thymidine has been researched along with Melanoma in 195 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
Excerpt | Relevance | Reference |
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"Here, we examined the potential of blocking the thymidine de novo synthesis pathways for sensitizing melanoma cells to the nucleoside salvage pathway targeting endogenous DNA irradiation." | 7.85 | Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma. ( Drude, N; El Moussaoui, L; Kaiser, HJ; Miran, T; Morgenroth, A; Mottaghy, FM; Vogg, ATJ; von Felbert, V, 2017) |
" Although the two agents may interact in the biosynthetic pathway for thymidine, we investigated, as an alternative mechanism, the regulation of susceptibility of the A375 human melanoma to natural killers activated by interferon." | 7.68 | Abrogation of interferon-induced resistance to interferon-activated major histocompatibility complex-unrestricted killers by treatment of a melanoma cell line with 5-fluorouracil. ( Glass, J; Neefe, JR, 1991) |
"A sulfur-containing amino acid compound, S-allyl cysteine (SAC), derived from garlic extract inhibited proliferation of nine human and murine melanoma cell line in a dose-dependent manner (1." | 7.68 | Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine. ( Hoon, DS; Irie, RF; Morton, DL; Saxton, RE; Takeyama, H, 1993) |
"The effect of tamoxifen on the growth of malignant melanoma was investigated using human cell lines and single-cell suspensions prepared from patients' tumours cultured in soft agar." | 7.67 | The effect of tamoxifen on the growth of human malignant melanoma in vitro. ( De Young, NJ; Gill, PG; Horsfall, DJ; Keightley, DD; Thompson, A, 1984) |
"The cytotoxic effect of cis-diamminedichloroplatinum(II) (cis-DDP), as measured by a dye exclusion assay was much more pronounced in bone marrow cells and phytohemagglutinin (PHA)-stimulated lymphocytes than in a human melanoma cell line." | 7.67 | Cis-diamminedichloroplatinum(II) toxicity in human melanoma cells and lymphocytes as related to cellular platinum accumulation, DNA cross-linking and inhibition of DNA synthesis. ( Hansson, J; Lewensohn, R; Ringborg, U, 1988) |
"Sodium cyanate injected IP at a dose level of 200 or 250 mg/kg caused a 90% or greater inhibition of the incorporation of [3H]thymidine into DNA of B16 melanoma transplanted SC in mice." | 7.67 | Effects of sodium cyanate in mice bearing B16 melanoma. ( Carpenter, L; Hill, GJ; Hill, HZ; Lea, MA; Luke, A; Martinson, CF; Velazquez, O, 1986) |
"In the human melanoma cell line MM127 , the melphalan survival curve was linear and exhibited reciprocity with respect to concentration and treatment time." | 7.67 | Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. ( Parsons, PG, 1984) |
"0 microCi/ml (methyl-3H)thymidine (3H-TdR) the growth rate of 6 human melanoma lines and 1 subline progressively slowed then stopped, a change that was accompanied by loss of reproductive viability as assessed by colony formation in agar, but unaccompanied by a comparable inhibition of thymidine incorporation." | 7.66 | Tritiated-thymidine-induced increased DNA content and irreversible differentiation in a human melanoma cell line. ( Sheridan, JW; Simmons, RJ, 1981) |
"3,4-Dihydroxybenzylamine (DHBA), a dopamine analog, was much less toxic than dopamine when tested against the B16 melanoma in vivo and in vitro." | 7.66 | 3,4-Dihydroxybenzylamine: a dopamine analog with enhanced antitumor activity against B16 melanoma. ( Wick, MM, 1979) |
"The effect of thymidine (TdR) on the growth of a human melanoma transplanted in nude mice has been studied." | 7.65 | Effect of excess thymidine on the growth of human melanoma cells transplanted in thymus deficient nude mice. ( Giovanella, BC; Lee, SS; Stehlin, JS, 1977) |
"Cultured human malignant melanoma cells, when added to normal human lymphocytes stimulated to proliferate by mitogen or antigen, were found to inhibit the uptake of 3H-thymidine (3H-T) by the lymphocytes." | 7.65 | Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes. ( Dent, PB; Liao, SK; Lui, VK, 1977) |
"Fusarochromanone has been shown to have both stimulatory and inhibitory effects on various mammalian cells, depending on the concentration used." | 5.34 | Inhibitory effects of fusarochromanone on melanoma growth. ( Culberson, C; Dréau, D; Foster, M; Hogg, M; Nunes, P; Wuthier, RE, 2007) |
" Dose-response curves were determined using a 5-day incubation period and 6-h terminal [3H]thymidine-labelling period." | 5.29 | Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays. ( Baguley, BC; Finlay, GJ; Holdaway, KM; Marshall, ES; Matthews, JH; Nixon, J; Shaw, JH; Tumewu, P, 1994) |
"[3H]Thymidine uptake was inhibited by 12%, but no inhibition was detected in [3H]thymidine incorporation." | 5.27 | High-dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line. ( DiSorbo, DM; Nathanson, L, 1983) |
"Kinetics of immunological parameters such as natural killer (NK) cell activity and tritium-thymidine uptake rate of T lymphocytes by phytohemagglutinin stimulation were investigated using peripheral leukocyte fractions of melanoma patients treated with hyperthermic isolated limb perfusion (HILP)." | 5.08 | Kinetics of immunological parameters in patients with malignant melanoma treated with hyperthermic isolated limb perfusion. ( Hori, Y; Mashino, T; Matsuda, K; Mayumi, H; Nagae, S; Nakao, T; Nakayama, J; Takahashi, S; Tominaga, R; Yasui, H, 1997) |
"Here, we examined the potential of blocking the thymidine de novo synthesis pathways for sensitizing melanoma cells to the nucleoside salvage pathway targeting endogenous DNA irradiation." | 3.85 | Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma. ( Drude, N; El Moussaoui, L; Kaiser, HJ; Miran, T; Morgenroth, A; Mottaghy, FM; Vogg, ATJ; von Felbert, V, 2017) |
"The effect of congeners of nitrogen monoxide (NO) on iron (Fe) uptake from 59Fe-125I-transferrin (Tf) and release of 59Fe from prelabelled cells have been investigated in SK-MEL-28 human melanoma cells, human K562 cells and mouse MDW-4 cells." | 3.69 | Nitrogen monoxide decreases iron uptake from transferrin but does not mobilise iron from prelabelled neoplastic cells. ( Neumannova, V; Ponka, P; Richardson, DR, 1995) |
"We used computerized image analysis, immunohistochemistry, and the incorporation of tritiated thymidine to study the relationship between nuclear size and shape and the proliferation of malignant melanoma cells." | 3.69 | Karyometry of primary and metastatic malignant melanoma. A correlation with cell proliferation. ( Piérard, GE; Piérard-Franchimont, C, 1994) |
"Uptake of tritiated thymidine, L-leucine, L-methionine and FDG into two human tumor cell lines (HTB 63 melanoma and HTB 77 IP3 ovarian carcinoma) was determined after a 4-hr exposure to each of three different oxygen atmospheres (0, 1." | 3.69 | Effects of hypoxia on the uptake of tritiated thymidine, L-leucine, L-methionine and FDG in cultured cancer cells. ( Clavo, AC; Wahl, RL, 1996) |
" Although the two agents may interact in the biosynthetic pathway for thymidine, we investigated, as an alternative mechanism, the regulation of susceptibility of the A375 human melanoma to natural killers activated by interferon." | 3.68 | Abrogation of interferon-induced resistance to interferon-activated major histocompatibility complex-unrestricted killers by treatment of a melanoma cell line with 5-fluorouracil. ( Glass, J; Neefe, JR, 1991) |
" Some boron compounds have recently been proposed for BNCT of malignant melanomas; the synthesized L- and D- forms of carboranylalanine and the previously tested compound L-p-boronophenylalanine are candidates." | 3.68 | Penetration and binding of L- and D-carboranylalanine in human melanoma spheroids. ( Carlsson, J; Lindström, P; Olsson, P; Pettersson, OA; Sjöberg, S, 1993) |
"A sulfur-containing amino acid compound, S-allyl cysteine (SAC), derived from garlic extract inhibited proliferation of nine human and murine melanoma cell line in a dose-dependent manner (1." | 3.68 | Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine. ( Hoon, DS; Irie, RF; Morton, DL; Saxton, RE; Takeyama, H, 1993) |
