Page last updated: 2024-11-06

thymidine and Glioma

thymidine has been researched along with Glioma in 139 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"This phase II study in recurrent high-grade glioma evaluated the response rate, toxicities, and time to treatment failure of high-dose carboplatin modulated by a 24-h infusion of thymidine (75 g/m(2))."9.10A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study. ( Chang, SM; Cloughesy, T; Fink, K; Greenberg, H; Hess, K; Junck, L; Kuhn, JG; Mehta, M; Nicolas, K; Prados, MD; Robins, HI; Schiff, D; Yung, WK, 2002)
" The purpose of this study was to evaluate (11)C-4DST uptake in patients with newly diagnosed glioma and to correlate the results with proliferative activity and tumor grade, in comparison with L-[methyl-(11)C]-methionine ((11)C-MET)."7.83Correlation of 4'-[methyl-(11)C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with (11)C-methionine uptake. ( Kawai, N; Kudomi, N; Maeda, Y; Nishiyama, Y; Tanaka, K; Toyohara, J; Yamamoto, H; Yamamoto, Y, 2016)
"The effect of genistein, a protein tyrosine kinase and topoisomerase II inhibitor, on the DNA synthesis rate was studied in 21 human glioma specimens obtained at routine craniotomies for tumor resection."7.75Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein. ( Cruz, MH; Ohlsson Lindblom, I; Siden, A; Yakisich, JS, 2009)
"The authors have previously shown that medroxyprogesterone acetate (MPA) inhibits growth and increases drug sensitivity in C6 glioma with myeloid bodies."7.74Medroxyprogesterone acetate induces c6 glioma chemosensitization via antidepressant-like lysosomal phospholipidosis/myelinosis in vitro. ( Altinoz, MA; Bilir, A; Del Maestro, RF; Gedikoglu, G; Ozcan, E; Ozdilli, K; Sav, A, 2007)
" This study examines the predictive value of positron emission tomography (PET) using [18F] fluorothymidine (FLT), an imaging biomarker of cell proliferation, in patients with recurrent malignant gliomas treated with bevacizumab in combination with irinotecan."7.74Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study. ( Chen, W; Cloughesy, T; Czernin, J; Delaloye, S; Geist, C; Lai, A; Phelps, ME; Pope, W; Satyamurthy, N; Sayre, J; Silverman, DH, 2007)
"We have recently shown that endothelin-1 activates two types of Ca2+-permeable nonselective cation channels (NSCC-1 and NSCC-2) in C6 glioma cells."7.71Effects of extracellular Ca2+ influx on endothelin-1-induced intracellular mitogenic cascades in C6 glioma cells. ( Hashimoto, N; Kawanabe, Y; Masaki, T, 2002)
" Recently, it has been shown that free geranylgeraniol (GG-OH) and farnesol (F-OH) can be utilized by C6 glioma cells for protein isoprenylation."7.70Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. ( Andres, DA; Crick, DC; Danesi, R; Macchia, M; Waechter, CJ, 1998)
"We have recently shown that glioma cell lines, as well as cells of human malignant gliomas in situ, synthesize tropoelastin."7.70Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells. ( Hinek, A; Jung, S; Rutka, JT, 1999)
"Tamoxifen has been shown to inhibit the proliferation of human gliomas in vitro."7.69A comparison of the relative chemosensitivity of human gliomas to tamoxifen and n-desmethyltamoxifen in vitro. ( Kristofik, MP; Randall, MS; Rehn, T; Selker, RG; Vertosick, FT, 1994)
"Treatment of rat C6 glioma cells with the tricyclic antidepressant desipramine induces opioid binding."7.69A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA. ( Barg, J; Belcheva, MM; Coscia, CJ; Johnson, FE; Levy, R; McHale, RJ; McLachlan, JA; Vogel, Z, 1994)
"The antiviral agents ganciclovir, 1-beta-D-arabinofuranosylthymine (araT), acyclovir, and 5-iodo-5'-amino-2',5'-dideoxyuridine were cytotoxic to rat C6 glioma cells expressing retrovirally transferred herpes simplex virus (HSV) type 1 thymidine kinase (TK) coding sequence, with concentrations that inhibited cell survival by 50% (IC50 values) of 0."7.69Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells. ( Breakefield, XO; Davidson, BL; Hughes, TL; Roessler, BJ; Shewach, DS; Zerbe, LK, 1994)
"The cytotoxic, antiproliferative, and radiosensitizing effects of thymidine (a nucleoside metabolite) were studied using the C6 glioma cell line in vitro."7.68Radiosensitization of C6 glioma by thymidine and 41.8 degrees C hyperthermia. ( Cohen, JD; Javid, MJ; Robins, HI, 1990)
"Effects of trifluoroacetic acid (TFA) on cell growth, DNA, glycoprotein, and dolichol-linked oligosaccharides synthesis and ribonucleotide triphosphate concentrations were examined in exponentially growing C6 murine glioma cells."7.68Effects of trifluoroacetic acid, a halothane metabolite, on C6 glioma cells. ( Ling, YH; Ma, TG; McClure, GD; Tseng, MT, 1990)
"8 degrees C hyperthermia were used to sensitize C6 glioma cells to carboplatin cytotoxicity in vitro."7.68Sensitization of C6 glioma to carboplatin cytotoxicity by hyperthermia and thymidine. ( Cohen, JD; Javid, MJ; Robins, HI, 1990)
" This study demonstrates that phorbol ester pretreatment of a LAK cell-sensitive glioma cell line (SNB-19) induced a significant decrease in the susceptibility of cells to LAK cell-mediated lysis."7.68Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity. ( Alterman, RL; Kornblith, PL; Maleci, A; Moskal, JR; Sundstrom, D, 1990)
" The mitogenic properties of epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) were examined in three human malignant glioma cell lines (T98G, U87, and U138)."7.68Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium. ( Kelly, RH; Kristofik, MP; Pollack, IF; Randall, MS; Selker, RG; Vertosick, FT, 1990)
"This paper studies the influence of uridine on the effects exerted by D-glucosamine in rat C6 glioma cells."7.67Uridine enhances the cytotoxic effect of D-glucosamine in rat C6 glioma cells. ( Calvaruso, G; Romano, N; Taibi, G; Tesoriere, G; Torregrossa, MV, 1986)
"The Na+ uptake into neuroblastoma x glioma hybrid cells was measured in Hepes-buffered EMEM containing 10% calf serum and 5 mM ouabain in the presence and absence of amiloride (1."7.66Membrane potential and sodium flux in neuroblastoma X glioma hybrid cells: effects of amiloride and serum. ( O'Donnell, ME; Villereal, ML, 1982)
"Cholecystokinin (CCK) is a gut-brain peptide has been described to be able to induce mitosis according to recent studies."5.35Cholecystokinin (CCK) and CCK receptor expression by human gliomas: Evidence for an autocrine/paracrine stimulatory loop. ( Adams, EF; Buchfelder, M; Oikonomou, E, 2008)
"This phase II study in recurrent high-grade glioma evaluated the response rate, toxicities, and time to treatment failure of high-dose carboplatin modulated by a 24-h infusion of thymidine (75 g/m(2))."5.10A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study. ( Chang, SM; Cloughesy, T; Fink, K; Greenberg, H; Hess, K; Junck, L; Kuhn, JG; Mehta, M; Nicolas, K; Prados, MD; Robins, HI; Schiff, D; Yung, WK, 2002)
" The purpose of this study was to evaluate (11)C-4DST uptake in patients with newly diagnosed glioma and to correlate the results with proliferative activity and tumor grade, in comparison with L-[methyl-(11)C]-methionine ((11)C-MET)."3.83Correlation of 4'-[methyl-(11)C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with (11)C-methionine uptake. ( Kawai, N; Kudomi, N; Maeda, Y; Nishiyama, Y; Tanaka, K; Toyohara, J; Yamamoto, H; Yamamoto, Y, 2016)
"The effect of genistein, a protein tyrosine kinase and topoisomerase II inhibitor, on the DNA synthesis rate was studied in 21 human glioma specimens obtained at routine craniotomies for tumor resection."3.75Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein. ( Cruz, MH; Ohlsson Lindblom, I; Siden, A; Yakisich, JS, 2009)
"The authors have previously shown that medroxyprogesterone acetate (MPA) inhibits growth and increases drug sensitivity in C6 glioma with myeloid bodies."3.74Medroxyprogesterone acetate induces c6 glioma chemosensitization via antidepressant-like lysosomal phospholipidosis/myelinosis in vitro. ( Altinoz, MA; Bilir, A; Del Maestro, RF; Gedikoglu, G; Ozcan, E; Ozdilli, K; Sav, A, 2007)
" This study examines the predictive value of positron emission tomography (PET) using [18F] fluorothymidine (FLT), an imaging biomarker of cell proliferation, in patients with recurrent malignant gliomas treated with bevacizumab in combination with irinotecan."3.74Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study. ( Chen, W; Cloughesy, T; Czernin, J; Delaloye, S; Geist, C; Lai, A; Phelps, ME; Pope, W; Satyamurthy, N; Sayre, J; Silverman, DH, 2007)
" The human glioma cell lines U87 MG, U251 MG and U138 MG were treated with purines and pyrimidines for 24 or 48 h and proliferation was measured by [3H]-thymidine incorporation, flow cytometry and cell counting."3.72Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines. ( Bernardi, A; Horn, AP; Jacques-Silva, MC; Lenz, G; Morrone, FB; Rodnight, R; Schwartsmann, G, 2003)
"We have recently shown that endothelin-1 activates two types of Ca2+-permeable nonselective cation channels (NSCC-1 and NSCC-2) in C6 glioma cells."3.71Effects of extracellular Ca2+ influx on endothelin-1-induced intracellular mitogenic cascades in C6 glioma cells. ( Hashimoto, N; Kawanabe, Y; Masaki, T, 2002)
" Recently, it has been shown that free geranylgeraniol (GG-OH) and farnesol (F-OH) can be utilized by C6 glioma cells for protein isoprenylation."3.70Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. ( Andres, DA; Crick, DC; Danesi, R; Macchia, M; Waechter, CJ, 1998)
" In the present study, butyrate treatment caused decreases in thymidine incorporation in the early passages (45-60) of C6 glioma cells."3.70Alterations in Ca2+ signaling, and c-fos and nur77 expression are associated with sodium butyrate-induced differentiation of C6 glioma cell. ( Jang, TH; Sun, SH, 2000)
"We have recently shown that glioma cell lines, as well as cells of human malignant gliomas in situ, synthesize tropoelastin."3.70Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells. ( Hinek, A; Jung, S; Rutka, JT, 1999)
"Treatment of rat C6 glioma cells with the tricyclic antidepressant desipramine induces opioid binding."3.69A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA. ( Barg, J; Belcheva, MM; Coscia, CJ; Johnson, FE; Levy, R; McHale, RJ; McLachlan, JA; Vogel, Z, 1994)
"Tamoxifen has been shown to inhibit the proliferation of human gliomas in vitro."3.69A comparison of the relative chemosensitivity of human gliomas to tamoxifen and n-desmethyltamoxifen in vitro. ( Kristofik, MP; Randall, MS; Rehn, T; Selker, RG; Vertosick, FT, 1994)
