thymidine has been researched along with Gardner Syndrome in 3 studies
Gardner Syndrome: A variant of ADENOMATOUS POLYPOSIS COLI caused by mutation in the APC gene (GENES, APC) on CHROMOSOME 5. It is characterized by not only the presence of multiple colonic polyposis but also extracolonic ADENOMATOUS POLYPS in the UPPER GASTROINTESTINAL TRACT; the EYE; the SKIN; the SKULL; and the FACIAL BONES; as well as malignancy in organs other than the GI tract.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The incidence of in vitro tetraploidy during logarithmic growth in dermal fibroblast monolayer cultures from normals without a family cancer history and affected with heritable colon cancer syndromes, familial polyposis coli (FPC) and the Gardner syndrome (GS) was assayed by (1) examination of metaphase preparations for percentage of tetraploids (4N nuclei); (2) determination of [3H]thymidine incorporation (average cpm/cell); and (3) measurement by flow cytophotometry of the percentage of cells with greater than 4C DNA content." | 3.67 | Detection of in vitro tetraploidy in heritable colon cancer syndromes. Confirmation by three different assays. ( Danes, BS; Deschner, EE, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Danes, BS | 1 |
| Deschner, EE | 1 |
| Lipkin, M | 1 |
| Blattner, WA | 1 |
| Gardner, EJ | 2 |
| Burt, RW | 1 |
| Lynch, H | 1 |
| Deschner, E | 1 |
| Winawer, S | 1 |
| Fraumeni, JF | 1 |
| Warren, RP | 1 |
| Stembridge, AM | 1 |
3 other studies available for thymidine and Gardner Syndrome
| Article | Year |
|---|---|
Detection of in vitro tetraploidy in heritable colon cancer syndromes. Confirmation by three different assays.
Topics: Cells, Cultured; Colonic Neoplasms; Colonic Polyps; DNA, Neoplasm; Flow Cytometry; Gardner Syndrome; | 1984 |
Classification and risk assessment of individuals with familial polyposis, Gardner's syndrome, and familial non-polyposis colon cancer from [3H]thymidine labeling patterns in colonic epithelial cells.
Topics: Colonic Neoplasms; Colonic Polyps; DNA Replication; Gardner Syndrome; Humans; Risk; Thymidine; Triti | 1984 |
Deficient immune function of peripheral blood mononuclear cells from patients with Gardner syndrome.
Topics: Adolescent; Adult; Child; Concanavalin A; Dose-Response Relationship, Immunologic; Female; Gardner S | 1985 |