thymidine and Melanoma studies

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

Excerpt	Relevance	Reference
"Here, we examined the potential of blocking the thymidine de novo synthesis pathways for sensitizing melanoma cells to the nucleoside salvage pathway targeting endogenous DNA irradiation."	7.85	Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma. ( Drude, N; El Moussaoui, L; Kaiser, HJ; Miran, T; Morgenroth, A; Mottaghy, FM; Vogg, ATJ; von Felbert, V, 2017)
" Although the two agents may interact in the biosynthetic pathway for thymidine, we investigated, as an alternative mechanism, the regulation of susceptibility of the A375 human melanoma to natural killers activated by interferon."	7.68	Abrogation of interferon-induced resistance to interferon-activated major histocompatibility complex-unrestricted killers by treatment of a melanoma cell line with 5-fluorouracil. ( Glass, J; Neefe, JR, 1991)
"A sulfur-containing amino acid compound, S-allyl cysteine (SAC), derived from garlic extract inhibited proliferation of nine human and murine melanoma cell line in a dose-dependent manner (1."	7.68	Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine. ( Hoon, DS; Irie, RF; Morton, DL; Saxton, RE; Takeyama, H, 1993)
"The effect of tamoxifen on the growth of malignant melanoma was investigated using human cell lines and single-cell suspensions prepared from patients' tumours cultured in soft agar."	7.67	The effect of tamoxifen on the growth of human malignant melanoma in vitro. ( De Young, NJ; Gill, PG; Horsfall, DJ; Keightley, DD; Thompson, A, 1984)
"The cytotoxic effect of cis-diamminedichloroplatinum(II) (cis-DDP), as measured by a dye exclusion assay was much more pronounced in bone marrow cells and phytohemagglutinin (PHA)-stimulated lymphocytes than in a human melanoma cell line."	7.67	Cis-diamminedichloroplatinum(II) toxicity in human melanoma cells and lymphocytes as related to cellular platinum accumulation, DNA cross-linking and inhibition of DNA synthesis. ( Hansson, J; Lewensohn, R; Ringborg, U, 1988)
"Sodium cyanate injected IP at a dose level of 200 or 250 mg/kg caused a 90% or greater inhibition of the incorporation of [3H]thymidine into DNA of B16 melanoma transplanted SC in mice."	7.67	Effects of sodium cyanate in mice bearing B16 melanoma. ( Carpenter, L; Hill, GJ; Hill, HZ; Lea, MA; Luke, A; Martinson, CF; Velazquez, O, 1986)
"In the human melanoma cell line MM127 , the melphalan survival curve was linear and exhibited reciprocity with respect to concentration and treatment time."	7.67	Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. ( Parsons, PG, 1984)
"0 microCi/ml (methyl-3H)thymidine (3H-TdR) the growth rate of 6 human melanoma lines and 1 subline progressively slowed then stopped, a change that was accompanied by loss of reproductive viability as assessed by colony formation in agar, but unaccompanied by a comparable inhibition of thymidine incorporation."	7.66	Tritiated-thymidine-induced increased DNA content and irreversible differentiation in a human melanoma cell line. ( Sheridan, JW; Simmons, RJ, 1981)
"3,4-Dihydroxybenzylamine (DHBA), a dopamine analog, was much less toxic than dopamine when tested against the B16 melanoma in vivo and in vitro."	7.66	3,4-Dihydroxybenzylamine: a dopamine analog with enhanced antitumor activity against B16 melanoma. ( Wick, MM, 1979)
"The effect of thymidine (TdR) on the growth of a human melanoma transplanted in nude mice has been studied."	7.65	Effect of excess thymidine on the growth of human melanoma cells transplanted in thymus deficient nude mice. ( Giovanella, BC; Lee, SS; Stehlin, JS, 1977)
"Cultured human malignant melanoma cells, when added to normal human lymphocytes stimulated to proliferate by mitogen or antigen, were found to inhibit the uptake of 3H-thymidine (3H-T) by the lymphocytes."	7.65	Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes. ( Dent, PB; Liao, SK; Lui, VK, 1977)
"Fusarochromanone has been shown to have both stimulatory and inhibitory effects on various mammalian cells, depending on the concentration used."	5.34	Inhibitory effects of fusarochromanone on melanoma growth. ( Culberson, C; Dréau, D; Foster, M; Hogg, M; Nunes, P; Wuthier, RE, 2007)
" Dose-response curves were determined using a 5-day incubation period and 6-h terminal [3H]thymidine-labelling period."	5.29	Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays. ( Baguley, BC; Finlay, GJ; Holdaway, KM; Marshall, ES; Matthews, JH; Nixon, J; Shaw, JH; Tumewu, P, 1994)
"[3H]Thymidine uptake was inhibited by 12%, but no inhibition was detected in [3H]thymidine incorporation."	5.27	High-dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line. ( DiSorbo, DM; Nathanson, L, 1983)
"Kinetics of immunological parameters such as natural killer (NK) cell activity and tritium-thymidine uptake rate of T lymphocytes by phytohemagglutinin stimulation were investigated using peripheral leukocyte fractions of melanoma patients treated with hyperthermic isolated limb perfusion (HILP)."	5.08	Kinetics of immunological parameters in patients with malignant melanoma treated with hyperthermic isolated limb perfusion. ( Hori, Y; Mashino, T; Matsuda, K; Mayumi, H; Nagae, S; Nakao, T; Nakayama, J; Takahashi, S; Tominaga, R; Yasui, H, 1997)
"Here, we examined the potential of blocking the thymidine de novo synthesis pathways for sensitizing melanoma cells to the nucleoside salvage pathway targeting endogenous DNA irradiation."	3.85	Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma. ( Drude, N; El Moussaoui, L; Kaiser, HJ; Miran, T; Morgenroth, A; Mottaghy, FM; Vogg, ATJ; von Felbert, V, 2017)
"The effect of congeners of nitrogen monoxide (NO) on iron (Fe) uptake from 59Fe-125I-transferrin (Tf) and release of 59Fe from prelabelled cells have been investigated in SK-MEL-28 human melanoma cells, human K562 cells and mouse MDW-4 cells."	3.69	Nitrogen monoxide decreases iron uptake from transferrin but does not mobilise iron from prelabelled neoplastic cells. ( Neumannova, V; Ponka, P; Richardson, DR, 1995)
"We used computerized image analysis, immunohistochemistry, and the incorporation of tritiated thymidine to study the relationship between nuclear size and shape and the proliferation of malignant melanoma cells."	3.69	Karyometry of primary and metastatic malignant melanoma. A correlation with cell proliferation. ( Piérard, GE; Piérard-Franchimont, C, 1994)
"Uptake of tritiated thymidine, L-leucine, L-methionine and FDG into two human tumor cell lines (HTB 63 melanoma and HTB 77 IP3 ovarian carcinoma) was determined after a 4-hr exposure to each of three different oxygen atmospheres (0, 1."	3.69	Effects of hypoxia on the uptake of tritiated thymidine, L-leucine, L-methionine and FDG in cultured cancer cells. ( Clavo, AC; Wahl, RL, 1996)
" Although the two agents may interact in the biosynthetic pathway for thymidine, we investigated, as an alternative mechanism, the regulation of susceptibility of the A375 human melanoma to natural killers activated by interferon."	3.68	Abrogation of interferon-induced resistance to interferon-activated major histocompatibility complex-unrestricted killers by treatment of a melanoma cell line with 5-fluorouracil. ( Glass, J; Neefe, JR, 1991)
" Some boron compounds have recently been proposed for BNCT of malignant melanomas; the synthesized L- and D- forms of carboranylalanine and the previously tested compound L-p-boronophenylalanine are candidates."	3.68	Penetration and binding of L- and D-carboranylalanine in human melanoma spheroids. ( Carlsson, J; Lindström, P; Olsson, P; Pettersson, OA; Sjöberg, S, 1993)
"A sulfur-containing amino acid compound, S-allyl cysteine (SAC), derived from garlic extract inhibited proliferation of nine human and murine melanoma cell line in a dose-dependent manner (1."	3.68	Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine. ( Hoon, DS; Irie, RF; Morton, DL; Saxton, RE; Takeyama, H, 1993)
"The prognostic role of cell kinetics (expressed as 3H-thymidine labelling index, 3H-TdR LI) was assessed on 145 patients with pathologic stage II melanoma subjected only to therapeutic lymph node dissection."	3.68	Cell kinetics: an independent prognostic variable in stage II melanoma of the skin. ( Cascinelli, N; Clemente, C; Costa, A; Grignolio, E; Mezzanotte, G; Silvestrini, R; Vaglini, M, 1990)
"Intracellular deoxyribonucleotide pools were examined before and after thymidine treatment in highly sensitive T-lymphoid cells, relatively resistant B-lymphoid cells and moderately sensitive melanoma cells."	3.67	Diverse deoxyribonucleotide profiles in cultured human cells with differential sensitivity to thymidine. ( Appel, H; Leyva, A; Pinedo, HM, 1984)
"The rates of incorporation of 2-14C-thymidine into DNA of melanoma B16, bone marrow, gastrointestinal mucosa, spleen and liver at various time after administration of dianhydrogalactitol (DAG), 3,4-diacetyldianhydrogalactitol (DiacDAG) and 3,4-disuccinyldianhydrogalactitol (DisuDAG) at maxima nonlethal single doses to tumor-bearing mice were studied."	3.67	Damages of DNA synthesis in normal and tumor cells with sugar alcohol derivatives. ( Elekes, I; Gorbacheva, LB; Otvös, L; Sokolova, IS, 1984)
"Two drugs known to inhibit the action of calmodulin, prochlorperazine offP) and N-(6-aminohexyl)-5-chloro-1-napthalene sulfonamide (W7), were investigated for their ability to control cell proliferation in murine B16 melanoma cells in culture."	3.67	Effects of extracellular calmodulin and calmodulin antagonists on B16 melanoma cell growth. ( Bleehen, SS; Mac Neil, S; Senior, HJ; Tomlinson, S; Walker, SW, 1984)
"In the human melanoma cell line MM127 , the melphalan survival curve was linear and exhibited reciprocity with respect to concentration and treatment time."	3.67	Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. ( Parsons, PG, 1984)
"The effect of tamoxifen on the growth of malignant melanoma was investigated using human cell lines and single-cell suspensions prepared from patients' tumours cultured in soft agar."	3.67	The effect of tamoxifen on the growth of human malignant melanoma in vitro. ( De Young, NJ; Gill, PG; Horsfall, DJ; Keightley, DD; Thompson, A, 1984)
