thymidine has been researched along with Leukemia, Promyelocytic, Acute in 40 studies
Leukemia, Promyelocytic, Acute: An acute myeloid leukemia in which abnormal PROMYELOCYTES predominate. It is frequently associated with DISSEMINATED INTRAVASCULAR COAGULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is uncertain if acute lymphoblastic leukemia (ALL) cells expressing myeloid makers can respond to granulocyte colony-stimulating factor (G-CSF) and granulocyte macrophage colony-stimulating factor (GM-CSF)." | 2.68 | Heterogeneous effects of G-CSF and GM-CSF on cell growth and ara-C cytotoxicity in childhood leukemias which express myeloid markers. ( Cao, DC; Higashigawa, M; Hori, H; Ido, M; Kawasaki, H; Komada, Y; Kuwabara, H; Ohkubo, T; Sakurai, M, 1996) |
| "The lignans and genistein were strongly suppressive against incorporations of [3H]thymidine, [3H]uridine, and [3H]leucine into HL-60 cells." | 1.29 | Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells. ( Gotoh, M; Hirano, T; Oka, K, 1994) |
| "Hydroxyl radicals were generated by a Fenton reaction, involving an ADP-Fe2+ (or ATP-Fe2+) complex and H2O2." | 1.29 | Induction of granulocytic maturation in HL-60 human leukemia cells by free radicals: a hypothesis of cell differentiation involving hydroxyl radicals. ( Bene, L; Nagy, K; Pásti, G; Zs-Nagy, I, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (17.50) | 18.7374 |
| 1990's | 29 (72.50) | 18.2507 |
| 2000's | 3 (7.50) | 29.6817 |
| 2010's | 1 (2.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rho, SB | 1 |
| Choi, K | 1 |
| Park, K | 1 |
| Lee, JH | 1 |
| Stervbo, U | 1 |
| Vang, O | 1 |
| Bonnesen, C | 1 |
| Yamaji, Y | 2 |
| Shiotani, T | 2 |
| Nakamura, H | 2 |
| Hata, Y | 1 |
| Hashimoto, Y | 2 |
| Nagai, M | 1 |
| Fujita, J | 2 |
| Takahara, J | 1 |
| Fraser, DJ | 1 |
| Brandt, TL | 1 |
| Kroll, DJ | 1 |
| Jones, EW | 1 |
| Manning, R | 1 |
| Lok, CN | 1 |
| Chan, KF | 1 |
| Loh, TT | 1 |
| Egan, MG | 1 |
| Sirlin, S | 1 |
| Rumberger, BG | 1 |
| Garrow, TA | 1 |
| Shane, B | 1 |
| Sirotnak, FM | 1 |
| Ryves, WJ | 1 |
| Dimitrijevic, S | 1 |
| Gordge, PC | 1 |
| Evans, FJ | 1 |
| Tanaka, Y | 1 |
| Yoshihara, K | 1 |
| Tsuyuki, M | 1 |
| Kamiya, T | 1 |
| Defacque, H | 1 |
| Commes, T | 1 |
| Sevilla, C | 1 |
| Rochette-Egly, C | 1 |
| Marti, J | 1 |
| Hirano, T | 1 |
| Gotoh, M | 1 |
| Oka, K | 1 |
| Pérez-Sala, D | 1 |
| Mollinedo, F | 1 |
| Nagy, K | 1 |
| Pásti, G | 1 |
| Bene, L | 1 |
| Zs-Nagy, I | 1 |
| Nishiguchi, Y | 1 |
| Hibasami, H | 1 |
| Komada, Y | 2 |
| Sakurai, M | 2 |
| Nakashima, K | 1 |
| Norman, AW | 1 |
| Bouillon, R | 1 |
| Farach-Carson, MC | 1 |
| Bishop, JE | 1 |
| Zhou, LX | 1 |
| Nemere, I | 1 |
| Zhao, J | 1 |
| Muralidharan, KR | 1 |
| Okamura, WH | 1 |
| Berczi, A | 1 |
| Barabas, K | 1 |
| Sizensky, JA | 1 |
| Faulk, WP | 1 |
| Miyazaki, Y | 1 |
| Katamine, S | 1 |
| Kohno, T | 1 |
| Moriuchi, R | 1 |
| Miyamoto, T | 1 |
| Tomonaga, M | 1 |
| Higashigawa, M | 1 |
| Kuwabara, H | 1 |
| Cao, DC | 1 |
| Hori, H | 1 |
| Ohkubo, T | 1 |
| Kawasaki, H | 1 |
| Ido, M | 1 |
| Katayama, N | 1 |
| Kita, K | 1 |
| Kawakami, K | 1 |
| Mitani, H | 1 |
| Sugawara, T | 1 |
| Mizuno, S | 1 |
| Yonezawa, A | 1 |
| Nishii, K | 1 |
| Miwa, H | 1 |
