thymidine has been researched along with Graves Disease in 27 studies
Graves Disease: A common form of hyperthyroidism with a diffuse hyperplastic GOITER. It is an autoimmune disorder that produces antibodies against the THYROID STIMULATING HORMONE RECEPTOR. These autoantibodies activate the TSH receptor, thereby stimulating the THYROID GLAND and hypersecretion of THYROID HORMONES. These autoantibodies can also affect the eyes (GRAVES OPHTHALMOPATHY) and the skin (Graves dermopathy).
| Excerpt | Relevance | Reference |
|---|---|---|
| "IgG associated with Graves' disease bind to the TSH receptor and alter thyroid growth and function, mainly through the stimulation of adenylyl cyclase." | 1.30 | Cyclooxygenase-dependent thyroid cell proliferation induced by immunoglobulins from patients with Graves' disease. ( Corda, D; De Filippis, V; Di Cerbo, A; Di Paola, R; Menzaghi, C, 1997) |
| "[3H]-thymidine uptake was suppressed to 56." | 1.29 | Effect of monensin on DNA synthesis in cultured human thyroid cells. ( Itoh, M; Okugawa, T, 1993) |
| "[3H]Thymidine incorporation was also significantly increased (p < 0." | 1.29 | Analysis of fibroblast-stimulating activity in IgG from patients with Graves' dermopathy. ( Davies, R; Metcalfe, RA; Weetman, AP, 1993) |
| "[3H]-thymidine uptake was more suppressed by IgG from patients with a smaller-sized goiter than by those with a larger-sized one." | 1.28 | Suppression of thyroid cell growth by serum IgG in Graves' disease. ( Itoh, M; Okugawa, T; Shimomura, N, 1992) |
| "This paper addresses the question: in Graves' disease is there a thyroid-growth stimulating IgG (TGI) separate from thyroid-stimulating antibody (TSAb)? Using the functioning rat thyroid line (FRTL5) cells for TGI (incorporation of [3H]-thymidine into DNA) and TSAb (increase in cAMP concentration) assays, we tested IgG from 30 Graves' patients." | 1.27 | Evidence supporting the identity in Graves' disease of thyroid-stimulating antibody and thyroid growth-promoting immunoglobulin G as assayed in FRTL5 cells. ( Jin, S; McKenzie, JM; Zakarija, M, 1988) |
| "[3H]thymidine incorporation was significantly inhibited in the presence of sera from patients with Graves' disease and chronic thyroiditis (P less than 0." | 1.27 | Antibody-dependent cell-mediated growth inhibition of rat thyroid cells, FRTL-5, in patients with autoimmune thyroid diseases. ( Arai, K; Iida, Y; Kasagi, K; Konishi, J; Misaki, T; Tokuda, Y, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (59.26) | 18.7374 |
| 1990's | 11 (40.74) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valente, WA | 1 |
| Vitti, P | 1 |
| Rotella, CM | 1 |
| Vaughan, MM | 1 |
| Aloj, SM | 1 |
| Grollman, EF | 1 |
| Ambesi-Impiombato, FS | 1 |
| Kohn, LD | 1 |
| Balázs, C | 2 |
| Stenszky, V | 1 |
| Kozma, L | 1 |
| Farid, NR | 1 |
| Chiovato, L | 1 |
| Hammond, LJ | 1 |
| Hanafusa, T | 1 |
| Pujol-Borrell, R | 1 |
| Doniach, D | 1 |
| Bottazzo, GF | 1 |
| Quaratino, S | 1 |
| Thorpe, CJ | 1 |
| Travers, PJ | 1 |
| Londei, M | 1 |
| Okugawa, T | 3 |
| Itoh, M | 3 |
| Murata, Y | 1 |
| Seo, H | 1 |
| Paschke, R | 2 |
| Eck, T | 1 |
| Herfurth, J | 1 |
| Usadel, KH | 2 |
| Di Cerbo, A | 2 |
| Di Paola, R | 2 |
| Bonati, M | 1 |
| Zingrillo, M | 1 |
| De Filippis, V | 2 |
| Corda, D | 2 |
