic effects of fuzhengfangaitang on human fibrosarcoma cells HT1080.
Topics: Antineoplastic Agents, Phytogenic; Blotting, Western; Cell Survival; Fibrosarcoma; Gelatin; Gelatina | 2003 |
Down-regulation of BRCA2 expression by collagen type I promotes prostate cancer cell proliferation.
Topics: BRCA2 Protein; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Collagen Type I; DNA; DNA Repair | 2005 |
Interleukin-2 receptors in patients with lung carcinoma metastasis undergoing treatment with disodium-clodronate. Preliminary research.
Topics: Bone Density Conservation Agents; Clodronic Acid; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; | 1989 |
Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation.
Topics: Animals; Base Sequence; Blotting, Western; Bone Marrow Cells; CDC2 Protein Kinase; Cell Cycle; Cell | 2006 |
Antimetastatic activity of Sulforaphane.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brassica; Cell Line; Cell Proliferation; Collagen | 2006 |
[Autoradiographic studies with thymidine-H3 in Oberling's aleukemic myeloma in rats, during bone invasion].
Topics: Animals; Autoradiography; Bone Neoplasms; DNA; Neoplasm Metastasis; Plasmacytoma; Rats; Thymidine; T | 1967 |
Biology and tumor growth.
Topics: Animals; Antineoplastic Agents; Autoradiography; Cell Cycle; Cell Division; Clone Cells; Flow Cytome | 1983 |
A combination of 5-fluorouracil and thymidine in advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Colonic Neoplasms; Drug Sy | 1984 |
Pharmacokinetic studies of anticancer drugs in tumor-bearing animals.
Topics: Animals; Antineoplastic Agents; Cell Line; Dose-Response Relationship, Drug; Half-Life; Humans; Kine | 1984 |
In vitro cytotoxicity of VP 16 on primary tumor and metastasis of Lewis lung carcinoma.
Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Lung Neoplasms | 1982 |
Autoradiographic in vitro study of the cell kinetics of osteogenic sarcomas and Ewing's sarcomas in children.
Topics: Autoradiography; Child; Culture Techniques; Humans; Kinetics; Neoplasm Metastasis; Osteosarcoma; Sar | 1982 |
Potential value of cell kinetics in management of cancers of unknown origin.
Topics: Autoradiography; Cell Division; Humans; Kinetics; Neoplasm Metastasis; Neoplasms; Thymidine; Tritium | 1982 |
Kinetic parameters and the course of the disease in breast cancer.
Topics: Breast Neoplasms; Cell Division; Female; Follow-Up Studies; Humans; Kinetics; Neoplasm Metastasis; P | 1981 |
Potentiation of macrophage tumor cytostasis by tumor-induced ascites.
Topics: Animals; Ascites; Caseins; Cell Transformation, Neoplastic; DNA; Female; Kinetics; Lymphoma; Macroph | 1981 |
Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplas | 1981 |
Thymidine uptake in vitro as a prognostic indicator for primary gastric cancer.
Topics: Aged; Female; Humans; Male; Middle Aged; Multivariate Analysis; Neoplasm Invasiveness; Neoplasm Meta | 1993 |
Decreased ET(B) receptor expression in human metastatic melanoma cells.
Topics: Amino Acid Sequence; Cell Line; DNA, Neoplasm; Endothelins; Gene Expression; Humans; Kinetics; Melan | 1996 |
Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index.
Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Cell Division; Confidence Intervals; DNA, Neoplasm | 1997 |
Cell proliferation as a predictor of response to chemotherapy in metastatic breast cancer: a prospective study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclop | 1997 |
Antiangiogenesis and apoptosis as mediators of concomitant tumor resistance induced by Calu-6, a human lung carcinoma cell line, in nude mice.
Topics: Animals; Apoptosis; Cell Division; Cell Line; DNA, Neoplasm; Humans; Immunity, Innate; Lung Neoplasm | 1998 |
Importance of hepatic first-pass removal in metastasis of colon carcinoma cells.
Topics: Animals; Cell Line; Colonic Neoplasms; Humans; Kinetics; Liver Neoplasms; Male; Mathematics; Mice; M | 1998 |
Anti-metastatic effect of the sialyl Lewis-X analog GSC-150 on the human colon carcinoma derived cell line KM12-HX in the mouse.
Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Line; Colonic Neoplasms; Glycosphingolipids; Hum | 2001 |
Cellular interactions controlling the immune reactivity of T-lymphocytes.
