thymidine has been researched along with Liver Neoplasms in 323 studies
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "beta-L-Thymidine (L-dT) and beta-L-2'-deoxycytidine (L-dC) are potent and highly specific inhibitors of hepatitis B virus (HBV) replication both in vivo and in vitro (50% effective concentrations, 0." | 7.71 | Pharmacology of beta-L-thymidine and beta-L-2'-deoxycytidine in HepG2 cells and primary human hepatocytes: relevance to chemotherapeutic efficacy against hepatitis B virus. ( Bridges, EG; Bryant, ML; Cretton-Scott, E; Dukhan, D; Faraj, A; Gosselin, G; Hernandez-Santiago, B; Imbach, JL; Pierra, C; Placidi, L; Rodriguez-Orengo, J; Sommadossi, JP, 2002) |
| " Occupational exposure to vinyl chloride causes liver angiosarcomas (ASL) and also increases the risk of several other cancers." | 7.69 | p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers. ( Harris, CC; Hollstein, M; Kusters, I; Lehman, T; Marion, MJ; Martel-Planche, G; Montesano, R; Welsh, J, 1994) |
| "The cumulative incidence of hepatocellular carcinoma development was similar between telbivudine-naive and entecavir-naive patients (p 0." | 5.40 | A comparison of efficacy and safety of 2-year telbivudine and entecavir treatment in patients with chronic hepatitis B: a match-control study. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Tseng, PL; Wang, JH; Yen, YH, 2014) |
| "Albendazole treatment (300 mg/kg per day oral for 20 days) of nude mice inoculated subcutaneously with SKHEP-1, led to profound suppression of tumor growth." | 5.31 | In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. ( Akhter, J; Almajd, R; Bowery, P; Morris, DL; Pourgholami, MH; Woon, L, 2001) |
| " Because previous studies showed that long-term telbivudine treatment improved renal function in chronic hepatitis B virus (HBV) infected patients, we conducted a case-control study to evaluate the clinical outcome of telbivudine preemptive therapy in HBV-related advanced HCC patients treated by combination chemotherapy comprising 5-fluorouracil, mitoxantrone and cisplatin (FMP)." | 5.19 | Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study. ( Chang, ML; Chen, YC; Chien, RN; Hsu, CW; Lin, CL; Yeh, C; Yeh, CT, 2014) |
| "A total of 546 consecutive cirrhotic patients treated with entecavir (n = 359), telbivudine (n = 104), or tenofovir (n = 83) for chronic hepatitis B were enrolled." | 3.85 | Long-term outcomes of hepatitis B virus-related cirrhosis treated with nucleos(t)ide analogs. ( Chen, CH; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Wang, JH, 2017) |
| " To examine changes in phosphorylated Smad3 signalling before and after anti-HBV therapies, we chose 27 patients with chronic hepatitis B who underwent baseline and follow-up biopsies at 52 weeks from the start of nucleoside analogue treatments (Lamivudine 100 mg daily or Telbivudine 600 mg daily)." | 3.80 | Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection. ( Deng, YR; Jin, QL; Lian, ZX; Matsuzaki, K; Moritoki, Y; Murata, M; Niu, JQ; Tsuneyama, K; Yamaguchi, T; Yoshida, K, 2014) |
| "Since the licensing of lamivudine in 1999, the treatment of chronic hepatitis B has been revolutionized by the introduction of oral nucleoside and nucleotide analogues (NAs), which act as inhibitors of the HBV polymerase." | 3.80 | Antiviral therapy of chronic hepatitis B. ( Berg, T; van Bömmel, F, 2014) |
| " Using oxamic acid, an inhibitor of lactic dehydrogenase (LDH) which hinders aerobic glycolysis, we decreased ATP levels in PLC/PRF/5 cells (a line from a hepatocellular carcinoma)." | 3.77 | Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors. ( Di Stefano, G; Fiume, L; Manerba, M; Vettraino, M, 2011) |
| "beta-L-Thymidine (L-dT) and beta-L-2'-deoxycytidine (L-dC) are potent and highly specific inhibitors of hepatitis B virus (HBV) replication both in vivo and in vitro (50% effective concentrations, 0." | 3.71 | Pharmacology of beta-L-thymidine and beta-L-2'-deoxycytidine in HepG2 cells and primary human hepatocytes: relevance to chemotherapeutic efficacy against hepatitis B virus. ( Bridges, EG; Bryant, ML; Cretton-Scott, E; Dukhan, D; Faraj, A; Gosselin, G; Hernandez-Santiago, B; Imbach, JL; Pierra, C; Placidi, L; Rodriguez-Orengo, J; Sommadossi, JP, 2002) |
| " Occupational exposure to vinyl chloride causes liver angiosarcomas (ASL) and also increases the risk of several other cancers." | 3.69 | p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers. ( Harris, CC; Hollstein, M; Kusters, I; Lehman, T; Marion, MJ; Martel-Planche, G; Montesano, R; Welsh, J, 1994) |
| "Carcinogenesis was initiated in female rat liver by a single dose of N-nitrosomorpholine; subsequently phenobarbital (PB) was administered via the diet at a daily dose of 50 mg/kg body weight for up to 49 weeks." | 3.68 | DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion. ( Barthel, G; Bursch, W; Schulte-Hermann, R; Timmermann-Trosiener, I, 1990) |
| " In the present study, however, changes in intracellular cyclic AMP level in several lines of cultured cells (normal 3T3 and SV40 and polyomavirus-transformed 3T3 cells; 3T6, C6 GLIOMA, MOUSE L, and Novikoff rat hepatoma cells) by treatment with papaverine, prostaglandine E1 or isoproterenol did not correlate with the inhibition of the uridine, hypoxanthine or deoxyglucose transport rates by these chemicals." | 3.65 | Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells. ( Plagemann, PG; Sheppard, JR, 1975) |
| "Hepatitis B is a major cause of hepatocellular carcinoma and liver cirrhosis." | 2.52 | Hepatitis B: encouraging the use of interferon. ( Krishnamoorthy, TL; Mutimer, D, 2015) |
| " Long-term use of NUCs with maintained viral suppression results in a decrease in liver-related complications." | 2.52 | Monotherapy for hepatitis B infection: a review of treatment options. ( Demirhan, YE; Gultekin, G; Isal, B; Khodor, H; Ozaras, R; Unal, UK; Yetim, N, 2015) |
| " The incidence of HCC correlated with serum HBV DNA level at entry in a dose-response relationship." | 2.44 | Active antiviral therapy for chronic hepatitis B and hepatocellular carcinoma. ( Hann, HW, 2008) |
| "Mortality and complications including hepatocellular carcinoma are associated primarily with cirrhosis and age, but not with HBeAg status or viral load probably because modern therapies considerably reduce viral replication in almost all patients." | 1.43 | Long-term follow-up of HBsAg-positive patients in Germany. ( Amani, A; Niederau, C; Thiel, A, 2016) |
| "TK1 was responsible for anticancer activity of dT-QX while levels of TYMP counteracted such an activity." | 1.42 | Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways. ( Liu, H; Wei, Q; Zhang, D; Zhang, Z; Zhou, H; Zhou, Q, 2015) |
| "The cumulative incidence of hepatocellular carcinoma development was similar between telbivudine-naive and entecavir-naive patients (p 0." | 1.40 | A comparison of efficacy and safety of 2-year telbivudine and entecavir treatment in patients with chronic hepatitis B: a match-control study. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Tseng, PL; Wang, JH; Yen, YH, 2014) |
| "Magnolol was not cytotoxic at these concentrations and this indicates that it may have an inhibitory effect on cell proliferation in the subcultured cancer cell lines." | 1.31 | Magnolol suppresses proliferation of cultured human colon and liver cancer cells by inhibiting DNA synthesis and activating apoptosis. ( Chang, HC; Lee, WS; Lin, CH; Lin, SY; Liu, JD; Yeh, SD, 2002) |
| "Albendazole treatment (300 mg/kg per day oral for 20 days) of nude mice inoculated subcutaneously with SKHEP-1, led to profound suppression of tumor growth." | 1.31 | In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. ( Akhter, J; Almajd, R; Bowery, P; Morris, DL; Pourgholami, MH; Woon, L, 2001) |
| "The results suggest that B16 melanoma releases qHSC-activating factors, which induce the appearance of metastasis-infiltrating myofibroblasts by a paracrine mechanism." | 1.30 | Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis. ( Bidaurrazaga, J; Gressner, AM; Olaso, E; Rosenbaum, J; Santisteban, A; Vidal-Vanaclocha, F, 1997) |
| "The number of colonies of hepatic metastasis correlated well with the area under the curve of the distributed amount of the tumor cells in the liver, regardless of the injection route; the correlation line was identical for each injection route." | 1.30 | Importance of hepatic first-pass removal in metastasis of colon carcinoma cells. ( Irimura, T; Izumi, Y; Kato, Y; Mizuno, N; Sugiyama, Y, 1998) |
| "Hepatic granulomas were formed in the osteopetrotic mice by glucan injection without a supply of blood monocytes." | 1.29 | The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor. ( Naito, M; Shultz, LD; Takahashi, K; Umeda, S, 1994) |
| "In the present series of hepatocellular carcinoma patients, the 3-year clinical outcome was significantly affected by cell proliferation and ECM-associated antigens." | 1.29 | Biological markers in hepatocellular carcinoma: potential clinical implications. ( Costa, A; D'Errico, A; Faranda, A; Gennari, L; Grigioni, W; Regalia, E; Silvestrini, R, 1993) |
| "Crisnatol was metabolized extensively by both systems." | 1.28 | Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites. ( Chang, SY; Huber, BE; Patel, DK; Shockcor, JP; Sigel, CW, 1991) |
| "Nafenopin treatment resulted in a proliferation of peroxisomes within the cultured cells." | 1.27 | Use of primary cultures of adult rat hepatocytes to investigate mechanisms of action of nafenopin, a hepatocarcinogenic peroxisome proliferator. ( Bentley, P; Bieri, F; Stäubli, W; Waechter, F, 1984) |
| " Furthermore, chronic administration of 0." | 1.27 | Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats. ( Denda, A; Emi, Y; Konishi, Y; Mikami, S; Nakae, D; Ohnishi, T; Takahashi, S; Yokose, Y, 1984) |
| " Therefore, we have begun to quantify the dose-response relationships for N-nitrosodiethylamine (NDEA)-induced hepatocarcinogenesis by characterizing the major promutagenic DNA adduct, O4-ethyldeoxythymidine (O4-etdT); hepatocyte proliferation; and hepatocyte initiation in rats continually exposed to drinking-water containing NDEA." | 1.27 | Molecular dosimetry of DNA alkylation during chronic exposure to carcinogens. ( Boucheron, JA; Deal, FH; Richardson, FC; Swenberg, JA; Tyeryar, LA, 1987) |
| "The ability to form spontaneous metastasis (SM) in the lungs and in other organs appears among cell variants isolated at days 10 to 21 after inoculation." | 1.27 | Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity. ( Deichman, GI; Vendrov, EL, 1986) |