| Wada, H | 1 |
| Minami, N | 1 |
| Shiku, H | 1 |
| Matsuhisa, T | 1 |
| Pratsinis, H | 1 |
| Haroutounian, SA | 1 |
| Grant, S | 1 |
| Jarvis, WD | 1 |
| Swerdlow, PS | 1 |
| Turner, AJ | 1 |
| Traylor, RS | 1 |
| Wallace, HJ | 1 |
| Lin, PS | 1 |
| Pettit, GR | 1 |
| Gewirtz, DA | 1 |
| Solary, E | 1 |
| Bertrand, R | 1 |
| Jenkins, J | 1 |
| Pommier, Y | 1 |
| Vassiliadis, S | 1 |
| Kyrpides, N | 1 |
| Papamatheakis, J | 1 |
| Paulin-Levasseur, M | 1 |
| Julien, M | 1 |
| Sakashita, A | 2 |
| Nakamaki, T | 2 |
| Tsuruoka, N | 2 |
| Honma, Y | 2 |
| Hozumi, M | 2 |
| Sur, P | 1 |
| Matsuo, Y | 1 |
| Otani, T | 1 |
| Minowada, J | 1 |
| Barrera, G | 1 |
| Di Mauro, C | 1 |
| Muraca, R | 1 |
| Ferrero, D | 1 |
| Cavalli, G | 1 |
| Fazio, VM | 1 |
| Paradisi, L | 1 |
| Dianzani, MU | 1 |
| Sokoloski, JA | 2 |
| Sartorelli, AC | 2 |
| Kafka, M | 1 |
| Dvilansky, A | 1 |
| Nathan, I | 1 |
| Ishioka, C | 1 |
| Kanamaru, R | 1 |
| Konishi, Y | 1 |
| Ishikawa, A | 1 |
| Shibata, H | 1 |
| Wakui, A | 1 |
| Murao, S | 1 |
| Collart, F | 1 |
| Huberman, E | 1 |
| Ross, DD | 1 |
| Chen, SR | 1 |
| Cuddy, DP | 1 |
| Sano, M | 1 |
| Hino, K | 1 |
| Suzuki, K | 1 |
| Tomoyasu, S | 1 |
| Tanizawa, A | 3 |
| Kubota, M | 3 |
| Takimoto, T | 3 |
| Kito, T | 2 |
| Akiyama, Y | 3 |
| Kiriyama, Y | 2 |
| Mikawa, H | 3 |
| Hashimoto, H | 1 |
| Shimizu, T | 1 |
| Kitoh, T | 1 |
| Roberts, JR | 1 |
| Rowinsky, EK | 1 |
| Donehower, RC | 1 |
| Robertson, J | 1 |
| Allison, DC | 1 |
| Futami, H | 1 |
| Yamauchi, N | 1 |
| Bungo, M | 1 |
| Tanaka, T | 1 |
| Irino, S | 1 |
| Beardsley, GP | 1 |
1 review available for thymidine and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Reciprocal alterations of enzymic phenotype of purine and pyrimidine metabolism in induced differentiation of leukemia cells.
Topics: Cell Cycle; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; GMP Reductase; Humans; IMP Dehydrog | 1994 |
1 trial available for thymidine and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Heterogeneous effects of G-CSF and GM-CSF on cell growth and ara-C cytotoxicity in childhood leukemias which express myeloid markers.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Arabinofuranosylcytosine Triphosphate; C | 1996 |
38 other studies available for thymidine and Leukemia, Promyelocytic, Acute
| Article | Year |
|---|---|
Inhibition of angiogenesis by the BTB domain of promyelocytic leukemia zinc finger protein.
Topics: Animals; Cell Cycle; Cell Movement; Chickens; Chorioallantoic Membrane; Cloning, Molecular; Cyclin A | 2010 |
Time- and concentration-dependent effects of resveratrol in HL-60 and HepG2 cells.
Topics: Annexin A5; Anticarcinogenic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Nucleus | 2006 |
Topoisomerase II alpha promoter trans-activation early in monocytic differentiation of HL-60 human leukemia cells.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; DNA Topoisomerases, Type II; Genes, Re | 1995 |
Cytotoxic effects of membrane-active agents in human leukaemia cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Culture Media, Serum-Free; Dibucaine | 1995 |
Effects of protein kinase modulators on transferrin receptor expression in human leukaemic HL-60 cells.
