thymidine has been researched along with Leprosy in 21 studies
Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As thalidomide is an effective treatment for ENL, this study assessed the effect of this drug on these phenomena." | 5.32 | Thalidomide does not modify the ability of cells in leprosy patients to incorporate [3H]-thymidine when incubated with M. leprae antigens. ( Sandoval, F; Shannon, EJ; Tadesse, A; Taye, E, 2003) |
| "We have examined the capacity of monocytes from patients with leprosy to undergo activation and the capacity of mononuclear cells from these patients to incorporate [3H]thymidine and produce monocyte-activating cytokines." | 3.67 | Defective production of monocyte-activating cytokines in lepromatous leprosy. ( Cohn, ZA; Horwitz, MA; Levis, WR, 1984) |
| "As thalidomide is an effective treatment for ENL, this study assessed the effect of this drug on these phenomena." | 1.32 | Thalidomide does not modify the ability of cells in leprosy patients to incorporate [3H]-thymidine when incubated with M. leprae antigens. ( Sandoval, F; Shannon, EJ; Tadesse, A; Taye, E, 2003) |
| "The antibacterial effect of brodimoprim alone and in combination with dapsone has been studied in vitro in cell-free systems and in whole mycobacterial cells as well as in vivo in mice and humans." | 1.28 | In vitro and in vivo experiments with the new inhibitor of mycobacterium leprae brodimoprim alone and in combination with dapsone. ( Dhople, AM; Jagannathan, R; Mahadevan, PR; Rosenfeld, M; Seydel, JK; Wempe, EG, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (80.95) | 18.7374 |
| 1990's | 3 (14.29) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tadesse, A | 1 |
| Taye, E | 1 |
| Sandoval, F | 1 |
| Shannon, EJ | 1 |
| Mittal, A | 1 |
| Sathish, M | 2 |
| Seshadri, PS | 1 |
| Nath, I | 4 |
| Horwitz, MA | 1 |
| Levis, WR | 1 |
| Cohn, ZA | 1 |
| Jayaraman, T | 1 |
| Bhutani, LK | 2 |
| Sharma, AK | 1 |
| Prasad, HK | 2 |
| Singh, R | 1 |
| Weir, RE | 1 |
| Morgan, AR | 1 |
| Britton, WJ | 1 |
| Butlin, CR | 1 |
| Dockrell, HM | 1 |
| Dhople, AM | 2 |
| Ambrose, EJ | 1 |
| Khanolkar, SR | 1 |
| Antia, NH | 1 |
| Chulawalla, RG | 1 |
| Koticha, KK | 1 |
| Evans, MJ | 1 |
| Levy, L | 1 |
| Bjune, G | 1 |
| Seydel, JK | 1 |
| Wempe, EG | 1 |
| Rosenfeld, M | 1 |
| Jagannathan, R | 1 |
| Mahadevan, PR | 1 |
| Barnass, S | 1 |
| Mace, J | 1 |
| Steele, J | 1 |
| Torres, P | 1 |
| Gervasoni, B | 1 |
| Ravioli, R | 1 |
| Terencio, J | 1 |
| Rook, GA | 1 |
| Waters, MF | 1 |
| Harshan, KV | 1 |
| Chopra, NK | 1 |
| Mishra, RS | 1 |
| Gogiya, P | 1 |
| Talwar, GP | 3 |
| Krishnan, AD | 2 |
| Gupta, PD | 1 |
| Drutz, DJ | 1 |
| Cline, MJ | 1 |
| Bullock, WE | 2 |
| Fields, JP | 1 |
| Brandriss, MW | 1 |
| Mehra, VL | 2 |
| Blum, EA | 1 |
| Pearson, JM | 1 |
| Myrvang, B | 2 |
| Godal, T | 2 |
| Ridley, DS | 1 |
| Fröland, SS | 1 |
| Song, YK | 1 |
| Balakrishnan, K | 1 |
| Myklestad, B | 1 |
| Samuel, DR | 1 |
| Fasal, P | 1 |
21 other studies available for thymidine and Leprosy
| Article | Year |
|---|---|
Thalidomide does not modify the ability of cells in leprosy patients to incorporate [3H]-thymidine when incubated with M. leprae antigens.
Topics: Adolescent; Adult; Aged; Antigens, Bacterial; Cell Division; Female; Humans; Leprostatic Agents; Lep | 2003 |
Rapid, radiolabeled-microculture method that uses macrophages for in vitro evaluation of Mycobacterium leprae viability and drug susceptibility.
Topics: Adult; Animals; Cells, Cultured; Dapsone; Female; Humans; In Vitro Techniques; Leprosy; Macrophages; | 1983 |
Defective production of monocyte-activating cytokines in lepromatous leprosy.