"The prognostic role of cell kinetics (expressed as 3H-thymidine labelling index, 3H-TdR LI) was assessed on 145 patients with pathologic stage II melanoma subjected only to therapeutic lymph node dissection." | 3.68 | Cell kinetics: an independent prognostic variable in stage II melanoma of the skin. ( Cascinelli, N; Clemente, C; Costa, A; Grignolio, E; Mezzanotte, G; Silvestrini, R; Vaglini, M, 1990) |
"Intracellular deoxyribonucleotide pools were examined before and after thymidine treatment in highly sensitive T-lymphoid cells, relatively resistant B-lymphoid cells and moderately sensitive melanoma cells." | 3.67 | Diverse deoxyribonucleotide profiles in cultured human cells with differential sensitivity to thymidine. ( Appel, H; Leyva, A; Pinedo, HM, 1984) |
"The rates of incorporation of 2-14C-thymidine into DNA of melanoma B16, bone marrow, gastrointestinal mucosa, spleen and liver at various time after administration of dianhydrogalactitol (DAG), 3,4-diacetyldianhydrogalactitol (DiacDAG) and 3,4-disuccinyldianhydrogalactitol (DisuDAG) at maxima nonlethal single doses to tumor-bearing mice were studied." | 3.67 | Damages of DNA synthesis in normal and tumor cells with sugar alcohol derivatives. ( Elekes, I; Gorbacheva, LB; Otvös, L; Sokolova, IS, 1984) |
"Two drugs known to inhibit the action of calmodulin, prochlorperazine offP) and N-(6-aminohexyl)-5-chloro-1-napthalene sulfonamide (W7), were investigated for their ability to control cell proliferation in murine B16 melanoma cells in culture." | 3.67 | Effects of extracellular calmodulin and calmodulin antagonists on B16 melanoma cell growth. ( Bleehen, SS; Mac Neil, S; Senior, HJ; Tomlinson, S; Walker, SW, 1984) |
"In the human melanoma cell line MM127 , the melphalan survival curve was linear and exhibited reciprocity with respect to concentration and treatment time." | 3.67 | Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. ( Parsons, PG, 1984) |
"The effect of tamoxifen on the growth of malignant melanoma was investigated using human cell lines and single-cell suspensions prepared from patients' tumours cultured in soft agar." | 3.67 | The effect of tamoxifen on the growth of human malignant melanoma in vitro. ( De Young, NJ; Gill, PG; Horsfall, DJ; Keightley, DD; Thompson, A, 1984) |
" Explants of X56, an adenocarcinoma of colon, and HXG2, an amelanotic melanoma, both maintained by serial transplantation in athymic mice, were sequentially incubated in vitro with 14C-thymidine, one of several concentrations of adriamycin, and then 3H-thymidine." | 3.67 | Adriamycin response of two human tumor xenografts using a double-radiolabel organ culture method. ( Sullivan, JL; Sullivan, LG, 1989) |
"The cytotoxic effect of cis-diamminedichloroplatinum(II) (cis-DDP), as measured by a dye exclusion assay was much more pronounced in bone marrow cells and phytohemagglutinin (PHA)-stimulated lymphocytes than in a human melanoma cell line." | 3.67 | Cis-diamminedichloroplatinum(II) toxicity in human melanoma cells and lymphocytes as related to cellular platinum accumulation, DNA cross-linking and inhibition of DNA synthesis. ( Hansson, J; Lewensohn, R; Ringborg, U, 1988) |
"The anti-tumour methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide (MTIC) increased the thymidine and deoxycytidine pools but not the deoxyguanosine pool in human melanoma cells." | 3.67 | Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells. ( Hayward, IP; Parsons, PG, 1984) |
"Chloroquinoxaline sulfonamide (CQS), a chlorinated derivative of sulfaquinoxaline (SQ), inhibited proliferation of murine B16 melanoma cells, but only when relatively high drug concentrations (1 mM) were used." | 3.67 | Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells. ( Branda, RF; McCormack, JJ; Perlmutter, CA, 1988) |
"The 3H-thymidine labeling index (LI) was determined on 178 lesions, four of which were primary, from 129 patients with malignant melanoma." | 3.67 | Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin. ( Attili, A; Clemente, C; Costa, A; Grignolio, E; Silvestrini, R; Testori, A, 1987) |
"Sodium cyanate injected IP at a dose level of 200 or 250 mg/kg caused a 90% or greater inhibition of the incorporation of [3H]thymidine into DNA of B16 melanoma transplanted SC in mice." | 3.67 | Effects of sodium cyanate in mice bearing B16 melanoma. ( Carpenter, L; Hill, GJ; Hill, HZ; Lea, MA; Luke, A; Martinson, CF; Velazquez, O, 1986) |
"The growth inhibitory effects, the reduction of [3H]-TdR incorporation and the perturbation of the cell cycle induced by the new agent mitozolomide on the M14 human melanoma cell line and on the SW626 human ovarian cancer cell line were compared to those produced by BCNU." | 3.67 | Mitozolomide activity on human cancer cells in vitro. ( D'Incalci, M; Erba, E; Landoni, F; Lorico, A; Mangioni, C; Morasca, L; Pepe, S; Ubezio, P, 1986) |
"0 microCi/ml (methyl-3H)thymidine (3H-TdR) the growth rate of 6 human melanoma lines and 1 subline progressively slowed then stopped, a change that was accompanied by loss of reproductive viability as assessed by colony formation in agar, but unaccompanied by a comparable inhibition of thymidine incorporation." | 3.66 | Tritiated-thymidine-induced increased DNA content and irreversible differentiation in a human melanoma cell line. ( Sheridan, JW; Simmons, RJ, 1981) |
"The chemotherapeutic activity of thymidine (dThd) was tested against four human tumor xenografts growing in nude mice, including a melanoma, an oat cell carcinoma of the lung, a colon carcinoma, and a breast carcinoma." | 3.66 | Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice. ( Howell, SB; Jenkins, RS; Streifel, J, 1979) |
" implanted B-16 melanomas as well as of human melanomas have been incubated for 5 h with (H3) Uridine and (H3) Thymidine in the presence of different chemotherapeutical agents, whose concentration was equivalent to the tenfold therapeutical daily dose in men." | 3.66 | [In vitro and in vivo sensitivity of animal and human melanomas to various chemotherapeutical agents]. ( Rothmann, D; Schneider, O; Schussmann, M; Wiskemann, A, 1978) |
"3,4-Dihydroxybenzylamine (DHBA), a dopamine analog, was much less toxic than dopamine when tested against the B16 melanoma in vivo and in vitro." | 3.66 | 3,4-Dihydroxybenzylamine: a dopamine analog with enhanced antitumor activity against B16 melanoma. ( Wick, MM, 1979) |
"Cultured human malignant melanoma cells, when added to normal human lymphocytes stimulated to proliferate by mitogen or antigen, were found to inhibit the uptake of 3H-thymidine (3H-T) by the lymphocytes." | 3.65 | Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes. ( Dent, PB; Liao, SK; Lui, VK, 1977) |
"Single doses of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea caused transient suppression of [3H]thymidine incorporation into DNA in bone marrow and gastrointestinal mucosa and more prolonged inhibition of such incorporation in B16 melanoma." | 3.65 | Inhibition and recovery of DNA synthesis in host tissues and sensitive and resistant B16 melanoma after 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, a predictor of therapeutic efficacy. ( Brereton, HD; Bryant, TL; Young, RC, 1975) |
"The effect of thymidine (TdR) on the growth of a human melanoma transplanted in nude mice has been studied." | 3.65 | Effect of excess thymidine on the growth of human melanoma cells transplanted in thymus deficient nude mice. ( Giovanella, BC; Lee, SS; Stehlin, JS, 1977) |
"When cells of a Syrian hamster melanoma were grown in increasing concentrations of bromodeoxyuridine (BrdU), lines of mutant cells able to grow well at high concentrations of BrdU were isolated." | 3.65 | Bromodeoxyuridine dependence--a new mutation in mammalian cells. ( Bick, MD; Davidson, RL, 1973) |
