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thymidine and Leukemia, Promyelocytic, Acute

thymidine has been researched along with Leukemia, Promyelocytic, Acute in 40 studies

Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.

Research Excerpts

ExcerptRelevanceReference
"It is uncertain if acute lymphoblastic leukemia (ALL) cells expressing myeloid makers can respond to granulocyte colony-stimulating factor (G-CSF) and granulocyte macrophage colony-stimulating factor (GM-CSF)."2.68Heterogeneous effects of G-CSF and GM-CSF on cell growth and ara-C cytotoxicity in childhood leukemias which express myeloid markers. ( Cao, DC; Higashigawa, M; Hori, H; Ido, M; Kawasaki, H; Komada, Y; Kuwabara, H; Ohkubo, T; Sakurai, M, 1996)
"The lignans and genistein were strongly suppressive against incorporations of [3H]thymidine, [3H]uridine, and [3H]leucine into HL-60 cells."1.29Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. ( Gotoh, M; Hirano, T; Oka, K, 1994)
"Hydroxyl radicals were generated by a Fenton reaction, involving an ADP-Fe2+ (or ATP-Fe2+) complex and H2O2."1.29Induction of granulocytic maturation in HL-60 human leukemia cells by free radicals: a hypothesis of cell differentiation involving hydroxyl radicals. ( Bene, L; Nagy, K; Pásti, G; Zs-Nagy, I, 1993)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19907 (17.50)18.7374
1990's29 (72.50)18.2507
2000's3 (7.50)29.6817
2010's1 (2.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rho, SB1
Choi, K1
Park, K1
Lee, JH1
Stervbo, U1
Vang, O1
Bonnesen, C1
Yamaji, Y2
Shiotani, T2
Nakamura, H2
Hata, Y1
Hashimoto, Y2
Nagai, M1
Fujita, J2
Takahara, J1
Fraser, DJ1
Brandt, TL1
Kroll, DJ1
Jones, EW1
Manning, R1
Lok, CN1
Chan, KF1
Loh, TT1
Egan, MG1
Sirlin, S1
Rumberger, BG1
Garrow, TA1
Shane, B1
Sirotnak, FM1
Ryves, WJ1
Dimitrijevic, S1
Gordge, PC1
Evans, FJ1
Tanaka, Y1
Yoshihara, K1
Tsuyuki, M1
Kamiya, T1
Defacque, H1
Commes, T1
Sevilla, C1
Rochette-Egly, C1
Marti, J1
Hirano, T1
Gotoh, M1
Oka, K1
Pérez-Sala, D1
Mollinedo, F1
Nagy, K1
Pásti, G1
Bene, L1
Zs-Nagy, I1
Nishiguchi, Y1
Hibasami, H1
Komada, Y2
Sakurai, M2
Nakashima, K1
Norman, AW1
Bouillon, R1
Farach-Carson, MC1
Bishop, JE1
Zhou, LX1
Nemere, I1
Zhao, J1
Muralidharan, KR1
Okamura, WH1
Berczi, A1
Barabas, K1
Sizensky, JA1
Faulk, WP1
Miyazaki, Y1
Katamine, S1
Kohno, T1
Moriuchi, R1
Miyamoto, T1
Tomonaga, M1
Higashigawa, M1
Kuwabara, H1
Cao, DC1
Hori, H1
Ohkubo, T1
Kawasaki, H1
Ido, M1
Katayama, N1
Kita, K1
Kawakami, K1
Mitani, H1
Sugawara, T1
Mizuno, S1
Yonezawa, A1
Nishii, K1
Miwa, H1
Wada, H1
Minami, N1
Shiku, H1
Matsuhisa, T1
Pratsinis, H1
Haroutounian, SA1
Grant, S1
Jarvis, WD1
Swerdlow, PS1
Turner, AJ1
Traylor, RS1
Wallace, HJ1
Lin, PS1
Pettit, GR1
Gewirtz, DA1
Solary, E1
Bertrand, R1
Jenkins, J1
Pommier, Y1
Vassiliadis, S1
Kyrpides, N1
Papamatheakis, J1
Paulin-Levasseur, M1
Julien, M1
Sakashita, A2
Nakamaki, T2
Tsuruoka, N2
Honma, Y2
Hozumi, M2
Sur, P1
Matsuo, Y1
Otani, T1
Minowada, J1
Barrera, G1
Di Mauro, C1
Muraca, R1
Ferrero, D1
Cavalli, G1
Fazio, VM1
Paradisi, L1
Dianzani, MU1
Sokoloski, JA2
Sartorelli, AC2
Kafka, M1
Dvilansky, A1
Nathan, I1
Ishioka, C1
Kanamaru, R1
Konishi, Y1
Ishikawa, A1
Shibata, H1
Wakui, A1
Murao, S1
Collart, F1
Huberman, E1
Ross, DD1
Chen, SR1
Cuddy, DP1
Sano, M1
Hino, K1
Suzuki, K1
Tomoyasu, S1
Tanizawa, A3
Kubota, M3
Takimoto, T3
Kito, T2
Akiyama, Y3
Kiriyama, Y2
Mikawa, H3
Hashimoto, H1
Shimizu, T1
Kitoh, T1
Roberts, JR1
Rowinsky, EK1
Donehower, RC1
Robertson, J1
Allison, DC1
Futami, H1
Yamauchi, N1
Bungo, M1
Tanaka, T1
Irino, S1
Beardsley, GP1

