thymidine has been researched along with Kidney Failure, Chronic in 28 studies
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Telbivudine was well tolerated by all subjects." | 2.73 | Pharmacokinetics of telbivudine in subjects with various degrees of renal impairment. ( Brown, NA; Chao, GC; Dubuc-Patrick, G; Marbury, TC; Smith, WB; Swan, S; Zhou, XJ, 2007) |
| "Calcitriol has shown a benefit in various small uncontrolled studies of ex vivo immune function." | 2.70 | A placebo-controlled trial to evaluate immunomodulatory effects of paricalcitol. ( Ambrosius, WT; Batiuk, TD; Gassensmith, CM; Harezlak, J; Moe, SM; Murphy, CL; Russell, RR; Zekonis, M, 2001) |
| "[3H]-thymidine uptake was tested in human visceral glomerular epithelial cells (vGEC) and mitogen-activated protein kinase (MAPK42/44) activation in vGEC and kidney cortex." | 1.31 | ATP release in human kidney cortex and its mitogenic effects in visceral glomerular epithelial cells. ( Amann, K; Apel, TW; Oberhauser, V; Ritz, E; Rump, LC; von Kügelgen, I; Vonend, O, 2002) |
| "Left ventricular hypertrophy is very prevalent among patients with renal insufficiency." | 1.29 | Serum from patients with chronic renal insufficiency alters growth characteristics and ANP mRNA expression of adult rat cardiac myocytes. ( Allard, MF; Bondy, GP; Levin, A; McManus, BM; Thompson, CR; Yu, JZ, 1996) |
| "End stage renal disease (ESRD) kidneys display abnormal growth characterized by a continuum of cystic disease, adenoma and carcinoma." | 1.28 | End stage renal disease serum contains a specific renal cell growth factor. ( Klotz, LH; Kulkarni, C; Mills, G, 1991) |
| "Thymidine incorporation was greatest at 0." | 1.25 | Effect of calcium and magnesium on deoxyribonucleic acid synthesis in rat parathyroid glands in vitro. ( Lee, MJ; Roth, SI, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (53.57) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 6 (21.43) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sfar, I | 1 |
| Gorgi, Y | 1 |
| Aouadi, H | 1 |
| Maklouf, M | 1 |
| Ben Romdhane, T | 1 |
| Jendoubi-Ayed, S | 1 |
| Bardi, R | 1 |
| Abderrahim, E | 1 |
| Ben Abdallah, T | 1 |
| Ayed, K | 1 |
| Zhou, XJ | 1 |
| Swan, S | 1 |
| Smith, WB | 1 |
| Marbury, TC | 1 |
| Dubuc-Patrick, G | 1 |
| Chao, GC | 1 |
| Brown, NA | 1 |
| Langhoff, E | 1 |
| Ladefoged, J | 2 |
| Lewin, E | 1 |
| Brandi, L | 1 |
| Olgaard, K | 1 |
| Shurtz-Swirski, R | 1 |
| Kristal, B | 1 |
| Shkolnik, T | 1 |
| Weissman, I | 1 |
| Shapiro, G | 1 |
| Shasha, SM | 1 |
| Vamvakas, S | 1 |
| Bahner, U | 1 |
| Becker, P | 1 |
| Steinle, A | 1 |
| Götz, R | 1 |
| Heidland, A | 1 |
| Yu, JZ | 1 |
| Bondy, GP | 1 |
| Allard, MF | 1 |
| Thompson, CR | 1 |
| Levin, A | 1 |
| McManus, BM | 1 |
| Makropoulos, W | 1 |
| Kocher, K | 1 |
| Heintz, B | 1 |
| Schwarz, ER | 1 |
| Mertens, PR | 1 |
| Stefanidis, I | 1 |
| Jankowski, J | 1 |
| Hagemann, J | 1 |
| Yoon, MS | 1 |
| van der Giet, M | 1 |
| Stephan, N | 1 |
| Zidek, W | 1 |
| Schlüter, H | 1 |
| Tepel, M | 1 |
| Moe, SM | 1 |
| Zekonis, M | 1 |
| Harezlak, J | 1 |
| Ambrosius, WT | 1 |
| Gassensmith, CM | 1 |
| Murphy, CL | 1 |
| Russell, RR | 1 |
| Batiuk, TD | 1 |
| Vonend, O | 1 |
| Oberhauser, V | 1 |
| von Kügelgen, I | 1 |
| Apel, TW | 1 |
| Amann, K | 1 |
| Ritz, E | 2 |
| Rump, LC | 1 |
| Frei, E | 1 |
| Korz, R | 1 |
| Naber, A | 1 |
| Essers, U | 1 |
| Lee, MJ | 1 |
| Roth, SI | 1 |
| Hirano, T | 1 |
| Toyoshima, Y | 1 |
| Oka, K | 1 |