Topics: Animals; B-Lymphocytes; Binding Sites, Antibody; Bone Marrow Cells; Cell Differentiation; Concanaval | 1975 |
[A kinetic analysis of the growth of transplanted tumors and their metastasis].
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; DNA, Neoplasm; Kinetics; Liver Neoplasms; | 1975 |
Cell proliferation and histologic classification of bronchogenic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cel | 1977 |
Effect of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride on experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Drug Evaluation, Preclinical; Ependymoma | 1979 |
Migration of intraperitoneally injected thyroid cells in the Amazon molly, Poecilia formosa.
Topics: Animals; Autoradiography; Cell Movement; Fishes; Injections, Intraperitoneal; Methods; Neoplasm Meta | 1979 |
An approach to the problem of heterogeneity of human tumour-cell populations.
Topics: Antineoplastic Agents; Cell Nucleus; Chromosomes, Human; Female; Humans; Mitosis; Neoplasm Metastasi | 1979 |
The effect of hyperthermia 42.5 degrees C on the incorporation of 3H-thymidine into the DNA of solid tumours in childhood.
Topics: Adolescent; Cells, Cultured; Child; Child, Preschool; DNA, Neoplasm; Humans; In Vitro Techniques; In | 1979 |
The principles and methods of cell synchronization in cancer chemotherapy.
Topics: Animals; Cell Division; Cell Line; Colchicine; Computers; Cytarabine; DNA Replication; Esophagus; Hu | 1976 |
Effects of surgery on the cell kinetics of residual tumor.
Topics: Animals; Cell Division; Cell Survival; Kinetics; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inb | 1976 |
New approaches to cancer chemotherapy with methotrexate.
Topics: Adult; Animals; Biological Transport; Bone Marrow; Creatinine; DNA, Neoplasm; Doxorubicin; Drug Ther | 1975 |
[In-vitro testing of the sensitivity of mammary carcinoma cells to cytostatic drugs (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclophosphamide; Female; Humans; In Vitro T | 1975 |
Phytohemagglutinin-stimulated immune response. Assay in colorectal carcinoma patients.
Topics: Adult; Aged; Carcinoma; Colonic Neoplasms; Humans; Immunity, Cellular; Lectins; Lymphocytes; Middle | 1975 |
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.
Topics: Basement Membrane; Breast; Breast Neoplasms; Cell Differentiation; Cell Division; Cells, Cultured; C | 1992 |
Tumor diagnosis by PET: potential of seven tracers examined in five experimental tumors including an artificial metastasis model.
Topics: Animals; Carbon Radioisotopes; Deoxyglucose; Diagnosis, Differential; Disease Models, Animal; Floxur | 1992 |
Interleukin 6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Growth Inhibitors; Humans; Inter | 1992 |
Biological characterisation of primary and metachronous lesions in breast cancer patients.
Topics: Breast Neoplasms; Cell Division; Female; Humans; Mitosis; Neoplasm Metastasis; Neoplasm Recurrence, | 1992 |
Relationships between the chromatographic retention data and the effects of nucleoside derivatives in highly metastatic 3LL cells.
Topics: Animals; Chromatography, Thin Layer; DNA, Neoplasm; Lung Neoplasms; Neoplasm Metastasis; Nucleosides | 1992 |
Reduction of TGF-beta activity abrogates growth promoting tumor cell-cell interactions in vivo.
Topics: Adenocarcinoma; Animals; Antibodies; Cell Communication; Cell Division; Cell Line; Culture Media, Se | 1991 |
In vitro sensitivity of ovarian cancer as determined by a short-term biochemical assay: comparison between primary and metastatic sites in the same patient.
Topics: Cisplatin; Drug Screening Assays, Antitumor; Female; Humans; Neoplasm Metastasis; Ovarian Neoplasms; | 1989 |
Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity.
Topics: Adenoviridae; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cri | 1986 |
In vitro inhibition of human sarcoma cells' invasive ability by bis(5-amidino-2-benzimidazolyl)methane--a novel esteroprotease inhibitor.
Topics: Amnion; Animals; Benzimidazoles; Cell Count; Cell Division; Cell Movement; Cells, Cultured; Collagen | 1986 |
Cell kinetics, growth rate and the natural history of breast cancer. The Heuson Memorial Lecture.
Topics: Breast Neoplasms; Cell Division; DNA, Neoplasm; Female; Humans; Interphase; Lymph Nodes; Lymphatic M | 1988 |
Drug sensitivity of different tumor lesions from the same patient evaluated by a short-term assay.
