thymidine has been researched along with Granulocytic Leukemia, Chronic in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " By contrast, methanol fixation followed by a brief treatment with the detergent Triton X-100 and immunostaining with either 19F4 or PC10 (but not with 19A2) combined a high sensitivity and specificity scores of the recognition of the 3H-thymidine-labeled cells: PC10 gave a more intense and, hence, more readable reaction." | 3.69 | PCNA immunopositivity index as a substitute to 3H-thymidine pulse-labeling index (TLI) in methanol-fixed human lymphocytes. ( Capel, P; Degraef, C; Del Bino, G; Feremans, W; Fokan, D; Galand, P; Morret, M, 1995) |
| "Leukemic blast cells isolated from chronic myeloid leukemia (CML) patients showed significant cell growth inhibition within twentyfour hours." | 1.31 | Boron compounds against human leukemic cells. ( Bhattacharya, M; Bhattacharya, S; Biswas, J; Das, M; Ghosh, M; Ghosh, P; Gomes, A; Mitra, S; Murmu, N; Sur, P; Vedasiromoni, JR, 2001) |
| "The response of normal and chronic myeloid leukemia (CML), CD34+ cells to human macrophage inflammatory protein-1 alpha (MIP-1 alpha or LD78) was assessed." | 1.29 | Macrophage inflammatory protein-1 alpha receptors are present on cells enriched for CD34 expression from patients with chronic myeloid leukemia. ( Chasty, RC; Lucas, GS; Owen-Lynch, PJ; Pierce, A; Whetton, AD, 1995) |
| "The cobalamin metabolism in chronic myelogenous leukemia (CML) was evaluated in 18 newly diagnosed and untreated patients by formiminoglutamic acid (FiGlu) and methyl malonic acid excretion (MMA) tests." | 1.29 | Cobalamin-dependent metabolism in chronic myelogenous leukemia determined by deoxyuridine suppression test and the formiminoglutamic acid and methylmalonate excretion in urine. ( Gimsing, P; Hippe, E, 1995) |
| "We cultured chronic myelogenous leukemia cells from the peripheral blood of several patients in blast crisis with three inhibitors of lipoxygenases: ETYA, and the more selective A63162 (Abbott) or SC41661A (Searle)." | 1.29 | Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase. ( Anderson, KM; Harris, JE; Jajeh, A; Levin, J; Seed, T, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (15.38) | 18.7374 |
| 1990's | 16 (61.54) | 18.2507 |
| 2000's | 5 (19.23) | 29.6817 |
| 2010's | 1 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naud, JS | 1 |
| Ghani, K | 1 |
| de Campos-Lima, PO | 1 |
| Caruso, M | 1 |
| Murmu, N | 2 |
| Ghosh, P | 2 |
| Gomes, A | 2 |
| Mitra, S | 2 |
| Das, M | 2 |
| Besra, SE | 1 |
| Majumdar, J | 1 |
| Bhattacharya, S | 2 |
| Sur, P | 2 |
| Vedasiromoni, JR | 2 |
| Gambacorti-Passerini, C | 1 |
| Zucchetti, M | 1 |
| Russo, D | 1 |
| Frapolli, R | 1 |
| Verga, M | 1 |
| Bungaro, S | 1 |
| Tornaghi, L | 1 |
| Rossi, F | 1 |
| Pioltelli, P | 1 |
| Pogliani, E | 1 |
| Alberti, D | 1 |
| Corneo, G | 1 |
| D'Incalci, M | 1 |
| van der Hoorn, MA | 1 |
| van Luxemburg-Heijs, SA | 1 |
| van Bergen, CA | 1 |
| Bongaerts, R | 1 |
| Willemze, R | 1 |
| Falkenburg, JH | 1 |
| HAMMOUDA, F | 1 |
| QUAGLINO, D | 1 |
| HAYHOE, FG | 1 |
| HAMPEL, KE | 1 |
| PALME, G | 1 |
| Chasty, RC | 1 |
| Lucas, GS | 1 |
| Owen-Lynch, PJ | 1 |
| Pierce, A | 1 |
| Whetton, AD | 2 |
| Walter, H | 1 |
| Galand, P | 1 |
| Del Bino, G | 1 |
| Morret, M | 1 |
| Capel, P | 1 |
| Degraef, C | 1 |
| Fokan, D | 1 |
| Feremans, W | 1 |
| Gimsing, P | 1 |
| Hippe, E | 1 |
| Cashman, JD | 2 |
