Page last updated: 2024-11-06

thymidine and Liver Cirrhosis

thymidine has been researched along with Liver Cirrhosis in 66 studies

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to assess whether prolonged telbivudine treatment improves liver inflammation and fibrosis."9.20Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B. ( Bao, W; Chen, C; Dong, Y; Goodman, Z; Hou, JL; Jia, J; Naoumov, NV; Niu, J; Ren, H; Shi, G; Tan, D; Trylesinski, A; Wan, M; Wang, Q; Wang, Y; Wei, L; Xie, Q; Xu, D, 2015)
"There is limited data on the efficacy and outcome of telbivudine (LdT) therapy in patients with chronic hepatitis B and compensated cirrhosis."9.19Comparing the efficacy and clinical outcome of telbivudine and entecavir naïve patients with hepatitis B virus-related compensated cirrhosis. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lin, MT; Tsai, MC; Tseng, PL; Yen, YH; Yu, HC, 2014)
"To study the therapeutic efficacy of 48-week telbivudine treatment on cirrhosis resulting from chronic hepatitis B."9.14[Telbivudine treatment on cirrhosis resulting from chronic hepatitis B]. ( Han, T; Liang, J; Xiao, SX, 2009)
" In this study, we reported a CHB patient with decompensated cirrhosis showing a significant improvement in massive proteinuria along with elevation of estimated glomerular filtration rate (eGFR) after 1 year treatment with telbivudine."7.85Improvement of telbivudine on renal function and massive proteinuria: A case report. ( Liu, J; Yao, N; Zhao, Y, 2017)
"Thirty-six HBeAg-positive patients with chronic hepatitis B (CHB) were enrolled for 52-week telbivudine monotherapy and were followed at treatment week (TW)-0, 4, 12, 24 and 52."7.81Telbivudine therapy may shape CD4(+) T-cell response to prevent liver fibrosis in patients with chronic hepatitis B. ( Jia, M; Jiang, W; Li, J; Li, L; Liu, Y; She, W; Wang, J, 2015)
"This study was aimed to evaluate the long-term effects of telbivudine (LdT) in the treatment of chronic hepatitis B (CHB) and HBV-related liver cirrhosis (LC) and to observe the changes of immunological responses during LdT treatment."7.81Efficacy of telbivudine in the treatment of chronic hepatitis b and liver cirrhosis and its effect on immunological responses. ( Gao, X; Liu, P; Lu, XD; Lu, YQ; Meng, N; Tang, WX; Wang, M; Yan, W; Zhang, SJ, 2015)
"Data are limited for comparison of the long-term efficacy of telbivudine (LdT) between hepatitis B virus (HBV)-related compensated and decompensated cirrhosis."7.80Comparison of telbivudine efficacy in treatment-naive patients with hepatitis B virus-related compensated and decompensated cirrhosis in 96 weeks. ( Li, J; Liu, J; Lu, W; Wang, J; Yang, X; Zhou, L, 2014)
"The aim of this study was to evaluate the efficacy and safety of telbivudine 600 mg/day compared with lamivudine 100 mg/day for 48 weeks of treatment in patients with hepatitis B-related cirrhosis."7.79Forty-eight-week retrospective study of telbivudine and lamivudine treatment in patients with hepatitis B-related cirrhosis. ( Chen, Y; Gao, Z; Han, Y; Han, Z; Jia, G; Li, C; Liu, J; Luo, G; Shi, Y; Xia, L; Yin, F; Zhou, X; Zhu, J, 2013)
" The aim of this study was to assess whether prolonged telbivudine treatment improves liver inflammation and fibrosis."5.20Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B. ( Bao, W; Chen, C; Dong, Y; Goodman, Z; Hou, JL; Jia, J; Naoumov, NV; Niu, J; Ren, H; Shi, G; Tan, D; Trylesinski, A; Wan, M; Wang, Q; Wang, Y; Wei, L; Xie, Q; Xu, D, 2015)
"There is limited data on the efficacy and outcome of telbivudine (LdT) therapy in patients with chronic hepatitis B and compensated cirrhosis."5.19Comparing the efficacy and clinical outcome of telbivudine and entecavir naïve patients with hepatitis B virus-related compensated cirrhosis. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lin, MT; Tsai, MC; Tseng, PL; Yen, YH; Yu, HC, 2014)
"To study the therapeutic efficacy of 48-week telbivudine treatment on cirrhosis resulting from chronic hepatitis B."5.14[Telbivudine treatment on cirrhosis resulting from chronic hepatitis B]. ( Han, T; Liang, J; Xiao, SX, 2009)
"The aim of this prospective study was to investigate the diagnostic value of ultrasound elastography for evaluating liver stiffness measurement (LSM) in 74 patients with hepatitis B virus (HBV) infection, treated with telbivudine (22 with chronic HBV infection, 32 with compensated cirrhosis and 20 with decompensated cirrhosis)."5.14The diagnostic value of ultrasound elastography in patients with hepatitis B virus infection: a prospective study. ( Bai, XF; Gou, YZ; Jiang, W; Liu, B; Yu, HT, 2010)
"Among the six drugs licensed for the treatment of chronic hepatitis B in the US, the preferred agents in 2008 will include entecavir, peginterferon alfa-2a, possibly telbivudine, and tenofovir following licensure."4.84Review article: current antiviral therapy of chronic hepatitis B. ( Ayoub, WS; Keeffe, EB, 2008)
" In this study, we reported a CHB patient with decompensated cirrhosis showing a significant improvement in massive proteinuria along with elevation of estimated glomerular filtration rate (eGFR) after 1 year treatment with telbivudine."3.85Improvement of telbivudine on renal function and massive proteinuria: A case report. ( Liu, J; Yao, N; Zhao, Y, 2017)
