thymidine has been researched along with Hypertension, Pulmonary in 15 studies
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The appetite suppressant dexfenfluramine, which inhibits neuronal 5-HT uptake and elevates plasma 5-HT levels, has been associated with an increase in the relative risk of developing primary pulmonary hypertension." | 7.71 | Dexfenfluramine-associated changes in 5-hydroxytryptamine transporter expression and development of hypoxic pulmonary hypertension in rats. ( Adnot, S; Eddahibi, S; Frisdal, E; Hamon, M; Levame, M; Raffestin, B, 2001) |
| "Previously, we have shown that the protection provided by 2-difluoromethylornithine (DFMO) against the development of monocrotaline (MCT)-induced pulmonary hypertension (PH) is associated with inhibition of polyamine biosynthesis in the lungs of MCT-treated rats." | 7.68 | Inhibition of deoxyribonucleic acid synthesis by difluoromethylornithine. Role of polyamine metabolism in monocrotaline-induced pulmonary hypertension. ( Hacker, AD, 1992) |
| " By autoradiographic techniques, after injection of 3H-thymidine into rats fed Crotalaria for 3, 7, 14, 21, 28, or 35 days, the contribution of hyperplasia to these changes has been assessed at two levels of the pulmonary artery--the hilum and the periphery." | 7.66 | Crotalaria-induced pulmonary hypertension. Uptake of 3H-thymidine by the cells of the pulmonary circulation and alveolar walls. ( Meyrick, BO; Reid, LM, 1982) |
| "Azaindole-1 treatment resulted in a decreased immunoreactivity for phospho-myosin phosphatase target subunit 1 and proliferating cell nuclear antigen in pulmonary vessels of MCT-injected rats, suggesting an impaired ROCK activity and reduced proliferating cells." | 5.36 | Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension. ( Dahal, BK; Ghofrani, HA; Grimminger, F; Kast, R; Kosanovic, D; Lai, YJ; Pamarthi, PK; Schermuly, RT; Schirok, H; Seeger, W; Stasch, JP; Sydykov, A; Weissmann, N, 2010) |
| "The appetite suppressant dexfenfluramine, which inhibits neuronal 5-HT uptake and elevates plasma 5-HT levels, has been associated with an increase in the relative risk of developing primary pulmonary hypertension." | 3.71 | Dexfenfluramine-associated changes in 5-hydroxytryptamine transporter expression and development of hypoxic pulmonary hypertension in rats. ( Adnot, S; Eddahibi, S; Frisdal, E; Hamon, M; Levame, M; Raffestin, B, 2001) |
| "Monocrotaline (MCT) causes chronic pulmonary hypertension associated with pulmonary vascular thickening in rats." | 3.69 | [Lung 3H-thymidine incorporation in monocrotaline (MCT)-treated rats--role of platelet-activating factor (PAF)]. ( Ashino, Y; Fujimura, S; Hoshikawa, Y; Nishimura, T; Noda, M; Ono, S; Tabata, S; Tanita, T; Ueda, S, 1994) |
| "Increased production of endothelin-1 (ET-1) has been detected in lungs of fawn-hooded rats (FHR) with idiopathic pulmonary hypertension." | 3.69 | Overexpression of endothelin-1 and enhanced growth of pulmonary artery smooth muscle cells from fawn-hooded rats. ( Dempsey, EC; Panos, RJ; Ruff, LJ; Stelzner, TJ; Webb, S; Zamora, MR, 1996) |
| "We recently reported that platelet-activating factor (PAF) levels increased in lung tissue after 1 subcutaneous injection of monocrotaline (MCT) (which causes lung injury), and, further, that treatment with PAF antagonists reduced pulmonary hypertension in this chronic lung injury rat model [15]." | 3.68 | PAF receptor blockade inhibits lung vascular changes in the rat monocrotaline model. ( Ono, S; Voelkel, NF, 1992) |