"The antiviral agents ganciclovir, 1-beta-D-arabinofuranosylthymine (araT), acyclovir, and 5-iodo-5'-amino-2',5'-dideoxyuridine were cytotoxic to rat C6 glioma cells expressing retrovirally transferred herpes simplex virus (HSV) type 1 thymidine kinase (TK) coding sequence, with concentrations that inhibited cell survival by 50% (IC50 values) of 0."3.69Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells. ( Breakefield, XO; Davidson, BL; Hughes, TL; Roessler, BJ; Shewach, DS; Zerbe, LK, 1994)
"Opioid agonists inhibit DNA synthesis in C6 rat glioma cells that express opioid receptors, induced by desipramine (DMI)."3.69Opioids inhibit endothelin-mediated DNA synthesis, phosphoinositide turnover, and Ca2+ mobilization in rat C6 glioma cells. ( Barg, J; Belcheva, MM; Coscia, CJ; Johnson, FE; Levy, R; McHale, RJ; Saya, D; Vogel, Z; Zimlichman, R, 1994)
"Transfection of a human dopamine D3 receptor cDNA in a neuroblastoma-glioma hybrid cell line (NG 108-15) provided clonal cell lines stably expressing up to 600 fmol per mg protein of [125I]iodosulpiride binding sites."3.69Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line. ( Dimitriadou, V; Griffon, N; Lévesque, D; Martres, MP; Pilon, C; Schwartz, JC; Sokoloff, P, 1994)
"To shed light on the metabolic changes in glioma following therapy, uptake changes among 18F-fluoro-2'-deoxyuridine (18FUdR), 14C-thymidine (dThd), 14C-methionine (Met) and 3H-deoxyglucose (DG) in glioma model after chemotherapy were studied, as a means for interpreting clinical PET results, together with the changes in the bromodeoxyuridine (BUdR) labeling index."3.68Metabolic changes of glioma following chemotherapy: an experimental study using four PET tracers. ( Ishiwata, K; Kameyama, M; Katakura, R; Sato, K; Yoshimoto, T, 1992)
"Direct cell counting and extent of [3H]thymidine incorporation demonstrated valproate to inhibit C6 glioma proliferation rate in a dose-dependent manner with a 1 mM concentration achieving 50% inhibition."3.68The anticonvulsant valproate teratogen restricts the glial cell cycle at a defined point in the mid-G1 phase. ( Martin, ML; Regan, CM, 1991)
"8 degrees C hyperthermia were used to sensitize C6 glioma cells to carboplatin cytotoxicity in vitro."3.68Sensitization of C6 glioma to carboplatin cytotoxicity by hyperthermia and thymidine. ( Cohen, JD; Javid, MJ; Robins, HI, 1990)
"Effects of trifluoroacetic acid (TFA) on cell growth, DNA, glycoprotein, and dolichol-linked oligosaccharides synthesis and ribonucleotide triphosphate concentrations were examined in exponentially growing C6 murine glioma cells."3.68Effects of trifluoroacetic acid, a halothane metabolite, on C6 glioma cells. ( Ling, YH; Ma, TG; McClure, GD; Tseng, MT, 1990)
"The cytotoxic, antiproliferative, and radiosensitizing effects of thymidine (a nucleoside metabolite) were studied using the C6 glioma cell line in vitro."3.68Radiosensitization of C6 glioma by thymidine and 41.8 degrees C hyperthermia. ( Cohen, JD; Javid, MJ; Robins, HI, 1990)
" The mitogenic properties of epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) were examined in three human malignant glioma cell lines (T98G, U87, and U138)."3.68Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium. ( Kelly, RH; Kristofik, MP; Pollack, IF; Randall, MS; Selker, RG; Vertosick, FT, 1990)
"In the present study the effect of cocaine on thymidine, uridine and leucine incorporation was assessed in primary cortical glial and C6 glioma cells."3.68Effect of cocaine on macromolecular syntheses and cell proliferation in cultured glial cells. ( Bansinath, M; Garg, UC; Turndorf, H, 1993)
" This study demonstrates that phorbol ester pretreatment of a LAK cell-sensitive glioma cell line (SNB-19) induced a significant decrease in the susceptibility of cells to LAK cell-mediated lysis."3.68Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity. ( Alterman, RL; Kornblith, PL; Maleci, A; Moskal, JR; Sundstrom, D, 1990)
" The potential proliferative activity of these different neoplasms, evaluated as in vitro 3H-thymidine labeling index (LI), has been determined in 46 mature astrocytomas, 19 anaplasic astrocytomas, 25 glioblastomas, 5 cystic craniopharyngiomas, 6 metastatic tumors, 4 primary C."3.67Cell kinetic investigations in brain tumors studied by serial stereotactic biopsy. ( Allegranza, A; Broggi, G; Costa, A; Ferraresi, S; Franzini, A; Giorgi, C, 1989)
"The effects of 2 specific calcium channel blockers, verapamil and nimodipine, on the proliferation of human glioma tumour cells were investigated in vitro."3.67Inhibitory effect of calcium channel blockers on proliferation of human glioma cells in vitro. ( Kunert-Radek, J; Lyson, K; Pawlikowski, M; Radek, A; Stepien, H, 1989)
"To determine whether tumor necrosis factor is of potential value for the treatment of human malignant gliomas, we studied the effects of human recombinant tumor necrosis factor (rTNF-alpha) on the morphology, incorporation of tritiated thymidine, and proliferation of 5 established cell lines derived from human malignant gliomas and 3 normal human brain cell cultures."3.67The effects of human recombinant tumor necrosis factor on glioma-derived cell lines: cellular proliferation, cytotoxicity, morphological and radioreceptor studies. ( Aggarwal, BB; Bar-Shiva, E; Berens, ME; Bodell, WJ; Eessalu, TE; Giblin, JR; McCulloch, JR; Rosenblum, ML; Rutka, JT; Tokuda, K, 1988)
"The effects of several benzodiazepines (diazepam, clonazepam, Ro 15-1788 and Ro 5-4864) on cell proliferation of 2 human gliomas were estimated in vitro by means of [3H]-thymidine uptake assay."3.67Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro. ( Kunert-Radek, J; Pawlikowski, M; Radek, A; Stepien, H, 1988)
"This paper studies the influence of uridine on the effects exerted by D-glucosamine in rat C6 glioma cells."3.67Uridine enhances the cytotoxic effect of D-glucosamine in rat C6 glioma cells. ( Calvaruso, G; Romano, N; Taibi, G; Tesoriere, G; Torregrossa, MV, 1986)
"The Na+ uptake into neuroblastoma x glioma hybrid cells was measured in Hepes-buffered EMEM containing 10% calf serum and 5 mM ouabain in the presence and absence of amiloride (1."3.66Membrane potential and sodium flux in neuroblastoma X glioma hybrid cells: effects of amiloride and serum. ( O'Donnell, ME; Villereal, ML, 1982)
"The penetration of [3H]thymidine, [3H]D-leucine, [125I]albumin, and the drugs [3H]5-fluorouracil and [3H]vinblastine into human glioma spheroids (in vitro tumor models) was studied by a method based on rapid freezing, freeze drying, vapor fixation, wax embedding, dry sectioning, and contact autoradiography."3.66Penetration of substances into tumor tissue--a methodological study on cellular spheroids. ( Carlsson, J; Malmqvist, M; Nederman, T, 1981)
"Twelve patients with gliomas received 3H-thymidine intraarterially in combination with an i."3.66The stathmokinetic (mitostatic) effect of vincristine and vinblastine on human gliomas. ( Hoshino, T; Muraoka, I; Wilson, CB, 1979)
" In the present study, however, changes in intracellular cyclic AMP level in several lines of cultured cells (normal 3T3 and SV40 and polyomavirus-transformed 3T3 cells; 3T6, C6 GLIOMA, MOUSE L, and Novikoff rat hepatoma cells) by treatment with papaverine, prostaglandine E1 or isoproterenol did not correlate with the inhibition of the uridine, hypoxanthine or deoxyglucose transport rates by these chemicals."3.65Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells. ( Plagemann, PG; Sheppard, JR, 1975)
"Four patients received 3H-thymidine 4 to 7 days and vinblastine 4 to 6 hours prior to operation for recurrent malignant gliomas (three glioblastomas and one anaplastic astrocytoma)."3.65Chemotherapeutic implications of growth fraction and cell cycle time in glioblastomas. ( Barker, M; Hoshino, T; Rosenblum, ML; Wilson, CB, 1975)
"Tritiated thymidine (3-H-T) was administered intravenously to seven patients with cerebral gliomas."3.65Gemistocytic astrocytes in gliomas. An autoradiographic study. ( Ellis, WG; Hoshino, T; Wilson, BC, 1975)
"The amino sugar, D-glucosamine, inhibits the preformed route of thymidine metabolism in rat C6 glioma cells."3.65The inhibition of thymidine metabolism in tumor cells treated with D-glucosamine. ( Friedman, SJ; Kimball, T; Skehan, PJ; Trotter, CD, 1977)
"Cholecystokinin (CCK) is a gut-brain peptide has been described to be able to induce mitosis according to recent studies."1.35Cholecystokinin (CCK) and CCK receptor expression by human gliomas: Evidence for an autocrine/paracrine stimulatory loop. ( Adams, EF; Buchfelder, M; Oikonomou, E, 2008)
"Gliomas are tumors derived from glia or their precursors within the central nervous system."1.34STI1 promotes glioma proliferation through MAPK and PI3K pathways. ( Chiarini, LB; Erlich, RB; Kahn, SA; Lima, FR; Linden, R; Martins, RA; Martins, VR; Moura Neto, V; Muras, AG, 2007)
" Therefore, we have investigated the effects of the orally bioavailable Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG) on the radiosensitivity of human tumor cells in vitro and grown as tumor xenografts."1.32Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin. ( Brady, KJ; Bull, EE; Burgan, WE; Camphausen, K; Carter, DJ; Cerra, MA; Dote, H; Hollingshead, MG; Oswald, KA; Tofilon, PJ, 2004)
"Malignant gliomas are frequent and the prognosis is poor."1.31Interferon gamma inhibits proliferation and hyaluronic acid adhesion of human malignant glioma cells in vitro. ( Domula, M; Knüpfer, H; Knüpfer, MM; Van Gool, S; Wolff, JE, 2000)
" In dose-response studies, IGF-I mRNA levels decreased to 27% of control levels (cells maintained in serum-free media) after treatment with 5 ng/ml dexamethasone, while half-maximal inhibition was achieved with approximately 0."1.28Regulation of insulin-like growth factor I production in rat C6 glioma cells: possible role as an autocrine/paracrine growth factor. ( Karpen, CW; Lorentzen, LR; Lowe, WL; Meyer, T, 1992)
" The dose-response curve for choline generation and DNA synthesis were comparable."1.28Activation of phospholipase D by platelet-derived growth factor (PDGF) in rat C6 glioma cells: possible role in mitogenic signal transduction. ( Nakashima, T; Nozawa, Y; Okano, Y; Sakai, N; Yamada, H; Zhang, W, 1992)
"We studied brain tumors induced by avian sarcoma virus and ethylnitrosourea, and transplanted RG-2 intracerebral and subcutaneous gliomas."1.27Regional thymidine transport and incorporation in experimental brain and subcutaneous tumors. ( Blasberg, R; Fenstermacher, J; Groothuis, D; Molnar, P; Owens, E; Zaharko, D, 1984)

