thymidine has been researched along with Experimental Leukemia in 232 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experiments were carried out in vitro on adriamycin (ADR) accumulation and cytotoxicity alone and in combination with calcium channel antagonist, verapamil (VRP), in ascites murine tumour models of Ehrlich carcinoma (EAC), sarcoma 180 (S180) and P388 lymphocytic leukaemia (P388)." | 7.67 | Modulation of in vitro response to adriamycin by verapamil in murine P388 leukaemia, Ehrlich ascites carcinoma and sarcoma 180. ( Basrur, VS; Chitnis, MP; Pradhan, SG; Tantri, SK, 1987) |
| "The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines." | 7.66 | Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells. ( Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B, 1980) |
| " The acid-sensitive albumin conjugates prepared with the carboxylic hydrazone doxorubicin derivatives exhibited an inhibitory efficacy in the MDA-MB-468 breast cancer cell line and U937 leukemia cell line comparable with that of the free drug (using the BrdU-(5-bromo-2'-deoxyuridine)-incorporation assay and tritiated thymidine incorporation assay respectively, IC50 approximately 0." | 3.70 | Preparation, characterization and in vitro efficacy of albumin conjugates of doxorubicin. ( Beyer, U; Cazabat, A; Collery, P; Falken, U; Kratz, F; Lechenault, F; Schumacher, P; Unger, C, 1998) |
| "Due to similarities between human immunodeficiency virus and feline leukemia virus, the etiological agents of acquired immunodeficiency syndromes in humans and cats, the feline system was used as a model to conduct preliminary investigations as to the efficacy of the thymidine analogue 3'-azido-3'-deoxythymidine (AZT) as a therapeutic and preventive agent against retroviruses." | 3.67 | 3'-Azido-3'-deoxythymidine in feline leukemia virus-infected cats: a model for therapy and prophylaxis of AIDS. ( de Noronha, F; Johnston, K; Lehrman, SN; Roneker, C; Tavares, L, 1987) |
| "Experiments were carried out in vitro on adriamycin (ADR) accumulation and cytotoxicity alone and in combination with calcium channel antagonist, verapamil (VRP), in ascites murine tumour models of Ehrlich carcinoma (EAC), sarcoma 180 (S180) and P388 lymphocytic leukaemia (P388)." | 3.67 | Modulation of in vitro response to adriamycin by verapamil in murine P388 leukaemia, Ehrlich ascites carcinoma and sarcoma 180. ( Basrur, VS; Chitnis, MP; Pradhan, SG; Tantri, SK, 1987) |
| "Both established cell lines and human leukemic cells in circulating blood which were incubated in vitro with 2'-deoxyadenosine (AdR) plus adenosine deaminase inhibitor, 2'-deoxycoformycin (dCF), showed different metabolic responses depending upon the histologic and immunologic types of leukemia." | 3.67 | Differential sensitivity of leukemic cells to growth inhibition by deoxyadenosine and deoxycoformycin. ( Kimura, K; Tanaka, M, 1985) |
| "The mouse T-lymphoma (S-49) cell line is useful for individually studying RNA- and DNA-directed effects of 5-fluoropyrimidines." | 3.66 | Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells. ( Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B, 1980) |
| "Gossypol treatments inhibited cell multiplication at 10 and 20 micrograms/ml concentrations and this inhibitory effect increased with elevated dosage and prolonged treatment." | 1.28 | Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells. ( Baker, MA; Daehler, CC; Daly, EP; Kleemeyer, KM; Majumdar, SK, 1991) |
| " All the mice given cells not treated with ALP succumbed to leukemia, whereas there was a dose-response increase in survival in those given ALP treated cells." | 1.28 | Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results. ( Berdel, WE; Glasser, L; Okamoto, S; Olson, AC; Vogler, WR, 1990) |
| "Chromosome abnormalities were present in cells from 12% (7/60) of the UC colonies, but there was no apparent relationship between colony diameter and the presence of chromosomal abnormalities." | 1.28 | Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures. ( Blazak, WF; Caspary, WJ; Los, FJ; Rudd, CJ, 1989) |
| "and thymidine treatments may be due to thymidine-induced nucleotide pool imbalance with consequent inaccuracies in DNA repair." | 1.27 | Synergism between U.V. and thymidine treatments in the induction of cytogenetic damage in wild-type Friend erythroleukaemia cells. ( McKelvey, VJ; McKenna, PG, 1988) |
| " The dose-response relationships of 32PO4 incorporation into phosphatidic acid and phosphatidylinositol and [3H] thymidine uptake were nearly identical in BCL1 cells." | 1.27 | Changes in phospholipid metabolism during B lymphocyte activation. ( Kriz, MK; Sullivan, TJ; Vitetta, ES, 1986) |
| "Hydroxyurea was more effective than dThd at equimolar concentrations in increasing the acid-soluble Ara-C pool." | 1.26 | Synergistic interaction between 1-beta-D-arabinofuranosylcytosine, thymidine, and hydroxyurea against human B cells and leukemic blasts in vitro. ( Howell, SB; Streifel, JA, 1981) |
| "Thymidine transport was also examined in lymphocytes from several AK x L recombinant inbred mouse strains derived from the cross AKR/J x C57L/J." | 1.26 | Plasma membrane mediated thymidine transport in AKR spleen cells. ( Sheehan, JM; Strauss, PR; Taylor, J, 1980) |
| "Chartreusin was lethal to both L1210 and P388 cells in culture with 90% of the cells being killed after a 24-hr exposure to 1." | 1.26 | Effects of chartreusin on cell survival and cell cycle progression. ( Bhuyan, BK; Bono, VH; Dion, RL; Robinson, MI; Shugars, KD, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 222 (95.69) | 18.7374 |
| 1990's | 8 (3.45) | 18.2507 |
| 2000's | 2 (0.86) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hakimelahi, GH | 1 |
| Ly, TW | 1 |
| Moosavi-Movahedi, AA | 1 |
| Jain, ML | 1 |
| Zakerinia, M | 1 |
| Davari, H | 1 |
| Mei, HC | 1 |
| Sambaiah, T | 1 |
| Moshfegh, AA | 1 |
| Hakimelahi, S | 1 |
| Hegazy, AN | 1 |
| Klein, C | 1 |
| BENDICH, A | 1 |
| BORENFREUND, E | 1 |
| ITTENSOHN, OL | 1 |
| HUTCHISON, DJ | 1 |
| VESELY, J | 4 |
| KANEKO, JJ | 1 |
| NAKAJIMA, H | 1 |
| SCHALM, OW | 1 |
| DELAMORE, IW | 1 |
| PRUSOFF, WH | 3 |
| SILBER, R | 1 |
| COX, RP | 1 |
| HADDAD, JR | 1 |
| FRIEND, C | 3 |
| Lett, JT | 1 |
| Caldwell, I | 1 |
| Dean, CJ | 1 |
| Alexander, P | 2 |
| Watanabe, I | 2 |
| Okada, S | 17 |
| Goncharova, SA | 4 |
| Lipchina, LP | 6 |
| Frankfurt, OS | 5 |
| Aleshchenko, AV | 1 |
| Yeh, CJ | 1 |
| Faulk, WP | 1 |
| Pavelić, K | 1 |
| Sirotković, M | 1 |
| Kopitar, M | 1 |
| Pavelić, J | 1 |
| Vuk-Pavlović, S | 1 |
| Maybaum, J | 1 |
| Ullman, B | 1 |
| Mandel, HG | 1 |
| Day, JL | 1 |
| Sadee, W | 1 |
| Xu, YT | 1 |
| Du, CZ | 1 |
| Grossie, VB | 1 |
| Valdivieso, M | 1 |
| Drewinko, B | 1 |
| Loo, TL | 1 |
| Uitendaal, MP | 1 |
| Schornagel, JH | 1 |
| Leyva, A | 1 |
| Pinedo, HM | 1 |
| Roess, DA | 1 |
| Ruh, TS | 1 |
| Bellone, CJ | 1 |
| Ruh, MF | 1 |
| Simon, JD | 1 |
| Freed, BM | 1 |
| Davignon, D | 1 |
| Albala, MM | 1 |
| Torrent-Quetglas, M | 1 |
| Grau-Oliete, MR | 1 |
| Rivera-Fillat, MP | 1 |
| Schönenberger, H | 1 |
| Wappes, B | 1 |
