thymidine has been researched along with Leukemia in 314 studies
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we report that the tea polyphenol (-)-epigallocatechin (EGC) inhibits DNA replication in three leukemia cancer cell lines, Jurkat T, HL-60 and K562." | 7.71 | Green tea polyphenol epigallocatechin inhibits DNA replication and consequently induces leukemia cell apoptosis. ( Dou, QP; Smith, DM, 2001) |
| "Twenty-seven patients with acute leukemia have been treated by sequential 6-day courses of thymidine (30 g/m2 by i." | 7.67 | Modulation of 1-beta-D-arabinofuranosylcytosine metabolism by thymidine in human acute leukemia. ( Creaven, P; Marquet, J; Rustum, Y; Zittoun, J; Zittoun, R, 1985) |
| "We have carried out a clinical trial in which patients with relapsed leukemia were treated with thymidine (dThd) prior to and concomitantly with the administration of 1-beta-D-arabinofuranosylcytosine (ara-C) in an effort to kinetically and biochemically modulate the leukemic cells with two objectives: (a) to increase the S-phase fraction before giving ara-C; and (b) to increase the uptake and phosphorylation of ara-C." | 7.67 | Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia. ( Andreeff, M; Blumenreich, MS; Chou, TC; Clarkson, BD; Vale, K; Young, CW, 1984) |
| " Bone marrow cells from patients with acute nonlymphocytic leukemia (ANLL) were studied by both the RPMB technique and tritiated thymidine (3HdThd) labeling index studies." | 7.67 | Double labeling and in vitro versus in vivo incorporation of bromodeoxyuridine in patients with acute nonlymphocytic leukemia. ( Preisler, HD; Raza, A; Ucar, K, 1985) |
| "Normal marrow granulocyte (CFU-GM) and peripheral blood T-lymphocyte (CFU-TL) colony-forming cells were studied for their sensitivity to high concentrations of thymidine (dThd) and compared to leukemic CFU from patients with acute nonlymphocytic leukemia (ANLL)." | 7.66 | Thymidine as a chemotherapeutic agent: sensitivity of normal human marrow, peripheral blood T cells, and acute nonlymphocytic leukemia. ( Howell, SB; Mendelsohn, J; Taetle, R, 1980) |
| "Patients with acute leukemia were given repeated cycles consisting of infusions of methotrexate followed by "rescue" with folinic acid." | 7.65 | Treatment of leukemia with large doses of methotrexate and folinic acid: clinical-biochemical correlates. ( Bertino, JR; Hryniuk, WM, 1969) |
| " The killing of cells and apparent beneficial effect of tritiated thymidine in human leukemia are described." | 4.76 | Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia? ( Cronkite, EP; Fairchild, RG; Miller, ME, 1983) |
| " In the present study, two PPAR-gamma agonists, 15-deoxy-delta (12,14)-prostaglandin J2 (15d-PGJ2) and a synthetic PPAR-gamma agonist troglitazone (TGZ), were used to investigate activated PPAR-gamma-induced apoptosis on human monocyte leukemia U937 and Mono Mac 6 cells in vitro." | 3.74 | Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro. ( He, Y; Huang, M; Huang, RW; Li, XD; Lin, DJ; Liu, JJ; Liu, PQ; Xiao, RZ, 2007) |
| "This study found that oridonin, a natural diterpenoid purified from Rabdosia rubescens, inhibited growth of multiple myeloma (MM; U266, RPMI8226), acute lymphoblastic T-cell leukemia (Jurkat), and adult T-cell leukemia (MT-1) cells with an effective dose that inhibited 50% of target cells (ED50) ranging from 0." | 3.73 | Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways. ( Bandobashi, K; Ikezoe, T; Koeffler, HP; Machida, H; Saito, T; Taguchi, H; Takemoto, S; Togitani, K; Yang, Y, 2005) |
| " Here, we describe thymineless death of human myeloid leukemia U937 cells treated with the thymidylate-synthase inhibitor 5'-fluoro- 2'-deoxyuridine (FUdR)." | 3.72 | Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells. ( López-Rivas, A; Muñoz-Pinedo, C; Robledo, G, 2004) |
| " Here we report that the tea polyphenol (-)-epigallocatechin (EGC) inhibits DNA replication in three leukemia cancer cell lines, Jurkat T, HL-60 and K562." | 3.71 | Green tea polyphenol epigallocatechin inhibits DNA replication and consequently induces leukemia cell apoptosis. ( Dou, QP; Smith, DM, 2001) |
| "Effects of lipophilic thymidylate synthase (TS) inhibitor AG337 on human head and neck squamous cell carcinoma (HNSCC) cell lines and CCRF-CEM human leukemia cells and sublines with acquired methotrexate (MTX) resistance were assayed using continuous or intermittent drug exposure." | 3.70 | Characterization of the effect of AG337, a novel lipophilic thymidylate synthase inhibitor, on human head and neck and human leukemia cell lines. ( Canestrari, JG; McGuire, JJ; Nagel, GS, 1999) |
| "PHA-stimulated human lymphocytes or myelogenous leukemia cells (strain K-562) were pulse labeled with 3H-thymidine and submitted to various fixation-permeabilization procedures." | 3.69 | PCNA immunopositivity index as a substitute to 3H-thymidine pulse-labeling index (TLI) in methanol-fixed human lymphocytes. ( Capel, P; Degraef, C; Del Bino, G; Feremans, W; Fokan, D; Galand, P; Morret, M, 1995) |
| "We evaluated the in vitro proliferative response to exogenous IL-1 beta in terms of tritiated thymidine (3H-TdR) incorporation in leukemic cells obtained from 119 patients with various types of acute leukemia." | 3.69 | Interleukin-1 beta (IL-1 beta) and acute leukemia: in vitro proliferative response to IL-1 beta, IL-1 beta content of leukemic cells and treatment outcome. ( Ezaki, K; Katsuta, I; Kojima, H; Maruyama, F; Miyazaki, H; Nomura, T; Okamoto, M; Sobue, R; Tsuzuki, M; Wakita, M, 1995) |
| " A survey of the in vitro activity of racemic 1-octadecyl-2-methoxy-glycero-3 phosphorylcholine on in vitro clonogenicity in soft agar and tritiated thymidine incorporation was conducted on bone marrow specimens from a series of patients with acute myelogenous leukemia (AML) and chronic myelocytic leukemia (CML) and hematologically normal individuals." | 3.67 | The effect of alkyl-lysophospholipids on tritiated thymidine incorporation and clonogenicity in vitro of normal and leukemic human cells. ( Long, RC; Somberg, LB; Vogler, WR; Whigham, EA; Winton, EF, 1984) |
| "We have carried out a clinical trial in which patients with relapsed leukemia were treated with thymidine (dThd) prior to and concomitantly with the administration of 1-beta-D-arabinofuranosylcytosine (ara-C) in an effort to kinetically and biochemically modulate the leukemic cells with two objectives: (a) to increase the S-phase fraction before giving ara-C; and (b) to increase the uptake and phosphorylation of ara-C." | 3.67 | Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia. ( Andreeff, M; Blumenreich, MS; Chou, TC; Clarkson, BD; Vale, K; Young, CW, 1984) |
| "Ara-C sensitivity test and suicide tests of L-CFU using [3H] deoxycytidine (dCyd) and [3H] thymidine (TdR) were performed in patients with acute nonlymphocytic leukemia (ANLL) and with chronic myeloid leukemia in blastic crisis (CML-BC)." | 3.67 | [Relationship between Ara-C sensitivity of leukemic-colony forming units (L-CFU) and [3H] deoxycytidine suicide test of L-CFU]. ( Shirai, T; Umeda, M, 1989) |
| "Ten patients with acute nonlymphocytic leukemia (ANLL) received bromodeoxyuridine (BrdU) at 100 mg/M2 intravenously over 1 h." | 3.67 | A new method for studying cell cycle characteristics in ANLL using double-labeling with BrdU and 3HTdr. ( Maheshwari, Y; Mandava, N; Mayers, G; Preisler, HD; Raza, A; Yasin, Z, 1987) |
| "440 and the ether-linked lipoidal amine CP-46,665 on tritiated thymidine uptake and trypan blue dye exclusion were tested in vitro in various freshly explanted cell samples from human nonneoplastic bone marrow and human leukemias." | 3.67 | Cytotoxic effects of ether lipids and derivatives in human nonneoplastic bone marrow cells and leukemic cells in vitro. ( Berdel, WE; Eibl, H; Fink, U; Fromm, M; Jehn, U; Rastetter, J; Reichert, A; Schick, HD; Ulm, K; Unger, C, 1987) |
| "Thioether lysophospholipid derivatives (TLP) inhibited the in vitro uptake of [3H]thymidine into blasts of eight leukemias and cells of 12 different solid tumors of human origin." | 3.67 | Antineoplastic activity of the thioether lysophospholipid derivative BM 41.440 in vitro. ( Berdel, WE; Bicker, U; Fink, U; Fromm, M; Pahlke, W; Rastetter, J; Reichert, A; Schick, HD, 1987) |
| "The toxicity and metabolism of a thymidine analogue, 5-hydroxymethyl-2'-deoxyuridine (5HmdUrd) were studied with human leukemia cells (HL-60) and with human platelets." | 3.67 | In vitro and in vivo studies of a promising antileukemic thymidine analogue, 5-hydroxymethyl-2' deoxyuridine. ( Bergstrom, D; Kahilainen, L; Kangas, L; Vilpo, JA, 1986) |
| "Cultured leukemic lymphocytes originating from patients with T, B and non-T, non-B (null) leukemia were tested for their sensitivity to thymidine and 5-fluorouracil." | 3.67 | The molecular basis for the differential sensitivity of B and T lymphocytes to growth inhibition by thymidine and 5-fluorouracil. ( el-Assouli, SM, 1985) |
| "Both established cell lines and human leukemic cells in circulating blood which were incubated in vitro with 2'-deoxyadenosine (AdR) plus adenosine deaminase inhibitor, 2'-deoxycoformycin (dCF), showed different metabolic responses depending upon the histologic and immunologic types of leukemia." | 3.67 | Differential sensitivity of leukemic cells to growth inhibition by deoxyadenosine and deoxycoformycin. ( Kimura, K; Tanaka, M, 1985) |
| " Bone marrow cells from patients with acute nonlymphocytic leukemia (ANLL) were studied by both the RPMB technique and tritiated thymidine (3HdThd) labeling index studies." | 3.67 | Double labeling and in vitro versus in vivo incorporation of bromodeoxyuridine in patients with acute nonlymphocytic leukemia. ( Preisler, HD; Raza, A; Ucar, K, 1985) |
| "The alkyl-linked lipoidal amine 4-aminomethyl-1-[2,3-(di-n-decyloxy)-n-propyl]-4-phenylpiperidine (CP-46,665) inhibited the in vitro incorporation of tritiated thymidine into blasts of eight leukemias and cells of nine different solid tumors of human origin." | 3.67 | Cytotoxicity of the alkyl-linked lipoidal amine 4-aminomethyl-1-[2,3-(di-n-decyloxy)-n-propyl]-4-phenylpiperidine (CP-46,665) in cells from human tumors and leukemias. ( Berdel, WE; Fink, U; Rastetter, J; Reichert, A; Schick, HD; Ulm, K, 1985) |
| "Twenty-seven patients with acute leukemia have been treated by sequential 6-day courses of thymidine (30 g/m2 by i." | 3.67 | Modulation of 1-beta-D-arabinofuranosylcytosine metabolism by thymidine in human acute leukemia. ( Creaven, P; Marquet, J; Rustum, Y; Zittoun, J; Zittoun, R, 1985) |
| " Bone marrow samples from 15 consecutive patients with acute nonlymphocytic leukemia (ANLL) were studied using an improved direct technique, amethopterin cell synchronization with thymidine release, and amethopterin cell synchronization with bromodeoxyuridine (BrdU) release." | 3.66 | Comparative analysis of high-resolution chromosome techniques for leukemic bone marrows. ( Yunis, JJ, 1982) |
