Page last updated: 2024-11-06

thymidine and HIV

thymidine has been researched along with HIV in 92 studies

HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.

Research Excerpts

Excerpt	Relevance	Reference
"Novel derivatives of the anti-HIV-1 agent, TSAO-T, bearing at the N-3 position alkylating groups or photoaffinity labels were prepared and evaluated for their anti-HIV activity."	7.74	Novel N-3 substituted TSAO-T derivatives: synthesis and anti-HIV-evaluation. ( Balzarini, J; Bonache, MC; Camarasa, MJ; Pérez-Pérez, MJ; Quesada, E; San-Félix, A; Sheen, CW; Sluis-Cremer, N, 2008)
"To evaluate whether an inter-individual variability in the activity of thymidine kinase (TK) and deoxycytidine kinase (dCK), which are involved in the first step of phosphorylation of some nucleoside analogues, exists in antiretroviral-naive, HIV-seropositive patients."	7.73	Thymidine kinase and deoxycytidine kinase activity in mononuclear cells from antiretroviral-naive HIV-infected patients. ( Antonelli, G; Antonelli, L; Butera, O; Gianotti, N; Girardi, E; Iaiani, G; Lazzarin, A; Mazzi, R; Parisi, SG; Turriziani, O, 2005)
"The novel 5-chloro-, 5-bromo-, and 5-iodo-derivatives of 3'-fluoro-2',3'-dideoxyuridine (FddUrd), designated FddCIUrd, FddBrUrd, and FddIUrd, respectively, have been synthesized and evaluated for their antiretrovirus activity against human immunodeficiency virus (HIV) and murine Moloney sarcoma virus."	7.67	5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine. ( Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R; Schols, D; Van Aerschot, A, 1989)
"The effect of 3'-azido-2',3'-dideoxythymidine (AZT) on the human immunodeficiency virus (HIV)-associated giant cell formation was studied in vitro."	7.67	Effect of 3'-azido-2',3'-dideoxythymidine (AZT) and neutralizing antibody on human immunodeficiency virus (HIV)-induced cytopathic effects: implication of giant cell formation for the spread of virus in vivo. ( Kobayashi, N; Matsuda, A; Nakashima, H; Tochikura, T; Ueda, T; Yamamoto, N, 1987)
"Six HIV-antigenaemic patients with AIDS or AIDS-related complex were studied to assess the effect of treatment with low-dose zidovudine (250 mg) in 6-hourly doses on HIV antigen (HIV-Ag) levels in cerebrospinal fluid (CSF)."	7.67	Decline of HIV antigen levels in cerebrospinal fluid during treatment with low-dose zidovudine. ( Cload, P; Danner, SA; de Gans, J; de Wolf, F; Derix, MM; Eeftinck Schattenkerk, JK; Goudsmit, J; Lange, JM; Ongerboer de Visser, BW, 1988)
"Among 16 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex studied serially, 12 had or developed antigenemia ranging from 16 to 3006 pg/mL in plasma."	6.66	Human immunodeficiency virus (HIV) antigenemia (p24) in the acquired immunodeficiency syndrome (AIDS) and the effect of treatment with zidovudine (AZT). ( Despotes, JC; Emeson, EE; Falk, LA; Jackson, GG; Knigge, M; Mack, D; Paul, DA; Rubenis, M, 1988)
"18 men with longstanding human immunodeficiency virus (HIV) antigenaemia but no symptoms received zidovudine in low-dose regimens (250 mg 6-hourly, 500 mg 6-hourly, or 500 mg 12-hourly) with or without acyclovir."	5.06	Effect of zidovudine on serum human immunodeficiency virus antigen levels in symptom-free subjects. ( Cload, P; Coutinho, RA; de Gans, J; de Wolf, F; Fiddian, AP; Goudsmit, J; Lange, JM; Schellekens, PT; van der Noordaa, J, 1988)
"During zidovudine and stavudine treatment, HIV-1 selects several mutations (thymidine-associated mutations, TAMs) in the reverse transcriptase gene that confer high- and moderate-levels of resistance, respectively, to these nucleoside reverse transcriptase inhibitors (NRTIs)."	4.82	Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs). ( Goldschmidt, V; Marquet, R, 2004)
"Zidovudine is a potent in vitro inhibitor of human immunodeficiency virus (HIV) with varying efficacy against other retroviruses."	4.77	Spectrum of antiviral activity and mechanism of action of zidovudine. An overview. ( Barry, DW; Furman, PA, 1988)
"Novel derivatives of the anti-HIV-1 agent, TSAO-T, bearing at the N-3 position alkylating groups or photoaffinity labels were prepared and evaluated for their anti-HIV activity."	3.74	Novel N-3 substituted TSAO-T derivatives: synthesis and anti-HIV-evaluation. ( Balzarini, J; Bonache, MC; Camarasa, MJ; Pérez-Pérez, MJ; Quesada, E; San-Félix, A; Sheen, CW; Sluis-Cremer, N, 2008)
"To evaluate whether an inter-individual variability in the activity of thymidine kinase (TK) and deoxycytidine kinase (dCK), which are involved in the first step of phosphorylation of some nucleoside analogues, exists in antiretroviral-naive, HIV-seropositive patients."	3.73	Thymidine kinase and deoxycytidine kinase activity in mononuclear cells from antiretroviral-naive HIV-infected patients. ( Antonelli, G; Antonelli, L; Butera, O; Gianotti, N; Girardi, E; Iaiani, G; Lazzarin, A; Mazzi, R; Parisi, SG; Turriziani, O, 2005)
"Oxygen-sulfur exchange at the C-4 carbonyl of several modified pyrimidine nucleosides, including 3'-azido-3'-deoxythymidine (AZT), is described in an effort to enhance the lipophilicity and, thereby, the delivery to the central nervous system of the sulfur analogues without compromising the anti-HIV activities of the parental structures."	3.68	Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders. ( Horwitz, JP; Kessel, D; Meltsner, BR; Palomino, E, 1990)
" Neither 3'-isocyano-3'-deoxythymidine (11) nor 3'-isocyano-2',3'-dideoxyuridine (12) showed anti-HIV activity at noncytotoxic concentrations."	3.68	Synthesis, antiretrovirus effects, and phosphorylation kinetics of 3'-isocyano-3'-deoxythymidine and 3'-isocyano-2',3'-dideoxyuridine. ( Balzarini, J; De Clercq, E; Hiebl, J; Zbiral, E, 1990)
"The thymidine analog 3'-azido-3'-deoxythymidine (BW A509U, azidothymidine) can inhibit human immunodeficiency virus (HIV) replication effectively in the 50-500 nM range [Mitsuya, H."	3.67	Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. ( Bolognesi, DP; Broder, S; Freeman, GA; Furman, PA; Fyfe, JA; Lehrman, SN; Mitsuya, H; Rideout, JL; St Clair, MH; Weinhold, K, 1986)
