thymidine has been researched along with Lupus Erythematosus, Systemic in 47 studies
Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of heat-aggregated human gamma globulin (aggFII) on the induction of in vitro lymphocyte transformation, measured by the uptake of tritiated thymidine into newly synthesized DNA, was studied with peripheral blood lymphocytes derived from 12 patients with rheumatoid arthritis (RA), six with ankylosing spondylitis (AS), two with systemic lupus erythematosus (SLE), and seven normal subjects." | 3.65 | Enhancement of human lymphocyte transformation by aggregated human gamma globulin. ( Kinsella, TD, 1974) |
| "Systemic lupus erythematosus is an autoimmune disease primarily affecting women." | 1.32 | Interactions of prednisolone and other immunosuppressants used in dual treatment of systemic lupus erythematosus in lymphocyte proliferation assays. ( Jusko, WJ; Kamal, MA, 2004) |
| "Prominent among them is systemic lupus erythematosus (SLE)." | 1.29 | Recognition of oxidized DNA bases by sera of patients with inflammatory diseases. ( Frenkel, K; Karkoszka, J; Kim, E; Taioli, E, 1993) |
| "3H-Thymidine incorporation was used to examine the effects of the serum of an SLE patient with multiple DFs on fibroblasts derived from DF and normal skin." | 1.29 | Involvement of basic fibroblast growth factor in fibroblast-stimulatory serum activity of a patient with systemic lupus erythematosus and multiple dermatofibromas. ( Katayama, I; Nishioka, K; Yamamoto, T, 1995) |
| "The in vitro immune response of systemic lupus erythematosus (SLE) lymphocytes to nucleosides conjugated to keyhole limpet hemocyanin (KLH) (A,G,C,T-KLH) was investigated." | 1.27 | In vitro nucleoside specific immune response by lymphocytes from systemic lupus erythematosus. ( Borel, Y; Morimoto, C; Schlossman, SF; Steinberg, AD, 1983) |
| "In contrast with this, patients with aplastic anaemia have been found to have entirely normal lymphoid cell populations in the peripheral blood and provide no evidence that this condition has an autoimmune basis." | 1.25 | Reactive lymphoid cells ('Immunoblasts') in autoimmune and haematological disorders. ( Bacon, PA; Crowther, D; Sewell, RL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (76.60) | 18.7374 |
| 1990's | 6 (12.77) | 18.2507 |
| 2000's | 5 (10.64) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| COOPER, IA | 1 |
| FIRKIN, BG | 1 |
| Kamal, MA | 1 |
| Jusko, WJ | 1 |
| Miyazaki, K | 1 |
| Takeda, N | 1 |
| Ishimaru, N | 1 |
| Omotehara, F | 1 |
| Arakaki, R | 1 |
| Hayashi, Y | 1 |
| Lin, CH | 1 |
| Wang, SC | 1 |
| Ou, TT | 1 |
| Li, RN | 1 |
| Tsai, WC | 1 |
| Liu, HW | 1 |
| Yen, JH | 1 |
| Morimoto, C | 1 |
| Steinberg, AD | 1 |
| Schlossman, SF | 1 |
| Borel, Y | 2 |
| Yamada, A | 1 |