Topics: Adult; Biological Products; Blood Bactericidal Activity; Cytokines; Cytotoxicity, Immunologic; Femal | 1984 |
Evidence for the presence of M. leprae reactive T lymphocytes in patients with lepromatous leprosy.
Topics: Antigens, Bacterial; Cell Adhesion; Cells, Cultured; Histocompatibility Antigens Class II; Histocomp | 1984 |
Radiolabelled M. leprae resident in human macrophage cultures as an in vitro indicator of effective immunity in human leprosy.
Topics: Cells, Cultured; Humans; Leprosy; Lymphokines; Macrophages; Mycobacterium leprae; T-Lymphocytes; Thy | 1982 |
Development of a whole blood assay to measure T cell responses to leprosy: a new tool for immuno-epidemiological field studies of leprosy immunity.
Topics: Antigens, Bacterial; Enzyme-Linked Immunosorbent Assay; Humans; Immunity, Cellular; Interferon-gamma | 1994 |
Factors influencing the in vitro growth of Mycobacterium leprae: effect of inoculum.
Topics: Adenosine Triphosphate; Animals; Armadillos; Cobalt Radioisotopes; Culture Media; Humans; Leprosy; L | 1998 |
Rapid test for drug resistance in leprosy.
Topics: Dapsone; Dihydroxyphenylalanine; Drug Resistance, Microbial; Humans; In Vitro Techniques; Isotope La | 1977 |
Failure of Mycobacterium leprae to incorporate tritiated thymidine administered in vivo.
Topics: Animals; Leprosy; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mycobacterium leprae; Thymidine | 1977 |
In vitro lymphocyte stimulation in leprosy; simultaneous stimulation with Mycobacterium leprae antigens and phytohaemagglutinin.
Topics: Antigens, Bacterial; Antigens, Surface; Dose-Response Relationship, Immunologic; Humans; Leprosy; Ly | 1979 |
In vitro and in vivo experiments with the new inhibitor of mycobacterium leprae brodimoprim alone and in combination with dapsone.
Topics: Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Dapsone; Drug Interactions; L | 1990 |
Prevalence and specificity of the enhancing effect of three types of interleukin 2 on T cell responsiveness in 97 lepromatous leprosy patients of mixed ethnic origin.
Topics: Antigens, Bacterial; Dose-Response Relationship, Immunologic; Epitopes; Humans; Interleukin-2; Lepro | 1986 |
Comparison of radiometric macrophage assay and fluorescein diacetate/ethidium bromide staining for evaluation of M. leprae viability.
Topics: Bacteriological Techniques; Cells, Cultured; DNA, Bacterial; Ethidium; Fluoresceins; Humans; Leprosy | 1987 |
Quantitative evaluation of the progress of intracellular infection in vitro: incorporation of 3H-thymidine into deoxyribonucleic acid by Mycobacterium leprae in cultivated blood monocytes.
Topics: Autoradiography; Cells, Cultured; DNA, Bacterial; Infections; Leprosy; Macrophages; Microscopy, Elec | 1974 |
Incorporation of tritiated thymidine by leprosy bacilli in cultures of human lepromatous macrophages.
Topics: Autoradiography; Cells, Cultured; DNA, Bacterial; Humans; In Vitro Techniques; Leprosy; Macrophages; | 1972 |
An evaluation of transfer factor as immunotherapy for patients with lepromatous leprosy.
Topics: Adult; Antigens, Bacterial; Biopsy; Humans; Hypersensitivity, Delayed; Immunity, Maternally-Acquired | 1972 |
Evaluation of cell mediated immune responses in untreated cases of leprosy.
Topics: Animals; Antigens, Bacterial; Biopsy; Cell Aggregation; Cell Movement; Chromium Isotopes; Humans; Hy | 1972 |
Immune responsiveness to Mycobacterium leprae and other mycobacterial antigens throughout the clinical and histopathological spectrum of leprosy.
Topics: Antigens, Bacterial; Cell Migration Inhibition; Humans; Leprosy; Leukocytes; Lymphocyte Activation; | 1973 |
Influence of chemotherapy and serum factors on the mitogenic response of peripheral leucocytes of leprosy patients to phytohaemagglutinin.
Topics: Adolescent; Adult; Dapsone; DNA; Female; Humans; Lectins; Leprosy; Leukocytes; Lymphocyte Activation | 1972 |
Characterization of the cellular immune defect in lepromatous leprosy: a specific lack of circulating Mycobacterium leprae-reactive lymphocytes.
Topics: Adolescent; Adult; Child; Female; Humans; Immune Tolerance; Immunity, Cellular; Leprosy; Leukocytes; | 1971 |
Studies of immune mechanisms in leprosy. 3. The role of cellular and humoral factors in impairment of the in vitro immune response.
Topics: Adult; Antibody Formation; Antigens; Asian People; Black People; Culture Techniques; DNA; Female; Hu | 1971 |