"Tumorigenicity of mouse melanoma cells is reduced or lost upon growth in vitro in 1 to 3 mug/ml of 5-bromodeoxyuridine (BUdR)." | 3.65 | Suppression of malignancy and differentiation in melanotic melanoma cells. ( Bruce, SA; Silagi, S, 1970) |
"Fusarochromanone has been shown to have both stimulatory and inhibitory effects on various mammalian cells, depending on the concentration used." | 1.34 | Inhibitory effects of fusarochromanone on melanoma growth. ( Culberson, C; Dréau, D; Foster, M; Hogg, M; Nunes, P; Wuthier, RE, 2007) |
"Malignant melanoma is a cancer whose incidence is rising rapidly, but the mechanism by which normal melanocytes become malignant in vivo is still little understood." | 1.31 | Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling. ( Geissinger, E; Schartl, M; Troppmair, J; Weisser, C; Wellbrock, C, 2002) |
" Dose-response curves were determined using a 5-day incubation period and 6-h terminal [3H]thymidine-labelling period." | 1.29 | Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays. ( Baguley, BC; Finlay, GJ; Holdaway, KM; Marshall, ES; Matthews, JH; Nixon, J; Shaw, JH; Tumewu, P, 1994) |
"In the search for cytokines whose antiproliferative action could be enhanced by combination with dipyridamole, 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrim idine, the combination of tumor necrosis factor-alpha (TNF-alpha) with this agent was evaluated in various human tumor cell lines." | 1.29 | Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines. ( Kojima, T; Sekiya, S; Sugano, I; Suzuki, N; Takakubo, Y; Yamamori, H, 1995) |
"Fotemustine (S 10036) is a new anti-tumor nitrosourea characterized by a phosphonoalanine carrier group coupled to the nitrosourea moiety, which potentially increases the cellular penetration of the drug." | 1.28 | In vitro chemosensitivity testing of Fotemustine (S 10036), a new antitumor nitrosourea. ( Bizzari, JP; Deloffre, P; Etienne, MC; Fischel, JL; Formento, P; Frenay, M; Gioanni, J; Milano, G, 1990) |
"[3H]Thymidine uptake was inhibited by 12%, but no inhibition was detected in [3H]thymidine incorporation." | 1.27 | High-dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line. ( DiSorbo, DM; Nathanson, L, 1983) |
"Treatment with indomethacin blocks prostaglandin synthesis and induces thermosensitivity." | 1.27 | Natural thermal resistance of human tumor cells and the role of prostaglandin. ( Hildebrand-Zanki, S; Kern, DH; Morton, DL; Roe, DJ; Storm, FK; Worth, GD, 1983) |
" The method allows large numbers of replicate samples so that quantitation of dose-response relationships is simple and statistically robust, and simultaneous monitoring of cell attachment and growth within the same sample is routine." | 1.27 | Use of growth-attachment correlation plots to analyse human melanoma cell dependency on 2-oxocarboxylates and serum. ( Ellem, KA; Kay, GF, 1985) |
"Thymidine incorporation was measured at frequent intervals after heat shock to determine the time of onset of the next DNA synthetic period." | 1.27 | Delay in entry into S phase after heat shock. ( Dewey, DL; Holden, JL, 1984) |
"Fourteen of 20 lung cancer patients responded to lung cancer antigen, whereas only 11 of 41 patients with other tumors and 3 of 19 normal subjects reacted." | 1.26 | A rapid assay for stimulation of human lymphocytes by tumor-associated antigens. ( Grimm, EA; Morton, DL; Roth, JA, 1976) |
"The cytotoxic action of lymphocytes on cancer cells in vitro indicates sensitization of the patient against his own tumor." | 1.25 | [The lymphocyte cytotoxicity test in tumor immunology (author's transl)]. ( Pees, HW, 1975) |
"More precise definition of the cytokinetic parameters of human tumor growth will clearly help both in predicting the outcome of disease in individual patients and in planning the dosage schedules of single chemotherapeutic agents and combinations of agents to achieve optimal results." | 1.25 | Growth kinetics of solid tumors. Implications for chemotherapy. ( Curby, WA; Rosenoer, VM, 1975) |
"Cycloheximide treatment (1-5 microg/ml) of heterokaryons during the preceding lag period inhibits the initiation of macrophage DNA synthesis, in a reversible fashion." | 1.25 | Macrophage-melanoma cell heterokaryons. 3. The activation of macrophage DNA synthesis. Studies with inhibitors of protein synthesis and with synchronized melanoma cells. ( Cohn, Z; Gordon, S, 1971) |
"Serum from cancer patients impaired the response of normal lymphocytes." | 1.25 | The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients. ( Kumar, S; Taylor, G, 1973) |
"The cytokinetics of subcutaneous metastases in five patients with melanoma was studied." | 1.25 | Cell proliferation in human melanoma. ( Frei, E; Luce, JK; Shirakawa, S; Tannock, I, 1970) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 148 (75.90) | 18.7374 |
1990's | 31 (15.90) | 18.2507 |
2000's | 13 (6.67) | 29.6817 |
2010's | 3 (1.54) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Miran, T | 1 |
Vogg, ATJ | 1 |
El Moussaoui, L | 1 |
Kaiser, HJ | 1 |
Drude, N | 1 |
von Felbert, V | 1 |
Mottaghy, FM | 1 |
Morgenroth, A | 1 |
Gluck, I | 1 |
Simon, AJ | 1 |
Catane, R | 1 |
Pfeffer, R | 1 |
Schachter, J | 1 |
Rechavi, G | 1 |
Bar, J | 1 |
Tseng, JR | 1 |
Stuart, D | 1 |
Aardalen, K | 1 |
Kaplan, A | 1 |
Aziz, N | 1 |
Hughes, NP | 1 |
Gambhir, SS | 1 |
Goukassian, DA | 1 |
Sharov, A | 1 |
Rhodes, J | 1 |
Coleman, C | 1 |
Eller, MS | 1 |
Sharova, T | 1 |
Bhawan, J | 1 |
Gilchrest, BA | 1 |
Zelvyte, I | 1 |
Sjögren, HO | 1 |
Janciauskiene, S | 1 |
MARAINI, G | 1 |
FRANGUELLI, R | 1 |
POLACK, FM | 1 |
Tang, CH | 1 |
Grimm, EA | 2 |
Mahabir, S | 1 |
Frenkel, K | 1 |
Brady, MS | 1 |
Coit, D | 1 |
Leibes, L | 1 |
Karkoszka, J | 1 |
Berwick, M | 1 |
Antony, S | 1 |
Agama, KK | 1 |
Miao, ZH | 1 |
Hollingshead, M | 1 |
Holbeck, SL | 1 |
Wright, MH | 1 |
Varticovski, L | 1 |
Nagarajan, M | 1 |
Morrell, A | 1 |
Cushman, M | 1 |
Pommier, Y | 1 |
Pourpak, A | 1 |
Dorr, RT | 1 |
Meyers, RO | 1 |
Powell, MB | 1 |
Stratton, SP | 1 |
Dréau, D | 1 |
Foster, M | 1 |
Hogg, M | 1 |
Culberson, C | 1 |
Nunes, P | 1 |
Wuthier, RE | 1 |
Stragand, JJ | 1 |
Drewinko, B | 2 |
Barlogie, B | 1 |
Papadopoulous, N | 1 |
White, RA | 1 |
Parsons, PG | 4 |
Musk, P | 1 |
Goss, PD | 1 |
Leah, J | 1 |
Hakim, AA | 2 |
Leyva, A | 2 |
Appel, H | 2 |
Pinedo, HM | 2 |
Hill, HZ | 2 |
Hill, GJ | 2 |
Sokolova, IS | 1 |
Elekes, I | 1 |
Otvös, L | 1 |
Gorbacheva, LB | 1 |
Hayward, IP | 1 |
Gill, PG | 1 |
De Young, NJ | 1 |
Thompson, A | 1 |
Keightley, DD | 1 |
Horsfall, DJ | 1 |
Vercammen-Grandjean, A | 1 |
Arnould, R | 1 |
Libert, A | 2 |
Ewalenko, P | 1 |
Lejeune, F | 1 |
Storm, FK | 1 |
Roe, DJ | 1 |
Hildebrand-Zanki, S | 1 |
Worth, GD | 1 |
Morton, DL | 6 |
Kern, DH | 2 |
DiSorbo, DM | 4 |
Nathanson, L | 4 |
Lockshin, A | 2 |
Mendoza, JT | 1 |
Giovanella, BC | 4 |
Stehlin, JS | 4 |
Dewey, DL | 1 |
Holden, JL | 1 |
Mac Neil, S | 1 |
Walker, SW | 1 |
Senior, HJ | 1 |
Bleehen, SS | 1 |
Tomlinson, S | 1 |
McNulty, B | 1 |
Furuse, T | 1 |
Kasuga, T | 1 |
Lönn, U | 6 |
Dippenaar, N | 1 |
Booyens, J | 1 |
Fabbri, D | 1 |
Katzeff, IE | 1 |
Sheridan, JW | 3 |
Simmons, RJ | 2 |
Bishop, CJ | 1 |
Lönn, S | 4 |
Suzuki, N | 1 |
Sekiya, S | 1 |
Sugano, I | 1 |
Kojima, T | 1 |
Yamamori, H | 1 |
Takakubo, Y | 1 |
Richardson, DR | 1 |
Neumannova, V | 1 |
Ponka, P | 1 |
Roby, P | 1 |
Page, M | 1 |
Piérard-Franchimont, C | 1 |
Piérard, GE | 1 |
Marshall, ES | 2 |
Matthews, JH | 1 |
Shaw, JH | 1 |
Nixon, J | 1 |
Tumewu, P | 1 |
Finlay, GJ | 1 |
Holdaway, KM | 2 |
Baguley, BC | 2 |
Smit, NP | 1 |
Latter, AJ | 1 |
Naish-Byfield, S | 1 |
Westerhof, W | 1 |
Pavel, S | 1 |
Riley, PA | 1 |
Kirshenbaum, MR | 1 |
Chen, SF | 1 |
Behrens, CH | 1 |
Papp, LM | 1 |
Stafford, MM | 1 |
Sun, JH | 1 |
Behrens, DL | 1 |
Fredericks, JR | 1 |
Polkus, ST | 1 |
Sipple, P | 1 |
Fuchsberger, N | 1 |
Kubes, M | 1 |
Kontsek, P | 1 |
Borecký, L | 1 |
Hornák, M | 1 |
Godál, A | 1 |
Svec, J | 1 |
Pettersson, OA | 1 |
Olsson, P | 1 |
Lindström, P | 1 |
Sjöberg, S | 1 |
Carlsson, J | 1 |
Süli-Vargha, H | 1 |
Ghanem, G | 1 |
Morandini, R | 1 |
Botyánszki, J | 1 |
Medzihradszky, K | 1 |
Takeyama, H | 1 |