"The ability of granulocyte-macrophage colony-stimulating factor (GM-CSF) and 3'-azido-3'-deoxythymidine (AZT) to inhibit human immunodeficiency virus (HIV) in the U-937 monocytic cell line was examined."	3.67	Synergistic activity of granulocyte-macrophage colony-stimulating factor and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro. ( Gillis, JM; Hammer, SM, 1987)
"The novel 5-chloro-, 5-bromo-, and 5-iodo-derivatives of 3'-fluoro-2',3'-dideoxyuridine (FddUrd), designated FddCIUrd, FddBrUrd, and FddIUrd, respectively, have been synthesized and evaluated for their antiretrovirus activity against human immunodeficiency virus (HIV) and murine Moloney sarcoma virus."	3.67	5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine. ( Baba, M; Balzarini, J; De Clercq, E; Herdewijn, P; Pauwels, R; Schols, D; Van Aerschot, A, 1989)
"The effect of D-penicillamine on the replication of the Human Immunodeficiency Virus (HIV) in H9 T-lymphoblastoid cells was evaluated."	3.67	Effect of D-penicillamine on the expression and propagation of the human immunodeficiency virus by H9 T-lymphoblastoid cells. ( Bitterlich, G; Dierich, MP; Hengster, P; Hofbauer, J; Larcher, C; Myones, BL; Schulz, TF; Sölder, B; Wachter, H, 1989)
"The 3'-fluoro-and 3'-azido-substituted derivatives of 2',3'-dideoxythymidine (ddThd), 2',3'-dideoxyuridine (ddUrd), 2',3'-dideoxy-5-ethyluridine (ddEtUrd) and 2',3'-dideoxycytidine (ddCyd) have been synthesized and evaluated for their anti-retrovirus activity [against human immunodeficiency virus (HIV) and murine Moloney sarcoma virus (MSV)]."	3.67	Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues. ( Baba, M; Balzarini, J; De Clerq, E; Herdewijn, P; Pauwels, R, 1988)
"'Ampligen', a non-toxic, mismatched polymer of double-stranded RNA with antiviral and immunomodulatory activities reduced the concentration of zidovudine (azidothymidine, AZT; 'Retrovir', Wellcome) required for inhibitory activity against human immunodeficiency virus (HIV) in vitro."	3.67	Mismatched double-stranded RNA (ampligen) reduces concentration of zidovudine (azidothymidine) required for in-vitro inhibition of human immunodeficiency virus. ( Carter, WA; Mitchell, WM; Montefiori, DC; Robinson, WE; Strayer, DR, 1987)
"Five dose regimens of 2',3'-dideoxycytidine (ddC) were administered, intravenously for 2 weeks then orally for 4 or more weeks, to 20 patients with acquired immunodeficiency syndrome (AIDS) or AIDS-related complex (ARC)."	3.67	Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT). ( Allain, JP; Dubinsky, R; Fischl, MA; Klecker, RW; McAtee, N; McNeely, MC; Perno, CF; Thomas, RV; Wills, RJ; Yarchoan, R, 1988)
"In a study of treatment by zidovudine in 106 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex, an acute meningo-encephalitic illness developed in 4 of 21 patients within 17 days after the dose of zidovudine had had to be reduced because of myelotoxicity."	3.67	Acute meningo-encephalitis on dose reduction of zidovudine. ( Forster, S; Helbert, M; Jeffries, D; Kocsis, A; Peddle, B; Pinching, AJ; Robinson, D, 1988)
"2',3'-Dideoxythymidine (ddThd) and its 2',3'-unsaturated derivative 2',3'-dideoxythymidinene (ddeThd) are potent and selective inhibitors of human immunodeficiency virus (HIV) in vitro."	3.67	Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro. ( Baba, M; De Clercq, E; Desmyter, J; Herdewijn, P; Pauwels, R; Vandeputte, M, 1987)
"The effect of 3'-azido-2',3'-dideoxythymidine (AZT) on the human immunodeficiency virus (HIV)-associated giant cell formation was studied in vitro."	3.67	Effect of 3'-azido-2',3'-dideoxythymidine (AZT) and neutralizing antibody on human immunodeficiency virus (HIV)-induced cytopathic effects: implication of giant cell formation for the spread of virus in vivo. ( Kobayashi, N; Matsuda, A; Nakashima, H; Tochikura, T; Ueda, T; Yamamoto, N, 1987)
"The effect of 3'-azido-3'-deoxythymidine (AZT) on replication of human immunodeficiency virus (HIV) in various hematopoietic cell lines was investigated."	3.67	Suppression of human immunodeficiency virus replication by 3'-azido-3'-deoxythymidine in various human hematopoietic cell lines in vitro: augmentation of the effect by lentinan. ( Kaneko, Y; Kobayashi, N; Nakashima, H; Tochikura, TS; Yamamoto, N, 1987)
"Six HIV-antigenaemic patients with AIDS or AIDS-related complex were studied to assess the effect of treatment with low-dose zidovudine (250 mg) in 6-hourly doses on HIV antigen (HIV-Ag) levels in cerebrospinal fluid (CSF)."	3.67	Decline of HIV antigen levels in cerebrospinal fluid during treatment with low-dose zidovudine. ( Cload, P; Danner, SA; de Gans, J; de Wolf, F; Derix, MM; Eeftinck Schattenkerk, JK; Goudsmit, J; Lange, JM; Ongerboer de Visser, BW, 1988)
"Among 16 patients with the acquired immunodeficiency syndrome (AIDS) or AIDS-related complex studied serially, 12 had or developed antigenemia ranging from 16 to 3006 pg/mL in plasma."	2.66	Human immunodeficiency virus (HIV) antigenemia (p24) in the acquired immunodeficiency syndrome (AIDS) and the effect of treatment with zidovudine (AZT). ( Despotes, JC; Emeson, EE; Falk, LA; Jackson, GG; Knigge, M; Mack, D; Paul, DA; Rubenis, M, 1988)
"In patients not requiring HAART, treatment of hepatitis B should preferably consist of drugs without activity against HIV, such as pegylated interferon or adefovir."	2.44	[Hepatitis B in patients with HIV infection]. ( Barreiro, P; García-Samaniego, J; Martín-Carbonero, L, 2008)
"Patients with the acquired immunodeficiency syndrome (AIDS) die of overwhelming infections as a consequence of the destruction of the T4 subset of lymphocytes."	2.37	Developmental therapeutics and the acquired immunodeficiency syndrome. ( Broder, S; Chabner, BA; DeVita, VT; Fauci, AS; Kovacs, JA, 1987)
" At concentrations of up to 50 microM no natural 2'-deoxynucleosides, including thymidine, were able to reverse the toxic effects of AZT."	1.27	Uridine reverses the toxicity of 3'-azido-3'-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity. ( Carlisle, R; Schinazi, RF; Sommadossi, JP; Zhou, Z, 1988)