| Jennerwein, M | 1 |
| Berger, M | 1 |
| Moore-Brown, MM | 1 |
| Clive, D | 1 |
| Howard, BE | 1 |
| Batson, AG | 1 |
| Johnson, KO | 1 |
| Lawson, AD | 1 |
| Stevenson, GT | 1 |
| Tidwell, T | 1 |
| Guzman, G | 1 |
| Vogler, WR | 2 |
| Sonneveld, P | 1 |
| van Gelder, TC | 1 |
| van Bekkum, DW | 1 |
| Streifel, JA | 1 |
| Howell, SB | 1 |
| Lin, TS | 2 |
| Fischer, PH | 2 |
| Marsh, JC | 1 |
| Hiller, K | 1 |
| Meyer, P | 1 |
| Wilms, K | 1 |
| Chou, TC | 2 |
| Burchenal, JH | 2 |
| Schmid, FA | 1 |
| Braun, TJ | 1 |
| Su, TL | 1 |
| Watanabe, KA | 2 |
| Fox, JJ | 2 |
| Philips, FS | 1 |
| Woodcock-Mitchell, J | 1 |
| Yang, TJ | 2 |
| Kessel, D | 9 |
| Butler, WB | 1 |
| Iyer, VK | 1 |
| Horwitz, JP | 1 |
| Sawada, S | 3 |
| Enomoto, T | 1 |
| Kapp, LN | 3 |
| Strauss, PR | 1 |
| Sheehan, JM | 1 |
| Taylor, J | 1 |
| Svirnovskiĭ, AI | 1 |
| Shimanskaia, TV | 1 |
| Ageĭchik, VM | 1 |
| Levin, VI | 1 |
| Hall, IH | 1 |
| Lee, KH | 1 |
| Okano, M | 1 |
| Sims, D | 1 |
| Ibuka, T | 1 |
| Liou, YF | 1 |
| Imakura, Y | 1 |
| Rogers, AM | 1 |
| Hill, R | 1 |
| Lehmann, AR | 1 |
| Arlett, CF | 1 |
| Burns, VW | 1 |
| Lo, SC | 1 |
| Ross, J | 1 |
| Mueller, GC | 1 |
| Petrini, M | 1 |
| Mattii, L | 1 |
| Valentini, P | 1 |
| Sabbatini, AR | 1 |
| Grassi, B | 1 |
| Grandi, M | 1 |
| Abubakar, AA | 1 |
| Riches, AC | 1 |
| Kratz, F | 1 |
| Beyer, U | 1 |
| Collery, P | 1 |
| Lechenault, F | 1 |
| Cazabat, A | 1 |
| Schumacher, P | 1 |
| Falken, U | 1 |
| Unger, C | 1 |
| Hirschman, SZ | 1 |
| Fischinger, PJ | 1 |
| O'Connor, TE | 1 |
| Cihák, A | 2 |
| Strober, S | 1 |
| Gronowicz, ES | 1 |
| Knapp, MR | 1 |
| Slavin, S | 1 |
| Vitetta, ES | 2 |
| Warnke, RA | 1 |
| Kotzin, B | 1 |
| Schröder, J | 1 |
| Ensminger, WD | 1 |
| Greenberger, JS | 1 |
| Egan, EM | 1 |
| Muse, MB | 1 |
| Moloney, WC | 1 |
| Moran, RG | 2 |
| Mulkins, M | 1 |
| Heidelberger, C | 5 |
| Foa, P | 1 |
| Paile, W | 1 |
| Yuen, TL | 1 |
| Jones, WA | 1 |
| Jänne, J | 1 |
| Rytömaa, T | 1 |
| Parkhurst, JR | 1 |
| Danenberg, PV | 1 |
| Santelli, G | 2 |
| Valeriote, F | 2 |
| Preisler, H | 2 |
| Shoham, D | 1 |
| Ho, YK | 1 |
| Preisler, HD | 2 |
| Bardos, TJ | 1 |
| Lengle, EE | 1 |
| Gustin, NC | 1 |
| Gonzalez, F | 1 |
| Menahan, LA | 1 |
| Kemp, RG | 1 |
| Bendinelli, M | 1 |
| Friedman, H | 2 |
| Lee, KC | 1 |
| Berry, D | 1 |
| Clarkson, BD | 1 |
| Fried, J | 1 |
| Strife, A | 1 |
| Ferguson, R | 1 |
| Sullivan, S | 1 |
| Kitahara, T | 1 |
| Oyama, A | 1 |
| Kmieck, PJ | 1 |
| Bagwell, CB | 1 |
| Hudson, JL | 1 |
| Irvin, GL | 1 |
| Engelbert, VE | 1 |
| Beer, JZ | 2 |
| Budzicka, E | 2 |
| Szumiel, I | 2 |
| Walicka, M | 2 |
| Bhuyan, BK | 1 |
| Robinson, MI | 1 |
| Shugars, KD | 1 |
| Bono, VH | 2 |
| Dion, RL | 1 |
| Wohlhueter, RM | 1 |
| Marz, R | 1 |
| Plagemann, PG | 1 |
| Grindey, GB | 2 |
| Wang, MC | 1 |
| Kinhan, JJ | 1 |
| Kondrat'eva, NA | 1 |
| Dobrynin, IaV | 1 |
| Merkulov, MF | 1 |
| Harriss, EB | 5 |
| Hoelzer, D | 5 |
| Yoshida, M | 2 |
| Hoshi, A | 3 |
| Kuretani, K | 3 |
| Buell, DN | 1 |
| Fowlkes, BJ | 1 |
| Metzher, H | 1 |
| Isersky, C | 1 |
| Calderon, J | 2 |
| Unanue, ER | 2 |
| Christie, GH | 1 |
| Bomford, R | 1 |
| Wolpert-Defilippes, MK | 1 |
| Adamson, RH | 3 |
| Cysyk, RL | 1 |
| Johns, DG | 1 |
| Nakazawa, N | 1 |
| Makino, F | 1 |
| Belton, JG | 1 |
| Kanai, T | 2 |
| Ichino, M | 2 |
| Sassa, S | 1 |
| Ciovacco, K | 1 |
| Kalaher, K | 1 |
| O'Toole, T | 1 |
| Kiefner, R | 1 |
| Dowling, MD | 1 |
| Chu, CK | 1 |
| Wempen, I | 1 |
| Smadja-Joffe, F | 2 |
| Klein, B | 1 |
| Kerdiles, C | 1 |
| Feinendegen, L | 1 |
| Jasmin, C | 2 |
| Okunewick, JP | 2 |
| Phillips, EL | 2 |
| Brozovich, B | 1 |
| Yoshida, T | 1 |
| Ishida, Y | 1 |
| Sasaki, H | 1 |
| Inoue, T | 1 |
| Kaku, K | 1 |
| Kaneko, T | 1 |
| Bruno, JG | 1 |
| Olson, GB | 1 |
| Majumdar, SK | 1 |
| Daly, EP | 1 |
| Kleemeyer, KM | 1 |
| Daehler, CC | 1 |
| Baker, MA | 1 |
| Postoak, D | 1 |
| Nystuen, L | 1 |
| King, L | 1 |
| Ueno, M | 1 |
| Beckman, BS | 2 |
| Olson, AC | 1 |
| Berdel, WE | 1 |
| Okamoto, S | 1 |
| Glasser, L | 1 |
| Elliott, RD | 1 |
| Brockman, RW | 1 |
| Montgomery, JA | 1 |
| Amacher, DE | 1 |
| Turner, GN | 1 |
| Moore, MM | 1 |
| Applegate, ML | 1 |
| Hozier, JC | 1 |
| Blazak, WF | 1 |
| Los, FJ | 1 |
| Rudd, CJ | 1 |
| Caspary, WJ | 1 |
| Kapiszewska, M | 1 |
| Lange, CS | 1 |
| Tsvetkov, S | 1 |
| Ivanova, E | 1 |
| Djondjurov, L | 1 |
| Abkowitz, JL | 1 |
| Holly, RD | 1 |
| Adamson, JW | 1 |
| Riva, CM | 1 |
| Rustum, YM | 1 |
| Tavares, L | 1 |
| Roneker, C | 1 |
| Johnston, K | 1 |
| Lehrman, SN | 1 |
| de Noronha, F | 1 |
| Oberly, TJ | 1 |
| Bewsey, BJ | 1 |
| Probst, GS | 1 |
| Kopfler, W | 1 |
| Koury, P | 1 |
| Jeter, JR | 1 |
| Miller, B | 1 |
| Tenenholz, T | 1 |
| Egorin, MJ | 1 |
| Sosnovsky, G | 1 |
| Rao, NU | 1 |
| Gutierrez, PL | 1 |
| McKelvey, VJ | 1 |
| McKenna, PG | 1 |
| Satyamoorthy, K | 2 |
| Chitnis, MP | 3 |
| Ruscetti, SK | 1 |
| Kriz, MK | 1 |
| Sullivan, TJ | 1 |
| Kamath, NS | 1 |
| Bhalla, K | 1 |
| Grant, S | 1 |
| Pradhan, SG | 1 |
| Basrur, VS | 1 |
| Tantri, SK | 1 |
| Bogush, TA | 1 |
| Donenko, FV | 1 |
| Saprykina, NS | 1 |
| Rowley, PT | 1 |
| Ohlsson-Wilhelm, BM | 1 |
| Tanaka, M | 1 |
| Kimura, K | 1 |
| Fuska, J | 1 |
| Fusková, A | 1 |
| Proksa, B | 1 |
| Plunkett, W | 1 |
| Desgranges, C | 1 |
| Razaka, G | 1 |
| De Clercq, E | 1 |
| Herdewijn, P | 1 |
| Balzarini, J | 1 |
| Drouillet, F | 1 |
| Bricaud, H | 1 |
| Chitnis, M | 1 |
| Menon, R | 1 |
| Adwankar, M | 1 |
| Grancharov, KC | 1 |
| Gorneva, GA | 1 |
| Spassova, MK | 1 |
| Mladenova, JP | 1 |
| Knyszynski, A | 2 |
| Burger, M | 2 |
| Nayak, DP | 1 |
| Goldstein, R | 2 |
| Lieberman, D | 1 |
| Voloch, Z | 1 |
| Aviv, H | 1 |
| Nudel, U | 1 |
| Revel, M | 1 |
| McCulloch, EA | 1 |
| Mak, TW | 1 |
| Price, GB | 1 |
| Till, JE | 1 |
| Abdel-Wahab, KS | 1 |
| Booden, T | 1 |
| Albach, RA | 1 |
| Wilson, DA | 1 |
| Momparler, RL | 1 |
| Chu, MY | 2 |
| Fischer, GA | 4 |
| Uematsu, K | 1 |
| Huggins, C | 1 |
| Whyatt, PL | 1 |
| Cramer, JW | 1 |
| Williams, RT | 1 |
| Neubert, D | 1 |
| Oberdisse, E | 2 |
| Merker, HJ | 1 |
| Köhler, E | 1 |
| Balda, BR | 1 |
| Helge, H | 1 |
| Engels, K | 1 |
| Kummer, D | 1 |
| Ochs, HD | 1 |
| Fujiwara, Y | 3 |
| Petrányi, GG | 1 |
| Klein, E | 1 |
| Svedmyr, E | 1 |
| Jacobsson, H | 1 |
| Rodey, GE | 1 |
| Sprader, JC | 1 |
| Bortin, MM | 1 |
| Hildebrand, J | 1 |
| Thys, O | 1 |
| Atassi, G | 1 |
| Debusscher, L | 1 |
| Tagnon, HJ | 1 |
| Khwaja, TA | 1 |
| Umeda, M | 1 |
| Durham, JP | 1 |
| Ives, DH | 1 |
| Bosmann, HB | 7 |
| Maruyama, K | 1 |
| Dmochowski, L | 1 |
| Stadler, JK | 1 |
| Adelberg, EA | 1 |
| Gross, PA | 1 |
| Fong, CK | 1 |
| Hsiung, CD | 1 |
| Derge, JG | 1 |
| Martos, LM | 1 |
| Tagamets, MA | 1 |
| Chang, SY | 1 |
| Chakrabarty, M | 1 |
| Fredrickson, TN | 1 |
| Schultz, EF | 1 |
| LoBue, J | 1 |
| Rubin, AD | 1 |
| Gordon, AS | 1 |
| Schmidt, M | 1 |
| Seidel, HJ | 1 |
| Anaclerio, A | 1 |
| Waterfield, JD | 1 |
| Möller, G | 1 |
| Jäger, C | 2 |
| Cline, MJ | 2 |
| Metcalf, D | 2 |
| Ostertag, W | 1 |
| Crozier, T | 1 |
| Kluge, N | 1 |
| Melderis, H | 1 |