Hoon, DS | 1 |
Saxton, RE | 1 |
Irie, RF | 1 |
Muthukkumar, S | 1 |
Sells, SF | 1 |
Crist, SA | 1 |
Rangnekar, VM | 2 |
Kikuchi, K | 1 |
Nakagawa, H | 1 |
Kadono, T | 1 |
Etoh, T | 1 |
Byers, HR | 1 |
Mihm, MC | 1 |
Tamaki, K | 1 |
Clavo, AC | 1 |
Wahl, RL | 1 |
Nakayama, J | 1 |
Nakao, T | 1 |
Mashino, T | 1 |
Nagae, S | 1 |
Hori, Y | 1 |
Mayumi, H | 1 |
Tominaga, R | 1 |
Yasui, H | 1 |
Matsuda, K | 1 |
Takahashi, S | 1 |
Chakraborty, AK | 1 |
Sodi, S | 1 |
Rachkovsky, M | 1 |
Kolesnikova, N | 1 |
Platt, JT | 1 |
Bolognia, JL | 1 |
Pawelek, JM | 1 |
Abbas Rizvi, SM | 1 |
Sarkar, S | 1 |
Goozee, G | 1 |
Allen, BJ | 1 |
Parmar, J | 1 |
Charters, GA | 1 |
Shelling, AN | 1 |
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Thomas-Tikhonenko, A | 1 |
Wellbrock, C | 1 |
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Geissinger, E | 1 |
Troppmair, J | 1 |
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Wayss, K | 4 |
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Cheng, FM | 1 |
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Glass, J | 1 |
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Mezzanotte, G | 1 |
Vaglini, M | 1 |
Grignolio, E | 2 |
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Cascinelli, N | 1 |
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Onozaki, K | 1 |
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Milano, G | 1 |
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Nylen, U | 2 |
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McGarvey, TW | 1 |
Persky, B | 1 |
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Perlmutter, CA | 1 |
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Chawla, RK | 1 |
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Carpenter, L | 1 |
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Ubezio, P | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Mature Dendritic Cell Vaccination Against gp100 in Patients With Advanced Melanoma[NCT00683670] | Phase 1 | 17 participants (Actual) | Interventional | 2008-08-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for thymidine and Melanoma
Article | Year |
---|---|
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells.
Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; De | 1985 |
Evidence for immune reactivity against neoplasms.
Topics: Animals; Antibodies; Antibody Formation; Antigens; Antigens, Neoplasm; Antigens, Viral; Binding Site | 1971 |
3 trials available for thymidine and Melanoma
Article | Year |
---|---|
Randomized, placebo-controlled pilot trial of the effects of alpha-tocopherol supplementation on levels of autoantibodies against 5-hydroxymethyl-2-deoxyuridine in melanoma patients.
Topics: alpha-Tocopherol; Antineoplastic Agents; Antioxidants; Autoantibodies; Dietary Supplements; DNA Dama | 2004 |
Kinetics of immunological parameters in patients with malignant melanoma treated with hyperthermic isolated limb perfusion.
Topics: Adult; Aged; Extremities; Female; Humans; Hyperthermia, Induced; Intercellular Adhesion Molecule-1; | 1997 |
Clinical and biochemical studies of high-dose intermittent therapy of solid tumors with hydroxyurea (NSC-32065).
Topics: Adult; Aged; Blood Urea Nitrogen; Chondrosarcoma; Clinical Trials as Topic; Depression, Chemical; DN | 1970 |
190 other studies available for thymidine and Melanoma
Article | Year |
---|---|
Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma.
Topics: Animals; Antineoplastic Agents; Biomarkers; Biosynthetic Pathways; Cell Cycle Checkpoints; Cell Line | 2017 |
Germline analysis of thymidine/guanidine polymorphism at position 309 of the Mdm2 promoter in malignant melanoma patients.
Topics: Adult; Aged; Aging; DNA; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germ C | 2009 |
Use of DNA microarray and small animal positron emission tomography in preclinical drug evaluation of RAF265, a novel B-Raf/VEGFR-2 inhibitor.
Topics: Animals; Biomarkers, Tumor; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Fluorodeoxygluc | 2011 |
Topical application of thymidine dinucleotide to newborn mice reduces and delays development of UV-induced melanomas.
Topics: Administration, Topical; Animals; Animals, Newborn; Melanoma; Mice; Mice, Knockout; Neoplasms, Radia | 2012 |
Effects of native and cleaved forms of alpha1-antitrypsin on ME 1477 tumor cell functional activity.
Topics: alpha 1-Antitrypsin; Enzyme Activation; Humans; Male; Melanoma; Metalloendopeptidases; Middle Aged; | 2002 |
[RADIOAUTOGRAPHICAL STUDY OF THE PROLIFERATIVE ACTIVITY OF THE VARIOUS TYPES OF CELLULAR ELEMENTS IN A MELANOTIC SARCOMA OF THE IRIS AND CILIARY BODY].
Topics: Autoradiography; Ciliary Body; DNA; DNA, Neoplasm; Eye Neoplasms; Humans; Iris; Melanoma; Metabolism | 1963 |
INCORPORATION OF TRITIATED THYMIDINE BY OCULAR TUMORS IN VITRO.
Topics: Cell Division; Eye Neoplasms; In Vitro Techniques; Melanoma; Metabolism; Research Design; Retinoblas | 1965 |
Depletion of endogenous nitric oxide enhances cisplatin-induced apoptosis in a p53-dependent manner in melanoma cell lines.
Topics: Apoptosis; Cell Cycle; Cell Division; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA | 2004 |
Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity.
Topics: Animals; Antineoplastic Agents; Catalysis; Cell Death; DNA; DNA Damage; DNA Topoisomerases, Type II; | 2006 |
Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line.
Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytosol; | 2007 |
Inhibitory effects of fusarochromanone on melanoma growth.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Chromones; Humans; Immunohis | 2007 |
Serial analysis of melanoma growth kinetics in a patient receiving bleomycin and procarbazine therapy: comparison of tumor volume, flow cytometry, and thymidine labeling techniques.
Topics: Autoradiography; Bleomycin; Cell Division; DNA, Neoplasm; Female; Flow Cytometry; Humans; Melanoma; | 1982 |
Effects of calcium depletion on human cells in vitro and the anomalous behavior of the human melanoma cell line MM170.
Topics: Calcium; Cell Division; Cell Line; Cell Membrane; DNA; Egtazic Acid; Ethylene Glycols; Humans; Inter | 1983 |
Correlation between immunosuppressive agents from media of human malignant melanoma cell cultures and from human serum.
Topics: Animals; Blood; Cell Line; Cells, Cultured; Chemical Fractionation; Chromatography, Gel; Culture Med | 1981 |
Diverse deoxyribonucleotide profiles in cultured human cells with differential sensitivity to thymidine.
Topics: B-Lymphocytes; Cell Line; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides; | 1984 |
In vitro activation of cyclophosphamide for an in vitro chemosensitivity assay.
Topics: Aminopyrine N-Demethylase; Animals; Biotransformation; Cell Survival; Cyclophosphamide; Dose-Respons | 1984 |
Damages of DNA synthesis in normal and tumor cells with sugar alcohol derivatives.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Line; Dianhydrogalactitol; DNA; Injections, Intrap | 1984 |
Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells.
Topics: Alkylating Agents; Antineoplastic Agents; Cell Line; Dacarbazine; Deoxycytidine; Deoxyguanosine; Gen | 1984 |
The effect of tamoxifen on the growth of human malignant melanoma in vitro.
Topics: Cell Count; Cell Division; Cell Line; Humans; Melanoma; Receptors, Estrogen; Receptors, Progesterone | 1984 |
Production of the effector molecule thymidine by human lung alveolar macrophages.
Topics: Animals; Ascitic Fluid; Biological Assay; Cells, Cultured; Chromatography, Thin Layer; Humans; Macro | 1984 |
Natural thermal resistance of human tumor cells and the role of prostaglandin.
Topics: Cell Line; Cell Membrane; Dinoprostone; Drug Evaluation; Hot Temperature; Humans; Indomethacin; Mela | 1983 |
Thymidine sensitivity and deoxynucleotide pools of human lymphoid and melanoma cells in vitro.
Topics: Cell Line; Chromatography, High Pressure Liquid; Deoxyribonucleotides; Humans; Kinetics; Leukemia, L | 1984 |
High-dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line.