| Metcalfe, RA | 1 |
| Davies, R | 1 |
| Weetman, AP | 1 |
| Menzaghi, C | 1 |
| McKenzie, JM | 3 |
| Zakarija, M | 2 |
| D'Amour, P | 1 |
| Joasoo, A | 1 |
| Bordan, L | 1 |
| Kovacs, L | 1 |
| Szerze, P | 1 |
| Sztojka, I | 1 |
| Leovey, A | 1 |
| Shimomura, N | 1 |
| Gafny, M | 1 |
| Ben-David, C | 1 |
| Sirkis, N | 1 |
| Gordon, A | 1 |
| Gross, J | 1 |
| Smeds, S | 1 |
| Jörtsö, E | 1 |
| Tegler, L | 1 |
| Teuber, J | 1 |
| Enger, I | 1 |
| Schmeidl, R | 1 |
| Schwedes, U | 1 |
| Fang, WY | 1 |
| Ye, WX | 1 |
| Taniguchi, S | 1 |
| Yoshida, A | 1 |
| Mashiba, H | 1 |
| Kawabe, Y | 1 |
| Eguchi, K | 1 |
| Shimomura, C | 1 |
| Mine, M | 1 |
| Otsubo, T | 1 |
| Ueki, Y | 1 |
| Tezuka, H | 1 |
| Nakao, H | 1 |
| Kawakami, A | 1 |
| Migita, K | 1 |
| Tao, TW | 1 |
| Leu, SL | 1 |
| Kriss, JP | 1 |
| Miyamoto, M | 1 |
| Sugawa, H | 1 |
| Kuma, K | 1 |
| Mori, T | 1 |
| Imura, H | 1 |
| Jin, S | 1 |
| Iida, Y | 1 |
| Kasagi, K | 1 |
| Tokuda, Y | 1 |
| Arai, K | 1 |
| Misaki, T | 1 |
| Konishi, J | 1 |
| Van Herle, AJ | 1 |
| Chopra, IJ | 1 |
| Folb, PI | 1 |
| Bank, H | 1 |
| DeGroot, LJ | 1 |
| Jaksina, S | 1 |
27 other studies available for thymidine and Graves Disease
| Article | Year |
|---|---|
Antibodies that promote thyroid growth. A distinct population of thyroid-stimulating autoantibodies.
Topics: Adult; Aged; Animals; Antibodies; Autoantibodies; Autoimmune Diseases; Biological Assay; Cell Line; | 1983 |
Specific suppressor T cell function in a patient with Graves' disease and her healthy identical twin.
Topics: Adult; Antigens, Surface; Cell Division; Concanavalin A; Diseases in Twins; Female; Graves Disease; | 1984 |
Detection of thyroid growth immunoglobulins (TGI) by [3H]-thymidine incorporation in cultured rat thyroid follicles.
Topics: Adult; Animals; Biological Assay; Culture Techniques; Female; Goiter; Goiter, Endemic; Graves Diseas | 1983 |
Similar antigenic surfaces, rather than sequence homology, dictate T-cell epitope molecular mimicry.
Topics: Amino Acid Sequence; Cell Division; Clone Cells; DNA; Epitopes; Graves Disease; HLA-D Antigens; Huma | 1995 |
Effect of aphidicolin on DNA synthesis in cultured human thyroid cells.
Topics: Aphidicolin; Cell Cycle; Cells, Cultured; DNA; Enzyme Inhibitors; Flow Cytometry; Graves Disease; Hu | 1995 |
Stimulation of proliferation and inhibition of function of xenotransplanted human thyroid tissue by epidermal growth factor.
Topics: Animals; Cell Division; Epidermal Growth Factor; Epithelial Cells; Epithelium; Graves Disease; Human | 1995 |
Subgroups of Graves' patients identified on the basis of the biochemical activities of their immunoglobulins.
Topics: Adult; Arachidonic Acid; Cyclic AMP; Female; Graves Disease; Humans; Immunoglobulin G; Male; Middle | 1995 |
Effect of monensin on DNA synthesis in cultured human thyroid cells.
Topics: Cell Cycle; Cells, Cultured; DNA; Endocytosis; Epidermal Growth Factor; Flow Cytometry; Golgi Appara | 1993 |
Analysis of fibroblast-stimulating activity in IgG from patients with Graves' dermopathy.
Topics: Cell Line; Cells, Cultured; DNA; Fibroblasts; Glucosamine; Glycosaminoglycans; Graves Disease; Human | 1993 |
Cyclooxygenase-dependent thyroid cell proliferation induced by immunoglobulins from patients with Graves' disease.