Reviews

1 review available for thymidine and Leukemia, Promyelocytic, Acute

ArticleYear
Reciprocal alterations of enzymic phenotype of purine and pyrimidine metabolism in induced differentiation of leukemia cells.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Cell Cycle; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; GMP Reductase; Humans; IMP Dehydrog

1994

Trials

1 trial available for thymidine and Leukemia, Promyelocytic, Acute

ArticleYear
Heterogeneous effects of G-CSF and GM-CSF on cell growth and ara-C cytotoxicity in childhood leukemias which express myeloid markers.
    Leukemia & lymphoma, 1996, Volume: 22, Issue:3-4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; C

1996

Other Studies

38 other studies available for thymidine and Leukemia, Promyelocytic, Acute

ArticleYear
Inhibition of angiogenesis by the BTB domain of promyelocytic leukemia zinc finger protein.
    Cancer letters, 2010, Aug-01, Volume: 294, Issue:1

    Topics: Animals; Cell Cycle; Cell Movement; Chickens; Chorioallantoic Membrane; Cloning, Molecular; Cyclin A

2010
Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells.
    Cell proliferation, 2006, Volume: 39, Issue:6

    Topics: Annexin A5; Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Nucleus

2006
Topoisomerase II alpha promoter trans-activation early in monocytic differentiation of HL-60 human leukemia cells.
    Molecular pharmacology, 1995, Volume: 47, Issue:4

    Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; DNA Topoisomerases, Type II; Genes, Re

1995
Cytotoxic effects of membrane-active agents in human leukaemia cell lines.
    Biochemical Society transactions, 1995, Volume: 23, Issue:1

    Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Culture Media, Serum-Free; Dibucaine

1995
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells.
    FEBS letters, 1995, May-29, Volume: 365, Issue:2-3

    Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplas

1995
Rapid decline in folylpolyglutamate synthetase activity and gene expression during maturation of HL-60 cells. Nature of the effect, impact on folate compound polyglutamate pools, and evidence for programmed down-regulation during maturation.
    The Journal of biological chemistry, 1995, Mar-10, Volume: 270, Issue:10

    Topics: Blotting, Northern; Cell Division; Cell Line; Dimethyl Sulfoxide; gamma-Glutamyl Hydrolase; Gene Exp

1995
HL-60 cell differentiation induced by phorbol- and 12-deoxyphorbol-esters.
    Carcinogenesis, 1994, Volume: 15, Issue:11

    Topics: Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Phorbol Esters; Protein Kinase C; Tetr

1994
Apoptosis induced by adenosine in human leukemia HL-60 cells.
    Experimental cell research, 1994, Volume: 213, Issue:1

    Topics: Adenine Nucleotides; Adenosine; Apoptosis; Cell Line; Coformycin; Deoxyadenosines; Deoxyguanosine; D

1994
Synergistic differentiation of U937 cells by all-trans retinoic acid and 1 alpha, 25-dihydroxyvitamin D3 is associated with the expression of retinoid X receptor alpha.
    Biochemical and biophysical research communications, 1994, Aug-30, Volume: 203, Issue:1