Research

Studies (92)

Timeframe	Studies, this research(%)	All Research%
pre-1990	71 (77.17)	18.7374
1990's	9 (9.78)	18.2507
2000's	10 (10.87)	29.6817
2010's	2 (2.17)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Palomino, E	1
Meltsner, BR	1
Kessel, D	1
Horwitz, JP	1
Herdewijn, P	8
Balzarini, J	11
De Clercq, E	10
Pauwels, R	7
Baba, M	6
Broder, S	12
Vanderhaeghe, H	2
Sigaloff, KC	1
Kayiwa, J	1
Musiime, V	1
Calis, JC	1
Kaudha, E	1
Mukuye, A	1
Matama, C	1
Nankya, I	1
Nakatudde, L	1
Dekker, JT	1
Hamers, RL	1
Mugyenyi, P	1
Rinke De Wit, TF	1
Kityo, C	1
Barreiro, P	2
Martín-Carbonero, L	1
García-Samaniego, J	1
López Bernaldo de Quirós, JC	1
Gaynor, JW	1
Cosstick, R	1
de Mendoza, C	1
Paxinos, E	1
Camino, N	1
Núñez, M	1
Soriano, V	1
Calvo, KC	1
Wang, X	1
Koser, GF	1
Goldschmidt, V	1
Marquet, R	1
Ross, L	1
Parkin, N	1
Chappey, C	1
Fisher, R	1
Clair, MS	1
Bates, M	1
Tisdale, M	1
Lanier, ER	1
Turriziani, O	1
Butera, O	1
Gianotti, N	1
Parisi, SG	1
Mazzi, R	1
Girardi, E	1
Iaiani, G	1
Antonelli, L	1
Lazzarin, A	1
Antonelli, G	1
Wirden, M	1
Malet, I	1
Derache, A	1
Marcelin, AG	1
Roquebert, B	1
Simon, A	1
Kirstetter, M	1
Joubert, LM	1
Katlama, C	1
Calvez, V	1
Park, AY	1
Moon, HR	1
Kim, KR	1
Chun, MW	1
Jeong, LS	1
Bonache, MC	1
Quesada, E	1
Sheen, CW	1
Sluis-Cremer, N	1
Pérez-Pérez, MJ	1
Camarasa, MJ	1
San-Félix, A	1
Xu, ZQ	1
Qiu, YL	1
Chokekijchai, S	1
Mitsuya, H	5
Zemlicka, J	1
Bochkarev, AV	1
Zavgorodniĭ, SG	1
Zhdanov, AS	1
Gurskaia, GV	1
Chen, MS	2
Suttmann, RT	1
Wu, JC	1
Prisbe, EJ	1
Almer, H	1
Classon, B	1
Samuelsson, B	1
Kvarnström, I	1
Yuzhakov, AA	1
Chidgeavadze, ZG	1
Beabealash-villi, RS	1
Hiebl, J	1
Zbiral, E	1
Wigerinck, P	1
Van Aerschot, A	2
Janssen, G	1
Claes, P	1
Camerman, N	1
Mastropaolo, D	1
Camerman, A	1
Furman, PA	3
Fyfe, JA	3
St Clair, MH	1
Weinhold, K	1
Rideout, JL	2
Freeman, GA	2
Lehrman, SN	1
Bolognesi, DP	1
Vogt, M	1
Schooley, RT	4
Hirsch, MS	6
Nakashima, H	6
Matsui, T	2
Harada, S	2
Kobayashi, N	3
Matsuda, A	3
Ueda, T	3
Yamamoto, N	8
Vogt, MW	3
Hartshorn, KL	2
Chou, TC	3
Coleman, LA	2
Crumpacker, C	1
DeVita, VT	1
Fauci, AS	1
Kovacs, JA	1
Chabner, BA	1
Kaplan, JC	3
Ueno, R	3
Kuno, S	3
Herzyk, P	1
Beveridge, A	1
Neidle, S	1
Berenbaum, MC	1
Lin, TS	3
Schinazi, RF	3
Prusoff, WH	3
Hammer, SM	1
Gillis, JM	1
Smith, MS	1
Brian, EL	1
Pagano, JS	2
Looney, DJ	1
Wong-Staal, F	1
Webb, TR	1
Majumdar, C	1
Abbotts, J	1
Wilson, SH	1
Mansuri, MM	1
Starrett, JE	1
Ghazzouli, I	1
Hitchcock, MJ	1
Sterzycki, RZ	1
Brankovan, V	1
August, EM	1
Sommadossi, JP	2
Schols, D	1
Bitterlich, G	1
Larcher, C	1
Sölder, B	1
Hengster, P	1
Myones, BL	1
Hofbauer, J	1
Schulz, TF	1
Wachter, H	1
Dierich, MP	1
Desmyter, J	2
Goubau, P	1
Vandeputte, M	2
Richman, DD	2
Kornbluth, RS	1
Carson, DA	1
Cooney, DA	1
Dalal, M	1
Kang, GJ	1
Cupp, JE	1
DeClercq, E	1
Johns, DG	2
Lin, JC	1
Zhang, ZX	1
Smith, MC	1
Biron, K	1
De Clerq, E	1
Yarchoan, R	3
Durno, AG	1
Paradis, TJ	1
Agyei-Aye, K	1
Baker, DC	1
Mitchell, WM	1
Montefiori, DC	1
Robinson, WE	1
Strayer, DR	1
Carter, WA	1
Perno, CF	1
Thomas, RV	1
Klecker, RW	1
Allain, JP	2
Wills, RJ	1
McAtee, N	1
Fischl, MA	1
Dubinsky, R	1
McNeely, MC	1
de Wolf, F	2
Lange, JM	3
Goudsmit, J	3
Cload, P	2
de Gans, J	3
Schellekens, PT	1
Coutinho, RA	1
Fiddian, AP	1
van der Noordaa, J	1
Reiss, P	1
Boucher, CA	1
Danner, SA	2
Fleury, HJ	1
Morere, G	1
Delord, B	1
Faivre, R	1
Helbert, M	1
Robinson, D	1
Peddle, B	1
Forster, S	1
Kocsis, A	1
Jeffries, D	1
Pinching, AJ	1
Steel, M	1
Tiessens, G	1
Portegies, P	1
Weber, J	1
Cardin, AD	1
Bowlin, TL	1
Krstenansky, JL	1
Kinney-Thomas, E	1
Hamamoto, Y	1
Barry, DW	1
Tochikura, T	1
Tochikura, TS	1
Kaneko, Y	1
Ikuta, K	2
Imai, H	2
Ueda, S	2
Suehiro, S	2
Kato, S	2
Jackson, GG	1
Paul, DA	1
Falk, LA	1
Rubenis, M	1
Despotes, JC	1
Mack, D	1
Knigge, M	1
Emeson, EE	1
Derix, MM	1
Eeftinck Schattenkerk, JK	1
Ongerboer de Visser, BW	1
Lefrere, JJ	1
Courouce, AM	1
Salmon, C	1
Permin, H	1
Dickmeiss, E	1
Petersen, CS	1
Ersbøll, J	1
Mathiesen, L	1
Krebs, HJ	1
Glaser, V	1
Matthes, E	1
Lehmann, C	1
Scholz, D	1
Rosenthal, HA	1
Langen, P	1
Torrence, PF	1
Kinjo, J	1
Lesiak, K	1
Carlisle, R	1
Zhou, Z	1
Barnes, DM	1
Chaisson, RE	1
Leuther, M	1
Volberding, PA	1
Blumberg, RS	1
Byington, R	1
Ito, M	1
Shigeta, S	1
Jablon, L	1
Lyerly, HK	1
Cohen, OJ	1
Weinhold, KJ	1
Gallo, RC	1
Elwell, LP	1
Ferone, R	1
Hill, JA	1
Ray, PH	1
Richards, CA	1
Singer, SC	1
Knick, VB	1