| "Two human primary liver cancer cell-lines, PLC/PRF/5 and Hep 3B, grown both in vitro and as xenografts in nude mice were used to evaluate the chemotherapeutic potential of a new quinazoline antifolate CB3717." | 1.27 | Inhibition of the growth of human hepatocellular carcinoma in vitro and in athymic mice by a quinazoline inhibitor of thymidylate synthase, CB3717. ( Bassendine, MF; Curtin, NJ; Harris, AL; James, OF, 1986) |
| "Reuber (H35) hepatoma cells were grown in medium containing 10(-5)M bromodeoxyuridine (BrdU), which was incorporated into their DNA." | 1.26 | The diverse effects of 5'-bromodeoxyuridine on enzyme activities in cultured H35 hepatoma cells. ( Becker, JE; Gurr, JA; Potter, VR, 1977) |
| "On the contrary, in hepatoma 48 possessing the same rate of growth the cell production was much more intensive, the rate of cell death being very high." | 1.26 | [Kinetics of cell proliferation and growth of transplanted hepatoma in mice]. ( Gel'shteĭn, VI; Klempner, LB, 1976) |
| "Novikoff rat hepatoma cells were propagated in suspension culture in the presence of 1 micron methotrexate and various concentrations of hypoxanthine (or adenosine plus guanosine) and thymidine and with or without the inhibitor of nucleoside and purine transport, Persantin (dipyridamole)." | 1.26 | Growth rate of cultured Novikoff rat hepatoma cells as a function of the rate of thymidine and hypoxanthine transport. ( Marz, R; Plagemann, PG; Wohlhueter, RM, 1977) |
| "The rat hepatoma cell H4-12 which synthesizes and secretes albumin was synchronized by growth in isoleucine-deficient medium followed by a second block with excess thymidine." | 1.26 | Synthesis and secretion of albumin by a synchronized rat hepatoma cell line. ( Chen, LL; Redman, CM, 1977) |
| "In the hepatoma cells, the enzyme activities were also compared to the cellular content and synthesis of RNA and DNA." | 1.26 | Nucleotidase activity in regenerating liver and in clonal strains of hepatoma and pituitary cells in culture. ( Gautvik, KM; Tjernshaugen, H, 1976) |
| "Studies on RNA synthesis in Novikoff hepatoma ascites cells in vitro showed there was a decreased uptake of 32Pi into high molecular weight nuclear RNA in the presence of bleomycin A2." | 1.25 | Biochemical effects of bleomycin A2 on Novikoff hepatoma ascites cells. ( Bannon, M; Busch, H; Crooke, ST; Sitz, TO, 1975) |
| "Populations of Novikoff rat hepatoma cells (subline N1S1-67) were monitored for the rates of transport of various substrates and for their incorporation into acid-insoluble material as a function of the age of cultures of randomly growing cells in suspension as well as during traverse of the cells through the cell cycle." | 1.25 | Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells. ( Erbe, J; Plagemenn, PG; Richey, DP; Zylka, JM, 1975) |
| "The factor was not present in serum of hepatoma-bearing animals at a time when the weight of the hepatomas was equal to or greater than liver weight." | 1.25 | Effect of a normal serum protein absent from hepatoma-bearing animals on cell cultures. ( Coetzee, ML; Dolan, ML; Ove, P; Spangler, M, 1975) |
| "The mitotic activity of the hepatoma was found to increase by 3 to 4 times (12-15 hours after inoculation)." | 1.25 | [Regenerative growth of asvitic hepatoma 22A]. ( Beliaeva, ID; Ivleva, TS, 1975) |
| "DNA synthesis in a transplanted hepatoma induced by 3'-methyl-4-dimethylaminoazobenzene was significantly reduced (P less than 0." | 1.25 | Zinc intake, neoplastic DNA synthesis, and chemical carcinogenesis in rats and mice. ( Dreosti, IE; Duncan, JR, 1975) |
| "The clone Fu 5 a of the Reuber Hepatoma cell line was incubated with corticosterone for 48 hours." | 1.25 | [Corticosterone, a synchronizing factor for liver cells]. ( Desser-Wiest, L, 1975) |
| "Primary tumors and their metastases in regional lymph nodes show certain differences relative both to the rate of the process and intensity of the DNA synthesis, and relative number of cells with incorporated labelled thymidine." | 1.25 | [A kinetic analysis of the growth of transplanted tumors and their metastasis]. ( D'iachkovskaia, RF; Emanuel', NM; Kiseleva, EG; Konovalova, NP; Volkova, IM, 1975) |
| "In H-35 hepatomas growing subcutaneously, synthesis of DNA, as shown by incorporation of tritiated thymidine, was depressed 18 hours after a two-thirds hepatectomy in the host." | 1.25 | Effects of partial hepatectomy in rats on two transplantable hepatomas. Changes in weight and in synthesis of DNA and ferritin. ( Lee, JC, 1971) |
| "Growth of cultured rat hepatoma cells in the presence of 5-bromodeoxyuridine results in a rapid inhibition of the synthesis of adrenal steroid-inducible tyrosine aminotransferase (EC 2." | 1.25 | Differential effect of 5-bromodeoxyuridine on the concentrations of specific enzymes in hepatoma cells in culture. ( Stellwagen, RH; Tomkins, GM, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 256 (79.26) | 18.7374 |
| 1990's | 30 (9.29) | 18.2507 |
| 2000's | 19 (5.88) | 29.6817 |
| 2010's | 18 (5.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matthes, E | 1 |
| Funk, A | 1 |
| Krahn, I | 1 |
| Gaertner, K | 1 |
| von Janta-Lipinski, M | 1 |
| Lin, L | 1 |
| Will, H | 1 |
| Sirma, H | 1 |
| He, L | 1 |
| Liu, X | 1 |
| Zhao, Y | 1 |
| Zhang, S | 2 |
| Jiang, Y | 1 |
| Wang, X | 1 |
| Yang, Z | 1 |
| Tsai, MC | 2 |
| Chen, CH | 2 |
| Hung, CH | 2 |
| Lee, CM | 2 |
| Chiu, KW | 1 |
| Wang, JH | 2 |
| Lu, SN | 2 |
| Tseng, PL | 1 |
| Chang, KC | 1 |
| Yen, YH | 1 |
| Hu, TH | 2 |
| Singal, AK | 1 |
| Salameh, H | 1 |
| Kuo, YF | 1 |
| Fontana, RJ | 1 |
| Lao, XM | 1 |
| Xia, HH | 1 |
| Lin, XJ | 1 |
| Li, SP | 1 |
| Park, YH | 1 |
| Kim, BK | 1 |
| Kim, JK | 1 |
| Kim, HC | 1 |
| Kim, DY | 1 |
| Park, JY | 1 |
| Han, KH | 1 |
| Kim, SU | 1 |
| Shin, SH | 1 |
| Hahn, KY | 1 |
| Ahn, SH | 1 |
| Deng, YR | 1 |
| Yoshida, K | 2 |
| Jin, QL | 1 |
| Murata, M | 2 |
| Yamaguchi, T | 1 |
| Tsuneyama, K | 1 |
| Moritoki, Y | 1 |
| Niu, JQ | 1 |
| Matsuzaki, K | 2 |
| Lian, ZX | 1 |
| Calvaruso, V | 1 |
| Craxì, A | 1 |
| van Bömmel, F | 1 |
| Berg, T | 1 |
| Lin, CL | 1 |
| Chien, RN | 2 |
| Yeh, C | 1 |
| Hsu, CW | 1 |
| Chang, ML | 1 |
| Chen, YC | 1 |
| Yeh, CT | 1 |
| Coffin, CS | 1 |
| Rezaeeaval, M | 1 |
| Pang, JX | 1 |
| Alcantara, L | 1 |
| Klein, P | 1 |
| Burak, KW | 1 |
| Myers, RP | 1 |
| Wei, Q | 1 |
| Liu, H | 1 |
| Zhou, H | 1 |
| Zhang, D | 1 |
| Zhang, Z | 1 |
| Zhou, Q | 1 |
| Krishnamoorthy, TL | 1 |
| Mutimer, D | 1 |
| Ozaras, R | 1 |
| Khodor, H | 1 |
| Yetim, N | 1 |
| Unal, UK | 1 |
| Demirhan, YE | 1 |
| Gultekin, G | 1 |
| Isal, B | 1 |
| Niederau, C | 1 |
| Amani, A | 1 |
| Thiel, A | 1 |
| Gao, S | 1 |
| Zhao, M | 1 |
| Liu, Y | 1 |
| Bu, Y | 1 |
| Jiang, Q | 1 |
| Zhao, Q | 1 |
| Ye, L | 1 |
| Zhang, X | 1 |
| Liaw, YF | 1 |
| MacKenna, DA | 1 |
| Montag, A | 1 |
| Boyer, SH | 1 |
| Linemeyer, DL | 1 |
| Erion, MD | 1 |
| Fiume, L | 1 |
| Vettraino, M | 1 |
| Manerba, M | 1 |
| Di Stefano, G | 1 |
| Cho, YK | 1 |
| Song, BC | 1 |
| Enosawa, S | 1 |
| Miyashita, T | 1 |
| Endo, M | 1 |
| Suzuki, S | 1 |
| Amemiya, H | 1 |
| Matsumura, T | 1 |
| Ng, TB | 1 |
| Lam, SK | 1 |
| Fong, WP | 1 |
| BEHKI, RM | 1 |
| SCHNEIDER, WC | 1 |
| DE RECONDO, AM | 2 |
| FRAYSSINET, C | 3 |
| DE RECONDO, JJ | 1 |
| OETTGEN, HF | 1 |
| CLIFFORD, P | 1 |
| CANDLER, P | 1 |
| NIXON, JC | 1 |
| ZBARSKY, SH | 1 |
| MANDEL, P | 2 |
| WINTZERITH, M | 2 |
| BORKOWSKA, I | 1 |
| MANDEL, L | 1 |
| POST, J | 3 |
| HOFFMAN, J | 3 |
| ROTH, JS | 2 |
| OEHLERT, W | 1 |
| MAGNUSSON, B | 1 |
| FOX, BW | 1 |
| PRUSOFF, WH | 1 |
| IVES, DH | 3 |
| BUKOVSKY, J | 1 |
| MORSE, PA | 3 |
| POTTER, VR | 10 |
| GENTRY, GA | 2 |
| GEBERT, R | 1 |
| Gebhardt, R | 1 |
| Chan, KK | 1 |
| Chan, JY | 1 |
| Chung, KK | 1 |
| Fung, KP | 1 |
| Stervbo, U | 1 |
| Vang, O | 1 |
| Bonnesen, C | 1 |
| Sekimoto, G | 1 |
| Uemura, Y | 1 |
| Sakaida, N | 1 |
| Kaibori, M | 1 |
| Kamiyama, Y | 1 |
| Nishizawa, M | 1 |
| Fujisawa, J | 1 |
| Okazaki, K | 1 |
| Seki, T | 1 |
| Hann, HW | 1 |
| Metcalf, D | 1 |
| Ishidate, M | 1 |
| Brumby, M | 1 |
| Zhao, YL | 1 |
| Tatematsu, M | 1 |
| Nagamine, Y | 1 |
| Farber, E | 1 |
| Konishi, Y | 2 |
| Takahashi, S | 2 |
| Ohnishi, T | 2 |
| Denda, A | 2 |
| Mikami, S | 2 |
| Emi, Y | 2 |
| Nakae, D | 2 |
| Yokose, Y | 1 |
| Bieri, F | 1 |
| Bentley, P | 1 |
| Waechter, F | 1 |
| Stäubli, W | 1 |
| Aoki, K | 1 |
| Matsudaira, H | 2 |
| Grosfeld, JL | 2 |
| Weber, TR | 1 |
| Baehner, RL | 1 |
| Heiman, AS | 1 |
| Tonner, LE | 1 |
| Rashed, HM | 1 |
| Sun, H | 1 |
| Patel, TB | 1 |
| Su, J | 1 |
| Zhen, YC | 1 |
| Qi, CQ | 1 |
| Hu, JL | 1 |
| Prat, F | 1 |
| Centarti, M | 1 |
| Sibille, A | 1 |
| Abou el Fadil, FA | 1 |
| Henry, L | 1 |
| Chapelon, JY | 1 |
| Cathignol, D | 1 |
| Engum, SA | 1 |
| Sidner, RA | 1 |
| Miller, GA | 1 |
| Park, KG | 1 |
| Heys, SD | 1 |
| McNurlan, MA | 1 |
| Garlick, PJ | 1 |
| Eremin, O | 1 |
| Guo, P | 1 |
| Scholz, E | 1 |
| Turek, J | 1 |
| Nodgreen, R | 1 |
| Maloney, B | 1 |
| Takahashi, K | 1 |
| Naito, M | 1 |
| Umeda, S | 1 |
| Shultz, LD | 1 |
| Hollstein, M | 1 |
| Marion, MJ | 1 |
| Lehman, T | 1 |
| Welsh, J | 1 |
| Harris, CC | 1 |
| Martel-Planche, G | 1 |
| Kusters, I | 1 |
| Montesano, R | 1 |
| Silvestrini, R | 2 |
| Costa, A | 2 |
| D'Errico, A | 1 |
| Faranda, A | 1 |
| Regalia, E | 2 |
| Grigioni, W | 1 |
| Gennari, L | 1 |
| Hung, WC | 1 |
| Chuang, LY | 1 |
| Tsai, JH | 1 |
| Chang, CC | 1 |
| Velázquez, OC | 1 |
| Jabbar, A | 1 |
| DeMatteo, RP | 1 |
| Rombeau, JL | 1 |
| Olaso, E | 1 |
| Santisteban, A | 1 |
| Bidaurrazaga, J | 1 |
| Gressner, AM | 1 |
| Rosenbaum, J | 1 |
| Vidal-Vanaclocha, F | 1 |
| Mizuno, N | 1 |
| Kato, Y | 1 |
| Izumi, Y | 1 |
| Irimura, T | 1 |
| Sugiyama, Y | 1 |
| Gagandeep, S | 1 |
| Novikoff, PM | 1 |
| Ott, M | 1 |
| Gupta, S | 1 |
| de Jong, KP | 1 |
| Brinker, M | 1 |
| van Veen, M | 1 |
| Daemen, T | 2 |
| Scherphof, GL | 2 |
| Slooff, MJ | 1 |
| Schmidt, CM | 1 |
| McKillop, IH | 1 |
| Cahill, PA | 1 |
| Sitzmann, JV | 1 |
| Zhang, M | 2 |
| Gong, Y | 2 |
| Assy, N | 1 |
| Minuk, GY | 2 |
| Pourgholami, MH | 2 |
| Akhter, J | 2 |
| Lu, Y | 1 |
| Morris, DL | 2 |
| Woon, L | 1 |
| Almajd, R | 1 |
| Bowery, P | 1 |
| Marino, M | 1 |
| Distefano, E | 1 |
| Caporali, S | 1 |
| Ceracchi, G | 1 |
| Pallottini, V | 1 |
| Trentalance, A | 1 |
| Iciek, MB | 1 |
| Rokita, HB | 1 |
| Wlodek, LB | 1 |
| Lin, SY | 1 |
| Liu, JD | 1 |
| Chang, HC | 1 |
| Yeh, SD | 1 |
| Lin, CH | 1 |
| Lee, WS | 1 |
| Deng, S | 1 |
| Wang, G | 1 |
| Burczynski, F | 1 |
| Li, Y | 1 |
| Xing, G | 1 |
| Wang, Q | 1 |
| Li, M | 1 |
| Wei, H | 1 |
| Fan, G | 1 |
| Chen, J | 1 |
| Yang, X | 1 |
| Wu, C | 1 |
| Chen, H | 1 |
| He, F | 1 |
| Hernandez-Santiago, B | 1 |
| Placidi, L | 1 |
| Cretton-Scott, E | 1 |
| Faraj, A | 1 |
| Bridges, EG | 1 |
| Bryant, ML | 1 |
| Rodriguez-Orengo, J | 1 |
| Imbach, JL | 1 |
| Gosselin, G | 1 |
| Pierra, C | 1 |
| Dukhan, D | 1 |
| Sommadossi, JP | 1 |
| Bushnell, DE | 3 |
| O'Brien, JC | 1 |
| Stellwagen, RH | 2 |