"A total of 546 consecutive cirrhotic patients treated with entecavir (n = 359), telbivudine (n = 104), or tenofovir (n = 83) for chronic hepatitis B were enrolled."3.85Long-term outcomes of hepatitis B virus-related cirrhosis treated with nucleos(t)ide analogs. ( Chen, CH; Hu, TH; Hung, CH; Lee, CM; Lu, SN; Tsai, MC; Wang, JH, 2017)
"Thirty-six HBeAg-positive patients with chronic hepatitis B (CHB) were enrolled for 52-week telbivudine monotherapy and were followed at treatment week (TW)-0, 4, 12, 24 and 52."3.81Telbivudine therapy may shape CD4(+) T-cell response to prevent liver fibrosis in patients with chronic hepatitis B. ( Jia, M; Jiang, W; Li, J; Li, L; Liu, Y; She, W; Wang, J, 2015)
"Entecavir (ETV) is effective in the treatment of chronic hepatitis B virus (HBV) infections, even in patients with underlying cirrhosis."3.81Efficacy of telbivudine compared with entecavir in hepatitis B virus-related cirrhosis: 2 year follow-up data. ( Byun, KS; Hyun, JJ; Kang, S; Kim, HR; Kim, JH; Kim, SY; Koo, JS; Lee, SW; Seo, YS; Suh, SJ; Um, SH; Yeon, JE; Yim, HJ, 2015)
"This study was aimed to evaluate the long-term effects of telbivudine (LdT) in the treatment of chronic hepatitis B (CHB) and HBV-related liver cirrhosis (LC) and to observe the changes of immunological responses during LdT treatment."3.81Efficacy of telbivudine in the treatment of chronic hepatitis b and liver cirrhosis and its effect on immunological responses. ( Gao, X; Liu, P; Lu, XD; Lu, YQ; Meng, N; Tang, WX; Wang, M; Yan, W; Zhang, SJ, 2015)
" To examine changes in phosphorylated Smad3 signalling before and after anti-HBV therapies, we chose 27 patients with chronic hepatitis B who underwent baseline and follow-up biopsies at 52 weeks from the start of nucleoside analogue treatments (Lamivudine 100 mg daily or Telbivudine 600 mg daily)."3.80Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection. ( Deng, YR; Jin, QL; Lian, ZX; Matsuzaki, K; Moritoki, Y; Murata, M; Niu, JQ; Tsuneyama, K; Yamaguchi, T; Yoshida, K, 2014)
"Data are limited for comparison of the long-term efficacy of telbivudine (LdT) between hepatitis B virus (HBV)-related compensated and decompensated cirrhosis."3.80Comparison of telbivudine efficacy in treatment-naive patients with hepatitis B virus-related compensated and decompensated cirrhosis in 96 weeks. ( Li, J; Liu, J; Lu, W; Wang, J; Yang, X; Zhou, L, 2014)
"Since the licensing of lamivudine in 1999, the treatment of chronic hepatitis B has been revolutionized by the introduction of oral nucleoside and nucleotide analogues (NAs), which act as inhibitors of the HBV polymerase."3.80Antiviral therapy of chronic hepatitis B. ( Berg, T; van Bömmel, F, 2014)
"The aim of this study was to evaluate the efficacy and safety of telbivudine 600 mg/day compared with lamivudine 100 mg/day for 48 weeks of treatment in patients with hepatitis B-related cirrhosis."3.79Forty-eight-week retrospective study of telbivudine and lamivudine treatment in patients with hepatitis B-related cirrhosis. ( Chen, Y; Gao, Z; Han, Y; Han, Z; Jia, G; Li, C; Liu, J; Luo, G; Shi, Y; Xia, L; Yin, F; Zhou, X; Zhu, J, 2013)
"The structure of the duodenum mucosa and proliferation of the epithelium were studied in 138 patients with chronic hepatitis and cirrhosis of the liver by count of the number of mitoses and that of cells labeled in the phase of DNA synthesis with 3H-thymidine."3.65[Proliferative properties of the epithelium of the duodenal mucosa in chronic hepatitis and liver cirrhosis]. ( Gerlovich, ESh; Iakhontova, OI; Kazaev, IS; Puzyrev, AA; Shul'man, VSh, 1977)
"Telbivudine treatment was an independent predictive factor for HBV DNA <300 copies/mL and ALT normalization (P = 0."2.77Randomized clinical trial: efficacy and safety of telbivudine and lamivudine in treatment-naïve patients with HBV-related decompensated cirrhosis. ( Avila, C; Bao, W; Chan, HL; Chen, YC; Choudhuri, G; Chutaputti, A; Gane, EJ; Hwang, SG; Piratvisuth, T; Prabhakar, B; Safadi, R; Sarin, SK; Suh, DJ; Tanwandee, T; Trylesinski, A; Yurdaydin, C, 2012)
"Hepatitis B is a major cause of hepatocellular carcinoma and liver cirrhosis."2.52Hepatitis B: encouraging the use of interferon. ( Krishnamoorthy, TL; Mutimer, D, 2015)
"Mortality and complications including hepatocellular carcinoma are associated primarily with cirrhosis and age, but not with HBeAg status or viral load probably because modern therapies considerably reduce viral replication in almost all patients."1.43Long-term follow-up of HBsAg-positive patients in Germany. ( Amani, A; Niederau, C; Thiel, A, 2016)
"Chronic hepatitis B affects 5-10% of HIV patients in Western countries."1.35Hepatitis B in HIV patients: what is the current treatment and what are the challenges? ( Barreiro, P; Fernández, JV; Labarga, P; Medrano, J; Soriano, V; Tuma, P; Vispo, E, 2009)
"In the present series of hepatocellular carcinoma patients, the 3-year clinical outcome was significantly affected by cell proliferation and ECM-associated antigens."1.29Biological markers in hepatocellular carcinoma: potential clinical implications. ( Costa, A; D'Errico, A; Faranda, A; Gennari, L; Grigioni, W; Regalia, E; Silvestrini, R, 1993)