| Dube, S | 1 |
| Vilpo, JA | 1 |
| Dunn, BP | 1 |
| Gout, PW | 1 |
| Beer, CT | 1 |
| Haas, RJ | 2 |
| Fliedner, TM | 1 |
| Scher, W | 2 |
| Roots, R | 1 |
| Tattersall, MH | 1 |
| Harrap, KR | 1 |
| Shevach, EM | 2 |
| Ellman, L | 2 |
| Davie, JM | 1 |
| Green, I | 3 |
| Shevach, E | 1 |
| Maillard, J | 1 |
| Strauss, RR | 1 |
| Jacobs, AA | 1 |
| Paul, BB | 1 |
| Sbarra, AJ | 1 |
| Mortensen, RF | 1 |
| Ceglowski, WS | 1 |
| Paul, WE | 1 |
| Shinohara, K | 1 |
| Konovalova, NP | 1 |
| Shevtsova, VN | 1 |
| Kondo, T | 1 |
| Kawamoto, Y | 1 |
| Uchiyama, C | 1 |
| Schmitt, G | 1 |
| Kaufmann, H | 1 |
| Löhr, E | 1 |
| Nagaya, H | 1 |
| Stith, WJ | 1 |
| Hodgins, DS | 1 |
| Abell, CW | 1 |
| Heby, O | 1 |
| Sarna, GP | 1 |
| Marton, LJ | 1 |
| Omine, M | 1 |
| Perry, S | 1 |
| Russell, DH | 1 |
| Kanzawa, F | 1 |
| Barr, DH | 1 |
| Harris, JW | 1 |
| Holland, JG | 1 |
| Malaise, EP | 1 |
| Bournoutian, C | 1 |
| Hyodo, M | 1 |
| Eberle, H | 1 |
| Butenko, ZA | 1 |
| Tidd, DM | 1 |
| Paterson, AR | 1 |
| Turnell, RW | 1 |
| Burton, AF | 1 |
| Seeber, S | 1 |
| Warnecke, P | 1 |
| Straub, OC | 1 |
| Cole, RS | 1 |
| Roberts, D | 2 |
| Gallo, RC | 1 |
| Whang-Peng, J | 1 |
| Hryniuk, WM | 3 |
| Fabrikant, JI | 1 |
| Foster, BR | 1 |
| Finklestein, JZ | 1 |
| Byfield, J | 1 |
| Tittle, K | 1 |
| Imagawa, DT | 1 |
| Cooper, GM | 1 |
| Dunning, WF | 1 |
| Greer, S | 1 |
| Vas, SI | 1 |
| Lohr, K | 1 |
| Meltz, M | 1 |
| Hashimoto, Y | 1 |
| Sudo, H | 1 |
| Apple, MA | 1 |
| Hagemann, RF | 1 |
| Sugiyama, T | 1 |
| Handschumacher, RE | 1 |
| Bates, CJ | 1 |
| Chang, PK | 1 |
| Andrews, AT | 1 |
| Bertino, JR | 3 |
| Fox, M | 1 |
| Gilbert, CW | 1 |
| O'Brien, P | 1 |
| McCullough, JL | 1 |
| Hall, TC | 1 |
| Reyes, P | 1 |
| Cooper, EH | 1 |
| Wodinsky, I | 3 |
| Bernacki, RJ | 2 |
| Burki, HJ | 2 |
| Oki, T | 1 |
| Miller, HK | 1 |
| Krakoff, IH | 1 |
| Salser, JS | 1 |
| Balis, ME | 1 |
| Hibberd, AD | 1 |
| Old, LJ | 1 |
| Stockert, E | 1 |
| Boyse, EA | 1 |
| Kim, JH | 1 |
| Hart, LG | 1 |
| DeVita, VT | 1 |
| Oliverio, VT | 1 |
| Kohn, KW | 1 |
| Kann, HE | 1 |
| Hill, M | 2 |
| Spurná, V | 2 |
| Veatch, W | 1 |
| Zeleznick, LD | 1 |
| Doida, Y | 1 |
| Myers, M | 1 |
| Börzsönyi, M | 1 |
| Lapis, K | 1 |
| Varga, L | 1 |
| Várterész, V | 1 |
| Billen, D | 1 |
| Lapthisophon, T | 1 |
| Frampton, EW | 1 |
| Sheek, MR | 1 |
| Nelson, DJ | 1 |
| Carter, CE | 1 |
| Sorm, F | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma[NCT04923529] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for thymidine and Experimental Leukemia
| Article | Year |
|---|---|
Immunobiology of a spontaneous murine B cell leukemia (BCL1).
Topics: Animals; B-Lymphocytes; Cell Transformation, Neoplastic; Immunoglobulin Light Chains; Immunoglobulin | 1979 |
Functional heterogeneity in macrophages activated by Corynebacterium parvum: characterization of subpopulations with different activities in promoting immune responses and suppressing tumor cell growth.
Topics: Animals; Ascitic Fluid; Cell Division; Cell Separation; Cells, Cultured; Erythrocytes; Female; Immun | 1977 |
Duration of the dormant state in an established cell line of human hematopoietic cells.
Topics: Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Line; Cell Survival; Clone Cells; Cy | 1977 |
Alternatives to classical mitosis in hemopoietic tissues of vertebrates.
Topics: Animals; Bone Marrow; Cell Differentiation; Cell Division; Cell Nucleus; Cells, Cultured; Clone Cell | 1979 |
In search of a key.
Topics: Animals; Antineoplastic Agents; Cells, Cultured; Cricetinae; DNA, Neoplasm; Drug Combinations; Human | 1971 |
Relevance of in vitro tests for predicting responsiveness to antitumor agents.
Topics: Animals; Antineoplastic Agents; Cell Line; Cell Membrane Permeability; DNA, Neoplasm; Drug Resistanc | 1971 |
1 trial available for thymidine and Experimental Leukemia
| Article | Year |
|---|---|
Inhibition of adenosine deaminase to increase the antitumor activity of adenine nucleoside analogues.
Topics: Adenine; Adenosine Deaminase Inhibitors; Adult; Animals; Carcinoma, Ehrlich Tumor; Clinical Trials a | 1985 |
225 other studies available for thymidine and Experimental Leukemia
| Article | Year |
|---|---|
Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses.
Topics: Adenine; Adenine Nucleotides; Adenosine Deaminase Inhibitors; Animals; Antineoplastic Agents; Antivi | 2001 |
Ex vivo priming of CD4 T cells converts immunological tolerance into effective antitumor immunity in a murine model of acute lymphoblastic leukemia.
Topics: Animals; CD4-Positive T-Lymphocytes; Cell Proliferation; Dendritic Cells; Disease Models, Animal; Fe | 2008 |
UPTAKE OF MAMMALIAN CHROMOSOMES BY MAMMALIAN CELLS.
Topics: Animals; Autoradiography; Cell Nucleus; Chromosomes; Chromosomes, Mammalian; Coloring Agents; Cytopl | 1963 |
THE INCORPORATION OF THE TRITIATED THYMIDINE INTO DEOXYRIBONUCLEIC ACID OF MOUSE LEUKEMIC CELLS.
Topics: Animals; Autoradiography; Cell Nucleus; DNA; DNA, Neoplasm; Leukemia; Leukemia, Experimental; Metabo | 1963 |
THE BOVINE LEUKOCYTE--LEUKOKINETIC STUDIES IN NORMAL, LEUKEMIC, AND MASTITIC COWS.
Topics: Animals; Cattle; DNA; Female; Leukemia; Leukemia, Experimental; Leukocytes; Mastitis; Mastitis, Bovi | 1964 |
THE GENERATION TIME OF THE LEUKEMIC MYELOBLASTS IN VIVO IN FOWL LEUKEMIA.
Topics: Animals; Autoradiography; Cell Division; DNA; DNA, Neoplasm; Granulocyte Precursor Cells; Leukemia; | 1963 |
EFFECT OF DEOXYCYTIDINE ON THE RATE OF BIOSYNTHESIS OF PHOSPHORYLATED DERIVATIVES OF THYMIDINE.
Topics: Carbon Isotopes; Chromatography; Deoxycytidine; Formates; Idoxuridine; Leukemia; Leukemia, Experimen | 1964 |
ENZYME STUDIES IN VIRUS-INDUCED NEOPLASMS. I. THE EFFECT OF A MURINE LEUKEMIA ON ENZYMES OF ONE-CARBON METABOLISM AND ON PHOSPHOMONOESTERASES.
Topics: Alkaline Phosphatase; Animals; Carbon; Esterases; Folic Acid; Histocytochemistry; Leukemia; Leukemia | 1964 |
Rejoining of x-ray induced breaks in the DNA of leukaemia cells.
Topics: Animals; DNA, Neoplasm; Leukemia, Experimental; Mice; Micrococcus; Molecular Weight; Nitrogen; Oxyge | 1967 |
Stationary phase of cultured mammalian cells (L5178Y).
Topics: Animals; Carbon Isotopes; Cell Nucleus; Culture Techniques; Leukemia, Experimental; Mice; Mitosis; T | 1967 |
[Radioautographic studies of inoculated leukemia in mice].
Topics: Animals; Autoradiography; DNA, Neoplasm; Leukemia, Experimental; Liver; Male; Mice; Neoplasm Transpl | 1967 |
[Mitotic cycles of leukemic cells].
Topics: Animals; DNA, Neoplasm; Humans; Leukemia; Leukemia, Experimental; Lymphocytes; Lymphoma; Mice; Mitos | 1967 |
[Autoradiographic studies of the effects of x-irradiation on ascitic lymphatic leukemia cells in mice].
Topics: Animals; Autoradiography; DNA, Neoplasm; Leukemia, Experimental; Mice; Mitosis; Radiation Effects; T | 1967 |
Killing of human tumor cells in culture with adriamycin conjugates of human transferrin.
Topics: Animals; Cell Membrane; Cell Nucleus; Cell Survival; Doxorubicin; Fluorescent Antibody Technique; Hu | 1984 |
Murine myeloid leukemia: in vivo suppression by sericystatin A, a proteinase inhibitor from leukocytes.
