thymidine has been researched along with Kidney Diseases in 39 studies
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the potential effects of telbivudine (LdT) and entecavir (ETV) on renal function in patients with chronic hepatitis B (CHB), we performed a meta-analysis of the relevant data available on these agents to evaluate their effects on the estimated glomerular filtration rate (eGFR) during treatment." | 4.93 | Potential effects of telbivudine and entecavir on renal function: a systematic review and meta-analysis. ( Cai, S; Li, Z; Peng, J; Wu, X; Xue, X; Zeng, J; Zheng, C, 2016) |
| "Twenty patients who received high-dose methotrexate for osteosarcoma (n = 11), lymphoid cancers (n = 8), and gastric cancer (n = 1) developed nephrotoxicity (median serum creatinine, 3." | 3.69 | Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction. ( Adamson, PC; Balis, FM; Montello, MJ; Murphy, RF; O'Brien, M; Sorensen, JM; Widemann, BC, 1997) |
| "Telbivudine was well tolerated by all subjects." | 2.73 | Pharmacokinetics of telbivudine in subjects with various degrees of renal impairment. ( Brown, NA; Chao, GC; Dubuc-Patrick, G; Marbury, TC; Smith, WB; Swan, S; Zhou, XJ, 2007) |
| "Increased risk of lactic acidosis has also been described for those with impaired liver and renal function taking entecavir." | 2.50 | Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment. ( Fung, J; Lai, CL; Seto, WK; Yuen, MF, 2014) |
| "Thymidine has been available for clinical research as a rescue agent since 1978 under sponsorship of the Division of Cancer Treatment, National Cancer Institute." | 2.38 | Clinical use of thymidine as a rescue agent from methotrexate toxicity. ( Christian, MC; Grem, JL; King, SA; Sorensen, JM, 1991) |
| "Telbivudine is a new nucleoside analog indicated for the treatment of chronic hepatitis B infection." | 1.35 | Population pharmacokinetics of telbivudine and determination of dose adjustment for patients with renal impairment. ( Farrell, C; Ke, J; Mayers, DL; Pentikis, HS; Sallas, WM; Zhou, XJ, 2009) |
| " Tissue injury was measured during the dosing regimen (0, 1, 7, 14, and 30 days) and over a time course of 24-96h after the last dose (30 days)." | 1.34 | Impact of repeated exposure on toxicity of perchloroethylene in Swiss Webster mice. ( Latendresse, JR; Mehendale, HM; Mumtaz, MM; Philip, BK, 2007) |
| " We conclude that daptomycin is safe and protects kidney cells from tobramycin-induced nephrotoxicity." | 1.28 | Effects of daptomycin and vancomycin on tobramycin nephrotoxicity in rats. ( Beauchamp, D; Bergeron, MG; Gourde, P; Pellerin, M; Pettigrew, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (46.15) | 18.7374 |
| 1990's | 8 (20.51) | 18.2507 |
| 2000's | 7 (17.95) | 29.6817 |
| 2010's | 6 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fung, J | 1 |
| Seto, WK | 1 |
| Lai, CL | 1 |
| Yuen, MF | 1 |
| Tsai, MC | 1 |
| Chen, CH | 1 |
| Tseng, PL | 1 |
| Hung, CH | 1 |
| Chiu, KW | 1 |
| Wang, JH | 1 |
| Lu, SN | 1 |
| Lee, CM | 1 |
| Chang, KC | 1 |
| Yen, YH | 1 |
| Lin, MT | 1 |
| Chou, YP | 1 |
| Hu, TH | 1 |
| Thu, AM | 1 |
| Poovorawan, K | 1 |
| Kittitrakul, C | 1 |
| Nontprasert, A | 1 |
| Sriboonvorakul, N | 1 |
| Phumratanaprapin, W | 1 |
| Tangkijvanich, P | 1 |
| Leowattana, W | 1 |
| Wilairatana, P | 1 |
| Wu, X | 1 |
| Cai, S | 1 |
| Li, Z | 1 |