Research

Studies (66)

TimeframeStudies, this research(%)All Research%
pre-199027 (40.91)18.7374
1990's2 (3.03)18.2507
2000's10 (15.15)29.6817
2010's27 (40.91)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liang, X1
Xie, Q2
Tan, D2
Ning, Q1
Niu, J2
Bai, X1
Chen, S1
Cheng, J1
Yu, Y2
Wang, H1
Xu, M1
Shi, G2
Wan, M2
Chen, X1
Tang, H1
Sheng, J1
Dou, X1
Shi, J1
Ren, H2
Wang, M2
Zhang, H1
Gao, Z2
Chen, C2
Ma, H1
Chen, Y2
Fan, R1
Sun, J1
Jia, J2
Hou, J1
Liu, J3
Yao, N1
Zhao, Y1
Han, Z1
Shi, Y1
Zhu, J1
Yin, F1
Xia, L1
Luo, G1
Jia, G1
Li, C1
Zhou, X1
Han, Y1
Tian, Y1
Ni, D1
Yang, W1
Zhang, Y1
Zhao, K1
Song, J1
Mao, Q1
Tian, Z1
van Velkinburgh, JC1
Yang, D1
Wu, Y1
Ni, B1
Park, YH1
Kim, BK1
Kim, JK1
Kim, HC1
Kim, DY1
Park, JY1
Han, KH1
Kim, SU1
Shin, SH1
Hahn, KY1
Ahn, SH1
Deng, YR1
Yoshida, K2
Jin, QL1
Murata, M2
Yamaguchi, T1
Tsuneyama, K1
Moritoki, Y1
Niu, JQ1
Matsuzaki, K2
Lian, ZX1
Calvaruso, V1
Craxì, A1
Yang, X1
Li, J2
Zhou, L1
Wang, J3
Lu, W1
Tsai, MC2
Yu, HC1
Hung, CH2
Lee, CM2
Chiu, KW1
Lin, MT1
Tseng, PL1
Chang, KC1
Yen, YH1
Chen, CH2
Hu, TH2
Jia, M1
Liu, Y2
She, W1
Li, L1
Jiang, W2
Kim, HR1
Yim, HJ1
Kang, S1
Suh, SJ1
Kim, SY1
Hyun, JJ1
Koo, JS1
Kim, JH1
Seo, YS1
Yeon, JE1
Lee, SW1
Byun, KS1
Um, SH1
van Bömmel, F1
Berg, T1
Coffin, CS1
Rezaeeaval, M1
Pang, JX1
Alcantara, L1
Klein, P1
Burak, KW1
Myers, RP1
Cholongitas, E1
Vasiliadis, T1
Goulis, I1
Fouzas, I1
Antoniadis, N1
Papanikolaou, V1
Akriviadis, E1
Meng, N1
Gao, X1
Yan, W1
Liu, P1
Lu, XD1
Zhang, SJ1
Lu, YQ1
Tang, WX1
Hou, JL2
Xu, D1
Goodman, Z1
Wei, L1
Wang, Q1
Wang, Y1
Bao, W2
Dong, Y1
Trylesinski, A2
Naoumov, NV1
Krishnamoorthy, TL1
Mutimer, D1
Niederau, C2
Amani, A1
Thiel, A1
Wang, GL1
Qiu, P1
Zhou, SF1
Xu, LF1
Wen, P1
Wen, JB1
Xiao, XZ1
Yue-Meng, W1
Li, YH1
Wu, HM1
Yang, J1
Xu, Y1
Yang, LH1
Yang, JH1
Lu, SN1
Wang, JH1
Shen, H1
Ding, F1
Wang, Z1
Sun, F1
Zhou, J1
Xu, W1
Ni, J1
Yang, Y1
Chien, RN1
Liaw, YF1
Liang, J1
Han, T1
Xiao, SX1
Chen, W1
Soriano, V1
Tuma, P1
Vispo, E1
Labarga, P1
Fernández, JV1
Medrano, J1
Barreiro, P1
Gou, YZ1
Liu, B1
Yu, HT1
Bai, XF1
Cho, YK1
Song, BC1
Singal, AK1
Fontana, RJ1
Chan, HL1
Chen, YC1
Gane, EJ1
Sarin, SK1
Suh, DJ1
Piratvisuth, T1
Prabhakar, B1
Hwang, SG1
Choudhuri, G1
Safadi, R1
Tanwandee, T1
Chutaputti, A1
Yurdaydin, C1
Avila, C1
Huang, Y1
Wu, H1
Wu, S1
Fu, D1
Ma, Y1
Shen, X1
MACDONALD, RA3
