Page last updated: 2024-11-06

thymidine and Disease Models, Animal

thymidine has been researched along with Disease Models, Animal in 180 studies

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Treatment of the acute disease with N-methanocarbathymidine significantly reduced the severity of acute disease and decreased acute vaginal virus shedding more effectively than acyclovir."7.81Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs. ( Bernstein, DI; Bravo, FJ; Cardin, RD; Glazer, RI; Pullum, DA; Rahman, A; Shen, H; Wang, M, 2015)
"The outcome of neonatal herpes simplex (HSV) infection, even after therapy with high dose acyclovir (ACV), is not optimum."7.77N-Methanocarbathymidine is more effective than acyclovir for treating neonatal herpes simplex virus infection in guinea pigs. ( Bernstein, DI; Bravo, FJ; Cardin, RD; Clark, JR; Earwood, JD; Glazer, R; Rahman, A, 2011)
"N-methanocarbathymidine (N-MCT) has previously been shown to be effective against lethal orthopoxvirus and herpes simplex virus type-1 infections in mice."7.77Efficacy of orally administered low dose N-methanocarbathymidine against lethal herpes simplex virus type-2 infections of mice. ( Collins, DJ; Glazer, R; Quenelle, DC; Rahman, A; Rice, TL, 2011)
"The proliferative activity of the lens epithelium in the early stages of cataract crisis was investigated in rats and mice using the 3H-thymidine autoradiographic method with the whole-mount preparations of total lens epithelial cells."7.68Proliferative changes of lens epithelial cells in rat and mouse galactose cataracts--examination using whole-mount preparations. ( Akagi, Y; Ikebe, H; Okamoto, S; Terubayashi, H; Tsuji, T, 1993)
"The inherited disease Lesch-Nyhan syndrome, which is caused by a deficiency of the enzyme hypoxanthine phosphoribosyltransferase (HPRT), is characterized by behavioural alterations, including self-injurious behaviour and mental retardation."7.68Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice. ( Melton, DW; Wu, CL, 1993)
"An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days."7.66Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979)
" The Phase I clinical study demonstrated that end-of-treatment virological response rates were better for telbivudine recipients at multiple dosing levels as compared with placebo patients."6.43Telbivudine: a new nucleoside analogue for the treatment of chronic hepatitis B. ( Han, SH, 2005)
"Telbivudine (LdT) is an anti-hepatitis B virus (HBV) drug that has been found to steadily improve renal function, but the mechanism of drug action is unclear."5.48Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling. ( Chen, J; Li, D, 2018)
"The sertraline-treated rats showed a significant reduction in clinical arthritis compared to controls, at all doses given, accompanied by a significant increase in interleukin 10 and a decrease in tumor necrosis factor-α levels and cycloxygenase-2 production, without lymphotoxicity."5.38Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis. ( Baharav, E; Bar, M; Gil-Ad, I; Karp, L; Taler, M; Weinberger, A; Weizman, A, 2012)
"Azaindole-1 treatment resulted in a decreased immunoreactivity for phospho-myosin phosphatase target subunit 1 and proliferating cell nuclear antigen in pulmonary vessels of MCT-injected rats, suggesting an impaired ROCK activity and reduced proliferating cells."5.36Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension. ( Dahal, BK; Ghofrani, HA; Grimminger, F; Kast, R; Kosanovic, D; Lai, YJ; Pamarthi, PK; Schermuly, RT; Schirok, H; Seeger, W; Stasch, JP; Sydykov, A; Weissmann, N, 2010)
"Albendazole treatment (300 mg/kg per day oral for 20 days) of nude mice inoculated subcutaneously with SKHEP-1, led to profound suppression of tumor growth."5.31In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. ( Akhter, J; Almajd, R; Bowery, P; Morris, DL; Pourgholami, MH; Woon, L, 2001)
" The methylation of phosphatidylethanolamine to form choline has been extensively studied in the context of fatty liver disease."3.96Disruption of hepatic one-carbon metabolism impairs mitochondrial function and enhances macrophage activity in methionine-choline-deficient mice. ( da Silva, RP; Eudy, BJ; Fernandez, G; Lai, J; Mathews, CE; McDermott, CE, 2020)
"Treatment of the acute disease with N-methanocarbathymidine significantly reduced the severity of acute disease and decreased acute vaginal virus shedding more effectively than acyclovir."3.81Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs. ( Bernstein, DI; Bravo, FJ; Cardin, RD; Glazer, RI; Pullum, DA; Rahman, A; Shen, H; Wang, M, 2015)
"In this study, we investigated the effects of 2,2'-dithienyl diselenide (DTDS), an organoselenium compound, against seizures induced by kainic acid (KA) in rats."3.77Protective effect of 2,2'-dithienyl diselenide on kainic acid-induced neurotoxicity in rat hippocampus. ( Bortolatto, CF; Jesse, CR; Nogueira, CW; Rambo, LM; Ribeiro, LR; Roman, SS; Royes, LF; Wilhelm, EA, 2011)
"The outcome of neonatal herpes simplex (HSV) infection, even after therapy with high dose acyclovir (ACV), is not optimum."3.77N-Methanocarbathymidine is more effective than acyclovir for treating neonatal herpes simplex virus infection in guinea pigs. ( Bernstein, DI; Bravo, FJ; Cardin, RD; Clark, JR; Earwood, JD; Glazer, R; Rahman, A, 2011)