Clinical Trials (2)

Trial Overview

Trial	Phase	Enrollment	Study Type	Start Date	Status
Uridine Supplementation, Mitochondrial Function, and Glucose Metabolism in HIV[NCT00471614]	Phase 2	3 participants (Actual)	Interventional	2007-04-30	Completed
A Randomized Pilot Study for the Treatment of AIDS or AIDS Related Complex With an Alternating or Simultaneous Combination Regimen of AZT and 2',3'-Dideoxyinosine[NCT00001267]	Phase 3	42 participants	Interventional	1990-10-31	Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for thymidine and HIV

Article	Year
[Hepatitis B in patients with HIV infection]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 7 Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Antiviral Agents; Comorbidity; Deox	2008
[Tenofovir DF in rescue regimens]. Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8 Topics: Adenine; Anti-HIV Agents; Antimetabolites; Clinical Trials, Phase III as Topic; Drug Resistance, Mul	2008
Primer unblocking by HIV-1 reverse transcriptase and resistance to nucleoside RT inhibitors (NRTIs). The international journal of biochemistry & cell biology, 2004, Volume: 36, Issue:9 Topics: Adenosine Triphosphate; DNA Primers; Drug Resistance, Multiple, Viral; Foscarnet; HIV; HIV Reverse T	2004
Developmental therapeutics and the acquired immunodeficiency syndrome. Annals of internal medicine, 1987, Volume: 106, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Deoxyribonucleosides; HIV; Humans; Interferons	1987
Progress in the development of antiviral therapy for HTLV-III-associated diseases. Important advances in oncology, 1987 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; HIV; Humans; Phosphonoace	1987
Spectrum of antiviral activity and mechanism of action of zidovudine. An overview. The American journal of medicine, 1988, Aug-29, Volume: 85, Issue:2A Topics: Animals; Antiviral Agents; HIV; Humans; Retroviridae; Thymidine; Virus Replication; Zidovudine	1988
Treatment of human immunodeficiency virus infections. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Drug Therapy, Combination; HIV; Humans; Ribavi	1987
Strategies for the future chemotherapy of human immunodeficiency virus (HIV). Haematology and blood transfusion, 1987, Volume: 31 Topics: Acquired Immunodeficiency Syndrome; Drug Evaluation; HIV; Humans; Thymidine; Zidovudine	1987
Development of antiretroviral therapy for the acquired immunodeficiency syndrome and related disorders. A progress report. The New England journal of medicine, 1987, Feb-26, Volume: 316, Issue:9 Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Structure-Activity Relationship; Thymidine; Zidovud	1987

Trials

4 trials available for thymidine and HIV

Article	Year
[Chemotherapy and immunoprophylaxis of HIV infection]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1986, Nov-25, Volume: 75, Issue:48 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Clinical Trials as Topic; Foscarnet; HIV; Huma	1986
Effect of zidovudine on serum human immunodeficiency virus antigen levels in symptom-free subjects. Lancet (London, England), 1988, Feb-20, Volume: 1, Issue:8582 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antigens, Viral; Antiviral Agents; Double-Blind Metho	1988
Human immunodeficiency virus (HIV) antigenemia (p24) in the acquired immunodeficiency syndrome (AIDS) and the effect of treatment with zidovudine (AZT). Annals of internal medicine, 1988, Volume: 108, Issue:2 Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Complex; Antigens, Viral; Antiviral Agents; Clinica	1988
"On the shelf" AIDS drug in clinical trial. Science (New York, N.Y.), 1987, Oct-16, Volume: 238, Issue:4825 Topics: Acquired Immunodeficiency Syndrome; Clinical Trials as Topic; Fusidic Acid; HIV; Humans; Thymidine;	1987