| "Twenty-one patients with leukemia and lymphoma refractory to conventional therapy were treated with thymidine (dThd) at a dose of 75 g/m2/day for 48 h by continuous intravenous (IV) infusion, followed by cytosine arabinoside (ara-C) on an escalating dose schedule of 25-625 mg/m2/day for 48 h by continuous IV infusion." | 3.66 | A phase I-II study of combination therapy with thymidine and cytosine arabinoside. ( Beardsley, P; Egan, E; Fram, R; Kufe, D; Major, P; Rosenthal, D, 1983) |
| "Normal marrow granulocyte (CFU-GM) and peripheral blood T-lymphocyte (CFU-TL) colony-forming cells were studied for their sensitivity to high concentrations of thymidine (dThd) and compared to leukemic CFU from patients with acute nonlymphocytic leukemia (ANLL)." | 3.66 | Thymidine as a chemotherapeutic agent: sensitivity of normal human marrow, peripheral blood T cells, and acute nonlymphocytic leukemia. ( Howell, SB; Mendelsohn, J; Taetle, R, 1980) |
| " BMC and BMBC/cu mm BM were monitored in 16 patients with acute nonlymphoblastic leukemia treated with daunorubicin, cytosine arabinoside, and 6-thioguanine in combination and in 4 patients with end-stage acute leukemias and non-Hodgkin's lymphomas during high-dose thymidine therapy." | 3.66 | Bone marrow cell count per cubic millimeter bone marrow: a new parameter for quantitating therapy-induced cytoreduction in acute leukemia. ( Andreeff, M; Büchner, T; Clarkson, BD; Hiddemann, W; Melamed, MR, 1982) |
| "The prognostic value of the in vitro incorporation of labeled thymidine was evaluated in 53 cases of acute leukemia, by means of autoradiography and liquid scintillation (LS) count." | 3.65 | Prediction of the response to chemotherapy in acute leukemia. ( Bouchard, M; Bousser, J; Facquet-Danis, J; Percie-du-Sert, M; Zittoun, R, 1975) |
| "Patients with acute leukemia were given repeated cycles consisting of infusions of methotrexate followed by "rescue" with folinic acid." | 3.65 | Treatment of leukemia with large doses of methotrexate and folinic acid: clinical-biochemical correlates. ( Bertino, JR; Hryniuk, WM, 1969) |
| "3H-thymidine incorporation was measured after the addition of drug or vehicle to these confluent cells, and dose-response curves were generated." | 2.66 | An in vitro method which assesses corneal epithelial toxicity due to antineoplastic, preservative and antimicrobial agents. ( Botti, RE; Imperia, PS; Lass, JH; Lazarus, HM; Mack, RJ, 1989) |
| "The dose-response curves for the inhibition of equilibrative uridine transport by dilazep, dipyridamole and nitrobenzylthioinosine (NBMPR) in undifferentiated HL-60 cells were biphasic." | 1.29 | Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C. ( Lee, CW, 1994) |
| "Treatment with propranolol slightly enhanced the proliferation of the RC-2A cells but did not markedly alter the growth rate of two other cell lines, regardless of their beta-adrenoceptor status." | 1.28 | Expression and function of beta-adrenergic receptors in human hematopoietic cell lines. ( Andersson, LC; Kontula, KK; Mäki, T, 1992) |
| " All the mice given cells not treated with ALP succumbed to leukemia, whereas there was a dose-response increase in survival in those given ALP treated cells." | 1.28 | Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results. ( Berdel, WE; Glasser, L; Okamoto, S; Olson, AC; Vogler, WR, 1990) |
| "Thymidine incorporation was inhibited by the photodynamic effect depending on porphyrin concentration." | 1.28 | Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins. ( Ehrenberg, B; Faraggi, A; Malik, Z, 1989) |
| "Serum from cancer patients impaired the response of normal lymphocytes." | 1.25 | The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients. ( Kumar, S; Taylor, G, 1973) |
| "More precise definition of the cytokinetic parameters of human tumor growth will clearly help both in predicting the outcome of disease in individual patients and in planning the dosage schedules of single chemotherapeutic agents and combinations of agents to achieve optimal results." | 1.25 | Growth kinetics of solid tumors. Implications for chemotherapy. ( Curby, WA; Rosenoer, VM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 281 (89.49) | 18.7374 |
| 1990's | 23 (7.32) | 18.2507 |
| 2000's | 9 (2.87) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (0.32) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, YP | 1 |
| Sharda, A | 1 |
| Xu, SN | 1 |
| van Gastel, N | 1 |
| Man, CH | 1 |
| Choi, U | 1 |
| Leong, WZ | 1 |
| Li, X | 1 |
| Scadden, DT | 1 |
| Kalwak, K | 1 |
| Turkiewicz, D | 1 |
| Ussowicz, M | 1 |
| Gorczyńska, E | 1 |
| Toporski, J | 1 |
| Ryczan, R | 1 |
| Rybka, B | 1 |
| Noworolska-Sauren, D | 1 |
| Chybicka, A | 1 |
| GAVOSTO, F | 5 |
| PILERI, A | 5 |
| MARAINI, G | 1 |
| BIANCHI, PA | 2 |
| BOND, VP | 5 |
| RUBINI, JR | 4 |
| FLIEDNER, TM | 4 |
| CRONKITE, EP | 8 |
| GIGANTE, D | 1 |
| TEODORI, S | 1 |
| ZOPPINI, A | 1 |
| POLLI, E | 4 |
| BIANCHI, P | 2 |
| SALERA, U | 1 |
| KILLMANN, SA | 7 |
| ROBERTSON, JS | 1 |
| KUROYANAGI, T | 1 |
| SAITO, M | 1 |
| BENDICH, A | 1 |
| BORENFREUND, E | 1 |
| ITTENSOHN, OL | 1 |
| HUTCHISON, DJ | 1 |
| PEGORARO, L | 2 |
| MOMIGLIANO, A | 1 |
| VESELY, J | 3 |
| SCHMID, W | 1 |
| KANEKO, JJ | 1 |
| NAKAJIMA, H | 1 |
| SCHALM, OW | 1 |
| PERRY, S | 7 |
| MARSH, JC | 2 |
| DELAMORE, IW | 1 |
| PRUSOFF, WH | 1 |
| WINTER, GC | 1 |
| OSMOND, DG | 1 |
| YOFFEY, JM | 1 |
| MAHY, DJ | 1 |
| KELLER, S | 2 |
| MCCALL, MS | 1 |
| MAUER, AM | 5 |
| QUAGLINO, D | 1 |
| COWLING, DC | 1 |
| HAYHOE, FG | 1 |
| FARINA, MV | 2 |
| SILBER, R | 1 |
| COX, RP | 1 |
| HADDAD, JR | 1 |
| FRIEND, C | 2 |
| HALE, AJ | 1 |
| COOPER, EH | 5 |
| MILTON, JD | 2 |
| OTA, K | 2 |
| SCHUMACHER, HR | 3 |
| SALEN, G | 1 |
| LALA, PK | 1 |
| MALONEY, MA | 1 |
| PATT, HM | 1 |
| OPPENHEIM, JJ | 1 |
| WHANG, J | 1 |
| FREI, E | 2 |
| MATHIAS, AP | 1 |
| FISCHER, GA | 2 |
| POGO, BG | 1 |
| MOORE, AE | 1 |
| Muñoz-Pinedo, C | 1 |
| Robledo, G | 1 |
| López-Rivas, A | 1 |
| Ikezoe, T | 2 |
| Yang, Y | 1 |
| Bandobashi, K | 2 |
| Saito, T | 1 |
| Takemoto, S | 1 |
| Machida, H | 1 |
| Togitani, K | 2 |
| Koeffler, HP | 2 |
| Taguchi, H | 2 |
| Liu, JJ | 1 |
| Liu, PQ | 1 |
| Lin, DJ | 1 |
| Xiao, RZ | 1 |
| Huang, M | 1 |
| Li, XD | 1 |
| He, Y | 1 |
| Huang, RW | 1 |
| Yang, J | 1 |
| Nishioka, C | 1 |
| Tasaka, T | 1 |
| Taniguchi, A | 1 |
| Kuwayama, Y | 1 |
| Komatsu, N | 1 |
| Yokoyama, A | 1 |
| Kimura, M | 1 |
| Nagao, F | 1 |
| Okochi, K | 1 |
| Foadi, MD | 2 |
| Hardisty, RM | 2 |
| Lipchina, LP | 1 |
| Dvilansky, A | 1 |
| Zolotov, Z | 1 |
| Herzliker, B | 1 |
| Nathan, I | 1 |
| Fox, RM | 2 |
| Piddington, SK | 1 |
| Tripp, EH | 2 |
| Tattersall, MH | 5 |
| Taylor, IW | 1 |
| Mittler, U | 1 |
| Theuring, F | 1 |
| Kuliszkiewicz-Janus, M | 2 |
| Hiddemann, W | 4 |
| Büchner, T | 2 |
| Andreeff, M | 5 |
| Wörmann, B | 1 |
| Melamed, MR | 2 |
| Clarkson, BD | 8 |
| Matsumoto, SS | 1 |
| Yu, AL | 1 |
| Bleeker, LC | 1 |
| Bakay, B | 1 |
| Kung, FH | 1 |
| Nyhan, WL | 1 |
| Fairchild, RG | 1 |
| Miller, ME | 1 |
| Takeda, E | 2 |
| Hirose, M | 2 |
| Kuroda, Y | 2 |
| Ninomiya, T | 2 |
| Toshima, K | 1 |
| Watanabe, T | 1 |
| Ito, M | 1 |
| Naito, E | 1 |
| Miyao, M | 2 |
| Taylor, GM | 1 |
| Eggen, BM | 1 |
| Lamvik, JO | 1 |
| Vogler, WR | 2 |
| Whigham, EA | 1 |
| Somberg, LB | 1 |
| Long, RC | 1 |
| Winton, EF | 1 |
| Hofmann, V | 1 |
| Berens, ME | 1 |
| Kanter, PM | 1 |
| Schwartz, HS | 1 |
| West, CR | 1 |
| Fox, RI | 1 |
| Hueniken, M | 1 |
| Fong, S | 1 |
| Behar, S | 1 |
| Royston, I | 1 |
| Singhal, SK | 1 |
| Thompson, L | 1 |
| Ochi, T | 1 |
| Takahashi, K | 1 |
| Ohsawa, M | 1 |
| Li, ZJ | 1 |
| Mamaev, NN | 2 |
| Podol'tseva, EI | 1 |
| Blumenreich, MS | 2 |
| Chou, TC | 3 |
| Vale, K | 2 |
| Young, CW | 2 |
| Woodcock, TM | 1 |
| O'Hehir, M | 1 |
| Yunis, JJ | 1 |
| Howell, SB | 2 |
| Streifel, JA | 1 |
| Pfeifle, CE | 1 |
| Schornagel, JH | 2 |
| Leyva, A | 1 |
| Pinedo, HM | 1 |
| Seigneurin, D | 1 |
| Hollard, D | 1 |
| Tisdale, MJ | 1 |
| Jack, GW | 1 |
| Eridani, S | 1 |
| Fram, R | 1 |
| Major, P | 1 |
| Egan, E | 1 |
| Beardsley, P | 2 |
| Rosenthal, D | 1 |
| Kufe, D | 1 |
| Olofsson, T | 1 |
| Olsson, I | 1 |
| Sugden, PJ | 1 |
| Lilleyman, JS | 1 |
| Taetle, R | 1 |
| Mendelsohn, J | 1 |
| Kufe, DW | 1 |
| Karp, D | 1 |
| Parker, L | 1 |
| Rosowsky, A | 1 |
| Canellos, G | 1 |
| Harris, PJ | 1 |
| Abe, I | 1 |
| Saito, S | 1 |
| Hori, K | 1 |
| Suzuki, M | 1 |
| Sato, H | 1 |
| Da, WM | 1 |
| Stolc, V | 1 |
| Murphy, SB | 1 |
| Dahl, GV | 1 |
| George, SL | 1 |
| Karas, J | 1 |
| Look, AT | 1 |
| Simone, JV | 1 |
| Holden, L | 1 |
| Hoffbrand, AV | 2 |
| Wu, RT | 1 |
| Tanaka, N | 1 |
| Amadori, S | 2 |
| Petti, MC | 2 |
| Mastrovincenzo, C | 2 |
| Testa, MG | 2 |
| Antonelli, A | 1 |
| Mandelli, F | 2 |
| Preisler, HD | 6 |
| Yoshida, T | 1 |
| Hattori, KI | 1 |
| Nakamura, S | 1 |
| Mitamura, E | 1 |
| Kobayashi, S | 1 |
| Ohtake, S | 1 |
| Tanimoto, K | 1 |
| Galand, P | 1 |
| Del Bino, G | 1 |
| Morret, M | 1 |
| Capel, P | 1 |
| Degraef, C | 1 |
| Fokan, D | 1 |
| Feremans, W | 1 |
| Gangemi, RM | 1 |
| Tiso, M | 1 |
| Marchetti, C | 1 |
| Severi, AB | 1 |
| Fabbi, M | 1 |
| Ezaki, K | 1 |
| Tsuzuki, M | 1 |
| Katsuta, I | 1 |
| Maruyama, F | 1 |
| Kojima, H | 1 |
| Okamoto, M | 1 |
| Nomura, T | 1 |
| Wakita, M | 1 |
| Miyazaki, H | 1 |
| Sobue, R | 1 |
| Fukuda, T | 1 |
| Kakihara, T | 1 |
| Kamishima, T | 1 |
| Ohnishi, Y | 1 |
| Naito, M | 1 |
| Kishi, K | 1 |
| Shibata, A | 1 |
| Tsuruo, T | 1 |
| Volpi, N | 1 |
| Petrini, M | 2 |
| Conte, A | 1 |
| Valentini, P | 1 |
| Venturelli, T | 1 |
| Bolognani, L | 1 |
| Ronca, G | 1 |
| Lee, CW | 1 |
| Wen, D | 1 |
| Boissel, JP | 1 |
| Showers, M | 1 |
| Ruch, BC | 1 |
| Bunn, HF | 1 |
| Galimberti, S | 1 |
| Bianchi, F | 1 |
| Bernardini, N | 1 |
| Mattii, L | 1 |
| Dolfi, A | 1 |
| Lupetti, M | 1 |
| Mollinedo, F | 1 |
| Martínez-Dalmau, R | 1 |
| Modolell, M | 1 |
| Gong, J | 1 |
| Traganos, F | 1 |
| Darzynkiewicz, Z | 1 |
| Miyachi, H | 1 |
| Ma, L | 1 |
| Takemura, Y | 1 |
| Kobayashi, H | 1 |
| Hirahara, I | 1 |
| Sonehara, H | 1 |
| Ando, Y | 1 |
| McGuire, JJ | 1 |
| Canestrari, JG | 1 |
| Nagel, GS | 1 |
| Barnes, MJ | 1 |
| Taylor, GA | 1 |
| Newell, DR | 1 |
| Smith, DM | 1 |
| Dou, QP | 1 |
| McCubrey, JA | 1 |
| Steelman, LS | 1 |
| Blalock, WL | 1 |
| Lee, JT | 1 |
| Moye, PW | 1 |
| Chang, F | 1 |
| Pearce, M | 1 |
| Shelton, JG | 1 |
| White, MK | 1 |
| Franklin, RA | 1 |
| Pohnert, SC | 1 |
| Mozart, M | 1 |
| Scuderi, R | 1 |
| Celsing, F | 1 |
| Aguilar-Santelises, M | 1 |
| Hansen, D | 1 |
| Stadler, J | 1 |
| Lange Wantzin, G | 1 |
| Bertino, JR | 2 |
| Caligaris, F | 1 |
| Marinone, C | 1 |
| Masera, P | 2 |
| Matera, L | 1 |
| Arlin, Z | 1 |
| Phillips, FS | 1 |
| Tannock, I | 1 |
| Knapp, MR | 1 |
| Severinson-Gronowicz, E | 1 |
| Schröder, J | 1 |
| Strober, S | 1 |
| Hattori, K | 1 |
| De Francesco, A | 1 |
| Chierichini, A | 1 |
| Stadecker, MJ | 1 |
| Calderon, J | 1 |
| Karnovsky, ML | 1 |
| Unanue, ER | 1 |
| Hoelzer, D | 3 |
| Schmücker, H | 1 |
| Kurrle, E | 1 |
| Hirschmann, WD | 1 |
| Gross, R | 1 |
| Gerchak, D | 1 |
| Mamaeva, SE | 1 |
| Afanas'ev, BV | 1 |
| Gaponov, GG | 1 |