| "Previously, we have shown that the protection provided by 2-difluoromethylornithine (DFMO) against the development of monocrotaline (MCT)-induced pulmonary hypertension (PH) is associated with inhibition of polyamine biosynthesis in the lungs of MCT-treated rats." | 3.68 | Inhibition of deoxyribonucleic acid synthesis by difluoromethylornithine. Role of polyamine metabolism in monocrotaline-induced pulmonary hypertension. ( Hacker, AD, 1992) |
| " By autoradiographic techniques, after injection of 3H-thymidine into rats fed Crotalaria for 3, 7, 14, 21, 28, or 35 days, the contribution of hyperplasia to these changes has been assessed at two levels of the pulmonary artery--the hilum and the periphery." | 3.66 | Crotalaria-induced pulmonary hypertension. Uptake of 3H-thymidine by the cells of the pulmonary circulation and alveolar walls. ( Meyrick, BO; Reid, LM, 1982) |
| "Azaindole-1 treatment resulted in a decreased immunoreactivity for phospho-myosin phosphatase target subunit 1 and proliferating cell nuclear antigen in pulmonary vessels of MCT-injected rats, suggesting an impaired ROCK activity and reduced proliferating cells." | 1.36 | Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension. ( Dahal, BK; Ghofrani, HA; Grimminger, F; Kast, R; Kosanovic, D; Lai, YJ; Pamarthi, PK; Schermuly, RT; Schirok, H; Seeger, W; Stasch, JP; Sydykov, A; Weissmann, N, 2010) |
| "Chronic pulmonary hypertension is associated with extensive structural remodeling of the pulmonary arterial bed." | 1.28 | Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension. ( Brigham, KL; Lyons, RM; Meyrick, B; Moses, HL; Perkett, EA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (20.00) | 18.7374 |
| 1990's | 7 (46.67) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dahal, BK | 1 |
| Kosanovic, D | 1 |
| Pamarthi, PK | 1 |
| Sydykov, A | 1 |
| Lai, YJ | 1 |
| Kast, R | 1 |
| Schirok, H | 1 |
| Stasch, JP | 1 |
| Ghofrani, HA | 1 |
| Weissmann, N | 1 |
| Grimminger, F | 1 |
| Seeger, W | 1 |
| Schermuly, RT | 1 |
| Mortimer, HJ | 1 |
| Peacock, AJ | 2 |
| Kirk, A | 1 |
| Welsh, DJ | 2 |
| Meyrick, BO | 1 |
| Reid, LM | 1 |
| Ono, S | 2 |
| Tanita, T | 1 |
| Ashino, Y | 1 |
| Noda, M | 1 |
| Tabata, S | 1 |
| Hoshikawa, Y | 1 |
| Ueda, S | 1 |
| Nishimura, T | 1 |
| Fujimura, S | 1 |
| Zamora, MR | 1 |
| Stelzner, TJ | 1 |
| Webb, S | 1 |
| Panos, RJ | 1 |
| Ruff, LJ | 1 |
| Dempsey, EC | 1 |
| Scott, P | 1 |
| Plevin, R | 1 |
| Wadsworth, R | 1 |
| Eddahibi, S | 3 |
| Fabre, V | 1 |
| Boni, C | 1 |
| Martres, MP | 1 |
| Raffestin, B | 3 |
| Hamon, M | 3 |
| Adnot, S | 3 |
| Frisdal, E | 1 |
| Levame, M | 1 |
| Morrell, NW | 1 |
| Yang, X | 1 |
| Upton, PD | 1 |
| Jourdan, KB | 1 |
| Morgan, N | 1 |
| Sheares, KK | 1 |
| Trembath, RC | 1 |
| Humbert, M | 1 |
| Fadel, E | 1 |
| Darmon, M | 1 |
| Capron, F | 1 |
| Simonneau, G | 1 |
| Dartevelle, P | 1 |
| Voelkel, NF | 1 |
| Hacker, AD | 1 |
| Perkett, EA | 1 |
| Lyons, RM | 1 |
| Moses, HL | 1 |
| Brigham, KL | 1 |
| Meyrick, B | 1 |
| Jones, R | 1 |
| Adler, C | 1 |
| Farber, F | 1 |
| Gonzalez-Lavin, L | 1 |
| O'Connell, TX | 1 |
15 other studies available for thymidine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension.