" Explants of X56, an adenocarcinoma of colon, and HXG2, an amelanotic melanoma, both maintained by serial transplantation in athymic mice, were sequentially incubated in vitro with 14C-thymidine, one of several concentrations of adriamycin, and then 3H-thymidine."	3.67	Adriamycin response of two human tumor xenografts using a double-radiolabel organ culture method. ( Sullivan, JL; Sullivan, LG, 1989)
"The cytotoxic effect of cis-diamminedichloroplatinum(II) (cis-DDP), as measured by a dye exclusion assay was much more pronounced in bone marrow cells and phytohemagglutinin (PHA)-stimulated lymphocytes than in a human melanoma cell line."	3.67	Cis-diamminedichloroplatinum(II) toxicity in human melanoma cells and lymphocytes as related to cellular platinum accumulation, DNA cross-linking and inhibition of DNA synthesis. ( Hansson, J; Lewensohn, R; Ringborg, U, 1988)
"The anti-tumour methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide (MTIC) increased the thymidine and deoxycytidine pools but not the deoxyguanosine pool in human melanoma cells."	3.67	Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells. ( Hayward, IP; Parsons, PG, 1984)
"Chloroquinoxaline sulfonamide (CQS), a chlorinated derivative of sulfaquinoxaline (SQ), inhibited proliferation of murine B16 melanoma cells, but only when relatively high drug concentrations (1 mM) were used."	3.67	Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells. ( Branda, RF; McCormack, JJ; Perlmutter, CA, 1988)
"The 3H-thymidine labeling index (LI) was determined on 178 lesions, four of which were primary, from 129 patients with malignant melanoma."	3.67	Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin. ( Attili, A; Clemente, C; Costa, A; Grignolio, E; Silvestrini, R; Testori, A, 1987)
"Sodium cyanate injected IP at a dose level of 200 or 250 mg/kg caused a 90% or greater inhibition of the incorporation of [3H]thymidine into DNA of B16 melanoma transplanted SC in mice."	3.67	Effects of sodium cyanate in mice bearing B16 melanoma. ( Carpenter, L; Hill, GJ; Hill, HZ; Lea, MA; Luke, A; Martinson, CF; Velazquez, O, 1986)
"The growth inhibitory effects, the reduction of [3H]-TdR incorporation and the perturbation of the cell cycle induced by the new agent mitozolomide on the M14 human melanoma cell line and on the SW626 human ovarian cancer cell line were compared to those produced by BCNU."	3.67	Mitozolomide activity on human cancer cells in vitro. ( D'Incalci, M; Erba, E; Landoni, F; Lorico, A; Mangioni, C; Morasca, L; Pepe, S; Ubezio, P, 1986)
"0 microCi/ml (methyl-3H)thymidine (3H-TdR) the growth rate of 6 human melanoma lines and 1 subline progressively slowed then stopped, a change that was accompanied by loss of reproductive viability as assessed by colony formation in agar, but unaccompanied by a comparable inhibition of thymidine incorporation."	3.66	Tritiated-thymidine-induced increased DNA content and irreversible differentiation in a human melanoma cell line. ( Sheridan, JW; Simmons, RJ, 1981)
"The chemotherapeutic activity of thymidine (dThd) was tested against four human tumor xenografts growing in nude mice, including a melanoma, an oat cell carcinoma of the lung, a colon carcinoma, and a breast carcinoma."	3.66	Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice. ( Howell, SB; Jenkins, RS; Streifel, J, 1979)
" implanted B-16 melanomas as well as of human melanomas have been incubated for 5 h with (H3) Uridine and (H3) Thymidine in the presence of different chemotherapeutical agents, whose concentration was equivalent to the tenfold therapeutical daily dose in men."	3.66	[In vitro and in vivo sensitivity of animal and human melanomas to various chemotherapeutical agents]. ( Rothmann, D; Schneider, O; Schussmann, M; Wiskemann, A, 1978)
"3,4-Dihydroxybenzylamine (DHBA), a dopamine analog, was much less toxic than dopamine when tested against the B16 melanoma in vivo and in vitro."	3.66	3,4-Dihydroxybenzylamine: a dopamine analog with enhanced antitumor activity against B16 melanoma. ( Wick, MM, 1979)
"Cultured human malignant melanoma cells, when added to normal human lymphocytes stimulated to proliferate by mitogen or antigen, were found to inhibit the uptake of 3H-thymidine (3H-T) by the lymphocytes."	3.65	Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes. ( Dent, PB; Liao, SK; Lui, VK, 1977)
"Single doses of 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea caused transient suppression of [3H]thymidine incorporation into DNA in bone marrow and gastrointestinal mucosa and more prolonged inhibition of such incorporation in B16 melanoma."	3.65	Inhibition and recovery of DNA synthesis in host tissues and sensitive and resistant B16 melanoma after 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, a predictor of therapeutic efficacy. ( Brereton, HD; Bryant, TL; Young, RC, 1975)
"The effect of thymidine (TdR) on the growth of a human melanoma transplanted in nude mice has been studied."	3.65	Effect of excess thymidine on the growth of human melanoma cells transplanted in thymus deficient nude mice. ( Giovanella, BC; Lee, SS; Stehlin, JS, 1977)
"When cells of a Syrian hamster melanoma were grown in increasing concentrations of bromodeoxyuridine (BrdU), lines of mutant cells able to grow well at high concentrations of BrdU were isolated."	3.65	Bromodeoxyuridine dependence--a new mutation in mammalian cells. ( Bick, MD; Davidson, RL, 1973)
"Tumorigenicity of mouse melanoma cells is reduced or lost upon growth in vitro in 1 to 3 mug/ml of 5-bromodeoxyuridine (BUdR)."	3.65	Suppression of malignancy and differentiation in melanotic melanoma cells. ( Bruce, SA; Silagi, S, 1970)
"Fusarochromanone has been shown to have both stimulatory and inhibitory effects on various mammalian cells, depending on the concentration used."	1.34	Inhibitory effects of fusarochromanone on melanoma growth. ( Culberson, C; Dréau, D; Foster, M; Hogg, M; Nunes, P; Wuthier, RE, 2007)
"Malignant melanoma is a cancer whose incidence is rising rapidly, but the mechanism by which normal melanocytes become malignant in vivo is still little understood."	1.31	Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling. ( Geissinger, E; Schartl, M; Troppmair, J; Weisser, C; Wellbrock, C, 2002)
" Dose-response curves were determined using a 5-day incubation period and 6-h terminal [3H]thymidine-labelling period."	1.29	Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays. ( Baguley, BC; Finlay, GJ; Holdaway, KM; Marshall, ES; Matthews, JH; Nixon, J; Shaw, JH; Tumewu, P, 1994)
"In the search for cytokines whose antiproliferative action could be enhanced by combination with dipyridamole, 2,6-bis(diethanolamino)-4,8-dipiperidinopyrimido[5,4-d]pyrim idine, the combination of tumor necrosis factor-alpha (TNF-alpha) with this agent was evaluated in various human tumor cell lines."	1.29	Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines. ( Kojima, T; Sekiya, S; Sugano, I; Suzuki, N; Takakubo, Y; Yamamori, H, 1995)
"Fotemustine (S 10036) is a new anti-tumor nitrosourea characterized by a phosphonoalanine carrier group coupled to the nitrosourea moiety, which potentially increases the cellular penetration of the drug."	1.28	In vitro chemosensitivity testing of Fotemustine (S 10036), a new antitumor nitrosourea. ( Bizzari, JP; Deloffre, P; Etienne, MC; Fischel, JL; Formento, P; Frenay, M; Gioanni, J; Milano, G, 1990)
"[3H]Thymidine uptake was inhibited by 12%, but no inhibition was detected in [3H]thymidine incorporation."	1.27	High-dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line. ( DiSorbo, DM; Nathanson, L, 1983)
"Treatment with indomethacin blocks prostaglandin synthesis and induces thermosensitivity."	1.27	Natural thermal resistance of human tumor cells and the role of prostaglandin. ( Hildebrand-Zanki, S; Kern, DH; Morton, DL; Roe, DJ; Storm, FK; Worth, GD, 1983)
" The method allows large numbers of replicate samples so that quantitation of dose-response relationships is simple and statistically robust, and simultaneous monitoring of cell attachment and growth within the same sample is routine."	1.27	Use of growth-attachment correlation plots to analyse human melanoma cell dependency on 2-oxocarboxylates and serum. ( Ellem, KA; Kay, GF, 1985)
"Thymidine incorporation was measured at frequent intervals after heat shock to determine the time of onset of the next DNA synthetic period."	1.27	Delay in entry into S phase after heat shock. ( Dewey, DL; Holden, JL, 1984)
"Fourteen of 20 lung cancer patients responded to lung cancer antigen, whereas only 11 of 41 patients with other tumors and 3 of 19 normal subjects reacted."	1.26	A rapid assay for stimulation of human lymphocytes by tumor-associated antigens. ( Grimm, EA; Morton, DL; Roth, JA, 1976)
"The cytotoxic action of lymphocytes on cancer cells in vitro indicates sensitization of the patient against his own tumor."	1.25	[The lymphocyte cytotoxicity test in tumor immunology (author's transl)]. ( Pees, HW, 1975)
"More precise definition of the cytokinetic parameters of human tumor growth will clearly help both in predicting the outcome of disease in individual patients and in planning the dosage schedules of single chemotherapeutic agents and combinations of agents to achieve optimal results."	1.25	Growth kinetics of solid tumors. Implications for chemotherapy. ( Curby, WA; Rosenoer, VM, 1975)
"Cycloheximide treatment (1-5 microg/ml) of heterokaryons during the preceding lag period inhibits the initiation of macrophage DNA synthesis, in a reversible fashion."	1.25	Macrophage-melanoma cell heterokaryons. 3. The activation of macrophage DNA synthesis. Studies with inhibitors of protein synthesis and with synchronized melanoma cells. ( Cohn, Z; Gordon, S, 1971)
"Serum from cancer patients impaired the response of normal lymphocytes."	1.25	The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients. ( Kumar, S; Taylor, G, 1973)