| Winfield, JB | 1 |
| Wadee, AA | 2 |
| Gear, AJ | 1 |
| Rabson, AR | 2 |
| Dubroff, LM | 1 |
| Reid, R | 1 |
| Papalian, M | 1 |
| Diezel, W | 1 |
| Günther, W | 1 |
| Meffert, H | 1 |
| Sönnichsen, N | 1 |
| Fiorilli, M | 1 |
| Sirianni, MC | 1 |
| Pandolfi, F | 1 |
| Pucillo, LP | 1 |
| Letta, T | 1 |
| Aiuti, F | 1 |
| Frenkel, K | 1 |
| Karkoszka, J | 1 |
| Kim, E | 1 |
| Taioli, E | 1 |
| Yamamoto, T | 1 |
| Katayama, I | 1 |
| Nishioka, K | 1 |
| Harigai, M | 1 |
| Hara, M | 1 |
| Fukasawa, C | 1 |
| Nakazawa, S | 1 |
| Kawaguchi, Y | 1 |
| Kamatani, N | 1 |
| Kashiwazaki, S | 1 |
| Andreassen, K | 1 |
| Bredholt, G | 1 |
| Moens, U | 1 |
| Bendiksen, S | 1 |
| Kauric, G | 1 |
| Rekvig, OP | 1 |
| Sun, KH | 2 |
| Yu, CL | 3 |
| Tang, SJ | 1 |
| Sun, GH | 1 |
| Tsai, CY | 2 |
| Wu, TH | 1 |
| Lu, JY | 1 |
| Lair, TS | 1 |
| Tsai, YY | 1 |
| Chou, CT | 1 |
| Alarcón-Segovia, D | 1 |
| Fishbein, E | 1 |
| García-Ortigoza, E | 1 |
| Estrada-Parra, S | 1 |
| Brentjens, JR | 1 |
| Sepulveda, M | 1 |
| Baliah, T | 1 |
| Bentzel, C | 1 |
| Erlanger, BF | 1 |
| Elwood, C | 1 |
| Montes, M | 1 |
| Hsu, KC | 1 |
| Andres, GA | 1 |
| Malavé, I | 1 |
| Layrisse, Z | 1 |
| Layrisse, M | 1 |
| Beighlie, DJ | 1 |
| Teplitz, RL | 1 |
| Bacon, PA | 1 |
| Sewell, RL | 1 |
| Crowther, D | 1 |
| Liu, WT | 1 |
| Liao, TS | 1 |
| Lin, WM | 1 |
| Hashimoto, C | 1 |
| Naiki, M | 1 |
| Imai, Y | 1 |
| Osawa, T | 1 |
| Phillips, R | 1 |
| Lomnitzer, R | 1 |
| Crow, MK | 1 |
| Golan, DT | 1 |
| Djeu, JY | 1 |
| Kasahara, T | 1 |
| Balow, JE | 1 |
| Tsokos, GC | 1 |
| Yano, K | 1 |
| Morimasa, K | 1 |
| Asano, T | 1 |
| Shinohara, Y | 1 |
| Ota, Z | 1 |
| Kinsella, TD | 1 |
| Buckley, CE | 1 |
| Handin, RI | 1 |
| Piessens, WF | 1 |
| Moloney, WC | 1 |
| Suciu-Foca, N | 1 |
| Buda, JA | 1 |
| Thiem, T | 1 |
| Reemtsma, K | 1 |
| Lewis, RM | 1 |
| Stollar, BD | 1 |
| Hahn, BH | 1 |
| Bagby, MK | 1 |
| Osterland, CK | 1 |
| Mellbye, OJ | 1 |
| Lindström, FD | 1 |
| Eberle, BJ | 1 |
| Williams, RC | 1 |
| Koffler, D | 1 |
| Agnello, V | 1 |
| Winchester, R | 1 |
| Kunkel, HG | 1 |
| Bach, JF | 1 |
| Dardenne, M | 1 |
| Baló-Banga, JM | 1 |
| Pintér, E | 1 |
| Garzó, T | 1 |
| von Maur, K | 1 |
| Rocklin, RE | 1 |
| Stevens, MB | 1 |
| Denman, AM | 1 |
| Denman, EJ | 1 |
| Horwitz, DA | 2 |
| Beglarian, AG | 1 |
| Mkrtchian, LN | 1 |
| Stastny, P | 1 |
| Ziff, M | 1 |
| Fichtelius, KE | 1 |
| Groth, O | 1 |
| Lidén, S | 1 |
| Takasugi, K | 1 |
| Hollingsworth, JW | 1 |
| Pincus, T | 1 |
| Schur, PH | 1 |
| Rose, JA | 1 |
| Decker, JL | 1 |
| Talal, N | 1 |
47 other studies available for thymidine and Lupus Erythematosus, Systemic
| Article | Year |
|---|---|
DEOXYRIBONUCLEIC ACID SYNTHESIZING CELLS IN THE PERIPHERAL BLOOD OF PATIENTS WITH "AUTO-IMMUNE" DISORDERS.
Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Rheumatoid; Autoimmune Diseases; | 1965 |
Interactions of prednisolone and other immunosuppressants used in dual treatment of systemic lupus erythematosus in lymphocyte proliferation assays.
Topics: Adult; Anti-Inflammatory Agents; Cell Proliferation; Drug Interactions; Drug Therapy, Combination; F | 2004 |
Analysis of in vivo role of alpha-fodrin autoantigen in primary Sjogren's syndrome.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Apoptosis; Arthritis, Rheumatoid; Autoantigens; Blottin | 2005 |
I kappa B alpha promoter polymorphisms in patients with systemic lupus erythematosus.
Topics: Adult; Female; Genetic Predisposition to Disease; Genotype; Humans; I-kappa B Proteins; Lupus Erythe | 2008 |
In vitro nucleoside specific immune response by lymphocytes from systemic lupus erythematosus.
Topics: Adenosine; Antibody Specificity; Antigens; Cell Division; Cells, Cultured; Cytidine; gamma-Globulins | 1983 |
Inhibition of soluble antigen-induced T cell proliferation by warm-reactive antibodies to activated T cells in systemic lupus erythematosus.
Topics: Antibodies, Monoclonal; Antigens, Surface; Antilymphocyte Serum; Arthritis, Rheumatoid; Binding, Com | 1984 |
Production of a suppressor factor by human adherent cells treated with Mycobacterium tuberculosis: absence in systemic lupus erythematosus.
Topics: Adolescent; Adult; Antigen-Antibody Complex; Humans; Lupus Erythematosus, Systemic; Lymphocyte Activ | 1981 |
Molecular models for hydralazine-related systemic lupus erythematosus.
Topics: Antibodies, Antinuclear; Chromatin; DNA; Histones; Humans; Hydralazine; Lupus Erythematosus, Systemi | 1981 |
Polyclonal B cell activation in the acute phase of systemic lupus erythematosus--aspects of pathogenic significance.
Topics: B-Lymphocytes; Female; Humans; In Vitro Techniques; Lupus Erythematosus, Systemic; Lymphocyte Activa | 1982 |
Enhancement by TP-1, a thymic extract, of pokeweed mitogen-induced differentiation of B cells from normal subjects but not of those from patients with systemic lupus erythematosus.
Topics: Animals; B-Lymphocytes; Cattle; Cell Differentiation; Humans; Lupus Erythematosus, Systemic; Lymphoc | 1982 |
Recognition of oxidized DNA bases by sera of patients with inflammatory diseases.
Topics: Adult; Aged; Aging; Antibodies, Antinuclear; Antigens; Autoantibodies; DNA; Female; Humans; Lupus Er | 1993 |
Involvement of basic fibroblast growth factor in fibroblast-stimulatory serum activity of a patient with systemic lupus erythematosus and multiple dermatofibromas.
Topics: Adult; Antibodies; Becaplermin; Case-Control Studies; Cell Count; Cell Division; Cells, Cultured; Do | 1995 |
Responsiveness of peripheral blood B cells to recombinant CD40 ligand in patients with systemic lupus erythematosus.
Topics: Autoantibodies; B-Lymphocytes; Case-Control Studies; CD40 Antigens; CD40 Ligand; DNA; Humans; In Vit | 1999 |
T cell lines specific for polyomavirus T-antigen recognize T-antigen complexed with nucleosomes: a molecular basis for anti-DNA antibody production.
Topics: Adult; Antibodies, Antinuclear; Antigens, Polyomavirus Transforming; B-Lymphocytes; CD4-Positive T-L | 1999 |
Monoclonal anti-double-stranded DNA autoantibody stimulates the expression and release of IL-1beta, IL-6, IL-8, IL-10 and TNF-alpha from normal human mononuclear cells involving in the lupus pathogenesis.