Topics: Antineoplastic Agents; DNA, Neoplasm; Drug Screening Assays, Antitumor; Humans; Neoplasm Metastasis; | 1988 |
Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin.
Topics: Adolescent; Adult; Aged; Cell Division; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metast | 1987 |
Colony-stimulating activity from the new metastatic TS/A cell line and its high- and low-metastatic clonal derivatives.
Topics: Animals; Bone Marrow; Cell Differentiation; Cell Division; Cell Line; Colony-Stimulating Factors; Fe | 1985 |
Phase I evaluation and pharmacokinetic study of weekly iv thymidine and 5-FU in patients with advanced colorectal carcinoma.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Drug Administration | 1985 |
Immunosuppressive effect of surgery.
Topics: Adult; Aged; Carbon Isotopes; DNA; Heart Diseases; Humans; Immunity; In Vitro Techniques; Lectins; L | 1971 |
[Clinical experiences with a combination therapy of metastasising genital and mammary carcinomas (author's transl)].
Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Cyclophosphamide; Cytidine; Drug Therapy, Combination; Fem | 1974 |
Determinants of human tumor sensitivity to fluorinated pyrimidine chemotherapy.
Topics: DNA, Neoplasm; Floxuridine; Fluorouracil; Humans; In Vitro Techniques; Ligases; Neoplasm Metastasis; | 1967 |
[Determination, on histologic sections, of specific activities of H3-DNA and H3-RNA synthesized in vivo by normal and cancerous human tissues].
Topics: Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Gallbladder Neoplasms; Humans; Liver; Liver Neoplasms | 1969 |
Activation of host lymphocytes cultured with cancer cells treated with neuraminidase.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Culture Tec | 1971 |
Biochemical approaches to prediction of response in solid tumors.
Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Carcinoma, Squamo | 1971 |
[Results of tumor-cell kinetic studies within the scope of puncture cytology].
Topics: Acridines; Antineoplastic Agents; Ascitic Fluid; Autoradiography; Biopsy; Cell Movement; Female; Gol | 1972 |
Alteration of properties of cell contacts during progression of hepatomas.
Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cations, Divalent; Cell Adhesion; Cell Separation; Cont | 1973 |
Lymphoid cells in carcinoma of the breast. Failure of response to phytohaemagglutinin in vitro.
Topics: Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Cells, Cultured | 1973 |
Appearance of alpha-fetoprotein in rat serum during induction of primary hepatoma with regard to development of histological changes in liver tissue.
Topics: Adenoma, Bile Duct; Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Cell Nucleus | 1974 |
In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation.
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Aged; Animals; Breast Neoplasms; Carcinoma; Carcin | 1974 |
Response of a musculo-skeletal tumour to combined radiation therapy. An in vitro/vivo investigation.
Topics: Animals; Cell Line; Glycolysis; Hot Temperature; Lymphatic Metastasis; Methotrexate; Models, Biologi | 1974 |
Lymphocyte blastogenesis induced by autochthonous human solid tumor cells: relationship to stage of disease and serum factors.
Topics: Adolescent; Adult; Antigens, Neoplasm; Blood; Humans; Lymphocyte Activation; Lymphocytes; Neoplasm M | 1974 |
Peripheral blood lymphocytes and breast cancer.
Topics: Adult; Age Factors; Breast Neoplasms; Carcinoma; Female; Humans; Leukocyte Count; Lymphocyte Activat | 1973 |
Impaired cell-mediated immunity in patients with cancer.
Topics: Breast Neoplasms; Cells, Cultured; Gastrointestinal Neoplasms; Humans; Immunity, Cellular; Lectins; | 1974 |
[Differential cytodiagnosis of tumor cells in cerebrospinal fluid].
Topics: Adult; Autoradiography; Carcinoma; Cerebellar Neoplasms; Cerebrospinal Fluid; Cytodiagnosis; Humans; | 1972 |
Lymphocyte reactivity in cancer patients: correlation with tumor histology and clinical stage.
Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Antilymphocyte Serum; Carcinoma; Carcinoma, Sq | 1973 |
Correlation of preoperative lymphocyte reactivity with the clinical course of cancer patients.
Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Follow-Up Studies; H | 1973 |
Effect of 5-bromodeoxyuridine (BUdR) on experimental metastasis.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Clone Cells; Dose-Response Relationship, Drug; Ido | 1973 |
Immunologic effects of BCG in patients with malignant melanoma: specific evidence for stimulation of the 'secondary' immune response.
Topics: Adult; Antibody Formation; BCG Vaccine; Candida; Complement System Proteins; Female; Humans; Hyperse | 1973 |
Actinomycin D stimulation of HCG production by human choriocarcinoma.
