thymidine has been researched along with Genetic Predisposition in 19 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to investigate a possible association among the thermolabile polymorphism, nucleotide 677 cytosine to thymidine point mutation (677 C-->T) of the methylenetetrahydrofolate reductase (MTHFR) gene, hyperhomocysteinemia, serum folate, vitamins B12 and B6, and stroke in children." | 3.70 | Children with stroke: polymorphism of the MTHFR gene, mild hyperhomocysteinemia, and vitamin status. ( Artuch, R; Campistol, J; Cardo, E; Colomé, C; Monrós, E; Pineda, M; Vilaseca, MA, 2000) |
| "A total of 380 patients with chronic periodontitis and 590 unrelated healthy control individuals of Caucasian descent were genotyped for the GT repeat microsatellite polymorphism of the TLR2 gene." | 1.37 | Microsatellite GT polymorphism in intron 2 of human Toll-like receptor (TLR) 2 gene and susceptibility to periodontitis. ( Folwaczny, M; Glas, J; Tonenchi, L; Török, HP, 2011) |
| "Furthermore, breast cancer risks associated with the TS3'-UTR del6/del6 genotype were more evident in older women, postmenopausal subjects, individuals with a younger age at first-live birth and individuals with an older age at menarche." | 1.33 | Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis. ( Chen, F; Chen, W; Gao, J; Hu, Z; Jin, G; Liu, J; Qin, J; Shen, H; Tang, J; Wang, S; Wang, X; Wei, Q; Zhai, X, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (78.95) | 29.6817 |
| 2010's | 4 (21.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Emingil, G | 1 |
| Han, B | 1 |
| Gürkan, A | 1 |
| Berdeli, A | 1 |
| Tervahartiala, T | 1 |
| Salo, T | 1 |
| Pussinen, PJ | 1 |
| Köse, T | 1 |
| Atilla, G | 1 |
| Sorsa, T | 1 |
| Herrera, VL | 1 |
| Pasion, KA | 1 |
| Moran, AM | 1 |
| Zaninello, R | 1 |
| Ortu, MF | 1 |
| Fresu, G | 1 |
| Piras, DA | 1 |
| Argiolas, G | 1 |
| Troffa, C | 1 |
| Glorioso, V | 1 |
| Masala, W | 1 |
| Glorioso, N | 1 |
| Ruiz-Opazo, N | 1 |
| Moran, NF | 1 |
| Bain, MD | 1 |
| Muqit, MM | 1 |
| Bax, BE | 1 |
| Oyugi, JO | 1 |
| Vouriot, FC | 1 |
| Alimonti, J | 1 |
| Wayne, S | 1 |
| Luo, M | 1 |
| Land, AM | 1 |
| Ao, Z | 1 |
| Yao, X | 1 |
| Sekaly, RP | 1 |
| Elliott, LJ | 1 |
| Simonsen, JN | 1 |
| Ball, TB | 1 |
| Jaoko, W | 1 |
| Kimani, J | 1 |
| Plummer, FA | 1 |
| Fowke, KR | 1 |
| Sfar, I | 1 |
| Gorgi, Y | 1 |
| Aouadi, H | 1 |
| Maklouf, M | 1 |
| Ben Romdhane, T | 1 |
| Jendoubi-Ayed, S | 1 |
| Bardi, R | 1 |
| Abderrahim, E | 1 |
| Ben Abdallah, T | 1 |
| Ayed, K | 1 |
| Gluck, I | 1 |
| Simon, AJ | 1 |
| Catane, R | 1 |
| Pfeffer, R | 1 |
| Schachter, J | 1 |
| Rechavi, G | 1 |
| Bar, J | 1 |
| Singh, H | 1 |
| Jain, M | 1 |
| Mittal, B | 1 |
| Folwaczny, M | 1 |
| Glas, J | 1 |
| Tonenchi, L | 1 |
| Török, HP | 1 |
| Kemmerich, K | 1 |
| Dingler, FA | 1 |
| Rada, C | 1 |
| Neuberger, MS | 1 |
| Wallström, P | 1 |
| Frenkel, K | 1 |
| Wirfält, E | 1 |
| Gullberg, B | 1 |
| Karkoszka, J | 1 |
| Seidegård, J | 1 |
| Janzon, L | 1 |
| Berglund, G | 1 |
| Falcone, C | 2 |
| Campo, I | 2 |
| Emanuele, E | 2 |
| Buzzi, MP | 2 |
| Zorzetto, M | 2 |
| Sbarsi, I | 2 |
| Cuccia, M | 2 |
| Geroldi, D | 1 |
| Belvito, C | 1 |
| Deng, Y | 1 |
| Sun, Y | 1 |
| Shi, JJ | 1 |
| Zhang, SZ | 1 |
| Zhai, X | 1 |
| Gao, J | 1 |
| Hu, Z | 1 |
| Tang, J | 1 |
| Qin, J | 1 |
| Wang, S | 1 |
| Wang, X | 2 |
| Jin, G | 1 |
| Liu, J | 1 |
| Chen, W | 1 |
| Chen, F | 1 |
| Wei, Q | 2 |
| Shen, H | 1 |
| Lu, J | 1 |
| Wang, LE | 1 |
| Xiong, P | 1 |
| Sturgis, EM | 1 |
| Spitz, MR | 1 |
| Lin, CH | 1 |
| Wang, SC | 1 |
| Ou, TT | 1 |
| Li, RN | 1 |
| Tsai, WC | 1 |
| Liu, HW | 1 |
| Yen, JH | 1 |
| Cardo, E | 1 |
| Monrós, E | 1 |
| Colomé, C | 1 |
| Artuch, R | 1 |
| Campistol, J | 1 |
| Pineda, M | 1 |
| Vilaseca, MA | 1 |
| Wilson, JW | 1 |
| Potten, CS | 1 |
| Couturaud, F | 1 |
| Oger, E | 1 |
| Abalain, JH | 1 |
| Chenu, E | 1 |
| Guias, B | 1 |
| Floch, HH | 1 |
| Mercier, B | 1 |
| Mottier, D | 1 |
| Leroyer, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Safety, Tolerability, Pharmacodynamics, and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase (EE-TP) in Patients With MNGIE[NCT03866954] | Phase 2 | 0 participants (Actual) | Interventional | 2024-11-30 | Withdrawn (stopped due to Change of circumstances with Commercial partner) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
19 other studies available for thymidine and Genetic Predisposition
| Article | Year |
|---|---|
Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in generalized aggressive periodontitis: gingival crevicular fluid MMP-8 and TIMP-1 levels and outcome of periodontal therapy.