| Zheng, C | 1 |
| Xue, X | 1 |
| Zeng, J | 1 |
| Peng, J | 1 |
| Zhou, XJ | 2 |
| Ke, J | 1 |
| Sallas, WM | 1 |
| Farrell, C | 1 |
| Mayers, DL | 1 |
| Pentikis, HS | 1 |
| Widemann, BC | 2 |
| Balis, FM | 2 |
| Kim, A | 1 |
| Boron, M | 1 |
| Jayaprakash, N | 1 |
| Shalabi, A | 1 |
| O'Brien, M | 2 |
| Eby, M | 1 |
| Cole, DE | 1 |
| Murphy, RF | 2 |
| Fox, E | 1 |
| Ivy, P | 1 |
| Adamson, PC | 2 |
| U Rehman, M | 1 |
| Sultana, S | 1 |
| Dobrovolsky, VN | 1 |
| Bucci, T | 1 |
| Heflich, RH | 1 |
| Desjardins, J | 1 |
| Richardson, FC | 1 |
| LOWENSTEIN, LM | 1 |
| STERN, A | 1 |
| COOPER, IA | 2 |
| FIRKIN, BG | 2 |
| REITER, RJ | 1 |
| MCCREIGHT, CE | 1 |
| BURY, HP | 1 |
| CRANE, WA | 1 |
| DUTTA, LP | 1 |
| Kaur, G | 1 |
| Lone, IA | 1 |
| Athar, M | 1 |
| Alam, MS | 1 |
| Philip, BK | 1 |
| Mumtaz, MM | 1 |
| Latendresse, JR | 1 |
| Mehendale, HM | 1 |
| Swan, S | 1 |
| Smith, WB | 1 |
| Marbury, TC | 1 |
| Dubuc-Patrick, G | 1 |
| Chao, GC | 1 |
| Brown, NA | 1 |
| Hansson, CG | 1 |
| Abelson, HT | 1 |
| Fosburg, MT | 1 |
| Beardsley, GP | 1 |
| Goorin, AM | 1 |
| Gorka, C | 1 |
| Link, M | 1 |
| Link, D | 1 |
| Beauchamp, D | 6 |
| Thériault, G | 1 |
| Grenier, L | 4 |
| Gourde, P | 4 |
| Perron, S | 1 |
| Bergeron, Y | 2 |
| Fontaine, L | 1 |
| Bergeron, MG | 6 |
| Thibault, N | 1 |
| Simard, M | 3 |
| Lin, L | 2 |
| Labrecque, G | 2 |
| Yoshiyama, Y | 1 |
| Morin, NJ | 1 |
| Sorensen, JM | 2 |
| Montello, MJ | 1 |
| Thomas, S | 1 |
| Vanuystel, J | 1 |
| Gruden, G | 1 |
| Rodríguez, V | 1 |
| Burt, D | 1 |
| Gnudi, L | 1 |
| Hartley, B | 1 |
| Viberti, G | 1 |
| Liu, XH | 1 |
| Aigner, A | 1 |
| Wellstein, A | 1 |
| Ray, PE | 1 |
| Krakauer, KA | 1 |
| Torrey, SB | 1 |
| Zurier, RB | 1 |
| Grem, JL | 1 |
| King, SA | 1 |
| Christian, MC | 1 |
| Pellerin, M | 1 |
| Pettigrew, M | 1 |
| Auclair, P | 1 |
| Tardif, D | 1 |
| Choie, DD | 1 |
| Richter, GW | 1 |
| Borel, Y | 1 |
| Lewis, RM | 1 |
| Stollar, BD | 1 |
| Virolainen, M | 1 |
| Lalla, M | 1 |
| Pasternack, A | 1 |
| Wasastjerna, C | 1 |
| Häyry, P | 1 |
| Pound, AW | 1 |
| Horn, L | 1 |
| Lawson, TA | 1 |
| Helpap, B | 1 |
| Breining, H | 1 |
| Minderjahn, A | 1 |
| Lymberopoulos, S | 1 |
| Schwarz, H | 1 |
| Janicki, RH | 1 |
| Janicki, R | 1 |
| Lingis, J | 1 |
| Pincus, T | 1 |
| Schur, PH | 1 |
| Rose, JA | 1 |
| Decker, JL | 1 |
| Talal, N | 1 |
| Noltenius, H | 1 |
| Achenbach, H | 1 |
| Oehlert, W | 1 |
| Schellhas, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Telbivudine on Renal Function and Proteinuria in Patients With Chronic Hepatitis B Infection and Chronic Kidney Diseases[NCT02049736] | 0 participants (Actual) | Interventional | 2013-12-31 | Withdrawn (stopped due to unable to recruit patients) | |||
| A Trial of Carboxypeptidase-G2 (CPDG2) and Thymidine for the Management of Patients With Methotrexate Toxicity and Renal Dysfunction[NCT00001298] | Phase 1 | 10 participants | Interventional | 1992-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for thymidine and Kidney Diseases
| Article | Year |
|---|---|
Extrahepatic effects of nucleoside and nucleotide analogues in chronic hepatitis B treatment.
Topics: Acidosis, Lactic; Adenine; Administration, Oral; Antiviral Agents; Arabinofuranosyluracil; Dose-Resp | 2014 |
Potential effects of telbivudine and entecavir on renal function: a systematic review and meta-analysis.
