Page last updated: 2024-11-06

thymidine and Fanconi Anemia

thymidine has been researched along with Fanconi Anemia in 7 studies

Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)

Research Excerpts

ExcerptRelevanceReference
"Uptake of 3H-thymidine and its incorporation into DNA was studied in fibroblastic cell lines derived from normal individuals, patients with Fanconi anemia, and those heterozygous for this genetic trait."7.66Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts. ( Gunnell, M; Lubiniecki, AS; Shoyab, M, 1981)
"Uptake of 3H-thymidine and its incorporation into DNA was studied in fibroblastic cell lines derived from normal individuals, patients with Fanconi anemia, and those heterozygous for this genetic trait."3.66Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts. ( Gunnell, M; Lubiniecki, AS; Shoyab, M, 1981)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Peña-Gómez, MJ1
Moreno-Gordillo, P1
Narmontė, M1
García-Calderón, CB1
Rukšėnaitė, A1
Klimašauskas, S1
Rosado, IV1
Shoyab, M1
Gunnell, M1
Lubiniecki, AS1
Vincent, RA1
Huang, PC1
Remsen, JF1
Cerutti, PA1
Elmore, E1
Swift, M1
Kenne, K1
Akerblom, L1
Poulter, L1
Adams, JA1
Knight, I1
McCarthy, DM1
Barrett, AJ1

Other Studies

7 other studies available for thymidine and Fanconi Anemia

ArticleYear
FANCD2 maintains replication fork stability during misincorporation of the DNA demethylation products 5-hydroxymethyl-2'-deoxycytidine and 5-hydroxymethyl-2'-deoxyuridine.
    Cell death & disease, 2022, 05-27, Volume: 13, Issue:5

    Topics: Deoxycytidine; DNA Demethylation; DNA Replication; Fanconi Anemia; Fanconi Anemia Complementation Gr

2022
Reduced uptake and incorporation of 3H-thymidine in Fanconi anemia fibroblasts.
    Human genetics, 1981, Volume: 57, Issue:3

    Topics: Anemia, Aplastic; Cell Line; DNA; Fanconi Anemia; Fibroblasts; Heterozygote; Humans; Thymidine

1981
The proportion of cells labeled with tritiated thymidine as a function of population doubling level in cultures of fetal, adult, mutant, and tumor origin.
    Experimental cell research, 1976, Oct-01, Volume: 102, Issue:1

    Topics: Cell Division; Cell Line; Cell Nucleus; Cells, Cultured; Fanconi Anemia; HeLa Cells; Mutation; Proge

1976
Deficiency of gamma-ray excision repair in skin fibroblasts from patients with Fanconi's anemia.
    Proceedings of the National Academy of Sciences of the United States of America, 1976, Volume: 73, Issue:7

    Topics: Anemia, Aplastic; Cell Nucleus; Cells, Cultured; DNA; DNA Repair; Fanconi Anemia; Fibroblasts; Gamma

1976
Growth of cultured cells from patients with Fanconi anemia.
    Journal of cellular physiology, 1975, Volume: 87, Issue:2

    Topics: Adolescent; Adult; Anemia, Aplastic; Cell Count; Cell Division; Cells, Cultured; Child; Child, Presc

1975
Deoxyribonucleoside triphosphate pool levels in three cell strains of human chromosome instability syndromes: ataxia telangiectasia (GM2052), Bloom's syndrome (GM1492), and Fanconi's anemia (GM368).
    Cancer biochemistry biophysics, 1990, Volume: 11, Issue:1

    Topics: Anemia, Aplastic; Ataxia Telangiectasia; Bloom Syndrome; Cell Division; Cell Line; Culture Media; De

1990
Mixed lymphocyte cultures using automated blood cell counters.
    Bone marrow transplantation, 1989, Volume: 4, Issue:6

    Topics: Anemia, Aplastic; Bone Marrow Transplantation; Fanconi Anemia; Humans; Leukemia; Leukocyte Count; Ly

1989