Page last updated: 2024-11-06

thymidine and Malaria

thymidine has been researched along with Malaria in 17 studies

Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.

Research Excerpts

ExcerptRelevanceReference
" None of the dosing regimens caused toxicological manifestations other than hepatomegaly."1.27Alteration of bone marrow cell cycle kinetics by diphenylhydantoin: relationship to folate utilization and immune function. ( Boorman, GA; Hong, L; Luster, MI; Pung, O; Tucker, AN, 1985)
"The thymidine was incorporated by non-adherent spleen cells in a single pulse during the first 8 hr in culture."1.25Dynamics of thymidine incorporation by spleen cells from rats infected with Plasmodium berghei. ( Golenser, J; Spira, DT; Zuckerman, A, 1975)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-199016 (94.12)18.7374
1990's1 (5.88)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Troye-Blomberg, M4
Perlmann, H3
Patarroyo, ME3
Perlmann, P4
Romero, P1
Björkman, A1
Sjöholm, PE1
Frankenburg, S1
Greenblatt, CL1
Golenser, J2
Spira, DT2
Zuckerman, A1
Riley, EM1
Kabilan, L1
Holmberg, M1
Andersson, U1
Heusser, CH1
Bygbjerg, IC1
Jepsen, S1
Theander, TG1
Odum, N1
Tucker, AN1
Hong, L1
Boorman, GA1
Pung, O1
Luster, MI1
Greenwood, BM1
Bradley-Moore, AM1
Bryceson, AD1
Palit, A1
Conklin, KA1
Chou, SC1
Siddiqui, WA1
Schnell, JV1
Moore, DL1
Heyworth, B1
Brown, J1
Moran, CJ1
De Rivera, VS1
Turk, JL1
Jacobs, RL1
Miller, LH1
Koontz, LC1
Rubini, JR1
Matsui, K1
Rane, L1
Phillips, RS1
Wolstencroft, RA1
Brown, IN1
Brown, KN1
Dumonde, DC1
Büngener, W1
Nielsen, G1
Sullivan, LW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Markers of T Cell Suppression: Antimalarial Treatment and Vaccine Responses in Healthy Malian Adults[NCT02544048]49 participants (Actual)Observational2015-09-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

17 other studies available for thymidine and Malaria

ArticleYear
Regulation of the immune response in Plasmodium falciparum malaria. II. Antigen specific proliferative responses in vitro.
    Clinical and experimental immunology, 1983, Volume: 53, Issue:2

    Topics: Acute Disease; DNA; Epitopes; Humans; Immunity, Cellular; Lymphocyte Activation; Lymphocytes; Malari

1983
Regulation of the immune response in Plasmodium falciparum malaria. III. Proliferative response to antigen in vitro and subset composition of T cells from patients with acute infection or from immune donors.
    Clinical and experimental immunology, 1984, Volume: 58, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, Protozoan; Antigens, Surface; Cell Division; Cells, Cultured; Epit

1984
Regulation of the immune response in Plasmodium falciparum malaria. I. Non-specific proliferative responses in vitro and characterization of lymphocytes.
    Clinical and experimental immunology, 1983, Volume: 53, Issue:2

    Topics: Acute Disease; Antibodies, Monoclonal; Antigens, Surface; DNA; Histocompatibility Antigens Class II;

1983
Plasmodium berghei: relationship between mitosis and erythropoiesis in spleen cells of infected rats.
    Experimental parasitology, 1977, Volume: 43, Issue:2

    Topics: Animals; DNA; Erythropoiesis; Iron; Malaria; Mitosis; Polycythemia; Rats; Spleen; Thymidine

1977
Dynamics of thymidine incorporation by spleen cells from rats infected with Plasmodium berghei.
    Clinical and experimental immunology, 1975, Volume: 22, Issue:2

    Topics: Animals; Cell Adhesion; In Vitro Techniques; Lectins; Lymphocyte Activation; Malaria; Male; Plasmodi

1975
Production by activated human T cells of interleukin 4 but not interferon-gamma is associated with elevated levels of serum antibodies to activating malaria antigens.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:14

    Topics: Adult; Amino Acid Sequence; Animals; Antibodies, Protozoan; Antibody Formation; Antigens, Protozoan;

1990
Specific proliferative response of human lymphocytes to purified soluble antigens from Plasmodium falciparum in vitro cultures and to antigens from malaria patients' sera.
    Clinical and experimental immunology, 1985, Volume: 59, Issue:2

    Topics: Adult; Antigens, Protozoan; Cells, Cultured; Female; Humans; Immunoglobulin G; Lymphocyte Activation

1985
Alteration of bone marrow cell cycle kinetics by diphenylhydantoin: relationship to folate utilization and immune function.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:1

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Cycle; Female; Folic Acid; Hematopoietic Stem Cells; I

1985
Immunosuppression in children with malaria.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Acute Disease; Animals; Antibody Formation; Antigens; Burkitt Lymphoma; Candida; Child; Disease Mode

1972
DNA and RNA syntheses by intraerythrocytic stages of Plasmodium knowlesi.
    The Journal of protozoology, 1973, Volume: 20, Issue:5

    Topics: Adenosine; Animals; Carbon Radioisotopes; Cell Count; DNA; Erythrocytes; Haplorhini; Macaca; Malaria

1973
PHA-induced lymphocyte transformations in leucocyte cultures from malarious, malnourished and control Gambian children.
    Clinical and experimental immunology, 1974, Volume: 17, Issue:4

    Topics: Child, Preschool; Dose-Response Relationship, Drug; Gambia; Granulocytes; Humans; Infant; Kwashiorko

1974
The immunological significance of histological changes in the spleen and liver in mouse malaria.
    Clinical and experimental immunology, 1973, Volume: 13, Issue:3

    Topics: Animals; Antibody Formation; Antibody-Producing Cells; Antigen-Antibody Complex; Arteries; Autoradio

1973
Labeling of sporozoites of Plasmodium berghei with tritiated purines.
    The Journal of parasitology, 1974, Volume: 60, Issue:2

    Topics: Adenine; Adenosine; Animals; Anopheles; Blood; Deoxyadenosines; Deoxyribonucleosides; Guanosine; Iso

1974
Blood proliferocytes in human and animal malaria.
    Acta haematologica, 1969, Volume: 42, Issue:3

    Topics: Animals; Autoradiography; Cell Division; Humans; Leukocytes; Lymphocytes; Malaria; Male; Mice; Monoc

1969
Immunity to malaria. 3. Possible occurrence of a cell-mediated immunity to Plasmodium knowlesi in chronically infected and Freund's complete adjuvant-sensitized monkeys.
    Experimental parasitology, 1970, Volume: 28, Issue:2

    Topics: Animals; Antibody Formation; Chromium; Chromium Isotopes; Culture Media; Disease Models, Animal; DNA

1970
[Nucleic acid metabolism in experimental malaria. 1. Studies on the incorporation of thymidine, uridine, and adenosine in the malaria parasite (Plasmodium berghei and Plasmodium vinckei)].
    Zeitschrift fur Tropenmedizin und Parasitologie, 1967, Volume: 18, Issue:4

    Topics: Animals; Autoradiography; Leucine; Leukocytes; Lysine; Malaria; Mice; Nucleosides; Plasmodium; Rats;

1967
Of men, malaria and megaloblasts.
    The New England journal of medicine, 1969, Jun-12, Volume: 280, Issue:24

    Topics: Anemia, Macrocytic; Bone Marrow Diseases; Folic Acid Antagonists; Humans; Malaria; Pyrimethamine; Th

1969