Topics: Antiviral Agents; China; Guanine; Hepatitis B, Chronic; Humans; Kidney; Kidney Diseases; Kidney Func | 2016 |
Clinical use of thymidine as a rescue agent from methotrexate toxicity.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Kidney; Kidney Diseases; Male; Meta-Analysis as Topi | 1991 |
1 trial available for thymidine and Kidney Diseases
| Article | Year |
|---|---|
Pharmacokinetics of telbivudine in subjects with various degrees of renal impairment.
Topics: Adolescent; Adult; Aged; Female; Humans; Kidney Diseases; Kidney Failure, Chronic; Kidney Function T | 2007 |
35 other studies available for thymidine and Kidney Diseases
| Article | Year |
|---|---|
Comparison of renal safety and efficacy of telbivudine, entecavir and tenofovir treatment in chronic hepatitis B patients: real world experience.
Topics: Adult; Aged; Aged, 80 and over; Antiviral Agents; Drug-Related Side Effects and Adverse Reactions; F | 2016 |
Nephrotoxicity caused by oral antiviral agents in patients with chronic hepatitis B treated in a hospital for tropical diseases in Thailand.
Topics: Adenine; Adult; Antiviral Agents; Creatinine; Female; Follow-Up Studies; Guanine; Hepatitis B, Chron | 2015 |
Population pharmacokinetics of telbivudine and determination of dose adjustment for patients with renal impairment.
Topics: Adult; Aged; Antiviral Agents; Biological Availability; Female; Humans; Kidney Diseases; Male; Middl | 2009 |
Glucarpidase, leucovorin, and thymidine for high-dose methotrexate-induced renal dysfunction: clinical and pharmacologic factors affecting outcome.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Drug Administration Schedule; D | 2010 |
Attenuation of oxidative stress, inflammation and early markers of tumor promotion by caffeic acid in Fe-NTA exposed kidneys of Wistar rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Caffeic Acids; Creatinine; DNA; Environmental Pollutants | 2011 |
Mice deficient for cytosolic thymidine kinase gene develop fatal kidney disease.
Topics: Animals; Arteritis; Breeding; Cytosol; Female; Genotype; Hypoxanthine Phosphoribosyltransferase; Kid | 2003 |
SERUM FACTOR IN RENAL COMPENSATORY HYPERPLASIA.
Topics: Blood; Cell Division; Hyperplasia; Hypertrophy; Kidney; Kidney Diseases; Liver; Nephrectomy; Rats; R | 1963 |
THE PRESENCE OF DEOXYRIBONUCLEIC ACID (DNA) SYNTHESIZING CELLS IN PATIENTS WITH REFRACTORY ANEMIA.
Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Refractory; Autoradiography; DNA; Geriatrics; H | 1964 |
A STUDY OF INDUCED RENAL HYPERPLASIA USING AUTORADIOGRAPHY.
Topics: Autoradiography; Hyperplasia; Kidney; Kidney Diseases; Rats; Research; Thymidine; Tritium | 1965 |
CELL PROLIFERATION IN COMPENSATORY RENAL GROWTH.
Topics: Adrenocorticotropic Hormone; Aldosterone; Autoradiography; Benz(a)Anthracenes; Carcinogens; Cell Div | 1965 |
DEOXYRIBONUCLEIC ACID SYNTHESIZING CELLS IN THE PERIPHERAL BLOOD OF PATIENTS WITH "AUTO-IMMUNE" DISORDERS.
Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Rheumatoid; Autoimmune Diseases; | 1965 |
Protective effect of Didymocarpus pedicellata on ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and hyperproliferative response.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Body Weight; Cell Proliferation; Creatinine; DNA; Ferric | 2007 |
Impact of repeated exposure on toxicity of perchloroethylene in Swiss Webster mice.
Topics: Alanine Transaminase; Animals; Blood Urea Nitrogen; Chemical and Drug Induced Liver Injury; Cytochro | 2007 |
The parathyroids in corticosteroid-treated male rats.
Topics: Adrenal Glands; Alkalosis; Animals; Autoradiography; Body Weight; Calcium; Cell Division; Cell Nucle | 1967 |
Methotrexate-induced renal impairment: clinical studies and rescue from systemic toxicity with high-dose leucovorin and thymidine.
Topics: Adolescent; Adult; Child; Creatinine; Dose-Response Relationship, Drug; Drug Therapy, Combination; G | 1983 |
Ceftriaxone protects against tobramycin nephrotoxicity.
Topics: Animals; beta-Galactosidase; Ceftriaxone; Creatinine; Drug Interactions; Enzymes; Female; Kidney Cor | 1994 |
Attenuation by daptomycin of gentamicin-induced experimental nephrotoxicity.