Topics: Adenine; Adolescent; Adult; Aggressive Periodontitis; Alveolar Bone Loss; Biomarkers; Cytosine; Fema | 2014 |
A functional 12T-insertion polymorphism in the ATP1A1 promoter confers decreased susceptibility to hypertension in a male Sardinian population.
Topics: Adult; Aged; Animals; Disease Models, Animal; Essential Hypertension; Genetic Predisposition to Dise | 2015 |
Carrier erythrocyte entrapped thymidine phosphorylase therapy for MNGIE.
Topics: Adult; Deoxyuridine; Drug Delivery Systems; Erythrocyte Transfusion; Erythrocytes; Fatal Outcome; Fe | 2008 |
A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers.
Topics: Acquired Immunodeficiency Syndrome; CD4 Antigens; Cytidine; DNA Primers; Female; Genetic Predisposit | 2009 |
The PTPN22 C1858T (R620W) functional polymorphism in kidney transplantation.
Topics: Adult; Amino Acid Substitution; Chromosome Mapping; Chromosomes, Human, Pair 1; Cytosine; DNA; Femal | 2009 |
Germline analysis of thymidine/guanidine polymorphism at position 309 of the Mdm2 promoter in malignant melanoma patients.
Topics: Adult; Aged; Aging; DNA; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germ C | 2009 |
Role of TGF-beta1 (-509C>T) promoter polymorphism in susceptibility to cervical cancer.
Topics: Adult; Deoxycytidine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Heterozyg | 2009 |
Microsatellite GT polymorphism in intron 2 of human Toll-like receptor (TLR) 2 gene and susceptibility to periodontitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Chi-Square Distribution; Chronic P | 2011 |
Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.
Topics: Animals; beta-Galactosidase; Cell Line; DNA Repair; Fibroblasts; Fluorouracil; Gene Targeting; Genet | 2012 |
Antibodies against 5-hydroxymethyl-2'-deoxyuridine are associated with lifestyle factors and GSTM1 genotype: a report from the Malmö Diet and Cancer cohort.
Topics: Age Distribution; Aged; Alcohol Drinking; Autoantibodies; Biomarkers; Body Composition; Cohort Studi | 2003 |
Relationship between the -374T/A RAGE gene polymorphism and angiographic coronary artery disease.
Topics: Adenosine; Alleles; Coronary Angiography; Coronary Artery Disease; Female; Genetic Predisposition to | 2004 |
-374T/A polymorphism of the RAGE gene promoter in relation to severity of coronary atherosclerosis.
Topics: Adenosine; Alleles; Coronary Artery Disease; Female; Genetic Predisposition to Disease; Genotype; Hu | 2005 |
[Meta-analysis of the association of the LRP C766T polymorphism with the risk of Alzheimer's disease].
Topics: Age of Onset; Alleles; Alzheimer Disease; Asian People; Association; Cytosine; Genetic Predispositio | 2006 |
Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Adult; Aged; Breast Neoplasms; Case-Control Studie | 2006 |
172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant.
Topics: 5' Untranslated Regions; Adolescent; Adult; Aged; Aged, 80 and over; Binding Sites; Carcinoma, Squam | 2007 |
I kappa B alpha promoter polymorphisms in patients with systemic lupus erythematosus.
Topics: Adult; Female; Genetic Predisposition to Disease; Genotype; Humans; I-kappa B Proteins; Lupus Erythe | 2008 |
Children with stroke: polymorphism of the MTHFR gene, mild hyperhomocysteinemia, and vitamin status.
Topics: Adolescent; Case-Control Studies; Child; Child, Preschool; Cytosine; Female; Folic Acid; Genetic Pre | 2000 |
The effect of exogenous prostaglandin administration on tumor size and yield in Min/+ mice.
Topics: 16,16-Dimethylprostaglandin E2; Animals; Apoptosis; Cell Cycle; Cyclin-Dependent Kinase Inhibitor p2 | 2000 |
Methylenetetrahydrofolate reductase C677T genotype and venous thromboembolic disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Case-Control Studies; Cytosine; Factor V; Female; France | 2000 |