Research

Studies (139)

TimeframeStudies, this research(%)All Research%
pre-199055 (39.57)18.7374
1990's58 (41.73)18.2507
2000's24 (17.27)29.6817
2010's2 (1.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takami, Y1
Yamamoto, Y2
Ueno, M1
Chiba, Y1
Norikane, T1
Hatakeyama, T1
Miyake, K1
Toyohara, J2
Nishiyama, Y2
Tanaka, K1
Maeda, Y1
Yamamoto, H1
Kudomi, N1
Kawai, N1
Yakisich, JS1
Ohlsson Lindblom, I1
Siden, A1
Cruz, MH1
Sun, YX1
Wright, HT1
Janciauskiene, S1
Yoon, JT1
Palazzo, AF1
Xiao, D1
Delohery, TM1
Warburton, PE1
Bruce, JN1
Thompson, WJ1
Sperl, G1
Whitehead, C1
Fetter, J1
Pamukcu, R1
Gundersen, GG1
Weinstein, IB1
D'Onofrio, M1
Arcella, A1
Bruno, V1
Ngomba, RT1
Battaglia, G1
Lombari, V1
Ragona, G1
Calogero, A1
Nicoletti, F1
Ross, BD1
Chenevert, TL1
Garwood, M1
Kim, B1
Stegman, LD1
Ben-Yoseph, O1
Zwolshen, J1
Rehemtulla, A1
Sunkara, PS1
Chou, RC1
Langan, TJ1
Morrone, FB1
Jacques-Silva, MC1
Horn, AP1
Bernardi, A1
Schwartsmann, G1
Rodnight, R1
Lenz, G1
Bauréus-Koch, C1
Nyberg, G1
Widegren, B1
Salford, LG1
Persson, BR1
Barth, RF2
Yang, W2
Al-Madhoun, AS1
Johnsamuel, J1
Byun, Y2
Chandra, S1
Smith, DR1
Tjarks, W2
Eriksson, S2
Bull, EE1
Dote, H1
Brady, KJ1
Burgan, WE1
Carter, DJ1
Cerra, MA1
Oswald, KA1
Hollingshead, MG1
Camphausen, K1
Tofilon, PJ1
Guo, M1
Roman, RJ1
Falck, JR1
Edwards, PA1
Scicli, AG1
Davis, FB1
Tang, HY1
Shih, A1
Keating, T1
Lansing, L1
Hercbergs, A1
Fenstermaker, RA1
Mousa, A1
Mousa, SA1
Davis, PJ1
Lin, HY1
Thirumamagal, BT1
Altinoz, MA1
Gedikoglu, G1
Sav, A1
Ozcan, E1
Ozdilli, K1
Bilir, A1
Del Maestro, RF1
Erlich, RB1
Kahn, SA1
Lima, FR1
Muras, AG1
Martins, RA1
Linden, R1
Chiarini, LB1
Martins, VR1
Moura Neto, V1
Chen, W1
Delaloye, S1
Silverman, DH1
Geist, C1
Czernin, J1
Sayre, J1
Satyamurthy, N1
Pope, W1
Lai, A1
Phelps, ME1
Cloughesy, T2
Oikonomou, E1
Buchfelder, M1
Adams, EF1
Lapham, LW1
Froelich, JS1
Leuchtenberger, C1
Charlton, RR1
Venter, JC1
Mary, JY1
Acker, H1
Holtermann, G1
Carlsson, J4
Nederman, T2
Korosue, K1
Takeshita, I2
Mannoji, H1
Fukui, M2
Berdel, WE1
Greiner, E1
Fink, U1
Zänker, KS1
Stavrou, D1
Trappe, A1
Fahlbusch, R1
Reichert, A1
Rastetter, J1
Molnar, P1
Groothuis, D1
Blasberg, R1
Zaharko, D1
Owens, E1
Fenstermacher, J1
DiSorbo, DM1
Litwack, G1
O'Donnell, ME1
Villereal, ML1
Malmqvist, M2
Wiezsaecker, M1
Hoshino, T8
Kobayashi, S1
Nakada, S1
Imura, N1
Saqr, HE1
Lee, MC1
Burkman, AM1
Yates, AJ1
Ikemoto, H1
Tani, E1
Matsumoto, T1
Nakano, A1
Furuyama, J1
Bradshaw, SL1
Naus, CC1
Zhu, D1
Kidder, GM1
D'Ercole, AJ1
Han, VK1
Garg, UC1
Turndorf, H1
Bansinath, M1
Shewach, DS2
Zerbe, LK1
Hughes, TL1
Roessler, BJ1
Breakefield, XO1
Davidson, BL1
Amoureux, MC1
Wurch, T1
Pauwels, PJ1
Bagaglio, DM1
Hait, WN1
Barg, J2
Belcheva, MM2
Zimlichman, R1
Levy, R2
Saya, D1
McHale, RJ2
Johnson, FE2
Coscia, CJ2
Vogel, Z2
Pilon, C1
Lévesque, D1
Dimitriadou, V1
Griffon, N1
Martres, MP1
Schwartz, JC1
Sokoloff, P1
Vertosick, FT3
Selker, RG3
Randall, MS3
Kristofik, MP3
Rehn, T1
Lin, Y1
Leskawa, KC1
Raile, K1
Höflich, A1
Kessler, U1
Yang, Y1
Pfuender, M1
Blum, WF1
Kolb, H1
Schwarz, HP1
Kiess, W1
Matsuda, T1
Murata, Y1
Kawamura, N1
Hayashi, M1
Tamada, K1
Takuma, K1
Maeda, S1
Baba, A1
McLachlan, JA1
Sakuma, S1
Sawamura, Y1
Tada, M1
Aida, T1
Abe, H1
Suzuki, K1
Taniguchi, N1
Nerurkar, VR1
Wakayama, I1
Rowe, T1
Yanagihara, R1
Garruto, RM1
Kurimoto, M1
Nogami, K1
Ogiichi, T1
Nishijima, M1
Takaku, A1
Kaufmann, R2
Henklein, P2
Nowak, G2
Jeitner, TM1
Renton, FJ1
Sun, SH2
Ou, HC1
Jang, TH2
Lin, LB1
Huang, HM1
Yamamoto, S1
Wakimoto, H1
Aoyagi, M1
Hirakawa, K1
Hamada, H1
Kenny, JS1
Kisaalita, WS1
Rowland, G1
Thai, C1
Foutz, T1
Wu, G1
Lu, ZH1
Alfinito, P1
Ledeen, RW1
Abaza, MS1
Narayan, RK1
Atassi, MZ1
Rubsam, LZ1
Crick, DC1
Andres, DA1
Danesi, R1
Macchia, M1
Waechter, CJ1
Caronti, B1
Buttarelli, FR1
Giustini, S1
Calderaro, C1
Calandriello, L1
Calvieri, S1
Palladini, G1
Schafberg, H1
Zieger, M1
Etienne, MC1
Formento, JL1
Lebrun-Frenay, C1
Gioanni, J1
Chatel, M1
Paquis, P1
Bernard, C1
Courdi, A1
Bensadoun, RJ1
Pignol, JP1
Francoual, M1
Grellier, P1
Frenay, M1
Milano, G1
Miccoli, L1
Beurdeley-Thomas, A1
De Pinieux, G1
Sureau, F1
Oudard, S1
Dutrillaux, B1
Poupon, MF1
Hinek, A1
Jung, S1
Rutka, JT2
Watanabe, T1
Katayama, Y1
Kimura, S1
Yoshino, A1
Moeller, I1
Albiston, AL1
Lew, RA1
Mendelsohn, FA1
Chai, SY1
Knüpfer, MM1
Knüpfer, H1
Van Gool, S1
Domula, M1
Wolff, JE1
Hedberg, KM1
Dellheden, B1
Wikstrand, CJ1
Fredman, P1
Friend, KE1
Khandwala, HM1
Flyvbjerg, A1
Hill, H1
Li, J1
McCutcheon, IE1
Kawanabe, Y1
Hashimoto, N1
Masaki, T1
Robins, HI3
Chang, SM1
Prados, MD1
Yung, WK2
Hess, K1
Schiff, D1
Greenberg, H1
Fink, K1
Nicolas, K1
Kuhn, JG1