Topics: Animals; Cells, Cultured; Cystatin A; Cystatins; Insulin; Leukemia, Experimental; Leukemia, Myeloid; | 1983 |
Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.
Topics: Animals; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Leu | 1980 |
[Effect of harringtonine and its allied alkaloids on DNA synthesis in mice bearing leukemias P388. L615 and normal mice (author's transl)].
Topics: Alkaloids; Animals; Bone Marrow; DNA; DNA, Neoplasm; Harringtonines; Leukemia, Experimental; Mice; M | 1981 |
Effect of thymidine on the toxicity and antitumor activity of cis-diamminedichloroplatinum (II).
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cisplatin; Drug Interactions; | 1984 |
Influence of concomitant infusion of thymidine and inosine on methotrexate activity in normal and P388-bearing mice.
Topics: Animals; Drug Synergism; Female; Infusions, Parenteral; Inosine; Leukemia L1210; Leukemia P388; Leuk | 1984 |
Glucocorticoid effects on lipopolysaccharide-stimulated murine B-cell leukemia line (BCL1) cells.
Topics: Animals; B-Lymphocytes; Glucocorticoids; Leukemia, Experimental; Lipopolysaccharides; Male; Mice; Mi | 1983 |
Identification and characterization of a soluble suppressor factor(s) in the serum of AKR mice bearing lymphocytic leukemia.
Topics: Animals; B-Lymphocytes; Blood Physiological Phenomena; Cell Line; Female; Humans; Leukemia, Experime | 1983 |
Uptake of thymidine by plasma membrane vesicles of L5178Y murine leukemic cells.
Topics: Animals; Binding Sites; Biological Transport; Cell Membrane; Kinetics; Leukemia L5178; Leukemia, Exp | 1984 |
Development of selectively acting platinum complexes.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Chromatin; DNA; Female; Humans; In Vitro Technique | 1984 |
The utilization of trifluorothymidine (TFT) to select for thymidine kinase-deficient (TK-/-) mutants from L5178Y/TK+/- mouse lymphoma cells.
Topics: Animals; Bromodeoxyuridine; Cell Separation; Dose-Response Relationship, Drug; Leukemia L5178; Leuke | 1981 |
Macrophages induce antibody-dependent cytostasis but not lysis in guinea pig leukaemic cells.
Topics: Animals; Antibodies, Neoplasm; Antibody-Dependent Cell Cytotoxicity; Cell Division; Cell Line; Chick | 1983 |
The effects of alkyl-lysophospholipids on leukemic cell lines. I. Differential action on two human leukemic cell lines, HL60 and K562.
Topics: Animals; Bone Marrow; Cell Line; Clone Cells; Colony-Forming Units Assay; Dose-Response Relationship | 1981 |
Antileukemic effect of high-dose thymidine in a rat model for acute myeloid leukemia (BNML).
Topics: Animals; Colony-Forming Units Assay; Dose-Response Relationship, Drug; Female; Injections, Intraperi | 1981 |
Synergistic interaction between 1-beta-D-arabinofuranosylcytosine, thymidine, and hydroxyurea against human B cells and leukemic blasts in vitro.
Topics: Animals; B-Lymphocytes; Cells, Cultured; Cytarabine; DNA Replication; DNA, Neoplasm; Drug Synergism; | 1981 |
Effect of 3'-amino-3'-deoxythymidine on L1210 and P388 leukemias in mice.
Topics: Animals; Antineoplastic Agents; Dideoxynucleosides; Drug Administration Schedule; Female; Leukemia L | 1982 |
Antitumor activity of the 3'-chloroethylnitrosourea analog of thymidine and the prevention by co-administered thymidine of lethality but not of anticancer activity.
Topics: Animals; Antineoplastic Agents; Body Weight; Bone Marrow; Dideoxynucleosides; Drug Interactions; Fem | 1982 |
In vivo cell kinetic effects of vincristine on the spontaneous AKR leukemia: recruitment of non-proliferating cells.
Topics: Animals; Female; Leukemia, Experimental; Mice; Mice, Inbred AKR; Mitosis; Spleen; Thymidine; Thymus | 1982 |
Biochemical effects of 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil and 2'-fluoro-5-iodo-1-beta-D-arabinofuranosylcytosine in mouse leukemic cells sensitive and resistant to 1-beta-D-arabinofuranosylcytosine.
Topics: Animals; Arabinofuranosyluracil; Cell Survival; Cytarabine; Deoxycytidine; DNA Replication; Kinetics | 1982 |
Effect of antiserum on leukemia L5178Y cells: [3H]thymidine incorporation does not reflect DNA synthesis.
Topics: Animals; Antibodies, Neoplasm; Biological Transport; DNA Replication; DNA, Neoplasm; Folic Acid; Leu | 1982 |
Estrogen-bridged purines: a new series of anti-tumor agents which alter cell membrane properties.
Topics: Animals; Biological Transport; Cell Membrane; Cycloleucine; DNA Replication; Doxorubicin; Drug Evalu | 1982 |
Relationship between DNA chain growth termination and replicon sizes in gamma-irradiated mouse cells.
Topics: Animals; Autoradiography; Cells, Cultured; DNA, Neoplasm; Gamma Rays; Leukemia L5178; Leukemia, Expe | 1982 |
Plasma membrane mediated thymidine transport in AKR spleen cells.
Topics: Adenosine; Age Factors; Animals; Biological Transport; Cell Membrane; Concanavalin A; Kinetics; Leuk | 1980 |
[Inhibition of DNA synthesis in vitro in normal and leukemic spleen cells after administration of a lyophilized aqueous extract of normal spleen tissue].
Topics: Animals; Cattle; DNA; DNA, Neoplasm; In Vitro Techniques; Leukemia, Experimental; Lymphocyte Activat | 1981 |
Antitumor agents XLII: Comparison of antileukemic activity of helenalin, brusatol, and bruceantin and their esters on different strains of P-388 lymphocytic leukemic cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cells, Cultured; DNA, Neoplasm; Glaucarubin; Leukemia P3 | 1981 |
The induction and characterization of mouse lymphoma L5178Y cell lines resistant to 1-beta-d-arabinofuranosylcytosine.
Topics: 2-Acetylaminofluorene; Animals; Cell Line; Cytarabine; Drug Resistance; Ethidium; Ethyl Methanesulfo | 1980 |
Localization of globin gene replication in Friend Leukemia cells to a specific interval of the S phase.
Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Line; DNA Replication; DNA, Neoplasm; Genes; Globins; H | 1980 |
Idarubicin is active on MDR cells: evaluation of DNA synthesis inhibition on P388 cell lines.
Topics: Animals; DNA; Doxorubicin; Drug Resistance; Idarubicin; Leukemia, Experimental; Mice; Thymidine; Tri | 1993 |
A possible correlation between growth-factor sensitivity and response to mitoxantrone treatment in a murine myeloid leukaemia (SA7HD) cell line.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Cell Count; Cell Division; Culture Media, Conditioned; | 1997 |
Preparation, characterization and in vitro efficacy of albumin conjugates of doxorubicin.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Bromodeoxyuridine; Chromatography, High Pressure Liqu | 1998 |
Effect of infection with Moloney sarcoma and leukemia viruses on nucleic acid synthesis in mouse cell cultures.
Topics: 3T3 Cells; Animals; Carbon Radioisotopes; DNA, Neoplasm; Leukemia, Experimental; Mice; Moloney murin | 1970 |
Incorporation of a potent antileukemic agent, 5-aza-2'-deoxycytidine, into DNA of cells from leukemic mice.
Topics: Animals; Azacitidine; Deoxycytidine; Epithelium; Female; Leukemia L1210; Leukemia, Experimental; Liv | 1977 |
Technique for preclinical evaluation of continuous infusion chemotherapy with the use of WF rat acute myelogenous leukemia.
Topics: Animals; Antineoplastic Agents; Cytarabine; Dose-Response Relationship, Drug; Doxorubicin; Drug Admi | 1979 |
Role of thymidylate synthetase activity in development of methotrexate cytotoxicity.
Topics: Animals; Cell Division; Cells, Cultured; Floxuridine; Humans; Hypoxanthines; Leucovorin; Leukemia, E | 1979 |
Granulocytic chalone is not a polyamine complex.
Topics: Animals; Bone Marrow; Granulocytes; Growth Inhibitors; Humans; Leukemia L1210; Leukemia, Experimenta | 1979 |
Growth inhibition of cells in cultures and of vaccinia virus infected HeLa cells by derivatives of trifluorothymidine.
Topics: Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Depression, Chemical; HeLa Cells; Leuk | 1976 |
In vivo enhancement of 5-fluorouracil cytotoxicity to AKR leukemia cells by thymidine in mice.
Topics: Animals; Cell Survival; Colony-Forming Units Assay; Drug Synergism; Drug Therapy, Combination; Femal | 1978 |
Comparison of tritiated thymidine labeling and suicide indices in acute nonlymphocytic leukemia.
Topics: Animals; Bone Marrow; Cell Cycle; Cell Division; Cell Survival; Clone Cells; Colony-Forming Units As | 1978 |
Effects of partially thiolated polycytidylic acid on the clonogenicity of murine leukemic stem cells.
Topics: Animals; Cell Cycle; Cell Division; Clone Cells; Colony-Forming Units Assay; Hematopoietic Stem Cell | 1979 |
Energy metabolism in thymic lymphocytes of normal and leukemia AKR mice.
Topics: Age Factors; Animals; Energy Metabolism; Glucose; Glycolysis; In Vitro Techniques; Lactates; Leukemi | 1978 |
B and T lymphocyte activation by murine leukemia virus infection.
Topics: Animals; Antibody Formation; B-Lymphocytes; Erythrocytes; Friend murine leukemia virus; Leukemia, Ex | 1979 |
Multiparameter kinetic analysis of killer cell initiation by using immune RNA.
Topics: Animals; Cell Cycle; Cell Line; Cytological Techniques; Cytotoxicity, Immunologic; Leukemia, Experim | 1979 |
Post-exposure phenomen in murine lymphoma L5178Y-S cell populations grown in media containing tritiated compounds.