| Eaves, AC | 3 |
| Eaves, CJ | 3 |
| Tosi, P | 1 |
| Visani, G | 1 |
| Ottaviani, E | 1 |
| Gamberi, B | 1 |
| Cenacchi, A | 1 |
| Tura, S | 1 |
| Wolpe, SD | 1 |
| Berczi, A | 1 |
| Barabas, K | 1 |
| Sizensky, JA | 1 |
| Faulk, WP | 1 |
| Anderson, KM | 1 |
| Levin, J | 1 |
| Jajeh, A | 1 |
| Seed, T | 1 |
| Harris, JE | 1 |
| Alama, A | 1 |
| Meazza, R | 1 |
| Barbieri, F | 1 |
| Biassoni, R | 1 |
| Mazzei, M | 1 |
| Nicolin, A | 1 |
| Szczylik, C | 1 |
| Skórski, T | 1 |
| Malaguarnera, L | 1 |
| Hetman, J | 1 |
| Chen, ST | 1 |
| Calabretta, B | 1 |
| Wark, G | 1 |
| Heyworth, CM | 1 |
| Spooncer, E | 1 |
| Czaplewski, L | 1 |
| Francis, JM | 1 |
| Dexter, TM | 1 |
| Benthin, M | 1 |
| Dallmann, I | 1 |
| Atzpodien, J | 1 |
| Ghosh, M | 1 |
| Bhattacharya, M | 1 |
| Biswas, J | 1 |
| Malik, F | 1 |
| Delgado, C | 1 |
| Knüsli, C | 1 |
| Irvine, AE | 1 |
| Fisher, D | 1 |
| Francis, GE | 1 |
| Otsuka, T | 1 |
| Humphries, RK | 1 |
| Hogge, DE | 1 |
| Chitnis, MP | 2 |
| Kamath, NS | 1 |
| Parekh, HK | 2 |
| Advani, SH | 2 |
| Callea, V | 1 |
| Morabito, F | 1 |
| Lista, P | 1 |
| Pegoraro, L | 1 |
| Cambrin, GR | 1 |
| Guerrasio, A | 1 |
| Saglio, G | 1 |
| Tassinari, A | 1 |
| Fierro, MT | 1 |
| Iacopino, P | 1 |
| Sokal, JE | 1 |
| Pauly, JL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-label Randomized Clinical Trial to Compare the Toxicities and Efficacy of Pharmacokinetically-guided and BSA Fixed Dosing Strategy of Docetaxel and Paclitaxel in Chinese Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma, and Breast Cancer Patie[NCT01891123] | 300 participants (Anticipated) | Interventional | 2013-06-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for thymidine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Benzamides; Blast Crisis; Cell Division; Female; H | 2003 |
25 other studies available for thymidine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Nilotinib and imatinib inhibit cytarabine cellular uptake: implications for combination therapy.
Topics: Benzamides; Cytarabine; Drug Therapy, Combination; Humans; Imatinib Mesylate; Leukemia, Myelogenous, | 2012 |
Antineoplastic effect of new boron compounds against leukemic cell lines and cells from leukemic patients.
Topics: Acute Disease; Antineoplastic Agents; Apoptosis; Boron Compounds; Cell Division; Guanidines; HL-60 C | 2002 |
The progenitor cell inhibition assay to measure the anti-leukemic reactivity of T cell clones against acute and chronic myeloid leukemia.
Topics: Acute Disease; Antigens, CD34; Cell Division; Clone Cells; Colony-Forming Units Assay; Cytokines; Cy | 2003 |
BLASTIC CRISIS IN CHRONIC GRANULOCYTIC LEUKAEMIA. CYTOCHEMICAL, CYTOGENETIC, AND AUTORADIOGRAPHIC STUDIES IN FOUR CASES.
Topics: Adolescent; Alkaline Phosphatase; Autoradiography; Bone Marrow Examination; Busulfan; Chromosome Abe | 1964 |
[CHROMOSOME STUDIES IN ACUTE AND CHRONIC MYELOCYTIC LEUKEMIA].
Topics: Autoradiography; Chromosome Aberrations; Chromosomes; DNA; Humans; Leukemia, Myelogenous, Chronic, B | 1964 |
Macrophage inflammatory protein-1 alpha receptors are present on cells enriched for CD34 expression from patients with chronic myeloid leukemia.
Topics: Antigens, CD34; Base Sequence; Cell Cycle; Chemokine CCL4; Colony-Forming Units Assay; Cytokines; DN | 1995 |
Analytical applications of partitioning: detection of differences or changes in surface properties of mammalian cell populations.