| Gurr, JA | 1 |
| Becker, JE | 2 |
| Keefer, RC | 1 |
| MacNamara, DJ | 1 |
| Schumm, DE | 1 |
| Billmire, DF | 1 |
| Webb, TE | 1 |
| Churchill, WH | 2 |
| Piessens, WF | 2 |
| Sulis, CA | 1 |
| David, JR | 1 |
| Crooke, ST | 1 |
| Sitz, TO | 1 |
| Bannon, M | 1 |
| Busch, H | 1 |
| Looney, WB | 8 |
| Mayo, AA | 3 |
| Kovacs, CJ | 1 |
| Hopkins, HA | 2 |
| Simon, R | 1 |
| Morris, HP | 26 |
| Coetzee, ML | 5 |
| Sartiano, GP | 1 |
| Klein, K | 1 |
| Ove, P | 7 |
| Plagemenn, PG | 1 |
| Richey, DP | 2 |
| Zylka, JM | 2 |
| Erbe, J | 5 |
| Dolan, ML | 2 |
| Spangler, M | 2 |
| Sheppard, JR | 2 |
| Plagemann, PG | 16 |
| Hilliard, JK | 1 |
| Sneider, TW | 5 |
| McCann, PP | 1 |
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| Schuber, F | 1 |
| Beliaeva, ID | 1 |
| Ivleva, TS | 1 |
| Duncan, JR | 1 |
| Dreosti, IE | 1 |
| Deschamps, Y | 1 |
| Verly, WG | 3 |
| Amalric, F | 1 |
| Zalta, JP | 1 |
| Desser-Wiest, L | 1 |
| Longo, FW | 1 |
| Tomashefsky, P | 1 |
| Rivin, BD | 1 |
| Longo, WE | 1 |
| Lattimer, JK | 1 |
| Willhite, M | 1 |
| Tannenbaum, M | 1 |
| Baliga, BS | 1 |
| Borek, E | 1 |
| Emanuel', NM | 1 |
| Kiseleva, EG | 1 |
| D'iachkovskaia, RF | 1 |
| Konovalova, NP | 1 |
| Volkova, IM | 1 |
| Tjernshaugen, H | 1 |
| Gautvik, KM | 1 |
| Parkhurst, JR | 1 |
| Danenberg, PV | 1 |
| Heidelberger, C | 3 |
| Behrens, M | 1 |
| Wilkinson, DS | 1 |
| Crumley, J | 1 |
| Jackson, RC | 1 |
| Weber, G | 7 |
| Wakefield, JA | 1 |
| Wohlhueter, RM | 4 |
| Marz, R | 4 |
| Graff, JC | 1 |
| Klempner, LB | 2 |
| Gel'shteĭn, VI | 3 |
| Hial, V | 1 |
| De Mello, MC | 1 |
| Horakova, Z | 1 |
| Beaven, MA | 1 |
| Chen, LL | 1 |
| Redman, CM | 1 |
| Kuo, CY | 1 |
| Yoo, TJ | 1 |
| Barra, R | 1 |
| Hicks, H | 1 |
| Koch, MR | 1 |
| Lea, MA | 10 |
| Ogawa, K | 1 |
| Enomoto, K | 1 |
| Yoshida, Y | 1 |
| Onoé, T | 1 |
| Armuth, V | 1 |
| Berenblum, I | 1 |
| Uryvaeva, IV | 1 |
| Faktor, VM | 1 |
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| Gelehrter, TD | 2 |
| Kojima, S | 1 |
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| Shiki, Y | 1 |
| Kubodera, A | 1 |
| Anghileri, LJ | 1 |
| Heidbreder, M | 1 |
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| Ohhira, M | 1 |
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| Fujii, S | 2 |
| Ozawa, K | 1 |
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| Patel, DK | 1 |
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| Huber, BE | 2 |
| Galun, E | 1 |
| Shouval, D | 1 |
| Adler, R | 1 |
| Shahaar, M | 1 |
| Wilchek, M | 1 |
| Hurwitz, E | 1 |
| Sela, M | 1 |
| Fukutomi, Y | 1 |
| Omori, M | 1 |
| Muto, Y | 1 |
| Ninomiya, M | 1 |
| Okuno, M | 1 |
| Moriwaki, H | 1 |
| Franchi, F | 1 |
| Seminara, P | 1 |
| Giannarelli, D | 1 |
| Konovalova, N | 1 |
| Duronio, V | 1 |
| Jacobs, S | 1 |
| Calabresi, P | 1 |
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| Schulte-Hermann, R | 1 |
| Timmermann-Trosiener, I | 1 |
| Barthel, G | 1 |
| Bursch, W | 1 |
| Motoo, Y | 1 |
| Kobayashi, K | 1 |
| Hattori, N | 1 |
| Swenberg, JA | 1 |
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| Spanjer, HH | 1 |
| Roerdink, FH | 1 |
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| Rogers, AE | 6 |
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| Ono, T | 5 |
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| Malenkov, AG | 3 |
| Modianova, EA | 1 |
| Rabes, HM | 2 |
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| Satake, S | 1 |
| Yoshida, T | 1 |
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| Sripati, CE | 1 |
| Khouvine, Y | 1 |
| Sasovetz, D | 2 |
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| Oppenheim, JJ | 2 |
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| Lin, JY | 1 |
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| Miyamoto, M | 2 |
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| Janners, MY | 2 |
| Mellon, JG | 2 |
| Allen, P | 2 |
| Salak, D | 2 |
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| Ferdinandus, JA | 3 |
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| Sternberg, SS | 2 |
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| Queener, SF | 2 |
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| Sartorelli, AC | 3 |
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| Moore, EC | 3 |
| Murphy, P | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Chemoembolization With or Without Antiviral Therapy for Unresectable HBV-related Hepatocellular Carcinoma With Low HBV DNA Replication: Effectiveness and Safety. A Prospective and Randomized Clinical Trial[NCT01894269] | Phase 4 | 200 participants (Anticipated) | Interventional | 2013-07-31 | Recruiting | ||
| A Prospective, Observational, Single-center Post-marketing Surveillance Study of Telbivudine in Chronic Hepatitis B Adults With HBeAg Positive/Negative.[NCT00970216] | 160 participants (Actual) | Observational | 2009-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT00970216)
Timeframe: 48 weeks
| Intervention | participants (Number) |
|---|---|
| Chronic Hepatitis B | 79 |
13 reviews available for thymidine and Liver Neoplasms
| Article | Year |
|---|---|
Efficacy of Nucleot(s)ide Analogs Therapy in Patients with Unresectable HBV-Related Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Guanine; Hepatitis B v | 2017 |
Meta-analysis: the impact of oral anti-viral agents on the incidence of hepatocellular carcinoma in chronic hepatitis B.
Topics: Adenine; Administration, Oral; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; He | 2013 |
Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible?
Topics: Adenine; Administration, Oral; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Guanine; Hepat | 2014 |
Hepatitis B: encouraging the use of interferon.
Topics: Adjuvants, Immunologic; Antiviral Agents; Carcinoma, Hepatocellular; Contraindications; Drug Adminis | 2015 |
Monotherapy for hepatitis B infection: a review of treatment options.
Topics: Adenine; Animals; Antiviral Agents; Carcinoma, Hepatocellular; Guanine; Hepatitis B, Chronic; Humans | 2015 |
Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success.
Topics: Adenine; Adenine Nucleotides; Alanine Transaminase; Carcinoma, Hepatocellular; DNA, Viral; Drug Admi | 2008 |
Active antiviral therapy for chronic hepatitis B and hepatocellular carcinoma.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Hepatitis B, Chronic; Humans; Interferons; Lamivudine; | 2008 |
Solid tumor models for the assessment of different treatment modalities: II: rapid, intermediate, and slow growing transplantable rat hepatomas.
Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cell Division; Cyclic AMP; Cyclic GMP; Disea | 1976 |
Metabolism of thymine in tumor tissue: the origins of beta-aminoisobutyric acid.
Topics: Age Factors; Aminoisobutyric Acids; Animals; Carcinoma, Hepatocellular; Cell Line; DNA; Liver Neopla | 1975 |
Cell kinetics in the study of hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Cell Cycle; Cytological Techniques; Humans; Kinetics; Liver; Liver Neopla | 1992 |
The molecular correlation concept of neoplasia.
Topics: Amino Acids; Animals; Biochemical Phenomena; Biochemistry; Carbohydrate Metabolism; Carbon Isotopes; | 1966 |
[Deoxythimidine kinase].
Topics: Adrenocorticotropic Hormone; Animals; Carcinoma, Ehrlich Tumor; Cell Division; Chromatography, DEAE- | 1971 |
Growth kinetics of solid tumors.
Topics: Animals; Antineoplastic Agents; Autoradiography; Carcinogens; Carcinoma, Hepatocellular; Cell Count; | 1972 |
1 trial available for thymidine and Liver Neoplasms
| Article | Year |
|---|---|
Significant renoprotective effect of telbivudine during preemptive antiviral therapy in advanced liver cancer patients receiving cisplatin-based chemotherapy: a case-control study.
Topics: Acute Kidney Injury; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoc | 2014 |
309 other studies available for thymidine and Liver Neoplasms
| Article | Year |
|---|---|
Strong and selective inhibitors of hepatitis B virus replication among novel N4-hydroxy- and 5-methyl-beta-L-deoxycytidine analogues.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Deoxycytidine; Dose-Response Relation | 2007 |
A comparison of efficacy and safety of 2-year telbivudine and entecavir treatment in patients with chronic hepatitis B: a match-control study.
Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Drug Res | 2014 |
Antiviral therapy in patients with hepatitis B virus-related hepatocellular carcinoma: is it ready for universal application?
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Hepatectomy; Hepatitis B, Chronic; Humans; Liver Neopla | 2013 |
Long-term outcomes of chronic hepatitis B virus infection in the era of antiviral therapy in Korea.
Topics: Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Female; Follow | 2014 |
Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection.
Topics: Adult; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; DNA, Viral; Female; Hepatit | 2014 |
Antiviral therapy of chronic hepatitis B.
Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Gene Products, pol; Gu | 2014 |
The incidence of hepatocellular carcinoma is reduced in patients with chronic hepatitis B on long-term nucleos(t)ide analogue therapy.
Topics: Adenine; Adult; Antiviral Agents; Canada; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e | 2014 |
Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytosol; Disease Models, Animal; Gene Expression; | 2015 |
Long-term follow-up of HBsAg-positive patients in Germany.
Topics: Adenine; Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Drug Therapy, | 2016 |
Long-term outcomes of hepatitis B virus-related cirrhosis treated with nucleos(t)ide analogs.
Topics: Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B, Chronic; Hum | 2017 |
Anti-HBV drugs suppress the growth of HBV-related hepatoma cells via down-regulation of hepatitis B virus X protein.
Topics: Animals; Antiviral Agents; Carcinoma, Hepatocellular; Cell Proliferation; DNA Replication; DNA, Vira | 2017 |
Delivery of high levels of anti-proliferative nucleoside triphosphates to CYP3A-expressing cells as a potential treatment for hepatocellular carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Pro | 2009 |
Inhibition of lactic dehydrogenase as a way to increase the anti-proliferative effect of multi-targeted kinase inhibitors.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Benzenesulfonates; Carcinoma, Hepatocellular; Cell Li | 2011 |
[New insight for HBV DNA and HBsAg quantitation during antiviral therapy in patients with chronic hepatitis B].
Topics: Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Hepatitis B Surface Antigens; Hepatitis B v | 2011 |
Off-line bioartificial liver: a novel concept of treatment and its potency of liver regeneration.