Topics: Cell Division; Cells, Cultured; Glucose; Humans; In Vitro Techniques; Leucine; Male; Melanoma; Pyrid | 1983 |
Cytotoxic and biochemical effects of thymidine and 3-deazauridine on human tumor cells.
Topics: 3-Deazauridine; Adrenal Gland Neoplasms; Cell Division; Cell Line; Cell Survival; Deoxyribonucleotid | 1984 |
Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines.
Topics: Caffeine; Cell Line; Cell Survival; Chlorambucil; DNA, Neoplasm; Drug Resistance; Drug Synergism; Ho | 1984 |
Delay in entry into S phase after heat shock.
Topics: Animals; Cell Line; DNA; Hot Temperature; Interphase; Melanoma; Mice; Thymidine; Time Factors | 1984 |
Effects of extracellular calmodulin and calmodulin antagonists on B16 melanoma cell growth.
Topics: Animals; Calmodulin; Cell Line; Cells, Cultured; Culture Media; DNA, Neoplasm; Dose-Response Relatio | 1984 |
In vitro growth inhibition of human malignant melanoma cells by glucocorticoids.
Topics: Cell Division; Cell Line; Glucocorticoids; Humans; Melanoma; Progesterone; Receptors, Glucocorticoid | 1983 |
Difference in 3H-thymidine incorporation after irradiation between murine B16 melanoma and squamous cell carcinoma in vivo.
Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Dose-Response Relationship, Radiation; | 1983 |
Effect of estradiol and degree of cell differentiation on human melanoma susceptibility to killing by monoclonal antibodies.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Comple | 1982 |
Detection of a 10 kb DNA replication intermediate in human melanoma cells.
Topics: Cells, Cultured; Centrifugation, Density Gradient; DNA; DNA Replication; DNA, Single-Stranded; Elect | 1982 |
Formation of a new population of DNA replication intermediates in X-irradiated human melanoma cells.
Topics: Cells, Cultured; DNA Replication; Humans; Melanoma; Neoplasms, Experimental; Thymidine | 1982 |
The reversibility of cancer: evidence that malignancy in melanoma cells is gamma-linolenic acid deficiency-dependent.
Topics: Animals; Cattle; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relatio | 1982 |
Tritiated-thymidine-induced increased DNA content and irreversible differentiation in a human melanoma cell line.
Topics: Cell Count; Cell Differentiation; Cell Line; DNA, Neoplasm; Humans; Melanoma; Mitotic Index; Thymidi | 1981 |
Biophysical and morphological correlates of kinetic change and death in a starved human melanoma cell line.
Topics: Biophysical Phenomena; Biophysics; Cell Line; Cell Separation; Cell Survival; Humans; Kinetics; Mela | 1981 |
Melphalan prevents the formation of double-stranded DNA replication intermediates in human malignant melanoma cells.
Topics: Cell Division; Cells, Cultured; DNA Replication; Humans; Kinetics; Melanoma; Melphalan; Thymidine; T | 1981 |
Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines.
Topics: Amino Acids; Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carbon Rad | 1995 |
Nitrogen monoxide decreases iron uptake from transferrin but does not mobilise iron from prelabelled neoplastic cells.
Topics: Animals; Cell Line; Cyclic GMP; Humans; Iodine Radioisotopes; Iron; Iron Radioisotopes; Melanoma; Mi | 1995 |
Cell-binding and growth-stimulating activities of the C-terminal part of human MGSA/Gro alpha.
Topics: Amino Acid Sequence; Binding Sites; Cell Division; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chem | 1995 |
Karyometry of primary and metastatic malignant melanoma. A correlation with cell proliferation.
Topics: Cell Division; Cell Nucleus; Humans; Karyometry; Melanoma; Prognosis; Skin Neoplasms; Thymidine | 1994 |
Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays.
Topics: Adult; Aged; Cell Survival; Dose-Response Relationship, Radiation; Female; Humans; Male; Melanoma; M | 1994 |
Catechol-O-methyltransferase as a target for melanoma destruction?
Topics: Anisoles; Antineoplastic Agents; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibito | 1994 |
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro.
Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Colonic | 1994 |
In vitro antiproliferative effect of interferon alpha in solid tumors: a potential predictive test.
Topics: Adult; Aged; Aged, 80 and over; Cell Division; DNA, Neoplasm; Female; Humans; Interferon-alpha; Kidn | 1993 |
Penetration and binding of L- and D-carboranylalanine in human melanoma spheroids.
Topics: Boron Compounds; Boron Neutron Capture Therapy; Cell Aggregation; Cell Cycle; Humans; Melanoma; Phen | 1993 |
Receptor binding and cytotoxicity studies with melanotropin fragments containing melphalan.
Topics: alpha-MSH; Amino Acid Sequence; Cell Division; Fibroblasts; Humans; Kinetics; Melanoma; Melphalan; M | 1993 |
Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine.
Topics: Animals; Cell Division; Cysteine; Dose-Response Relationship, Drug; Gangliosides; Humans; Melanins; | 1993 |
Interleukin-1 induces growth arrest by hypophosphorylation of the retinoblastoma susceptibility gene product RB.
Topics: Antigens, Polyomavirus Transforming; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Divisio | 1996 |
Decreased ET(B) receptor expression in human metastatic melanoma cells.
Topics: Amino Acid Sequence; Cell Line; DNA, Neoplasm; Endothelins; Gene Expression; Humans; Kinetics; Melan | 1996 |
Effects of hypoxia on the uptake of tritiated thymidine, L-leucine, L-methionine and FDG in cultured cancer cells.
Topics: Cell Hypoxia; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; In Vitro Techniques; Leucine; Me | 1996 |
A spontaneous murine melanoma lung metastasis comprised of host x tumor hybrids.
Topics: Aminopterin; Animals; Anti-Bacterial Agents; Antigens, CD; Antineoplastic Combined Chemotherapy Prot | 2000 |
Radioimmunoconjugates for targeted alpha therapy of malignant melanoma.
Topics: Antibodies, Monoclonal; Bismuth; Chelating Agents; DNA, Neoplasm; Humans; Immunoconjugates; Isothioc | 2000 |
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines.
Topics: Adult; Aged; Aged, 80 and over; Cell Cycle; DNA, Neoplasm; Female; Flow Cytometry; Genes, p53; Human | 2000 |
Intratumoral delivery of an interferon gamma retrovirus-producing cells inhibits growth of a murine melanoma by a non-immune mechanism.
Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Enzyme-Linked Immunosorbent | 2001 |
Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling.
Topics: Cell Cycle Proteins; Cell Differentiation; Colforsin; Cyclic AMP; DNA Primers; DNA, Neoplasm; Dual S | 2002 |
Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues.
Topics: Adenoma; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blotting, Western; Breast Neoplasms; | 2002 |
[The lymphocyte cytotoxicity test in tumor immunology (author's transl)].
Topics: Animals; Antigens, Neoplasm; B-Lymphocytes; Cells, Cultured; Chromium Radioisotopes; Culture Media; | 1975 |
[Correlation of in vitro testing and therapeutical results in animal transplanted tumors after cytostatic treatment].
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bleomycin; Carcinoma 256, Walker; Cricetinae; Dactin | 1975 |
The use of viable frozen lymphocytes for studies in human tumor immunology.
Topics: Adult; Blood Preservation; Cell Separation; Cell Survival; Cells, Cultured; Concanavalin A; Cytotoxi | 1975 |
Sensitivity tests of tumors to cytostatic agents. I. Comparative investigations on transplanted tumors in vivo and in vitro.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Cricetinae; Da | 1975 |
Maturation and differentiation of B16 melanoma cells induced by theophylline treatment.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Clone Cells; Cyclic AMP; DNA, Neoplas | 1975 |
3,4-Dihydroxybenzylamine: a dopamine analog with enhanced antitumor activity against B16 melanoma.
Topics: Animals; Cells, Cultured; Dopamine; Melanoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; T | 1979 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru | 1977 |
Regression of human tumors established in nude mice after continuous infusion of thymidine.
Topics: Animals; Breast Neoplasms; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Melanoma; Mi | 1979 |
Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Humans; Lung Neopl | 1979 |
Specific protection against the cytotoxicity of a new class of nitrosoureas by pyrimidine deoxyribonucleosides.
Topics: Animals; Cell Survival; Cells, Cultured; Deoxyribonucleosides; Leukemia L1210; Melanoma; Mice; Neopl | 1979 |
Novel phenotypes arising from selection of hamster melanoma cells for resistance to BUdR.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Clone Cells; Cricetinae; DNA, Neoplasm; Drug R | 1977 |
[In vitro and in vivo sensitivity of animal and human melanomas to various chemotherapeutical agents].
Topics: Animals; Antineoplastic Agents; Cricetinae; Drug Resistance; Humans; In Vitro Techniques; Melanoma; | 1978 |
Inhibition of [3H]TdR and [3H]CdR incorporation in an established human lymphoma cell line by trypsin treatment.