Junck, L1
Mehta, M1
Chacko, MS1
Ma, X1
Adamo, ML1
Sheppard, JR1
Plagemann, PG1
Wilson, BC1
Ellis, WG1
Sato, S1
Sugimura, T1
Yoda, K1
Fujimura, S1
Hasegawa, H1
Shapiro, WR2
Posner, JB1
Basler, G1
Wilson, CB4
Muraoka, I1
Schick, P1
Steinbach, KH1
Friedman, SJ1
Trotter, CD1
Kimball, T1
Skehan, PJ1
Maker, HS1
Syed, HH1
Lehrer, GM1
Rosenblum, ML3
Barker, M3
Gross, JL1
Herblin, WF1
Eidsvoog, K1
Horlick, R1
Brem, SS1
Zhang, W2
Nakashima, T1
Sakai, N2
Yamada, H2
Okano, Y2
Nozawa, Y2
Sánchez-Gómez, MV1
Conde-Guerri, B1
Sinués-Porta, E1
Matute, C1
Sato, K1
Kameyama, M1
Ishiwata, K1
Katakura, R1
Yoshimoto, T1
Shields, AF1
Graham, MM1
Kozawa, SM1
Kozell, LB1
Link, JM1
Swenson, ER1
Spence, AM1
Bassingthwaighte, JB1
Krohn, KA1
Lowe, WL1
Meyer, T1
Karpen, CW1
Lorentzen, LR1
Cleary, SF1
Liu, LM1
Cao, G1
Slepko, NG1
Kozlova, MV1
Tung, PS1
Fritz, IB1
Cook, JA1
Glass, J1
Lebovics, R1
Bobo, H1
Pass, H1
DeLaney, TF1
Oldfield, EH1
Mitchell, JB1
Glatstein, E1
Goffman, TE1
Martin, ML2
Regan, CM3
Nishimura, T1
Nakamura, Y1
Takeuchi, Y1
Gao, XH1
Tokuda, Y1
Okumura, K1
Habu, S1
Gáti, I1
Bergström, M1
Muhr, C1
Yokomori, N1
Iwasa, Y1
Aida, K1
Inoue, M1
Tawata, M1
Onaya, T1
Fu, T1
Hirayama, H1
Takenaka, K1
Mercer, WE1
Shields, MT1
Amin, M1
Sauve, GJ1
Appella, E1
Romano, JW1
Ullrich, SJ1
Ikezaki, K1
Black, KL1
Pollack, IF2
Kelly, RH2
Merrill, MJ1
Edwards, NA1
Cohen, JD2
Javid, MJ2
Ma, TG1
Ling, YH1
McClure, GD1
Tseng, MT1
Maleci, A1
Alterman, RL1
Sundstrom, D1
Kornblith, PL1
Moskal, JR1
Inoue, T1
Iwaki, T1
Franzini, A2
Ferraresi, S1
Giorgi, C1
Costa, A2
Allegranza, A2
Broggi, G2
Kunert-Radek, J2
Stepien, H2
Radek, A2
Lyson, K1
Pawlikowski, M2
Giblin, JR1
Berens, ME1
Bar-Shiva, E1
Tokuda, K1
McCulloch, JR1
Eessalu, TE1
Aggarwal, BB1
Bodell, WJ1
Maxwell, K1
Berliner, JA1
Cancilla, PA1
Barnes, DM1
Yoshida, S1
Minakawa, T1
Takai, N1
Tanaka, R1
Westphal, M1
Neuss, M1
Herrmann, HD1
Melcarne, A1
Ventura, L1
Calvaruso, G1
Taibi, G1
Torregrossa, MV1
Romano, N1
Tesoriere, G1
Vrignaud, P1
Londos-Gagliardi, D1
Robert, J1
Pertuiset, B1
Dougherty, D1
Cromeyer, C1
Berger, M1
Hlatky, L1
Alpen, EL1
Westermark, B1
Takahashi, T1
Takeno, Y1
Takaki, R1
Kajiyama, T1
Takii, M1
Citoler, P2
Thomas, C2
Sano, K1
Nagai, M1
Goffinet, DR1
Brown, JM1
Bagshaw, MA1
Kaplan, HS1
Aksiutina, MS2
Lipchina, LP2
Iablonovskaia, LIa2
Boldrey, EB1
Fewer, D1
Waghe, M1
Kumar, S1
Steward, JK1
Kanno, T1
Nakazawa, T1
Kato, Y1
Catterall, WA1
Nirenberg, M1
Chen, TT1
Mealey, J1
Drechsler, HJ1
Grossi-Paoletti, E1
Paoletti, P1
Pezzotta, S1
Schiffer, D1
Fabiani, A1
Downey, R1
Spryshkova, NA1
Holmström, T1
Saksela, E1
Nyström, S1
Saxén, E1

Reviews

2 reviews available for thymidine and Glioma

ArticleYear
Normal human granulopoiesis revisited. I. Blood data.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 1984, Volume: 38, Issue:1

    Topics: Blood Cell Count; Glioma; Granulocytes; Half-Life; Hematopoiesis; Hematopoietic Stem Cells; Humans;

1984
In vitro chemosensitivity testing and its clinical application in human gliomas.
    Neurosurgical review, 1989, Volume: 12, Issue:3

    Topics: Amino Acids; Antineoplastic Agents; Biological Factors; Brain Neoplasms; Colorimetry; Coloring Agent

1989

Trials

1 trial available for thymidine and Glioma

ArticleYear
A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study.
    Neuro-oncology, 2002, Volume: 4, Issue:2

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Drug Admi

2002

Other Studies

136 other studies available for thymidine and Glioma

ArticleYear
Correlation of 4'-[methyl-
    Annals of nuclear medicine, 2018, Volume: 32, Issue:9

    Topics: Aged; Biological Transport; Equilibrative Nucleoside Transporter 1; Female; Gene Expression Regulati

2018
Correlation of 4'-[methyl-(11)C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with (11)C-methionine uptake.
    Annals of nuclear medicine, 2016, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biological Transport; Brain Neoplasms; Carbon Radioisoto

2016
Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein.
    Oncology reports, 2009, Volume: 22, Issue:3

    Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Brain Neoplasms; DNA; Dose-Response Relationship, Dru

2009
Glioma cell activation by Alzheimer's peptide Abeta1-42, alpha1-antichymotrypsin, and their mixture.
    Cellular and molecular life sciences : CMLS, 2002, Volume: 59, Issue:10

    Topics: alpha 1-Antichymotrypsin; Amyloid beta-Peptides; Base Sequence; DNA Primers; DNA, Neoplasm; Gene Exp

2002
CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells.
    Molecular cancer therapeutics, 2002, Volume: 1, Issue:6