Topics: Animals; Bioreactors; Carcinoma, Hepatocellular; DNA; Equipment Design; Hepatocytes; Humans; Liver N | 2002 |
A homodimeric sporamin-type trypsin inhibitor with antiproliferative, HIV reverse transcriptase-inhibitory and antifungal activities from wampee (Clausena lansium) seeds.
Topics: Amino Acid Sequence; Animals; Antifungal Agents; Antineoplastic Agents, Phytogenic; Dimerization; Fu | 2003 |
Incorporation of tritiated thymidine into deoxyribonucleic acid by isolated nuclei.
Topics: Carcinoma, Hepatocellular; Cell Nucleus; DNA; Ligases; Liver; Liver Neoplasms; Thymidine | 1963 |
[Incorporation of tritiated thymidine into various types of experimental hepatoma in the rat].
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Liver Neoplasms, Experimental; Neoplasms; Neopl | 1963 |
CONTINUOUS INTRA-ARTERIAL OR INTRAVENOUS INFUSION OF 5-FLUORO-2-DEOXYURIDINE: THERAPEUTIC AND TOXIC EFFECTS.
Topics: Adenocarcinoma; Carcinoma; Carcinoma, Squamous Cell; Carotid Arteries; Chemotherapy, Cancer, Regiona | 1963 |
THE EFFECT OF SOME TRANSPLANTABLE TUMORS ON THE NUCLEIC ACID METABOLISM OF THE HOST TISSUES.
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma 256, Walker; Carcinoma, Ehrlich Tumor; Carcinoma, Hepat | 1963 |
[ON THE EXISTENCE OF RAPIDLY LABELED DESOXYRIBONUCLEIC FRACTION IN ANIMAL CELLS].
Topics: Adenine; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; DNA; Liver; Liver Neoplasms; Neoplasm | 1964 |
THE REPLICATION TIME AND PATTERN OF CARCINOGEN--INDUCED HEPATOMA CELLS.
Topics: Autoradiography; Carcinogens; Carcinoma, Hepatocellular; Cell Division; DNA; DNA, Neoplasm; Liver Ne | 1964 |
INCREASED STABILITY OF TEMPLATES FOR SOME ENZYMES OF DNA SYNTHESIS IN TUMORS: DEOXYCYTIDYLATE DEAMINASE, THYMIDINE AND THYMIDYLATE KINASE.
Topics: Animals; Carcinoma, Hepatocellular; Chick Embryo; Dactinomycin; DCMP Deaminase; DNA; DNA, Neoplasm; | 1964 |
[DNA SYNTHESIS IN VITRO: ACTIVATION OF DNA NECESSARY FOR REACTION BY SUPERNATANTS OF HOMOGENATES OF LIVERS IN COMPENSATORY HYPERTROPHY AND OF HEPATOMAS: ENZYMATIC MECHANISMS INVOLVED].
Topics: Carcinoma, Hepatocellular; Deoxyribonucleases; DNA; Hepatomegaly; Hypertrophy; In Vitro Techniques; | 1964 |
[AUTORADIOGRAPHIC STUDIES ON THE INCORPORATION OF 5-IODO-2-DESOXYURIDINE (IUDR) INTO THE DNA OF CELLS OF YOSHIDA HEPATOMA AH 130].
Topics: Autoradiography; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Idoxuridine; Liver Neoplasms; Neopla | 1965 |
THE COMPARATIVE UPTAKE OF I-125-LABELED 5-IODO-2'-DEOXYURIDINE AND THYMIDINE-H3 INTO TISSUES OF MICE BEARING HEPATOMA-129.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Histocytochemistry; Idoxuridine; Inte | 1965 |
EVIDENCE FOR THYMIDINE DIPHOSPHATE AS THE PRECURSOR OF THYMIDINE TRIPHOSPHATE IN TUMOR. TRANSFER OF THE TERMINAL PHOSPHATE OF ADENOSINE TRIPHOSPHATE TO THYMIDYLATE.
Topics: Adenosine Triphosphate; Carcinoma, Hepatocellular; Chromatography; Liver Neoplasms; Nucleotides; Pho | 1965 |
SOME FACTORS AFFECTING THE PHOSPHORYLATION OF THYMIDINE BY TRANSPLANTABLE RAT HEPATOMAS.
Topics: Carcinoma, Hepatocellular; Chromatography; Edetic Acid; Histocytochemistry; Liver Neoplasms; Magnesi | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liv | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. II. THYMIDINE UPTAKE IN SUSPENSION CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; DNA; DNA, Neoplasm; Liver Neopl | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. 3. RELATIONSHIP OF THYMIDINE TO THE METABOLISM OF OTHER PYRIMIDINE NUCLEOSIDES IN SUSPENSION CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Liver Neoplasms; Liver Neoplasms, Experiment | 1965 |
Antioxidative, antiproliferative and biochemical effects in HepG2 cells of a homeopathic remedy and its constituent plant tinctures tested separately or in combination.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Cell Line, Tumor; Cell Survival; Culture Media; Glu | 2003 |
Inhibition of cell proliferation in human breast tumor cells by antisense oligonucleotides against facilitative glucose transporter 5.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Proliferation; Female; Fructose | 2004 |
Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells.
Topics: Annexin A5; Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Nucleus | 2006 |
Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.
Topics: alpha-Fetoproteins; Biopsy; Carcinoma, Hepatocellular; Disease Progression; DNA Replication; Hepatit | 2007 |
Proliferation and behavior of phagocytic cells in mouse lymphoma tissue.
Topics: Animals; Autoradiography; Cell Division; Female; Leukemia, Lymphoid; Liver; Liver Neoplasms; Lymph N | 1967 |
[Properties of cancer-inhibition factor and its relation to cyclic AMP].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cyclic AMP; Female; Liver Neoplasms; Male; | 1984 |
Redifferentiation as a basis for remodeling of carcinogen-induced hepatocyte nodules to normal appearing liver.
Topics: 2-Acetylaminofluorene; Acyltransferases; Animals; Cell Differentiation; DNA Replication; Liver; Live | 1983 |
Possible role of poly(ADP-ribose) polymerase on the early stage of liver carcinogenesis by diethylnitrosamine in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Benzamides; Diethylnitrosamine; Dimethyl | 1983 |
Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats.
Topics: Animals; Benzamides; Diethylnitrosamine; DNA Repair; gamma-Glutamyltransferase; Liver; Liver Neoplas | 1984 |
Use of primary cultures of adult rat hepatocytes to investigate mechanisms of action of nafenopin, a hepatocarcinogenic peroxisome proliferator.
Topics: Animals; Cells, Cultured; DNA; DNA Repair; gamma-Glutamyltransferase; Hydroxyurea; Liver; Liver Neop | 1984 |
Factors influencing methylazoxymethanol acetate initiation of liver tumors in Oryzias latipes: carcinogen dosage and time of exposure.
Topics: Animals; Azo Compounds; Carcinogens; Dose-Response Relationship, Drug; Female; Fishes; Liver; Liver | 1984 |
Comparative toxicity of chemotherapy following partial hepatectomy.
Topics: Animals; Carbon Dioxide; Dactinomycin; DNA; Doxorubicin; Drug Therapy, Combination; Hepatectomy; Liv | 1981 |
The acute effect of lead acetate on glucocorticoid regulation of tyrosine aminotransferase in hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Dexamethasone; Dose-Response Relationship, Drug; | 1995 |
Atrial natriuretic peptide inhibits growth of hepatoblastoma (HEP G2) cells by means of activation of clearance receptors.
Topics: 1-Methyl-3-isobutylxanthine; Atrial Natriuretic Factor; Carcinoma, Hepatocellular; Cell Division; Cy | 1993 |
Antibiotic C3368-A, a fungus-derived nucleoside transport inhibitor, potentiates the activity of antitumor drugs.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Biological Transport; Carc | 1995 |
Extracorporeal high-intensity focused ultrasound for VX2 liver tumors in the rabbit.
Topics: Animals; Autoradiography; Carcinoma; Female; Injections, Intra-Arterial; Liver Neoplasms; Male; Neop | 1995 |
Does preoperative chemotherapy for hepatic tumors have an adverse effect on hepatic proliferation after delayed liver resection?
Topics: Animals; Cisplatin; Combined Modality Therapy; DNA; Doxorubicin; Hepatectomy; Liver; Liver Neoplasms | 1994 |
Lymphocyte protein synthesis in vivo: a measure of activation.
Topics: Adult; Carbon Isotopes; Colorectal Neoplasms; Humans; Immunophenotyping; Interleukin-2; Leucine; Liv | 1994 |
Assembly pathway of avian infectious laryngotracheitis virus.
Topics: Animals; Carcinoma, Hepatocellular; Chickens; DNA, Viral; Herpesvirus 2, Gallid; Liver Neoplasms; Ma | 1993 |
The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor.
Topics: Animals; Autoradiography; Cell Division; Disease Models, Animal; DNA; Glucans; Granuloma; Immunohist | 1994 |
p53 mutations at A:T base pairs in angiosarcomas of vinyl chloride-exposed factory workers.
Topics: Adenine; Aged; Base Composition; Base Sequence; Carcinoma, Hepatocellular; DNA; Exons; Gene Amplific | 1994 |
Biological markers in hepatocellular carcinoma: potential clinical implications.
Topics: Antigens, Neoplasm; Biomarkers; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Collagenases; | 1993 |
Effects of epidermal growth factor on growth control and signal transduction pathways in different human hepatoma cell lines.
Topics: Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; DNA, Neoplasm; Dose-Response Relatio | 1993 |
Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Colorectal Neoplasms; Liver Neoplasms; Mevalonic Ac | 1996 |
Tumor-dependent activation of rodent hepatic stellate cells during experimental melanoma metastasis.
Topics: Actins; Animals; Biomarkers; Cell Movement; Cells, Cultured; Chemotactic Factors; Culture Media, Con | 1997 |
Importance of hepatic first-pass removal in metastasis of colon carcinoma cells.
Topics: Animals; Cell Line; Colonic Neoplasms; Humans; Kinetics; Liver Neoplasms; Male; Mathematics; Mice; M | 1998 |
Paclitaxel shows cytotoxic activity in human hepatocellular carcinoma cell lines.
Topics: Adolescent; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Dru | 1999 |
[3H]thymidine incorporation into whole liver as an alternative to [3H]thymidine incorporation into DNA as a parameter of cell proliferation in regenerating liver tissue in rats.
Topics: Animals; Cell Division; DNA; Hepatectomy; Liver; Liver Neoplasms; Liver Regeneration; Male; Rats; Ra | 1999 |
The role of cAMP-MAPK signalling in the regulation of human hepatocellular carcinoma growth in vitro.
Topics: Carcinoma, Hepatocellular; Cyclic AMP; GTP-Binding Proteins; Humans; In Vitro Techniques; Liver Neop | 1999 |
Increased GABAergic activity inhibits alpha-fetoprotein mRNA expression and the proliferative activity of the HepG2 human hepatocellular carcinoma cell line.
Topics: Albumins; alpha-Fetoproteins; Blotting, Northern; Carcinoma, Hepatocellular; Cell Division; Dose-Res | 2000 |
In vitro and in vivo inhibition of liver cancer cells by 1,25-dihydroxyvitamin D3.
Topics: Animals; Antineoplastic Agents; Calcitriol; Carcinoma, Hepatocellular; Cell Division; DNA, Neoplasm; | 2000 |
In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole.
Topics: Albendazole; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Count; Cell Cycle; Cell | 2001 |
beta-estradiol stimulation of DNA synthesis requires different PKC isoforms in HepG2 and MCF7 cells.
Topics: Androstadienes; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Division; Cell Membrane; DNA Repli | 2001 |
Effects of diallyl disulfide and other donors of sulfane sulfur on the proliferation of human hepatoma cell line (HepG2).
Topics: Allyl Compounds; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cystamine; Disulfi | 2001 |
Magnolol suppresses proliferation of cultured human colon and liver cancer cells by inhibiting DNA synthesis and activating apoptosis.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Calcium; Cell Cycle; Cell Cycle Pr | 2002 |
A cyclin-dependent kinase inhibitor (p21(WAF1/CIP1)) affects thymidine incorporation in human liver cancer cells.
Topics: Adenosine Triphosphate; Blotting, Northern; Blotting, Western; Carcinoma, Hepatocellular; CDC2-CDC28 | 2002 |
Hepatopoietin acts as an autocrine growth factor in hepatoma cells.
Topics: Aged; Autocrine Communication; Blotting, Western; Carcinoma, Hepatocellular; Cell Division; Enzyme-L | 2001 |
Pharmacology of beta-L-thymidine and beta-L-2'-deoxycytidine in HepG2 cells and primary human hepatocytes: relevance to chemotherapeutic efficacy against hepatitis B virus.
Topics: Antiviral Agents; Carcinoma, Hepatocellular; Chromatography, High Pressure Liquid; Deoxycytidine; Ha | 2002 |
Inhibition by ultraviolet irradiation of the glucocorticoid induction of tyrosine aminotransferase in bromodeoxyuridine-treated H-35 hepatoma.