Other Studies

79 other studies available for thymidine and HIV

Article	Year
Synthesis and in vitro evaluation of some modified 4-thiopyrimidine nucleosides for prevention or reversal of AIDS-associated neurological disorders. Journal of medicinal chemistry, 1990, Volume: 33, Issue:1 Topics: AIDS Dementia Complex; Animals; Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Chemistr	1990
3'-substituted 2',3'-dideoxynucleoside analogues as potential anti-HIV (HTLV-III/LAV) agents. Journal of medicinal chemistry, 1987, Volume: 30, Issue:8 Topics: Antiviral Agents; Cell Line; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral; Deoxyribon	1987
Short communication: high rates of thymidine analogue mutations and dual-class resistance among HIV-infected Ugandan children failing first-line antiretroviral therapy. AIDS research and human retroviruses, 2013, Volume: 29, Issue:6 Topics: Amino Acid Substitution; Anti-HIV Agents; Child; Child, Preschool; Cross-Sectional Studies; Drug Res	2013
Dinucleotides containing 3'-S-phosphorothiolate linkages. Methods in molecular biology (Clifton, N.J.), 2011, Volume: 764 Topics: Antiviral Agents; Chemistry, Pharmaceutical; Dinucleoside Phosphates; Endonucleases; Hepatitis B; He	2011
Different viral rebound following discontinuation of antiretroviral therapy in cases of infection with viruses carrying L74V or thymidine-associated mutations. Journal of clinical microbiology, 2004, Volume: 42, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Amino Acid Substitution; Anti-HIV Agents; CD4 Lymphocyte Count;	2004
Bis-ketol nucleoside triesters as prodrugs of the antiviral nucleoside triphosphate analogues of 3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:3 Topics: Anti-HIV Agents; Cell Line; Esters; HIV; Humans; Molecular Structure; Nucleosides; Prodrugs; Stavudi	2004
Phenotypic impact of HIV reverse transcriptase M184I/V mutations in combination with single thymidine analog mutations on nucleoside reverse transcriptase inhibitor resistance. AIDS (London, England), 2004, Aug-20, Volume: 18, Issue:12 Topics: Adenine; Algorithms; Anti-HIV Agents; Databases, Genetic; Didanosine; Dideoxynucleosides; Drug Resis	2004
Thymidine kinase and deoxycytidine kinase activity in mononuclear cells from antiretroviral-naive HIV-infected patients. AIDS (London, England), 2005, Mar-25, Volume: 19, Issue:5 Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Deoxycytidine Kinase; Fema	2005
Clonal analyses of HIV quasispecies in patients harbouring plasma genotype with K65R mutation associated with thymidine analogue mutations or L74V substitution. AIDS (London, England), 2005, Mar-24, Volume: 19, Issue:6 Topics: Amino Acid Substitution; Clone Cells; Genotype; HIV; HIV Infections; Humans; Mutation; Thymidine	2005
Synthesis of novel L-N-MCd4T as a potent anti-HIV agent. Organic & biomolecular chemistry, 2006, Nov-21, Volume: 4, Issue:22 Topics: Anti-HIV Agents; Bridged Bicyclo Compounds; HIV; Humans; Lymphocytes; Microbial Sensitivity Tests; M	2006
Novel N-3 substituted TSAO-T derivatives: synthesis and anti-HIV-evaluation. Nucleosides, nucleotides & nucleic acids, 2008, Volume: 27, Issue:4 Topics: Azides; Benzophenones; Cell Line; Drug Design; HIV; HIV Reverse Transcriptase; HIV-1; HIV-2; Protein	2008
Unsaturated acyclic analogues of 2'-deoxyadenosine and thymidine containing fluorine: synthesis and biological activity. Journal of medicinal chemistry, 1995, Mar-17, Volume: 38, Issue:6 Topics: Adenine; Animals; Antineoplastic Agents; Antiviral Agents; Cattle; Deoxyadenosines; HIV; Humans; Hyd	1995
[X-ray structural study of 3'-O-methylthiomethylthymidine and 3'-O-methylsulfinylmethylthymidine--potential inhibitors of HIV]. Bioorganicheskaia khimiia, 1995, Volume: 21, Issue:3 Topics: Antiviral Agents; HIV; Nucleic Acid Conformation; Thymidine; X-Ray Diffraction	1995
Metabolism of 4'-azidothymidine. A compound with potent and selective activity against the human immunodeficiency virus. The Journal of biological chemistry, 1992, Jan-05, Volume: 267, Issue:1 Topics: Cell Line; DNA; HIV; Humans; Kinetics; Phosphorylation; Substrate Specificity; T-Lymphocytes; Thymid	1992
Synthesis of a phosphonomethyl analogue of 3'-deoxy-3-fluorothymidine. Acta chemica Scandinavica (Copenhagen, Denmark : 1989), 1991, Volume: 45, Issue:7 Topics: Antiviral Agents; Cells, Cultured; HIV; Humans; Thymidine	1991
A new method of synthesis of 3'-mercapto-3'-deoxythymidine. Nucleic acids symposium series, 1991, Issue:24 Topics: Antiviral Agents; Cell Line; HIV; Humans; T-Lymphocytes; Thymidine; Zidovudine	1991
Synthesis, antiretrovirus effects, and phosphorylation kinetics of 3'-isocyano-3'-deoxythymidine and 3'-isocyano-2',3'-dideoxyuridine. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: Antimetabolites; Antiviral Agents; Cell Survival; Chemical Phenomena; Chemistry; Dideoxynucleosides;	1990
Synthesis and antiviral activity of 3'-heterocyclic substituted 3'-deoxythymidines. Journal of medicinal chemistry, 1990, Volume: 33, Issue:2 Topics: Animals; Antiviral Agents; Cell Transformation, Viral; Cells, Cultured; Chemical Phenomena; Chemistr	1990
Structure of the anti-human immunodeficiency virus agent 3'-fluoro-3'-deoxythymidine and electronic charge calculations for 3'-deoxythymidines. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:9 Topics: Antiviral Agents; Dideoxynucleosides; HIV; Hydrogen Bonding; Molecular Conformation; Molecular Struc	1990
