thymidine has been researched along with B-Cell Chronic Lymphocytic Leukemia in 23 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The cellular response of peripheral blood mononuclear cells (PBMC) from patients with B-cell chronic lymphocytic leukemia to increasing doses of acyclovir was examined by their capacity to incorporate 3H-TdR, and their response to phytohemagglutinin, concanavalin A and pokeweed mitogen." | 5.08 | The effect of acyclovir on the proliferative capacity of mononuclear cells from patients with chronic lymphocytic leukemia. ( Bessler, H; Djaldetti, R; Salman, H; Straussberg, R, 1996) |
| "T lymphocytes from patients with B cell chronic lymphocytic leukemia (B-CLL) exhibit defective proliferative response to plant lectins." | 1.29 | Diminished DNA synthesis in T cells from B chronic lymphocytic leukemia after phytohemagglutinin, anti-CD3, and phorbol myristate acetate mitogenic signals. ( Alvarez-Mon, M; Garcia-Suarez, J; Hernandez, M; Lapeña, P; Prieto, A; Reyes, E, 1993) |
| "Thymidine uptake was not associated with Rai or Binet stage, but following mitogenic stimulation it was significantly greater in CLL-cell clones with an extra chromosome 12 or multiple chromosomal aberrations as compared to cell clones with normal karyotypes." | 1.27 | Clinical implications of CLL cell proliferation in vitro. ( Gahrton, G; Juliusson, G, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (26.09) | 18.7374 |
| 1990's | 10 (43.48) | 18.2507 |
| 2000's | 5 (21.74) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sainz-Perez, A | 1 |
| Gary-Gouy, H | 1 |
| Gaudin, F | 1 |
| Maarof, G | 1 |
| Marfaing-Koka, A | 1 |
| de Revel, T | 1 |
| Dalloul, A | 1 |
| Coppola, N | 1 |
| Masiello, A | 1 |
| Tonziello, G | 1 |
| Macera, M | 1 |
| Iodice, V | 1 |
| Caprio, N | 1 |
| Pasquale, G | 1 |
| Veselá, R | 1 |
| Doležalová, L | 1 |
| Pytlík, R | 1 |
| Rychtrmocová, H | 1 |
| Marečková, H | 1 |
| Trněný, M | 1 |
| Breslin, EM | 1 |
| White, PC | 1 |
| Shore, AM | 1 |
| Clement, M | 1 |
| Brennan, P | 1 |
| Castro, JE | 1 |
| Prada, CE | 1 |
| Aguillon, RA | 1 |
| Kitada, S | 1 |
| Fukuda, T | 1 |
| Motta, M | 1 |
| Wu, C | 1 |
| Dicker, F | 1 |
| Sun, G | 1 |
| Wang, JY | 1 |
| Carson, DA | 1 |
| Reed, JC | 1 |
| Kipps, TJ | 2 |
| Crawford, DH | 1 |
| Catovsky, D | 1 |
| Panayiotidis, P | 1 |
| Ganeshaguru, K | 1 |
| Jabbar, SA | 1 |
| Hoffbrand, AV | 1 |
| Lotz, M | 1 |
| Ranheim, E | 1 |
| Kalvelyté, A | 1 |
| Pabrézaité, L | 1 |
| Prieto, A | 1 |
| Garcia-Suarez, J | 1 |
| Reyes, E | 1 |
| Lapeña, P | 1 |
| Hernandez, M | 1 |
| Alvarez-Mon, M | 1 |
| Jewell, AP | 1 |
| Lydyard, PM | 1 |
| Worman, CP | 1 |
| Giles, FJ | 1 |
| Goldstone, AH | 1 |
| Bessler, H | 1 |
| Straussberg, R | 1 |
| Djaldetti, R | 1 |
| Salman, H | 1 |
| DeCoteau, JF | 1 |
| Knaus, PI | 1 |
| Yankelev, H | 1 |
| Reis, MD | 1 |
| Lowsky, R | 1 |
| Lodish, HF | 1 |
| Kadin, ME | 1 |
| Van Den Neste, E | 1 |
| Cardoen, S | 1 |
| Husson, B | 1 |
| Rosier, JF | 1 |
| Delacauw, A | 1 |
| Ferrant, A | 1 |