"The cytokinetics of subcutaneous metastases in five patients with melanoma was studied."	1.25	Cell proliferation in human melanoma. ( Frei, E; Luce, JK; Shirakawa, S; Tannock, I, 1970)

Timeframe	Studies, this research(%)	All Research%
pre-1990	148 (75.90)	18.7374
1990's	31 (15.90)	18.2507
2000's	13 (6.67)	29.6817
2010's	3 (1.54)	24.3611
2020's	0 (0.00)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
Mature Dendritic Cell Vaccination Against gp100 in Patients With Advanced Melanoma[NCT00683670]			Phase 1	17 participants (Actual)	Interventional	2008-08-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Bromodeoxyuridine mutagenesis and deoxyribonucleotide pool imbalance in mammalian cells. Basic life sciences, 1985, Volume: 31 Topics: Animals; Base Composition; Bromodeoxyuridine; Cell Line; Cricetinae; Cytarabine; Deoxyadenosines; De	1985
Evidence for immune reactivity against neoplasms. Transplantation reviews, 1971, Volume: 7 Topics: Animals; Antibodies; Antibody Formation; Antigens; Antigens, Neoplasm; Antigens, Viral; Binding Site	1971

Article	Year
Randomized, placebo-controlled pilot trial of the effects of alpha-tocopherol supplementation on levels of autoantibodies against 5-hydroxymethyl-2-deoxyuridine in melanoma patients. Melanoma research, 2004, Volume: 14, Issue:1 Topics: alpha-Tocopherol; Antineoplastic Agents; Antioxidants; Autoantibodies; Dietary Supplements; DNA Dama	2004
Kinetics of immunological parameters in patients with malignant melanoma treated with hyperthermic isolated limb perfusion. Journal of dermatological science, 1997, Volume: 15, Issue:1 Topics: Adult; Aged; Extremities; Female; Humans; Hyperthermia, Induced; Intercellular Adhesion Molecule-1;	1997
Clinical and biochemical studies of high-dose intermittent therapy of solid tumors with hydroxyurea (NSC-32065). Cancer chemotherapy reports, 1970, Volume: 54, Issue:3 Topics: Adult; Aged; Blood Urea Nitrogen; Chondrosarcoma; Clinical Trials as Topic; Depression, Chemical; DN	1970

Article	Year
Dual addressing of thymidine synthesis pathways for effective targeting of proliferating melanoma. Cancer medicine, 2017, Volume: 6, Issue:7 Topics: Animals; Antineoplastic Agents; Biomarkers; Biosynthetic Pathways; Cell Cycle Checkpoints; Cell Line	2017
Germline analysis of thymidine/guanidine polymorphism at position 309 of the Mdm2 promoter in malignant melanoma patients. Melanoma research, 2009, Volume: 19, Issue:4 Topics: Adult; Aged; Aging; DNA; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germ C	2009
Use of DNA microarray and small animal positron emission tomography in preclinical drug evaluation of RAF265, a novel B-Raf/VEGFR-2 inhibitor. Neoplasia (New York, N.Y.), 2011, Volume: 13, Issue:3 Topics: Animals; Biomarkers, Tumor; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Fluorodeoxygluc	2011
Topical application of thymidine dinucleotide to newborn mice reduces and delays development of UV-induced melanomas. The Journal of investigative dermatology, 2012, Volume: 132, Issue:11 Topics: Administration, Topical; Animals; Animals, Newborn; Melanoma; Mice; Mice, Knockout; Neoplasms, Radia	2012
Effects of native and cleaved forms of alpha1-antitrypsin on ME 1477 tumor cell functional activity. Cancer detection and prevention, 2002, Volume: 26, Issue:4 Topics: alpha 1-Antitrypsin; Enzyme Activation; Humans; Male; Melanoma; Metalloendopeptidases; Middle Aged;	2002
[RADIOAUTOGRAPHICAL STUDY OF THE PROLIFERATIVE ACTIVITY OF THE VARIOUS TYPES OF CELLULAR ELEMENTS IN A MELANOTIC SARCOMA OF THE IRIS AND CILIARY BODY]. Bollettino d'oculistica, 1963, Volume: 42 Topics: Autoradiography; Ciliary Body; DNA; DNA, Neoplasm; Eye Neoplasms; Humans; Iris; Melanoma; Metabolism	1963
INCORPORATION OF TRITIATED THYMIDINE BY OCULAR TUMORS IN VITRO. American journal of ophthalmology, 1965, Volume: 60 Topics: Cell Division; Eye Neoplasms; In Vitro Techniques; Melanoma; Metabolism; Research Design; Retinoblas	1965
Depletion of endogenous nitric oxide enhances cisplatin-induced apoptosis in a p53-dependent manner in melanoma cell lines. The Journal of biological chemistry, 2004, Jan-02, Volume: 279, Issue:1 Topics: Apoptosis; Cell Cycle; Cell Division; Cisplatin; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; DNA	2004
Bisindenoisoquinoline bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA intercalator and topoisomerase inhibitor with antitumor activity. Molecular pharmacology, 2006, Volume: 70, Issue:3 Topics: Animals; Antineoplastic Agents; Catalysis; Cell Death; DNA; DNA Damage; DNA Topoisomerases, Type II;	2006
Cytotoxic activity of Apomine is due to a novel membrane-mediated cytolytic mechanism independent of apoptosis in the A375 human melanoma cell line. Investigational new drugs, 2007, Volume: 25, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Cell Membrane; Cell Survival; Cytosol;	2007
Inhibitory effects of fusarochromanone on melanoma growth. Anti-cancer drugs, 2007, Volume: 18, Issue:8 Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Chromones; Humans; Immunohis	2007
Serial analysis of melanoma growth kinetics in a patient receiving bleomycin and procarbazine therapy: comparison of tumor volume, flow cytometry, and thymidine labeling techniques. Cancer treatment reports, 1982, Volume: 66, Issue:3 Topics: Autoradiography; Bleomycin; Cell Division; DNA, Neoplasm; Female; Flow Cytometry; Humans; Melanoma;	1982
Effects of calcium depletion on human cells in vitro and the anomalous behavior of the human melanoma cell line MM170. Cancer research, 1983, Volume: 43, Issue:5 Topics: Calcium; Cell Division; Cell Line; Cell Membrane; DNA; Egtazic Acid; Ethylene Glycols; Humans; Inter	1983
Correlation between immunosuppressive agents from media of human malignant melanoma cell cultures and from human serum. Clinical immunology and immunopathology, 1981, Volume: 20, Issue:2 Topics: Animals; Blood; Cell Line; Cells, Cultured; Chemical Fractionation; Chromatography, Gel; Culture Med	1981
Diverse deoxyribonucleotide profiles in cultured human cells with differential sensitivity to thymidine. Cancer biochemistry biophysics, 1984, Volume: 7, Issue:3 Topics: B-Lymphocytes; Cell Line; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; Deoxyribonucleotides;	1984
In vitro activation of cyclophosphamide for an in vitro chemosensitivity assay. Journal of surgical oncology, 1984, Volume: 26, Issue:4 Topics: Aminopyrine N-Demethylase; Animals; Biotransformation; Cell Survival; Cyclophosphamide; Dose-Respons	1984
Damages of DNA synthesis in normal and tumor cells with sugar alcohol derivatives. Neoplasma, 1984, Volume: 31, Issue:6 Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Line; Dianhydrogalactitol; DNA; Injections, Intrap	1984
Epigenetic effects of the methylating agent 5-(3-methyl-1-triazeno) imidazole-4-carboxamide in human melanoma cells. The Australian journal of experimental biology and medical science, 1984, Volume: 62 ( Pt 5) Topics: Alkylating Agents; Antineoplastic Agents; Cell Line; Dacarbazine; Deoxycytidine; Deoxyguanosine; Gen	1984
The effect of tamoxifen on the growth of human malignant melanoma in vitro. European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:6 Topics: Cell Count; Cell Division; Cell Line; Humans; Melanoma; Receptors, Estrogen; Receptors, Progesterone	1984
Production of the effector molecule thymidine by human lung alveolar macrophages. European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:12 Topics: Animals; Ascitic Fluid; Biological Assay; Cells, Cultured; Chromatography, Thin Layer; Humans; Macro	1984
Natural thermal resistance of human tumor cells and the role of prostaglandin. Surgery, 1983, Volume: 94, Issue:2 Topics: Cell Line; Cell Membrane; Dinoprostone; Drug Evaluation; Hot Temperature; Humans; Indomethacin; Mela	1983
Thymidine sensitivity and deoxynucleotide pools of human lymphoid and melanoma cells in vitro. Advances in experimental medicine and biology, 1984, Volume: 165 Pt B Topics: Cell Line; Chromatography, High Pressure Liquid; Deoxyribonucleotides; Humans; Kinetics; Leukemia, L	1984
High-dose pyridoxal supplemented culture medium inhibits the growth of a human malignant melanoma cell line. Nutrition and cancer, 1983, Volume: 5, Issue:1 Topics: Cell Division; Cells, Cultured; Glucose; Humans; In Vitro Techniques; Leucine; Male; Melanoma; Pyrid	1983
Cytotoxic and biochemical effects of thymidine and 3-deazauridine on human tumor cells. Cancer research, 1984, Volume: 44, Issue:6 Topics: 3-Deazauridine; Adrenal Gland Neoplasms; Cell Division; Cell Line; Cell Survival; Deoxyribonucleotid	1984
Dependence on treatment time of melphalan resistance and DNA cross-linking in human melanoma cell lines. Cancer research, 1984, Volume: 44, Issue:7 Topics: Caffeine; Cell Line; Cell Survival; Chlorambucil; DNA, Neoplasm; Drug Resistance; Drug Synergism; Ho	1984
Delay in entry into S phase after heat shock. Cell and tissue kinetics, 1984, Volume: 17, Issue:4 Topics: Animals; Cell Line; DNA; Hot Temperature; Interphase; Melanoma; Mice; Thymidine; Time Factors	1984
Effects of extracellular calmodulin and calmodulin antagonists on B16 melanoma cell growth. The Journal of investigative dermatology, 1984, Volume: 83, Issue:1 Topics: Animals; Calmodulin; Cell Line; Cells, Cultured; Culture Media; DNA, Neoplasm; Dose-Response Relatio	1984
In vitro growth inhibition of human malignant melanoma cells by glucocorticoids. Cancer research, 1983, Volume: 43, Issue:6 Topics: Cell Division; Cell Line; Glucocorticoids; Humans; Melanoma; Progesterone; Receptors, Glucocorticoid	1983
Difference in 3H-thymidine incorporation after irradiation between murine B16 melanoma and squamous cell carcinoma in vivo. Gan, 1983, Volume: 74, Issue:2 Topics: Animals; Carcinoma, Squamous Cell; Cell Cycle; Cell Division; Dose-Response Relationship, Radiation;	1983
Effect of estradiol and degree of cell differentiation on human melanoma susceptibility to killing by monoclonal antibodies. Immunology letters, 1982, Volume: 4, Issue:1 Topics: Animals; Antibodies, Monoclonal; Cell Line; Cell Transformation, Neoplastic; Cells, Cultured; Comple	1982