Phosphorylation of 3'-azido-3'-deoxythymidine and selective interaction of the 5'-triphosphate with human immunodeficiency virus reverse transcriptase. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:21 Topics: Antiviral Agents; Cell Survival; HIV; Humans; Kinetics; Nucleic Acid Synthesis Inhibitors; Phosphory	1986
Inhibition of replication and cytopathic effect of human T cell lymphotropic virus type III/lymphadenopathy-associated virus by 3'-azido-3'-deoxythymidine in vitro. Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:6 Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; HIV; HIV Antigens; Human	1986
Ribavirin antagonizes the effect of azidothymidine on HIV replication. Science (New York, N.Y.), 1987, Mar-13, Volume: 235, Issue:4794 Topics: Cell Line; HIV; Humans; Lymphocytes; Monocytes; Phosphorylation; Phytohemagglutinins; Ribavirin; Rib	1987
Antiviral therapy. Scientific American, 1987, Volume: 256, Issue:4 Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Antiviral Agents; Cytomegalovirus; DNA, Viral; Drug R	1987
Dextran sulphate, a potent anti-HIV agent in vitro having synergism with zidovudine. Lancet (London, England), 1987, Jun-13, Volume: 1, Issue:8546 Topics: Antiviral Agents; Dextran Sulfate; Dextrans; Drug Synergism; HIV; Humans; Thymidine; Zidovudine	1987
Conformational properties of 3'-azido-3'deoxy-thymidine (AZT), an inhibitor of HIV reverse transcriptase. Biochemical and biophysical research communications, 1987, Jun-30, Volume: 145, Issue:3 Topics: Antiviral Agents; HIV; Models, Molecular; Molecular Conformation; Reverse Transcriptase Inhibitors;	1987
Anti-HIV synergy between dextran sulphate and zidovudine. Lancet (London, England), 1987, Aug-22, Volume: 2, Issue:8556 Topics: Dextran Sulfate; Dextrans; Drug Synergism; HIV; Thymidine; Zidovudine	1987
Potent and selective in vitro activity of 3'-deoxythymidin-2'-ene (3'-deoxy-2',3'-didehydrothymidine) against human immunodeficiency virus. Biochemical pharmacology, 1987, Sep-01, Volume: 36, Issue:17 Topics: Antiviral Agents; Deoxycytidine; HIV; Humans; Monocytes; Retroviridae Proteins; RNA-Directed DNA Pol	1987
Anti-HIV synergism between dextran sulphate and zidovudine. Lancet (London, England), 1987, Oct-03, Volume: 2, Issue:8562 Topics: Antiviral Agents; Dextran Sulfate; Dextrans; Drug Synergism; HIV; Humans; Thymidine; Zidovudine	1987
Synergistic activity of granulocyte-macrophage colony-stimulating factor and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:7 Topics: Antiviral Agents; Cell Line; Drug Synergism; Fluorescent Antibody Technique; HIV; Humans; Interleuki	1987
Resumption of virus production after human immunodeficiency virus infection of T lymphocytes in the presence of azidothymidine. Journal of virology, 1987, Volume: 61, Issue:12 Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; DNA, Viral; Drug Resistance, Microbial; H	1987
Dextran sulfate suppression of viruses in the HIV family: inhibition of virion binding to CD4+ cells. Science (New York, N.Y.), 1988, Apr-29, Volume: 240, Issue:4852 Topics: Antigens, Differentiation, T-Lymphocyte; Cell Line; Dextran Sulfate; Dextrans; Dideoxynucleosides; D	1988
1-(2,3-Anhydro-beta-D-lyxofuranosyl)cytosine derivatives as potential inhibitors of the human immunodeficiency virus. Journal of medicinal chemistry, 1988, Volume: 31, Issue:7 Topics: Ancitabine; Chemical Phenomena; Chemistry; Cytarabine; Cytidine; HIV; Magnetic Resonance Spectroscop	1988
Studies on the mechanism of human immunodeficiency virus reverse transcriptase. Steady-state kinetics, processivity, and polynucleotide inhibition. The Journal of biological chemistry, 1988, Oct-25, Volume: 263, Issue:30 Topics: Algorithms; DNA Replication; DNA-Directed DNA Polymerase; HIV; Kinetics; Poly C; Poly T; Polynucleot	1988
1-(2,3-Dideoxy-beta-D-glycero-pent-2-enofuranosyl)thymine. A highly potent and selective anti-HIV agent. Journal of medicinal chemistry, 1989, Volume: 32, Issue:2 Topics: Antiviral Agents; Bone Marrow; Dideoxynucleosides; HIV; Stavudine; Thymidine; Zidovudine	1989
Differential patterns of intracellular metabolism of 2',3'-didehydro-2',3'-dideoxythymidine and 3'-azido-2',3'-dideoxythymidine, two potent anti-human immunodeficiency virus compounds. The Journal of biological chemistry, 1989, Apr-15, Volume: 264, Issue:11 Topics: Animals; Antiviral Agents; Cell Line; Cell Survival; Deoxycytidine; Deoxyribonucleotides; Dideoxynuc	1989
5-Halogeno-3'-fluoro-2',3'-dideoxyuridines as inhibitors of human immunodeficiency virus (HIV): potent and selective anti-HIV activity of 3'-fluoro-2',3'-dideoxy-5-chlorouridine. Molecular pharmacology, 1989, Volume: 35, Issue:5 Topics: Antiviral Agents; Cell Transformation, Viral; Deoxycytidine; Dideoxynucleosides; Halogens; HIV; Phos	1989
Effect of D-penicillamine on the expression and propagation of the human immunodeficiency virus by H9 T-lymphoblastoid cells. Arzneimittel-Forschung, 1989, Volume: 39, Issue:8 Topics: Cells, Cultured; HIV; HIV Antigens; Humans; Penicillamine; Spectrometry, Fluorescence; T-Lymphocytes	1989
Sensitive and rapid assay on MT-4 cells for detection of antiviral compounds against the AIDS virus. Journal of virological methods, 1987, Volume: 16, Issue:3 Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Deoxycyti	1987
Failure of dideoxynucleosides to inhibit human immunodeficiency virus replication in cultured human macrophages. The Journal of experimental medicine, 1987, Oct-01, Volume: 166, Issue:4 Topics: Adenosine Kinase; Cell Line; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Dideoxyadenosine;	1987