Topics: Animals; Cell Survival; Cells, Cultured; Leukemia, Experimental; Lymphoma; Lysine; Mice; Radiation D | 1978 |
Susceptibility of L5178Y-R and L5178Y-S cells to HTO, 3H-lysine and 3H-thymidine exposure.
Topics: Animals; Cell Survival; Cells, Cultured; Electrons; Leukemia, Experimental; Lymphoma; Lysine; Mice; | 1978 |
Effects of chartreusin on cell survival and cell cycle progression.
Topics: Animals; Antibiotics, Antineoplastic; Benzopyrans; Cell Cycle; Cell Survival; Cells, Cultured; Demec | 1978 |
Properties of the thymidine transport system of Chinese hamster ovary cells as probed by nitrobenzylthioinosine.
Topics: Animals; Biological Transport, Active; Female; HeLa Cells; Hypoxanthines; Inosine; Kinetics; L Cells | 1978 |
Thymidine induced perturbations in ribonucleoside and deoxyribonucleoside triphosphate pools in human leukemic CCRF-CEM cells.
Topics: Animals; Cells, Cultured; Deoxyribonucleotides; Humans; Leukemia, Experimental; Ribonucleotides; Thy | 1979 |
[Cellular test system for studying the biological properties of preparations with L-asparaginase activity].
Topics: Animals; Antineoplastic Agents; Asparaginase; Biological Assay; Burkitt Lymphoma; Cells, Cultured; C | 1977 |
Proliferative state of normal in vitro colony-forming cells during development of L5222 rat leukemia and their reaction to chemotherapy.
Topics: Animals; Bone Marrow Cells; Cell Division; Cell Survival; Cells, Cultured; Daunorubicin; Female; Hyd | 1978 |
Prevention of antitumor effect of 5-fluorouracil by hypoxanthine.
Topics: Animals; Cell Division; Cell Line; Fluorouracil; Hypoxanthines; Leukemia, Experimental; Mice; Thymid | 1978 |
Effects of acronycine on cell-surface properties of murine leukemia cells.
Topics: Acronine; Alkaloids; Amino Acids; Anilino Naphthalenesulfonates; Animals; Cadaverine; Cell Membrane; | 1977 |
Cell cycle and morphological changes during growth and differentiation of a rat basophilic leukemia cell line.
Topics: Animals; Basophils; Cell Differentiation; Cell Division; Cell Line; DNA, Neoplasm; Histamine; Leukem | 1976 |
Two biological activities regulating cell proliferation found in cultures of peritoneal exudate cells.
Topics: Animals; Ascitic Fluid; Cells, Cultured; Growth Substances; Lectins; Leukemia, Experimental; Lymphoc | 1975 |
Mechanisms of macrophage activation by Corynebacterium parvum. I. In vitro experiments.
Topics: Animals; Antilymphocyte Serum; Ascitic Fluid; Cells, Cultured; Corynebacterium; DNA; Female; Leukemi | 1975 |
Initial studies on the cytotoxic action of maytansine, a novel ansa macrolide.
Topics: Animals; Antibiotics, Antineoplastic; Cells, Cultured; Leucine; Leukemia L1210; Leukemia, Experiment | 1975 |
Effects of allopurinol on the therapeutic efficacy of methotrexate.
Topics: Allopurinol; Animals; Chick Embryo; Female; Hypoxanthines; Leukemia L1210; Leukemia, Experimental; M | 1975 |
Acute effects of mercuric compounds on cultured mammalian cells.
Topics: Animals; Benzene Derivatives; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Centrifugati | 1975 |
Effects of 4-nitrobenzofurazans and their N-oxides on synthesis of protein and nucleic acid by murine leukemia cells.
Topics: Animals; Benzoxazoles; Cells, Cultured; Cyclic N-Oxides; DNA, Neoplasm; Leukemia L1210; Leukemia, Ex | 1975 |
Action of 5-fluorocyclocytidine on cultured L-5178Y cells.
Topics: Animals; Cell Line; Cytarabine; Deoxyribonucleosides; DNA, Neoplasm; Leucine; Leukemia, Experimental | 1975 |
Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells.
Topics: 5-Aminolevulinate Synthetase; Ammonia-Lyases; Animals; Bromodeoxyuridine; Cell Transformation, Neopl | 1976 |
Antileukemic effects of pseudoisocytidine, a new synthetic pyrimidine C-nucleoside.
Topics: Animals; Cell Line; Cells, Cultured; Cytidine; Deoxycytidine; Drug Evaluation, Preclinical; Isomeris | 1976 |
Study of cell death in Friend leukaemia.
Topics: Animals; Autoradiography; Cell Division; Cell Survival; Female; Idoxuridine; Kinetics; Leukemia, Exp | 1976 |
Effect of Rauscher leukemia development on DNA synthesis by hematopoietic CFU-S.
Topics: Animals; Cell Division; DNA, Neoplasm; Female; Hematopoietic Stem Cells; Leukemia, Experimental; Mic | 1976 |
Expression of high affinity binding sites for erythropoietin on L8057 cells, a mouse megakaryoblastic cell line, associated with cell differentiation.
Topics: Acetylcholinesterase; Animals; Antigens; Cell Differentiation; Cell Transformation, Neoplastic; DNA, | 1992 |
Influence of cell cycle synchronization on digital image analysis of HL-60 granulopoiesis.
Topics: Cell Count; Cell Cycle; Cell Differentiation; Cell Division; DNA, Neoplasm; Granulocytes; Hematopoie | 1992 |
Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells.
Topics: Animals; Cell Division; Cell Membrane; Chromosome Aberrations; DNA Damage; DNA Replication; Gossypol | 1991 |
15-Lipoxygenase products of arachidonate play a role in proliferation of transformed erythroid cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 15-Lipoxygenase; Arachidonic Acids | 1990 |
Purging leukemia remission marrows with alkyl-lysophospholipids, preclinical and clinical results.
Topics: Acute Disease; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplan | 1990 |
Reactive 5'-substituted thymidine derivatives as potential inhibitors of nucleotide biosynthesis.
Topics: Animals; Cells, Cultured; DNA; Half-Life; Leukemia, Experimental; Mice; Nucleic Acid Synthesis Inhib | 1986 |
The mutagenicity of 5-azacytidine and other inhibitors of replicative DNA synthesis in the L5178Y mouse lymphoma cell.
Topics: Animals; Aphidicolin; Azacitidine; Cell Line; Cytidine; Diterpenes; Drug Resistance; Leukemia L5178; | 1987 |
Do trifluorothymidine-resistant mutants of L5178Y mouse lymphoma cells re-express thymidine kinase activity following 5-azacytidine treatment?
Topics: Animals; Azacitidine; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Mice; Mutation; Thymi | 1988 |
Chromosome analysis of small and large L5178Y mouse lymphoma cell colonies: comparison of trifluorothymidine-resistant and unselected cell colonies from mutagen-treated and control cultures.
Topics: Animals; Chromosome Aberrations; Dimethyl Sulfoxide; Hycanthone; Leukemia L5178; Leukemia, Experimen | 1989 |
The effect of hypothermic treatment on the repair or expression of X-ray damage measured in split dose experiments on L5178Y-S cells.
Topics: Animals; Cell Cycle; Cell Survival; DNA Repair; DNA, Neoplasm; Filtration; Leukemia L5178; Leukemia, | 1989 |
The pool of histones in the nucleosol and cytosol of proliferating Friend cells is small, uneven and chasable.
Topics: Animals; Cell Division; Cell Nucleus; Chromatin; Cytosol; DNA Replication; Electrophoresis, Gel, Two | 1989 |
Retrovirus-induced feline pure red cell aplasia: the kinetics of erythroid marrow failure.
Topics: Animals; Bone Marrow; Cats; Cell Division; Erythroblasts; Hematopoietic Stem Cells; Kinetics; Leukem | 1987 |
1-beta-D-arabinofuranosylcytosine metabolism and incorporation into DNA as determinants of in vivo murine tumor cell response.
Topics: Animals; Arabinofuranosylcytosine Triphosphate; Arabinonucleotides; Bone Marrow; Deoxycytidine Kinas | 1985 |
3'-Azido-3'-deoxythymidine in feline leukemia virus-infected cats: a model for therapy and prophylaxis of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Animals; Antibodies, Viral; Antineoplastic Agents; Antiviral Age | 1987 |
Thymidine kinase activity and trifluorothymidine resistance of spontaneous and mutagen-induced L5178Y cells in RPMI 1640 medium.
Topics: Animals; Cell Line; Culture Media; Drug Resistance; Leukemia L5178; Leukemia, Experimental; Methylch | 1986 |
Effect of aphidicolin on Friend erythroleukemia cell maturation.
Topics: Acetamides; Animals; Aphidicolin; Cell Differentiation; Cell Division; Diterpenes; DNA Polymerase II | 1987 |
Cellular pharmacology of N,N',N''-triethylene thiophosphoramide.
Topics: Animals; Cell Division; Cell Survival; DNA Replication; DNA, Neoplasm; Kinetics; Leucine; Leukemia P | 1988 |
Synergism between U.V. and thymidine treatments in the induction of cytogenetic damage in wild-type Friend erythroleukaemia cells.
Topics: Animals; Chromosome Aberrations; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leuk | 1988 |
Hyperthermia blocks reversibility of hydroxyurea and bipyridine induced synergistic inhibition of DNA biosynthesis in P388 murine leukemia cells.
Topics: 2,2'-Dipyridyl; Animals; DNA Replication; Drug Synergism; Hot Temperature; Hydroxyurea; Kinetics; Le | 1988 |
Employment of a [3H]thymidine-incorporation assay to distinguish the effects of different Friend erythroleukemia-inducing retroviruses on erythroid cell proliferation.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Division; Erythrocytes; Erythropoietin; Friend | 1986 |
Changes in phospholipid metabolism during B lymphocyte activation.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Line; Female; Leukemia, Experimental; Lymph | 1986 |
Restoration of doxorubicin responsiveness in doxorubicin-resistant P388 murine leukaemia cells by dipyrone.
Topics: Aminopyrine; Animals; Dipyrone; DNA; Doxorubicin; Drug Resistance; Drug Synergism; Leukemia P388; Le | 1987 |
Effect of deoxycytidine on the in vitro response of human leukemia cells to inhibitors of de novo pyrimidine biosynthesis.