Detection of a 10 kb DNA replication intermediate in human melanoma cells. Chromosoma, 1982, Volume: 84, Issue:5 Topics: Cells, Cultured; Centrifugation, Density Gradient; DNA; DNA Replication; DNA, Single-Stranded; Elect	1982
Formation of a new population of DNA replication intermediates in X-irradiated human melanoma cells. Carcinogenesis, 1982, Volume: 3, Issue:7 Topics: Cells, Cultured; DNA Replication; Humans; Melanoma; Neoplasms, Experimental; Thymidine	1982
The reversibility of cancer: evidence that malignancy in melanoma cells is gamma-linolenic acid deficiency-dependent. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1982, Oct-02, Volume: 62, Issue:15 Topics: Animals; Cattle; Cell Count; Cell Transformation, Neoplastic; Cells, Cultured; Dose-Response Relatio	1982
Tritiated-thymidine-induced increased DNA content and irreversible differentiation in a human melanoma cell line. British journal of experimental pathology, 1981, Volume: 62, Issue:3 Topics: Cell Count; Cell Differentiation; Cell Line; DNA, Neoplasm; Humans; Melanoma; Mitotic Index; Thymidi	1981
Biophysical and morphological correlates of kinetic change and death in a starved human melanoma cell line. Journal of cell science, 1981, Volume: 49 Topics: Biophysical Phenomena; Biophysics; Cell Line; Cell Separation; Cell Survival; Humans; Kinetics; Mela	1981
Melphalan prevents the formation of double-stranded DNA replication intermediates in human malignant melanoma cells. Carcinogenesis, 1981, Volume: 2, Issue:12 Topics: Cell Division; Cells, Cultured; DNA Replication; Humans; Kinetics; Melanoma; Melphalan; Thymidine; T	1981
Dipyridamole combined with tumor necrosis factor-alpha enhances inhibition of proliferation in human tumor cell lines. Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:8 Topics: Amino Acids; Animals; Antigens, Neoplasm; Antineoplastic Combined Chemotherapy Protocols; Carbon Rad	1995
Nitrogen monoxide decreases iron uptake from transferrin but does not mobilise iron from prelabelled neoplastic cells. Biochimica et biophysica acta, 1995, May-12, Volume: 1266, Issue:3 Topics: Animals; Cell Line; Cyclic GMP; Humans; Iodine Radioisotopes; Iron; Iron Radioisotopes; Melanoma; Mi	1995
Cell-binding and growth-stimulating activities of the C-terminal part of human MGSA/Gro alpha. Biochemical and biophysical research communications, 1995, Jan-17, Volume: 206, Issue:2 Topics: Amino Acid Sequence; Binding Sites; Cell Division; Cell Line; Chemokine CXCL1; Chemokines, CXC; Chem	1995
Karyometry of primary and metastatic malignant melanoma. A correlation with cell proliferation. The American Journal of dermatopathology, 1994, Volume: 16, Issue:3 Topics: Cell Division; Cell Nucleus; Humans; Karyometry; Melanoma; Prognosis; Skin Neoplasms; Thymidine	1994
Radiosensitivity of new and established human melanoma cell lines: comparison of [3H]thymidine incorporation and soft agar clonogenic assays. European journal of cancer (Oxford, England : 1990), 1994, Volume: 30A, Issue:9 Topics: Adult; Aged; Cell Survival; Dose-Response Relationship, Radiation; Female; Humans; Male; Melanoma; M	1994
Catechol-O-methyltransferase as a target for melanoma destruction? Biochemical pharmacology, 1994, Aug-17, Volume: 48, Issue:4 Topics: Anisoles; Antineoplastic Agents; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibito	1994
(R,R)-2,2'-[1,2-ethanediylbis[imino(1-methyl-2,1-ethanediyl)]]- bis[5-nitro-1H-benz[de]isoquinoline-1,3-(2H)-dione] dimethanesulfonate (DMP 840), a novel bis-naphthalimide with potent nonselective tumoricidal activity in vitro. Cancer research, 1994, Apr-15, Volume: 54, Issue:8 Topics: Amsacrine; Animals; Antineoplastic Agents; Cell Division; Clinical Trials, Phase I as Topic; Colonic	1994
In vitro antiproliferative effect of interferon alpha in solid tumors: a potential predictive test. Neoplasma, 1993, Volume: 40, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Cell Division; DNA, Neoplasm; Female; Humans; Interferon-alpha; Kidn	1993
Penetration and binding of L- and D-carboranylalanine in human melanoma spheroids. Melanoma research, 1993, Volume: 3, Issue:5 Topics: Boron Compounds; Boron Neutron Capture Therapy; Cell Aggregation; Cell Cycle; Humans; Melanoma; Phen	1993
Receptor binding and cytotoxicity studies with melanotropin fragments containing melphalan. Annals of the New York Academy of Sciences, 1993, May-31, Volume: 680 Topics: alpha-MSH; Amino Acid Sequence; Cell Division; Fibroblasts; Humans; Kinetics; Melanoma; Melphalan; M	1993
Growth inhibition and modulation of cell markers of melanoma by S-allyl cysteine. Oncology, 1993, Volume: 50, Issue:1 Topics: Animals; Cell Division; Cysteine; Dose-Response Relationship, Drug; Gangliosides; Humans; Melanins;	1993
Interleukin-1 induces growth arrest by hypophosphorylation of the retinoblastoma susceptibility gene product RB. The Journal of biological chemistry, 1996, Mar-08, Volume: 271, Issue:10 Topics: Antigens, Polyomavirus Transforming; Carrier Proteins; Cell Cycle; Cell Cycle Proteins; Cell Divisio	1996
Decreased ET(B) receptor expression in human metastatic melanoma cells. Biochemical and biophysical research communications, 1996, Feb-27, Volume: 219, Issue:3 Topics: Amino Acid Sequence; Cell Line; DNA, Neoplasm; Endothelins; Gene Expression; Humans; Kinetics; Melan	1996
Effects of hypoxia on the uptake of tritiated thymidine, L-leucine, L-methionine and FDG in cultured cancer cells. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1996, Volume: 37, Issue:3 Topics: Cell Hypoxia; Deoxyglucose; Female; Fluorodeoxyglucose F18; Humans; In Vitro Techniques; Leucine; Me	1996
A spontaneous murine melanoma lung metastasis comprised of host x tumor hybrids. Cancer research, 2000, May-01, Volume: 60, Issue:9 Topics: Aminopterin; Animals; Anti-Bacterial Agents; Antigens, CD; Antineoplastic Combined Chemotherapy Prot	2000
Radioimmunoconjugates for targeted alpha therapy of malignant melanoma. Melanoma research, 2000, Volume: 10, Issue:3 Topics: Antibodies, Monoclonal; Bismuth; Chelating Agents; DNA, Neoplasm; Humans; Immunoconjugates; Isothioc	2000
Radiation-induced cell cycle delays and p53 status of early passage melanoma cell lines. Oncology research, 2000, Volume: 12, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Cell Cycle; DNA, Neoplasm; Female; Flow Cytometry; Genes, p53; Human	2000
Intratumoral delivery of an interferon gamma retrovirus-producing cells inhibits growth of a murine melanoma by a non-immune mechanism. Cancer letters, 2001, Nov-28, Volume: 173, Issue:2 Topics: Adenoviridae; Animals; Antineoplastic Agents; Apoptosis; Cell Division; Enzyme-Linked Immunosorbent	2001
Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling. The Journal of biological chemistry, 2002, Feb-22, Volume: 277, Issue:8 Topics: Cell Cycle Proteins; Cell Differentiation; Colforsin; Cyclic AMP; DNA Primers; DNA, Neoplasm; Dual S	2002
Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues. Hybridoma and hybridomics, 2002, Volume: 21, Issue:1 Topics: Adenoma; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blotting, Western; Breast Neoplasms;	2002
[The lymphocyte cytotoxicity test in tumor immunology (author's transl)]. Klinische Wochenschrift, 1975, Volume: 53, Issue:1 Topics: Animals; Antigens, Neoplasm; B-Lymphocytes; Cells, Cultured; Chromium Radioisotopes; Culture Media;	1975
[Correlation of in vitro testing and therapeutical results in animal transplanted tumors after cytostatic treatment]. Arzneimittel-Forschung, 1975, Volume: 25, Issue:1 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Bleomycin; Carcinoma 256, Walker; Cricetinae; Dactin	1975
The use of viable frozen lymphocytes for studies in human tumor immunology. Transplantation, 1975, Volume: 19, Issue:3 Topics: Adult; Blood Preservation; Cell Separation; Cell Survival; Cells, Cultured; Concanavalin A; Cytotoxi	1975
Sensitivity tests of tumors to cytostatic agents. I. Comparative investigations on transplanted tumors in vivo and in vitro. Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1975, Volume: 83, Issue:2 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cell Division; Cricetinae; Da	1975
Maturation and differentiation of B16 melanoma cells induced by theophylline treatment. Journal of the National Cancer Institute, 1975, Volume: 54, Issue:6 Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Clone Cells; Cyclic AMP; DNA, Neoplas	1975
3,4-Dihydroxybenzylamine: a dopamine analog with enhanced antitumor activity against B16 melanoma. Journal of the National Cancer Institute, 1979, Volume: 63, Issue:6 Topics: Animals; Cells, Cultured; Dopamine; Melanoma; Mice; Mice, Inbred Strains; Neoplasms, Experimental; T	1979
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment. Seminars in oncology, 1977, Volume: 4, Issue:2 Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru	1977
Regression of human tumors established in nude mice after continuous infusion of thymidine. Cancer research, 1979, Volume: 39, Issue:8 Topics: Animals; Breast Neoplasms; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Melanoma; Mi	1979
Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice. Cancer research, 1979, Volume: 39, Issue:10 Topics: Animals; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Humans; Lung Neopl	1979
Specific protection against the cytotoxicity of a new class of nitrosoureas by pyrimidine deoxyribonucleosides. Biochemical pharmacology, 1979, Oct-01, Volume: 28, Issue:19 Topics: Animals; Cell Survival; Cells, Cultured; Deoxyribonucleosides; Leukemia L1210; Melanoma; Mice; Neopl	1979
Novel phenotypes arising from selection of hamster melanoma cells for resistance to BUdR. Experimental cell research, 1977, Volume: 107, Issue:1 Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Line; Clone Cells; Cricetinae; DNA, Neoplasm; Drug R	1977
[In vitro and in vivo sensitivity of animal and human melanomas to various chemotherapeutical agents]. Archives of dermatological research, 1978, Aug-28, Volume: 262, Issue:3 Topics: Animals; Antineoplastic Agents; Cricetinae; Drug Resistance; Humans; In Vitro Techniques; Melanoma;	1978