Topics: Animals; Cell Line; Cell Separation; Deoxycytidine; DNA, Neoplasm; HeLa Cells; Humans; Lymphoma, Non | 1978 |
Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes.
Topics: Antigens, Neoplasm; Cell Line; DNA; Humans; Immunity, Cellular; In Vitro Techniques; Lectins; Lympho | 1977 |
Dopamine: a novel antitumor agent active against B-16 melanoma in vivo.
Topics: Animals; Antineoplastic Agents; Dopamine; Leucine; Melanoma; Mice; Neoplasms, Experimental; Thymidin | 1978 |
Characterisation of an inhibitor of thymidine uptake produced by cultured human melanoma cells.
Topics: Amino Acids; Cell Line; Humans; In Vitro Techniques; Kanamycin; Lymphocyte Activation; Lymphocytes; | 1978 |
Comparative effects on growth and tumorigenicity of mouse melanoma cells by thymidine and its analogs, 5-ethyl- and 5-bromodeoxyuridine.
Topics: Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Kinetics; M | 1977 |
Effect of excess thymidine on the growth of human melanoma cells transplanted in thymus deficient nude mice.
Topics: Animals; Cell Line; Female; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, | 1977 |
A rapid assay for stimulation of human lymphocytes by tumor-associated antigens.
Topics: Antigens, Neoplasm; Carcinoma; Female; Hemagglutination Tests; Hemocyanins; Humans; Leucine; Lung; L | 1976 |
A rapid in vitro labeling index method for predicting response of human solid tumors to chemotherapy.
Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Drug Evaluation; Female; Humans; In Vitro | 1976 |
[Autoradiographic study of pigmented murine melanoma].
Topics: Animals; Autoradiography; Melanoma; Mice; Mitosis; Neoplasm Transplantation; Neoplasms, Experimental | 1976 |
[In vitro study of peripheral blood with thymidine-3H in the diagnosis of melanoma of the skin].
Topics: Blood Cells; Humans; In Vitro Techniques; Melanoma; Skin Neoplasms; Thymidine | 1976 |
Kinetic aids to proper chemotherapeutic scheduling: labeled nucleoside incorporation studies in vivo.
Topics: Animals; Bone Marrow; Cell Survival; Cyclophosphamide; DNA, Neoplasm; Drug Administration Schedule; | 1976 |
Growth kinetics of solid tumors. Implications for chemotherapy.
Topics: Acute Disease; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Cul | 1975 |
In vitro tumor cell destruction by syngeneic mouse macrophoages: methods for assaying cytotoxicity.
Topics: Animals; Cell Count; Cells, Cultured; Culture Techniques; Cytotoxicity Tests, Immunologic; Embryo, M | 1975 |
Inhibition and recovery of DNA synthesis in host tissues and sensitive and resistant B16 melanoma after 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, a predictor of therapeutic efficacy.
Topics: Animals; Bone Marrow; Cell Division; Depression, Chemical; DNA; DNA, Neoplasm; Gastric Mucosa; Intes | 1975 |
Association of DNA with melanin granules.
Topics: Animals; Cytoplasmic Granules; DNA; Liver; Melanins; Melanoma; Mice; Mice, Inbred DBA; Neoplasms, Ex | 1975 |
The production of acidic polysaccharides by 5-bromodeoxyuridine-treated B16 mouse melanoma cells.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chondroitin; Depression, Chemical; DNA; Glucosamine; Gl | 1975 |
DNA repair and UV resistance in human melanoma.
Topics: Cells, Cultured; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Radiation Effects; Thymidine; Ultravio | 1975 |
Purification and analysis of growth regulating proteins secreted by a human melanoma cell line.
Topics: Amino Acid Sequence; Blotting, Western; Cell Division; Chromatography, Gel; Chromatography, High Pre | 1992 |
Biological and enzymatic features of human melanoma clones with different invasive potential.
Topics: Cell Adhesion; Cell Division; Clone Cells; Extracellular Matrix; gamma-Glutamyltransferase; Humans; | 1992 |
Interleukin-1-inducible tumor growth arrest is characterized by activation of cell type-specific "early" gene expression programs.
Topics: Cell Division; Cell Line; Dactinomycin; DNA Replication; DNA, Neoplasm; Gene Expression Regulation, | 1992 |
Interleukin-6 production by human melanoma cell lines.
Topics: Blotting, Northern; Cell Line; DNA Replication; Enzyme-Linked Immunosorbent Assay; Humans; Interleuk | 1992 |
Interleukin 6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression.
Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Growth Inhibitors; Humans; Inter | 1992 |
Murine monoclonal antibodies cytotoxic to human glioma cells in vitro.
Topics: Adult; Animals; Antibodies, Monoclonal; Astrocytes; Cytotoxicity Tests, Immunologic; Glioma; Humans; | 1992 |
Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells.
Topics: beta Carotene; Breast Neoplasms; Carotenoids; Cell Division; Cell Line; Colonic Neoplasms; DNA, Neop | 1992 |
Evaluation of the cytotoxic mechanisms mediated by the broad-spectrum antitumor alkaloid acronycine and selected semisynthetic derivatives.
Topics: Acronine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Cell Nucleus; Cel | 1992 |
Purification and characterization of recombinant melanoma growth stimulating activity.
Topics: Amino Acid Sequence; Animals; Biological Assay; Cell Division; Cell Line; Chemokine CXCL1; Chemokine | 1991 |
Diffusion and binding of monoclonal antibody TNT-1 in multicellular tumor spheroids.
Topics: Adenocarcinoma; Antibodies, Monoclonal; Autoradiography; Binding Sites, Antibody; Cell Division; Col | 1991 |
Abrogation of interferon-induced resistance to interferon-activated major histocompatibility complex-unrestricted killers by treatment of a melanoma cell line with 5-fluorouracil.
Topics: Adult; Cell Line; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Drug Resistance; Fluo | 1991 |
Effect of thymidine analogs on tyrosinase activity and mRNA accumulation in mouse melanoma cells.
Topics: Animals; Bromodeoxyuridine; Catechol Oxidase; Cell Line; Cell Transformation, Neoplastic; Floxuridin | 1990 |
Nerve growth factor (NGF) induces neuronal differentiation in neuroblastoma cells transfected with the NGF receptor cDNA.
Topics: Animals; Autoradiography; Cell Differentiation; Cell Line; DNA, Neoplasm; Flow Cytometry; Humans; Me | 1990 |
Cell kinetics: an independent prognostic variable in stage II melanoma of the skin.
Topics: Adult; Aged; Cell Division; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Prognosis | 1990 |
Antiproliferative effect of interleukin 1 (IL-1) on tumor cells: G0-G1 arrest of a human melanoma cell line by IL-1.
Topics: Cell Cycle; Cell Division; Cell Line; Clone Cells; Demecolcine; DNA Replication; Humans; Interleukin | 1990 |
In vitro chemosensitivity testing of Fotemustine (S 10036), a new antitumor nitrosourea.
Topics: Antineoplastic Agents; Carmustine; Cell Division; Cisplatin; Dacarbazine; Drug Screening Assays, Ant | 1990 |
Growth inhibitory effect of sodium azide in chemosensitivity assays.
Topics: Azides; Biopsy; Bleomycin; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Humans; | 1987 |
Altered formation of DNA in human cells treated with inhibitors of DNA topoisomerase II (etoposide and teniposide).
Topics: DNA Replication; DNA, Neoplasm; Etoposide; Humans; Kinetics; Melanoma; Podophyllotoxin; Teniposide; | 1989 |
Adriamycin response of two human tumor xenografts using a double-radiolabel organ culture method.
Topics: Adenocarcinoma; Animals; Carbon Radioisotopes; Colonic Neoplasms; Doxorubicin; Drug Screening Assays | 1989 |
Autocrine tumor cell growth-inhibiting activities from human malignant melanoma.
Topics: Biological Factors; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Growth In | 1989 |
Reduced DNA damage induced in human melanoma cells by dacarbazine in the presence of deoxyribonucleosides.
Topics: Dacarbazine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Damage; DNA, Neoplasm; Humans; Mela | 1989 |
The effects of retinoic acid and butyric acid on in vitro migration by murine B16a cells: a quantitative scanning electron microscopic study.
Topics: Animals; Butyrates; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Cytoskeleton; Melanom | 1989 |
Step-wise progression of mammalian 10-kb DNA replication intermediates to mature chromatin.
Topics: Benzamides; Cell Line; Chromatin; DNA Replication; DNA, Neoplasm; Endonucleases; Humans; Melanoma; P | 1988 |
Effect of triamcinolone acetonide on the growth of NEL-M1 human melanoma cells cultured in the presence and absence of growth stimulatory agents.
Topics: Cell Division; Cells, Cultured; Culture Media; ErbB Receptors; Growth Substances; Hormones; Humans; | 1986 |
Cis-diamminedichloroplatinum(II) toxicity in human melanoma cells and lymphocytes as related to cellular platinum accumulation, DNA cross-linking and inhibition of DNA synthesis.