Topics: Animals; Antibodies, Antinuclear; Cells, Cultured; Cytokines; Enzyme-Linked Immunosorbent Assay; Glo | 2000 |
Polyclonal anticardiolipin antibodies purified from sera of patients with active systemic lupus erythematosus induce apoptosis of the cultured glomerular mesangial cells.
Topics: Animals; Antibodies, Anticardiolipin; Apoptosis; Cells, Cultured; Gene Expression; Glomerular Mesang | 2000 |
Uracil-specific anti-R.N.A. antibodies in scleroderma.
Topics: Adenosine; Adenosine Monophosphate; Animals; Antibodies; Cattle; Cross Reactions; Cytidine; Cytosine | 1975 |
Interstitial immune complex nephritis in patients with systemic lupus erythematosus.
Topics: Antibodies; Basement Membrane; Complement System Proteins; Cytosine; DNA; Fluorescent Antibody Techn | 1975 |
Dose-dependent hyporreactivity to phytohemagglutinin in systemic lupus erythematosus.
Topics: Antibodies; Cells, Cultured; Cytotoxicity Tests, Immunologic; Humans; Lectins; Lupus Erythematosus, | 1975 |
Repair of UV damaged DNA in systemic lupus erythematosus.
Topics: Adult; Animals; Autoradiography; Breeding; Bromodeoxyuridine; Disease Models, Animal; DNA; Fibroblas | 1975 |
Reactive lymphoid cells ('Immunoblasts') in autoimmune and haematological disorders.
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Leukocyte Count; Lupus Erythem | 1975 |
Inhibition of astrocyte proliferation and binding to brain tissue of anticardiolipin antibodies purified from lupus serum.
Topics: Animals; Astrocytes; Autoantibodies; Brain; Brain Chemistry; Cardiolipins; Cell Division; Cells, Cul | 1992 |
Studies on synthesis of interleukin-6 and gammaglobulin in peripheral blood mononuclear cells of patients with systemic lupus erythematosus.
Topics: Adult; B-Lymphocytes; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; gamma-Globulins; Hu | 1990 |
Establishment of a nucleoside-specific suppressor T cell line from SLE prone (NZB/NZW)F1 mice.
Topics: Adenosine; Animals; Antibody Formation; Cell Line; Cross Reactions; Crosses, Genetic; Cytidine; Epit | 1985 |
Defective monocyte function in patients with systemic lupus erythematosus.
Topics: Blood Bactericidal Activity; Candida albicans; Cell Adhesion; Female; Glycolysis; Humans; Lupus Eryt | 1985 |
Enhancement of the impaired autologous mixed leukocyte reaction in patients with systemic lupus erythematosus.
Topics: Adult; Cell Division; Female; Formaldehyde; Histocompatibility Antigens Class II; Humans; Lupus Eryt | 1985 |
Exposure to UV light in the pathogenesis of systemic lupus erythematosus (SLE).
Topics: Animals; Antibodies, Antinuclear; Antibody Formation; Antigen-Antibody Complex; Autoantibodies; DNA; | 1988 |
Decreased interleukin 2 inhibitor in sera of patients with autoimmune disorders.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Chromatography, Gel; Hot Temperature; Humans; Lupus Eryt | 1986 |
Characterization of the spontaneous DNA-synthesizing and/or IgG-secreting cells in peripheral blood from patients with systemic lupus erythematosus.
Topics: Antibody Formation; Antibody-Producing Cells; B-Lymphocytes; Cell Separation; Cells, Cultured; DNA; | 1985 |
Enhancement of human lymphocyte transformation by aggregated human gamma globulin.
Topics: Animals; Arthritis, Rheumatoid; Cattle; Complement System Proteins; DNA; gamma-Globulins; Hot Temper | 1974 |
Anergy, dysimmunoglobulinemia, and unexplained inflammation. A new therapeutic approach with a chemically defined diet.