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 3T3 Cells; Animals; Antine

2002
Pharmacological blockade of mGlu2/3 metabotropic glutamate receptors reduces cell proliferation in cultured human glioma cells.
    Journal of neurochemistry, 2003, Volume: 84, Issue:6

    Topics: Amino Acids; Bridged Bicyclo Compounds, Heterocyclic; Cell Division; Cells, Cultured; Cyclin D1; Cyc

2003
Evaluation of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on the 9L rat brain tumor model using MRI.
    NMR in biomedicine, 2003, Volume: 16, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Su

2003
In vitro synchronization of mammalian astrocytic cultures by serum deprivation.
    Brain research. Brain research protocols, 2003, Volume: 11, Issue:3

    Topics: Animals; Animals, Newborn; Astrocytes; Bromodeoxyuridine; Cell Cycle; Cells, Cultured; Culture Media

2003
Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.
    Journal of neuro-oncology, 2003, Volume: 64, Issue:3

    Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Brain Neoplasms; Cell Division; DNA; Extra

2003
Radiation sterilisation of cultured human brain tumour cells for clinical immune tumour therapy.
    British journal of cancer, 2004, Jan-12, Volume: 90, Issue:1

    Topics: Brain Neoplasms; Cell Division; Cell Survival; Cesium Radioisotopes; Genetic Therapy; Glioblastoma;

2004
Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors.
    Cancer research, 2004, Sep-01, Volume: 64, Issue:17

    Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Division; Glioma; Hum

2004
Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Dec-01, Volume: 10, Issue:23

    Topics: Administration, Oral; Animals; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Com

2004
Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:2

    Topics: Amidines; Antineoplastic Agents; Arachidonic Acid; Blotting, Western; Brain Neoplasms; Cell Line, Tu

2005
Acting via a cell surface receptor, thyroid hormone is a growth factor for glioma cells.
    Cancer research, 2006, Jul-15, Volume: 66, Issue:14

    Topics: Animals; Cell Growth Processes; Cell Line, Tumor; Enzyme Activation; Glioma; Integrin alphaVbeta3; M

2006
Preparation and biological evaluation of 10B-enriched 3-[5-{2-(2,3-dihydroxyprop-1-yl)-o-carboran-1-yl}pentan-1-yl]thymidine (N5-2OH), a new boron delivery agent for boron neutron capture therapy of brain tumors.
    Journal of medicinal chemistry, 2006, Sep-07, Volume: 49, Issue:18

    Topics: Animals; Binding Sites; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Calcium; Gl

2006
Medroxyprogesterone acetate induces c6 glioma chemosensitization via antidepressant-like lysosomal phospholipidosis/myelinosis in vitro.
    The International journal of neuroscience, 2007, Volume: 117, Issue:10

    Topics: Animals; Antidepressive Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplast

2007
STI1 promotes glioma proliferation through MAPK and PI3K pathways.
    Glia, 2007, Volume: 55, Issue:16

    Topics: Astrocytes; Binding Sites; Cell Line, Tumor; Cell Proliferation; Glioma; Heat-Shock Proteins; Humans

2007
Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2007, Oct-20, Volume: 25, Issue:30

    Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem

2007
Cholecystokinin (CCK) and CCK receptor expression by human gliomas: Evidence for an autocrine/paracrine stimulatory loop.
    Neuropeptides, 2008, Volume: 42, Issue:3

    Topics: Autocrine Communication; Brain Neoplasms; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Cell Prol

2008
Further in vitro studies of large cell glioblastomas. 1. Nuclear and nucleolar RNA. 2. Autoradiographic studies of the cell division cycle.
    Journal of neuropathology and experimental neurology, 1967, Volume: 26, Issue:1

    Topics: Autoradiography; Cell Division; Cell Nucleolus; Cell Nucleus; Colchicine; DNA; Glioma; Humans; In Vi

1967
Cell cycle-specific changes in beta-adrenergic receptor concentrations in C6 glioma cells.
    Biochemical and biophysical research communications, 1980, Jun-30, Volume: 94, Issue:4

    Topics: Animals; Cell Cycle; Cell Line; DNA, Neoplasm; Glioma; Kinetics; Mitosis; Pindolol; Rats; Receptors,

1980
Methodological aspects of microelectrode measurements in cellular spheroids.
    Advances in experimental medicine and biology, 1983, Volume: 159

    Topics: Animals; Autoradiography; Cell Aggregation; Cells, Cultured; Cricetinae; Culture Media; Glioma; Huma

1983
Interferon effects on multiplication, cytoplasmic protein and GFAP content, and morphology in human glioma cells.
    Journal of neuro-oncology, 1983, Volume: 1, Issue:1

    Topics: Cell Division; Cell Line; DNA, Neoplasm; Glial Fibrillary Acidic Protein; Glioma; Humans; Interferon

1983
Cytotoxic effects of alkyl-lysophospholipids in human brain tumor cells.
    Oncology, 1984, Volume: 41, Issue:2

    Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cell Survival; Cells, Cultured; Glioma; Histocy

1984
Regional thymidine transport and incorporation in experimental brain and subcutaneous tumors.
    Journal of neurochemistry, 1984, Volume: 43, Issue:2

    Topics: Animals; Biological Transport; Brain; Brain Neoplasms; Carbon Radioisotopes; DNA Replication; Glioma

1984
Vitamin B6 kills hepatoma cells in culture.
    Nutrition and cancer, 1982, Volume: 3, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Count; Cell Division;

1982
Membrane potential and sodium flux in neuroblastoma X glioma hybrid cells: effects of amiloride and serum.
    Journal of cellular physiology, 1982, Volume: 113, Issue:3

    Topics: Amiloride; Animals; Blood; Cell Line; Dose-Response Relationship, Drug; Glioma; Hybrid Cells; Membra

1982
Penetration of substances into tumor tissue--a methodological study on cellular spheroids.
    In vitro, 1981, Volume: 17, Issue:4

    Topics: Albumins; Biological Transport; Cell Line; Clone Cells; Fluorouracil; Glioma; Humans; Leucine; Model

1981
Effect of tritiated thymidine on the kinetics and viability of 9L cells in vitro.
    Cell and tissue kinetics, 1981, Volume: 14, Issue:5

    Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cell Survival; Colony-Forming Units Assay; Gliom

1981
Stimulation of DNA synthesis and pyrimidine deoxyribonucleoside transport systems in mouse glioma and mouse neuroblastoma cells by inorganic mercury.
    Toxicology and applied pharmacology, 1980, Mar-30, Volume: 53, Issue:1

    Topics: Animals; Cells, Cultured; Deoxyribonucleosides; DNA; Glioma; Mercury; Mice; Neoplasms, Experimental;

1980
Gangliosides have a bimodal effect on DNA synthesis in U-1242 MG human glioma cells.
    Journal of neuroscience research, 1995, Jul-01, Volume: 41, Issue:4

    Topics: Cell Line; DNA Replication; Dose-Response Relationship, Drug; Gangliosides; Glioma; Humans; Kinetics

1995
Apoptosis of human glioma cells in response to calphostin C, a specific protein kinase C inhibitor.
    Journal of neurosurgery, 1995, Volume: 83, Issue:6

    Topics: Alkaloids; Antibiotics, Antineoplastic; Apoptosis; Autoradiography; Blotting, Northern; Blotting, We

1995
Alterations in the synthesis of insulin-like growth factor binding proteins and insulin-like growth factors in rat C6 glioma cells transfected with a gap junction connexin43 cDNA.
    Regulatory peptides, 1993, Oct-20, Volume: 48, Issue:1-2

    Topics: Animals; Animals, Newborn; Astrocytes; Blotting, Northern; Carrier Proteins; Cell Division; Cell Lin

1993
Effect of cocaine on macromolecular syntheses and cell proliferation in cultured glial cells.
    Neuroscience, 1993, Volume: 57, Issue:2

    Topics: Animals; Animals, Newborn; Brain Neoplasms; Cell Division; Cells, Cultured; Cocaine; DNA; Glioma; Gl

1993
Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells.
    Cancer gene therapy, 1994, Volume: 1, Issue:2

    Topics: Acyclovir; Adenoviruses, Human; Animals; Arabinonucleosides; Avian Sarcoma Viruses; Brain Neoplasms;

1994
Modulation of metallothionein-III mRNA content and growth rate of rat C6-glial cells by transfection with human 5-HT1D receptor genes.
    Biochemical and biophysical research communications, 1995, Sep-14, Volume: 214, Issue:2

    Topics: Actins; Animals; Animals, Newborn; Astrocytes; Base Sequence; Brain; Cell Line; Cells, Cultured; DNA

1995
Role of calmodulin-dependent phosphorylation of elongation factor 2 in the proliferation of rat glial cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1994, Volume: 5, Issue:12

    Topics: Animals; Animals, Newborn; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Calmodulin; Cell D

1994
Opioids inhibit endothelin-mediated DNA synthesis, phosphoinositide turnover, and Ca2+ mobilization in rat C6 glioma cells.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1994, Volume: 14, Issue:10

    Topics: Animals; Antibodies, Anti-Idiotypic; beta-Endorphin; Calcium; Desipramine; DNA, Neoplasm; Dose-Respo

1994
Functional coupling of the human dopamine D3 receptor in a transfected NG 108-15 neuroblastoma-glioma hybrid cell line.
    European journal of pharmacology, 1994, Jul-15, Volume: 268, Issue:2

    Topics: Animals; Cyclic AMP; Ergolines; Genes, fos; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotrip

1994
A comparison of the relative chemosensitivity of human gliomas to tamoxifen and n-desmethyltamoxifen in vitro.
    Journal of neuro-oncology, 1994, Volume: 19, Issue:2

    Topics: Colorimetry; Coloring Agents; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gl

1994
Cytotoxicity of the cocaine metabolite benzoylecgonine.
    Brain research, 1994, Apr-18, Volume: 643, Issue:1-2

    Topics: Animals; Cell Death; Cell Division; Cell Survival; Cocaine; DNA, Neoplasm; Glioma; Hybrid Cells; Mic

1994
Human osteosarcoma (U-2 OS) cells express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptors and synthesize IGF-II: autocrine growth stimulation by IGF-II via the IGF-I receptor
    Journal of cellular physiology, 1994, Volume: 159, Issue:3

    Topics: Animals; Binding, Competitive; Blood; Blotting, Northern; Blotting, Western; Bone Neoplasms; Cell Di

1994
Selective induction of alpha 1 isoform of (Na+ + K+)-ATPase by insulin/insulin-like growth factor-I in cultured rat astrocytes.
    Archives of biochemistry and biophysics, 1993, Nov-15, Volume: 307, Issue:1

    Topics: Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Ca(2+) Mg(2+)-ATPase; Cell Division; Cells

1993
A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA.
    Glia, 1994, Volume: 10, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Division; Cell Membrane; Colorimetry; Densito

1994
Responses of human glioblastoma cells to human natural tumor necrosis factor-alpha: susceptibility, mechanism of resistance and cytokine production studies.
    Journal of neuro-oncology, 1993, Volume: 15, Issue:3

    Topics: Cell Division; Colony-Forming Units Assay; Coloring Agents; Cytokines; Dinoprostone; Drug Resistance

1993
Preliminary observations on the in vitro toxicity of N-butylbenzenesulfonamide: a newly discovered neurotoxin.
    Annals of the New York Academy of Sciences, 1993, May-28, Volume: 679

    Topics: Animals; Biomarkers; Cell Death; Cell Division; Cell Line; DNA Replication; Glioma; Kinetics; L-Lact

1993
Antiproliferative effect of multiple autocrine loop blockade in human malignant glioma cell lines.
    Neurologia medico-chirurgica, 1995, Volume: 35, Issue:10

    Topics: Antibodies, Monoclonal; Cell Movement; Cells, Cultured; Fibroblast Growth Factor 2; Glioma; Glucose-

1995
CCKB receptor activation results in increased [3H]thymidine incorporation in rat glioma C6 cells.
    Neuropeptides, 1995, Volume: 29, Issue:5

    Topics: Amino Acid Sequence; Animals; Benzodiazepinones; Cell Division; Cholecystokinin; Devazepide; DNA; Gl

1995
Inhibition of the proliferation of human neural neoplastic cell lines by cysteamine.
    Cancer letters, 1996, May-15, Volume: 103, Issue:1

    Topics: Blood-Brain Barrier; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line; Cysteamine; DNA, Neoplas

1996
Altered phospholipid metabolism in sodium butyrate-induced differentiation of C6 glioma cells.
    Lipids, 1997, Volume: 32, Issue:3

    Topics: Acylation; Animals; Arachidonic Acid; Butyrates; Butyric Acid; Calcium; Chloroform; Glioma; Glutamat

1997
Modulation of motility and proliferation of glioma cells by hepatocyte growth factor.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Aged; Base Sequence; Brain Neoplasms; Cell Division; Cell Movement; DNA Primers;

1997
Quantitative study of calcium uptake by tumorigenic bone (TE-85) and neuroblastoma x glioma (NG108-15) cells exposed to extremely-low-frequency (ELF) electric fields.
    FEBS letters, 1997, Sep-08, Volume: 414, Issue:2

    Topics: Animals; Biological Transport; Bone Neoplasms; Calcium; Cattle; Cell Division; DNA, Neoplasm; Electr

1997
Opioid receptor and calcium channel regulation of adenylyl cyclase, modulated by GM1, in NG108-15 cells: competitive interactions.
    Neurochemical research, 1997, Volume: 22, Issue:10

    Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Aminopterin; Binding, Competitive; Calcium Channels; Cho

1997
In vitro efficacy of anti-glial fibrillary acidic protein monoclonal antibodies against human malignant glioma cell lines.
    Japanese journal of cancer research : Gann, 1997, Volume: 88, Issue:11

    Topics: Antibodies, Monoclonal; Cell Division; Cell Survival; Glial Fibrillary Acidic Protein; Glioma; Human

1997
Improved method to prepare RNA-free DNA from mammalian cells.
    Journal of chromatography. B, Biomedical sciences and applications, 1997, Nov-21, Volume: 702, Issue:1-2

    Topics: Animals; Chromatography, High Pressure Liquid; DNA, Neoplasm; Glioma; Osmolar Concentration; Rats; R

1997
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells.
    Journal of neurochemistry, 1998, Volume: 70, Issue:6

    Topics: Animals; Cell Division; Diterpenes; Electrophoresis, Polyacrylamide Gel; Farnesol; Glioma; Hydroxyme

1998
Serum mitogenic activity on in vitro glial cells in Neurofibromatosis type 1.
    Brain research, 1998, May-18, Volume: 793, Issue:1-2

    Topics: Animals; Dose-Response Relationship, Drug; Glioma; Humans; Lymphocytes; Mitogens; Mitosis; Molecular

1998
Protein kinase C is involved in cholecystokinin octapeptide-induced proliferative action in rat glioma C6 cells.
    Neuropeptides, 1998, Volume: 32, Issue:2

    Topics: Animals; Blotting, Western; Carcinogens; Enzyme Activation; Glioma; Isoenzymes; Protein Kinase C; Pr

1998
Epidermal growth factor receptor and labeling index are independent prognostic factors in glial tumor outcome.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:10

    Topics: Adolescent; Adult; Aged; Cell Division; ErbB Receptors; Female; Glioma; Humans; Male; Middle Aged; M

1998
Light-induced photoactivation of hypericin affects the energy metabolism of human glioma cells by inhibiting hexokinase bound to mitochondria.
    Cancer research, 1998, Dec-15, Volume: 58, Issue:24

    Topics: Anthracenes; Apoptosis; Energy Metabolism; Enzyme Inhibitors; Glioma; Hexokinase; Humans; Hydrogen-I

1998
Cell surface aggregation of elastin receptor molecules caused by suramin amplified signals leading to proliferation of human glioma cells.
    Acta neuropathologica, 1999, Volume: 97, Issue:4

    Topics: Cell Division; Culture Media, Serum-Free; Cyclin-Dependent Kinases; Cyclins; Dose-Response Relations

1999
Control of proliferation and survival of C6 glioma cells with modification of the nerve growth factor autocrine system.
    Journal of neuro-oncology, 1999, Volume: 41, Issue:2

    Topics: Animals; Autocrine Communication; Cell Count; Cell Division; Cell Survival; Cycloheximide; Glioma; N

1999
A globin fragment, LVV-hemorphin-7, induces [3H]thymidine incorporation in a neuronal cell line via the AT4 receptor.
    Journal of neurochemistry, 1999, Volume: 73, Issue:1

    Topics: Angiotensin II; Binding, Competitive; DNA; Glioma; Hemoglobins; Hybrid Cells; Losartan; Neuroblastom

1999
Interferon gamma inhibits proliferation and hyaluronic acid adhesion of human malignant glioma cells in vitro.
    Cytokine, 2000, Volume: 12, Issue:4

    Topics: Cell Adhesion; Cell Division; Cell Survival; Glioma; Humans; Hyaluronan Receptors; Hyaluronic Acid;

2000
Alterations in Ca2+ signaling, and c-fos and nur77 expression are associated with sodium butyrate-induced differentiation of C6 glioma cell.
    The Chinese journal of physiology, 2000, Dec-31, Volume: 43, Issue:4

    Topics: Adenosine Triphosphate; Animals; Butyrates; Calcium; Calcium Signaling; Cell Differentiation; Chelat

2000
Monoclonal anti-GD3 antibodies selectively inhibit the proliferation of human malignant glioma cells in vitro.
    Glycoconjugate journal, 2000, Volume: 17, Issue:10

    Topics: Antibodies, Monoclonal; Cell Division; Central Nervous System Neoplasms; Drug Screening Assays, Anti

2000
Growth hormone and insulin-like growth factor-I: effects on the growth of glioma cell lines.
    Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, 2001, Volume: 11, Issue:2

    Topics: Animals; Cell Division; Central Nervous System Neoplasms; DNA; Female; Gene Expression Regulation, N

2001
Effects of extracellular Ca2+ influx on endothelin-1-induced intracellular mitogenic cascades in C6 glioma cells.
    European journal of pharmacology, 2002, Jan-25, Volume: 435, Issue:2-3

    Topics: Acetamides; Animals; Brain Neoplasms; Calcium; Calcium Channel Blockers; Calcium Channels; DNA; Drug

2002
Double-stranded ribonucleic acid decreases c6 rat glioma cell proliferation in part by activating protein kinase R and decreasing insulin-like growth factor I levels.
    Endocrinology, 2002, Volume: 143, Issue:6

    Topics: Animals; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line; Coloring Agents;

2002
Cyclic AMP, membrane transport and cell division. I. Effects of various chemicals on cyclic AMP levels and rate of transport of neucleosides, hypoxanthine and deoxyglucose in several lines of cultured cells.
    Journal of cellular physiology, 1975, Volume: 85, Issue:2 Pt 1