MALLORY, GK2
LEEVY, CM3
TENHOVE, W1
HOWARD, M1
RAMALINGASWAMI, V1
SCHMID, R1
Hrckova, G1
Velebný, S1
Daxnerová, Z1
Solár, P1
Sekimoto, G1
Uemura, Y1
Sakaida, N1
Kaibori, M1
Kamiyama, Y1
Nishizawa, M1
Fujisawa, J1
Okazaki, K1
Seki, T1
Ayoub, WS1
Keeffe, EB1
Winter, GC1
McCarthy, CF1
Read, AE1
Yoffey, JM1
Gimferrer, E1
Guarner, C1
Balanzó, J1
Ayats, R1
Fábrega, J1
Baiget, M1
Pujol, N1
Presa, F1
Simón, X1
Altés, R1
Silvestrini, R1
Costa, A1
D'Errico, A1
Faranda, A1
Regalia, E1
Grigioni, W1
Gennari, L1
Wang, JY1
Zhang, QS1
Guo, JS1
Hu, MY1
Zolotnitskaia, RP1
Sorokin, AV1
Boss, JH1
Okon, E1
Rosenmann, E1
Barinsky, IF1
Dementiev, IV1
Shvetsova, TP1
Ugryumov, EP1
Ryabova, MV1
Bugbee, SJ1
Sutnick, AI1
Millman, I1
Blumberg, BS1
Gerlovich, ESh1
Iakhontova, OI1
Puzyrev, AA1
Shul'man, VSh1
Kazaev, IS1
Griffith, DP1
Musher, DM1
Lanfrancone, L1
Boraschi, D1
Ghiara, P1
Falini, B1
Grignani, F1
Peri, G1
Mantovani, A1
Pelicci, PG1
Tsuji, T1
Nozaki, H1
Naito, K1
Kosaka, K1
Pappas, A1
Phlippen, R1
Pütz, T1
Scheurlen, PG1
Mohr, U1
Speetzen, R1
Knecht, M1
Wrba, H1
Maerker-Alzer, G1
Schumacher, K1
Gross, R1
Berenyi, MR1
Straus, B1
Cruz, D1
Sorrell, MF1
Scheiffarth, F1
Warnatz, H1
Ottenjann, R1
Ritter, H1
Stöcker, E1
Heine, WD1
Surianu, P1
Heiniger, HJ1
Feinendegen, LE1
Okura, T1
Rubin, E1
Hutterer, F1
Popper, H1
Newberne, PM1
Rogers, AE1
Bailey, C1
Young, VR1
Shea, SM2
Bartholomay, AF1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Single Arm, Multicenter, Open-label, 52-week, the Omnibus Extension Study to Evaluate the Safety and Efficacy of Telbivudine in the Fifth Year of Treatment in Chinese Patients With Compensated Chronic Hepatitis B and Are HBV DNA PCR Negative at the End [NCT00646503]Phase 4150 participants (Actual)Interventional2008-03-31Completed
A Single-arm, Multicenter, Open-label, 52-week Treatment, Extension Study to CLDT600ACN04 Study to Evaluate the Efficacy (Including Histological Improvement) and Safety in Fourth to Sixth Year of Telbivudine Treatment in Patients With Chronic Hepatitis B[NCT00877149]Phase 480 participants (Anticipated)Interventional2009-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

7 reviews available for thymidine and Liver Cirrhosis

ArticleYear
Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible?
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1