Inhibition of [3H]TdR and [3H]CdR incorporation in an established human lymphoma cell line by trypsin treatment. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 158, Issue:4 Topics: Animals; Cell Line; Cell Separation; Deoxycytidine; DNA, Neoplasm; HeLa Cells; Humans; Lymphoma, Non	1978
Characterisation of human malignant melanoma cell lines. VI. Inhibition of 3H-thymidine uptake by normal stimulated lymphocytes. Oncology, 1977, Volume: 34, Issue:6 Topics: Antigens, Neoplasm; Cell Line; DNA; Humans; Immunity, Cellular; In Vitro Techniques; Lectins; Lympho	1977
Dopamine: a novel antitumor agent active against B-16 melanoma in vivo. The Journal of investigative dermatology, 1978, Volume: 71, Issue:2 Topics: Animals; Antineoplastic Agents; Dopamine; Leucine; Melanoma; Mice; Neoplasms, Experimental; Thymidin	1978
Characterisation of an inhibitor of thymidine uptake produced by cultured human melanoma cells. Oncology, 1978, Volume: 35, Issue:6 Topics: Amino Acids; Cell Line; Humans; In Vitro Techniques; Kanamycin; Lymphocyte Activation; Lymphocytes;	1978
Comparative effects on growth and tumorigenicity of mouse melanoma cells by thymidine and its analogs, 5-ethyl- and 5-bromodeoxyuridine. Cancer research, 1977, Volume: 37, Issue:9 Topics: Animals; Bromodeoxyuridine; Cell Division; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Kinetics; M	1977
Effect of excess thymidine on the growth of human melanoma cells transplanted in thymus deficient nude mice. Cancer letters, 1977, Volume: 3, Issue:3-4 Topics: Animals; Cell Line; Female; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms,	1977
A rapid assay for stimulation of human lymphocytes by tumor-associated antigens. Cancer research, 1976, Volume: 36, Issue:9 pt.1 Topics: Antigens, Neoplasm; Carcinoma; Female; Hemagglutination Tests; Hemocyanins; Humans; Leucine; Lung; L	1976
A rapid in vitro labeling index method for predicting response of human solid tumors to chemotherapy. Cancer research, 1976, Volume: 36, Issue:9 pt.1 Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Drug Evaluation; Female; Humans; In Vitro	1976
[Autoradiographic study of pigmented murine melanoma]. Tsitologiia, 1976, Volume: 18, Issue:8 Topics: Animals; Autoradiography; Melanoma; Mice; Mitosis; Neoplasm Transplantation; Neoplasms, Experimental	1976
[In vitro study of peripheral blood with thymidine-3H in the diagnosis of melanoma of the skin]. Meditsinskaia radiologiia, 1976, Volume: 21, Issue:12 Topics: Blood Cells; Humans; In Vitro Techniques; Melanoma; Skin Neoplasms; Thymidine	1976
Kinetic aids to proper chemotherapeutic scheduling: labeled nucleoside incorporation studies in vivo. Cancer treatment reports, 1976, Volume: 60, Issue:12 Topics: Animals; Bone Marrow; Cell Survival; Cyclophosphamide; DNA, Neoplasm; Drug Administration Schedule;	1976
Growth kinetics of solid tumors. Implications for chemotherapy. The Medical clinics of North America, 1975, Volume: 59, Issue:2 Topics: Acute Disease; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Cul	1975
In vitro tumor cell destruction by syngeneic mouse macrophoages: methods for assaying cytotoxicity. Journal of immunological methods, 1975, Volume: 7, Issue:1 Topics: Animals; Cell Count; Cells, Cultured; Culture Techniques; Cytotoxicity Tests, Immunologic; Embryo, M	1975
Inhibition and recovery of DNA synthesis in host tissues and sensitive and resistant B16 melanoma after 1-(2-chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea, a predictor of therapeutic efficacy. Cancer research, 1975, Volume: 35, Issue:9 Topics: Animals; Bone Marrow; Cell Division; Depression, Chemical; DNA; DNA, Neoplasm; Gastric Mucosa; Intes	1975
Association of DNA with melanin granules. Journal of the National Cancer Institute, 1975, Volume: 55, Issue:3 Topics: Animals; Cytoplasmic Granules; DNA; Liver; Melanins; Melanoma; Mice; Mice, Inbred DBA; Neoplasms, Ex	1975
The production of acidic polysaccharides by 5-bromodeoxyuridine-treated B16 mouse melanoma cells. Cancer research, 1975, Volume: 35, Issue:9 Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chondroitin; Depression, Chemical; DNA; Glucosamine; Gl	1975
DNA repair and UV resistance in human melanoma. Basic life sciences, 1975, Volume: 5B Topics: Cells, Cultured; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Radiation Effects; Thymidine; Ultravio	1975
Purification and analysis of growth regulating proteins secreted by a human melanoma cell line. Melanoma research, 1992, Volume: 2, Issue:5-6 Topics: Amino Acid Sequence; Blotting, Western; Cell Division; Chromatography, Gel; Chromatography, High Pre	1992
Biological and enzymatic features of human melanoma clones with different invasive potential. Melanoma research, 1992, Volume: 2, Issue:5-6 Topics: Cell Adhesion; Cell Division; Clone Cells; Extracellular Matrix; gamma-Glutamyltransferase; Humans;	1992
Interleukin-1-inducible tumor growth arrest is characterized by activation of cell type-specific "early" gene expression programs. The Journal of biological chemistry, 1992, Mar-25, Volume: 267, Issue:9 Topics: Cell Division; Cell Line; Dactinomycin; DNA Replication; DNA, Neoplasm; Gene Expression Regulation,	1992
Interleukin-6 production by human melanoma cell lines. Lymphokine and cytokine research, 1992, Volume: 11, Issue:3 Topics: Blotting, Northern; Cell Line; DNA Replication; Enzyme-Linked Immunosorbent Assay; Humans; Interleuk	1992
Interleukin 6: a fibroblast-derived growth inhibitor of human melanoma cells from early but not advanced stages of tumor progression. Proceedings of the National Academy of Sciences of the United States of America, 1992, Oct-01, Volume: 89, Issue:19 Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Growth Inhibitors; Humans; Inter	1992
Murine monoclonal antibodies cytotoxic to human glioma cells in vitro. Histology and histopathology, 1992, Volume: 7, Issue:4 Topics: Adult; Animals; Antibodies, Monoclonal; Astrocytes; Cytotoxicity Tests, Immunologic; Glioma; Humans;	1992
Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. Cancer letters, 1992, Apr-15, Volume: 63, Issue:2 Topics: beta Carotene; Breast Neoplasms; Carotenoids; Cell Division; Cell Line; Colonic Neoplasms; DNA, Neop	1992
Evaluation of the cytotoxic mechanisms mediated by the broad-spectrum antitumor alkaloid acronycine and selected semisynthetic derivatives. Chemico-biological interactions, 1992, Volume: 81, Issue:1-2 Topics: Acronine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Cell Nucleus; Cel	1992
Purification and characterization of recombinant melanoma growth stimulating activity. Methods in enzymology, 1991, Volume: 198 Topics: Amino Acid Sequence; Animals; Biological Assay; Cell Division; Cell Line; Chemokine CXCL1; Chemokine	1991
Diffusion and binding of monoclonal antibody TNT-1 in multicellular tumor spheroids. Journal of the National Cancer Institute, 1991, Feb-06, Volume: 83, Issue:3 Topics: Adenocarcinoma; Antibodies, Monoclonal; Autoradiography; Binding Sites, Antibody; Cell Division; Col	1991
Abrogation of interferon-induced resistance to interferon-activated major histocompatibility complex-unrestricted killers by treatment of a melanoma cell line with 5-fluorouracil. Cancer research, 1991, Jun-15, Volume: 51, Issue:12 Topics: Adult; Cell Line; Cytotoxicity, Immunologic; Dose-Response Relationship, Drug; Drug Resistance; Fluo	1991
Effect of thymidine analogs on tyrosinase activity and mRNA accumulation in mouse melanoma cells. Experimental cell research, 1990, Volume: 188, Issue:1 Topics: Animals; Bromodeoxyuridine; Catechol Oxidase; Cell Line; Cell Transformation, Neoplastic; Floxuridin	1990
Nerve growth factor (NGF) induces neuronal differentiation in neuroblastoma cells transfected with the NGF receptor cDNA. Molecular and cellular biology, 1990, Volume: 10, Issue:9 Topics: Animals; Autoradiography; Cell Differentiation; Cell Line; DNA, Neoplasm; Flow Cytometry; Humans; Me	1990
Cell kinetics: an independent prognostic variable in stage II melanoma of the skin. British journal of cancer, 1990, Volume: 62, Issue:5 Topics: Adult; Aged; Cell Division; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Prognosis	1990
Antiproliferative effect of interleukin 1 (IL-1) on tumor cells: G0-G1 arrest of a human melanoma cell line by IL-1. Biochemical and biophysical research communications, 1990, Nov-30, Volume: 173, Issue:1 Topics: Cell Cycle; Cell Division; Cell Line; Clone Cells; Demecolcine; DNA Replication; Humans; Interleukin	1990
In vitro chemosensitivity testing of Fotemustine (S 10036), a new antitumor nitrosourea. Cancer chemotherapy and pharmacology, 1990, Volume: 25, Issue:5 Topics: Antineoplastic Agents; Carmustine; Cell Division; Cisplatin; Dacarbazine; Drug Screening Assays, Ant	1990
Growth inhibitory effect of sodium azide in chemosensitivity assays. International journal of cell cloning, 1987, Volume: 5, Issue:3 Topics: Azides; Biopsy; Bleomycin; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Humans;	1987
Altered formation of DNA in human cells treated with inhibitors of DNA topoisomerase II (etoposide and teniposide). Cancer research, 1989, Nov-15, Volume: 49, Issue:22 Topics: DNA Replication; DNA, Neoplasm; Etoposide; Humans; Kinetics; Melanoma; Podophyllotoxin; Teniposide;	1989
Adriamycin response of two human tumor xenografts using a double-radiolabel organ culture method. Neoplasma, 1989, Volume: 36, Issue:6 Topics: Adenocarcinoma; Animals; Carbon Radioisotopes; Colonic Neoplasms; Doxorubicin; Drug Screening Assays	1989
Autocrine tumor cell growth-inhibiting activities from human malignant melanoma. Cancer research, 1989, Oct-01, Volume: 49, Issue:19 Topics: Biological Factors; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Growth In	1989
Reduced DNA damage induced in human melanoma cells by dacarbazine in the presence of deoxyribonucleosides. Cancer research, 1989, Jun-01, Volume: 49, Issue:11 Topics: Dacarbazine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; DNA Damage; DNA, Neoplasm; Humans; Mela	1989