Topics: Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Dexamethasone; Enzyme Indu | 1977 |
The effects of controlled substitution of 5-bromodeoxyuridine (BUdR) for thymidine in hepatoma cell DNA.
Topics: Acid Phosphatase; Alcohol Oxidoreductases; Aminopterin; Animals; Bromodeoxyuridine; Carcinoma, Hepat | 1977 |
The diverse effects of 5'-bromodeoxyuridine on enzyme activities in cultured H35 hepatoma cells.
Topics: Alanine Transaminase; Bromodeoxyuridine; Carboxy-Lyases; Carcinoma, Hepatocellular; Cell Line; Dexam | 1977 |
Early temporal changes in the uridine kinase isozyme profile of the Novikoff hepatoma in response to 5-azacytidine treatment.
Topics: Aging; Animals; Azacitidine; Carcinoma, Hepatocellular; DNA Replication; Dose-Response Relationship, | 1975 |
Macrophages activated as suspension cultures with lymphocyte mediators devoid of antigen become cytotoxic for tumor cells.
Topics: Animals; Ascitic Fluid; Carcinoma, Hepatocellular; Cattle; Cell Adhesion; Cell Migration Inhibition; | 1975 |
Biochemical effects of bleomycin A2 on Novikoff hepatoma ascites cells.
Topics: Ascitic Fluid; Bleomycin; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucl | 1975 |
The effect of several antitumor agents on 3H-TTP incorporation in host liver and hepatoma nuclei.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Camptothecin; Carcinoma, Hepatocellular; Cell Nucle | 1977 |
Cell cycle and growth stage-dependent changes in the transport of nucleosides, hypoxanthine, choline, and deoxyglucose in cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Choline; D | 1975 |
Effect of a normal serum protein absent from hepatoma-bearing animals on cell cultures.
Topics: Animals; Blood Proteins; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; Contact Inhibiti | 1975 |
Macrophages activated in vitro with lymphocyte mediators kill neoplastic but not normal cells.
Topics: Ascitic Fluid; BCG Vaccine; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line; Cells, Cultured; Ch | 1975 |
Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells.
Topics: Animals; Biological Transport, Active; Bucladesine; Carcinoma, Hepatocellular; Cell Division; Cell L | 1975 |
Repair methylation of parental DNA in synchronized cultures of Novikoff hepatoma cells.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxycytidine; DNA; | 1975 |
Biphasic induction of ornithine decarboxylase and putrescine levels in growing HTC cells.
Topics: Animals; Blood; Carbon Radioisotopes; Carboxy-Lyases; Carcinoma, Hepatocellular; Cattle; Cell Line; | 1975 |
[Regenerative growth of asvitic hepatoma 22A].
Topics: Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mice; Mice, Inbred C3H; Mitosis; Neoplasm Trans | 1975 |
Zinc intake, neoplastic DNA synthesis, and chemical carcinogenesis in rats and mice.
Topics: Animals; Carcinoma, Hepatocellular; Depression, Chemical; DNA, Neoplasm; Dose-Response Relationship, | 1975 |
The hepatic chalone. II. Chemical and biological properties of the rabbit liver chalone.
Topics: Aging; Animals; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Cells, Cultured; Deoxyribon | 1975 |
Rat hepatoma cells nucleolar DNA. 2. Analysis of nucleolar DNA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Centrifugation, Density Gradient; | 1975 |
[Corticosterone, a synchronizing factor for liver cells].
Topics: Carcinoma, Hepatocellular; Cell Division; Corticosterone; Culture Techniques; DNA; Humans; Liver; Li | 1975 |
Interaction of ultrasound with neoplastic tissue. II. Systemic effects after local sonic irradiation.
Topics: Adrenal Gland Neoplasms; Adrenal Glands; Animals; Kidney; Kidney Neoplasms; Liver; Liver Neoplasms; | 1976 |
[A kinetic analysis of the growth of transplanted tumors and their metastasis].
Topics: Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; DNA, Neoplasm; Kinetics; Liver Neoplasms; | 1975 |
Nucleotidase activity in regenerating liver and in clonal strains of hepatoma and pituitary cells in culture.
Topics: Adenine; Animals; Carcinoma, Hepatocellular; Cell Division; Clone Cells; DNA; Liver; Liver Neoplasms | 1976 |
Growth inhibition of cells in cultures and of vaccinia virus infected HeLa cells by derivatives of trifluorothymidine.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Depression, Chemical; HeLa Cells; Leuk | 1976 |
Inhibition of de novo pyrimidine nucleotide and DNA synthesis and growth of cultured Novikoff rat hepatoma cells and other cell lines by pyrazofurin (NSC 143095).
Topics: Adenosine; Amides; Anti-Bacterial Agents; Carcinoma, Hepatocellular; Cell Division; Cells, Cultured; | 1976 |
The mechanism of 5-fluorouridine toxicity in Novikoff hepatoma cells.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Cell Line; Deoxyribonucleosides; De | 1976 |
Enzyme pattern directed chemotherapy. The effects of combinations of methotrexate, 5-fluorodeoxyuridine and thymidine on rat hepatoma cells in vitro.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Depression, Chemical; Floxuridine; Liv | 1976 |
Utilization of 3H from deoxyuridine and thymidine for synthesis of DNA and tother macromolecules in various organs of the rat.
Topics: Animals; Bone Marrow; Carcinoma, Hepatocellular; Deoxyuridine; DNA; Fluorouracil; Intestinal Mucosa; | 1977 |
The application of rapid kinetic techniques to the transport of thymidine and 3-O-Methylglucose into Mammalian cells in suspension culture.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Cyanides; Cytosine; Dif | 1976 |
[Kinetics of cell proliferation and growth of transplanted hepatoma in mice].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Liver Neoplasms; Mice; Mitosis; | 1976 |
Antiproliferative activity of anti-inflammatory drugs in two mammalian cell culture lines.
Topics: Animals; Anti-Inflammatory Agents; Carcinoma, Hepatocellular; Cell Division; Cell Line; Cyclooxygena | 1977 |
Growth rate of cultured Novikoff rat hepatoma cells as a function of the rate of thymidine and hypoxanthine transport.
Topics: Adenosine; Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; | 1977 |
Synthesis and secretion of albumin by a synchronized rat hepatoma cell line.
Topics: Albumins; Carcinoma, Hepatocellular; Cell Cycle; Cell Line; Isoleucine; Liver Neoplasms; Mitosis; Pr | 1977 |
In vitro inhibition of tritiated thymidine uptake in Morris hepatoma cells by normal rat liver extract: a possible liver chalone.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Growth Inhibitors; In Vitro Techniques | 1977 |
Relationship between thymidine transport and phosphorylation in Novikoff rat hepatoma cells as analyzed by a rapid sampling technique.
Topics: Adenosine Triphosphate; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Kinetics | 1977 |
Transport and metabolism of deoxycytidine and 1-beta-D-arabinofuranosylcytosine into cultured Novikoff rat hepatoma cells, relationship to phosphorylation, and regulation of triphosphate synthesis.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultured; Cytarabine; Deoxy | 1978 |
Stimulatory effect of dimethylsulfoxide on [3H]thymidine incorporation into DNA in Novikoff hepatoma cells.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Dimethyl Sulfoxide; DNA, Neoplasm; Dose-Response Re | 1978 |
Low level of unscheduled [3H] thymidine incorporation into hyperplastic nodule and hepatoma cells after exposure to dimethylnitrosamine in vivo.
Topics: Animals; Carcinoma, Hepatocellular; Dimethylnitrosamine; DNA; DNA, Neoplasm; Hyperplasia; Liver; Liv | 1978 |
Tritiated thymidine as a broad spectrum initiator in transplacental two-stage carcinogenesis, with phorbol as promoter.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male | 1979 |
[Retention of non-dividing hepatocytes in growing mouse liver].
Topics: Animals; Carcinoma, Hepatocellular; Clone Cells; Liver; Liver Neoplasms; Liver Regeneration; Mice; M | 1979 |
Insulin induction of tyrosine aminotransferase in synchronized hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; DNA, Neoplasm; Enzyme Induction; Insul | 1975 |
Radiorespirometric analysis of glucose metabolism in the rat during feeding with 3'-methyl-4-(dimethylamino) azobenzene. -Radiorespirometry using [1-14C]glucose-.
Topics: Animals; Breath Tests; Carbon Radioisotopes; DNA, Neoplasm; Glucose; Glucosephosphate Dehydrogenase; | 1979 |
Effects of extracellular Ca2+ and Mg2+ on nucleic acids and proteins syntheses by tumor and normal liver cells.
Topics: Animals; Calcium; Cell Membrane Permeability; DNA; In Vitro Techniques; Leucine; Liver; Liver Neopla | 1978 |
Specific killing of line-10 cells in vitro in the presence of normal lymphoid cells and antibodies from immune rabbits or tumor-resistant guinea pigs.
Topics: Animals; Antibodies; Antibody Specificity; Antibody-Dependent Cell Cytotoxicity; Binding Sites, Anti | 1978 |
Purification of a protein inhibitor of DNA synthesis in cells of hepatic origin.
Topics: Animals; Antimetabolites; Cells, Cultured; DNA Replication; Liver; Liver Neoplasms; Male; Mice; Neop | 1976 |
[Effect of N-nitroso-N-methylurea on DNA and RNA synthesis in cells of liver and spleen tumors in leucosis L-1210].
Topics: Animals; DNA, Neoplasm; Leukemia L1210; Leukopenia; Liver Neoplasms; Methylnitrosourea; Mice; Mice, | 1976 |
Induction of Mn-superoxide dismutase by tumor necrosis factor, interleukin-1 and interleukin-6 in human hepatoma cells.
Topics: Antibodies; Carcinoma, Hepatocellular; Cell Division; Cell Line; DNA Replication; Enzyme Induction; | 1992 |
Expression and growth-promoting effect of adult T-cell leukemia-derived factor. A human thioredoxin homologue in hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Cell Division; Cytokines; Humans; Immunoblotting; Immunoenzyme Techniques | 1992 |
Endotoxins inhibit endocytotic catabolism of low-density lipoproteins in Hep G2 cells.
Topics: Biological Transport; Carcinoma, Hepatocellular; Cell Division; Cell Line; DNA Replication; Endocyto | 1992 |
A quantitative model for spontaneous bone metastasis: evidence for a mitogenic effect of bone on Walker 256 cancer cells.
Topics: Animals; Body Burden; Bone and Bones; Bone Neoplasms; Carcinoma 256, Walker; Cell Division; Female; | 1992 |
The exposure of carcinogen-initiated primary neonatal rat hepatocytes to tumor promoters modulates both the transcripts and the enzymatic activity of nuclear poly(ADP-ribose) polymerase.
Topics: Animals; Animals, Newborn; Benzamides; Calcium; Cell Cycle; Cell Nucleus; Cells, Cultured; Dimethyln | 1992 |
Metabolism of a novel antitumor agent, crisnatol, by a human hepatoma cell line, Hep G2, and hepatic microsomes. Characterization of metabolites.
Topics: Antineoplastic Agents; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Cell Line; Chromat | 1991 |
The effect of anti-alpha-fetoprotein-adriamycin conjugate on a human hepatoma.
Topics: alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Carcinoma, Hepatocellular; Cross-Linking Reagen | 1990 |
Inhibitory effects of acyclic retinoid (polyprenoic acid) and its hydroxy derivative on cell growth and on secretion of alpha-fetoprotein in human hepatoma-derived cell line (PLC/PRF/5).
Topics: Acrylates; Albumins; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Do | 1990 |
Fractional incorporation of radionucleotides, a marker of in vitro tumor cell chemosensitivity in colorectal cancer.
Topics: Antineoplastic Agents; Colorectal Neoplasms; Daunorubicin; DNA, Neoplasm; Doxorubicin; Humans; In Vi | 1991 |
Partial down-regulation of protein kinase C reverses the growth inhibitory effect of phorbol esters on HepG2 cells.
Topics: Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Down-Regulation; Gene Expression Reg | 1990 |
Incorporation of iododeoxyuridine into neoplastic DNA: a fraudulent magic bullet?
Topics: Cell Survival; Colonic Neoplasms; DNA, Neoplasm; Humans; Idoxuridine; Liver; Liver Neoplasms; Thymid | 1990 |
DNA synthesis, apoptosis, and phenotypic expression as determinants of growth of altered foci in rat liver during phenobarbital promotion.
Topics: Animals; Body Weight; Carcinogens; Cell Division; DNA Replication; Female; Liver; Liver Neoplasms; N | 1990 |
Effect of insulin on the growth of a human hepatoma cell line PLC/PRF/5: a possible role of insulin receptor.
Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Division; DNA, Neoplasm; Dose-Response Relations | 1988 |
Molecular dosimetry of DNA alkylation during chronic exposure to carcinogens.