    Topics: Animals; Blotting, Western; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus

1994
Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells.
    Life sciences, 1994, Volume: 55, Issue:13

    Topics: Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Flavonoids; Humans; Leucine;

1994
Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells.
    Biochemical and biophysical research communications, 1994, Mar-30, Volume: 199, Issue:3

    Topics: Apoptosis; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Humans; Kinetics; Leu

1994
Induction of granulocytic maturation in HL-60 human leukemia cells by free radicals: a hypothesis of cell differentiation involving hydroxyl radicals.
    Free radical research communications, 1993, Volume: 19, Issue:1

    Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA Replication; Flow Cytometry;

1993
Human promyelocytic cell line HL60 has the specific binding sites for prolactin and its ornithine decarboxylase, DNA synthesis and cellular proliferation are induced by prolactin.
    Leukemia research, 1993, Volume: 17, Issue:8

    Topics: Binding Sites; Carbon Radioisotopes; Cell Division; DNA Replication; DNA, Neoplasm; Dose-Response Re

1993
Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: Animals; Bone and Bones; Calcitriol; Calcium; Cell Division; Cell Nucleus; Cells, Cultured; Chickens

1993
Adriamycin conjugates of human transferrin bind transferrin receptors and kill K562 and HL60 cells.
    Archives of biochemistry and biophysics, 1993, Volume: 300, Issue:1

    Topics: Cell Survival; DNA Replication; Doxorubicin; Humans; Iodine Radioisotopes; Kinetics; Leukemia, Myelo

1993
fgr proto-oncogene is expressed during terminal granulocytic differentiation of human promyelocytic HL60 cells.
    Experimental hematology, 1993, Volume: 21, Issue:2

    Topics: Cell Transformation, Neoplastic; Dimethyl Sulfoxide; DNA, Neoplasm; Gene Expression Regulation, Neop

1993
Granulocyte colony-stimulating factor and its receptor in acute promyelocytic leukemia.
    American journal of hematology, 1998, Volume: 58, Issue:1

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorescent Antibody Technique; Granu

1998
Terminal differentiation of human promyelocytic leukaemia cells, HL-60, during the G1 period.
    Cell biology international, 2001, Volume: 25, Issue:2

    Topics: Calcitriol; Cell Differentiation; DNA, Neoplasm; G1 Phase; HL-60 Cells; Humans; Hydroxyurea; Leukemi

2001
Synthesis and antioxidant activity of 3-substituted guaiazulene derivatives.
    Natural product letters, 2002, Volume: 16, Issue:3

    Topics: alpha-Tocopherol; Antineoplastic Agents; Antioxidants; Azulenes; Catalysis; Drug Screening Assays, A

2002
Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA.
    Cancer research, 1992, Nov-15, Volume: 52, Issue:22

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apopt

1992
Radiolabeling of DNA can induce its fragmentation in HL-60 human promyelocytic leukemic cells.
    Experimental cell research, 1992, Volume: 203, Issue:2

    Topics: Apoptosis; Cell Division; DNA Damage; DNA, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Thymidi

1992
The role of IL-4 in human myeloid leukemia: stimulation of RNA synthesis and transduction of differentiation signals through an IL-4 receptor leads to functional and HLA positive HL-60 cells.
    Leukemia & lymphoma, 1992, Volume: 7, Issue:3

    Topics: Cell Differentiation; Cell Division; Cellular Senescence; DNA, Neoplasm; Histocompatibility Antigens

1992
Expression of intermediate filament proteins in TPA-induced MPC-11 and HL-60 cells.
    Experimental cell research, 1992, Volume: 199, Issue:2

    Topics: Animals; Blotting, Western; Cell Differentiation; Cell Division; Fluorescent Antibody Technique; Hum

1992
Granulocyte colony-stimulating factor, not granulocyte-macrophage colony-stimulating factor, co-operates with retinoic acid on the induction of functional N-formyl-methionyl-phenylalanine receptors in HL-60 cells.
    Leukemia, 1991, Volume: 5, Issue:1

    Topics: Cell Differentiation; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulati

1991
Modulation of methotrexate cytotoxicity with natural interferon upon human leukemia cell line HL-60.
    Oncology, 1991, Volume: 48, Issue:6

    Topics: Biological Transport; Cell Division; Flow Cytometry; Humans; In Vitro Techniques; Interferon-alpha;

1991
Induction of differentiation in human HL-60 cells by 4-hydroxynonenal, a product of lipid peroxidation.
    Experimental cell research, 1991, Volume: 197, Issue:2

    Topics: Aldehydes; Alkaline Phosphatase; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA Replicatio

1991
Expression of memory to the terminal differentiation inducing activity of tiazofurin in HL-60 leukemia cells.
    Leukemia research, 1991, Volume: 15, Issue:5

    Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; DNA Rep

1991
Mechanism of interaction between interferon-gamma and antineoplastic agent on the differentiation of HL-60 promyelocytic cells.
    Experimental hematology, 1990, Volume: 18, Issue:3

    Topics: Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Drug Synergism; Fluorouracil; Huma

1990
Comparative studies on the action of 7-N-[2-[[2-(gamma-L-glutamylamino)ethyl]dithio]ethyl]mitomycin C and of mitomycin C on cultured HL-60 cells and isolated phage and plasmid DNA.
    Cancer chemotherapy and pharmacology, 1990, Volume: 26, Issue:2

    Topics: Antineoplastic Agents; Cell Division; Dithiothreitol; DNA; DNA Damage; DNA, Viral; Dose-Response Rel

1990
A protein complex expressed during terminal differentiation of monomyelocytic cells is an inhibitor of cell growth.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1990, Volume: 1, Issue:10

    Topics: Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Casein Kinases; Cell Differentiation; DNA, N

1990
Effects of 1-beta-D-arabinofuranosylcytosine on DNA replication intermediates monitored by pH-step alkaline elution.
    Cancer research, 1990, May-01, Volume: 50, Issue:9

    Topics: Arabinonucleotides; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Neoplasm; Humans; Hydr

1990
Granulocyte-colony stimulating factor and retinoic acid cooperatively induce granulocyte differentiation of acute promyelocytic leukemia cells in vitro.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:11

    Topics: Adult; Aged; Antigens, Surface; Cell Differentiation; Cell Survival; Colony-Stimulating Factors; Fem

1989
Synergistic effect of methotrexate and 1-beta-D-arabinofuranosylcytosine on the generation of DNA strand breaks in a human promyelocytic leukemia cell line.
    Leukemia research, 1989, Volume: 13, Issue:2

    Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA Damage; Drug Combinations; Drug Synergism; Human

1989
VP-16-induced nucleotide pool changes and poly(ADP-ribose) synthesis: the role of VP-16 in interphase death.
    Experimental cell research, 1989, Volume: 185, Issue:1

    Topics: Benzamides; Cell Line; Cell Survival; DNA Damage; Etoposide; Humans; Interphase; Leukemia, Promyeloc

1989
Demonstration of the cell cycle positions of taxol-induced "asters" and "bundles" by sequential measurements of tubulin immunofluorescence, DNA content, and autoradiographic labeling of taxol-sensitive and -resistant cells.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1989, Volume: 37, Issue:11

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Autoradiography; Cell Cycle; Cell Line; DNA; Drug Resi

1989
Sequential combination of methotrexate and 1-beta-D-arabinofuranosylcytosine shows synergistic effect on the generation of DNA strand breaks in a human promyelocytic leukemia cell line.
    Advances in experimental medicine and biology, 1989, Volume: 253B

    Topics: Arabinofuranosylcytosine Triphosphate; Cycloheximide; Cytarabine; DNA Damage; DNA, Neoplasm; Dose-Re

1989
Reversal of enzymic phenotype of thymidine metabolism in induced differentiation of HL-60 cells.
    Leukemia research, 1989, Volume: 13, Issue:12

    Topics: Cell Cycle; Cell Differentiation; Dihydrouracil Dehydrogenase (NAD+); DNA; Humans; Kinetics; Leukemi

1989
Mechanism of the induction of the differentiation of HL-60 leukemia cells by antifolates.
    Cancer communications, 1989, Volume: 1, Issue:3

    Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA Repl

1989