| Zittoun, R | 3 |
| Bouchard, M | 2 |
| Facquet-Danis, J | 2 |
| Diaz-Mayo, C | 1 |
| Percie-du-Sert, M | 2 |
| Bousser, J | 2 |
| Hirt, A | 1 |
| Wagner, HP | 3 |
| Sarna, G | 1 |
| Omine, M | 2 |
| Karp, JE | 1 |
| Burke, PJ | 2 |
| Pauly, JL | 2 |
| Burchardt, K | 1 |
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| Slezak, P | 1 |
| Vincent, PC | 2 |
| Gunz, FW | 1 |
| Pappas, A | 1 |
| Rosenoer, VM | 1 |
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| Tripp, E | 1 |
| Fuska, J | 1 |
| Proksa, B | 1 |
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| Neth, R | 1 |
| Garbrecht, M | 1 |
| Mertelsmann, R | 2 |
| Mitani, S | 1 |
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| Sheehy, PF | 1 |
| Fried, J | 4 |
| Dowling, MD | 2 |
| Freisheim, JH | 1 |
| Ratnam, M | 1 |
| McAlinden, TP | 1 |
| Prasad, KM | 1 |
| Williams, FE | 1 |
| Westerhof, GR | 1 |
| Jansen, G | 1 |
| Mäki, T | 1 |
| Andersson, LC | 1 |
| Kontula, KK | 1 |
| Arnér, ES | 1 |
| Spasokoukotskaja, T | 1 |
| Eriksson, S | 1 |
| Najid, A | 1 |
| Simon, A | 1 |
| Delage, C | 1 |
| Chulia, AJ | 1 |
| Rigaud, M | 1 |
| Bokhari, SA | 1 |
| Raza, A | 5 |
| Arsura, M | 1 |
| Introna, M | 1 |
| Passerini, F | 1 |
| Mantovani, A | 1 |
| Golay, J | 1 |
| Rowley, PT | 2 |
| Farley, BA | 2 |
| LaBella, S | 1 |
| Giuliano, R | 1 |
| Leary, JF | 1 |
| Hintz-Obertreis, P | 1 |
| Krumwieh, D | 1 |
| Seiler, FR | 1 |
| Olson, AC | 1 |
| Berdel, WE | 4 |
| Okamoto, S | 1 |
| Glasser, L | 1 |
| Panella, TJ | 1 |
| Huang, AT | 1 |
| Santoli, D | 1 |
| Tweardy, DJ | 1 |
| Ferrero, D | 1 |
| Kreider, BL | 1 |
| Rovera, G | 1 |
| Moriconi, WJ | 1 |
| Slavik, M | 1 |
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| Lazarus, HM | 1 |
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| Botti, RE | 1 |
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| Poulter, L | 1 |
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| Chuang, RY | 1 |
| Israel, M | 1 |
| Chuang, LF | 1 |
| Umeda, M | 1 |
| Shirai, T | 1 |
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| Nilsson, K | 1 |
| Platzer, E | 1 |
| Welte, K | 1 |
| Gabrilove, JL | 1 |
| Lu, L | 1 |
| Harris, P | 1 |
| Moore, MA | 1 |
| Frick, LW | 1 |
| Nelson, DJ | 1 |
| St Clair, MH | 1 |
| Furman, PA | 1 |
| Krenitsky, TA | 1 |
| O'Dwyer, PJ | 1 |
| King, SA | 1 |
| Hoth, DF | 1 |
| Leyland-Jones, B | 1 |
| Maheshwari, Y | 1 |
| Yasin, Z | 1 |
| Mandava, N | 1 |
| Mayers, G | 1 |
| Schick, HD | 3 |
| Fromm, M | 2 |
| Fink, U | 3 |
| Jehn, U | 1 |
| Ulm, K | 2 |
| Reichert, A | 3 |
| Eibl, H | 1 |
| Unger, C | 1 |
| Rastetter, J | 4 |
| Pahlke, W | 1 |
| Bicker, U | 1 |
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| Lebacq, AM | 1 |
| Fondu, P | 1 |
| Mandelbaum, IM | 1 |
| Mauro, F | 1 |
| Göhde, W | 1 |
| Schumann, J | 1 |
| Teodori, L | 1 |
| Spanò, M | 1 |
| Pileri, S | 1 |
| Gerdes, J | 1 |
| Rivano, M | 1 |
| Tazzari, PL | 1 |
| Magnani, M | 1 |
| Gobbi, M | 1 |
| Stein, H | 1 |
| Ross, DD | 1 |
| Thompson, BW | 1 |
| Joneckis, CC | 1 |
| Akman, SA | 1 |
| Schiffer, CA | 1 |
| Foa, P | 1 |
| Maiolo, AT | 1 |
| Baldini, L | 1 |
| Quarto di Palo, F | 1 |
| Starace, G | 1 |
| Kahilainen, L | 1 |
| Bergstrom, D | 1 |
| Kangas, L | 1 |
| Vilpo, JA | 2 |
| Ribéreau-Gayon, G | 1 |
| Jung, ML | 1 |
| Di Scala, D | 1 |
| Beck, JP | 1 |
| el-Assouli, SM | 1 |
| Tanaka, M | 1 |
| Kimura, K | 1 |
| Edelstein, M | 1 |
| Valeriote, F | 1 |
| Ucar, K | 1 |
| Heikkilä, R | 1 |
| Iversen, JG | 1 |
| Godal, T | 1 |
| Morris, CM | 1 |
| Fitzgerald, PH | 1 |
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| Fox, BM | 1 |
| Spiegel, JF | 1 |
| Gutierrez, PL | 1 |
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| Zittoun, J | 1 |
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| Abbatt, JD | 1 |
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| Brunner, G | 1 |
| Heimpel, H | 3 |
| McCulloch, EA | 1 |
| Mak, TW | 1 |
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| Till, JE | 1 |
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| Höcker, P | 2 |
| Pittermann, E | 2 |
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| Moser, K | 2 |
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| Musatti, CC | 1 |
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| Rabinowitz, Y | 1 |
| Wilhite, BA | 1 |
| Lee, SH | 1 |
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| Zatz, MM | 1 |
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| Adams, A | 1 |
| Klein, G | 2 |
| Weisenthal, LM | 1 |
| Ruddon, RW | 1 |
| Smith, RG | 1 |
| Whang-Peng, J | 1 |
| Gallo, RC | 1 |
| Levine, P | 1 |
| Ting, RC | 1 |
| Yamada, S | 1 |
| Shimizu, S | 1 |
| Tsuchiya, T | 1 |
| Toma, M | 1 |
| Sawa, Y | 1 |
| Burns, CP | 2 |
| Armentrout, SA | 1 |
| Stjernholm, RL | 2 |
| Schollenberger, S | 1 |
| Taureck, D | 1 |
| Wilmanns, W | 3 |
| Kozinets, GI | 2 |
| Gerasimova, NA | 1 |
| Dul'tsina, SM | 1 |
| Kovaleva, LG | 1 |
| Diggs, CH | 1 |
| Owens, AH | 1 |
| Golde, DW | 1 |
| Cline, MJ | 2 |
| Faille, A | 2 |
| Najean, Y | 2 |
| Bernard, J | 1 |
| Micu, D | 1 |
| Mihăilescu, E | 1 |
| Răiciulescu, N | 1 |
| Cheţa, D | 1 |
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| Feinendegen, LE | 1 |
| Lampkin, BC | 2 |
| Rapoport, GL | 1 |
| Friedkin, M | 1 |
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| Kozlov, EA | 1 |
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| Kondrat'eva, NA | 1 |
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| Tsuruoka, N | 1 |
| Shimizu, M | 1 |
| Catovsky, D | 1 |
| Pettit, JE | 1 |
| Galetto, J | 1 |
| Okos, A | 1 |
| Galton, DA | 1 |
| Andersen, V | 1 |
| Weeke, E | 1 |
| Freireich, EJ | 1 |
| Gehan, EA | 1 |
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| Hersh, EM | 1 |
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| Gutterman, JU | 1 |
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| Queiser, U | 1 |
| Olischläger, A | 1 |
| Koffler, D | 1 |
| Agnello, V | 1 |
| Winchester, R | 1 |
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| Taylor, BA | 1 |
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| Schmitt, G | 1 |
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| Löhr, E | 1 |
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| Taylor, G | 1 |
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| Ernst, P | 2 |
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| Klein, HO | 1 |
| Lennartz, KJ | 1 |
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20 reviews available for thymidine and Leukemia
| Article | Year |
|---|---|
BIOCHEMISTRY OF THE WHITE BLOOD CELL.
Topics: Acid Phosphatase; Alkaline Phosphatase; Biochemical Phenomena; Biochemistry; Carbohydrate Metabolism | 1964 |
Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia?
Topics: Acute Disease; Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemical Fractionation; DN | 1983 |
Is there a role for thymidine in cancer chemotherapy?
Topics: Cytarabine; Drug Therapy, Combination; Fluorouracil; Humans; Kinetics; Leukemia; Methotrexate; Neopl | 1982 |
Metabolism of 1-beta-D-arabinofuranosylcytosine in human leukemic cells.
Topics: Bone Marrow; Cytarabine; DNA, Neoplasm; Drug Therapy, Combination; Female; Humans; In Vitro Techniqu | 1977 |
Cell kinetics and chemotherapy: a critical review.
Topics: Animals; Autoradiography; Bone Marrow Cells; Cell Cycle; Cell Division; Clone Cells; Drug Administra | 1978 |
[Lymphocyte culture. Methods and clinical application].
Topics: B-Lymphocytes; Cell Migration Inhibition; Cells, Cultured; Culture Media; Cytological Techniques; DN | 1975 |
Cellular dynamics of leukemias.
Topics: Antibodies, Monoclonal; Antigens, Differentiation; Antigens, Neoplasm; Bone Marrow; Bromodeoxyuridin | 1990 |
Role of thymidine in biochemical modulation: a review.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Aspartic A | 1987 |
Considerations in the design of possible cell cycle effective drugs.
Topics: Alkylating Agents; Aneuploidy; Antimetabolites, Antineoplastic; Antineoplastic Agents; Bromodeoxyuri | 1986 |
Cytosine arabinoside in experimental combination therapy.
Topics: Aminoacridines; Amsacrine; Animals; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosyl | 1985 |
Leukemic cellular proliferation: a perspective.
Topics: Antigens, Surface; Cell Cycle; Cell Differentiation; Cell Membrane; Clone Cells; DNA, Neoplasm; Flow | 1985 |
Cell division and disseminated neoplastic disease in man: a review.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Survival; Cricet | 1970 |
[Proliferation of bone marrow and peripheral blood cells in leukemia and under normal conditions (review of the literature)].
Topics: Animals; Autoradiography; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Dogs; F | 1972 |
[The combined application of cytophotometric and autoradiographic methods in the study of the proliferation of normal and distrubed human haemopoietic cell systems (author's transl)].
Topics: Anemia, Aplastic; Anemia, Hemolytic, Congenital; Anemia, Macrocytic; Autoradiography; Cell Division; | 1973 |
[RNA metabolism in leukemic cells (author's transl)].
Topics: Animals; Chromatin; Dactinomycin; DNA-Directed RNA Polymerases; Humans; Leukemia; Nucleic Acid Hybri | 1974 |
Chemotherapy and the life cycle of leukaemic cells. A comparison between the growth characteristics of human acute leukaemia and the murine leukaemia L 1210.
Topics: Anilides; Animals; Cell Division; Cyclophosphamide; Cytarabine; DNA, Neoplasm; Fluorouracil; Humans; | 1969 |
Kinetics of normal and leukemic leukocyte populations and relevance to chemotherapy.
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Bone Marrow Cells; Cell Division; Cytarabine; Hem | 1970 |
[Cell kinetics in acute leukemia].
Topics: Acute Disease; Bone Marrow Cells; Humans; Kinetics; Leukemia; Mitosis; Thymidine; Tritium | 1971 |
In search of a key.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Cricetinae; DNA, Neoplasm; Drug Combinations; Human | 1971 |
Relevance of in vitro tests for predicting responsiveness to antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Membrane Permeability; DNA, Neoplasm; Drug Resistanc | 1971 |
2 trials available for thymidine and Leukemia
| Article | Year |
|---|---|
An in vitro method which assesses corneal epithelial toxicity due to antineoplastic, preservative and antimicrobial agents.
Topics: Adult; Aged; Aminoglycosides; Animals; Antineoplastic Agents; Antiviral Agents; Cells, Cultured; Cor | 1989 |
Extracorporeal irradiation of the blood: clinical applications.
Topics: Blood Cells; Cesium Isotopes; Clinical Trials as Topic; Cobalt Radioisotopes; Cytidine; Erythrocytes | 1974 |
292 other studies available for thymidine and Leukemia
| Article | Year |
|---|---|
Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis.
Topics: Animals; Cell Line; Citric Acid Cycle; Dimerization; DNA, Mitochondrial; Fumarates; Humans; Leukemia | 2021 |
Clinical value of the flow cytometric method for measuring lymphocyte subset activation: spontaneous activation of T-cell subpopulations is associated with acute GvHD.