The effects of retinoic acid and butyric acid on in vitro migration by murine B16a cells: a quantitative scanning electron microscopic study. Scanning microscopy, 1989, Volume: 3, Issue:2 Topics: Animals; Butyrates; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Cytoskeleton; Melanom	1989
Step-wise progression of mammalian 10-kb DNA replication intermediates to mature chromatin. European journal of biochemistry, 1988, Dec-01, Volume: 178, Issue:1 Topics: Benzamides; Cell Line; Chromatin; DNA Replication; DNA, Neoplasm; Endonucleases; Humans; Melanoma; P	1988
Effect of triamcinolone acetonide on the growth of NEL-M1 human melanoma cells cultured in the presence and absence of growth stimulatory agents. Cancer research, 1986, Volume: 46, Issue:8 Topics: Cell Division; Cells, Cultured; Culture Media; ErbB Receptors; Growth Substances; Hormones; Humans;	1986
Cis-diamminedichloroplatinum(II) toxicity in human melanoma cells and lymphocytes as related to cellular platinum accumulation, DNA cross-linking and inhibition of DNA synthesis. Acta oncologica (Stockholm, Sweden), 1988, Volume: 27, Issue:4 Topics: Cell Line; Cell Survival; Cisplatin; DNA Replication; Humans; Hydrogen-Ion Concentration; Lymphocyte	1988
Cellular pharmacology of chloroquinoxaline sulfonamide and a related compound in murine B16 melanoma cells. Biochemical pharmacology, 1988, Dec-01, Volume: 37, Issue:23 Topics: Animals; Cell Division; Cell Line; Chromatography, High Pressure Liquid; Deoxyuridine; DNA; Flow Cyt	1988
Separation of melanoma growth stimulatory activity and human type-alpha transforming growth factor. Methods in enzymology, 1987, Volume: 146 Topics: Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Culture Media; DNA Replication	1987
An experimental model for studying the desmoplastic response to tumor invasion. Cancer letters, 1987, Volume: 35, Issue:3 Topics: Animals; Cell Line; Collagen; Female; Fibrosis; Hydroxyproline; Melanoma; Mice; Mice, Inbred C57BL;	1987
Preparation of a monoclonal antibody to a melanoma growth-stimulatory activity released into serum-free culture medium by Hs0294 malignant melanoma cells. Journal of cellular biochemistry, 1987, Volume: 34, Issue:3 Topics: Animals; Antibodies, Monoclonal; Cell Division; Cell Line; Culture Media; Growth Substances; Humans;	1987
Cell kinetics as a prognostic tool in patients with metastatic malignant melanoma of the skin. Cancer, 1987, Dec-01, Volume: 60, Issue:11 Topics: Adolescent; Adult; Aged; Cell Division; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metast	1987
Infection of DBA/2 or C3H/HeJ mice by intraperitoneal injection of vaccinia virus elicits activated macrophages, cytolytic and cytostatic for S91-melanoma tumor cells. Cancer immunology, immunotherapy : CII, 1986, Volume: 22, Issue:3 Topics: Animals; Cytotoxicity, Immunologic; DNA, Neoplasm; Immunotherapy; Injections, Intraperitoneal; Kille	1986
Biological characterization of an acid-sensitive growth factor from human platelets: role in the proliferation of human melanoma and bovine endothelial cells. Biochemical and biophysical research communications, 1986, Jul-31, Volume: 138, Issue:2 Topics: Animals; Aorta; Blood Platelets; Cattle; Cell Division; Cells, Cultured; Chromatography, Gel; Chroma	1986
Effects of sodium cyanate in mice bearing B16 melanoma. Cancer chemotherapy and pharmacology, 1986, Volume: 17, Issue:3 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Carmust	1986
Mitozolomide activity on human cancer cells in vitro. British journal of cancer, 1986, Volume: 54, Issue:6 Topics: Aged; Antineoplastic Agents; Carmustine; Cell Cycle; Cell Line; Dose-Response Relationship, Drug; Fe	1986
Suppression of DNA synthesis in NEL-M1 human melanoma cells by triamcinolone acetonide. Cancer research, 1985, Volume: 45, Issue:4 Topics: Cells, Cultured; Dihydroxyphenylalanine; DNA, Neoplasm; Humans; Melanoma; Receptors, Glucocorticoid;	1985
Differential modulation by recombinant immune interferon of the expression and shedding of HLA antigens and melanoma associated antigens by a melanoma cell line resistant to the antiproliferative activity of immune interferon. Cancer research, 1985, Volume: 45, Issue:11 Pt 2 Topics: Animals; Antigens, Neoplasm; Cell Division; Cell Line; DNA; HLA Antigens; Humans; Interferon-gamma;	1985
Antitumor activity and minimal toxicity of concentrated thymidine infused in nude mice. Cancer research, 1985, Volume: 45, Issue:4 Topics: Animals; Antineoplastic Agents; Male; Melanoma; Mice; Mice, Nude; Solubility; Thymidine; Thymine	1985
Use of growth-attachment correlation plots to analyse human melanoma cell dependency on 2-oxocarboxylates and serum. Cell and tissue kinetics, 1985, Volume: 18, Issue:4 Topics: Carbon Radioisotopes; Carboxylic Acids; Cell Adhesion; Cell Division; Cell Line; DNA Replication; Hu	1985
A novel approach to the study of kinetically changing cell populations. Cell and tissue kinetics, 1985, Volume: 18, Issue:4 Topics: Carbon Radioisotopes; Cell Cycle; Cell Division; Cell Line; DNA Replication; Humans; Kinetics; Melan	1985
Glucocorticoid receptors and cell cycle progression in human melanoma cell lines. Journal of cellular physiology, 1985, Volume: 125, Issue:2 Topics: Binding Sites; Cell Cycle; Cell Division; Cell Line; Colchicine; Dexamethasone; Flow Cytometry; Gluc	1985
Macrophage-melanoma cell heterokaryons. 3. The activation of macrophage DNA synthesis. Studies with inhibitors of protein synthesis and with synchronized melanoma cells. The Journal of experimental medicine, 1971, Oct-01, Volume: 134, Issue:4 Topics: Animals; Anti-Bacterial Agents; Cell Fusion; Cell Nucleus; Cells, Cultured; Cyclohexanes; Cyclohexim	1971
Bleomycin as a possible synchronizing agent for human tumor cells in vivo. Cancer research, 1973, Volume: 33, Issue:4 Topics: Antibiotics, Antineoplastic; Autoradiography; Biopsy; Bleomycin; Cell Division; Humans; Melanoma; Mi	1973
Proceedings: Evaluation of immune status in tumor patients. Archives of surgery (Chicago, Ill. : 1960), 1974, Volume: 108, Issue:4 Topics: Adenocarcinoma; Alpha-Globulins; B-Lymphocytes; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; C	1974
In vitro methods to complement in vivo approaches utilizing combinations of chemotherapy and immunotherapy. Cancer chemotherapy reports. Part 2, 1974, Volume: 4, Issue:1 Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Bleomycin; Carmustine; Cells, Cultured; Chickens	1974
Detection in human melanoma cell lines of particles with some properties in common with RNA tumour viruses. International journal of cancer, 1974, May-15, Volume: 13, Issue:5 Topics: Biopsy; Cell Line; Cells, Cultured; Centrifugation, Density Gradient; Cerebellar Neoplasms; DNA Nucl	1974
[Observations on radioautographic methods of in vitro study of excised tissues using H3-thymidine]. Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1967, Volume: 51 Topics: Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Nucleus; Culture Techniques; Liver; Melanom	1967
In vitro lymphocyte stimulation by a soluble antigen from malignant melanoma. The New England journal of medicine, 1970, Aug-13, Volume: 283, Issue:7 Topics: Adult; Aged; Antigens; Beta-Globulins; Blood Protein Electrophoresis; Cross Reactions; Electrophores	1970
Inhibition of DNA and protein synthesis in melanocytes by a melanoma extract. The Journal of investigative dermatology, 1974, Volume: 62, Issue:1 Topics: Animals; Carbon Radioisotopes; Catechol Oxidase; Cell Line; Cells, Cultured; Centrifugation, Density	1974
Harding-Passey melanoma in the BALB-C mouse as a model for studying the interactions between host macrophages and tumor cells. The Yale journal of biology and medicine, 1973, Volume: 46, Issue:5 Topics: Acid Phosphatase; Animals; Ascitic Fluid; Catechol Oxidase; Female; Lymphocyte Activation; Lymphocyt	1973
[On the significance of eosinophilic leukocytes in neurologic diseases]. Wiener Zeitschrift fur Nervenheilkunde und deren Grenzgebiete, 1969, Volume: 27, Issue:2 Topics: Adult; Anaphylaxis; Brain Neoplasms; Child, Preschool; Diffuse Cerebral Sclerosis of Schilder; Eosin	1969
A new model of growth regulation. Cell-specific inhibition of DNA-synthesis in HeLa-cells by endometrium extract. Die Naturwissenschaften, 1969, Volume: 56, Issue:11 Topics: Animals; Cricetinae; Depression, Chemical; DNA, Neoplasm; Endometrium; Female; Glycoproteins; Growth	1969
[Nucleic acid and protein synthesis in hamster melanoma under the influence of drugs. I. In vivo studies of DNA synthesis in hamster melanoma]. Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1970, Volume: 266, Issue:4 Topics: Acridines; Animals; Cell Nucleus; Cricetinae; DNA, Neoplasm; Melanoma; Mitochondria; Neoplasm Protei	1970
DNA synthesis in genetically determined melanomas of platyfish-swordtail hybrids. Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1973, Nov-01, Volume: 80, Issue:2 Topics: Animals; Cyprinidae; DNA, Neoplasm; Fish Diseases; Hybridization, Genetic; Melanoma; Species Specifi	1973
DNA replication and degradation in mammalian tissues. V. A series of slow-growing rat renal tumors and a variety of human cancers. Journal of the National Cancer Institute, 1969, Volume: 43, Issue:6 Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Col	1969
In vitro detection of cytotoxic cellular immunity against tumor-specific antigens by a radioisotopic technique. Proceedings of the National Academy of Sciences of the United States of America, 1971, Volume: 68, Issue:6 Topics: Adenocarcinoma; Animals; Antigen-Antibody Reactions; Antigens; Antigens, Neoplasm; Autoradiography;	1971
Lymphocyte blastogenic responses to cultured allogeneic tumor cells in vitro. Cancer research, 1972, Volume: 32, Issue:5 Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Count; Cells, Cultured; Female; Hu	1972
Response of mouse melanoma cells to melanocyte stimulating hormone. Nature, 1974, Mar-22, Volume: 248, Issue:446 Topics: Animals; Catechol Oxidase; Cell Division; Cell Line; Cyclic AMP; DNA, Neoplasm; Melanocyte-Stimulati	1974