    Topics: Adenine; Administration, Oral; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Guanine; Hepat

2014
Hepatitis B: encouraging the use of interferon.
    Current opinion in infectious diseases, 2015, Volume: 28, Issue:6

    Topics: Adjuvants, Immunologic; Antiviral Agents; Carcinoma, Hepatocellular; Contraindications; Drug Adminis

2015
Nucleos(t)ide analogues for hepatitis B virus: strategies for long-term success.
    Best practice & research. Clinical gastroenterology, 2008, Volume: 22, Issue:6

    Topics: Adenine; Adenine Nucleotides; Alanine Transaminase; Carcinoma, Hepatocellular; DNA, Viral; Drug Admi

2008
Meta-analysis: oral anti-viral agents in adults with decompensated hepatitis B virus cirrhosis.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:6

    Topics: Adenine; Administration, Oral; Adult; Antiviral Agents; Drug Resistance, Viral; Drug Therapy, Combin

2012
A meta-analysis of nucleos(t)ide analogues in patients with decompensated cirrhosis due to hepatitis B.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:3

    Topics: Antiviral Agents; Hepatitis B; Humans; Lamivudine; Liver Cirrhosis; Nucleosides; Nucleotides; Revers

2013
Review article: current antiviral therapy of chronic hepatitis B.
    Alimentary pharmacology & therapeutics, 2008, Volume: 28, Issue:2

    Topics: Adenine; Antiviral Agents; Carcinoma, Hepatocellular; Deoxycytidine; Drug Resistance, Viral; Emtrici

2008
[Lymphocyte transformation in liver diseases (review of the literature)].
    Laboratornoe delo, 1975, Issue:2

    Topics: Antigens; Chronic Disease; Glucocorticoids; Hepatitis; Humans; Liver; Liver Cirrhosis; Liver Disease

1975

Trials

8 trials available for thymidine and Liver Cirrhosis

ArticleYear
Interpretation of liver stiffness measurement-based approach for the monitoring of hepatitis B patients with antiviral therapy: A 2-year prospective study.
    Journal of viral hepatitis, 2018, Volume: 25, Issue:3

    Topics: Adolescent; Adult; Alanine Transaminase; Antiviral Agents; Biopsy; Drug Monitoring; Drug Therapy, Co

2018
Comparing the efficacy and clinical outcome of telbivudine and entecavir naïve patients with hepatitis B virus-related compensated cirrhosis.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:3

    Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Disease Progression; DNA, Viral; Female; Guanin

2014
Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B.
    Advances in therapy, 2015, Volume: 32, Issue:8

    Topics: Adult; Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hu

2015
Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B.
    Advances in therapy, 2015, Volume: 32, Issue:8

    Topics: Adult; Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hu

2015
Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B.
    Advances in therapy, 2015, Volume: 32, Issue:8

    Topics: Adult; Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hu

2015
Long-Term Telbivudine Treatment Results in Resolution of Liver Inflammation and Fibrosis in Patients with Chronic Hepatitis B.
    Advances in therapy, 2015, Volume: 32, Issue:8

    Topics: Adult; Antiviral Agents; Female; Hepatitis B e Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hu

2015
Cost-effectiveness of Lamivudine, Telbivudine, Adefovir Dipivoxil and Entecavir on decompensated hepatitis B virus-related cirrhosis.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:5

    Topics: Adenine; Adult; Antiviral Agents; Cost-Benefit Analysis; Female; Guanine; Hepatitis B virus; Hepatit

2016
Comparison of Telbivudine and Entecavir Therapy on Nephritic Function and Drug Resistance in Patients with Hepatitis B Virus-Related Compensated Cirrhosis.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2016, Volume: 40, Issue:1-2

    Topics: Creatinine; DNA, Viral; Drug Resistance, Viral; Female; Glomerular Filtration Rate; Guanine; Hepatit

2016
[Telbivudine treatment on cirrhosis resulting from chronic hepatitis B].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:1

    Topics: Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Female; Hepatitis B e Antigens; Hepatit

2009
The diagnostic value of ultrasound elastography in patients with hepatitis B virus infection: a prospective study.
    The Journal of international medical research, 2010, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; Asian People; China; Demography; El

2010
Randomized clinical trial: efficacy and safety of telbivudine and lamivudine in treatment-naïve patients with HBV-related decompensated cirrhosis.
    Journal of viral hepatitis, 2012, Volume: 19, Issue:10

    Topics: Adolescent; Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Double-Blind Method; Fe

2012

Other Studies

51 other studies available for thymidine and Liver Cirrhosis

ArticleYear
Improvement of telbivudine on renal function and massive proteinuria: A case report.
    Journal of viral hepatitis, 2017, Volume: 24 Suppl 1

    Topics: Antiviral Agents; Biomarkers; Hepatitis B, Chronic; Humans; Kidney Function Tests; Liver Cirrhosis;

2017
Forty-eight-week retrospective study of telbivudine and lamivudine treatment in patients with hepatitis B-related cirrhosis.
    Journal of viral hepatitis, 2013, Volume: 20 Suppl 1