Topics: Animals; Creatinine; Daptomycin; DNA; Female; Gentamicins; Immunohistochemistry; Kidney; Kidney Cort | 1994 |
Temporal changes of pharmacokinetics, nephrotoxicity, and subcellular distribution of tobramycin in rats.
Topics: Acetylglucosamine; Acetylglucosaminidase; Animals; Body Weight; Female; Immunohistochemistry; Kidney | 1994 |
Temporal variation in nephrotoxicity of low doses of isepamicin in rats.
Topics: Animals; Anti-Bacterial Agents; Body Weight; Circadian Rhythm; Gentamicins; Immunohistochemistry; In | 1996 |
Carboxypeptidase-G2, thymidine, and leucovorin rescue in cancer patients with methotrexate-induced renal dysfunction.
Topics: Adolescent; Adult; Antidotes; Antimetabolites, Antineoplastic; Carboxypeptidases; Child; Child, Pres | 1997 |
Vascular endothelial growth factor receptors in human mesangium in vitro and in glomerular disease.
Topics: Aged; Cell Count; Cell Division; Cells, Cultured; Endothelial Growth Factors; Glomerular Mesangium; | 2000 |
Up-regulation of a fibroblast growth factor binding protein in children with renal diseases.
Topics: AIDS-Associated Nephropathy; Animals; Base Sequence; Carrier Proteins; Case-Control Studies; Cells, | 2001 |
Prostaglandin E1 treatment of NZB/W mice. III. Preservation of spleen cell concentrations and mitogen-induced proliferative responses.
Topics: Animals; B-Lymphocytes; Female; Kidney Diseases; Lymphocyte Activation; Mice; Mice, Inbred A; Mice, | 1978 |
Effects of daptomycin and vancomycin on tobramycin nephrotoxicity in rats.
Topics: Animals; Daptomycin; Drug Interactions; Female; Kidney Cortex; Kidney Diseases; Kidney Medulla; Pept | 1990 |
Prolonged endotoxemia enhances the renal injuries induced by gentamicin in rats.
Topics: Animals; Body Weight; Drug Synergism; Endotoxins; Female; Gentamicins; Hematocrit; Kidney; Kidney Co | 1990 |
Cell proliferation in rat kidneys after prolonged treatment with lead.
Topics: Animals; Autoradiography; Cell Division; Cell Nucleus; DNA; DNA Replication; Epithelial Cells; Epith | 1972 |
Prevention of murine lupus nephritis by carrier-dependent induction of immunologic tolerance to denatured DNA.
Topics: Adenosine; Age Factors; Animals; Antibodies, Antinuclear; Antibody Formation; Carrier Proteins; Cyto | 1973 |
DNA-synthesizing myeloid and lymphoid cells in the blood of haemodialysis patients and kidney graft recipients.
Topics: Autoradiography; Cell Division; Cell Nucleus; Cytoplasm; DNA; Glomerulonephritis; Graft Rejection; H | 1974 |
Decreased toxicity of dimethylnitrosamine in rats after treatment with carbon tetrachloride.
Topics: Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Dimethylamines; DNA; Kidney; | 1973 |
[Wound healing of kidney after cryonecrosis. Autoradiographic investigations with 3H-thymidine on rats (authors transl)].
Topics: Animals; Autoradiography; Fibroblasts; Freezing; Kidney; Kidney Diseases; Kidney Tubules; Leukocytes | 1974 |
Renal invasion by E. coli via a mucosal lesion of the sigmoid colon: a demonstration utilizing methods of autoradiography and group-specific serologic typing.
Topics: Animals; Anti-Bacterial Agents; Autoradiography; Colon; Colon, Sigmoid; Culture Techniques; Dogs; Es | 1968 |
Renal adaptation during chronic NH4Cl acidosis in the rat: no role for hyperplasia.
Topics: Acidosis; Adaptation, Physiological; Ammonium Chloride; Animals; Cell Division; DNA; Functional Late | 1970 |
Unabated renal hypertrophy in uninephrectomized rats treated with hydroxyurea.
Topics: Animals; Colorimetry; DNA; Hydroxyurea; Hyperplasia; Hypertrophy; Kidney; Kidney Diseases; Male; Nep | 1970 |
Measurement of serum DNA-binding activity in systemic lupus erythematosus.
Topics: Adolescent; Aged; Antigen-Antibody Reactions; Autoantibodies; Carbon Isotopes; Chemical Precipitatio | 1969 |
[Experimental kidney hypertrophy after unilateral nephrectomy in rats. Studies with thymidine- H3].
Topics: Animals; Autoradiography; Hypertrophy; Kidney Diseases; Nephrectomy; Postoperative Complications; Ra | 1965 |