    Topics: Animals; Biological Transport, Active; Bucladesine; Carcinoma, Hepatocellular; Cell Division; Cell L

1975
Gemistocytic astrocytes in gliomas. An autoradiographic study.
    Journal of neuropathology and experimental neurology, 1975, Volume: 34, Issue:3

    Topics: Adolescent; Adult; Aged; Astrocytes; Astrocytoma; Autoradiography; Brain Neoplasms; Frontal Lobe; Gl

1975
Morphological differentiation of cultured mouse glioblastoma cells induced by dibutyryl cyclic adenosine monophosphate.
    Cancer research, 1975, Volume: 35, Issue:9

    Topics: Animals; Bucladesine; Butyrates; Cell Differentiation; Cell Line; Cells, Cultured; Cyclic GMP; DNA,

1975
Effect of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride on experimental brain tumors.
    Cancer research, 1979, Volume: 39, Issue:7 Pt 1

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Drug Evaluation, Preclinical; Ependymoma

1979
The stathmokinetic (mitostatic) effect of vincristine and vinblastine on human gliomas.
    Acta neuropathologica, 1979, Jun-15, Volume: 47, Issue:1

    Topics: Adult; Aged; Biopsy; Brain; Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Mitotic Inde

1979
[Kinetics of neutrophil granulocytes in man].
    Verhandlungen der Anatomischen Gesellschaft, 1978, Issue:72

    Topics: Basophils; Cell Survival; Glioma; Humans; Leukemia, Lymphoid; Neutrophils; Thymidine

1978
The inhibition of thymidine metabolism in tumor cells treated with D-glucosamine.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: Cell Line; DNA, Neoplasm; Glioma; Glucosamine; Kinetics; Neoplasms, Experimental; Thymidine

1977
Effects of bacterial agarase on agarose gel in cell culture.
    In vitro, 1977, Volume: 13, Issue:7

    Topics: Bacteria; Cell Line; Cells, Cultured; Culture Media; DNA, Neoplasm; Glioma; Glycoside Hydrolases; Hu

1977
Environmental factors in glial tumor response to 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea: effect of cell confluence.
    Journal of the National Cancer Institute, 1977, Volume: 59, Issue:5

    Topics: Cell Cycle; Cell Survival; Cells, Cultured; DNA, Neoplasm; Glioma; Lomustine; Neoplasms, Experimenta

1977
Chemotherapeutic implications of growth fraction and cell cycle time in glioblastomas.
    Journal of neurosurgery, 1975, Volume: 43, Issue:2

    Topics: Biopsy; Cell Division; Cerebral Ventricle Neoplasms; Cerebral Ventricles; Glioma; Humans; Mitosis; M

1975
Tumor growth regulation by modulation of basic fibroblast growth factor.
    EXS, 1992, Volume: 61

    Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Cell Line; DNA Replication; Fibroblast Growth Fa

1992
Activation of phospholipase D by platelet-derived growth factor (PDGF) in rat C6 glioma cells: possible role in mitogenic signal transduction.
    Neurological research, 1992, Volume: 14, Issue:5

    Topics: Animals; Choline; DNA Replication; DNA, Neoplasm; Enzyme Activation; Glioma; Glycerophospholipids; K

1992
Murine monoclonal antibodies cytotoxic to human glioma cells in vitro.
    Histology and histopathology, 1992, Volume: 7, Issue:4

    Topics: Adult; Animals; Antibodies, Monoclonal; Astrocytes; Cytotoxicity Tests, Immunologic; Glioma; Humans;

1992
Metabolic changes of glioma following chemotherapy: an experimental study using four PET tracers.
    Journal of neuro-oncology, 1992, Volume: 14, Issue:1

    Topics: Animals; Body Weight; Carbon Radioisotopes; Deoxyglucose; DNA Replication; DNA, Neoplasm; Dose-Respo

1992
Contribution of labeled carbon dioxide to PET imaging of carbon-11-labeled compounds.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1992, Volume: 33, Issue:4

    Topics: Acetates; Animals; Brain Neoplasms; Carbon Dioxide; Carbon Radioisotopes; Dogs; Glioma; Glucose; Hum

1992
Regulation of insulin-like growth factor I production in rat C6 glioma cells: possible role as an autocrine/paracrine growth factor.
    Endocrinology, 1992, Volume: 130, Issue:5

    Topics: Animals; Blotting, Northern; Cell Division; Cell Line; Cycloheximide; Dexamethasone; DNA Replication

1992
Effects of RF power absorption in mammalian cells.
    Annals of the New York Academy of Sciences, 1992, Mar-31, Volume: 649

    Topics: Animals; Cell Division; Cell Line; Cell Membrane Permeability; DNA Replication; Energy Metabolism; E

1992
[The effect of the synthetic leu-enkephalin analog dalargin on the proliferative activity of glioma C6 cells and on the intensity of their DNA synthesis].
    Tsitologiia, 1992, Volume: 34, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; DNA, Neoplasm; Drug Interactions; Enkephalin, Le

1992
Sertoli cells in culture secrete paracrine factor(s) that inhibit peritubular myoid cell proliferation: identification of heparinoids as likely candidates.
    Journal of cellular physiology, 1991, Volume: 147, Issue:3

    Topics: Animals; Cell Division; Cell Line; DNA; Glioma; Glycosaminoglycans; Growth Inhibitors; Heparin; Hepa

1991
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine.
    Cancer research, 1992, Feb-01, Volume: 52, Issue:3

    Topics: Animals; Cell Line; Combined Modality Therapy; DNA, Neoplasm; Flow Cytometry; Glioma; Head and Neck

1992
Transient heat shock in mid-G1-phase of the C6 glioma cell cycle impairs entry into S-phase.
    Toxicology letters, 1991, Volume: 59, Issue:1-3

    Topics: Animals; Cell Line; DNA; G1 Phase; Glioma; Hot Temperature; Rats; S Phase; Thymidine

1991
Bispecific antibody-directed antitumor activity of human CD4+ helper/killer T cells induced by anti-CD3 monoclonal antibody plus interleukin 2.
    Japanese journal of cancer research : Gann, 1991, Volume: 82, Issue:11

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcimycin; CD3 Compl

1991
Effects of the PAF-analog and -antagonist CV-6209 on cultured human glioma cell lines.
    Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 43, Issue:2

    Topics: Cell Division; Cell Line; Cell Survival; DNA Replication; Glioma; Humans; Kinetics; Methionine; Neur

1991
The anticonvulsant valproate teratogen restricts the glial cell cycle at a defined point in the mid-G1 phase.
    Brain research, 1991, Jul-19, Volume: 554, Issue:1-2

    Topics: Animals; Cell Cycle; Cell Division; Cell Line; Cell Survival; DNA Replication; G1 Phase; Glioma; Kin

1991
Transcriptional regulation of ferritin messenger ribonucleic acid levels by insulin in cultured rat glioma cells.
    Endocrinology, 1991, Volume: 128, Issue:3

    Topics: Actins; Animals; Cycloheximide; Dactinomycin; Drug Stability; Ferritins; Glioma; Insulin; Insulin-Li

1991
Diacylglycerol formation and DNA synthesis in endothelin-stimulated rat C6 glioma cells: the possible role of phosphatidylcholine breakdown.
    Neuroscience letters, 1991, Feb-25, Volume: 123, Issue:2

    Topics: Animals; Diglycerides; DNA; Endothelins; Glioma; Phosphatidylcholines; Thymidine; Tumor Cells, Cultu

1991
Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:16

    Topics: Blotting, Northern; Blotting, Southern; Cell Cycle; Cell Division; Cell Line; Dexamethasone; DNA Rep

1990
Stimulation of cell growth and DNA synthesis by peripheral benzodiazepine.
    Cancer letters, 1990, Volume: 49, Issue:2

    Topics: Animals; Benzodiazepines; Benzodiazepinones; Cell Division; Cell Line; DNA Replication; DNA, Neoplas

1990
Response of malignant glioma cell lines to activation and inhibition of protein kinase C-mediated pathways.
    Journal of neurosurgery, 1990, Volume: 73, Issue:1

    Topics: Animals; Brain; Brain Neoplasms; Cell Division; DNA, Neoplasm; Epidermal Growth Factor; Glioma; Huma

1990
Insulin-like growth factor-I receptors in human glial tumors.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:1

    Topics: Binding, Competitive; Brain Neoplasms; Cell Membrane; Chromatography, Affinity; DNA, Neoplasm; Gliom

1990
Sensitization of C6 glioma to carboplatin cytotoxicity by hyperthermia and thymidine.
    Journal of neuro-oncology, 1990, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Carboplatin; Cell Survival; Combined Modality Therapy; Dose-Response

1990
Effects of trifluoroacetic acid, a halothane metabolite, on C6 glioma cells.
    Journal of toxicology and environmental health, 1990, Volume: 31, Issue:2

    Topics: Animals; Cell Division; DNA, Neoplasm; Glioma; Glycoproteins; Glycosylation; Leucine; Mannose; Mice;

1990
Radiosensitization of C6 glioma by thymidine and 41.8 degrees C hyperthermia.
    Journal of neurosurgery, 1990, Volume: 72, Issue:5

    Topics: Animals; Cell Line; Glioma; Hyperthermia, Induced; Radiation Dosage; Radiation Tolerance; Radiation-