| Tamaki, T | 1 |
| Kozaki, M | 1 |
| Alexiewicz, JM | 1 |
| Klinger, M | 1 |
| Pitts, TO | 1 |
| Gaciong, Z | 1 |
| Linker-Israeli, M | 1 |
| Massry, SG | 1 |
| Klotz, LH | 1 |
| Kulkarni, C | 1 |
| Mills, G | 1 |
| Houghton, DC | 1 |
| English, J | 1 |
| Bennett, WM | 1 |
| Pauly, JL | 1 |
| Han, T | 1 |
| Varkarakis, MJ | 1 |
| Sokal, JE | 1 |
| Sampson, D | 1 |
| Murphy, GP | 1 |
| Häyry, P | 1 |
| Lalla, M | 1 |
| Pasternack, A | 1 |
| Virolainen, M | 1 |
| Raskova, J | 1 |
| Morrison, AB | 1 |
| Hunt, P | 1 |
| Scott, D | 1 |
| Trotter, S | 1 |
| Atkins, R | 1 |
| Wiktor, Z | 1 |
| Szewczyk, Z | 1 |
| Nakhla, LS | 1 |
| Goggin, MJ | 1 |
| Nelson, DS | 1 |
| Penrose, JM | 1 |
| Hayahara, N | 1 |
| Krempien, B | 1 |
| Schrecker, K | 1 |
| Wanke, M | 1 |
| Vichi, FL | 1 |
| Earle, DP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Telbivudine on Renal Function and Proteinuria in Patients With Chronic Hepatitis B Infection and Chronic Kidney Diseases[NCT02049736] | 0 participants (Actual) | Interventional | 2013-12-31 | Withdrawn (stopped due to unable to recruit patients) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thymidine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Methotrexate revisited.
Topics: Adolescent; Adult; Alkalies; Aminopterin; Animals; Bone Marrow; Bone Neoplasms; Drug Therapy, Combin | 1976 |
3 trials available for thymidine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Pharmacokinetics of telbivudine in subjects with various degrees of renal impairment.
Topics: Adolescent; Adult; Aged; Female; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Function T | 2007 |
Urinary thymidine glycol as a biomarker for oxidative stress after kidney transplantation.
Topics: Adult; Biomarkers; Chromatography, High Pressure Liquid; Follow-Up Studies; Graft Rejection; Graft S | 2000 |
A placebo-controlled trial to evaluate immunomodulatory effects of paricalcitol.
Topics: Adult; B-Lymphocytes; Calcitriol; Calcium; Double-Blind Method; Ergocalciferols; Female; Humans; Imm | 2001 |
24 other studies available for thymidine and Kidney Failure, Chronic
| Article | Year |
|---|---|
The PTPN22 C1858T (R620W) functional polymorphism in kidney transplantation.
Topics: Adult; Amino Acid Substitution; Chromosome Mapping; Chromosomes, Human, Pair 1; Cytosine; DNA; Femal | 2009 |
Cellular immunity in renal failure: depression of lymphocyte transformation by uraemia and methylprednisolone. Intra-individual consistency of lymphocyte responses to the in vitro suppressive effect of steroid.
Topics: Adult; Female; Humans; Immune Tolerance; Immunity, Cellular; Kidney Failure, Chronic; Lymphocyte Act | 1984 |
Parathyroid hormone dependent T cell proliferation in uremic rats.
Topics: Animals; Cell Division; Kidney Failure, Chronic; Kidney Transplantation; Male; Parathyroid Hormone; | 1993 |
Short-term effect of erythropoietin on T-cell mitogenic proliferation in chronic renal failure patients.
Topics: Adjuvants, Immunologic; Cell Division; Erythropoietin; Female; Hemoglobins; Humans; Kidney Failure, | 1996 |
Impairment of DNA repair in the course of long-term hemodialysis and under cyclosporine immunosuppression after renal transplantation.
Topics: Aged; Analysis of Variance; Cells, Cultured; Creatinine; Cyclosporine; DNA Damage; DNA Repair; Femal | 1996 |
Serum from patients with chronic renal insufficiency alters growth characteristics and ANP mRNA expression of adult rat cardiac myocytes.