Topics: Bone Marrow Transplantation; Child; Flow Cytometry; Follow-Up Studies; Graft vs Host Disease; Humans | 2003 |
[Incorporation of thymidine labeled with tritium into the elements of normal and leukemic bone marrow. Radioautographic investigations].
Topics: Autoradiography; Bone Marrow; Humans; Leukemia; Nucleosides; Nucleotides; Thymidine; Tritium | 1959 |
Thymidine phosphorylation and deoxyribonucleic acid synthesis in human leukaemic cells.
Topics: DNA; DNA Replication; Leukemia; Nucleosides; Nucleotides; Phosphorylation; Thymidine | 1962 |
Study of the effect of therapy on cells in the blood of leukemic patients capable of incorporating H3-thymidine.
Topics: Antineoplastic Agents; Blood Cells; DNA; Humans; Leukemia; Nucleosides; Nucleotides; Thymidine | 1962 |
The DNA metabolism studied by employing tritiated thimidine in acute and chronic leukemias.
Topics: DNA; DNA, Neoplasm; Humans; Leukemia; Leukemia, Lymphoid; Lymphocytes; Neoplasms; Thymidine | 1962 |
Remarks on DNA synthesis in normal and leukaemic cells.
Topics: DNA; DNA, Neoplasm; Leukemia; Leukocytes; Lymph Nodes; Spleen; Thymidine | 1962 |
Incorporation of labeled metabolites into leukemic cells.
Topics: Animals; Blood Cells; Bone Marrow; Carcinoma, Ehrlich Tumor; DNA; DNA, Neoplasm; Humans; Leukemia; P | 1962 |
Estimation of phases of the life cycle of leukemic cells from labeling in human beings in vivo with tritiated thymidine.
Topics: Cell Division; Humans; Leukemia; Lymphocytes; Thymidine | 1963 |
PROLIFERATIVE OF LEUKEMIC CELLS STUDIED WITH TRITIATED THYMIDINE IN VITRO.
Topics: DNA; DNA, Neoplasm; Humans; In Vitro Techniques; Leukemia; Leukemia, Myeloid; Leukocytes; Neoplasms; | 1963 |
UPTAKE OF MAMMALIAN CHROMOSOMES BY MAMMALIAN CELLS.
Topics: Animals; Autoradiography; Cell Nucleus; Chromosomes; Chromosomes, Mammalian; Coloring Agents; Cytopl | 1963 |
IN VIVO INCORPORATION OF TRITIATED THYMIDINE IN ACUTE LEUKAEMIS CHROMOSOMES.
Topics: Chromosomes; Leukemia; Leukemia, Myeloid; Metabolism; Research; Thymidine; Tritium | 1963 |
THE INCORPORATION OF THE TRITIATED THYMIDINE INTO DEOXYRIBONUCLEIC ACID OF MOUSE LEUKEMIC CELLS.
Topics: Animals; Autoradiography; Cell Nucleus; DNA; DNA, Neoplasm; Leukemia; Leukemia, Experimental; Metabo | 1963 |
[POSSIBILITY OF LABELING, USING TRITIATED PRECURSORS, THE CHROMOSOMES OF HUMAN LEUKEMIC CELLS].
Topics: Autoradiography; Chromosomes; DNA; DNA, Neoplasm; Humans; Leukemia; Leukocytes; Thymidine; Tritium | 1963 |
DNA REPLICATION PATTERNS OF HUMAN CHROMOSOMES.
Topics: Autoradiography; Cell Division; Chromosomes; Chromosomes, Human; DNA; DNA Replication; Down Syndrome | 1963 |
THE BOVINE LEUKOCYTE--LEUKOKINETIC STUDIES IN NORMAL, LEUKEMIC, AND MASTITIC COWS.
Topics: Animals; Cattle; DNA; Female; Leukemia; Leukemia, Experimental; Leukocytes; Mastitis; Mastitis, Bovi | 1964 |
THE GENERATION TIME OF THE LEUKEMIC MYELOBLASTS IN VIVO IN FOWL LEUKEMIA.
Topics: Animals; Autoradiography; Cell Division; DNA; DNA, Neoplasm; Granulocyte Precursor Cells; Leukemia; | 1963 |
UPTAKE OF TRITITATED THYMIDINE BY LEUKEMIC CELLS: EFFECT OF VARIOUS LEUKOCYTE PREPARATIONS.
Topics: Humans; Leukemia; Leukemia, Myeloid; Leukocytes; Metabolism; Research; Thymidine; Tritium | 1964 |
THYMIDINE CATABOLISM BY NORMAL AND LEUKEMIC HUMAN LEUKOCYTES.
Topics: Chondrosarcoma; Chromatography; Glucosyltransferases; Hodgkin Disease; Humans; Leukemia; Leukemia, L | 1964 |
EFFECT OF DEOXYCYTIDINE ON THE RATE OF BIOSYNTHESIS OF PHOSPHORYLATED DERIVATIVES OF THYMIDINE.
Topics: Carbon Isotopes; Chromatography; Deoxycytidine; Formates; Idoxuridine; Leukemia; Leukemia, Experimen | 1964 |
LEUCOCYTE CULTURES WITH PHYTOHAEMAGGLUTININ IN CHRONIC LYMPHATIC LEUKAEMIA.
Topics: Cell Division; Leukemia; Leukemia, Lymphoid; Leukocyte Count; Leukocytes; Lymphocytes; Phytohemagglu | 1964 |
INHIBITION OF TRITIATED THYMIDINE INCORPORATION INTO DNA BY ALKALINE PHOSPHATASE PREPARATIONS.
Topics: Alkaline Phosphatase; Animals; Bone Marrow; DNA; Dogs; Female; Histocytochemistry; Intestines; Leuke | 1964 |
CHARACTERISTICS OF CELL PROLIFERATION IN A PATIENT WITH ACUTE LEUKAEMIA.
Topics: Bone Marrow Cells; Bone Marrow Examination; Cell Division; Child; Humans; Leukemia; Neoplasms; Thymi | 1964 |
CYTOCHEMICAL AND AUTORADIOGRAPHIC STUDIES ON NORMAL AND LEUKAEMIC CELLS IN SHORT-TERM TISSUE CULTURES.
Topics: Autoradiography; Chemical Phenomena; Chemistry; Coloring Agents; DNA; DNA, Neoplasm; Glycogen; Leuke | 1964 |
GRANULOCYTOPOIESIS. II. EMERGENCE AND PATTERN OF LABELING OF NEUTROPHILIC GRANULOCYTES IN HUMANS.
Topics: Anemia; Anemia, Pernicious; Glioblastoma; Hematopoiesis; Humans; Leukemia; Lymphoma; Lymphoma, Non-H | 1964 |
PHOSPHORYLATION OF THYMIDINE DIPHOSPHATE IN RESTING AND PROLIFERATING MAMMALIAN CELLS.
Topics: DNA; Erythrocytes; Leukemia; Liver; Metabolism; Mice; Nucleotides; Phosphorylation; Research; Spleen | 1964 |
ENZYME STUDIES IN VIRUS-INDUCED NEOPLASMS. I. THE EFFECT OF A MURINE LEUKEMIA ON ENZYMES OF ONE-CARBON METABOLISM AND ON PHOSPHOMONOESTERASES.
Topics: Alkaline Phosphatase; Animals; Carbon; Esterases; Folic Acid; Histocytochemistry; Leukemia; Leukemia | 1964 |
STUDIES OF THE INCORPORATION OF PYRIMIDINES INTO DNA IN SINGLE LEUKAEMIC AND OTHER PROLIFERATING LEUCOCYTES.
Topics: Autoradiography; DNA; DNA, Neoplasm; Humans; Infectious Mononucleosis; Leukemia; Leukocytes; Metabol | 1965 |
THE INCORPORATION AND DEGRADATION OF PYRIMIDINE DNA PRECURSORS BY HUMAN LEUCOCYTES.
Topics: Autoradiography; Carbon Isotopes; Cytosine Nucleotides; Deoxyuridine; DNA; Humans; Infectious Mononu | 1964 |
[KINETICS OF CELLULAR PROLIFERATION IN LEUKEMIA AND CANCER].
Topics: Cell Division; Humans; Hyperplasia; Kinetics; Leukemia; Neoplasms; Neoplastic Cells, Circulating; Th | 1964 |
SERIAL OBSERVATIONS ON THE METABOLISM OF PERIPHERAL ACUTE LEUKEMIC LEUKOCYTES.
Topics: Adolescent; Child; Humans; Leukemia; Leukocytes; Metabolism; Nucleic Acids; Nucleosides; Radiometry; | 1965 |
MEASUREMENT OF DNA-SYNTHESIS TIME IN MYELOID-ERYTHROID PRECURSORS.
Topics: Animals; Autoradiography; Bone Marrow Cells; Carbon Isotopes; DNA; DNA Replication; Dogs; Leukemia; | 1965 |
IMMUNOLOGIC AND CYTOGENETIC STUDIES OF CHRONIC LYMPHOCYTIC LEUKEMIC CELLS.
Topics: Autoradiography; Blood Cell Count; Blood Protein Electrophoresis; Cell Division; Chromosomes; Cytoge | 1965 |
The metabolism of thymidine by murine leukemic lymphoblasts (L5178Y).
Topics: Animals; Cell Count; Leukemia; Leukemia, Lymphoid; Lymphocytes; Mice; Nucleosides; Nucleotides; Thym | 1962 |
Effect of folic acid on in vitro uptake of labeled thymidine by leukemic cells.
Topics: Biochemical Phenomena; Folic Acid; In Vitro Techniques; Leukemia; Lymphoma; Lymphoma, Non-Hodgkin; N | 1961 |
Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c | 2004 |
Oridonin, a diterpenoid purified from Rabdosia rubescens, inhibits the proliferation of cells from lymphoid malignancies in association with blockade of the NF-kappa B signal pathways.
Topics: Adult; Aged; Aged, 80 and over; Animals; Apoptosis; bcl-X Protein; Blotting, Western; Cell Line; Cel | 2005 |
Downregulation of cyclooxygenase-2 expression and activation of caspase-3 are involved in peroxisome proliferator-activated receptor-gamma agonists induced apoptosis in human monocyte leukemia cells in vitro.
Topics: Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Chromans; Cyclooxygenase 2; DNA, Neoplasm | 2007 |
AZD1152, a novel and selective aurora B kinase inhibitor, induces growth arrest, apoptosis, and sensitization for tubulin depolymerizing agent or topoisomerase II inhibitor in human acute leukemia cells in vitro and in vivo.
Topics: Animals; Antibiotics, Antineoplastic; Apoptosis; Aurora Kinase A; Aurora Kinase B; Aurora Kinases; C | 2007 |
[Autoradiographic studies on DNA, RNA and protein synthesis in vitro of human bone marrow cells].
Topics: Anemia; Autoradiography; Bone Marrow; Bone Marrow Cells; DNA; Humans; In Vitro Techniques; Leucine; | 1966 |
[Autoradiography with 3H-thymidine in study of leukemia cells of children. 2. Correlation of the proliferation rate and the clinical course].
Topics: Adolescent; Autoradiography; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Female; Humans | 1966 |
[H3-thymidine autoradiographic study of cell proliferation in patients with acute leukemia in childhood].
Topics: Adolescent; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Child, Preschool; | 1966 |
DNA synthesis and DNA content of leucocytes in acute leukaemia.
Topics: Autoradiography; Cell Division; DNA; Humans; Leukemia; Leukocytes; Polyploidy; Thymidine; Tritium | 1967 |
[Mitotic cycles of leukemic cells].
Topics: Animals; DNA, Neoplasm; Humans; Leukemia; Leukemia, Experimental; Lymphocytes; Lymphoma; Mice; Mitos | 1967 |
Kinetics of leukemic cell proliferation.
Topics: Bone Marrow; Humans; Kinetics; Leukemia; Radiation Injuries; Thymidine; Tritium | 1967 |
Effects of ethanol, CBD and delta 'THC on proliferation of K-562 cells.
Topics: Cannabinoids; Cell Count; Cell Division; Cell Line; Dronabinol; Ethanol; Humans; Leukemia; Thymidine | 1984 |
Ecto-adenosine triphosphatase deficiency in cultured human T and null leukemic lymphocytes. A biochemical basis for thymidine sensitivity.
Topics: Adenosine Triphosphatases; Cell Transformation, Viral; Cells, Cultured; Deoxyadenosines; Deoxyguanos | 1981 |
Methotrexate cytotoxicity in cultured human leukemic cells studied by flow cytometry.
Topics: Acridine Orange; Cells, Cultured; Cytological Techniques; DNA; Dose-Response Relationship, Drug; Flu | 1981 |
[Proliferation kinetic findings in acute juvenile leukemia].
Topics: Acute Disease; Autoradiography; Cell Division; Cell Nucleus; Child; Hematopoietic Stem Cells; Humans | 1981 |
[Determination of the sensitivity of leukemic blasts to cytostatic agents by means of an isotope method].
Topics: Antineoplastic Agents; DNA, Neoplasm; Hematopoietic Stem Cells; Humans; Leukemia; Leukemia, Lymphoid | 1981 |
Bone marrow biopsy instead of 'marrow juice' for cell kinetic analysis. Comparison of bone marrow biopsy and aspiration material.
Topics: Acute Disease; Biopsy; Biopsy, Needle; Bone Marrow; DNA; Flow Cytometry; Humans; Interphase; Kinetic | 1982 |
Biochemical correlates of the differential sensitivity of subtypes of human leukemia to deoxyadenosine and deoxycoformycin.
Topics: Adenosine Deaminase; Adolescent; Deoxyadenine Nucleotides; Deoxyadenosines; Humans; Leukemia; Leukem | 1982 |
Ribonucleotide reductase and thymidine kinase activities in various cultured cell lines derived from hematologic malignancies.
Topics: Adolescent; Adult; Aged; Cell Division; Cell Line; Child; Child, Preschool; Female; Humans; Infant; | 1984 |
In vitro stimulation of cell-mediated cytotoxicity by acute leukaemias.