| Van den Berghe, G | 1 |
| Bontemps, F | 1 |
| Decker, T | 1 |
| Schneller, F | 1 |
| Hipp, S | 1 |
| Miething, C | 1 |
| Jahn, T | 1 |
| Duyster, J | 1 |
| Peschel, C | 1 |
| del Giglio, A | 1 |
| O'Brien, S | 1 |
| Ford, R | 1 |
| Saya, H | 1 |
| Manning, J | 1 |
| Keating, M | 1 |
| Johnston, D | 1 |
| Khetan, R | 1 |
| el-Naggar, A | 1 |
| Deisseroth, A | 1 |
| Bentley, DP | 1 |
| Blackmore, JA | 1 |
| Juliusson, G | 1 |
| Gahrton, G | 1 |
| Ostlund, L | 1 |
| Biberfeld, P | 1 |
| Robèrt, KH | 1 |
| Christensson, B | 1 |
| Einhorn, S | 1 |
| Rao, S | 1 |
| Coleman, PS | 1 |
| Digel, W | 1 |
| Stefanic, M | 1 |
| Schöniger, W | 1 |
| Buck, C | 1 |
| Raghavachar, A | 1 |
| Frickhofen, N | 1 |
| Heimpel, H | 1 |
| Porzsolt, F | 1 |
| Measel, JW | 1 |
| Cammarata, P | 1 |
| Ferguson, KA | 1 |
| Distefano, A | 1 |
| Sokal, JE | 1 |
| Pauly, JL | 1 |
1 trial available for thymidine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
The effect of acyclovir on the proliferative capacity of mononuclear cells from patients with chronic lymphocytic leukemia.
Topics: Acyclovir; Antimetabolites; Concanavalin A; Dose-Response Relationship, Drug; Humans; Leukemia, Lymp | 1996 |
22 other studies available for thymidine and B-Cell Chronic Lymphocytic Leukemia
| Article | Year |
|---|---|
IL-24 induces apoptosis of chronic lymphocytic leukemia B cells engaged into the cell cycle through dephosphorylation of STAT3 and stabilization of p53 expression.
Topics: Adult; Apoptosis; B-Lymphocytes; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Humans; Interleuk | 2008 |
[Icteric hepatitis in a patient with non-Hodgkin's lymphoma treated by rituximab-based chemotherapy].
Topics: Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Antiviral Ag | 2010 |
The evaluation of survival and proliferation of lymphocytes in autologous mixed leukocyte reaction with dendritic cells. The comparison of incorporation of (3)H-thymidine and differential gating method.
Topics: Aged; Aged, 80 and over; Antigens, CD; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell | 2011 |
LY294002 and rapamycin co-operate to inhibit T-cell proliferation.
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Drug Interactions; Enzyme Inhibitors | 2005 |
Thymidine-phosphorothioate oligonucleotides induce activation and apoptosis of CLL cells independently of CpG motifs or BCL-2 gene interference.
Topics: Amino Acid Chloromethyl Ketones; Apoptosis; B-Lymphocytes; Benzamides; BH3 Interacting Domain Death | 2006 |
In vitro activation of leukaemic B cells by interleukin-4 and antibodies to CD40.
Topics: Antibodies; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; B-Lymphocytes; CD40 Antigens; Cel | 1993 |
Alpha-interferon (alpha-IFN) protects B-chronic lymphocytic leukaemia cells from apoptotic cell death in vitro.
Topics: Aged; Aged, 80 and over; Apoptosis; Blotting, Western; DNA, Neoplasm; Female; Humans; Hydrocortisone | 1994 |
Transforming growth factor beta as endogenous growth inhibitor of chronic lymphocytic leukemia B cells.