Topics: Cell Line; Cell Survival; Cisplatin; DNA Replication; Humans; Hydrogen-Ion Concentration; Lymphocyte | 1988 |
Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells.
Topics: Animals; Cell Division; Cell Line; Chromatography, High Pressure Liquid; Deoxyuridine; DNA; Flow Cyt | 1988 |
Separation of melanoma growth stimulatory activity and human type-alpha transforming growth factor.
Topics: Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Culture Media; DNA Replication | 1987 |
An experimental model for studying the desmoplastic response to tumor invasion.
Topics: Animals; Cell Line; Collagen; Female; Fibrosis; Hydroxyproline; Melanoma; Mice; Mice, Inbred C57BL; | 1987 |
Preparation of a monoclonal antibody to a melanoma growth-stimulatory activity released into serum-free culture medium by Hs0294 malignant melanoma cells.
Topics: Animals; Antibodies, Monoclonal; Cell Division; Cell Line; Culture Media; Growth Substances; Humans; | 1987 |
Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin.
Topics: Adolescent; Adult; Aged; Cell Division; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metast | 1987 |
Infection of DBA/2 or C3H/HeJ mice by intraperitoneal injection of vaccinia virus elicits activated macrophages, cytolytic and cytostatic for S91-melanoma tumor cells.
Topics: Animals; Cytotoxicity, Immunologic; DNA, Neoplasm; Immunotherapy; Injections, Intraperitoneal; Kille | 1986 |
Biological characterization of an acid-sensitive growth factor from human platelets: role in the proliferation of human melanoma and bovine endothelial cells.
Topics: Animals; Aorta; Blood Platelets; Cattle; Cell Division; Cells, Cultured; Chromatography, Gel; Chroma | 1986 |
Effects of sodium cyanate in mice bearing B16 melanoma.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carmust | 1986 |
Mitozolomide activity on human cancer cells in vitro.
Topics: Aged; Antineoplastic Agents; Carmustine; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Fe | 1986 |
Suppression of DNA synthesis in NEL-M1 human melanoma cells by triamcinolone acetonide.
Topics: Cells, Cultured; Dihydroxyphenylalanine; DNA, Neoplasm; Humans; Melanoma; Receptors, Glucocorticoid; | 1985 |
Differential modulation by recombinant immune interferon of the expression and shedding of HLA antigens and melanoma associated antigens by a melanoma cell line resistant to the antiproliferative activity of immune interferon.
Topics: Animals; Antigens, Neoplasm; Cell Division; Cell Line; DNA; HLA Antigens; Humans; Interferon-gamma; | 1985 |
Antitumor activity and minimal toxicity of concentrated thymidine infused in nude mice.
Topics: Animals; Antineoplastic Agents; Male; Melanoma; Mice; Mice, Nude; Solubility; Thymidine; Thymine | 1985 |
Use of growth-attachment correlation plots to analyse human melanoma cell dependency on 2-oxocarboxylates and serum.
Topics: Carbon Radioisotopes; Carboxylic Acids; Cell Adhesion; Cell Division; Cell Line; DNA Replication; Hu | 1985 |
A novel approach to the study of kinetically changing cell populations.
Topics: Carbon Radioisotopes; Cell Cycle; Cell Division; Cell Line; DNA Replication; Humans; Kinetics; Melan | 1985 |
Glucocorticoid receptors and cell cycle progression in human melanoma cell lines.
Topics: Binding Sites; Cell Cycle; Cell Division; Cell Line; Colchicine; Dexamethasone; Flow Cytometry; Gluc | 1985 |
Macrophage-melanoma cell heterokaryons. 3. The activation of macrophage DNA synthesis. Studies with inhibitors of protein synthesis and with synchronized melanoma cells.
Topics: Animals; Anti-Bacterial Agents; Cell Fusion; Cell Nucleus; Cells, Cultured; Cyclohexanes; Cyclohexim | 1971 |
Bleomycin as a possible synchronizing agent for human tumor cells in vivo.
Topics: Antibiotics, Antineoplastic; Autoradiography; Biopsy; Bleomycin; Cell Division; Humans; Melanoma; Mi | 1973 |
Proceedings: Evaluation of immune status in tumor patients.
Topics: Adenocarcinoma; Alpha-Globulins; B-Lymphocytes; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; C | 1974 |
In vitro methods to complement in vivo approaches utilizing combinations of chemotherapy and immunotherapy.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Bleomycin; Carmustine; Cells, Cultured; Chickens | 1974 |
Detection in human melanoma cell lines of particles with some properties in common with RNA tumour viruses.
Topics: Biopsy; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cerebellar Neoplasms; DNA Nucl | 1974 |
[Observations on radioautographic methods of in vitro study of excised tissues using H3-thymidine].
Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Nucleus; Culture Techniques; Liver; Melanom | 1967 |
In vitro lymphocyte stimulation by a soluble antigen from malignant melanoma.
Topics: Adult; Aged; Antigens; Beta-Globulins; Blood Protein Electrophoresis; Cross Reactions; Electrophores | 1970 |
Inhibition of DNA and protein synthesis in melanocytes by a melanoma extract.
Topics: Animals; Carbon Radioisotopes; Catechol Oxidase; Cell Line; Cells, Cultured; Centrifugation, Density | 1974 |
Harding-Passey melanoma in the BALB-C mouse as a model for studying the interactions between host macrophages and tumor cells.
Topics: Acid Phosphatase; Animals; Ascitic Fluid; Catechol Oxidase; Female; Lymphocyte Activation; Lymphocyt | 1973 |
[On the significance of eosinophilic leukocytes in neurologic diseases].
Topics: Adult; Anaphylaxis; Brain Neoplasms; Child, Preschool; Diffuse Cerebral Sclerosis of Schilder; Eosin | 1969 |
A new model of growth regulation. Cell-specific inhibition of DNA-synthesis in HeLa-cells by endometrium extract.
Topics: Animals; Cricetinae; Depression, Chemical; DNA, Neoplasm; Endometrium; Female; Glycoproteins; Growth | 1969 |
[Nucleic acid and protein synthesis in hamster melanoma under the influence of drugs. I. In vivo studies of DNA synthesis in hamster melanoma].
Topics: Acridines; Animals; Cell Nucleus; Cricetinae; DNA, Neoplasm; Melanoma; Mitochondria; Neoplasm Protei | 1970 |
DNA synthesis in genetically determined melanomas of platyfish-swordtail hybrids.
Topics: Animals; Cyprinidae; DNA, Neoplasm; Fish Diseases; Hybridization, Genetic; Melanoma; Species Specifi | 1973 |
DNA replication and degradation in mammalian tissues. V. A series of slow-growing rat renal tumors and a variety of human cancers.
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Col | 1969 |
In vitro detection of cytotoxic cellular immunity against tumor-specific antigens by a radioisotopic technique.
Topics: Adenocarcinoma; Animals; Antigen-Antibody Reactions; Antigens; Antigens, Neoplasm; Autoradiography; | 1971 |
Lymphocyte blastogenic responses to cultured allogeneic tumor cells in vitro.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Count; Cells, Cultured; Female; Hu | 1972 |
Response of mouse melanoma cells to melanocyte stimulating hormone.
Topics: Animals; Catechol Oxidase; Cell Division; Cell Line; Cyclic AMP; DNA, Neoplasm; Melanocyte-Stimulati | 1974 |
In vitro determination of thymidine-3H labeling index in human solid tumors.
Topics: Autoradiography; Carcinoma, Small Cell; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm | 1974 |
Proceedings: Studies on a nonspecific and non-cytotoxic cytostatic factor produced by macrophages.
Topics: Animals; Cytotoxicity Tests, Immunologic; Female; Macrophages; Mammary Neoplasms, Experimental; Mela | 1974 |
Sensitisation of lymphocytes in vitro against human melanoma-associated antigens.
Topics: Antigens, Neoplasm; Cell Line; Cytotoxicity Tests, Immunologic; Humans; Lymphocyte Activation; Lymph | 1974 |
Bromodeoxyuridine dependence--a new mutation in mammalian cells.
Topics: Aminopterin; Animals; Bromodeoxyuridine; Cell Division; Cell Line; Centrifugation, Density Gradient; | 1973 |
Antigen solubilized from human solid tumours: lymphocyte stimulation and cutaneous delayed hypersensitivity.
Topics: Antigens, Neoplasm; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hodgkin Disease; Humans; | 1973 |
Total substitution of bromodeoxyuridine for thymidine in the DNA of a bromodeoxyuridine-dependent cell line.
Topics: Aminopterin; Animals; Autoradiography; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry; | 1974 |
Blastogenic response of normal lymphocytes to cultured lymphoid cells and non-lymphoid neoplastic cells.