Topics: Alkylation; Animals; Carcinogens; Cell Transformation, Neoplastic; Diethylnitrosamine; DNA; Dose-Res | 1987 |
Liposomes in chemo- and immunotherapy of cancer.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adenocarcinoma; Animals; Floxuridine; Liposomes; Liver; Liver Neo | 1987 |
Stimulation of the LDL receptor activity in the human hepatoma cell line Hep G2 by high-density serum fractions.
Topics: Blood; Carcinoma, Hepatocellular; Cell Line; Cholesterol; Fibroblasts; Humans; Hydroxymethylglutaryl | 1986 |
Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity.
Topics: Adenoviridae; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cri | 1986 |
Inhibition of the growth of human hepatocellular carcinoma in vitro and in athymic mice by a quinazoline inhibitor of thymidylate synthase, CB3717.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Deoxyuridine; Dose-Response Relationship, | 1986 |
Human lymphoblastoid interferon. In vitro and in vivo studies in hepatocellular carcinoma.
Topics: 2',5'-Oligoadenylate Synthetase; Animals; Carcinoma, Hepatocellular; Cell Line; HLA Antigens; Humans | 1986 |
Nutrition and aflatoxin carcinogenesis.
Topics: Aflatoxins; Aminopyrine; Animals; Benzopyrenes; Carcinogens; Carcinoma, Hepatocellular; Cell Transfo | 1971 |
[Specific stages in the growth of preneoplastic cells during carcinogenesis].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Cell Transformation, Neoplastic; | 1970 |
Lasiocarpine: factors influencing its toxicity and effects on liver cell division.
Topics: Acetates; Alkaloids; Amides; Aminopyrine; Animals; Chemical and Drug Induced Liver Injury; Dealkylat | 1971 |
Reduced activity of DNA polymerase prepared from bleomycin-treated cancer cells.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Carbon Isotopes; Carcinoma, Hepatocellular; Culture | 1971 |
Effect of various anticancer agents on DNA polymerase.
Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Bone | 1971 |
Expression of tyrosine aminotransferase activity in somatic-cell heterokaryons: evidence for negative control of enzyme expression.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Fusion; Cell Line; Cell Nucleus; Enzyme In | 1971 |
Single strand scission and repair of DNA in bleomycin-sensitive and resistant rat ascites hepatoma cells.
Topics: Animals; Bleomycin; Carcinoma, Hepatocellular; Cells, Cultured; Centrifugation, Density Gradient; Cy | 1973 |
Breakage of DNA-membrane complex by bleomycin.
Topics: Animals; Bleomycin; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Membrane; Centrifugation, | 1974 |
Contact inhibition and gene expression in HTC-L cell hybrid lines.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Fusion; Cell Line; Clone Cells; Complement | 1973 |
Suppression of DNA synthesis in hepatoma cells exposed to glucocorticoid hormone in vitro.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Depression, Chemical; Dexametha | 1973 |
Steroid receptors and the mechanism of the specificity of glucocorticoid responsiveness of somatic cell hybrids between hepatoma tissue culture cells and mouse fibroblasts.
Topics: Animals; Binding Sites; Binding, Competitive; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nu | 1974 |
Inhibition of messenger RNA accumulation but not translation in ultraviolet irradiated hepatoma cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Dactinomycin; DNA, Neoplasm; Dose-Response Relationsh | 1974 |
Hepatorenal lesions in rats fed a low lipotrope diet and exposed to aflatoxin.
Topics: Aflatoxins; Animals; Autoradiography; Body Weight; Choline; Diet; DNA; Hyperplasia; Kidney; Lipids; | 1968 |
[The strength of intercellular contacts and proliferative pool in mice hepatomas].
Topics: Animals; Carcinoma, Hepatocellular; Cell Membrane Permeability; DNA, Neoplasm; Liver; Liver Neoplasm | 1968 |
Growth kinetics of diethylnitrosamine-induced, enzyme-deficient "preneoplastic" liver cell populations in vivo and in vitro.
Topics: Adenosine Triphosphatases; Animals; Autoradiography; Carcinogens; Cell Division; Cell Transformation | 1972 |
Mixed lymphoid cell-tumor culture reaction. I. Stimulation of rat lymphoid cells yb liver cell strains malignantly transformed in vitro.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Transformation, Neoplastic; Cells, Cultured; In Vitro Techni | 1974 |
Comparative biochemistry of hepatomas. VI. Thymidine incorporation into DNA as a measure of hepatoma growth rate.
Topics: Animals; Biochemical Phenomena; Biochemistry; Carbon Isotopes; Carcinoma, Hepatocellular; DNA; Liver | 1966 |
Activities of DNA nucleotidyltransferases and other enzymes in cell-free preparations from hepatomas of different growth rates.
Topics: Adenine Nucleotides; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Cyt | 1966 |
Inhibition of DNA synthesis in ascites hepatoma cells by normal liver extract.
Topics: Animals; Azo Compounds; Carcinoma, Hepatocellular; DNA, Neoplasm; Electrophoresis; In Vitro Techniqu | 1966 |
Tissue specificity of histone phosphorylation.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Hepatectomy; Histones; Liver; Liver Neoplasms; Ma | 1967 |
Changes in nucleic acid metabolism of tumour cells under high pressure oxygen.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA; Hyperbaric Oxyge | 1967 |
Fluorinated pyrimidines. XXIX. Syntheses of 2',3'-dehydro-5-fluoro-2'-deoxyuridine and 2',3'-dideoxy-5-fluorouridine.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Escherichia coli; Floxuridine; HeLa Ce | 1967 |
DNA metabolism in liver and kidney tumors of different growth rates.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Deoxyuridine; DNA, Neoplasm; Kidney Neoplasms; | 1968 |
A growth regulating factor in rat liver.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Division; Culture Techniques; DNA; DNA Nuc | 1967 |
RNA-DNA hybrids formed by ribosomal RNA from a rat hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Cellulose; DNA; DNA, Neoplasm; Female; Filtration; Liver; Liver | 1968 |
[Histochemical studies on intracellular glycogen metabolism in AH l3 ascites tumor cells. 1. Autoradiographic study on the AH l3 cell cycle].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; DNA, Neoplasm; Female; Glycogen; Histocytochemi | 1967 |
[Histochemical studies on intracellular glycogen metabolism in AH 13 ascites tumor cells. 2. AH 13 cell cycle and intracellular reaction of glycogen, phosphorylase and UDPG-glycogen glucosyltransferase].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; DNA, Neoplasm; Female; Glucosyltransferases; Gl | 1967 |
[Local interactions of cells in cell complexes of ascitic hepatoma 22].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; DNA, Neoplasm; In Vitro Techniques; Liver Neopl | 1966 |
Activity of the cell-sap factor inhibiting DNA synthesis of rat ascites hepatoma cells in normal tissues, various malignant and minimal deviation hepatomas, as well as livers during the course of carcinogenesis.
Topics: Animals; Bone Marrow; Brain Chemistry; Carbon Isotopes; Carcinogens; Carcinoma, Hepatocellular; Cent | 1968 |
A comparison of the effects of x-radiation on the relative rates of incorporation of labelled thymidine and cytidine into mitochondrial and nuclear DNA of Morris hepatomas.
Topics: Carcinoma, Hepatocellular; Cell Nucleus; DNA, Neoplasm; Liver Neoplasms; Mitochondria; Neoplasms, Ex | 1968 |
Comparative incorporation of tritiated thymidine and cytidine into the mitochondrial and nuclear DNA and RNA of two transplantable hepatomas (3924a and h-35tc2) and host livers.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; DNA, Neoplasm; Liver; Liver Neoplasms; Mitochondri | 1968 |
The heterogeneity of DNA polymerases in rat liver and hepatomas.
Topics: Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Cattle; Centrifugation, Density Gradient | 1968 |
Comparative studies of fluorinated pyrimidines with various cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Deoxyuridine; Depression, Chemical; DNA, Neo | 1968 |
Variations in the cell cycle during azo dye hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; Cell Transformation, Neoplastic; Coloring Agents; | 1968 |
The fine structure of proliferating cells in preneoplastic rat livers during azo-dye carcinogenesis.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Nucleolus; Cell Nucleus; Cytoplasm; Liver | 1969 |
Rates of incorporation of tritium-labeled thymidine into the mitochondrial and nuclear DNA of normal rat liver, regenerating liver, and four hepatomas with different growth rates and their host livers.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; DNA; DNA Replication; In Vitro Techniques; Liver; | 1968 |
[Comparisons in vivo of the tritiated thymidine and uridine uptake by human normal and cancerous tissues].
Topics: Carcinoma, Hepatocellular; DNA, Neoplasm; Humans; Liver Neoplasms; RNA, Neoplasm; Thymidine; Tritium | 1968 |
Enzymes of thymidine triphosphate synthesis in selected Morris hepatomas.
Topics: Aminohydrolases; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Culture Techniques; I | 1969 |
The effect of esteroproteases from mouse submaxillary gland on the growth of rat hepatoma cells in tissue culture.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Division; Culture Techniques; DNA; Esteras | 1969 |
[The effect of hypophysectomy on the proliferative activity of normal and malignant tissue].
Topics: Adrenal Glands; Animals; Carcinoma, Hepatocellular; DNA, Neoplasm; Hypophysectomy; Kidney; Liver; Li | 1969 |
Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.
Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Cattle; Chick Embryo; Chromatography, Ion Exchan | 1969 |
The synthesis of deoxyribonucleic acid and nuclear proteins by rat hepatoma cells immediately after gamma irradiation.
Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; DNA, Neoplasm; Liver | 1969 |
Increased DNA polymerase activity in a series of rat hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Deoxyribonucleases; DNA; DNA Nucleotidyltransferases; Female; Li | 1969 |
Non-degraded incorporation of highly polymerized DNA and isolated metaphase chromosomes into cultured mammalian cells and replication of the incorporated heterologous chromosomes in the cultured cells.
Topics: Animals; Carcinoma, Hepatocellular; Chromosomes; Culture Techniques; DNA; Liver; Liver Neoplasms; Mi | 1969 |
The nature of inhibitors of DNA synthesis in rat-liver hepatoma cells.
Topics: Animals; Animals, Newborn; Antineoplastic Agents; Arginase; Arginine; Carbon Isotopes; Carcinoma, He | 1969 |
[Adenosine deaminase in cell metabolism. I. Relation between enzyme activity and rate of DNA synthesis in various rat tissues].
Topics: Aging; Aminohydrolases; Animals; Carcinoma, Hepatocellular; DNA Replication; Intestinal Mucosa; Inte | 1969 |
Some factors affecting carbohydrate metabolism in hepatic tissues of different growth rates.
Topics: Animals; Carbohydrate Metabolism; Carcinoma, Hepatocellular; DNA; Glucokinase; Glycerophosphates; Gl | 1969 |
The effects of local x irradiation on the relative rates of incorporation of thymidine-methyl-5-3H and cytidine-5-3H into mitochondrial and nuclear DNA of Morris hepatoma 3924A.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; DNA, Neoplasm; Liver Neoplasms; Methylation; Mitoc | 1969 |
In vivo replication of normal and tumor cells: relation to cancer chemotherapy.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Deoxyuridine; DNA; DNA, Neoplasm | 1969 |
The modification of labeled cytidine and thymidine incorporation into mitochondrial and nuclear DNA in normal liver, hepatoma 3924A and its host liver by isoproterenol.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; DNA; DNA, Neoplasm; Female; Isoproterenol; Liver; | 1969 |
Deoxycytidylate deaminase and related enzymes of thymidine triphosphate metabolism in hepatomas and precancerous rat liver.
Topics: Aminohydrolases; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Neoplasms, Experimental; | 1969 |
The cell cycles of three transplantable Morris hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Liver Neoplasms; Mitosis; Necro | 1970 |
Effects of phenethyl alcohol on transport reactions, nucleotide pools and macromolecular synthesis in Novikoff rat hepatoma cells growing in suspension culture.
Topics: Amino Acids; Animals; Benzene Derivatives; Biological Transport, Active; Carcinoma, Hepatocellular; | 1970 |
Effects of hydroxyurea and 6-mercaptopurine on growth and some aspects of carbohydrate metabolism in regenerating and neoplastic liver.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Glucokinase; Glucose; Hepatecto | 1970 |
The distribution and synthesis of DNA in two classes or rat liver nuclei during azo dye-induced hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; Diet; DNA, Neoplasm; Liver Neoplasms; Male; Neopla | 1970 |
[Determination, on histologic sections, of specific activities of H3-DNA and H3-RNA synthesized in vivo by normal and cancerous human tissues].
Topics: Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Gallbladder Neoplasms; Humans; Liver; Liver Neoplasms | 1969 |
DNA replication and degradation in mammalian tissues. V. A series of slow-growing rat renal tumors and a variety of human cancers.
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Col | 1969 |
Specific inhibition of tumor cell DNA synthesis in vitro by lymphocytes from peritoneal exudate of immunized syngeneic guinea pigs.
Topics: Animals; Carcinoma, Hepatocellular; Centrifugation, Zonal; DNA; Exudates and Transudates; Guinea Pig | 1970 |
The metabolism of hepatoma cell strains in an improved filter well apparatus.