Topics: 3-Deazauridine; Amides; Aspartic Acid; Cell Division; Cell Line; Deoxycytidine; Deoxycytidine Kinase | 1987 |
Modulation of in vitro response to adriamycin by verapamil in murine P388 leukaemia, Ehrlich ascites carcinoma and sarcoma 180.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; Depression, Chemical; DNA, Neoplasm; Do | 1987 |
[Effect of unithiol and thymidine on the toxic and therapeutic action of adriamycin].
Topics: Animals; Antidotes; Dimercaprol; Doxorubicin; Leukemia, Experimental; Male; Mice; Mice, Inbred C57BL | 1986 |
Schedule-dependent antitumor and toxic effects of thymidine and 5-fluorouracil in AKR and L1210 leukemias.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Female; F | 1986 |
Demonstration of commitment by K562 human erythroleukemia cells.
Topics: Benzidines; Butyrates; Butyric Acid; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; | 1985 |
Differential sensitivity of leukemic cells to growth inhibition by deoxyadenosine and deoxycoformycin.
Topics: Acute Disease; B-Lymphocytes; Cell Line; Cells, Cultured; Coformycin; Deoxyadenine Nucleotides; Deox | 1985 |
New cytotoxic and antitumor agents. VII. Derivatives of 1-benzylidenisoindolin-3-one and 5,6-dihydro-8H-isoquinolo(2,3-a)phthalasin-5-one.
Topics: Adenine; Animals; Antineoplastic Agents; Benzylidene Compounds; Cell Division; Chemical Phenomena; C | 1985 |
Effect of (E)-5-(2-bromovinyl)uracil on the catabolism and antitumor activity of 5-fluorouracil in rats and leukemic mice.
Topics: Animals; Bromouracil; Dihydrouracil Dehydrogenase (NADP); Drug Synergism; Fluorouracil; Leukemia P38 | 1986 |
Inhibition of macromolecular synthesis in P388 mouse leukemia ascites cells by bouvardin (NSC 259968).
Topics: Animals; Antineoplastic Agents, Phytogenic; Depression, Chemical; DNA, Neoplasm; Dose-Response Relat | 1985 |
Cyanopyrazoles as analogs of purine precursors--II. Effects on macromolecular synthesis and cell cycle progression.
Topics: Animals; Antimetabolites, Antineoplastic; Carcinoma, Ehrlich Tumor; Cell Cycle; Cell Line; DNA, Neop | 1985 |
Stimulation of DNA synthesis in vitro in mouse thymic cells by bone marrow preparation.
Topics: Alpha-Globulins; Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Carboxypeptidases; Deoxyr | 1971 |
Isolation and characterization of a herpesvirus from leukemic guinea pigs.
Topics: Animals; Antigens, Viral; Carbon Isotopes; Centrifugation, Density Gradient; Cesium; Chlorides; Cult | 1971 |
Further studies of radiation-induced interphase death of cultured mammalian cells.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Culture Media; Dinitrophenols; Le | 1972 |
Effects of interferon on hemoglobin synthesis and leukemia virus production in Friend cells.
Topics: Animals; Clone Cells; Friend murine leukemia virus; Hemoglobins; Interferons; Kinetics; Leukemia, Ex | 1974 |
Organization and communication in populations of normal and leukemic hemopoietic cells.
Topics: Animals; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; Chromatography, DEAE-Cellulo | 1974 |
Tritiated thymidine uptake by in vitro spleen lymphoid cell cultures following stimulation by GC murine leukemia virus.
Topics: Animals; Cell Count; Cells, Cultured; DNA; DNA, Neoplasm; Lectins; Leukemia Virus, Murine; Leukemia, | 1973 |
Studies on a new mechanism of resistance of L5178Y murine leukemia cells to cytosine arabinoside.
Topics: Animals; Chromosomes; Culture Techniques; Cytarabine; Cytosine Nucleotides; Depression, Chemical; Hy | 1968 |
Induction of leukemia and ovarian tumors in mice by pulse-doses of polycyclic aromatic hydrocarbons.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Benzopyrenes; DNA; Female; Granulosa Cell Tumor; Leukem | 1968 |
Interphase death of cultured mammalian cells (L5178Y).
Topics: Animals; Carbon Isotopes; Cell Division; Cell Line; Culture Techniques; Dactinomycin; Leucine; Leuke | 1969 |
Barbiturate inhibition of growth and of synthesis of deoxyribonucleic acid, ribonucleic acid and protein in cultured mammalian cells.
Topics: Animals; Barbiturates; Cell Line; Clone Cells; DNA, Neoplasm; Leucine; Leukemia, Experimental; Mast- | 1973 |
An inhibitor of cell proliferation released by cultures of macrophages.
Topics: Animals; Antigens, Bacterial; Cell Adhesion; Cell Line; Cell Transformation, Neoplastic; Cells, Cult | 1974 |
Biochemical studies on the nucleic acid metabolism of embryonic tissue and the effect of drugs.
Topics: Animals; Cell Nucleus; Cyclophosphamide; Dactinomycin; Depression, Chemical; DNA; Embryo, Mammalian; | 1968 |
[Susceptibility to inhibition by cyclophosphamide of DNA polymerases in cell nuclei and mitochondria of liver and tumor tissue].
Topics: Animals; Cell Nucleus; Cyclophosphamide; Depression, Chemical; DNA; DNA Nucleotidyltransferases; DNA | 1968 |
[Differenciation of reaction mechanisms of alkylating cytostatics on Ehrlich ascites-carcinoma- and lymphatic leucemic cells].
Topics: Alkylating Agents; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Chlorambucil; Leucine; Leukem | 1970 |
Effect of cycloheximide on regulatory protein for initiating mammalian DNA replication at the nuclear membrane.
Topics: Animals; Antimetabolites; Cell Line; Cell Nucleus; Cells, Cultured; Centrifugation, Density Gradient | 1972 |
Guinea pigs immunized with xenogeneic cells: skin test, in vitro stimulation; cytotoxicity of lymph node cells.
Topics: Animals; Burkitt Lymphoma; Cell Line; Chromium Radioisotopes; Cytotoxicity Tests, Immunologic; DNA; | 1973 |
Inhibition of normal allogeneic responder cells in mouse mixed leukocyte culture by long-passage AKR leukemic lymphoblasts.
Topics: Animals; Cell Line; Female; Leukemia, Experimental; Leukemia, Lymphoid; Lymphocyte Culture Test, Mix | 1974 |
Effect of AC-3579, a diazafluoranthen derivative, on murine leukemia P388 and L1210--I. In vivo study.
Topics: Adenosine Triphosphatases; Animals; Aza Compounds; Fluorenes; Injections, Intraperitoneal; Leukemia | 1973 |
Fluorinated pyrimidines. XXIX. Syntheses of 2',3'-dehydro-5-fluoro-2'-deoxyuridine and 2',3'-dideoxy-5-fluorouridine.
Topics: Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Escherichia coli; Floxuridine; HeLa Ce | 1967 |
Comparative studies of fluorinated pyrimidines with various cell lines.
Topics: Animals; Carcinoma, Hepatocellular; Culture Techniques; Deoxyuridine; Depression, Chemical; DNA, Neo | 1968 |
Deoxycytidine kinase. I. Distribution in normal and neoplastic tissues and interrelationships of deoxycytidine and 1-beta-D-arabinofuranosylcytosine phosphorylation.
Topics: Adenocarcinoma; Animals; Carcinoma, Hepatocellular; Cattle; Chick Embryo; Chromatography, Ion Exchan | 1969 |
Cellular membranes: membrane marker enzyme activities in synchronized mouse leukemic cells L5178Y.
Topics: Animals; Cell Division; Cell Line; Culture Techniques; Endoplasmic Reticulum; Esterases; Leukemia, E | 1970 |
On the characteristics of actinomycin D resistance in L5178Y cells.
Topics: Acid Phosphatase; Animals; Carbon Isotopes; Cell Line; Cell Membrane Permeability; Dactinomycin; Glu | 1970 |
The effect of adenosine 3',5'-monophosphate on ( 3 H)thymidine incorporation in vitro into mouse spleen and thymic cells.
Topics: Adenine Nucleotides; Animals; Bone Marrow; Bone Marrow Cells; Butyrates; Carbon Isotopes; Culture Te | 1971 |
Studies on the relationship of leukemia in animals and man.
Topics: Animals; Burkitt Lymphoma; Cats; Cricetinae; Cytotoxicity Tests, Immunologic; Dogs; Fluorescent Anti | 1971 |
Factors affecting acid phosphatase activity in exponential and synchronized L5178Y mouse leukemia cells.
Topics: Acid Phosphatase; Animals; Bromodeoxyuridine; Cell Fractionation; Cell Line; Cell Nucleus; Dactinomy | 1972 |
Cell cycle changes and the ability of cells to undergo virus-induced fusion.
Topics: Animals; Cell Biology; Cell Division; Cell Fusion; Cell Line; Clone Cells; Cytidine; Demecolcine; Hy | 1972 |
Characterization of guinea pig C-type virus.
Topics: Animals; Cell Line; Cells, Cultured; Guinea Pigs; Kidney; Leukemia, Experimental; Microscopy, Electr | 1973 |
Identification of a critical period during the S phase for activation of the Epstein-Barr virus by 5-iododeoxyuridine.
Topics: Animals; Antigens, Viral; Cell Line; DNA, Neoplasm; Herpesvirus 4, Human; Humans; Idoxuridine; Leuke | 1973 |
Cell kinetics of virally-induced leukemias.
Topics: Animals; Autoradiography; Avian Leukosis Virus; Bone Marrow Examination; Carbon Radioisotopes; Cell | 1973 |
[Hemopoietic stem cells in murine viurs-induced leukemia. I. Spleen colony assays in CBA mice after Rauscher virus infection (author's transl)].
Topics: Anemia; Animals; Blood Cell Count; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; | 1973 |
Induction of lymphocyte-mediated cytotoxicity against allogeneic tumor cells by concanavalin A in vivo.
Topics: Animals; Binding Sites, Antibody; Cell Division; Cell Membrane; Concanavalin A; Cytotoxicity Tests, | 1974 |
Stem cell kinetics in the L 5222 rat leukemia.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cell Count; Cell Division; Erythropoiesis; Female; Iron Rad | 1974 |
Colony forming unit suicide in normal and Rauscher leukemic mice given tritiated thymidine in vivo.
Topics: Animals; Cell Division; Cell Survival; Clone Cells; Depression, Chemical; Female; Hematopoiesis; Leu | 1974 |
Cellular differentiation in a murine myelomonocytic leukemia.