In vitro determination of thymidine-3H labeling index in human solid tumors. Cancer research, 1974, Volume: 34, Issue:6 Topics: Autoradiography; Carcinoma, Small Cell; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm	1974
Proceedings: Studies on a nonspecific and non-cytotoxic cytostatic factor produced by macrophages. British journal of cancer, 1974, Volume: 30, Issue:2 Topics: Animals; Cytotoxicity Tests, Immunologic; Female; Macrophages; Mammary Neoplasms, Experimental; Mela	1974
Sensitisation of lymphocytes in vitro against human melanoma-associated antigens. Nature, 1974, Sep-13, Volume: 251, Issue:5471 Topics: Antigens, Neoplasm; Cell Line; Cytotoxicity Tests, Immunologic; Humans; Lymphocyte Activation; Lymph	1974
Bromodeoxyuridine dependence--a new mutation in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:1 Topics: Aminopterin; Animals; Bromodeoxyuridine; Cell Division; Cell Line; Centrifugation, Density Gradient;	1973
Antigen solubilized from human solid tumours: lymphocyte stimulation and cutaneous delayed hypersensitivity. Nature: New biology, 1973, Jun-06, Volume: 243, Issue:127 Topics: Antigens, Neoplasm; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hodgkin Disease; Humans;	1973
Total substitution of bromodeoxyuridine for thymidine in the DNA of a bromodeoxyuridine-dependent cell line. Proceedings of the National Academy of Sciences of the United States of America, 1974, Volume: 71, Issue:5 Topics: Aminopterin; Animals; Autoradiography; Bromodeoxyuridine; Cell Line; Chemical Phenomena; Chemistry;	1974
Blastogenic response of normal lymphocytes to cultured lymphoid cells and non-lymphoid neoplastic cells. Immunology, 1972, Volume: 23, Issue:3 Topics: Burkitt Lymphoma; Carcinoma; Cell Line; Cells, Cultured; Humans; Lymphocyte Activation; Lymphocytes;	1972
[In vitro-determination of the cytostatic sensitivity of malignant tumours (author's transl)]. Archiv fur klinische und experimentelle Ohren- Nasen- und Kehlkopfheilkunde, 1973, Oct-12, Volume: 204, Issue:3 Topics: Antineoplastic Agents; Autoradiography; Carcinoma, Squamous Cell; Cyclophosphamide; Diethylstilbestr	1973
[Comparative autoradiographic study on the stroma reaction in melanoma and basal cell epithelioma (author's transl)]. Archiv fur dermatologische Forschung, 1974, Volume: 250, Issue:2 Topics: Autoradiography; Carcinoma, Basal Cell; Cytological Techniques; DNA, Neoplasm; Humans; Immunity, Cel	1974
[Electron microscopy autoradiography of labelled host cells in mouse melanomas]. Archiv fur dermatologische Forschung, 1972, Volume: 245, Issue:4 Topics: Animals; Autoradiography; Eosinophils; Epithelial Cells; Fibroblasts; Histiocytes; Injections, Intra	1972
The in vivo cell kinetics of transplantable B16 mouse melanoma. Growth, 1972, Volume: 36, Issue:4 Topics: Animals; Cell Survival; DNA Replication; Kinetics; Male; Melanoma; Mice; Mice, Inbred C57BL; Mitosis	1972
Lymphocyte reactivity in cancer patients: correlation with tumor histology and clinical stage. Cancer, 1973, Volume: 31, Issue:1 Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Antilymphocyte Serum; Carcinoma; Carcinoma, Sq	1973
Correlation of preoperative lymphocyte reactivity with the clinical course of cancer patients. Surgery, gynecology & obstetrics, 1973, Volume: 136, Issue:3 Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Follow-Up Studies; H	1973
Effect of 5-bromodeoxyuridine (BUdR) on experimental metastasis. Research communications in chemical pathology and pharmacology, 1973, Volume: 5, Issue:3 Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Clone Cells; Dose-Response Relationship, Drug; Ido	1973
Immunologic effects of BCG in patients with malignant melanoma: specific evidence for stimulation of the 'secondary' immune response. Journal of the National Cancer Institute, 1973, Volume: 51, Issue:1 Topics: Adult; Antibody Formation; BCG Vaccine; Candida; Complement System Proteins; Female; Humans; Hyperse	1973
The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients. Journal of clinical pathology, 1973, Volume: 26, Issue:7 Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lectins; Leukemia; Lymph	1973
A cytokinetic model for heterogeneous mammalian cell populations. II. Tritiated thymidine studies: the per cent labeled mitosis (PLM) curve. Journal of theoretical biology, 1974, Volume: 44, Issue:1 Topics: Age Factors; Animals; Autoradiography; Carcinoma, Ehrlich Tumor; Cell Count; Cell Survival; DNA; Emb	1974
8-Azaguanine-resistant melanoma cells in vitro and in vivo. Journal of the National Cancer Institute, 1974, Volume: 52, Issue:4 Topics: Aminopterin; Animals; Azaguanine; Bromodeoxyuridine; Cell Division; Cell Fusion; Cell Line; Drug Res	1974
Inhibition of melanogenesis with 5-bromodeoxyuridine treatment in a single period of DNA synthesis. Journal of the National Cancer Institute, 1974, Volume: 52, Issue:5 Topics: Bromodeoxyuridine; Cell Differentiation; Cell Division; Cells, Cultured; Depression, Chemical; DNA;	1974
A study of cellular inflammatory reaction in human malignant melanoma, using in vitro-labelling techniques with h3-thymidine. Archiv fur dermatologische Forschung, 1974, Apr-29, Volume: 249, Issue:3 Topics: Biopsy; Connective Tissue Cells; DNA; Humans; Immunity, Active; Lymphocytes; Macrophages; Mast Cells	1974
Immune surveillance and tumor dissemination: in vitro comparison of the B16 melanoma in primary and metastatic form. Surgery, 1974, Volume: 76, Issue:1 Topics: Animals; Antigens, Neoplasm; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells; Cells, Cu	1974
The effects of cytostatic drugs on transplanted tumours. An investigation of the correlation between in vivo and in vitro results. Archiv fur Geschwulstforschung, 1974, Volume: 43, Issue:2 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Cytarabine; Dauno	1974
Suppression of malignancy and differentiation in melanotic melanoma cells. Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 66, Issue:1 Topics: Animals; Bromodeoxyuridine; Clone Cells; Culture Techniques; Melanoma; Mice; Microscopy, Phase-Contr	1970
Proliferation and differentiation of pigment cells in vitro. The Journal of investigative dermatology, 1970, Volume: 55, Issue:6 Topics: Animals; Carbon Isotopes; Cell Count; Cell Differentiation; Cell Division; Cell Line; Chromatophores	1970
[Autoradiographic investigation of whether the uptake of labeled thymidine under in vivo conditions is comparable to in vitro uptake by tissue samples]. Virchows Archiv. B, Cell pathology, 1969, Volume: 4, Issue:2 Topics: Animals; Autoradiography; Biopsy; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Humans; In Vitro Techni	1969
S91 mouse melanoma sublines following total in vitro versus alternate in vivo passages. Journal of the National Cancer Institute, 1972, Volume: 48, Issue:4 Topics: Animals; Autoradiography; Cell Line; Cells, Cultured; Dihydroxyphenylalanine; DNA, Neoplasm; Histocy	1972
Metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in human and animal tumor tissue. Cancer chemotherapy reports, 1972, Volume: 56, Issue:4 Topics: Amides; Animals; Antineoplastic Agents; Carbohydrates; Carbon Isotopes; Chromatography, Thin Layer;	1972
In vivo synchrony of solid B16 melanoma by cytosine arabinoside, an inhibitor of DNA synthesis. Journal of the National Cancer Institute, 1972, Volume: 49, Issue:4 Topics: Animals; Autoradiography; Cell Division; Cell Survival; Cytarabine; DNA; Dose-Response Relationship,	1972
Analysis of the cell kinetics of human solid tumors. Cancer, 1971, Volume: 28, Issue:5 Topics: Adult; Aged; Biopsy; Bone Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Colo	1971
Possible role of cell kinetics in prediction of the response to cancer therapy. National Cancer Institute monograph, 1971, Volume: 34 Topics: Animals; Antineoplastic Agents; Autoradiography; Drug Resistance; Humans; Mammary Neoplasms, Experim	1971
Cell kinetic analysis of a human melanoma in vitro and in vivo-vitro. Journal of the National Cancer Institute, 1971, Volume: 47, Issue:3 Topics: Adult; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Carbon Isotopes; Culture Techniques; DNA, Neo	1971
Amino acids as stimulating agents of DNA replication in melanomas. I. Stimulation in explants. Experientia, 1969, Aug-15, Volume: 25, Issue:8 Topics: Amino Acids; Animals; Autoradiography; Culture Techniques; DNA Replication; Enzyme Repression; Genes	1969
Cell proliferation in human melanoma. The Journal of clinical investigation, 1970, Volume: 49, Issue:6 Topics: Adult; Aged; Autoradiography; Biopsy; Cell Division; DNA, Neoplasm; Female; Humans; Male; Melanoma;	1970
Cytostasis of mouse and human monolayer cell cultures by normal, unstimulated lymphocytes. Journal of immunology (Baltimore, Md. : 1950), 1970, Volume: 105, Issue:1 Topics: Animals; Cell Count; Cell Line; Culture Techniques; Humans; L Cells; Lymph Nodes; Lymphocytes; Macro	1970
DNA, RNA, and protein synthesis of pigment cells in culture. The Journal of investigative dermatology, 1970, Volume: 54, Issue:6 Topics: Animals; Autoradiography; Chromatophores; Culture Techniques; DNA; Leucine; Melanins; Melanoma; Mice	1970
[Microsurgical cell nucleus transplantation in mammalian cells]. Experimental cell research, 1970, Volume: 60, Issue:3 Topics: Animals; Ascites; Autoradiography; Cell Division; Chromosomes; Culture Techniques; Histocompatibilit	1970
Experience with a mixed lymphocyte-tumor reaction as a method of detecting antigenic differences between normal and neoplastic cells. Journal of immunology (Baltimore, Md. : 1950), 1970, Volume: 105, Issue:4 Topics: Animals; Antigens; Ascitic Fluid; Culture Techniques; Lymphocytes; Lymphoma; Melanoma; Mice; Radiati	1970
[Specific cell functions of cell and tissue cultures. II. Control of melanin synthesis in cell cultures of the Harding-Passey melanoma]. Hoppe-Seyler's Zeitschrift fur physiologische Chemie, 1970, Volume: 351, Issue:11 Topics: Animals; Carbon Isotopes; Culture Techniques; Depression, Chemical; Dihydroxyphenylalanine; Leucine;	1970
[Effects of proflavine on DNA metabolism in hamster melanoma]. Archiv fur klinische und experimentelle Dermatologie, 1970, Volume: 239, Issue:2 Topics: Acridines; Animals; Antimetabolites; Cell Nucleus; Cricetinae; DNA, Neoplasm; Female; Liver; Melanom	1970