Topics: Animals; Biopsy; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA | 1970 |
Effect of crystalline abrin on the biosynthesis of protein, RNA, and DNA in experimental tumors.
Topics: Animals; Antimetabolites; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA, Neoplasm; Hot Te | 1970 |
Development of resistance of Novikoff hepatoma to 5-fluoro-2'-deoxyuridine.
Topics: Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Floxuridine; Liver Ne | 1970 |
Liver regeneration and induction of hepatomas in B6AF mice by urethan.
Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DNA; Female; Hepatectomy; Liver Neoplasms; Liver Re | 1970 |
Specific stages of cellular response to homeostatic control during diethylnitrosamine-induced liver carcinogenesis.
Topics: Adenosine Triphosphatases; Animals; Autoradiography; Carcinogens; Carcinoma, Hepatocellular; Cell Tr | 1970 |
Nature of rat liver cell sap factors inhibiting the DNA synthesis in tumour cells.
Topics: Animals; Animals, Newborn; Arginase; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocel | 1971 |
DNA replication patterns in chromosomes of several transplantable ascites hepatomas of the rat.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Carcinoma, Hepatocellular; Chromosomes; DN | 1971 |
A preliminary report on the thymidine labeling indices and kinetics of cell proliferation in selected Morris hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; DNA, Neoplasm; Female; Kinetics; Liver Neoplasms; | 1970 |
Cytochalasin B. I. Effect on cytokinesis of Novikoff hepatoma cells.
Topics: Animals; Antineoplastic Agents; Benzocycloheptenes; Carcinoma, Hepatocellular; Cell Division; Cholin | 1971 |
Some metabolic effects of halothane on mammalian tissue culture cells in vitro.
Topics: Acetates; Animals; Autoradiography; Carbon Isotopes; Carcinoma, Hepatocellular; Culture Techniques; | 1971 |
Nucleotide pools of Novikoff rat hepatoma cells growing in suspension culture. I. Kinetics of incorporation of nucleosides into nucleotide pools and pool sizes during growth cycle.
Topics: Animals; Aspartic Acid; Biological Transport; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; | 1971 |
Bilirubin toxicity in hepatoma cells.
Topics: Animals; Bilirubin; Binding Sites; Carcinoma, Hepatocellular; Cattle; Cell Line; Culture Techniques; | 1971 |
[Mitochondrial DNA-polymerase from tumor and normal tissues].
Topics: Animals; Ascites; Carcinoma, Hepatocellular; DNA Nucleotidyltransferases; Embryo, Mammalian; Liver N | 1970 |
Activation of host lymphocytes cultured with cancer cells treated with neuraminidase.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Culture Tec | 1971 |
Absence of an effect of partial hepatectomy on aflatoxin B 1 carcinogenesis.
Topics: Aflatoxins; Animals; Body Weight; Carcinoma, Hepatocellular; Cell Nucleus; Hepatectomy; Liver; Liver | 1971 |
Behavior of opposing pathways of thymidine utilization in differentiating, regenerating, and neoplastic liver.
Topics: Animals; Animals, Newborn; Carbon Dioxide; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Differen | 1971 |
Cell proliferation and tumor growth in hepatomas 3924A.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Connective Tissue; Female; Liver Neoplasms; Mit | 1971 |
Effect of polyenic antibiotics on Ehrlich ascites and Novikoff hepatoma cells.
Topics: Animals; Antibiotics, Antineoplastic; Antifungal Agents; Carbon Isotopes; Carcinoma, Ehrlich Tumor; | 1971 |
[Selective inhibition of DNA synthesis and tumorigenesis by 7,12-dimethylbenz(a)anthracene in regenerating rat liver].
Topics: Animals; Benz(a)Anthracenes; Carbon Isotopes; Carcinoma, Hepatocellular; Depression, Chemical; DNA; | 1970 |
Nucleolar and extranucleolar chromatin of rat Novikoff hepatoma cells. A comparison of histone and non-histone protein acetylation.
Topics: Acetates; Animals; Ascitic Fluid; Blood; Carbon Isotopes; Carcinoma, Hepatocellular; Cattle; Cell Nu | 1971 |
Non-essential amino acid requirements of mammalian cells in tissue culture.
Topics: Amino Acids; Animals; Autoradiography; Carcinoma; Carcinoma, Hepatocellular; Cell Division; Cell Lin | 1971 |
DNA synthesis and the effect of sucrose in nuclei of host liver and Morris hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradie | 1971 |
Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2-acetylaminofluorene.
Topics: Acetates; Amides; Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Cell Transform | 1971 |
The metabolic effects of nonvolatile anesthetics on mammalian hepatoma cells in vitro. II. Inhibition of macromolecular precursor incorporation.
Topics: Amobarbital; Animals; Carcinoma, Hepatocellular; Culture Techniques; DNA, Neoplasm; Leucine; Lidocai | 1971 |
Control of gene expression in carbohydrate, pyrimidine and DNA metabolism.
Topics: Animals; Animals, Newborn; Carbohydrate Metabolism; Carcinoma, Hepatocellular; Cell Differentiation; | 1970 |
Diet and aflatoxin B 1 toxicity in rats.
Topics: Acid Phosphatase; Aflatoxins; Aminopyrine; Animals; Anisoles; Benzopyrenes; Carcinoma, Hepatocellula | 1971 |
Nucleoside transport by Novikoff rat hepatoma cells glowing in suspension culture. Specificity and mechanism of transport reactions and relationship to nucleoside incorporation into nucleic acids.
Topics: Adenosine; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chloromercur | 1971 |
Effects of 3'deoxyadenosine (cordycepin) and 2'deoxyadenosine on nucleoside transport, macromolecular synthesis, and replication of cultured Novikoff hepatoma cells.
Topics: Adenosine; Adenosine Triphosphate; Amino Acids; Animals; Biological Transport; Carcinoma, Hepatocell | 1971 |
Twenty-four-hour variations in DNA synthesis of a fast-growing and a slow-growing hepatoma: DNA synthesis rhythm in hepatoma.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Circadian Rhythm; DNA, Neoplasm; Liver Neoplasm | 1971 |
Mechanism of inhibition of ribonucleoside diphosphate reductase by a-(N)-heterocyclic aldehyde thiosemicarbazones.
Topics: Animals; Binding Sites; Carcinoma, Hepatocellular; Cytosine Nucleotides; DNA, Neoplasm; Formaldehyde | 1971 |
Glycogen metabolism in regenerating liver and liver neoplasms.
Topics: Adenosine Monophosphate; Animals; Carcinoma, Hepatocellular; Cysteine; DNA; Glucose-6-Phosphatase; G | 1972 |
DNA synthesis in Morris hepatoma 9618A and in host liver following partial hepatectomy in rats adapted to controlled feeding schedules.
Topics: Animals; Carcinoma, Hepatocellular; Circadian Rhythm; DNA; DNA, Neoplasm; Feeding Behavior; Hepatect | 1972 |
Cell proliferation in cancer.
Topics: Acute Disease; Animals; Autoradiography; Bone Marrow Cells; Carcinoma, Hepatocellular; Carcinoma, Sq | 1968 |
Effects of partial hepatectomy in rats on two transplantable hepatomas. Changes in weight and in synthesis of DNA and ferritin.
Topics: Animals; Autoradiography; Body Weight; Carcinoma, Hepatocellular; DNA, Neoplasm; Female; Ferritins; | 1971 |
[Thymidine and thymidilate kinases from transplantable rat tumors and homologous tissues].
Topics: Animals; Ascites; Carcinoma, Hepatocellular; Kidney; Liver; Liver Neoplasms; Liver Regeneration; Neo | 1971 |
Studies on tritiated thymidine incorporation into DNA molecules by electron microscopic autoradiography.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cells, Cultured; DNA; DNA, Neoplasm; Liver Neop | 1971 |
Biochemical approaches to prediction of response in solid tumors.
Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Carcinoma, Squamo | 1971 |
Histone phosphorylation and DNA synthesis are linked in synchronous cultures of HTC cells.
Topics: Benzocycloheptenes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; DNA; Electrophoresis; His | 1972 |
Capillary tube scanning applied to cell growth kinetics.
Topics: Animals; Bromodeoxyuridine; Carcinoma, Hepatocellular; Cell Biology; Cell Count; Cells; Cells, Cultu | 1972 |
Lack of correlation between poly ADP-ribose formation and DNA synthesis.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cell Nucleus; DNA; DNA Nucleotidyltran | 1971 |
Lymphocyte blastogenic responses to cultured allogeneic tumor cells in vitro.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Count; Cells, Cultured; Female; Hu | 1972 |
Inhibition of the transport of several hexoses in mammalian cells by cytochalasin B.
Topics: Aminoisobutyric Acids; Animals; Biological Transport; Calcium; Carbon Isotopes; Carcinoma, Hepatocel | 1972 |
Changes in chromatin caused by aminoazo compounds.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Chromatin; DN | 1972 |
Tumor cell sap factor stimulating orotate incorporation into nucleic acids in ascites hepatoma cells.
Topics: Aging; Animals; Animals, Newborn; Carbon Isotopes; Carcinoma, Hepatocellular; Cytoplasm; Diphosphate | 1972 |
[Influence of neoplasm growth on the plasma copper and ceruloplasmin levels in the rat].
Topics: Analysis of Variance; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Ceruloplasmin; Copp | 1972 |
Polynucleotide ligase in rat tissues and ascites hepatoma.
Topics: Animals; Carcinoma, Hepatocellular; Chromatography; Deoxyribonucleases; DNA; DNA Repair; Kidney; Lig | 1972 |
Turnover of deoxyribonucleic acid, histones, and lysine-rich histone phosphate in hepatoma tissue culture cells.
Topics: Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Half-Life; | 1972 |
The synergistic effect of hypoglycemia and L-asparaginase upon transplantable hepatomas of varying growth rates.
Topics: Animals; Asparaginase; Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Escherichia coli; Glucos | 1972 |
Cell loss and proliferation induced by N-2-fluorenylacetamide in the rat liver in relation to hepatoma induction.
Topics: Acetamides; Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Cell Survival; Diet; | 1972 |
Effect of hydrocortisone on the synthesis of DNA and histones and the acetylation of histones in regenerating liver.
Topics: Acetates; Acylation; Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Nucleus; Chromatograp | 1972 |
Studies on the inhibition by ethionine of aminoazo dye carcinogenesis in rat liver.
Topics: Administration, Oral; Animals; Appetite; Carbon Isotopes; Carcinoma, Hepatocellular; DNA, Neoplasm; | 1972 |
[Minor role of the de novo pathway in the biosynthesis of RNA during fetal and neoplastic liver development in rats].
Topics: Aflatoxins; Age Factors; Animals; Carcinoma, Hepatocellular; Cyclic AMP; Female; Glucagon; Injection | 1972 |
Cell-mediated tumor immunity measured in vitro and in vivo with soluble tumor-specific antigens.
Topics: Animals; Antigens, Neoplasm; Ascitic Fluid; Biological Assay; Carcinoma, Hepatocellular; Cell Migrat | 1972 |
Impaired inflammatory response in tumor-bearing guinea pigs.
Topics: Animals; Antigen-Antibody Reactions; Autoradiography; Bone Marrow; Bone Marrow Cells; Carcinoma, Hep | 1972 |
Alteration of properties of cell contacts during progression of hepatomas.
Topics: Animals; Calcium; Carcinoma, Hepatocellular; Cations, Divalent; Cell Adhesion; Cell Separation; Cont | 1973 |
Thymidine transport by cultured Novikoff hepatoma cells and uptake by simple diffusion and relationship to incorporation into deoxyribonucleic acid.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell-Free System; Chloromercuri | 1972 |
Cytochalasin B. VI. Competitive inhibition of nucleoside transport by cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cells, Cultured; Choline; DNA, Neoplasm; I | 1972 |
Effect of fast-growing transplantable hepatoma on cell proliferation in host tissue of the mouse.
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; DNA, Neoplasm; Epithelial Cells; Epithelium; Fe | 1973 |
Decline in mixed lymphocyte reactivity of spleen cells from aged mice of a long-lived strain.
Topics: Age Factors; Animals; Carcinoma; Carcinoma, Hepatocellular; Liver Neoplasms; Lung Neoplasms; Lymphoc | 1973 |
Inhibition of DNA synthesis of synchronized cells by liver extracts acting in G1 phase.
Topics: Animals; Carcinoma, Hepatocellular; Cell Count; Cell Division; Cells, Cultured; DNA, Neoplasm; Liver | 1973 |
Tripeptide in human serum which prolongs survival of normal liver cells and stimulates growth in neoplastic liver.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; DNA; DNA, Neoplasm; Growth Substances; Humans; | 1973 |
Action of miracil D and related compounds on DNA and RNA synthesis in regenerating liver and hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; DNA; Hepatectomy; Liver Neoplasms; Liver Regeneration; Lucanthon | 1972 |
Thymidine as one of the factors in a beef liver extract decreasing 3 H-thymidine incorporation into DNA.