Topics: Burkitt Lymphoma; Carcinoma; Cell Line; Cells, Cultured; Humans; Lymphocyte Activation; Lymphocytes; | 1972 |
[In vitro-determination of the cytostatic sensitivity of malignant tumours (author's transl)].
Topics: Antineoplastic Agents; Autoradiography; Carcinoma, Squamous Cell; Cyclophosphamide; Diethylstilbestr | 1973 |
[Comparative autoradiographic study on the stroma reaction in melanoma and basal cell epithelioma (author's transl)].
Topics: Autoradiography; Carcinoma, Basal Cell; Cytological Techniques; DNA, Neoplasm; Humans; Immunity, Cel | 1974 |
[Electron microscopy autoradiography of labelled host cells in mouse melanomas].
Topics: Animals; Autoradiography; Eosinophils; Epithelial Cells; Fibroblasts; Histiocytes; Injections, Intra | 1972 |
The in vivo cell kinetics of transplantable B16 mouse melanoma.
Topics: Animals; Cell Survival; DNA Replication; Kinetics; Male; Melanoma; Mice; Mice, Inbred C57BL; Mitosis | 1972 |
Lymphocyte reactivity in cancer patients: correlation with tumor histology and clinical stage.
Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Antilymphocyte Serum; Carcinoma; Carcinoma, Sq | 1973 |
Correlation of preoperative lymphocyte reactivity with the clinical course of cancer patients.
Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Follow-Up Studies; H | 1973 |
Effect of 5-bromodeoxyuridine (BUdR) on experimental metastasis.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Clone Cells; Dose-Response Relationship, Drug; Ido | 1973 |
Immunologic effects of BCG in patients with malignant melanoma: specific evidence for stimulation of the 'secondary' immune response.
Topics: Adult; Antibody Formation; BCG Vaccine; Candida; Complement System Proteins; Female; Humans; Hyperse | 1973 |
The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients.
Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lectins; Leukemia; Lymph | 1973 |
A cytokinetic model for heterogeneous mammalian cell populations. II. Tritiated thymidine studies: the per cent labeled mitosis (PLM) curve.
Topics: Age Factors; Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Count; Cell Survival; DNA; Emb | 1974 |
8-Azaguanine-resistant melanoma cells in vitro and in vivo.
Topics: Aminopterin; Animals; Azaguanine; Bromodeoxyuridine; Cell Division; Cell Fusion; Cell Line; Drug Res | 1974 |
Inhibition of melanogenesis with 5-bromodeoxyuridine treatment in a single period of DNA synthesis.
Topics: Bromodeoxyuridine; Cell Differentiation; Cell Division; Cells, Cultured; Depression, Chemical; DNA; | 1974 |
A study of cellular inflammatory reaction in human malignant melanoma, using in vitro-labelling techniques with h3-thymidine.
Topics: Biopsy; Connective Tissue Cells; DNA; Humans; Immunity, Active; Lymphocytes; Macrophages; Mast Cells | 1974 |
Immune surveillance and tumor dissemination: in vitro comparison of the B16 melanoma in primary and metastatic form.
Topics: Animals; Antigens, Neoplasm; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells; Cells, Cu | 1974 |
The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cytarabine; Dauno | 1974 |
Suppression of malignancy and differentiation in melanotic melanoma cells.
Topics: Animals; Bromodeoxyuridine; Clone Cells; Culture Techniques; Melanoma; Mice; Microscopy, Phase-Contr | 1970 |
Proliferation and differentiation of pigment cells in vitro.
Topics: Animals; Carbon Isotopes; Cell Count; Cell Differentiation; Cell Division; Cell Line; Chromatophores | 1970 |
[Autoradiographic investigation of whether the uptake of labeled thymidine under in vivo conditions is comparable to in vitro uptake by tissue samples].
Topics: Animals; Autoradiography; Biopsy; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Humans; In Vitro Techni | 1969 |
S91 mouse melanoma sublines following total in vitro versus alternate in vivo passages.
Topics: Animals; Autoradiography; Cell Line; Cells, Cultured; Dihydroxyphenylalanine; DNA, Neoplasm; Histocy | 1972 |
Metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in human and animal tumor tissue.
Topics: Amides; Animals; Antineoplastic Agents; Carbohydrates; Carbon Isotopes; Chromatography, Thin Layer; | 1972 |
In vivo synchrony of solid B16 melanoma by cytosine arabinoside, an inhibitor of DNA synthesis.
Topics: Animals; Autoradiography; Cell Division; Cell Survival; Cytarabine; DNA; Dose-Response Relationship, | 1972 |
Analysis of the cell kinetics of human solid tumors.
Topics: Adult; Aged; Biopsy; Bone Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Colo | 1971 |
Possible role of cell kinetics in prediction of the response to cancer therapy.
Topics: Animals; Antineoplastic Agents; Autoradiography; Drug Resistance; Humans; Mammary Neoplasms, Experim | 1971 |
Cell kinetic analysis of a human melanoma in vitro and in vivo-vitro.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Carbon Isotopes; Culture Techniques; DNA, Neo | 1971 |
Amino acids as stimulating agents of DNA replication in melanomas. I. Stimulation in explants.
Topics: Amino Acids; Animals; Autoradiography; Culture Techniques; DNA Replication; Enzyme Repression; Genes | 1969 |
Cell proliferation in human melanoma.
Topics: Adult; Aged; Autoradiography; Biopsy; Cell Division; DNA, Neoplasm; Female; Humans; Male; Melanoma; | 1970 |
Cytostasis of mouse and human monolayer cell cultures by normal, unstimulated lymphocytes.
Topics: Animals; Cell Count; Cell Line; Culture Techniques; Humans; L Cells; Lymph Nodes; Lymphocytes; Macro | 1970 |
DNA, RNA, and protein synthesis of pigment cells in culture.
Topics: Animals; Autoradiography; Chromatophores; Culture Techniques; DNA; Leucine; Melanins; Melanoma; Mice | 1970 |
[Microsurgical cell nucleus transplantation in mammalian cells].
Topics: Animals; Ascites; Autoradiography; Cell Division; Chromosomes; Culture Techniques; Histocompatibilit | 1970 |
Experience with a mixed lymphocyte-tumor reaction as a method of detecting antigenic differences between normal and neoplastic cells.
Topics: Animals; Antigens; Ascitic Fluid; Culture Techniques; Lymphocytes; Lymphoma; Melanoma; Mice; Radiati | 1970 |
[Specific cell functions of cell and tissue cultures. II. Control of melanin synthesis in cell cultures of the Harding-Passey melanoma].
Topics: Animals; Carbon Isotopes; Culture Techniques; Depression, Chemical; Dihydroxyphenylalanine; Leucine; | 1970 |
[Effects of proflavine on DNA metabolism in hamster melanoma].
Topics: Acridines; Animals; Antimetabolites; Cell Nucleus; Cricetinae; DNA, Neoplasm; Female; Liver; Melanom | 1970 |
[Utilization of pyrimidine precursors in the tumor and liver of mice with Ehrlich ascites carcinoma].
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine; DNA; DNA, Neoplasm; Liver; Male; Melan | 1970 |
Cell cycle characteristics of human solid tumors in vivo.
Topics: Biopsy; Breast Neoplasms; Cell Count; Cell Differentiation; DNA; DNA, Neoplasm; Humans; Kinetics; Me | 1970 |
Kinetic parameters and growth curves for experimental tumor systems.
Topics: Adenocarcinoma; Animals; Autoradiography; Benz(a)Anthracenes; Carcinoma, Ehrlich Tumor; Female; Kine | 1970 |
[Radioautographic study of the cell cycle of a Harding-Passey melanoma in culture].
Topics: Autoradiography; Culture Techniques; Melanoma; Mitosis; Neoplasm Transplantation; Neoplasms, Experim | 1971 |
[3H-Thymidine incorporation into mouse and rat tissues under in vivo and in vitro conditions].
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Nucleus; In Vitro Techniques; Liver; Melanoma; Mice; | 1967 |
Studies of leukocyte kinetics in chronic lymphocytic leukemia.
Topics: Aged; Autoradiography; Female; Humans; Injections, Intravenous; Kinetics; Leukemia, Lymphoid; Leukoc | 1968 |
[Radiation-sensitivity of DNA synthesis and mitosis in the Harding-Passey melanoma and small intestine of the mouse. Biochemical and autoradiographic studies with radioactive thymidine].
Topics: Animals; Autoradiography; Carbon Isotopes; DNA; DNA, Neoplasm; Intestine, Small; Male; Melanoma; Mic | 1968 |
Lymphoid cellular responses in the blood after immunization in man.
Topics: Antibody Formation; Antigen-Antibody Reactions; Autoradiography; Carcinoma; DNA; Endoplasmic Reticul | 1969 |
Amino acids as stimulating agents of DNA replication in melanomas. II. Stimulation in in-situ melanomas.
Topics: Amino Acids; Animals; Chromatography, Ion Exchange; DNA Replication; Fishes; Melanoma; Methods; Seaw | 1969 |