Topics: Animals; Antibodies; Ascitic Fluid; Binding Sites; Bone Marrow; Bone Marrow Cells; Candida; Cell Adh | 1972 |
Action of 5-bromodeoxyuridine on the induction of haemoglobin synthesis in mouse leukaemia cells resistant to 5-BUdR.
Topics: Animals; Bromodeoxyuridine; Carbon Isotopes; Cell Line; Clone Cells; Dimethyl Sulfoxide; DNA, Neopla | 1973 |
Proliferation, survival and malignancy of chloroleukaemia cells grown in diffusion chambers in vivo.
Topics: Animals; Autoradiography; Cell Aggregation; Cell Count; Cell Division; Cell Survival; Cells, Culture | 1972 |
Effects of the antineoplastic alkaloid acronycine on nucleoside uptake and incorporation into nucleic acids by cultured L5178Y cells.
Topics: Acridines; Alkaloids; Animals; Antineoplastic Agents; Carbon Radioisotopes; Cell Line; Cell-Free Sys | 1973 |
Effect of the acute rat leukemia L5222 on bone marrow stroma cells.
Topics: Animals; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Count; Endothelium; Female; Hematopoi | 1974 |
Hemoglobin biosynthesis in murine virus-induced leukemia cells in vitro.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Dimethyl Sulfoxide; Dimethyl | 1974 |
Protection of DNA molecules of cultured mammalian cells from radiation-induced single-strand scissions by various alcohols and SH compounds.
Topics: Alcohols; Animals; Butanols; Carbon Isotopes; Cell Line; Cells, Cultured; Centrifugation, Density Gr | 1972 |
Effects of BUdR-labelling on radiation-induced DNA breakage and subsequent rejoining in cultured mammalian cells.
Topics: Animals; Bromodeoxyuridine; Carbon Isotopes; Cells, Cultured; Centrifugation, Density Gradient; Cyto | 1972 |
Changes in the deoxyribonucleoside triphosphate pools of mouse 5178Y lymphoma cells following exposure to methotrexate or 5-fluorouracil.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cells, Cultured; Deoxyadenosines; Deoxycytidine; Deoxyri | 1973 |
L2C Guinea pig lymphatic leukemia: a "B" cell leukemia.
Topics: Animals; Antibody Formation; Binding Sites; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cells, | 1972 |
Heterologous antiserum to thymus-derived cells in the guinea-pig.
Topics: Animals; Antibody Formation; Antigen-Antibody Reactions; Antigens; Chromium Isotopes; Cytotoxicity T | 1972 |
The role of the phagocyte in host-parasite interactions. XXXIV. The effect of phagocytizable particles and phytohemmagglutinin-P on DNA synthesis by spleen cells from leukemic and non-leukemic AKR mice.
Topics: Age Factors; Animals; DNA; Escherichia coli; Lectins; Leukemia, Experimental; Leukocyte Count; Metho | 1972 |
Leukemia virus-induced immunosuppression. IX. Depression of delayed hypersensitivity and MIF production after infection of mice with Friend leukemia virus.
Topics: Animals; Cell Migration Inhibition; Concanavalin A; Female; Freund's Adjuvant; Friend murine leukemi | 1973 |
Alloantiserum-induced inhibition of immune response gene product function. I. Cellular distribution of target antigens.
Topics: Absorption; Animals; Antibody Formation; Ascitic Fluid; Cell Line; Chromium Radioisotopes; Cytologic | 1974 |
An automatic synchronizer for suspension culture of L5178Y cells.
Topics: Animals; Cell Division; Cell Line; Cells, Cultured; Colchicine; Cytological Techniques; Leukemia, Ex | 1974 |
[Cellular cycle of transplantable leukemia L 1210].
Topics: Animals; Ascitic Fluid; Autoradiography; Cell Count; Cell Division; Cell Survival; Cell Transformati | 1973 |
Relation between replicating DNA and nuclear membrane in L5178Y leukemia cells.
Topics: Animals; Autoradiography; Carbon Isotopes; Cell Line; Cell Nucleus; Centrifugation, Density Gradient | 1972 |
Antineoplastic drug activity in the mitotic cycle--effects of six agents on macromolecular synthesis in synchronous mammalian leukemic cells.
Topics: Animals; Antineoplastic Agents; Asparaginase; Azaserine; Camptothecin; Culture Media; DNA, Neoplasm; | 1972 |
[Radiation-induced adsorption of 3 H-thymidine on leukoma cells].
Topics: Animals; Cell Membrane Permeability; Leukemia; Leukemia, Experimental; Neoplasm Transplantation; Rat | 1973 |
Thymus function in spontaneous lymphoid leukemia. II. In vitro response of "preleukemic" and leukemic thymus cells to mitogens.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Concanavalin A; Female; Lectins; Leukemia, | 1973 |
Effects of phenylalanine amonia-lyase and phenylalanine deprivation on murine leukemic lymphoblasts in vitro.
Topics: Ammonia-Lyases; Animals; Cells, Cultured; DNA, Neoplasm; Leucine; Leukemia, Experimental; Lymphocyte | 1973 |
Polyamine content of AKR leukemic cells in relation to the cell cycle.
Topics: Animals; Cell Division; Cell Separation; Chromatography, Thin Layer; Female; Fluorometry; Leukemia, | 1973 |
Effect of phosphorylated cyclocytidine on deoxyribonucleic acid polymerase.
Topics: Anhydrides; Animals; Antineoplastic Agents; Carbon Radioisotopes; Cytarabine; Cytosine Nucleotides; | 1973 |
Growth of the P388 leukemia as an ascites tumor in zinc-deficient mice.
Topics: Animals; Cell Division; Deficiency Diseases; DNA, Neoplasm; Leukemia, Experimental; Leukemia, Lympho | 1973 |
The behaviour of resting bone marrow cells in rats with acute leukaemia.
Topics: Animals; Blood Cell Count; Blood Platelets; Bone Marrow; Bone Marrow Cells; Cell Division; Erythrocy | 1973 |
Studies on erythroid differentiation of Friend virus-induced murine leukemic cells.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cells, Cultured; Dimethyl Sulfoxide; DNA; Erythroc | 1973 |
Study of the cellular proliferation kinetics of Friend leukemia.
Topics: Animals; Autoradiography; Cell Nucleus; Cell Survival; Cell Transformation, Neoplastic; Erythrocytes | 1973 |
DNA replication and the nuclear envelope.
Topics: Animals; Carbon Radioisotopes; Cell Division; Cell Line; Cell Nucleus; Centrifugation, Density Gradi | 1973 |
[Early changes in cellular DNA during exposure to leukemic cell RNA and Rauscher leukemogenic virus].
Topics: Animals; Autoradiography; Cell Transformation, Neoplastic; Cells, Cultured; DNA; In Vitro Techniques | 1974 |
Distinction between inhibition of purine nucleotide synthesis and the delayed cytotoxic reaction of 6-mercaptopurine.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Inosine; Leukemia, Experimental; Leukemia, Lymphoi | 1974 |
Studies on the mechanism of resistance to lymphocytolysis induced by corticosteroids.
Topics: Animals; Carnitine; Cell Line; Cell Nucleus; Drug Resistance; Fatty Acids, Nonesterified; Glucose; H | 1974 |
[Effect of E. coli-L-asparaginase on the nucleic acid metabolism of lymphatic bovine leukemia cells].
Topics: Animals; Asparaginase; Carbon Isotopes; Cattle; Cell Line; Culture Techniques; Depression, Chemical; | 1969 |
Light-induced cross-linking of DNA in the presence of a furocoumarin (psoralen). Studies with phage lambda, Escherichia coli, and mouse leukemia cells.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Chromatography; Coliphages; Coumarins; Culture | 1970 |
Inhibition of protein synthesis in Escherichia coli and L5178Y mouse leukemic cells by phenylalanine and tryptophan.
Topics: Animals; Bacterial Proteins; Cell Line; Culture Techniques; DNA; Escherichia coli; Glucosamine; Glyc | 1971 |
Studies on the antitumor activity, mechanism of action, and cell cycle effects of camptothecin.
Topics: Alkaloids; Animals; Antineoplastic Agents; Autoradiography; Carbon Isotopes; Cell Transformation, Ne | 1971 |
Purineless death as a link between growth rate and cytotoxicity by methotrexate.
Topics: Animals; Cells, Cultured; Depression, Chemical; DNA, Neoplasm; Hypoxanthines; In Vitro Techniques; L | 1972 |
Lymphoid-cell renewal under low-level irradiation. XI. The cell cycle and growth kinetics during radiation leukemogenesis in C57BL mice.
Topics: Animals; Autoradiography; Cell Differentiation; Cell Division; DNA, Neoplasm; Kinetics; Leukemia, Ex | 1972 |
Studies of inhibition of tumour cell DNA synthesis by immune cells in Gross virus induced leukemia.
Topics: Adjuvants, Immunologic; AKR murine leukemia virus; Animals; Antigens, Neoplasm; Cells, Cultured; DNA | 1972 |
Role of catabolism in pyrimidine utilization for nucleic acid synthesis in vivo.
Topics: Animals; Azo Compounds; Dactinomycin; Depression, Chemical; DNA; DNA, Neoplasm; Fluorouracil; Intest | 1972 |
Inhibition of RNA, DNA and protein synthesis by antisera in mouse leukemic cells L5178YR.
Topics: Animals; Carbon Isotopes; Cell Line; Cells, Cultured; Complement System Proteins; Culture Media; DNA | 1972 |
Camptothecin effects on DNA synthesis in murine leukemia cells.
Topics: Alkaloids; Animals; Antineoplastic Agents; Carbon Isotopes; Cell Division; Cell Line; Cells, Culture | 1972 |
Actinomycin D induction of acid phosphatase in synchronized L5178Y mouse leukemia cells.
Topics: Acid Phosphatase; Animals; Cell Count; Cell Line; Colchicine; Dactinomycin; Daunorubicin; DNA Replic | 1972 |
Characterization of the rapidly labeled hybridizable RNA synthesized in L5178Y mouse leukemic cells. Hybridization lifetime studies.
Topics: Animals; Cell Line; Centrifugation, Density Gradient; Dactinomycin; DNA, Neoplasm; Filtration; Half- | 1971 |
Evaluation of cell damage in immune reactions by release of radioactivity from 3 H-uridine labeled cells.