Topics: Adolescent; Antibody Formation; Arthus Reaction; Autoantibodies; Barbiturates; Blood Group Antigens; | 1969 |
Stimulation of nonimmunized lymphocytes by platelet-antibody complexes in idiopathic thrombocytopenic purpura.
Topics: Antibodies; Antigen-Antibody Complex; Autoantibodies; Blood Cell Count; Blood Platelets; Chromatogra | 1973 |
Impaired responsiveness of lymphocytes in patients with systemic lupus erythematosus.
Topics: Adult; Aged; Antibodies; Antigen-Antibody Reactions; Binding Sites, Antibody; HLA Antigens; Humans; | 1974 |
Prevention of murine lupus nephritis by carrier-dependent induction of immunologic tolerance to denatured DNA.
Topics: Adenosine; Age Factors; Animals; Antibodies, Antinuclear; Antibody Formation; Carrier Proteins; Cyto | 1973 |
Disparity between humoral and cellular immune responses to desoxyribonucleic acid in systemic lupus erythematosus.
Topics: Animals; Antibodies; Antibodies, Anti-Idiotypic; Antibody Formation; Antigen-Antibody Complex; Bindi | 1973 |
Reactivity of RA and SLE lymphocytes stimulated by anti-Ig antibodies.
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Female; Fluores | 1973 |
The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases.
Topics: Adenosine; Animals; Antigen-Antibody Complex; Antigens; Arthritis, Rheumatoid; Cattle; DNA; DNA, Sin | 1973 |
[Absence of thymus hormone in the serum of NZB and NZBXNZW mice and patients with systemic lupus erythematosus].
Topics: Adolescent; Adult; Animals; Azathioprine; Female; Humans; Hybridization, Genetic; Immune Adherence R | 1972 |
[Incorporation of radio-active thymidine into lymphocyte cultures].
Topics: Autoradiography; Cells, Cultured; Humans; Immunosuppressive Agents; Lectins; Lupus Erythematosus, Sy | 1973 |
Corticosteroid allergy in a patient with systemic lupus erythematosus.
Topics: Adrenal Cortex Hormones; Arthritis; Biopsy; Conjunctivitis; Dermatitis; Dexamethasone; DNA; Drug Hyp | 1974 |
Depletion of long-lived lymphocytes in old New Zealand black mice.
Topics: Aging; Anemia, Hemolytic, Autoimmune; Animals; Antilymphocyte Serum; Autoimmune Diseases; Bone Marro | 1970 |
The development of macrophages from large mononuclear cells in the blood of patients with inflammatory disease.
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Autoradiography; Cell Differentiation; Cells, Cultured; | 1972 |
[Significance of nucleic acids and nucleoproteids in the pathogenesis of systemic progressive disorganization of connective tissue].
Topics: Aminobenzoates; Animals; Autoimmune Diseases; Collagen Diseases; Heart Valve Diseases; Kidney Glomer | 1969 |
Circulating deoxyribonucleic acid--synthesizing mononuclear leukocytes. I. Increased numbers of proliferating mononuclear leukocytes in inflammatory disease.
Topics: Acute Disease; Adult; Agammaglobulinemia; Arthritis, Rheumatoid; Aspartate Aminotransferases; Autora | 1970 |
The skin, a first level lymphoid organ?
Topics: Animals; Antigens; Biological Evolution; Bursa of Fabricius; Ear, External; Epithelium; Exocrine Gla | 1970 |
Incorporation of tritiated thymidine into mononuclear cells of human synovial effusions.
Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Autoradiography; DNA; Gout; Humans; Joint Dis | 1968 |
Measurement of serum DNA-binding activity in systemic lupus erythematosus.
Topics: Adolescent; Aged; Antigen-Antibody Reactions; Autoantibodies; Carbon Isotopes; Chemical Precipitatio | 1969 |