2',3'-Dideoxycytidine: regulation of its metabolism and anti-retroviral potency by natural pyrimidine nucleosides and by inhibitors of pyrimidine nucleotide synthesis. Molecular pharmacology, 1987, Volume: 32, Issue:6 Topics: Animals; Antiviral Agents; Deoxycytidine; Deoxycytosine Nucleotides; HIV; Humans; Leukemia L1210; Mi	1987
The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species. Biochemical pharmacology, 1988, Mar-01, Volume: 37, Issue:5 Topics: Animals; Antiviral Agents; Cell Line; Deoxycytidine; HIV; Humans; Mice; Mice, Inbred C3H; Moloney mu	1988
Anti-human immunodeficiency virus agent 3'-azido-3'-deoxythymidine inhibits replication of Epstein-Barr virus. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:2 Topics: Cell Line; Cytomegalovirus; Herpesvirus 3, Human; Herpesvirus 4, Human; HIV; Simplexvirus; Thymidine	1988
Inhibition of infectivity and replication of HIV-2 and SIV in helper T-cells by 2',3'-dideoxynucleosides in vitro. AIDS research and human retroviruses, 1988, Volume: 4, Issue:2 Topics: Cytopathogenic Effect, Viral; Deoxyadenosines; Deoxycytidine; Dideoxyadenosine; HIV; In Vitro Techni	1988
Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues. Biochemical pharmacology, 1988, Jul-15, Volume: 37, Issue:14 Topics: Animals; Antimetabolites; Antiviral Agents; Cell Division; Deoxycytidine; Deoxycytidine Kinase; Dide	1988
Synergistic interaction of 2',3'-dideoxycytidine and recombinant interferon-alpha-A on replication of human immunodeficiency virus type 1. The Journal of infectious diseases, 1988, Volume: 158, Issue:2 Topics: Antiviral Agents; Cell Line; Deoxycytidine; Drug Synergism; HIV; Humans; Interferon Type I; Leukocyt	1988
Synthesis and evaluation of a series of 1-(3-alkyl-2,3-dideoxy-alpha,beta-D-erythro-pentofuranosyl)thymines. Carbohydrate research, 1988, Dec-01, Volume: 183, Issue:2 Topics: Acetylation; Chemical Phenomena; Chemistry; Chemistry, Physical; Chromatography, High Pressure Liqui	1988
Mismatched double-stranded RNA (ampligen) reduces concentration of zidovudine (azidothymidine) required for in-vitro inhibition of human immunodeficiency virus. Lancet (London, England), 1987, Apr-18, Volume: 1, Issue:8538 Topics: Antiviral Agents; Cell Line; HIV; Humans; Poly I-C; Poly U; Polyribonucleotides; Thymidine; Virus Re	1987
Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT). Lancet (London, England), 1988, Jan-16, Volume: 1, Issue:8577 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Deoxycytidine; Drug Administration	1988
Resumption of HIV antigen production during continuous zidovudine treatment. Lancet (London, England), 1988, Feb-20, Volume: 1, Issue:8582 Topics: Acquired Immunodeficiency Syndrome; Antigens, Viral; Antiviral Agents; HIV; Humans; Thymidine; Zidov	1988
Isolation of HIV from mononuclear cells of patients receiving zidovudine. Lancet (London, England), 1988, Apr-16, Volume: 1, Issue:8590 Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Complex; Antiviral Agents; HIV; Humans; Leuk	1988
Acute meningo-encephalitis on dose reduction of zidovudine. Lancet (London, England), 1988, Jun-04, Volume: 1, Issue:8597 Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Adult; AIDS-Related Complex; Antiviral Agents; Fo	1988
IVth international AIDS conference. Lancet (London, England), 1988, Jul-02, Volume: 2, Issue:8601 Topics: Acquired Immunodeficiency Syndrome; Adult; Antibodies, Viral; Child; Congresses as Topic; Female; He	1988
Acute meningoencephalitis on dose reduction of zidovudine. Lancet (London, England), 1988, Sep-03, Volume: 2, Issue:8610 Topics: Acquired Immunodeficiency Syndrome; Acute Disease; HIV; Humans; Meningoencephalitis; Thymidine; Viru	1988
AIDS: the virus, antivirals and vaccines. British journal of hospital medicine, 1987, Volume: 37, Issue:2 Topics: Acquired Immunodeficiency Syndrome; Antimony; Antiviral Agents; Foscarnet; Genes, Viral; HIV; Humans	1987
Inhibition of lymphocyte proliferation by synthetic peptides homologous to human plasma apolipoproteins B and E. Biochemical and biophysical research communications, 1988, Jul-29, Volume: 154, Issue:2 Topics: Apolipoproteins B; Apolipoproteins E; Binding Sites; Cell Division; Heparin; HIV; Humans; Lymphocyte	1988
Both 2',3'-dideoxythymidine and its 2',3'-unsaturated derivative (2',3'-dideoxythymidinene) are potent and selective inhibitors of human immunodeficiency virus replication in vitro. Biochemical and biophysical research communications, 1987, Jan-15, Volume: 142, Issue:1 Topics: Antigens, Viral; Antiviral Agents; Cell Line; Cell Survival; Cytopathogenic Effect, Viral; Dideoxynu	1987
Antiviral activity of 2',3'-dideoxycytidin-2'-ene (2',3'-dideoxy-2',3'-didehydrocytidine) against human immunodeficiency virus in vitro. Biochemical pharmacology, 1987, Feb-01, Volume: 36, Issue:3 Topics: Antiviral Agents; Deoxycytidine; Fluorescence; HIV; Humans; In Vitro Techniques; Monocytes; Thymidin	1987
Substances affecting the infection and replication of human immunodeficiency virus (HIV). AIDS research, 1986, Volume: 2 Suppl 1 Topics: Cell Line; Cytopathogenic Effect, Viral; Deltaretrovirus; Dinoprostone; HIV; Humans; Interferon-gamm	1986
Inhibitory effect of 2',3'-didehydro-2',3'-dideoxynucleosides on infectivity, cytopathic effects, and replication of human immunodeficiency virus. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:6 Topics: Antigens, Viral; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Dideoxynucleosides	1987