Topics: Animals; Atrial Natriuretic Factor; Cell Division; Cells, Cultured; Gene Expression; Growth Substanc | 1996 |
Increased vascular growth in hemodialysis patients induced by platelet-derived diadenosine polyphosphates.
Topics: Animals; Blood Platelets; Cell Division; Cells, Cultured; Dinucleoside Phosphates; Female; Humans; K | 2001 |
ATP release in human kidney cortex and its mitogenic effects in visceral glomerular epithelial cells.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Brimonidine Tartrate; Cell Division; Cells, Cultu | 2002 |
[Spontaneous lymphocyte transformation in chronic renal insufficiency (author's transl)].
Topics: Blood Urea Nitrogen; Cells, Cultured; Creatinine; Culture Media; DNA; Hemoglobinometry; Humans; Kidn | 1975 |
Effect of calcium and magnesium on deoxyribonucleic acid synthesis in rat parathyroid glands in vitro.
Topics: Animals; Autoradiography; Calcium; Deoxycytidine; DNA; Humans; Hydroxyurea; Hyperplasia; Kidney; Kid | 1975 |
Promotion of lymphocyte blastogenesis by hemodialysate of chronic renal failure.
Topics: Allopurinol; Anabolic Agents; Androstanols; Calcitriol; Cells, Cultured; Concanavalin A; Creatinine; | 1992 |
Parathyroid hormone inhibits B cell proliferation: implications in chronic renal failure.
Topics: Adult; Aged; B-Lymphocytes; Cell Division; Colforsin; Cyclic AMP; Female; Humans; Hyperparathyroidis | 1990 |
End stage renal disease serum contains a specific renal cell growth factor.
Topics: Calcium Radioisotopes; Carcinoma, Renal Cell; Cell Division; Cells, Cultured; Growth Substances; Hum | 1991 |
Chronic tubulointerstitial nephritis and renal insufficiency associated with long-term "subtherapeutic" gentamicin.
Topics: Animals; Autoradiography; Gentamicins; Glomerular Filtration Rate; Inulin; Kidney Failure, Chronic; | 1988 |
Leukocyte (3H) thymidine uptake in short-term whole-blood cultures of human and canine renal allograft recipients.
Topics: Animals; Azathioprine; Cadaver; Dogs; Graft Rejection; Hodgkin Disease; Humans; Immunity, Cellular; | 1973 |
Proliferation of white blood cells in the blood of human renal allograft recipients. Lack of correlation with acute rejection episodes.
Topics: Adult; Autoradiography; Azathioprine; Cell Division; Child; DNA; Erythrocytes; Female; Graft Rejecti | 1972 |
Immunological responses to sheep red blood cells in experimentally induced chronic uremia of rats.
Topics: Animals; Antibodies; Antibody Formation; Antibody-Producing Cells; Antigens; Blood Urea Nitrogen; Ch | 1973 |
A simple method of measuring host immune rejection response after renal transplantation.
Topics: Cholecystectomy; Graft Rejection; Humans; Kidney Failure, Chronic; Kidney Transplantation; Lymphocyt | 1973 |
Effect of radon inhalation on the reactivity of lymphocytes.
Topics: Carbon Isotopes; DNA; Glomerulonephritis; Humans; In Vitro Techniques; Kidney Failure, Chronic; Lect | 1972 |
Lymphocyte transformation in chronic renal failure.
Topics: Age Factors; Chronic Disease; Humans; Kidney Failure, Chronic; Lectins; Lymphocyte Activation; Lymph | 1973 |
Macromolecular inhibitor of lymphocyte transformation in serum from patients with chronic renal failure.
Topics: Adolescent; Adult; Chronic Disease; Depression, Chemical; Female; Humans; Kidney Failure, Chronic; L | 1973 |
[Studies on the immunological response in patients with terminal renal failure (author's transl)].
Topics: Adult; Female; Humans; Kidney Failure, Chronic; Lectins; Lymphocyte Activation; Lymphocytes; Male; M | 1973 |
[Changes in the gastric mucosa in experimental uremia. Behavior of the parietal cells in the gastric mucosa of uremic mice. An autoradiographic study].
Topics: Animals; Autoradiography; Cell Division; Disease Models, Animal; Gastric Mucosa; Injections, Intrape | 1971 |
Renal hypertrophy factor in serum of nephrectomized rats, with observations on species specificity.
Topics: Animals; Dogs; Humans; Hypertrophy; Injections; Kidney; Kidney Failure, Chronic; Male; Nephrectomy; | 1970 |