Topics: Alkaloids; Bucladesine; Cell Division; Cell Line; Cyclic AMP-Dependent Protein Kinases; DNA, Neoplas | 1995 |
Rapid decline in folylpolyglutamate synthetase activity and gene expression during maturation of HL-60 cells. Nature of the effect, impact on folate compound polyglutamate pools, and evidence for programmed down-regulation during maturation.
Topics: Blotting, Northern; Cell Division; Cell Line; Dimethyl Sulfoxide; gamma-Glutamyl Hydrolase; Gene Exp | 1995 |
HL-60 cell differentiation induced by phorbol- and 12-deoxyphorbol-esters.
Topics: Cell Differentiation; Humans; Leukemia, Promyelocytic, Acute; Phorbol Esters; Protein Kinase C; Tetr | 1994 |
Apoptosis induced by adenosine in human leukemia HL-60 cells.
Topics: Adenine Nucleotides; Adenosine; Apoptosis; Cell Line; Coformycin; Deoxyadenosines; Deoxyguanosine; D | 1994 |
Synergistic differentiation of U937 cells by all-trans retinoic acid and 1 alpha, 25-dihydroxyvitamin D3 is associated with the expression of retinoid X receptor alpha.
Topics: Animals; Blotting, Western; Calcitriol; Cell Differentiation; Cell Division; Cell Line; Cell Nucleus | 1994 |
Natural flavonoids and lignans are potent cytostatic agents against human leukemic HL-60 cells.
Topics: Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Flavonoids; Humans; Leucine; | 1994 |
Inhibition of isoprenoid biosynthesis induces apoptosis in human promyelocytic HL-60 cells.
Topics: Apoptosis; Cell Division; Cell Line; Cell Survival; DNA Damage; DNA, Neoplasm; Humans; Kinetics; Leu | 1994 |
Induction of granulocytic maturation in HL-60 human leukemia cells by free radicals: a hypothesis of cell differentiation involving hydroxyl radicals.
Topics: Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA Replication; Flow Cytometry; | 1993 |
Human promyelocytic cell line HL60 has the specific binding sites for prolactin and its ornithine decarboxylase, DNA synthesis and cellular proliferation are induced by prolactin.
Topics: Binding Sites; Carbon Radioisotopes; Cell Division; DNA Replication; DNA, Neoplasm; Dose-Response Re | 1993 |
Demonstration that 1 beta,25-dihydroxyvitamin D3 is an antagonist of the nongenomic but not genomic biological responses and biological profile of the three A-ring diastereomers of 1 alpha,25-dihydroxyvitamin D3.
Topics: Animals; Bone and Bones; Calcitriol; Calcium; Cell Division; Cell Nucleus; Cells, Cultured; Chickens | 1993 |
Adriamycin conjugates of human transferrin bind transferrin receptors and kill K562 and HL60 cells.
Topics: Cell Survival; DNA Replication; Doxorubicin; Humans; Iodine Radioisotopes; Kinetics; Leukemia, Myelo | 1993 |
fgr proto-oncogene is expressed during terminal granulocytic differentiation of human promyelocytic HL60 cells.
Topics: Cell Transformation, Neoplastic; Dimethyl Sulfoxide; DNA, Neoplasm; Gene Expression Regulation, Neop | 1993 |
Granulocyte colony-stimulating factor and its receptor in acute promyelocytic leukemia.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Female; Fluorescent Antibody Technique; Granu | 1998 |
Terminal differentiation of human promyelocytic leukaemia cells, HL-60, during the G1 period.
Topics: Calcitriol; Cell Differentiation; DNA, Neoplasm; G1 Phase; HL-60 Cells; Humans; Hydroxyurea; Leukemi | 2001 |
Synthesis and antioxidant activity of 3-substituted guaiazulene derivatives.
Topics: alpha-Tocopherol; Antineoplastic Agents; Antioxidants; Azulenes; Catalysis; Drug Screening Assays, A | 2002 |
Potentiation of the activity of 1-beta-D-arabinofuranosylcytosine by the protein kinase C activator bryostatin 1 in HL-60 cells: association with enhanced fragmentation of mature DNA.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apopt | 1992 |
Radiolabeling of DNA can induce its fragmentation in HL-60 human promyelocytic leukemic cells.
Topics: Apoptosis; Cell Division; DNA Damage; DNA, Neoplasm; Humans; Leukemia, Promyelocytic, Acute; Thymidi | 1992 |
The role of IL-4 in human myeloid leukemia: stimulation of RNA synthesis and transduction of differentiation signals through an IL-4 receptor leads to functional and HLA positive HL-60 cells.