Topics: Cell Line; Cytotoxicity, Immunologic; Humans; Leukemia; Leukocyte Count; Lymphocyte Activation; Lymp | 1981 |
Dissociation between cytostatic and cytolytic activity of human monocytes towards K-562 cells.
Topics: Cell Line; Cytotoxicity, Immunologic; Humans; Leukemia; Monocytes; Thymidine; Tritium | 1984 |
The effect of alkyl-lysophospholipids on tritiated thymidine incorporation and clonogenicity in vitro of normal and leukemic human cells.
Topics: Bone Marrow Cells; Cell Line; Circadian Rhythm; Colony-Forming Units Assay; Humans; Leukemia; Lysoph | 1984 |
Test this patient's leukemic stem cells in a non-clonogenic chemosensitivity assay, treat according to standard protocols.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Cells, Cultured; Drug Evaluation, Pre | 1984 |
Functional and chemical markers of PCNU activity.
Topics: Animals; Antineoplastic Agents; Carmustine; DNA; Humans; Leukemia; Mice; Nitrosourea Compounds; Phen | 1983 |
A novel cell surface antigen (T305) found in increased frequency on acute leukemia cells and in autoimmune disease states.
Topics: Animals; Antigens, Surface; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Leukemia; Le | 1983 |
A mechanism for the stimulation by inorganic mercury of [3H] thymidine incorporation into DNA in cultured Molt-4F cells.
Topics: Cell Line; DNA, Neoplasm; Humans; Leucine; Leukemia; Mercury; Methotrexate; T-Lymphocytes; Thymidine | 1983 |
[Prediction of the response of patients with acute leukemia to chemotherapeutic agents by tritiated thymidine uptake by leukocytes].
Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Cytarabine; Female; Humans; Le | 1983 |
[Clinical and kinetic characteristics of a temporarily nonproliferating subpopulation of bone marrow blast cells from acute leukemia patients (based on data on DNA autoradiography and cytophotometry].
Topics: Acute Disease; Adolescent; Adult; Aged; Autoradiography; Bone Marrow; Cell Transformation, Neoplasti | 1983 |
Thymidine as a kinetic and biochemical modulator of 1-beta-D-arabinofuranosylcytosine in human acute nonlymphocytic leukemia.
Topics: Acute Disease; Adult; Cytarabine; Deoxycytidine; Female; Humans; Interphase; Kinetics; Leukemia; Mal | 1984 |
Effect of very high-dose thymidine infusions on leukemia and lymphoma patients.
Topics: Adult; Bone Marrow; Female; Flow Cytometry; Humans; Infusions, Parenteral; Kinetics; Leukemia; Lymph | 1984 |
Differences in the blast cells sensitivity to cytostatic drugs in various acute leukemia types and their clinical implications.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Female; Humans; Leukemia; Male; Middl | 1984 |
Comparative analysis of high-resolution chromosome techniques for leukemic bone marrows.
Topics: Bone Marrow; Chromosome Banding; Chromosomes, Human; Cytological Techniques; DNA; Humans; Leukemia; | 1982 |
Modulation of the cellular pharmacology and clinical toxicity of 1-beta-D-arabinofuranosylcytosine.
Topics: Arabinofuranosylcytosine Triphosphate; Cell Line; Cytarabine; Deoxyribonucleotides; DNA; Drug Therap | 1982 |
Use of the tritiated thymidine-labelling index of the myeloblast-promyelocyte pool for the identification of the leukemic population in oligoblastic leukemia.
Topics: Acute Disease; Autoradiography; Bone Marrow; Female; Humans; Leukemia; Leukemia, Myeloid, Acute; Mal | 1981 |
Differential sensitivity of normal and leukaemic haemopoietic cells to methionine deprivation by L-methioninase.
Topics: Adenosylmethionine Decarboxylase; Carbon-Sulfur Lyases; Hematopoietic Stem Cells; Homocysteine; Huma | 1983 |
A phase I-II study of combination therapy with thymidine and cytosine arabinoside.
Topics: Adolescent; Adult; Child; Child, Preschool; Cytarabine; Drug Evaluation; Drug Therapy, Combination; | 1983 |
Suppression of normal granulopoiesis in vitro by a leukemia-associated inhibitor (LAI) of acute and chronic leukemia.
Topics: Acute Disease; Bone Marrow Cells; Chronic Disease; Clone Cells; Colony-Forming Units Assay; Culture | 1980 |
Inhibitory effect of autologous plasma on the uptake of tritiated thymidine by leukaemic lymphoblasts and its relation to prognosis.
Topics: Acute Disease; Adolescent; Adult; Aged; Cells, Cultured; Child; Child, Preschool; Female; Humans; In | 1980 |
Thymidine as a chemotherapeutic agent: sensitivity of normal human marrow, peripheral blood T cells, and acute nonlymphocytic leukemia.
Topics: Acute Disease; Bone Marrow; Cell Cycle; Cell Transformation, Neoplastic; Colony-Forming Units Assay; | 1980 |
High-dose thymidine infusions in patients with leukemia and lymphoma.
Topics: Adolescent; Adult; Bone Marrow; Child; Hematopoietic Stem Cells; Hepatomegaly; Humans; Leukemia; Leu | 1980 |
Neutrophil product with lymphocyte activating factor activity.
Topics: Animals; Concanavalin A; Humans; Interleukin-1; Leukemia; Lymphocyte Activation; Mice; Neutrophils; | 1982 |
Mechanism of deoxycytidine rescue of thymidine toxicity in human T-leukemic lymphocytes.
Topics: Cell Division; Cell Line; Deoxycytidine; Deoxyribonucleotides; DNA Replication; Humans; Leukemia; Ly | 1980 |
Bone marrow cell count per cubic millimeter bone marrow: a new parameter for quantitating therapy-induced cytoreduction in acute leukemia.
Topics: Acute Disease; Bone Marrow; Cell Count; Cytarabine; Daunorubicin; Humans; Leukemia; Thioguanine; Thy | 1982 |
Role of dephosphorylation in accumulation of 1-beta-D-arabinofuranosylcytosine 5'-triphosphate in human lymphoblastic cell lines with reference to their drug sensitivity.
Topics: Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Cell Division; Cell Line; Cells, Cultured | 1982 |
[A preliminary report of a quick method for determining drug sensitivity of leukemic cells in vitro (author's transl)].
Topics: Adult; Antineoplastic Agents; Cell Division; DNA, Neoplasm; Female; Humans; In Vitro Techniques; Leu | 1982 |
Inhibitory effect of short-chain aliphatic acids on deoxythymidine incorporation into DNA in mitogen-stimulated and leukemic lymphocytes.
Topics: Acetates; Butyrates; Carboxylic Acids; DNA; Humans; Immunosuppressive Agents; Leukemia; Lymphocyte A | 1982 |
Determination of the significance of in vitro blast cell [3H]thymidine labelling indices obtained initially and serially during induction therapy of acute non-lymphocytic leukemia.
Topics: Acute Disease; Adolescent; Antineoplastic Agents; Autoradiography; Biopsy, Needle; Bone Marrow; Chil | 1982 |
Leukemia revisited.
Topics: Animals; Cell Division; DNA, Neoplasm; Exchange Transfusion, Whole Blood; Humans; Kinetics; Leukemia | 1981 |
Quantitation of chemotherapy-induced cytoreduction in acute leukemia.
Topics: Acute Disease; Bone Marrow; Cell Count; Drug Evaluation; Humans; Kinetics; Leukemia; Lymphoma; Oxida | 1981 |
Thymidine concentrations in human sera: variations in patients with leukaemia and megaloblastic anaemia.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Humans; Leukemia; Lymphoma; Radioimmunoassay; Thymidine | 1980 |
Effects of antitumor agents on DNA synthesis of mitogen-induced human lymphocytes, in comparison with leukemic cells.
Topics: Antineoplastic Agents; Cells, Cultured; DNA; DNA, Neoplasm; Humans; In Vitro Techniques; Leukemia; L | 1980 |
Blast cell kinetics and prognosis in acute nonlymphocytic leukemia.
Topics: Acute Disease; Bone Marrow; Humans; Kinetics; Leukemia; Mitosis; Mitotic Index; Prognosis; Thymidine | 1980 |
Clonogenic potential in vitro of proliferative and quiescent leukemic cells.
Topics: Acute Disease; Bone Marrow; Cell Division; Cells, Cultured; Clone Cells; Humans; Leukemia; Thymidine | 1980 |
A simple rapid autoradiography for 3H-thymidine labeling index and its application to therapy of adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Autoradiography; Cell Cycle; Cytarabine; Female; Humans; Leu | 1980 |
PCNA immunopositivity index as a substitute to 3H-thymidine pulse-labeling index (TLI) in methanol-fixed human lymphocytes.
Topics: Autoradiography; Cell Line; Histological Techniques; Humans; Immunohistochemistry; Ki-67 Antigen; Le | 1995 |
Taxol cytotoxicity on human leukemia cell lines is a function of their susceptibility to programmed cell death.
Topics: Apoptosis; Cycloheximide; Drug Resistance; Electrophoresis, Agar Gel; Flow Cytometry; Humans; Leukem | 1995 |
Interleukin-1 beta (IL-1 beta) and acute leukemia: in vitro proliferative response to IL-1 beta, IL-1 beta content of leukemic cells and treatment outcome.
Topics: Acute Disease; Adolescent; Adult; Aged; Female; Humans; Interleukin-1; Leukemia; Lymphocyte Activati | 1995 |
Characterization of newly established adriamycin resistant human leukemic cell lines (KY-ADR1 and KY-ADR2).
Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Surface; Antineoplastic Agents; ATP Binding Cassette | 1994 |
Effects of glycosaminoglycans on U-937 leukemia cell proliferation and differentiation: structure-function relationship.
Topics: Animals; Carbohydrate Conformation; Carbohydrate Sequence; Cattle; Cell Differentiation; Cell Divisi | 1994 |
Decrease in equilibrative uridine transport during monocytic differentiation of HL-60 leukaemia: involvement of protein kinase C.
Topics: Affinity Labels; Alkaloids; Binding Sites; Biological Transport; Cell Differentiation; Dilazep; Dipy | 1994 |
Erythropoietin structure-function relationships. Identification of functionally important domains.
Topics: Amino Acid Sequence; Animals; Biological Assay; Cell Division; Cell Line; Chlorocebus aethiops; Eryt | 1994 |
Scanning electron microscopy of multidrug resistant cells in haematological and mammary malignancies.
Topics: Acute Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Breas | 1993 |
Early and selective induction of apoptosis in human leukemic cells by the alkyl-lysophospholipid ET-18-OCH3.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Cell Death; DNA, Neoplasm; HeLa Cells; Humans; Leukemia; | 1993 |
Growth imbalance and altered expression of cyclins B1, A, E, and D3 in MOLT-4 cells synchronized in the cell cycle by inhibitors of DNA replication.
Topics: Cell Cycle; Cell Division; Cyclin B; Cyclin B1; Cyclin D3; Cyclins; DNA; DNA Replication; G1 Phase; | 1995 |
Microsatellite instability and clonal heterogeneity of MDR1 messenger RNA expression in trimetrexate-resistant human leukemia MOLT-3 cells developed in thymidine.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Resis | 1999 |
Characterization of the effect of AG337, a novel lipophilic thymidylate synthase inhibitor, on human head and neck and human leukemia cell lines.
Topics: Cell Cycle; Cell Division; Culture Media; Drug Resistance; Enzyme Inhibitors; Fetal Blood; Head and | 1999 |
Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells.
Topics: Adenine; Antimetabolites, Antineoplastic; Child; Guanine; Humans; Inosine; Leukemia; Methotrexate; P | 2000 |
Green tea polyphenol epigallocatechin inhibits DNA replication and consequently induces leukemia cell apoptosis.
Topics: Apoptosis; Catechin; Cell Cycle; Cell Division; DNA; Dose-Response Relationship, Drug; Flavonoids; F | 2001 |
Synergistic effects of pi3k/akt on abrogation of cytokine-dependency induced by oncogenic raf.
Topics: Animals; Blotting, Western; Cell Line; Cytokines; Dose-Response Relationship, Drug; Green Fluorescen | 2001 |
Nitric oxide induces apoptosis in NALM-6, a leukaemia cell line with low cyclin E protein levels.
Topics: Actins; Apoptosis; B-Lymphocytes; Blotting, Western; Cell Cycle; Cell Separation; Cyclin A; Cyclin D | 2001 |
Increased polyethylene glycol-mediated fusion competence in mitotic cells of a mouse lymphoid cell line.
Topics: Cell Fusion; Cell Line; Cell Membrane; Demecolcine; Leukemia; Lymphocyte Activation; Mitosis; Parain | 1977 |
Leucine incorporation into leukaemic blast cells.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Female; Humans; Leucine; Leukemia; Leukemia, Lymphoid; | 1979 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru | 1977 |
An approach to simultaneous immunofluorescent and autoradiographic analysis of human normal and neoplastic blood cells.
Topics: Adult; Autoradiography; Bone Marrow; Fluorescent Antibody Technique; Humans; Infectious Mononucleosi | 1977 |
Characterization of a spontaneous murine B cell leukemia (BCL1). II. Tumor cell proliferation and IgM secretion after stimulation by LPS.
Topics: Animals; B-Lymphocytes; Cell Transformation, Neoplastic; Dose-Response Relationship, Immunologic; Fe | 1979 |
[Problems in treatment for adult acute leukemia (author's transl)].
Topics: Acute Disease; Adult; Female; Humans; Immunity, Cellular; Leukemia; Male; Middle Aged; Prognosis; Th | 1977 |
Lack of prognostic significance of the pretreatment labeling and mitotic indices of marrow blasts in acute nonlymphocytic leukemia (ANLL).
Topics: Acute Disease; Adolescent; Adult; Aged; Bone Marrow; Child; Child, Preschool; Drug Therapy, Combinat | 1978 |
Synthesis and release of thymidine by macrophages.