Topics: Aged; Animals; B-Lymphocytes; Cells, Cultured; Humans; Immunoglobulin G; Leukemia, Lymphocytic, Chro | 1994 |
Phenomena of spontaneous proliferation, differentiation, and apoptosis in primary culture of leukemic lymphocytes.
Topics: Animals; Apoptosis; Cattle; Cell Differentiation; Cell Division; DNA, Neoplasm; Kinetics; Leukemia V | 1994 |
Diminished DNA synthesis in T cells from B chronic lymphocytic leukemia after phytohemagglutinin, anti-CD3, and phorbol myristate acetate mitogenic signals.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; CD3 Complex; Cell Division; Cells, Cultured; DNA; F | 1993 |
Growth factors can protect B-chronic lymphocytic leukaemia cells against programmed cell death without stimulating proliferation.
Topics: Apoptosis; Cell Division; Cytokines; DNA, Neoplasm; Humans; Interferon Type I; Leukemia, Lymphocytic | 1995 |
Loss of functional cell surface transforming growth factor beta (TGF-beta) type 1 receptor correlates with insensitivity to TGF-beta in chronic lymphocytic leukemia.
Topics: Activin Receptors, Type I; Adult; Antigens, CD; Cell Division; Cell Membrane; DNA, Neoplasm; Humans; | 1997 |
2-Chloro-2'-deoxyadenosine inhibits DNA repair synthesis and potentiates UVC cytotoxicity in chronic lymphocytic leukemia B lymphocytes.
Topics: Alkylating Agents; Alkylation; Antimetabolites, Antineoplastic; Apoptosis; B-Lymphocytes; Caspase 3; | 2002 |
Cell cycle progression of chronic lymphocytic leukemia cells is controlled by cyclin D2, cyclin D3, cyclin-dependent kinase (cdk) 4 and the cdk inhibitor p27.
Topics: Apoptosis; B-Lymphocytes; Cell Cycle; Cell Cycle Proteins; Cyclin D1; Cyclin D2; Cyclin D3; Cyclin-D | 2002 |
Prognostic value of proliferating cell nuclear antigen expression in chronic lymphoid leukemia.
Topics: Actins; Antigens, CD; Antigens, Neoplasm; Biomarkers, Tumor; Blotting, Western; Bone Marrow; DNA Rep | 1992 |
The inhibition of DNA synthesis in chronic lymphocytic leukaemia cells by chlorambucil in vitro.
Topics: Chlorambucil; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fem | 1992 |
Clinical implications of CLL cell proliferation in vitro.
Topics: B-Lymphocytes; Dextran Sulfate; Dextrans; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lipopolysa | 1988 |
Induction of proliferation and blast transformation by interferon in human malignant and non-malignant lymph node B cells.
Topics: Adult; Aged; Antigens, Differentiation; B-Lymphocytes; Cell Separation; Cell Transformation, Neoplas | 1989 |
Control of DNA replication and cell growth by inhibiting the export of mitochondrially derived citrate.
Topics: Animals; Benzene Derivatives; Biological Transport; Calcimycin; Cell Line; Cell Nucleus; Citrates; D | 1989 |
Tumor necrosis factor induces proliferation of neoplastic B cells from chronic lymphocytic leukemia.
Topics: Adult; Aged; B-Lymphocytes; Cell Division; Female; Growth Substances; Humans; Leukemia, Lymphocytic, | 1989 |
Enhancement of mixed lymphocyte culture reactions between donor and recipient in B cell chronic leukemia using antibody-coated beads.
Topics: Antibodies; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphocyte Culture Test, | 1988 |
In vitro thymidine uptake by circulating leukocytes.
Topics: Adult; Biological Transport; Cells, Cultured; Hematologic Diseases; Humans; Leukemia; Leukemia, Lymp | 1974 |