Topics: Cell Differentiation; Cell Division; Cellular Senescence; DNA, Neoplasm; Histocompatibility Antigens | 1992 |
Expression of intermediate filament proteins in TPA-induced MPC-11 and HL-60 cells.
Topics: Animals; Blotting, Western; Cell Differentiation; Cell Division; Fluorescent Antibody Technique; Hum | 1992 |
Granulocyte colony-stimulating factor, not granulocyte-macrophage colony-stimulating factor, co-operates with retinoic acid on the induction of functional N-formyl-methionyl-phenylalanine receptors in HL-60 cells.
Topics: Cell Differentiation; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulati | 1991 |
Modulation of methotrexate cytotoxicity with natural interferon upon human leukemia cell line HL-60.
Topics: Biological Transport; Cell Division; Flow Cytometry; Humans; In Vitro Techniques; Interferon-alpha; | 1991 |
Induction of differentiation in human HL-60 cells by 4-hydroxynonenal, a product of lipid peroxidation.
Topics: Aldehydes; Alkaline Phosphatase; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA Replicatio | 1991 |
Expression of memory to the terminal differentiation inducing activity of tiazofurin in HL-60 leukemia cells.
Topics: Antimetabolites, Antineoplastic; Cell Cycle; Cell Differentiation; Cell Line; Cycloheximide; DNA Rep | 1991 |
Mechanism of interaction between interferon-gamma and antineoplastic agent on the differentiation of HL-60 promyelocytic cells.
Topics: Cell Differentiation; Cell Division; Cycloheximide; Dactinomycin; Drug Synergism; Fluorouracil; Huma | 1990 |
Comparative studies on the action of 7-N-[2-[[2-(gamma-L-glutamylamino)ethyl]dithio]ethyl]mitomycin C and of mitomycin C on cultured HL-60 cells and isolated phage and plasmid DNA.
Topics: Antineoplastic Agents; Cell Division; Dithiothreitol; DNA; DNA Damage; DNA, Viral; Dose-Response Rel | 1990 |
A protein complex expressed during terminal differentiation of monomyelocytic cells is an inhibitor of cell growth.
Topics: Calcium-Binding Proteins; Calgranulin A; Calgranulin B; Casein Kinases; Cell Differentiation; DNA, N | 1990 |
Effects of 1-beta-D-arabinofuranosylcytosine on DNA replication intermediates monitored by pH-step alkaline elution.
Topics: Arabinonucleotides; Cytarabine; Cytidine Monophosphate; DNA Replication; DNA, Neoplasm; Humans; Hydr | 1990 |
Granulocyte-colony stimulating factor and retinoic acid cooperatively induce granulocyte differentiation of acute promyelocytic leukemia cells in vitro.
Topics: Adult; Aged; Antigens, Surface; Cell Differentiation; Cell Survival; Colony-Stimulating Factors; Fem | 1989 |
Synergistic effect of methotrexate and 1-beta-D-arabinofuranosylcytosine on the generation of DNA strand breaks in a human promyelocytic leukemia cell line.
Topics: Aphidicolin; Cell Line; Cytarabine; Diterpenes; DNA Damage; Drug Combinations; Drug Synergism; Human | 1989 |
VP-16-induced nucleotide pool changes and poly(ADP-ribose) synthesis: the role of VP-16 in interphase death.
Topics: Benzamides; Cell Line; Cell Survival; DNA Damage; Etoposide; Humans; Interphase; Leukemia, Promyeloc | 1989 |
Demonstration of the cell cycle positions of taxol-induced "asters" and "bundles" by sequential measurements of tubulin immunofluorescence, DNA content, and autoradiographic labeling of taxol-sensitive and -resistant cells.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Autoradiography; Cell Cycle; Cell Line; DNA; Drug Resi | 1989 |
Sequential combination of methotrexate and 1-beta-D-arabinofuranosylcytosine shows synergistic effect on the generation of DNA strand breaks in a human promyelocytic leukemia cell line.
Topics: Arabinofuranosylcytosine Triphosphate; Cycloheximide; Cytarabine; DNA Damage; DNA, Neoplasm; Dose-Re | 1989 |
Reversal of enzymic phenotype of thymidine metabolism in induced differentiation of HL-60 cells.
Topics: Cell Cycle; Cell Differentiation; Dihydrouracil Dehydrogenase (NAD+); DNA; Humans; Kinetics; Leukemi | 1989 |
Mechanism of the induction of the differentiation of HL-60 leukemia cells by antifolates.
Topics: Antibodies, Monoclonal; Cell Differentiation; Cell Division; Cell Line; Dimethyl Sulfoxide; DNA Repl | 1989 |