Topics: Animals; Carbon Radioisotopes; Cattle; Cell Line; Cells, Cultured; Choriocarcinoma; Chorionic Gonado | 1973 |
A study of cellular inflammatory reaction in human malignant melanoma, using in vitro-labelling techniques with h3-thymidine.
Topics: Biopsy; Connective Tissue Cells; DNA; Humans; Immunity, Active; Lymphocytes; Macrophages; Mast Cells | 1974 |
Immune surveillance and tumor dissemination: in vitro comparison of the B16 melanoma in primary and metastatic form.
Topics: Animals; Antigens, Neoplasm; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells; Cells, Cu | 1974 |
Cell population kinetics of transplanted and metastatic Lewis lung carcinoma.
Topics: Animals; Autoradiography; Cell Division; DNA, Neoplasm; Hybridization, Genetic; L-Lactate Dehydrogen | 1974 |
[DNS synthesizing lymphocytes in patients with carcinoma].
Topics: Autoradiography; Blood Cell Count; Breast Neoplasms; Bronchial Neoplasms; DNA, Neoplasm; Female; His | 1971 |
Inhibition of phytohemagglutinin-induced in vitro lymphocyte transformation by serum from patients with carcinoma.
Topics: ABO Blood-Group System; Adenocarcinoma; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Culture | 1971 |
Lymphocyte transformation inb carcinoma of the prostate.
Topics: Acid Phosphatase; Aged; Culture Techniques; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Mal | 1971 |
[A DNA-synthesis inhibiting substance in the human tumor tissues].
Topics: Amnion; Cell Line; Cell-Free System; Chondroitin; DNA, Neoplasm; Heparin; Humans; Hyaluronic Acid; L | 1971 |
Analysis of the cell kinetics of human solid tumors.
Topics: Adult; Aged; Biopsy; Bone Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Colo | 1971 |
Possible role of cell kinetics in prediction of the response to cancer therapy.
Topics: Animals; Antineoplastic Agents; Autoradiography; Drug Resistance; Humans; Mammary Neoplasms, Experim | 1971 |
Cell kinetic analysis of a human melanoma in vitro and in vivo-vitro.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Carbon Isotopes; Culture Techniques; DNA, Neo | 1971 |
The growth and cell population kinetics of spontaneous tumours in domestic animals.
Topics: Animals; Autoradiography; Cat Diseases; Cats; DNA, Neoplasm; Dog Diseases; Dogs; Female; Kidney Neop | 1969 |
Cell population kinetics and chemotherapy. I. The kinetics of tumor cell populations.
Topics: Animals; Autoradiography; Cell Division; DNA, Neoplasm; Dog Diseases; Dogs; Humans; Kinetics; Lung N | 1969 |
Cell proliferation in human melanoma.
Topics: Adult; Aged; Autoradiography; Biopsy; Cell Division; DNA, Neoplasm; Female; Humans; Male; Melanoma; | 1970 |
"Benign metastasizing goiter" of Cohnheim: an experimental study with the transplantable thyroid tumor of the rat.
Topics: Animals; Autoradiography; Cell Differentiation; Cell Transformation, Neoplastic; Diet; Femur; Goiter | 1971 |
Kinetics of proliferation, migration, and death of L1210 ascites cells.
Topics: Animals; Ascitic Fluid; Autoradiography; Cell Count; Cell Division; Cell Movement; Cell Survival; DN | 1971 |
Defective repair replication of DNA in xeroderma pigmentosum.
Topics: Autoradiography; Bromodeoxyuridine; Centrifugation, Density Gradient; DNA Replication; Fibroblasts; | 1968 |
[Current data on human tumor kinetics].
Topics: Animals; Ascites; Biopsy; Humans; Kinetics; Leukemia; Lung Neoplasms; Mammary Neoplasms, Experimenta | 1969 |
[Radioautographic metabolic studies with tritium-labeled substances in tumor tissues of the human uterus].
Topics: Adenocarcinoma; Autoradiography; Carcinoma, Squamous Cell; DNA, Neoplasm; Female; Humans; Neoplasm M | 1965 |
Kinetics of proliferation of cancer cells in neoplastic effusions in man.
Topics: Adenocarcinoma; Antineoplastic Agents; Autoradiography; Cell Division; DNA, Neoplasm; Exudates and T | 1965 |
On the fate of labelled Ehrlich ascites cells in mice, an autoradiographic study using H3 thymidine.
Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; In Vitro Techniques; Injections, | 1965 |