Topics: Animals; Carbon Radioisotopes; Cell Cycle; Cell Differentiation; Cell Membrane; Cell Separation; Cel | 1994 |
PCNA immunopositivity index as a substitute to 3H-thymidine pulse-labeling index (TLI) in methanol-fixed human lymphocytes.
Topics: Autoradiography; Cell Line; Histological Techniques; Humans; Immunohistochemistry; Ki-67 Antigen; Le | 1995 |
Cobalamin-dependent metabolism in chronic myelogenous leukemia determined by deoxyuridine suppression test and the formiminoglutamic acid and methylmalonate excretion in urine.
Topics: Adolescent; Adult; Aged; Bone Marrow; Bone Marrow Cells; Deoxyuridine; Female; Formiminoglutamic Aci | 1995 |
The tetrapeptide AcSDKP specifically blocks the cycling of primitive normal but not leukemic progenitors in long-term culture: evidence for an indirect mechanism.
Topics: Amino Acid Sequence; Bone Marrow; Bone Marrow Cells; Cell Adhesion; Cell Cycle; Chemokine CCL4; Colo | 1994 |
Synergistic cytotoxicity of AZT plus alpha and gamma interferon in chronic myeloid leukemia cell line K562.
Topics: Cell Division; Cell Line; Cell Survival; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Syner | 1993 |
Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cells.
Topics: Animals; Bone Marrow Cells; Cells, Cultured; Chemokine CCL3; Chemokine CCL4; CHO Cells; Cricetinae; | 1993 |
Adriamycin conjugates of human transferrin bind transferrin receptors and kill K562 and HL60 cells.
Topics: Cell Survival; DNA Replication; Doxorubicin; Humans; Iodine Radioisotopes; Kinetics; Leukemia, Myelo | 1993 |
Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetamides; Amides; Apoptosis; Base Sequence; Blast Crisis; Blood C | 1993 |
Antiproliferative effect of DNA polymerase alpha antisense oligodeoxynucleotides on breast cancer cells.
Topics: Adenocarcinoma; Base Sequence; Breast Neoplasms; Cell Division; DNA Polymerase II; DNA Replication; | 1993 |
Inhibition of in vitro proliferation of chronic myelogenous leukemia progenitor cells by c-myb antisense oligodeoxynucleotides.
Topics: Antigens, CD34; beta 2-Microglobulin; Blast Crisis; Cell Division; DNA Primers; Down-Regulation; Hem | 1996 |
Abl protein kinase abrogates the response of multipotent haemopoietic cells to the growth inhibitor macrophage inflammatory protein-1 alpha.
Topics: Calcium; Chemokine CCL3; Chemokine CCL4; DNA Replication; Growth Inhibitors; Hematopoietic Stem Cell | 1998 |
13cis- and all-trans retinoic acid have antiproliferative effects on CML cells and render IFN alpha antiproliferative potency after combined treatment in vitro.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Division; Drug Synergism | 2001 |
Boron compounds against human leukemic cells.
Topics: Apoptosis; Boron Compounds; Cell Division; DNA, Neoplasm; Guanidines; Humans; Leukemia, Myelogenous, | 2001 |
Polyethylene glycol (PEG)-modified granulocyte-macrophage colony-stimulating factor (GM-CSF) with conserved biological activity.
Topics: Animals; Biological Availability; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Chromatography, L | 1992 |
Lack of evidence for abnormal autocrine or paracrine mechanisms underlying the uncontrolled proliferation of primitive chronic myeloid leukemia progenitor cells.
Topics: Bone Marrow; Bone Marrow Cells; Cell Adhesion; Cell Cycle; Cell Division; Cells, Cultured; Hematopoi | 1991 |
Dipyrone enhances intracellular accumulation and cytotoxicity of adriamycin in human chronic myeloid leukemia cells.
Topics: Cell Survival; Dipyrone; DNA; Doxorubicin; Drug Evaluation, Preclinical; Drug Synergism; Humans; Leu | 1991 |
Abrogation of human chronic myeloid leukemia cells insensitivity to adriamycin and mitoxanthrone cytotoxicity by quinidine.
Topics: Cell Survival; DNA Replication; DNA, Neoplasm; Doxorubicin; Humans; Kinetics; Leukemia, Myelogenous, | 1990 |
Multilineage cell involvement in Ph1-negative, bcr-negative chronic myeloid leukemia.
Topics: Aged; Antigens, Differentiation, T-Lymphocyte; Biomarkers, Tumor; Cell Differentiation; Chromosome A | 1988 |
In vitro thymidine uptake by circulating leukocytes.
Topics: Adult; Biological Transport; Cells, Cultured; Hematologic Diseases; Humans; Leukemia; Leukemia, Lymp | 1974 |