    Topics: Adolescent; Adult; Aged; Antiviral Agents; DNA, Viral; Female; Hepatitis B; Hepatitis B e Antigens;

2013
Telbivudine treatment corrects HBV-induced epigenetic alterations in liver cells of patients with chronic hepatitis B.
    Carcinogenesis, 2014, Volume: 35, Issue:1

    Topics: Antiviral Agents; Case-Control Studies; Chromatin; Enhancer of Zeste Homolog 2 Protein; Epigenesis,

2014
Long-term outcomes of chronic hepatitis B virus infection in the era of antiviral therapy in Korea.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Female; Follow

2014
Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection.
    Clinical and experimental immunology, 2014, Volume: 176, Issue:1

    Topics: Adult; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; DNA, Viral; Female; Hepatit

2014
Comparison of telbivudine efficacy in treatment-naive patients with hepatitis B virus-related compensated and decompensated cirrhosis in 96 weeks.
    European journal of gastroenterology & hepatology, 2014, Volume: 26, Issue:4

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; Cholinesterases; Drug Resistance, Viral;

2014
Telbivudine therapy may shape CD4(+) T-cell response to prevent liver fibrosis in patients with chronic hepatitis B.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Antiviral Agents; Case-Control Studies; CD4-Positive T-Lymphocytes; Cells, Cultur

2015
Efficacy of telbivudine compared with entecavir in hepatitis B virus-related cirrhosis: 2 year follow-up data.
    Liver international : official journal of the International Association for the Study of the Liver, 2015, Volume: 35, Issue:3

    Topics: Adult; Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Drug-Related Side Effects and Adverse R

2015
Antiviral therapy of chronic hepatitis B.
    Intervirology, 2014, Volume: 57, Issue:3-4

    Topics: Adenine; Antiviral Agents; Arabinofuranosyluracil; Carcinoma, Hepatocellular; Gene Products, pol; Gu

2014
The incidence of hepatocellular carcinoma is reduced in patients with chronic hepatitis B on long-term nucleos(t)ide analogue therapy.
    Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:11-12

    Topics: Adenine; Adult; Antiviral Agents; Canada; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B e

2014
Telbivudine is associated with improvement of renal function in patients transplanted for HBV liver disease.
    Journal of viral hepatitis, 2015, Volume: 22, Issue:7

    Topics: Adult; Aged; Antiviral Agents; Chemoprevention; DNA, Viral; Female; Glomerular Filtration Rate; Hepa

2015
Efficacy of telbivudine in the treatment of chronic hepatitis b and liver cirrhosis and its effect on immunological responses.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2015, Volume: 35, Issue:2

    Topics: Adult; Aged; Antiviral Agents; Female; Hepatitis B, Chronic; Humans; Liver Cirrhosis; Male; Middle A

2015
Long-term follow-up of HBsAg-positive patients in Germany.
    European journal of gastroenterology & hepatology, 2016, Volume: 28, Issue:1

    Topics: Adenine; Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Drug Therapy,

2016
Telbivudine versus lamivudine and entecavir for treatment-naïve decompensated hepatitis B virus-related cirrhosis.
    Clinical and experimental medicine, 2017, Volume: 17, Issue:2

    Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; DNA, Viral; Drug-Related Side Effects and Adver

2017
Long-term outcomes of hepatitis B virus-related cirrhosis treated with nucleos(t)ide analogs.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2017, Volume: 116, Issue:7

    Topics: Adult; Aged; Antiviral Agents; Carcinoma, Hepatocellular; Female; Guanine; Hepatitis B, Chronic; Hum

2017
[Pharmacoeconomic evaluation of telbivudine vs. lamivudine in treating the patients with HBeAg-positive and negative chronic hepatitis B].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2009, Volume: 17, Issue:8

    Topics: Adult; Antifungal Agents; China; Cost-Benefit Analysis; DNA, Viral; Drug Costs; Economics, Pharmaceu

2009
Hepatitis B in HIV patients: what is the current treatment and what are the challenges?
    Journal of HIV therapy, 2009, Volume: 14, Issue:1

    Topics: Adenine; Antiviral Agents; Deoxycytidine; DNA, Viral; Drug Therapy, Combination; Emtricitabine; Guan

2009
[New insight for HBV DNA and HBsAg quantitation during antiviral therapy in patients with chronic hepatitis B].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2011, Volume: 57, Issue:3

    Topics: Antiviral Agents; Carcinoma, Hepatocellular; DNA, Viral; Hepatitis B Surface Antigens; Hepatitis B v

2011
Fibrous tissue in nutritional cirrhosis; autoradiographic studies with use of tritiated thymidine.
    A.M.A. archives of pathology, 1959, Volume: 67, Issue:2

    Topics: Autoradiography; Humans; Liver Cirrhosis; Lymphatic Vessels; Thymidine

1959
"Lifespan" of liver cells. Autoradio-graphic study using tritiated thymidine in normal, cirrhotic, and partially hepatectomized rats.
    Archives of internal medicine, 1961, Volume: 107

