thymidine has been researched along with Leukemia L5178 in 20 studies
Leukemia L5178: An experimental lymphocytic leukemia of mice.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mouse lymphoma L5178Y Tk(+/-) assay is broadly used in toxicology to assess genotoxicity because of its known sensitivity to genotoxicants that act through a variety of mechanisms, which may include epigenetic DNA methylation." | 1.39 | Can the L5178Y Tk+/- mouse lymphoma assay detect epigenetic silencing? ( Cheng, TF; Muldoon-Jacobs, K; Patton, GW, 2013) |
| "Chromosome abnormalities were present in cells from 12% (7/60) of the UC colonies, but there was no apparent relationship between colony diameter and the presence of chromosomal abnormalities." | 1.28 | Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures. ( Blazak, WF; Caspary, WJ; Los, FJ; Rudd, CJ, 1989) |
| " Dose-response curves were produced for these compounds." | 1.26 | Comparative mutagenicity of hydrazine and 3 methylated derivatives in L5178Y mouse lymphoma cells. ( Back, KC; Rogers, AM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (80.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cheng, TF | 1 |
| Patton, GW | 1 |
| Muldoon-Jacobs, K | 1 |
| Lloyd, M | 1 |
| Kidd, D | 1 |
| Leyhausen, G | 1 |
| Seibert, G | 1 |
| Maidhof, A | 2 |
| Müller, WE | 2 |
| Torrent-Quetglas, M | 2 |
| Grau-Oliete, MR | 1 |
| Rivera-Fillat, MP | 1 |
| Moore-Brown, MM | 1 |
| Clive, D | 1 |
| Howard, BE | 1 |
| Batson, AG | 1 |
| Johnson, KO | 1 |
| Sawada, S | 1 |
| Enomoto, T | 1 |
| Kapp, LN | 1 |
| Rogers, AM | 2 |
| Back, KC | 1 |
| Hill, R | 1 |
| Lehmann, AR | 1 |
| Arlett, CF | 1 |
| Burns, VW | 1 |
| Wlodek, D | 1 |
| Olive, PL | 1 |
| Wang, LM | 1 |
| White, JC | 1 |
| Capizzi, RL | 1 |
| Amacher, DE | 1 |
| Turner, GN | 1 |
| Moore, MM | 1 |
| Applegate, ML | 1 |
| Hozier, JC | 1 |
| Blazak, WF | 1 |
| Los, FJ | 1 |
| Rudd, CJ | 1 |
| Caspary, WJ | 2 |
| Kapiszewska, M | 1 |
| Lange, CS | 1 |
| Allen, LB | 1 |
| Schröder, HC | 1 |
| Löbering, HG | 1 |
| Oberly, TJ | 1 |
| Bewsey, BJ | 1 |
| Probst, GS | 1 |
| Myhr, B | 1 |
| Bowers, L | 1 |
| McGregor, D | 1 |
| Riach, C | 1 |
| Brown, A | 1 |
| Sawecka, J | 1 |
| Golos, B | 1 |
| Malec, J | 1 |
| Meldrum, JB | 1 |
| Gupta, VS | 1 |
| Lowes, NR | 1 |
| Paterson, AR | 1 |
20 other studies available for thymidine and Leukemia L5178
| Article | Year |
|---|---|
Can the L5178Y Tk+/- mouse lymphoma assay detect epigenetic silencing?
Topics: Aminopterin; Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Cell Survival; Clone Cells; | 2013 |
The mouse lymphoma assay.
Topics: Animals; Cell Line, Tumor; Cell Survival; Genetic Loci; Leukemia L5178; Lymphoma; Mice; Mutagenicity | 2012 |
Differential stimulation of lymphocyte cell growth in vitro by cephalosporins.
Topics: Animals; Binding Sites; Cell Line; Cephalosporins; Concanavalin A; DNA-Directed DNA Polymerase; Leuk | 1984 |
Uptake of thymidine by plasma membrane vesicles of L5178Y murine leukemic cells.