Effect of 3'-azido-2',3'-dideoxythymidine (AZT) and neutralizing antibody on human immunodeficiency virus (HIV)-induced cytopathic effects: implication of giant cell formation for the spread of virus in vivo. Virology, 1987, Volume: 159, Issue:1 Topics: Antibodies, Viral; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Antiviral Agents; Cel	1987
Suppression of human immunodeficiency virus replication by 3'-azido-3'-deoxythymidine in various human hematopoietic cell lines in vitro: augmentation of the effect by lentinan. Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:6 Topics: Cell Line; Drug Synergism; Hematopoietic Stem Cells; HIV; Humans; Lentinan; Polysaccharides; T-Lymph	1987
Amplification of human immuno-deficiency virus production from a virus-producing cell line in culture at high cell density. Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:7 Topics: Cell Line; Culture Media; Electrophoresis, Polyacrylamide Gel; HIV; Humans; Membrane Proteins; Thymi	1987
Suppression by neurotropin of production of human immuno-deficiency virus by the virus-producing MOLT-4 cell line. Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:7 Topics: Acquired Immunodeficiency Syndrome; Antigens, Surface; Antigens, Viral; Cell Line; HIV; Humans; Poly	1987
Decline of HIV antigen levels in cerebrospinal fluid during treatment with low-dose zidovudine. AIDS (London, England), 1988, Volume: 2, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Antigens, Viral; Central Nervous System Diseases; HIV; HIV Antig	1988
HIV antigenemia and zidovudine. AIDS (London, England), 1988, Volume: 2, Issue:3 Topics: Antigens, Viral; Antiviral Agents; HIV; HIV Antigens; Humans; Thymidine; Zidovudine	1988
[HIV infection and AIDS. Paris, 25-29 January 1988]. Ugeskrift for laeger, 1988, Apr-18, Volume: 150, Issue:16 Topics: Acquired Immunodeficiency Syndrome; Antibody Formation; HIV; Humans; Thymidine; Zidovudine	1988
[Zidovudin (Retrovir). A new antiviral agents against human immunodeficiency viruses (HIV)]. Ugeskrift for laeger, 1988, Jan-25, Volume: 150, Issue:4 Topics: Antiviral Agents; Chemical Phenomena; Chemistry; HIV; Thymidine; Zidovudine	1988
The effect of zidovudine on antigen levels in HIV infection. New York state journal of medicine, 1988, Volume: 88, Issue:5 Topics: Acyclovir; Antigens, Viral; Antiviral Agents; Drug Therapy, Combination; HIV; HIV Antigens; HIV Sero	1988
Phosphorylation, anti-HIV activity and cytotoxicity of 3'-fluorothymidine. Biochemical and biophysical research communications, 1988, Jun-16, Volume: 153, Issue:2 Topics: Animals; Antiviral Agents; Cell Division; Cell Line; Cell Survival; Cytidine Diphosphate; Cytopathog	1988
AIDS dementia: synthesis and properties of a derivative of 3'-azido-3'-deoxythymidine (AZT) that may become 'locked' in the central nervous system. FEBS letters, 1988, Jul-04, Volume: 234, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Animals; Brain; Cell Line; Chemical Phenomena; Chemistry; Dement	1988
Uridine reverses the toxicity of 3'-azido-3'-deoxythymidine in normal human granulocyte-macrophage progenitor cells in vitro without impairment of antiretroviral activity. Antimicrobial agents and chemotherapy, 1988, Volume: 32, Issue:7 Topics: Antiviral Agents; Cytidine; HIV; Humans; In Vitro Techniques; Macrophages; Stem Cells; Thymidine; Ur	1988
Significant changes in HIV antigen level in the serum of patients treated with azidothymidine. The New England journal of medicine, 1986, Dec-18, Volume: 315, Issue:25 Topics: Acquired Immunodeficiency Syndrome; Antigens, Viral; Antiviral Agents; HIV; HIV Antigens; Humans; Th	1986
Synergistic inhibition of human immunodeficiency virus in vitro by azidothymidine and recombinant alpha A interferon. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:2 Topics: Antiviral Agents; Drug Synergism; HIV; Humans; Interferon Type I; Recombinant Proteins; Thymidine; V	1987
Inhibitory effect of glycyrrhizin on the in vitro infectivity and cytopathic activity of the human immunodeficiency virus [HIV (HTLV-III/LAV)]. Antiviral research, 1987, Volume: 7, Issue:3 Topics: Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Drug Interactions; Glycyrrhetinic Acid; G	1987
Azidothymidine (AZT). Connecticut medicine, 1987, Volume: 51, Issue:7 Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; HIV; Humans; Thymidine; Zidovudine	1987
Transmission of HIV by antigen presenting cells during T-cell activation: prevention by 3'-azido-3'-deoxythymidine. AIDS research and human retroviruses, 1987,Spring, Volume: 3, Issue:1 Topics: Antigen-Presenting Cells; Antiviral Agents; Cell Line; Cell Survival; HIV; Humans; Lymphocyte Activa	1987
Dideoxynucleosides are less inhibitory in vitro against human immunodeficiency virus type 2 (HIV-2) than against HIV-1. Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:12 Topics: Antiviral Agents; Cell Line; Drug Resistance, Microbial; HIV; Humans; T-Lymphocytes; Thymidine; Viru	1987
The AIDS virus. Scientific American, 1987, Volume: 256, Issue:1 Topics: Acquired Immunodeficiency Syndrome; Animals; Chlorocebus aethiops; Genes, Viral; History, 20th Centu	1987
Antibacterial activity and mechanism of action of 3'-azido-3'-deoxythymidine (BW A509U). Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:2 Topics: Antiviral Agents; DNA Replication; DNA, Bacterial; Drug Resistance, Microbial; Enterobacteriaceae; E	1987

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