    Topics: Animals; Liver; Liver Cirrhosis; Nucleosides; Nucleotides; Rats; Thymidine

1961
MESENCHYMAL-CELL PROLIFERATION IN LIVER DISEASE OF THE ALCOHOLIC.
    JAMA, 1964, Feb-22, Volume: 187

    Topics: Alcoholism; Autoradiography; Cell Proliferation; DNA; Ethanol; Fatty Liver; Liver; Liver Cirrhosis;

1964
PERSPECTIVES IN PROTEIN MALNUTRITION.
    Nature, 1964, Feb-08, Volume: 201

    Topics: Animals; Fatty Liver; Haplorhini; Jejunum; Kwashiorkor; Liver Cirrhosis; Pancreas; Pathology; Protei

1964
HEPATIC DNA SYNTHESIS AND REGENERATION.
    Biochemical clinics, 1964, Volume: 3

    Topics: Adrenal Cortex Hormones; Anabolic Agents; Autoradiography; Biopsy; Diet; Diet Therapy; DNA; Drug The

1964
Regeneration in fatty liver and cirrhosis: autoradiographic study using tritiated thymidine.
    Archives of pathology, 1960, Volume: 69

    Topics: Animals; Fatty Liver; Liver Cirrhosis; Liver Cirrhosis, Experimental; Liver Diseases; Nucleosides; N

1960
Praziquantel and liposomized glucan-treatment modulated liver fibrogenesis and mastocytosis in mice infected with Mesocestoides vogae (M. corti, Cestoda) tetrathyridia.
    Parasitology, 2006, Volume: 132, Issue:Pt 4

    Topics: Animals; Anthelmintics; beta-Glucans; Bromodeoxyuridine; Cestode Infections; Collagen; Drug Therapy,

2006
Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:1

    Topics: alpha-Fetoproteins; Biopsy; Carcinoma, Hepatocellular; Disease Progression; DNA Replication; Hepatit

2007
[Treatment in every detected virus replication. New guideline for therapy of hepatitis B publicized].
    MMW Fortschritte der Medizin, 2007, Jul-19, Volume: 149, Issue:29-30

    Topics: Antiviral Agents; DNA, Viral; Drug Resistance, Viral; Hepatitis B virus; Hepatitis B, Chronic; Human

2007
[New German and American guidelines for therapy of hepatitis B. Discrepancies and similarities].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Sep-15, Volume: 102, Issue:9

    Topics: Adenine; Alanine Transaminase; Antiviral Agents; Biopsy; DNA, Viral; Drug Resistance, Viral; Drug Th

2007
Development of macrophages in phytohaemagglutinin cultures of blood from patients with idiopathic steatorrhoea and with cirrhosis.
    British journal of experimental pathology, 1967, Volume: 48, Issue:1

    Topics: Adolescent; Adult; Aged; Autoradiography; Celiac Disease; Culture Media; DNA; Female; Hemagglutinati

1967
[Macrocytosis in the liver patient: study of blood folate and vitamin B 12, and thymidine synthesis in hematopoietic cells].
    Sangre, 1982, Volume: 27, Issue:4-B

    Topics: Adult; Anemia, Macrocytic; Anemia, Megaloblastic; Female; Folic Acid; Hematopoietic Stem Cells; Huma

1982
Biological markers in hepatocellular carcinoma: potential clinical implications.
    Journal of surgical oncology. Supplement, 1993, Volume: 3

    Topics: Antigens, Neoplasm; Biomarkers; Carcinoma, Hepatocellular; Cell Cycle; Cell Division; Collagenases;

1993
Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats.
    World journal of gastroenterology, 2001, Volume: 7, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Cell Division; Col

2001
alpha-fetoprotein in rats treated with anti-thymocytic serum.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:4

    Topics: alpha-Fetoproteins; Animals; Antilymphocyte Serum; Diet; Female; Glomerulonephritis; Liver; Liver Ci

1977
Investigation of the nature of Australia antigen. I: The absence of biological activity of Australia antigen in human blood leukocyte culture.
    Archives of virology, 1975, Volume: 47, Issue:3

    Topics: Adolescent; Adult; Chromosome Aberrations; DNA Nucleotidyltransferases; Down Syndrome; Female; Hepat

1975
[Proliferative properties of the epithelium of the duodenal mucosa in chronic hepatitis and liver cirrhosis].
    Arkhiv patologii, 1977, Volume: 39, Issue:1

    Topics: Adult; Autoradiography; Cell Count; Cell Division; Chronic Disease; DNA; Duodenum; Epithelium; Hepat

1977
Acetohydroxamic acid. Potential use in urinary infection caused by urea-splitting bacteria.
    Urology, 1975, Volume: 05, Issue:3

    Topics: Acetamides; Administration, Oral; Animals; Bacteria; Binding Sites; Chemical Phenomena; Chemistry; D