Topics: Animals; Azabicyclo Compounds; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Hemody | 2010 |
p38 MAP kinase: essential role in hypoxia-mediated human pulmonary artery fibroblast proliferation.
Topics: Blotting, Western; Cell Hypoxia; Cell Proliferation; Fibroblasts; Gene Expression Regulation; Humans | 2007 |
Crotalaria-induced pulmonary hypertension. Uptake of 3H-thymidine by the cells of the pulmonary circulation and alveolar walls.
Topics: Animals; Autoradiography; Body Weight; Fabaceae; Hyperplasia; Hypertension, Pulmonary; Hypertrophy; | 1982 |
[Lung 3H-thymidine incorporation in monocrotaline (MCT)-treated rats--role of platelet-activating factor (PAF)].
Topics: Animals; Azepines; DNA; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Platelet Activating Fact | 1994 |
Overexpression of endothelin-1 and enhanced growth of pulmonary artery smooth muscle cells from fawn-hooded rats.
Topics: Animals; Blood Physiological Phenomena; Cell Division; Endothelin-1; Endothelins; Female; Hypertensi | 1996 |
Hypoxia enhances cellular proliferation and inositol 1,4, 5-triphosphate generation in fibroblasts from bovine pulmonary artery but not from mesenteric artery.
Topics: Analysis of Variance; Animals; Blood; Cattle; Cell Communication; Cell Division; Cells, Cultured; El | 1998 |
Induction of serotonin transporter by hypoxia in pulmonary vascular smooth muscle cells. Relationship with the mitogenic action of serotonin.
Topics: Animals; Carrier Proteins; Cell Division; Cell Hypoxia; Hypertension, Pulmonary; Lung; Male; Membran | 1999 |
Dexfenfluramine-associated changes in 5-hydroxytryptamine transporter expression and development of hypoxic pulmonary hypertension in rats.
Topics: Animals; Appetite Depressants; Carrier Proteins; Cell Hypoxia; Dexfenfluramine; Hypertension, Pulmon | 2001 |
Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins.
Topics: Activin Receptors; Adult; Binding, Competitive; Bone Morphogenetic Protein Receptors, Type II; Bone | 2001 |
Serotonin transporter overexpression is responsible for pulmonary artery smooth muscle hyperplasia in primary pulmonary hypertension.
Topics: Adolescent; Adult; Aged; Alleles; Carrier Proteins; Case-Control Studies; Cells, Cultured; Female; G | 2001 |
PAF receptor blockade inhibits lung vascular changes in the rat monocrotaline model.
Topics: Animals; Azepines; Blood Pressure; Hydroxyproline; Hypertension, Pulmonary; Lung; Male; Monocrotalin | 1992 |
Inhibition of deoxyribonucleic acid synthesis by difluoromethylornithine. Role of polyamine metabolism in monocrotaline-induced pulmonary hypertension.
Topics: Animals; Biogenic Polyamines; Blood Pressure; DNA; DNA Replication; Eflornithine; Hypertension, Pulm | 1992 |
Transforming growth factor-beta activity in sheep lung lymph during the development of pulmonary hypertension.
Topics: Animals; Biological Assay; Cell Division; Hypertension, Pulmonary; Lung; Lymph; Pulmonary Embolism; | 1990 |
Lung vascular cell proliferation in hyperoxic pulmonary hypertension and on return to air: [3H]thymidine pulse-labeling of intimal, medial, and adventitial cells in microvessels and at the hilum.
Topics: Air; Animals; Blood Vessels; Capillaries; Cell Division; Endothelium, Vascular; Hypertension, Pulmon | 1989 |
Mitral valve replacement with viable aortic homograft valves.
Topics: Adult; Anticoagulants; Aortic Valve; Autoradiography; Blood Pressure; Erythromycin; Female; Fibrobla | 1973 |