Topics: Animals; Cell Division; Cell Line; Cyclooxygenase Inhibitors; Graves Disease; Humans; Immunoglobulin | 1997 |
The long-acting thyroid stimulatory: is it of importance in Graves' disease.
Topics: Animals; Cyclic AMP; Female; Graves Disease; Humans; Immunoglobulin G; Long-Acting Thyroid Stimulato | 1975 |
Immunoblasts in Graves' disease.
Topics: Adolescent; Adult; Autoradiography; Female; Graves Disease; Humans; Lymphocytes; Male; Middle Aged; | 1977 |
Suppression of thyroid cell growth by serum IgG in Graves' disease.
Topics: Chromatography, DEAE-Cellulose; Epidermal Growth Factor; Gene Expression; Genes, fos; Graves Disease | 1992 |
The appearance in thyroidectomized mice of immunoglobulins that bind TSH and stimulate FRTL-5 thyrocytes.
Topics: Animals; Antibodies, Monoclonal; Cells, Cultured; DNA; Female; Graves Disease; Hybridomas; Immunoglo | 1992 |
Thyroid epithelial cell proliferation in xenotransplanted human toxic nodular goitre is increased by Graves' IgG.
Topics: Animals; Cell Division; Epithelium; Goiter, Nodular; Graves Disease; Immunoglobulin G; Iodine Radioi | 1991 |
Evidence for a role of anti-idiotypic antibodies in the induction of remission in Graves' disease.
Topics: Animals; Antibodies, Anti-Idiotypic; Autoantibodies; Binding, Competitive; Biological Assay; Cell Nu | 1990 |
Studies on suppressor T lymphocyte function in Graves' disease by 3H-thymidine interpolation.
Topics: Adolescent; Adult; Antithyroid Agents; Graves Disease; Humans; Middle Aged; T-Lymphocytes, Regulator | 1987 |
Direct effect of methimazole on rat thyroidal cell growth induced by thyrotropin and insulin-like growth factor I.
Topics: Animals; Biomechanical Phenomena; Bucladesine; Cell Division; Clone Cells; Cyclic AMP; Dose-Response | 1989 |
Interleukin-1 production and action in thyroid tissue.
Topics: Biological Availability; Cell Cycle; Cells, Cultured; Culture Media; Dinoprostone; Graves Disease; H | 1989 |
Biological activity of autoantibodies associated with Graves' dermopathy.
Topics: Animals; Autoantibodies; Cell Cycle; Cell Line; DNA; Female; Fibroblasts; Glycosaminoglycans; Graves | 1989 |
Analysis of epidermal growth factor (EGF) receptor and effect of EGF on the growth of cultured Graves' and non-neoplastic human thyroid cells.
Topics: Cell Division; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Graves Disease; Humans; Thy | 1989 |
Evidence supporting the identity in Graves' disease of thyroid-stimulating antibody and thyroid growth-promoting immunoglobulin G as assayed in FRTL5 cells.
Topics: Animals; Autoantibodies; Binding Sites, Antibody; Cell Line; Cyclic AMP; DNA; Graves Disease; Growth | 1988 |
Antibody-dependent cell-mediated growth inhibition of rat thyroid cells, FRTL-5, in patients with autoimmune thyroid diseases.
Topics: Adolescent; Adult; Aged; Antibodies; Cell Line; DNA; Female; Graves Disease; Growth Inhibitors; Huma | 1988 |
Thymic hyperplasia in Graves' disease.
Topics: Adult; Antithyroid Agents; Autoradiography; Culture Techniques; Female; Graves Disease; Humans; Long | 1971 |
Activated lymphocytes in the peripheral blood in acute hyperthyroidism (Graves' disease).
Topics: Adult; DNA; Female; Graves Disease; Humans; Immunity, Cellular; Leukocyte Count; Lymphocyte Activati | 1974 |
Instances of metabolic stimulation by antibody.
Topics: Adipose Tissue; Animals; Antibodies; Autoantibodies; DNA; Graves Disease; Guinea Pigs; Kidney; Long- | 1969 |
Observations on the role of circulating lymphocytes in thyroid auto-immunity.
Topics: Autoimmune Diseases; Carbon Isotopes; Cell Differentiation; Culture Techniques; DNA; Graves Disease; | 1969 |