Topics: Animals; Complement System Proteins; Cytotoxicity Tests, Immunologic; Guinea Pigs; Immune Sera; In V | 1971 |
DNA synthesis time in leukaemic cells as measured by the double labelling and the percentage labelled mitoses methods.
Topics: Aged; Animals; Autoradiography; Carbon Isotopes; Cell Count; Cells; Computers; DNA, Neoplasm; Humans | 1971 |
Anticancer effects of propanals: comparison between human and animal tumor systems.
Topics: Aldehydes; Animals; Antineoplastic Agents; Carbohydrate Metabolism; Carbon Isotopes; DNA, Neoplasm; | 1971 |
Viral leukemia: increased thymidine assimilation.
Topics: Animals; Cell Transformation, Neoplastic; DNA; Female; Friend murine leukemia virus; Leukemia, Exper | 1971 |
Specific vulnerability of the largest telocentric chromosome of rat bone marrow cells to 7,12-dimethylbenz[a]anthracene.
Topics: Animals; Autoradiography; Benz(a)Anthracenes; Bone Marrow; Bone Marrow Cells; Child; Chromosome Aber | 1971 |
5-Diazo-4-oxo-L-norvaline: reactive asparagine analog with biological specificity.
Topics: Amino Acids; Animals; Antineoplastic Agents; Asparaginase; Asparagine; Carbon Isotopes; Culture Tech | 1968 |
Growth rate and cell kill.
Topics: Animals; Cell Division; Cell Survival; Cells, Cultured; Deoxyuridine; DNA, Neoplasm; Drug Interactio | 1971 |
Continuous irradiation of a murine lymphoma line P388F in vitro.
Topics: Animals; Autoradiography; Cell Division; Culture Techniques; DNA; Leukemia, Experimental; Leukemia, | 1966 |
Inhibition of growth of leukemia cells by enzymic folate depletion.
Topics: Animals; Carboxypeptidases; Carcinoma 256, Walker; Cell Line; Culture Media; Depression, Chemical; F | 1971 |
Metabolism of uracil and 5-fluorouracil in P388 murine leukemia cells.
Topics: Animals; Carbon Isotopes; Cell Line; Cell-Free System; Culture Techniques; Fluorouracil; Leukemia, E | 1969 |
S-phase cells of rapidly growing and resting populations. Differences in response to methotrexate.
Topics: Animals; Cell Line; Clone Cells; Culture Techniques; Deoxyuridine; DNA; Folic Acid Antagonists; Kine | 1969 |
The rationale of the chemotherapeutic regimes relative to present knowledge of cell and population kinetics.
Topics: Animals; Cell Differentiation; Cell Division; DNA; Humans; Kinetics; Leukemia; Leukemia L1210; Leuke | 1970 |
Thymidine kinase as a determinant of the response to 5-fluoro-2'-deoxyuridine in transplantable murine leukemias.
Topics: Animals; Carbon Isotopes; Culture Techniques; Deoxyuridine; Fluorine; Leukemia, Experimental; Mice; | 1970 |
Glycosidase activity. Glycosidase acitivity in L5178Y mouse leukemic cells and the activity of acid phosphatase, beta-galactosidase and beta-N-acetylgalactosaminidase and beta-N-acetylglucosaminidase in a synchronous L5178Y cell population.
Topics: Acid Phosphatase; Animals; Cell Line; Culture Techniques; Galactosidases; Glucosidases; Glucuronidas | 1970 |
Killing of cultured mammalian cells by radioactive decay of tritiated thymidine at -196 degrees C.
Topics: Animals; Autoradiography; Cell Line; Culture Techniques; DNA; Freezing; Leukemia, Experimental; Math | 1970 |
Fluorinated pyrimidines. XXXVII. Effects of 5-trifluoromethyl-2'-deoxyuridine on the synthesis of deoxyribonucleic acid of mammalian cells in culture.
Topics: Animals; Bromine; Carbon Isotopes; Cell Division; Cell Line; Centrifugation, Density Gradient; Cesiu | 1970 |
Sensitivity to L-asparaginase and amino acid metabolism.
Topics: Amino Acids; Animals; Asparaginase; Asparagine; Carbon Isotopes; Carcinoma 256, Walker; Citrulline; | 1970 |
Warfarin and vitamin K accelerate protein and glycoprotein synthesis in isolated rat liver mitochondria in vitro.
Topics: Animals; Brain; Carbon Isotopes; Cell Fractionation; Chloramphenicol; Culture Techniques; Cyclohexim | 1970 |
Cysteamine, cystamine, and single-strand breaks of DNA in cultured mammalian cells.
Topics: Animals; Carbon Isotopes; Cell Line; Centrifugation, Density Gradient; Culture Techniques; Cystamine | 1970 |
Proliferation of macrophage and granulocyte precursors in response to primary and transplanted tumors.
Topics: Animals; Bone Marrow; Femur; In Vitro Techniques; Leukemia, Experimental; Leukemia, Lymphoid; Leukoc | 1971 |
[Effect of hydrocortisone on the life cycle of cells of spontaneous lymphatic leukemia in mice].
Topics: Animals; DNA Replication; DNA, Neoplasm; Hydrocortisone; Leukemia, Experimental; Leukemia, Lymphoid; | 1967 |
[Disturbances in the life cycle of leukemic cells by N-nitrosopropylurea].
Topics: Animals; DNA, Neoplasm; Leukemia, Experimental; Mice; Mitosis; Nitroso Compounds; Thymidine; Tritium | 1967 |
Antigenic modulation. Loss of TL antigen from cells exposed to TL antibody. Study of the phenomenon in vitro.
Topics: Amides; Animals; Antigen-Antibody Reactions; Antigens; Dactinomycin; Immune Sera; In Vitro Technique | 1968 |
Antitumor activity and some pharmacologic properties of anthramycin methyl ether.
Topics: Animals; Antibiotics, Antineoplastic; Blood Pressure; Culture Techniques; Dactinomycin; DNA; Dogs; E | 1968 |
Anthramycin, a new type of DNA-inhibiting antibiotic: reaction with DNA and effect on nucleic acid synthesis in mouse leukemia cells.
Topics: Animals; Antibiotics, Antineoplastic; Carbon Isotopes; Cattle; Centrifugation, Density Gradient; Che | 1968 |
Effects of cytosine arabinoside on the cell viability and uptake of deoxypyrimidine nucleosides in L5178Y cells.
Topics: Animals; Culture Techniques; Cytarabine; Depression, Chemical; DNA, Neoplasm; Leukemia, Experimental | 1968 |
Interaction of mouse leukemic cells with L cells in tissue culture. I. Passage of leukemic cell DNA into the nuclei of L cells.
Topics: Animals; Autoradiography; Cell Nucleolus; Cell Nucleus; Deoxyribonucleases; DNA; L Cells; Leukemia, | 1968 |
Interaction of mouse leukemic cells with L cells i n tissue culture. II. Fusion of leukemic and L cell nuclei.
Topics: Animals; Autoradiography; Cell Nucleus; Cytogenetics; Hybridization, Genetic; L Cells; Leukemia, Exp | 1968 |
Deoxyribonucleic acid synthesis during the first postirradiation life cycle of lethally irradiated cultured mammalian cells (L5178Y).
Topics: Animals; Autoradiography; Carbon Isotopes; Culture Techniques; DNA, Neoplasm; Hydrogen; Leukemia, Ex | 1968 |
On the poor correlation between the inhibition by methotrexate of dihydrofolate reductase and of deoxynucleoside incorporation into DNA.
Topics: Animals; Deoxyuridine; DNA, Neoplasm; Folic Acid Antagonists; In Vitro Techniques; Leukemia L1210; L | 1968 |
Replicating units (replicons) of DNA in cultured mammalian cells.
Topics: Animals; Bromodeoxyuridine; Centrifugation, Density Gradient; Culture Techniques; DNA Replication; L | 1968 |
Effective specific activity dilution in labeled DNA of cultured mammalian cells (L5178Y).
Topics: Animals; Carbon Isotopes; Culture Techniques; DNA; Leukemia, Experimental; Mice; Thymidine; Time Fac | 1969 |
Radiation-induced breaks of DNA in cultured mammalian cells.
Topics: Animals; Carbon Isotopes; Centrifugation, Density Gradient; Culture Techniques; DNA, Neoplasm; Hydro | 1969 |
Nucleic acids. X. Enzymatic hydrolysis of dinucleoside phosphates containing ara-cytidine (cytarabine).
Topics: Animals; Antiviral Agents; Carcinoma, Squamous Cell; Cytarabine; Esterases; Esters; Humans; Kidney; | 1969 |
Radiation-induced mitotic delay in cultured mammalian cells (L5178Y).
Topics: Animals; Culture Techniques; Dactinomycin; DNA; Leucine; Leukemia, Experimental; Leukocytes; Mice; M | 1969 |
Accumulation of two alkylating agents, nitrogen mustard and busulfan, by murine leukemia cells in vitro.
Topics: Amines; Animals; Busulfan; In Vitro Techniques; Leukemia L1210; Leukemia, Experimental; Mechloretham | 1969 |
Study on the effect of dibromodulcitol (1,6-dibromo-1,6-dideoxydulcitol) on the desoxy-ribonucleic acid metabolism of NK-Ly ascites tumour cells with an autoradiographic method.
Topics: Alcohols; Animals; Antineoplastic Agents; Ascites; Autoradiography; Depression, Chemical; DNA, Neopl | 1969 |
RNA components and ribonuclease activity of hemic tissues.
Topics: Animals; Bone Marrow; Carbon Isotopes; Culture Techniques; Enzymes; Leukemia, Experimental; Liver; M | 1965 |
Inhibition of the biosynthesis of thymidylic acid by 4-N-Hydroxy-2'-deoxycytidine in L5178Y leukemic cells.
Topics: Animals; Carbon Isotopes; Culture Techniques; Deoxyuridine; DNA, Neoplasm; Leukemia, Experimental; M | 1966 |
Biochemical mechanisms of drug resistance. 3. Differences in the metabolism of mouse leukaemic cells sensitive and resistant to 5-azacytidine.
Topics: Animals; Carbon Isotopes; Leukemia, Experimental; Ligases; Mice; Nitrogen; Nucleosides; RNA, Neoplas | 1966 |