Topics: Animals; Carcinoma, Hepatocellular; Cattle; Chromatography, Gel; DNA; Growth Inhibitors; HeLa Cells; | 1973 |
DNA-dependent RNA polymerase from Ehrlich ascites tumor cells. I. Partial purification and characterization of RNA polymerase II.
Topics: Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Cattle; Deoxyribonucl | 1973 |
Inhibitory effect of a streptococcal preparation (OK-432) on the nucleic acid synthesis in tumor cells in vitro.
Topics: Animals; Carcinoma; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; DNA, Neoplasm; HeLa Cells; | 1973 |
Rapid arrest of DNA synthesis by N 6 ,O 2' -dibutyryl cyclic adenosine 3',5'-monophosphate in cultured hepatoma cells.
Topics: Autoradiography; Butyrates; Carcinoma, Hepatocellular; Cells, Cultured; Cyclic AMP; Deoxyadenosines; | 1973 |
Folate deficiency in rats bearing the Walker tumor 256 and the Novikoff hepatoma.
Topics: Adenine; Animals; Carcinoma 256, Walker; Carcinoma, Hepatocellular; Choline; Diet; FIGLU Test; Folic | 1973 |
Inhibition of hypoxanthine transport by chlorpromazine and SKF 525-A in cell culture.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Cells, Cultured; Chlorpromazine; Fibroblasts; H | 1973 |
5'-Nucleotide phosphodiesterase isoenzyme pattern in the serum of human hepatoma.
Topics: Adenoma; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Fetal Proteins; Floxuridine | 1973 |
The protective effect of estradiol-17 beta against polycyclic hydrocarbon cytotoxicity.
Topics: Animals; Azo Compounds; Benz(a)Anthracenes; Breast; Carcinoma, Hepatocellular; Cell Division; Cell T | 1973 |
Combined enzyme histochemical and radioautographic studies on areas of hyperplasia in the liver of rats fed N-2-fluorenylacetamide.
Topics: Adenosine Triphosphatases; Animals; Autoradiography; Fluorenes; Glucose-6-Phosphatase; Glucuronidase | 1973 |
Effects of formamidoxime on macromolecular synthesis in regenerating liver and hepatomas.
Topics: Amino Acids; Animals; Carcinoma, Hepatocellular; Cell Nucleus; Cytoplasm; Depression, Chemical; DNA; | 1973 |
Letter: On the source of "minor thymine" in DNA from a Novik off rat hepatoma cell line.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chromatography, Paper; Cytosine; Deamination; Deoxycy | 1973 |
The metabolic effects of halothane on mammalian hepatoma cells in vitro. II. Inhibition of DNA synthesis.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cells, Cultured; Depression, Chemical; DNA | 1973 |
Effect of actinomycin D on uptake and incorporation of thymidine and hypoxanthine into the acid-soluble and acid-insoluble fractions of rat hepatoma cells grown in culture.
Topics: Animals; Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; Dactinomycin; Dose-Response Rela | 1974 |
Unidirectional loss of human chromosomes in rat-human hybrids.
Topics: Aminopterin; Animals; Azaguanine; Carcinoma, Hepatocellular; Cell Fusion; Cell Line; Chromosomes; Cl | 1973 |
Incorporation and replication of foreign metaphase chromosomes in cultured mammalian cells.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chromosome Aberrations; Chromosomes; | 1973 |
Thymidine transport by Novikoff rat hepatoma cells synchronized by double hydroxyurea treatment.
Topics: Animals; Biological Transport, Active; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Chroma | 1974 |
[Kinetics of the cell proliferation of a slowly growing highly differentiated mouse hepatoma].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Kinetics; | 1973 |
Competitive inhibition of the transport of nucleosides, hypoxanthine, choline and deoxyglucose by theophylline, papaverine and prostaglandins.
Topics: Animals; Binding, Competitive; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultu | 1974 |
Alpha-(N)-heterocyclic carboxaldehyde thiosemicarbazone inhibitors of ribonucleoside diphosphate reductase.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cytidine; Deoxyribonucleotides; DNA, Neop | 1974 |
Intracellular conversions of deoxyribonucleosides by Novikoff rat hepatoma cells and effects of hydroxyurea.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; Cycloheximide; Cytidine; Deamination | 1974 |
The deoxyribonucleoside transport systems of cultured Novikoff rat hepatoma cells.
Topics: Animals; Biological Transport; Carcinoma, Hepatocellular; Cell Line; Cell Membrane Permeability; Cel | 1974 |
A comparison of the utilization of thymine and thymidine for the synthesis of DNA-thymine in Novikoff hepatoma cells.
Topics: Alkylating Agents; Carcinoma, Hepatocellular; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxy | 1974 |
Synthesis of some trinucleoside monophosphates of biological interest.
Topics: Animals; Biodegradation, Environmental; Bromodeoxyuridine; Carcinoma, Hepatocellular; Chromatography | 1974 |
Loss of serum protein from hepatoma-bearing animals.
Topics: Animals; Blood Proteins; Carcinoma, Hepatocellular; Chromatography, DEAE-Cellulose; Dietary Proteins | 1974 |
DNA and nucleoprotein changes in liver and tumor nuclei after irradiation.
Topics: Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Fractionation; Cell Nucleus; DNA, Neo | 1974 |
Further studies of histone phosphorylation in the presence of inhibitors of DNA synthesis.
Topics: Carcinoma, Hepatocellular; Cells, Cultured; Cycloheximide; DNA, Neoplasm; Enzyme Activation; Histone | 1974 |
Potential antitumor agents. 10. Synthesis and biochemical properties of 5-N-alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline thiosemicarbazones.
Topics: Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Hepatocellular; Depression, Chemical; DNA, | 1974 |
Separation of newly synthesized nucleohistone by equilibrium centrifugation in cesium chloride.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cesi | 1974 |
The stimulatory effect of a serum factor on DNA and protein synthesis in hepatoma cells.
Topics: Animals; Blood Proteins; Carcinoma, Hepatocellular; Cells, Cultured; DNA, Neoplasm; Electrophoresis, | 1974 |
Incorporation of precursors and inhibitors of nucleic acid synthesis into hepatomas and liver of the rat.
Topics: Amino Acids; Animals; Carbon Radioisotopes; Carcinoma, Hepatocellular; Cell Line; Fluorouracil; Inje | 1974 |
Changes in cell mediated immune functions by growing tumor.
Topics: Animals; Antibody Formation; Antibody-Producing Cells; Ascitic Fluid; Carcinoma, Hepatocellular; Cel | 1974 |
Dynamics of alpha-fetoprotein production compared to alpha 2-macroglobulin during induction of primary hepatoma with 4-dimethylaminoazobenzene in rats.
Topics: Animals; Autoradiography; Blood Proteins; Carcinoma, Hepatocellular; DNA, Neoplasm; Female; Fetal Pr | 1974 |
Appearance of alpha-fetoprotein in rat serum during induction of primary hepatoma with regard to development of histological changes in liver tissue.
Topics: Adenoma, Bile Duct; Animals; Autoradiography; Carcinoma, Hepatocellular; Cell Division; Cell Nucleus | 1974 |
[Determination of the cell cycle phases in heterogeneous tumor cell populations in vivo].
Topics: Animals; Autoradiography; Carcinoma, Hepatocellular; DNA, Neoplasm; Liver Neoplasms; Male; Mitosis; | 1969 |
The appearance and disappearance of the post-transcriptional repressor of tyrosine aminotransferase synthesis during the HTC cell cycle.
Topics: Animals; Benzocycloheptenes; Carcinoma, Hepatocellular; Cell Line; Dexamethasone; DNA; Enzyme Induct | 1970 |
Superinduction of tyrosine aminotransferase by actinomycin D in rat hepatoma (HTC) cells.
Topics: Animals; Antibodies; Carbon Isotopes; Carcinoma, Hepatocellular; Cell Line; Culture Techniques; Dact | 1970 |
Differential effect of 5-bromodeoxyuridine on the concentrations of specific enzymes in hepatoma cells in culture.
Topics: Acid Phosphatase; Alanine Transaminase; Alcohol Oxidoreductases; Animals; Bromodeoxyuridine; Carcino | 1971 |
[Relations between changes of plasma copper content and growth of Morris hepatoma 3924].
Topics: Activation Analysis; Animals; Carcinoma, Hepatocellular; Copper; Liver; Liver Neoplasms; Male; Manga | 1972 |
Effects of derivatives of cyclic 3',5'-adenosine monophosphate on the growth, morphology, and gene expression of hepatoma cells in culture.
Topics: Adenine Nucleotides; Adenosine Monophosphate; Agglutination Tests; Animals; Butyrates; Carcinoma, He | 1972 |
Early changes induced in rat liver by methylazoxymethanol acetate: mitotic abnormalities and polyploidy.
Topics: Animals; Azo Compounds; Carcinogens; Chromosome Aberrations; Chromosomes; DNA, Neoplasm; Liver; Live | 1974 |
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radi | 1974 |
DNA synthesis in rat liver during early stages of azo dye-induced hepatocarcinogenesis.
Topics: Animals; Autoradiography; Cell Division; Cell Transformation, Neoplastic; DNA, Neoplasm; Liver; Live | 1972 |
Evidence for DNA repair synthesis and turnover in rat liver following ingestion of 3'-methyl-4-dimethylaminoazobenzene.
Topics: Animals; Carbon Isotopes; Cell Fractionation; Cell Nucleus; Centrifugation, Density Gradient; DNA; D | 1972 |
Metabolic imbalance in carbohydrate, pyrimidine and ornithine utilization.
Topics: Animals; Carbohydrate Metabolism; Diabetes Mellitus; Liver Neoplasms; Ornithine; Pyrimidines; Rats; | 1972 |
Changes in the composition of rat liver chromatin fractions during diethylnitrosamine carcinogenesis.
Topics: Animals; Calcium; Chromatin; Electrophoresis, Polyacrylamide Gel; Liver; Liver Neoplasms; Molecular | 1972 |
Cell proliferation, RNA and protein synthesis during carcinogenesis in the rat liver.
Topics: Animals; Autoradiography; Cell Division; Cytidine; Liver Neoplasms; Male; Neoplasm Proteins; Neoplas | 1973 |
Rapid loss of 7-methylguanine from liver nucleic acids in mice during the initial stage of liver carcinogenesis induced by dimethylnitrosamine.
Topics: Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; DNA; Drinking Behavior; Guanine; Half-L | 1974 |
Mitotic blockage at G2 after partial hepatectomy during 4-dimethylaminoazobenzene hepatocarcinogenesis.
Topics: Animals; Autoradiography; Cell Division; DNA; Hepatectomy; In Vitro Techniques; Liver; Liver Neoplas | 1965 |
[Cell proliferation in early stages of liver carcinogenesis induced by 3-methyl-4-dimethylaminoazobenzene].
Topics: Animals; Autoradiography; Cell Division; Liver Neoplasms; Male; Neoplasms, Experimental; p-Dimethyla | 1971 |
Sex differences in cell proliferation and N-hydroxy-2-acetylaminofluorene sulfotransferase levels in rat liver during 2-acetylaminofluorene administration.
Topics: Acetamides; Animals; Body Weight; Carcinogens; DNA; Female; Fluorenes; Liver; Liver Neoplasms; Male; | 1972 |
Combination of enzyme histochemistry and radioautography: a new method applied to analysis of hepatocarcinogenesis.
Topics: Animals; Autoradiography; Carcinogens; Fluorenes; Histocytochemistry; Liver; Liver Neoplasms; Method | 1972 |
[A DNA-synthesis inhibiting substance in the human tumor tissues].
Topics: Amnion; Cell Line; Cell-Free System; Chondroitin; DNA, Neoplasm; Heparin; Humans; Hyaluronic Acid; L | 1971 |
Carcinoma, thymidine uptake, and mitosis in the livers of rats exposed to aflatoxin.
Topics: Aflatoxins; Animals; Autoradiography; Carcinogens; Chemical and Drug Induced Liver Injury; Dimethyl | 1968 |
The effect of L-asparaginase on mitotic activity during N-2-fluorenylacetamide hepatocarcinogenesis: subpopulations of nodular cells.
Topics: Acetates; Amides; Animals; Asparaginase; DNA; Fluorenes; Hepatectomy; Hyperplasia; Liver Neoplasms; | 1971 |
[Incorporation of radioactive precursors into chromsomal, nucleolar and mitochondrial DNA of normal liver and in liver undergoing canceration].
Topics: Animals; Cell Nucleolus; Chromosomes; DNA; Liver; Liver Neoplasms; Mitochondria, Liver; Neoplasms; N | 1968 |
[Liver regeneration following diethylnitrosamine poisoning].
Topics: Animals; Carcinogens; DNA; Female; Liver; Liver Neoplasms; Liver Regeneration; Mitosis; Nitrosamines | 1968 |
The effects of X-rays on a human tumour growing in organo-typic culture.
Topics: Autoradiography; Cells, Cultured; Culture Media; DNA, Neoplasm; Humans; Liver Neoplasms; Mitosis; Or | 1968 |