Topics: Animals; Binding Sites; Biological Transport; Cell Membrane; Kinetics; Leukemia L5178; Leukemia, Exp | 1984 |
The utilization of trifluorothymidine (TFT) to select for thymidine kinase-deficient (TK-/-) mutants from L5178Y/TK+/- mouse lymphoma cells.
Topics: Animals; Bromodeoxyuridine; Cell Separation; Dose-Response Relationship, Drug; Leukemia L5178; Leuke | 1981 |
Relationship between DNA chain growth termination and replicon sizes in gamma-irradiated mouse cells.
Topics: Animals; Autoradiography; Cells, Cultured; DNA, Neoplasm; Gamma Rays; Leukemia L5178; Leukemia, Expe | 1982 |
Comparative mutagenicity of hydrazine and 3 methylated derivatives in L5178Y mouse lymphoma cells.
Topics: Animals; Hydrazines; Leukemia L5178; Mice; Mutagenicity Tests; Mutagens; Thymidine | 1981 |
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cytarabine; Drug Resistance; Ethidium; Ethyl Methanesulfo | 1980 |
Neutral filter elution detects differences in chromatin organization which can influence cellular radiosensitivity.
Topics: Animals; Carbon Radioisotopes; Cell Line; CHO Cells; Chromatin; Cricetinae; DNA; DNA Damage; Dose-Re | 1992 |
The effect of ara-C-induced inhibition of DNA synthesis on its cellular pharmacology.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Cytarabine; Depression, Chemical; DNA-Directed DNA P | 1990 |
The mutagenicity of 5-azacytidine and other inhibitors of replicative DNA synthesis in the L5178Y mouse lymphoma cell.
Topics: Animals; Aphidicolin; Azacitidine; Cell Line; Cytidine; Diterpenes; Drug Resistance; Leukemia L5178; | 1987 |
Do trifluorothymidine-resistant mutants of L5178Y mouse lymphoma cells re-express thymidine kinase activity following 5-azacytidine treatment?
Topics: Animals; Azacitidine; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Thymi | 1988 |
Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures.
Topics: Animals; Chromosome Aberrations; Dimethyl Sulfoxide; Hycanthone; Leukemia L5178; Leukemia, Experimen | 1989 |
The effect of hypothermic treatment on the repair or expression of X-ray damage measured in split dose experiments on L5178Y-S cells.
Topics: Animals; Cell Cycle; Cell Survival; DNA Repair; DNA, Neoplasm; Filtration; Leukemia L5178; Leukemia, | 1989 |
Cytostatic and antiherpesvirus type 1 and 2 activities of 1-beta-D-arabinofuranosylthymine (ara T) prodrugs.
Topics: Animals; Antineoplastic Agents; Antiviral Agents; Arabinonucleosides; Cell Line; Leukemia L5178; Mic | 1987 |
Thymidine kinase activity and trifluorothymidine resistance of spontaneous and mutagen-induced L5178Y cells in RPMI 1640 medium.
Topics: Animals; Cell Line; Culture Media; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Methylch | 1986 |
Mutagenic activity of fluorides in mouse lymphoma cells.
Topics: Animals; Biotransformation; Fluorides; Leukemia L5178; Male; Mice; Microsomes, Liver; Mutagenicity T | 1987 |
Mechanism of unbalanced growth-induced cell damage. II. A probable relationship between unbalanced growth, DNA breakage and cell death.
Topics: Animals; Cell Division; Cell Survival; DNA Damage; DNA Replication; Endodeoxyribonucleases; Hydroxyu | 1986 |
Oil-stop method as an alternative to filtration for transport studies on plasma membrane vesicles. A preliminary report.
Topics: Animals; Biological Transport; Cell Fractionation; Cell Membrane; Dibutyl Phthalate; Diethylhexyl Ph | 1985 |
Toxicologic and antitumor studies on 5-hydroxymethyldeoxyuridine.
Topics: Animals; Antineoplastic Agents; Body Weight; Humans; Intestine, Small; Leukemia L1210; Leukemia L517 | 1985 |