Topics: Animals; Cell Line; Cells, Cultured; Chromatography, Gel; Chromatography, Thin Layer; Culture Media; | 1977 |
Re-entry of resting leukaemic blood cells into proliferation in human acute leukaemia during diffusion chamber culture.
Topics: Acute Disease; Cell Division; Cells, Cultured; Humans; Leukemia; Recurrence; Thymidine; Tritium | 1976 |
[Pretherapeutic sensitivity tests of human leukemia cells against cytostatic drugs in vitro in relation to the in vivo effects].
Topics: Antineoplastic Agents; Cell Transformation, Neoplastic; Cytarabine; Daunorubicin; Humans; In Vitro T | 1976 |
[Characteristics of DNA replication of the chromosomes of the bone marrow cells in patients with acute leukemia].
Topics: Acute Disease; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Chromosomes, H | 1976 |
[In vitro study of sensitivity of leukemic cells to cytotoxic drugs (anticytogram)].
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Asparaginase; Carbon Radioisotopes; C | 1975 |
Nuclear incorporation of radioactive DNA precursors and progression of cells through S. Combined radioautographic and cytophotometric studies on normal and leukaemic bone marrow and thoracic duct lymph cells of man.
Topics: Aged; Bone Marrow; Bone Marrow Cells; Cell Nucleus; Child; Child, Preschool; Deoxycytidine; DNA; Fem | 1975 |
Cytokinetics of human acute leukemia before and after chemotherapy.
Topics: Adolescent; Adult; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cells, Cultured; Chi | 1975 |
Influence of humoral regulators on proliferation and maturation of normal and leukemic cells.
Topics: Blood Specimen Collection; Bone Marrow; Bone Marrow Cells; Cell Differentiation; Cell Division; Cycl | 1976 |
Thymidine and uridine degradation by nucleosidases of cultured human lymphoblastoid cells.
Topics: Cell Survival; Cells, Cultured; Humans; Leukemia; Lymphocytes; N-Glycosyl Hydrolases; Thymidine; Uri | 1976 |
A case of lymphoma with T-cell characteristics.
Topics: B-Lymphocytes; Female; Humans; Immune Adherence Reaction; Lectins; Leukemia; Middle Aged; T-Lymphocy | 1975 |
Prediction of the response to chemotherapy in acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Antineoplastic Agents; Autoradiography; Bone Marrow; Bone Ma | 1975 |
Growth kinetics of solid tumors. Implications for chemotherapy.
Topics: Acute Disease; Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Colonic Neoplasms; Cul | 1975 |
Deoxyribonucleoside triphosphates in human cells: changes in disease and following exposure to drugs.
Topics: Adenosine Triphosphate; Antimetabolites; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell | 1975 |
New potential cytotoxic and antitumor substances I. In vitro effect of bikaverin and its derivatives on cells of certain tumors.
Topics: Adenine; Animals; Carcinoma, Ehrlich Tumor; Cells, Cultured; DNA, Neoplasm; In Vitro Techniques; Leu | 1975 |
[The effect of actinomycin d, acridine dyes and related substances on the biosynthesis of nucleic acids in normal and leukemic white blood cells. Comparative investigation in intact cells and in a cell-free system (author's transl)].
Topics: Acridines; Animals; Cell Membrane; Cell-Free System; Cells, Cultured; Dactinomycin; DNA; DNA-Directe | 1975 |
The effect of Fv-2 gene on the incorporation of thymidine in the mouse spleen.
Topics: Animals; Cell Membrane; DNA; Friend murine leukemia virus; Genes; Leukemia; Mice; Mice, Inbred C57BL | 1975 |
Studies of cellular proliferation in human leukemia. VIII. The generation time and growth fraction in lymphosarcoma in a leukemic phase during advanced and early relapsing disease.
Topics: Adult; Autoradiography; Cell Division; Chromosomes; Humans; Kinetics; Leukemia; Lymphoma, Non-Hodgki | 1975 |
Molecular events in the membrane transport of methotrexate in human CCRF-CEM leukemia cell lines.
Topics: Affinity Labels; Biological Transport, Active; Carrier Proteins; Folate Receptors, GPI-Anchored; Fol | 1992 |
Expression and function of beta-adrenergic receptors in human hematopoietic cell lines.
Topics: Blood Cells; Blotting, Southern; Cell Division; Cell Line; Cyclic AMP; DNA; DNA, Neoplasm; Humans; I | 1992 |
Selective assays for thymidine kinase 1 and 2 and deoxycytidine kinase and their activities in extracts from human cells and tissues.
Topics: Arabinonucleosides; Cladribine; Deoxycytidine; Deoxycytidine Kinase; Humans; Isoenzymes; Kinetics; L | 1992 |
A Calluna vulgaris extract 5-lipoxygenase inhibitor shows potent antiproliferative effects on human leukemia HL-60 cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Arachidonic Acid; Cell Division; Humans; Leukemia; Lipox | 1992 |
Novel derivation of total cell cycle time in malignant cells using two DNA-specific labels.
Topics: Biopsy, Needle; Bone Marrow; Cell Cycle; DNA-Binding Proteins; DNA, Neoplasm; Humans; Leukemia; Math | 1992 |
B-myb antisense oligonucleotides inhibit proliferation of human hematopoietic cell lines.
Topics: B-Lymphocytes; Base Sequence; Cell Division; Cell Line; DNA Replication; Dose-Response Relationship, | 1992 |
Single K562 human leukemia cells express and are inducible for both erythroid and megakaryocytic antigens.
Topics: Antigens, Differentiation; Butyrates; Butyric Acid; Erythrocytes; Flow Cytometry; Glycophorins; Hema | 1992 |
Development of a rapid, highly sensitive, non-radioactive assay system for hematopoietic growth factors.
Topics: Biological Assay; Cell Division; Cell Line; DNA Replication; Granulocyte-Macrophage Colony-Stimulati | 1991 |
Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results.
Topics: Acute Disease; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplan | 1990 |
Effect of thimerosal in leukemia, in leukemic cell lines, and on normal hematopoiesis.
Topics: Antilymphocyte Serum; Blast Crisis; Cell Differentiation; Cell Line; DNA Replication; Ethylmercury C | 1990 |
A suppressor lymphokine produced by human T leukemia cell lines. Partial characterization and spectrum of activity against normal and malignant hemopoietic cells.
Topics: Cell Cycle; Cell Division; Cell Line; DNA; Hematopoietic Stem Cells; Humans; Interferons; Interleuki | 1986 |
3-Deazauridine (NSC 126849): an interesting modulator of biochemical response.
Topics: 3-Deazauridine; Acute Disease; Animals; Antineoplastic Agents; Azacitidine; Cytarabine; Decitabine; | 1986 |
Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins.
Topics: Aminolevulinic Acid; Animals; Cell Survival; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leuk | 1989 |
Mixed lymphocyte cultures using automated blood cell counters.
Topics: Anemia, Aplastic; Bone Marrow Transplantation; Fanconi Anemia; Humans; Leukemia; Leukocyte Count; Ly | 1989 |
Nucleoside uptake and membrane fluidity studies on N-trifluoroacetyladriamycin-14-O-hemiadipate-treated human leukemia and lymphoma cells.
Topics: Doxorubicin; Electron Spin Resonance Spectroscopy; Humans; Leukemia; Lymphoma; Membrane Fluidity; Nu | 1989 |
[Relationship between Ara-C sensitivity of leukemic-colony forming units (L-CFU) and [3H] deoxycytidine suicide test of L-CFU].
Topics: Adult; Aged; Cell Survival; Cytarabine; Deoxycytidine; Female; Humans; Leukemia; Male; Middle Aged; | 1989 |
Effects of dialyzable leukocyte extracts (DLE) and inosine on stimulated lymphocytes.
Topics: Adenosine Triphosphate; Cell Line; Chemical Fractionation; Fibroblasts; Humans; Inosine; Leukemia; L | 1989 |
Behavior of activities of thymidine metabolizing enzymes in human leukemia-lymphoma cells.
Topics: Dihydrouracil Dehydrogenase (NAD+); Humans; Kinetics; Leukemia; Lymphocytes; Lymphoma; Oxidoreductas | 1989 |
The dynamic morphology of the transferrin-transferrin receptor system in human leukaemia/lymphoma cell lines and its relation to iron metabolism and cell proliferation.
Topics: Cell Division; Cell Line; Endocytosis; Humans; Iron; Leukemia; Lymphoma; Receptors, Cell Surface; Re | 1985 |
Biological activities of a human pluripotent hemopoietic colony stimulating factor on normal and leukemic cells.
Topics: Animals; Carcinoma; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Granul | 1985 |
Effects of 3'-azido-3'-deoxythymidine on the deoxynucleotide triphosphate pools of cultured human cells.
Topics: Antiviral Agents; Cell Line; Deoxyribonucleotides; Humans; Kinetics; Leukemia; Thymidine; Zidovudine | 1988 |
A new method for studying cell cycle characteristics in ANLL using double-labeling with BrdU and 3HTdr.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Autoradiography; Bromodeoxyuridine; Cell Cycle; DNA; Flu | 1987 |
Cytotoxic effects of ether lipids and derivatives in human nonneoplastic bone marrow cells and leukemic cells in vitro.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Survival; Cytotoxins; Humans; Leukemia; | 1987 |
Antineoplastic activity of the thioether lysophospholipid derivative BM 41.440 in vitro.
Topics: Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cell Survival; Humans; Leukemia; Lysophosphol | 1987 |
Inhibitory effect of dipyridamole on the growth of various human hematologic malignant cell lines.
Topics: Adolescent; Adult; Child; Child, Preschool; Dipyridamole; DNA, Neoplasm; Female; Humans; Infant; Inf | 1986 |
Deoxythymidine and deoxycytidine incorporation into DNA in B leukemic cells.
Topics: B-Lymphocytes; Deoxycytidine; Deoxycytidine Kinase; DNA; Humans; Leukemia; Phenotype; Thymidine | 1986 |
Immunohistochemical determination of growth fractions in human permanent cell lines and lymphoid tumours: a critical comparison of the monoclonal antibodies OKT9 and Ki-67.
Topics: Antibodies, Monoclonal; Cell Division; Cell Line; DNA, Neoplasm; Fluorescent Antibody Technique; Hum | 1987 |
Studies of ara-C metabolism in acute leukemia.
Topics: Acute Disease; Arabinofuranosylcytosine Triphosphate; Bromodeoxyuridine; Cell Line; Cytarabine; DNA, | 1987 |
Cyclosporin A antileukemic activity: mode of action on target cells.
Topics: Cell Cycle; Cell Line; Cell Survival; Cyclosporins; DNA; Dose-Response Relationship, Drug; Flow Cyto | 1986 |
In vitro and in vivo studies of a promising antileukemic thymidine analogue, 5-hydroxymethyl-2' deoxyuridine.
Topics: Animals; Antineoplastic Agents; Blood Platelets; Cell Line; Deoxycytidine; Humans; Leukemia; Leukemi | 1986 |
Comparison of the effects of fermented and unfermented mistletoe preparations on cultured tumor cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Cells, Cultured; Fermentation; Humans; Le | 1986 |
The molecular basis for the differential sensitivity of B and T lymphocytes to growth inhibition by thymidine and 5-fluorouracil.
Topics: B-Lymphocytes; Cells, Cultured; Chromatography, Gel; Chromatography, Ion Exchange; Drug Resistance; | 1985 |
Differential sensitivity of leukemic cells to growth inhibition by deoxyadenosine and deoxycoformycin.
Topics: Acute Disease; B-Lymphocytes; Cell Line; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deox | 1985 |
Double labeling of human leukemic cells using 3H-cytarabine and monoclonal antibody against bromodeoxyuridine.
Topics: Antibodies, Monoclonal; Autoradiography; Bone Marrow; Bromodeoxyuridine; Cells, Cultured; Cytarabine | 1985 |
Double labeling and in vitro versus in vivo incorporation of bromodeoxyuridine in patients with acute nonlymphocytic leukemia.
Topics: Automation; Autoradiography; Bone Marrow Cells; Bromodeoxyuridine; Cell Cycle; Cytarabine; DNA, Neop | 1985 |
No correlation between membrane potential and increased cytosolic free Ca2+ concentration, 86Rb+ influx or subsequent [3H]-thymidine incorporation in neoplastic human B cells stimulated with antibodies to surface immunoglobulin.
Topics: Antibodies; B-Lymphocytes; Calcium; Cells, Cultured; Cytosol; Flow Cytometry; Fluorescent Antibody T | 1985 |
An evaluation of high resolution chromosome banding of hematologic cells by methotrexate synchronization and thymidine release.
Topics: Acute Disease; Chromosome Banding; Chronic Disease; Humans; Karyotyping; Leukemia; Metaphase; Methot | 1985 |
Cytotoxicity of the alkyl-linked lipoidal amine 4-aminomethyl-1-[2,3-(di-n-decyloxy)-n-propyl]-4-phenylpiperidine (CP-46,665) in cells from human tumors and leukemias.
Topics: Adjuvants, Immunologic; Cell Line; Cell Survival; Humans; Leukemia; Microscopy, Electron, Scanning; | 1985 |
Cellular pharmacology in murine and human leukemic cell lines of diaziquone (NSC 182986).
Topics: Animals; Antineoplastic Agents; Aziridines; Azirines; Benzoquinones; Carbon Radioisotopes; Cell Divi | 1985 |
Erythroid induction of K562 human leukemia cells: enhancement by purines.
Topics: Adenine; Cell Cycle; Cell Division; Cell Line; Drug Synergism; Guanine; Hemoglobins; Humans; Hypoxan | 1985 |
Modulation of 1-beta-D-arabinofuranosylcytosine metabolism by thymidine in human acute leukemia.
Topics: Acute Disease; Cytarabine; Deoxycytosine Nucleotides; DNA; Drug Interactions; Drug Therapy, Combinat | 1985 |
5-Hydroxymethyl-2'-deoxyuridine. Cytotoxicity and DNA incorporation studied by using a novel [2-14C]-derivative with normal and leukemic human hematopoietic cells.