1990
Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium.
    Journal of neurosurgery, 1990, Volume: 73, Issue:1

    Topics: Brain Neoplasms; Cell Division; Culture Media; Epidermal Growth Factor; Glioma; Humans; Iodine Radio

1990
Effect of phorbol esters on the susceptibility of a glioma cell line to lymphokine-activated killer cell activity.
    Journal of neurosurgery, 1990, Volume: 73, Issue:1

    Topics: Cell Division; Glioma; Humans; Killer Cells, Lymphokine-Activated; Phorbol 12,13-Dibutyrate; Phorbol

1990
Cell kinetics of intracerebrally implanted RG-C6 tumors in rats--effects of intracarotid hyperosmolar mannitol measured by 3H-thymidine autoradiography and bromodeoxyuridine uptake.
    Neurologia medico-chirurgica, 1988, Volume: 28, Issue:6

    Topics: Animals; Autoradiography; Brain Neoplasms; Bromodeoxyuridine; Carotid Artery, Internal; Cell Cycle;

1988
Cell kinetic investigations in brain tumors studied by serial stereotactic biopsy.
    Journal of neuro-oncology, 1989, Volume: 7, Issue:4

    Topics: Adolescent; Adult; Astrocytoma; Biopsy; Brain Neoplasms; Cell Division; Child; Child, Preschool; Fem

1989
Inhibitory effect of calcium channel blockers on proliferation of human glioma cells in vitro.
    Acta neurologica Scandinavica, 1989, Volume: 79, Issue:2

    Topics: Calcium; Calcium Channel Blockers; Cell Division; Glioma; Humans; Nimodipine; Thymidine; Tumor Cells

1989
The effects of human recombinant tumor necrosis factor on glioma-derived cell lines: cellular proliferation, cytotoxicity, morphological and radioreceptor studies.
    International journal of cancer, 1988, Apr-15, Volume: 41, Issue:4

    Topics: Cell Division; Cell Survival; Glioma; Humans; Radioligand Assay; Receptors, Cell Surface; Receptors,

1988
Stimulation of glucose analogue uptake by cerebral microvessel endothelial cells by a product released by astrocytes.
    Journal of neuropathology and experimental neurology, 1989, Volume: 48, Issue:1

    Topics: 3-O-Methylglucose; Animals; Astrocytes; Blood-Brain Barrier; Brain; Cells, Cultured; Culture Media;

1989
Brain damage by AIDS under active study.
    Science (New York, N.Y.), 1987, Mar-27, Volume: 235, Issue:4796

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Cell

1987
Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro.
    Acta neurologica Scandinavica, 1988, Volume: 77, Issue:3

    Topics: Astrocytoma; Benzodiazepines; Benzodiazepinones; Cell Division; Clonazepam; Diazepam; Female; Flumaz

1988
[Effects of cytokines on cultured microvascular endothelial cells derived from gerbil brain].
    No to shinkei = Brain and nerve, 1988, Volume: 40, Issue:12

    Topics: Animals; Brain; Cells, Cultured; DNA; Endothelium, Vascular; Gerbillinae; Glioma; Humans; Interferon

1988
Prostaglandins: antiproliferative effect of PGD 2 on cultured human glioma cells.
    Acta neurochirurgica, 1986, Volume: 83, Issue:1-2

    Topics: Cell Division; Cell Line; Dinoprost; Dinoprostone; Glioma; Humans; Prostaglandin D2; Prostaglandins

1986
Cell kinetics of gliomas by serial stereotactic biopsy.
    Basic and applied histochemistry, 1986, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Cell Cycle; Cell Division; Child; Female; Glioma; Humans; Magnetic Resonance Spec

1986
Uridine enhances the cytotoxic effect of D-glucosamine in rat C6 glioma cells.
    Life sciences, 1986, Dec-08, Volume: 39, Issue:23

    Topics: Animals; Cell Line; Cell Survival; Drug Synergism; Glioma; Glucosamine; Mannose; Rats; Thymidine; Ur

1986
Therapeutic levels of sodium valproate inhibit mitotic indices in cells of neural origin.
    Brain research, 1985, Nov-18, Volume: 347, Issue:2

    Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Glioma; M

1985
Cellular pharmacology of doxorubicin in sensitive and resistant rat glioblastoma cells in culture.
    Oncology, 1986, Volume: 43, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Count; Cell Division; Cells, Cultured; Doxorubicin; Drug Resistance;

1986
Stem cell studies of human malignant brain tumors. Part 2: Proliferation kinetics of brain-tumor cells in vitro in early-passage cultures.
    Journal of neurosurgery, 1985, Volume: 63, Issue:3

    Topics: Brain Neoplasms; Cell Division; Cells, Cultured; Glioma; Humans; Kinetics; Thymidine

1985
Two-dimensional diffusion limited system for cell growth.
    Cell and tissue kinetics, 1985, Volume: 18, Issue:6

    Topics: Animals; Cell Division; Cell Line; Culture Techniques; Diffusion; DNA Replication; Flow Cytometry; G

1985
The deficient density-dependent growth control of human malignant glioma cells and virus-transformed glia-like cells in culture.
    International journal of cancer, 1973, Sep-15, Volume: 12, Issue:2

    Topics: Autoradiography; Cell Count; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplasti

1973
Screening of carcinostatic agents in organ culture.
    Gan, 1968, Volume: 59, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Carcinoma; Cerebellar Neoplasms; Chickens; Culture Techniques;

1968
[3H-thymidin-autoradiography of experimentally produced tumors of the nervous system of the rat].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1968, Volume: 52

    Topics: Animals; Autoradiography; Brain Neoplasms; DNA, Neoplasm; Glioma; Neoplasms, Experimental; Neoplasms

1968
Radiosensitization of brain tumor cells with a thymidine analogue (bromouridine).
    Journal of neurosurgery, 1968, Volume: 28, Issue:6

    Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Culture Techniques; DNA; Floxuridine; Fluorouracil;

1968
Prolonged carotid arterial radiosensitizer infusion and radiation therapy of mouse gliomas.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1972, Volume: 114, Issue:1

    Topics: Animals; Brain Neoplasms; Bromine; Carotid Arteries; Catheterization; Craniotomy; Cytidine; Deoxyrib

1972
[Proliferative activity of neuroglial tumors].
    Tsitologiia, 1970, Volume: 12, Issue:4

    Topics: Adult; Animals; Astrocytoma; Autoradiography; Brain Neoplasms; Child, Preschool; Ependymoma; Female;

1970
Cell kinetics of human gliomas.
    Journal of neurosurgery, 1972, Volume: 37, Issue:1

    Topics: Astrocytoma; Autoradiography; Brain; Brain Neoplasms; Carbon Isotopes; DNA; Glioblastoma; Glioma; Hu

1972
Tissue culture studies of children's tumours.
    The Journal of pathology, 1973, Volume: 111, Issue:2

    Topics: Autoradiography; Child; Culture Media; Culture Techniques; Cytotoxicity Tests, Immunologic; Freezing

1973
[Cyclic AMP and malignant glioma. II. Effects of cyclic AMP on the growth of glial tumors].
    Rinsho shinkeigaku = Clinical neurology, 1973, Volume: 13, Issue:11

    Topics: Animals; Cell Division; Cells, Cultured; Cyclic AMP; Glioma; HeLa Cells; Rats; Thymidine; Tritium

1973
Sodium uptake associated with activation of action potential ionophores of cultured neuroblastoma and muscle cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1973, Volume: 70, Issue:12

    Topics: Action Potentials; Animals; Biological Transport; Cell Membrane Permeability; Clone Cells; Glioma; H

1973
Effect of corticosteroid on protein and nucleic acid synthesis in human glial tumor cells.
    Cancer research, 1973, Volume: 33, Issue:7

    Topics: Brain Neoplasms; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Humans; In Vitr

1973
[Blood brain barrier for thymidine in experimentally produced tumors of the central nervous system of the rat].
    Virchows Archiv. B, Cell pathology, 1971, Volume: 7, Issue:2

    Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain Neoplasms; DNA, Neoplasm; Glioma; Neoplasms, Ex

1971
Tumors of the nervous system induced by ethylnitrosourea administered either intracerebrally of subcutaneously to newborn rats. Morphological and biochemical characteristics.
    Journal of neurosurgery, 1972, Volume: 37, Issue:5

    Topics: Animals; Brain; Brain Neoplasms; Desmosterol; DNA; DNA, Neoplasm; Ependymoma; Female; Glioma; Neuril

1972
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
    Cancer research, 1972, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Iso

1972
Kinetics of gliomas in rat and man.
    Progress in experimental tumor research, 1972, Volume: 17

    Topics: Animals; Autoradiography; Brain Neoplasms; Carbon Isotopes; DNA, Neoplasm; Glioma; Humans; Kinetics;

1972
[Radioautographic study of cell proliferation in rat primary gliomas induced by 9,10-dimethyl-1,2-benzanthracene].
    Tsitologiia, 1971, Volume: 13, Issue:7

    Topics: Animals; Autoradiography; Benz(a)Anthracenes; Cell Division; Cerebellar Neoplasms; Cerebellum; Gliom

1971
Growth behaviour of human brain tumours in matrix cultures in fresh autologous serum.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1970, Volume: 78, Issue:3

    Topics: Autoradiography; Blood; Brain Neoplasms; Culture Media; Fibrin Foam; Glioma; Growth; Humans; Meningi

1970