1975
Human peritoneal mesothelial cells produce many cytokines (granulocyte colony-stimulating factor [CSF], granulocyte-monocyte-CSF, macrophage-CSF, interleukin-1 [IL-1], and IL-6) and are activated and stimulated to grow by IL-1.
    Blood, 1992, Dec-01, Volume: 80, Issue:11

    Topics: Antigens, CD; Blotting, Northern; Cell Division; Cells, Cultured; Cytokines; DNA; Epithelium; Granul

1992
Blast-like transformation of lymphocyte stimulated with Australia antigen--brief note.
    Acta medicinae Okayama, 1972, Volume: 26, Issue:1

    Topics: Abdomen; Adult; Aged; Autoradiography; Chronic Disease; Female; Hepatitis; Hepatitis B Antigens; Hum

1972
[Disturbance of the cellular immunoreaction at the initial stage of acute infectious hepatitis].
    Klinische Wochenschrift, 1970, Nov-15, Volume: 48, Issue:22

    Topics: Carbon Isotopes; Cell Count; Culture Techniques; DNA, Bacterial; Hepatitis A; Hepatovirus; Humans; H

1970
[Regeneration, following partial hepatectomy, of liver chronically damaged by diethylnitrosamine].
    Zeitschrift fur Naturforschung. Teil B, Chemie, Biochemie, Biophysik, Biologie und verwandte Gebiete, 1968, Volume: 23, Issue:4

    Topics: Animals; Autoradiography; DNA; Female; Hepatectomy; Liver; Liver Cirrhosis; Liver Regeneration; Nitr

1968
Detection of lymphocytes with increased DNA-synthesis in the peripheral blood of patients with active chronic hepatitis.
    Klinische Wochenschrift, 1974, Feb-15, Volume: 52, Issue:4

    Topics: Antibodies; Antibodies, Antinuclear; Blood Donors; Chronic Disease; DNA; Hepatitis; Hepatitis B Anti

1974
In vitro and in vivo studies of cellular immunity in alcoholic cirrhosis.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:3

    Topics: Alcoholism; Candida albicans; Carbon Radioisotopes; Chlorine; Croton Oil; Humans; Hypersensitivity,

1974
Lymphocyte transformation and alcoholic liver injury.
    Gastroenterology, 1972, Volume: 63, Issue:6

    Topics: Acetaldehyde; Alcoholism; Cells, Cultured; Chemical and Drug Induced Liver Injury; DNA; Ethanol; Fat

1972
[Lymphocyte transformation in chronic hepatitis and other hepatic diseases].
    Archiv fur klinische Medizin, 1969, Volume: 216, Issue:5

    Topics: Antibodies; Autoradiography; Chronic Disease; Culture Techniques; Fatty Liver; Fluorescent Antibody

1969
Regeneration of liver parenchyma under normal and pathological conditions.
    Beitrage zur Pathologie, 1971, Volume: 144, Issue:4

    Topics: Acetamides; Age Factors; Animals; Autoradiography; Cell Division; Epithelium; Hepatectomy; Liver; Li

1971
[Diminished phytohemagglutinin stimulation of human lymphocyte cultures in liver cirrhosis: studies with 3H-thymidine and I-125 desoxyuridine].
    Blut, 1970, Volume: 20, Issue:6

    Topics: Culture Techniques; Deoxyuridine; DNA; Hepatitis; Humans; Iodine Radioisotopes; Lectins; Liver; Live

1970
Study on the pathogenesis of nephritis (with special reference to autoradiography). I. Experimental studies.
    Japanese circulation journal, 1970, Volume: 34, Issue:11

    Topics: Animals; Autoradiography; Carbon Tetrachloride Poisoning; DNA; Kidney Glomerulus; Kidney Tubules; Li

1970
Experimental hepatic fibrosis without hepatocellular regeneration. A kinetic study.
    The American journal of pathology, 1968, Volume: 52, Issue:1

    Topics: Animals; Antibodies, Heterophile; Autoradiography; Body Weight; Collagen; DNA; Humans; Immune Sera;

1968
The induction of liver cirrhosis in rats by purified amino acid diets.
    Cancer research, 1969, Volume: 29, Issue:1

    Topics: Amino Acids; Animals; Body Weight; Cholesterol; Choline Deficiency; Deficiency Diseases; Diet; Dieta

1969
In numero studies in a cell renewal system. Periodically adjusted cell renewal process.
    Journal of theoretical biology, 1965, Volume: 9, Issue:3

    Topics: Animals; Autoradiography; Carbon Tetrachloride; Computers; DNA; Kinetics; Liver Cirrhosis; Liver Cir

1965
Experimental toxic cirrhosis in the rat. Kinetics of hepatocyte proliferation during intermittent carbon tetrachloride intoxication.
    Experimental and molecular pathology, 1966, Volume: 5, Issue:3

    Topics: Animals; Autoradiography; Biometry; Carbon Tetrachloride Poisoning; Cell Division; Computers; Kineti

1966