Topics: Carbon Radioisotopes; Cell Division; Cell Line; DNA; DNA, Neoplasm; Humans; Kinetics; Leukemia; Lymp | 1985 |
[Damage to DNA by tritiated thymidine and its development in normal human (PHA-stimulated lymphocytes) and leukemic (Molt-3) lymphoblasts].
Topics: Cell Cycle; Cell Line; DNA; Dose-Response Relationship, Drug; Humans; Leukemia; Lymphocyte Activatio | 1985 |
Inhibition by ouabain of spontaneous D.N.A. synthesis in acute leukaemic leucocytes in vitro.
Topics: Adult; Aged; Child; Child, Preschool; Cyclophosphamide; DNA; DNA, Neoplasm; Female; Humans; In Vitro | 1971 |
Inhibition by ouabain of spontaneous D.N.A. synthesis in acute leukaemic leucocytes in vitro.
Topics: Acute Disease; DNA; Erythrocytes; Humans; In Vitro Techniques; Leukemia; Leukocytes; Ouabain; Rubidi | 1971 |
Isolation and characterization of a herpesvirus from leukemic guinea pigs.
Topics: Animals; Antigens, Viral; Carbon Isotopes; Centrifugation, Density Gradient; Cesium; Chlorides; Cult | 1971 |
Detection of complexes containing 70S RNA and reverse transcriptase in human leukemic plasma.
Topics: Avian Leukosis Virus; Cell-Free System; DNA, Viral; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, | 1973 |
Megakaryocyte polyploidization in acute leukaemia and preleukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Autoradiography; Blood Cell Count; Bone Marrow Cells; DNA; F | 1974 |
Organization and communication in populations of normal and leukemic hemopoietic cells.
Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Chromatography, DEAE-Cellulo | 1974 |
[Recent biochemical findings in leukemia].
Topics: Carbon Radioisotopes; Cell Transformation, Neoplastic; Chromatography, Affinity; Chromatography, DEA | 1974 |
[Nucleic acid synthesis and cytostatic drug effect in pathological lymph node cells].
Topics: Aged; Antineoplastic Agents; Dactinomycin; Depression, Chemical; DNA, Neoplasm; Hodgkin Disease; Hum | 1966 |
Studies on a new mechanism of resistance of L5178Y murine leukemia cells to cytosine arabinoside.
Topics: Animals; Chromosomes; Culture Techniques; Cytarabine; Cytosine Nucleotides; Depression, Chemical; Hy | 1968 |
[On the determination of proliferation of bone marrow cells in vitro by radioautography].
Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Child; Culture Techniques; Humans; Leukemia; Method | 1968 |
[The proliferation kinetics of normal and leukemic granulocytopoiesis].
Topics: Agranulocytosis; Autoradiography; Bone Marrow Examination; Colchicine; DNA; Hematopoiesis; Humans; K | 1969 |
Some characteristics of the proliferative activity of erythroblasts in untreated and treated acute leukaemia.
Topics: Acute Disease; Adolescent; Adult; Aged; Autoradiography; Bone Marrow Examination; DNA; Erythrocytes; | 1973 |
[Column-chromatographic enrichment of DNA-polymerase activity in leukemia].
Topics: Carbon Radioisotopes; Chromatography, DEAE-Cellulose; Chromatography, Gel; DNA Nucleotidyltransferas | 1973 |
[Sites of action of Vinca-alcaloids in protein and nucleic acid metabolism of leukemic lymphocytes in vitro. 2].
Topics: Animals; Blood Proteins; Carbon Isotopes; Cattle; Cattle Diseases; Depression, Chemical; DNA Nucleot | 1969 |
Studies of cellular proliferation in human leukemia. 3. Behavior of leukemic cells in three adults with acute leukemia given continuous infusions of 3H-thymidine for 8 or 10 days.
Topics: Acute Disease; Adult; Aged; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Nuc | 1970 |
Cellular immune reactions to human leukemia.
Topics: Antigens, Neoplasm; Bone Marrow; Bone Marrow Cells; Cell Membrane; Chromium Isotopes; Cytotoxicity T | 1972 |
Mixed leukocyte culture utilizing whole blood. A simplified technique.
Topics: Anemia, Aplastic; Blood; Cobalt Isotopes; Culture Media; Erythrocytes; Histocompatibility Testing; H | 1973 |
T and B lymphocyte membrane markers in cells from patients with leukemia and lymphoma.
Topics: Adult; Antibodies; B-Lymphocytes; Binding Sites, Antibody; Cell Membrane; Cells, Cultured; Child; Co | 1974 |
In vitro thymidine uptake by circulating leukocytes.
Topics: Adult; Biological Transport; Cells, Cultured; Hematologic Diseases; Humans; Leukemia; Leukemia, Lymp | 1974 |
Thymidine salvage pathway in normal and leukemic leukocytes with effects of ATP on enzyme control.
Topics: Adenosine Triphosphate; Carbon Isotopes; Chromatography, Paper; Cyclic AMP; Humans; Leukemia; Leukoc | 1969 |
Interferon production by human leukocytes in vitro: some biological characteristics.
Topics: Antimetabolites; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Culture Techniques; Cytarabine; Da | 1969 |
Cytogenetic studies of EB virus-positive and EB virus-negative lymphoblastoid cell lines.
Topics: Acute Disease; Autoradiography; Burkitt Lymphoma; Cell Line; Chromosome Aberrations; Chromosomes; Ch | 1971 |
Studies on the relationship of leukemia in animals and man.
Topics: Animals; Burkitt Lymphoma; Cats; Cricetinae; Cytotoxicity Tests, Immunologic; Dogs; Fluorescent Anti | 1971 |
Cell proliferation in cancer.
Topics: Acute Disease; Animals; Autoradiography; Bone Marrow Cells; Carcinoma, Hepatocellular; Carcinoma, Sq | 1968 |
Regulation of normal and leukaemic lymphocyte transformation and recirculation by sodium periodate oxidation and sodium borohydride reduction.
Topics: Animals; Borohydrides; Cell Membrane; Chromium Isotopes; Lectins; Leukemia; Liver; Lymph Nodes; Lymp | 1972 |
Superinfection with Epstein-Barr virus of human lymphoid cell lines of different origin.
Topics: Antigens, Viral; Burkitt Lymphoma; Cell Line; DNA, Viral; Herpesvirus 4, Human; Humans; Infectious M | 1973 |
Characterization of human leukemia and Burkitt lymphoma cells by their acidic nuclear protein profiles.
Topics: Acrylamides; Burkitt Lymphoma; Cell Nucleus; Cell Transformation, Neoplastic; Cells, Cultured; DNA, | 1972 |
Selective toxicity of rifamycin derivatives for leukaemic human leucocytes.
Topics: Antibiotics, Antineoplastic; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Differentiation; | 1972 |
[Study on the specific gravities of leukemic cells: comparison between the cells in the bone marrow and the peripheral blood].
Topics: Adult; Aged; Blood Cells; Bone Marrow; Bone Marrow Cells; Female; Humans; Leukemia; Leukemia, Myeloi | 1972 |
Prediction of the response of patients with acute nonlymphocytic leukemia to cytosine arabinoside (NSC-63878) therapy.
Topics: Adult; Aged; Cytarabine; Female; Humans; Kinetics; Leukemia; Leukemia, Monocytic, Acute; Leukemia, M | 1972 |
[Enzymes of thymidine and thymidylate metabolism in normal and pathological blood and bone marrow cells].
Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Chromatography, Thin Layer | 1972 |
[Proliferation of blast cells in acute leukemia].
Topics: Acute Disease; Autoradiography; Bone Marrow Cells; DNA, Neoplasm; Hematopoietic Stem Cells; Humans; | 1973 |
Factors in human serum affecting the proliferation of normal and leukemic cells.
Topics: Anemia, Aplastic; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Line; Cycloph | 1973 |
Human preleukemia. Identification of a maturation defect in vitro.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division | 1973 |
[Proliferative capacity of human leukemic bone marrow cells. Correlation between cytologic aspects, clinical evolution and therapeutic effectiveness].
Topics: Adolescent; Adult; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Transformation, Neoplastic; C | 1973 |
Asynchronisms between DNA and RNA synthesis in leukemic cells.
Topics: Blood Donors; Bone Marrow; DNA; DNA, Neoplasm; Humans; Isotope Labeling; Leukemia; Leukemia, Lymphoi | 1974 |
Inactivation of mammalian cells after disintegration of 3H or 125I in cell DNA at -196 degrees C.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cricetinae; DNA; Dose-Response Relationship, Radia | 1973 |
Proceedings: Cellular kinetics in acute leukemia.
Topics: Acute Disease; Asparaginase; Cell Division; Cell Survival; Cytarabine; DNA; Glucocorticoids; Humans; | 1972 |
The biochemist's outlook on cancer research.
Topics: Aerobiosis; Animals; Antineoplastic Agents; Biochemistry; Carbon Radioisotopes; Cell Transformation, | 1973 |
[Physicochemical properties and antileukemic activity of crystalline L-asparaginase from Escherichia coli].
Topics: Antineoplastic Agents; Asparaginase; Burkitt Lymphoma; Cell Line; Cells, Cultured; Chemical Phenomen | 1974 |
The B-lymphocyte nature of the hairy cell of leukaemic reticuloendotheliosis.
Topics: Animals; B-Lymphocytes; Binding Sites; Candida; Cell Adhesion; Cell Membrane; Cells, Cultured; Compl | 1974 |
New progressive factors affecting response and survival in adult acute leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Antibody Formation; Antigens, Neoplasm; Bone Marrow; | 1974 |
Cell proliferation in the "preleukaemic" phase of acute leukaemia. A cytophotometric and autoradiographic study.
Topics: Acute Disease; Adolescent; Anemia, Sideroblastic; Autoradiography; Blood Transfusion; Bone Marrow; B | 1972 |
The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases.
Topics: Adenosine; Animals; Antigen-Antibody Complex; Antigens; Arthritis, Rheumatoid; Cattle; DNA; DNA, Sin | 1973 |
[Relationship between parameters of cell proliferation in acute human leukemia and the effect on those cells of antileukemic drugs in vivo].
Topics: Acute Disease; Animals; Autoradiography; Blood Transfusion, Autologous; Bone Marrow; Bone Marrow Cel | 1972 |
A covalently linked DNA-RNA molecule from human leukemia cells.
Topics: Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Cesium; DNA, Neoplasm; Humans; Leukemi | 1973 |
[Radiation-induced adsorption of 3 H-thymidine on leukoma cells].
Topics: Animals; Cell Membrane Permeability; Leukemia; Leukemia, Experimental; Neoplasm Transplantation; Rat | 1973 |
[Leukemias. Fundamental data. Cell kinetics in acute leukemias].
Topics: Acute Disease; Cell Transformation, Neoplastic; Infusions, Parenteral; Injections; Kinetics; Leukemi | 1973 |
The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients.
Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lectins; Leukemia; Lymph | 1973 |
Hemoglobin synthesis in murine virus-induced leukemic cells in vitro. 3. Effects of 5-bromo-2'-deoxyuridine, dimethylformamide and dimethylsulfoxide.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cells, Cultured; Clone Cells; Culture Media; Dimet | 1973 |
[Cytokinetics of human acute leukemia].
Topics: Acute Disease; Cell Division; Humans; Kinetics; Leukemia; Thymidine; Tritium | 1973 |
An analysis of the relationship of leukemic cell kinetics to chemotherapy.
Topics: Bone Marrow; Bone Marrow Cells; Cytarabine; Daunorubicin; DNA; Drug Therapy, Combination; Hematopoie | 1973 |
[Therapy of acute leukemias].
Topics: Acute Disease; Adult; Antineoplastic Agents; Asparaginase; DNA, Neoplasm; Humans; Immunosuppression | 1973 |
[Repair synthesis of DNA in normal and leukemic lymphocytes damaged by an alkylating agent. Inhibition of repair synthesis by caffeine. Preliminary report].
Topics: Alkylating Agents; Caffeine; Cells, Cultured; DNA; DNA Repair; Humans; Hydroxyurea; Leukemia; Lympho | 1974 |
Effect of cytostatic drugs on the kinetics of leukemic blast cells in man.
Topics: Antineoplastic Agents; Asparaginase; Bone Marrow; Bone Marrow Cells; Cell Division; Cytarabine; Daun | 1974 |
Chemotherapy after synchronization of tumor cells.
Topics: Animals; Bronchial Neoplasms; Carbon Radioisotopes; Carcinoma; Carcinoma, Ehrlich Tumor; Cell Divisi | 1974 |
Effects of 5-bromo-2'-deoxyuridine (BUdR) on in vitro colony formation in cultures of mouse bone marrow cells.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Bromodeoxyuridine; Cell Aggregation; Cells, Cultured; Centr | 1974 |
Sensitivity of different target cells to the killing action of peripheral lymphocytes stimulated by autologous lymphoblastoid cell lines.
Topics: Blood Donors; Burkitt Lymphoma; Cell Line; Chromium Radioisotopes; Culture Media; Cytotoxicity Tests | 1974 |
Chromatin clumping in mature leukocytes: a hitherto unrecognized abnormality.
Topics: Aged; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Movement; Cell Nucleus; Chromium Isotopes; | 1970 |
The cytology, distribution and function of the neoplastic cells in leukaemic reticuloendotheliosis.
Topics: Adult; Blood Cell Count; Bone Marrow; Cell Nucleus; Cell Transformation, Neoplastic; Cytoplasm; Huma | 1970 |
Studies on cellular proliferation in human leukemia. VII. Cytokinetic behavior of neoplastic cells in a patient with reticulum cell sarcoma in a leukemic phase.
Topics: Adult; Autoradiography; Biopsy; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Differentiatio | 1971 |
Growth-retarding mechanisms against lymphatic tumours. Search in mice and men.