[Utilization of pyrimidine precursors in the tumor and liver of mice with Ehrlich ascites carcinoma]. Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 70, Issue:12 Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Cytosine; DNA; DNA, Neoplasm; Liver; Male; Melan	1970
Cell cycle characteristics of human solid tumors in vivo. Cell and tissue kinetics, 1970, Volume: 3, Issue:3 Topics: Biopsy; Breast Neoplasms; Cell Count; Cell Differentiation; DNA; DNA, Neoplasm; Humans; Kinetics; Me	1970
Kinetic parameters and growth curves for experimental tumor systems. Cancer chemotherapy reports, 1970, Volume: 54, Issue:3 Topics: Adenocarcinoma; Animals; Autoradiography; Benz(a)Anthracenes; Carcinoma, Ehrlich Tumor; Female; Kine	1970
[Radioautographic study of the cell cycle of a Harding-Passey melanoma in culture]. Biulleten' eksperimental'noi biologii i meditsiny, 1971, Volume: 71, Issue:4 Topics: Autoradiography; Culture Techniques; Melanoma; Mitosis; Neoplasm Transplantation; Neoplasms, Experim	1971
[3H-Thymidine incorporation into mouse and rat tissues under in vivo and in vitro conditions]. Die Naturwissenschaften, 1967, Volume: 54, Issue:19 Topics: Animals; Autoradiography; Carbon Isotopes; Cell Nucleus; In Vitro Techniques; Liver; Melanoma; Mice;	1967
Studies of leukocyte kinetics in chronic lymphocytic leukemia. Blood, 1968, Volume: 31, Issue:3 Topics: Aged; Autoradiography; Female; Humans; Injections, Intravenous; Kinetics; Leukemia, Lymphoid; Leukoc	1968
[Radiation-sensitivity of DNA synthesis and mitosis in the Harding-Passey melanoma and small intestine of the mouse. Biochemical and autoradiographic studies with radioactive thymidine]. Biophysik, 1968, May-15, Volume: 4, Issue:4 Topics: Animals; Autoradiography; Carbon Isotopes; DNA; DNA, Neoplasm; Intestine, Small; Male; Melanoma; Mic	1968
Lymphoid cellular responses in the blood after immunization in man. The Journal of experimental medicine, 1969, May-01, Volume: 129, Issue:5 Topics: Antibody Formation; Antigen-Antibody Reactions; Autoradiography; Carcinoma; DNA; Endoplasmic Reticul	1969
Amino acids as stimulating agents of DNA replication in melanomas. II. Stimulation in in-situ melanomas. Experientia, 1969, Volume: 25, Issue:7 Topics: Amino Acids; Animals; Chromatography, Ion Exchange; DNA Replication; Fishes; Melanoma; Methods; Seaw	1969

thymidine and Melanoma

Research Excerpts

Research

Studies (195)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Miran, T	1
Vogg, ATJ	1
El Moussaoui, L	1
Kaiser, HJ	1
Drude, N	1
von Felbert, V	1
Mottaghy, FM	1
Morgenroth, A	1
Gluck, I	1
Simon, AJ	1
Catane, R	1
Pfeffer, R	1
Schachter, J	1
Rechavi, G	1
Bar, J	1
Tseng, JR	1
Stuart, D	1
Aardalen, K	1
Kaplan, A	1
Aziz, N	1
Hughes, NP	1
Gambhir, SS	1
Goukassian, DA	1
Sharov, A	1
Rhodes, J	1
Coleman, C	1
Eller, MS	1
Sharova, T	1
Bhawan, J	1
Gilchrest, BA	1
Zelvyte, I	1
Sjögren, HO	1
Janciauskiene, S	1
MARAINI, G	1
FRANGUELLI, R	1
POLACK, FM	1
Tang, CH	1
Grimm, EA	2
Mahabir, S	1
Frenkel, K	1
Brady, MS	1
Coit, D	1
Leibes, L	1
Karkoszka, J	1
Berwick, M	1
Antony, S	1
Agama, KK	1
Miao, ZH	1
Hollingshead, M	1
Holbeck, SL	1
Wright, MH	1
Varticovski, L	1
Nagarajan, M	1
Morrell, A	1
Cushman, M	1
Pommier, Y	1
Pourpak, A	1
Dorr, RT	1
Meyers, RO	1
Powell, MB	1
Stratton, SP	1
Dréau, D	1
Foster, M	1
Hogg, M	1
Culberson, C	1
Nunes, P	1
Wuthier, RE	1
Stragand, JJ	1
Drewinko, B	2
Barlogie, B	1
Papadopoulous, N	1
White, RA	1
Parsons, PG	4
Musk, P	1
Goss, PD	1
Leah, J	1
Hakim, AA	2
Leyva, A	2
Appel, H	2
Pinedo, HM	2
Hill, HZ	2
Hill, GJ	2
Sokolova, IS	1
Elekes, I	1
Otvös, L	1
Gorbacheva, LB	1
Hayward, IP	1
Gill, PG	1
De Young, NJ	1
Thompson, A	1
Keightley, DD	1
Horsfall, DJ	1
Vercammen-Grandjean, A	1
Arnould, R	1
Libert, A	2
Ewalenko, P	1
Lejeune, F	1
Storm, FK	1
Roe, DJ	1
Hildebrand-Zanki, S	1
Worth, GD	1
Morton, DL	6
Kern, DH	2
DiSorbo, DM	4
Nathanson, L	4
Lockshin, A	2
Mendoza, JT	1
Giovanella, BC	4
Stehlin, JS	4
Dewey, DL	1
Holden, JL	1
Mac Neil, S	1
Walker, SW	1
Senior, HJ	1
Bleehen, SS	1
Tomlinson, S	1
McNulty, B	1
Furuse, T	1
Kasuga, T	1
Lönn, U	6
Dippenaar, N	1
Booyens, J	1
Fabbri, D	1
Katzeff, IE	1
Sheridan, JW	3
Simmons, RJ	2
Bishop, CJ	1
Lönn, S	4
Suzuki, N	1
Sekiya, S	1
Sugano, I	1
Kojima, T	1
Yamamori, H	1
Takakubo, Y	1
Richardson, DR	1
Neumannova, V	1
Ponka, P	1
Roby, P	1
Page, M	1
Piérard-Franchimont, C	1
Piérard, GE	1
Marshall, ES	2
Matthews, JH	1
Shaw, JH	1
Nixon, J	1
Tumewu, P	1
Finlay, GJ	1
Holdaway, KM	2
Baguley, BC	2
Smit, NP	1
Latter, AJ	1
Naish-Byfield, S	1
Westerhof, W	1
Pavel, S	1
Riley, PA	1
Kirshenbaum, MR	1
Chen, SF	1
Behrens, CH	1
Papp, LM	1
Stafford, MM	1
Sun, JH	1
Behrens, DL	1
Fredericks, JR	1
Polkus, ST	1
Sipple, P	1
Fuchsberger, N	1
Kubes, M	1
Kontsek, P	1
Borecký, L	1
Hornák, M	1
Godál, A	1
Svec, J	1
Pettersson, OA	1
Olsson, P	1
Lindström, P	1
Sjöberg, S	1
Carlsson, J	1
Süli-Vargha, H	1
Ghanem, G	1
Morandini, R	1
Botyánszki, J	1
Medzihradszky, K	1
Takeyama, H	1
Hoon, DS	1
Saxton, RE	1
Irie, RF	1
Muthukkumar, S	1
Sells, SF	1
Crist, SA	1
Rangnekar, VM	2
Kikuchi, K	1
Nakagawa, H	1
Kadono, T	1
Etoh, T	1
Byers, HR	1
Mihm, MC	1
Tamaki, K	1
Clavo, AC	1
Wahl, RL	1
Nakayama, J	1
Nakao, T	1
Mashino, T	1
Nagae, S	1
Hori, Y	1
Mayumi, H	1
Tominaga, R	1
Yasui, H	1
Matsuda, K	1
Takahashi, S	1
Chakraborty, AK	1
Sodi, S	1
Rachkovsky, M	1
Kolesnikova, N	1
Platt, JT	1
Bolognia, JL	1
Pawelek, JM	1
Abbas Rizvi, SM	1
Sarkar, S	1
Goozee, G	1
Allen, BJ	1
Parmar, J	1
Charters, GA	1
Shelling, AN	1
Yu, D	1
Thomas-Tikhonenko, A	1
Wellbrock, C	1
Weisser, C	1
Geissinger, E	1
Troppmair, J	1
Schartl, M	1
Nouman, GS	1
Angus, B	1
Lunec, J	1
Crosier, S	1
Lodge, A	1
Anderson, JJ	1
Pees, HW	1
Wayss, K	4
Mattern, J	3
Volm, M	4
Golub, SH	2
Sulit, HL	1
Faufmann, M	1
Kreider, JW	3
Wade, DR	1
Rosenthal, M	2
Densley, T	1
Wick, MM	2
Bertino, JR	1
Lee, SS	2
Brunn, JC	1
Howell, SB	1
Jenkins, RS	1
Streifel, J	1
Fischer, PH	1
Lin, TS	1
Chen, MS	1
Prusoff, WH	1
Kaufman, ER	2
Davidson, RL	4
Wiskemann, A	1
Schussmann, M	1
Rothmann, D	1
Schneider, O	1
Bobo, B	1
Lui, VK	1
Dent, PB	2
Liao, SK	2
Ettin, G	1
Cleland, GB	1
Silagi, S	2
Balint, RF	1
Gauri, KK	1
Roth, JA	1
Thirlwell, MP	1
Livingston, RB	2
Murphy, WK	1
Hart, JS	2
Goncharova, SA	1
Vasil'eva, LS	1
Shevtsova, VN	1
Konovalova, NP	1
Tolkacheva, EN	1
Savvateeva, ZhP	1
Agranat, VZ	1
Young, RC	3
Rosenoer, VM	1
Curby, WA	1
Norbury, KC	1
Fidler, IJ	1
Brereton, HD	1
Bryant, TL	1
Schneider, WC	1
Shelton, E	1
Kuff, EL	1
Sato, C	1
Banks, J	1
Garlick, S	1
Davidson, EA	1
Lavin, M	1
Chalmers, AH	1
Kidson, C	1
Apfel, R	2
Lottspeich, F	1
Hoppe, J	2
Behl, C	2
Dürr, G	1
Bogdahn, U	2
Supino, R	1
Mapelli, E	1
Sanfilippo, O	1
Silvestro, L	1
Rangnekar, VV	1
Waheed, S	1
Lee, JD	1
Sievers, TM	1
Skotzko, M	1
Chandler, CF	1
McBride, WH	1
Economou, JS	1
Lu, C	1
Vickers, MF	1
Kerbel, RS	1
Sánchez-Gómez, MV	1
Conde-Guerri, B	1
Sinués-Porta, E	1
Matute, C	1
Shultz, TD	1
Chew, BP	1
Seaman, WR	1
Luedecke, LO	1
Shieh, HL	1
Pezzuto, JM	1
Cordell, GA	1
Thomas, HG	3
Han, JH	1
Balentien, E	1
Derynck, R	1
Bordoni, R	1
Richmond, A	3
Cheng, FM	1
Hansen, EB	1
Taylor, CR	1
Epstein, AL	1
Neefe, JR	1
Glass, J	1
Kidson, SH	1
De Haan, JB	1
Matsushima, H	1
Bogenmann, E	1
Costa, A	2
Silvestrini, R	2
Mezzanotte, G	1
Vaglini, M	1
Grignolio, E	2
Clemente, C	2
Cascinelli, N	1
Morinaga, Y	1
Hayashi, H	1
Takeuchi, A	1
Onozaki, K	1
Fischel, JL	1
Formento, P	1
Etienne, MC	1
Gioanni, J	1
Frenay, M	1
Deloffre, P	1
Bizzari, JP	1
Milano, G	1
Sondak, VK	1
Hildebrand-Zanki, SU	1
Butler, A	1
Nylen, U	2
Winblad, G	2
Sullivan, JL	1
Sullivan, LG	1
Hahn, M	1
Gerlach, M	1
Martin, R	1
McGarvey, TW	1
Persky, B	1
Hansson, J	1
Lewensohn, R	1
Ringborg, U	1
Branda, RF	1
McCormack, JJ	1
Perlmutter, CA	1
Roy, RG	2
Barsky, SH	1
Gopalakrishna, R	1
Lawson, DH	1
Gordon, DS	1
Chawla, RK	1
Nixon, DW	1
Attili, A	1
Testori, A	1
Natuk, RJ	1
Byrne, JA	1
Holowczak, JA	1
Sipes, NJ	1
Meyskens, FL	1
Bregman, MD	1
Lea, MA	1
Luke, A	1
Velazquez, O	1
Carpenter, L	1
Martinson, CF	1
Erba, E	1
Pepe, S	1
Ubezio, P	1
Lorico, A	1
Morasca, L	1
Mangioni, C	1
Landoni, F	1
D'Incalci, M	1
Ashman, CR	1
Harris, NA	1
Ziai, MR	1
Imberti, L	1
Tongson, A	1
Ferrone, S	1
Kozielski, T	1
Quian, C	1
Apperson, RW	1
Kay, GF	1
Ellem, KA	1
Osman, AM	1
Jansen, PW	1
Smets, LA	1
Benckhuijsen, C	1
Gordon, S	1
Cohn, Z	1
McKhann, CF	2
Jagarlamoody, SM	2
Barranco, SC	1
Luce, JK	2
Romsdahl, MM	1
Humphrey, RM	1
Vetto, RM	1
Burger, DR	1
Lilley, DP	1
Sigel, MM	1
Lichter, W	1
Lopez, DM	1
Goss, P	1
Pope, JH	1
Helpap, B	3
Maurer, W	3
Jehn, UW	1
Schwartz, RS	1
Skinner, M	1
Seiji, M	1
Nakano, H	1
Akiba, H	1
Kato, T	1
Lejeune, FJ	2
Kolár, O	1
Zeman, W	1
Ciembroniewicz, J	1
Veselý, F	1
Hinderer, H	1
Balda, BR	2
Birkmayer, G	1
Vielkind, J	1
Vielkind, U	1
Anders, F	3
Laszlo, J	1
Ove, P	1
Shingleton, WW	1
Morris, HP	1
Aust, JC	1
Tew, RH	1
Anderson, RJ	1
McBride, CM	2
Hersh, EM	2
Wong, G	1
Pawelek, J	1
Sansone, M	1
Morowitz, J	1
Ambus, U	2
George, SL	1
Freireich, EJ	1
Reginier, R	1
Bick, MD	2
Mavligit, GM	1
Gutterman, JU	1
Han, T	1
Stiller, KJ	1
Löbe, LP	1
Pullmann, H	2
Steigleder, GK	2
Dvorák, R	1
Eckhardt, U	1
Gibson, MH	2
Bertalanffy, FD	2
Catalona, WJ	2
Sample, WF	2
Chretien, PB	2
Crowder, WL	1
Gertner, HR	1
Zeidman, I	1
Chess, L	1
Bock, GN	1
Ungaro, PC	1
Buchholz, DH	1
Mardiney, MR	2
Kumar, S	1
Taylor, G	1
Shackney, SE	1
Pasztor, LM	1
Hu, F	3
Stankova, L	1
Bigley, R	1
Matheson, DW	1
Beltz, B	1
Goldman, LI	1
Flaxman, BA	1
Wernick, G	1
Zabriskie, JB	1
Bruce, SA	1
Kitano, Y	2
Creasey, WA	1
Capizzi, RL	1
DeConti, RC	1
Cobb, JP	1
McGrath, A	1
Mizuno, NS	1
Humphrey, EW	1
Terz, JJ	1
Curutchet, HP	1
Lawrence, W	1
Tannock, I	2
Frei, E	2
Hagemann, RF	1
Schiffer, LM	1
Sieger, M	2
Klinke, K	1
Shirakawa, S	1
Jamieson, CW	1
Wallace, JH	1
Grässman, A	1
Kanner, SP	1
Mangi, RJ	1
Schachtschabel, D	1
Fischer, RD	1
Zilliken, F	1
Birkmayer, GD	1
Fedorov, NA	1
Matveenko, VN	1
Tikhonova, EF	1
DeVita, VT	1
Simpson-Herren, L	1
Lloyd, HH	1
Terent'eva, TG	1
Radzievskaia, VV	1
Gibadulin, RA	1
Zimmerman, TS	1
Godwin, HA	1
Perry, S	1
Hempel, K	1
Crowther, D	1
Fairley, GH	1
Sewell, RL	1
Sieger, F	1
Prüssing, R	1