Topics: Animals; Antigens; Antigens, Bacterial; Antigens, Neoplasm; Autoradiography; Child; Child, Preschool | 1971 |
Macroglobulinemia Waldenström with miliary lunginfiltrations and terminal plasmacell-leukemia. (Chlorambuci induced clinical remission despite autoradiographically persistant DNA- and RNA-synthesis).
Topics: Aged; Autoradiography; Biopsy; Bone Marrow Examination; Chlorambucil; DNA; Female; Humans; Immunoele | 1966 |
Cell proliferation in leukemia during relapse and remission. I. DNA and RNA synthesis of leukemic cells in the bone marrow in vitro.
Topics: Bone Marrow; Bone Marrow Cells; Cell Division; DNA; Humans; In Vitro Techniques; Leukemia; RNA; Thym | 1966 |
Division of leukocytes already in DNA synthesis from patients with acute leukemia and infectious mononucleosis.
Topics: Adult; Aged; Cell Division; Child; Child, Preschool; DNA; Humans; Infectious Mononucleosis; Leukemia | 1967 |
Proliferative activity of the cells of acute leukaemia in relapse and in steady state.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Humans; Leukemia; Mitosis; Nucleic Acids; Thymidine; Tritium | 1967 |
Maturation of leukaemic blast cells.
Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; DNA; Humans; Leukemia; Leukemia, Lym | 1971 |
[Cytokinetic study on an aleukemic acute myeloic leukemia].
Topics: Adult; Autoradiography; Blood Cell Count; Bone Marrow Cells; Bone Marrow Examination; Hematopoiesis; | 1971 |
Blastic transformation of lymphocytes in some proliferative diseases of the leukocytic system.
Topics: Carbon Isotopes; Cells, Cultured; Hodgkin Disease; Humans; Immune Sera; Lectins; Leukemia; Lymphocyt | 1971 |
Bovine trypanosomiasis and lymphocytosis parallel studies.
Topics: Animals; Antibodies; Antigens; Cattle; Cattle Diseases; Cells, Cultured; Immunodiffusion; Leukemia; | 1970 |
[Autoradiographic and cytophotometric studies on hematopoiesis in primarily refractory and sideroachrestic anemia].
Topics: Anemia; Anemia, Macrocytic; Autoradiography; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Diplo | 1972 |
Studies of inhibition of tumour cell DNA synthesis by immune cells in Gross virus induced leukemia.
Topics: Adjuvants, Immunologic; AKR murine leukemia virus; Animals; Antigens, Neoplasm; Cells, Cultured; DNA | 1972 |
Use of cell separation at 1 g for cytokinetic studies in spontaneous AKR leukemia.
Topics: Animals; Autoradiography; Cell Fractionation; Centrifugation, Density Gradient; Disease Models, Anim | 1972 |
Evaluation of a new glutathione-oxidizing reagent for studies of nucleated mammalian cells.
Topics: Amides; Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Movement; Cell Survival; Cells, Cultured; | 1971 |
A micro-system for screening anti-leukemic drugs utilizing human whole blood.
Topics: Adult; Aged; Cytarabine; DNA; Evaluation Studies as Topic; Female; Humans; Infant; Leukemia; Leukocy | 1971 |
Inhibition by lymphocyte nuclei of DNA and RNA synthesis in stimulated lymphocytes and leukaemic cells.
Topics: Cell Fractionation; Cell Nucleus; Chromatin; DNA; Humans; Lectins; Leukemia; Lymphocyte Activation; | 1971 |
Anticancer effects of propanals: comparison between human and animal tumor systems.
Topics: Aldehydes; Animals; Antineoplastic Agents; Carbohydrate Metabolism; Carbon Isotopes; DNA, Neoplasm; | 1971 |
[In vitro proliferation of leukemic blast cells and response to daunorubidomycin-cytosine arabinoside].
Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Count; Cytarabine; Daunorubicin; Humans; Leuke | 1971 |
Proliferative activity of blast cells in leukemia and myelofibrosis. Morphological differences between proliferating and non-proliferating blast cells.
Topics: Adolescent; Adult; Aged; Autoradiography; Blood Cells; Bone Marrow; Bone Marrow Cells; Humans; Leuke | 1965 |
Dihydrofolate reductase activity and deoxynucleoside incorporation into DNA of human leukocytes. Relation to methotrexate administration.
Topics: Adolescent; Adult; Child; Child, Preschool; Deoxyuridine; DNA; Female; Humans; Leukemia; Leukemia, L | 1967 |
Chromosomal changes of similar nature in seven established cell lines derived from the peripheral blood of patients with leukemia.
Topics: Autoradiography; Chromosomes; Culture Techniques; Cytogenetics; DNA; Female; Humans; Karyotyping; Le | 1967 |
Possible defect in RNA metabolism in leukemic cells.
Topics: Acute Disease; Adult; Bone Marrow; Bone Marrow Cells; Chronic Disease; Humans; Leukemia; Leukemia, L | 1968 |
Proliferative activity of leukaemic cells at various stages of acute leukaemia of childhood.
Topics: Aneuploidy; Blood Cell Count; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Chi | 1968 |
Drug effect in acute leukemia.
Topics: Adolescent; Bone Marrow; Bone Marrow Cells; Child; Child, Preschool; Cytarabine; DNA, Neoplasm; Huma | 1969 |
Deoxyribonucleic acid (DNA) repair replication of ultraviolet (UV) irradiated normal and leukemic leukocytes.
Topics: Animals; Autoradiography; Blood; DNA; Humans; Leukemia; Leukemia, Lymphoid; Leukemia, Myeloid; Leuko | 1969 |
The leukemic and mononucleosis cell. 3. DNA synthesis.
Topics: Adolescent; Adult; Aged; Autoradiography; Carbon Isotopes; Child; Child, Preschool; DNA; DNA, Neopla | 1969 |
Treatment of leukemia with large doses of methotrexate and folinic acid: clinical-biochemical correlates.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Deoxyuridine; DNA, Neoplasm; Female; Folic Acid; H | 1969 |
Proliferation and differentiation of hematopoietic cells in hematologic disorders. 3. In vivo radioautographic study of leukemia including erythroleukemia.
Topics: Adult; Female; Hematopoiesis; Humans; Injections, Intravenous; Leukemia; Leukemia, Erythroblastic, A | 1968 |
[Determination of asparagine synthetase in leukemic cells as indicator of successful enzyme therapy in hemoblastoses].
Topics: Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Humans; In Vitro Techn | 1970 |
[Radioautographic and Feulgen-photometric studies on DNA-synthesis in leukemic cells].
Topics: Adolescent; Adult; Aged; Autoradiography; DNA; Female; Humans; In Vitro Techniques; Leukemia; Leukem | 1971 |
[Autoradiographic and enzyme-chemical studies of DNA synthesis in leukemia cells. I. Correlation of thymidine-kinase and 3 H-thymidine labelling index].
Topics: Acute Disease; Adolescent; Adult; Aged; Autoradiography; Bone Marrow; Bone Marrow Cells; Chronic Dis | 1970 |
The acute leukemic cell. IV. DNA synthesis in peripheral blood and bone marrow.
Topics: Acute Disease; Adult; Aged; Autoradiography; Blood Cells; Bone Marrow; Bone Marrow Cells; DNA Replic | 1971 |
In-vitro activation of lymphocytes from patients with malignant diseases. II. Studies on the behaviour of stimulated lymphocytes from patients with leukemia.
Topics: Analysis of Variance; Asparaginase; Cell Survival; Cells, Cultured; Chronic Disease; Filtration; Hum | 1971 |
[Radioautographic study of the proliferation of leukemic cells, using tritiated thymidine].
Topics: Autoradiography; Blood Cells; Bone Marrow; Bone Marrow Cells; Cell Division; Humans; Leukemia; Leuko | 1969 |
Possible significance of nonproliferating leukemic cells.
Topics: Acute Disease; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Child, Prescho | 1969 |
Effect of anti-leukemic drugs on cell cycle of human leukemic blast cells in vivo.
Topics: Adult; Bone Marrow; Bone Marrow Cells; Cell Transformation, Neoplastic; DNA, Neoplasm; Humans; Leuke | 1969 |
[Intensity of DNA and cytoplasmic protein synthesis in leukocytic elements in acute leukemia].
Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Cytoplasm; DNA; Humans; Leukemia; Methionine; Prote | 1969 |
Quantitative cytochemical studies of deoxyribonucleic acid in hemopoietic cells. 3. DNA synthesis and proliferation of acute leukemia cells.
Topics: Acute Disease; Adolescent; Adult; Autoradiography; Child; DNA; Female; Histocytochemistry; Humans; L | 1969 |
The rationale of the chemotherapeutic regimes relative to present knowledge of cell and population kinetics.
Topics: Animals; Cell Differentiation; Cell Division; DNA; Humans; Kinetics; Leukemia; Leukemia L1210; Leuke | 1970 |
Leukocytes as carriers in the transmission of bovine leukemia: certain morphologic and functional characteristics of cultured leukocytes from normal and leukemic cattle.
Topics: Animals; Blood; Carrier State; Cattle; Cattle Diseases; Cell Nucleus; Culture Techniques; DNA; Glass | 1970 |
Leukocytes as carriers in the transmission of bovine leukemia: invasion of the digestive tract of the newborn by ingested, cultured, leukocytes.
Topics: Animals; Animals, Newborn; Carrier State; Cattle; Cattle Diseases; Culture Techniques; Digestive Sys | 1970 |
Proliferative capacity of leukemic cells in AKR leukemia.
Topics: Animals; Autoradiography; Cell Membrane; Centrifugation, Density Gradient; Culture Techniques; DNA, | 1970 |
Lymphocyte stimulation: the effect of ouabain on nucleic acid and protein synthesis.
Topics: Animals; Autoradiography; Culture Techniques; DNA; Hydrocortisone; Lectins; Leucine; Leukemia; Lymph | 1970 |
Sensitivity to L-asparaginase and amino acid metabolism.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; | 1970 |
Mixed culture of human foetal and adult cells.
Topics: Acute Disease; Chronic Disease; Culture Techniques; Cytotoxicity Tests, Immunologic; DNA; DNA, Neopl | 1971 |
Hodgkin's disease terminating in acute lymphosarcoma cell leukemia. A metabolic study.
Topics: Acetates; Acute Disease; Adult; Antineoplastic Agents; Carbon Isotopes; Diagnosis, Differential; DNA | 1971 |
Blast cell proliferation in a child with untreated acute leukaemia: results of a preliminary study using tritiated thymidine for pulse-labelling in vivo.
Topics: Acute Disease; Bone Marrow; Bone Marrow Cells; Cell Division; Child; Female; Humans; Leukemia; Thymi | 1967 |
[Blood concentration of cells appearing as blasts and cells incorporating tritiated thymidine in patients having lymphosarcoma or acute or chronic lymphoid leukemia].
Topics: Blood Cells; Humans; Leukemia; Lymphoma, Non-Hodgkin; Thymidine; Tritium | 1967 |
Thymidine kinase activity in the human bone marrow from various blood diseases.
Topics: Anemia; Bone Marrow; Bone Marrow Cells; Chromatography, Paper; Humans; Leukemia; Thymidine; Thymidin | 1968 |
Correlation of stimultaneous 3H and 14C autoradiography with gas counting.
Topics: Animals; Autoradiography; Carbon Isotopes; Gases; Leukemia; Liver; Methods; Mice; Thymidine; Tritium | 1968 |
[Studies on kinetics of human leukocytes in vivo with 3H-thymidine radioautography, (I) neutrophils].
Topics: Adult; Aged; Autoradiography; Blood Cell Count; Bone Marrow; Bone Marrow Cells; DNA; Female; Hematop | 1968 |
Proliferation and differentiation of hematopoietic cells in hematologic disorders. II. In vitro radioautographic study of leukemic cells.
Topics: Adult; Aged; Culture Techniques; Female; Hematopoiesis; Humans; Leucine; Leukemia; Leukemia, Lymphoi | 1968 |
[Current data on human tumor kinetics].
Topics: Animals; Ascites; Biopsy; Humans; Kinetics; Leukemia; Lung Neoplasms; Mammary Neoplasms, Experimenta | 1969 |
Correction for threshold error in the determination of generation times by the grain-count halving method.
Topics: Autoradiography; Bone Marrow; Bone Marrow Cells; Humans; Leukemia; Mathematics; Mitosis; Models, The | 1969 |
In vitro DNA labeling of bone marrow and leukemic blood leukocytes with tritiated thymidine. I. Physical and chemical factors which affect autoradiographic cell labeling.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; DNA; Dogs; In Vitro Techniques; Leukemia; | 1965 |
[Evaluation of DNA and RNA metabolism at the chromosome level in human blood cells by means of an autoradiographic method].
Topics: Autoradiography; Blood Cells; Bone Marrow; Bone Marrow Cells; Chromosomes; DNA; Humans; Leukemia; Ne | 1964 |
[Recent acquisitions on the synthesis of DNA in normal and pathological leukocytes].
Topics: Animals; Cell Division; Clinical Enzyme Tests; DNA; Hodgkin Disease; Humans; In Vitro Techniques; Le | 1965 |
Studies on myelocytic cell turnover in bone marrow and blood.
Topics: Autoradiography; Bacterial Infections; Bone Marrow; Bone Marrow Cells; Hematopoiesis; Humans; Isotop | 1963 |
Limitations and goals in cancer chemotherapy.
Topics: Antineoplastic Agents; Humans; Leukemia; Nitrogen Mustard Compounds; Thymidine | 1966 |
In vitro DNA labeling of bone marrow and leukemic blood leukocytes with tritiated thymidine. II. H3 thymidine biochemistry in vitro.
Topics: Animals; Antineoplastic Agents; Autoradiography; Bone Marrow; Bone Marrow Cells; Chromatography, Pap | 1966 |
[Study of cell division by radioautography in acute leukemia in children. 2. Increase of leukemic cells and erythroblasts in acute leukemia in children].
Topics: Adolescent; Autoradiography; Child; Child, Preschool; Erythrocyte Count; Female; Humans; Leukemia; L | 1966 |