"N-methanocarbathymidine (N-MCT) has previously been shown to be effective against lethal orthopoxvirus and herpes simplex virus type-1 infections in mice."3.77Efficacy of orally administered low dose N-methanocarbathymidine against lethal herpes simplex virus type-2 infections of mice. ( Collins, DJ; Glazer, R; Quenelle, DC; Rahman, A; Rice, TL, 2011)
"The effects of vasoactive intestinal peptide (VIP) antagonists on breast cancer cells were investigated."3.71VIP receptor antagonists and chemotherapeutic drugs inhibit the growth of breast cancer cells. ( Brenneman, DC; Chan, D; Fridkin, M; Gelber, E; Gozes, I; Levy, A; Leyton, J; Moody, TW, 2001)
"The proliferative activity of the lens epithelium in the early stages of cataract crisis was investigated in rats and mice using the 3H-thymidine autoradiographic method with the whole-mount preparations of total lens epithelial cells."3.68Proliferative changes of lens epithelial cells in rat and mouse galactose cataracts--examination using whole-mount preparations. ( Akagi, Y; Ikebe, H; Okamoto, S; Terubayashi, H; Tsuji, T, 1993)
"The inherited disease Lesch-Nyhan syndrome, which is caused by a deficiency of the enzyme hypoxanthine phosphoribosyltransferase (HPRT), is characterized by behavioural alterations, including self-injurious behaviour and mental retardation."3.68Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice. ( Melton, DW; Wu, CL, 1993)
"An experimental model of pulmonary fibrosis has been developed by dosing rats with one-fifth the LD50 dose of the herbicide paraquat on 5 consecutive days."3.66Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat. ( Griffin, M; Smith, LL; Wynne, J, 1979)
" Ovalbumin-presensitized Praomys (Mastomys) natalensis were challenged in the gastric wall with ovalbumin and a gastric ulcer developed at the challenge site 3 days later as a result of a mucosal anaphylactic reaction."3.66Measurement of glycoprotein content and cell kinetics in preulcerous gastric mucosa. ( Andre, C; Andre, F; Fournier, S, 1979)
" The Phase I clinical study demonstrated that end-of-treatment virological response rates were better for telbivudine recipients at multiple dosing levels as compared with placebo patients."2.43Telbivudine: a new nucleoside analogue for the treatment of chronic hepatitis B. ( Han, SH, 2005)
"Telbivudine (LdT) is an anti-hepatitis B virus (HBV) drug that has been found to steadily improve renal function, but the mechanism of drug action is unclear."1.48Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling. ( Chen, J; Li, D, 2018)
"Here we show that experimental autoimmune encephalomyelitis (EAE) is ameliorated with markedly reduced induction of antigen-specific Th1 and Th17 cells in CD30 knockout mice."1.43Requirement of CD30 expression on CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis. ( Kira, J; Oyamada, A; Shinoda, K; Sun, X; Yamada, H; Yoshikai, Y, 2016)
"TK1 was responsible for anticancer activity of dT-QX while levels of TYMP counteracted such an activity."1.42Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways. ( Liu, H; Wei, Q; Zhang, D; Zhang, Z; Zhou, H; Zhou, Q, 2015)
"[(18)F]-FLT-PET was conducted in human cancer xenograft-bearing mice."1.39Limits of [18F]-FLT PET as a biomarker of proliferation in oncology. ( Ayers, GD; Coffey, RJ; Manning, HC; McKinley, ET; Saleh, SA; Smith, RA; Washington, MK; Zhao, P, 2013)
"The sertraline-treated rats showed a significant reduction in clinical arthritis compared to controls, at all doses given, accompanied by a significant increase in interleukin 10 and a decrease in tumor necrosis factor-α levels and cycloxygenase-2 production, without lymphotoxicity."1.38Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis. ( Baharav, E; Bar, M; Gil-Ad, I; Karp, L; Taler, M; Weinberger, A; Weizman, A, 2012)
"Mice were immunized to induce experimental autoimmune encephalomyelitis (EAE) and treated with AP for seven days during different phases of disease."1.38Endotoxin- and ATP-neutralizing activity of alkaline phosphatase as a strategy to limit neuroinflammation. ( Boonstra, JG; Brands, R; Hintzen, RQ; Huizinga, R; Kreft, KL; Laman, JD; Onderwater, S, 2012)
"data indicate that seizures lead to a loss and alteration of Purkinje cells in the cerebellum of immature rats."1.37A single episode of neonatal seizures alters the cerebellum of immature rats. ( Lomoio, S; Mares, V; Necchi, D; Scherini, E, 2011)
"Azaindole-1 treatment resulted in a decreased immunoreactivity for phospho-myosin phosphatase target subunit 1 and proliferating cell nuclear antigen in pulmonary vessels of MCT-injected rats, suggesting an impaired ROCK activity and reduced proliferating cells."1.36Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension. ( Dahal, BK; Ghofrani, HA; Grimminger, F; Kast, R; Kosanovic, D; Lai, YJ; Pamarthi, PK; Schermuly, RT; Schirok, H; Seeger, W; Stasch, JP; Sydykov, A; Weissmann, N, 2010)
"Postangioplasty and in-stent restenosis remain ominous problems in percutaneous coronary intervention where good animal models of restenosis proneness and resistance are needed."1.35The critical role of the intrinsic VSMC proliferation and death programs in injury-induced neointimal hyperplasia. ( Brandon, JL; Brock, TA; Doan, D; Felix, K; Fujise, K; Mnjoyan, ZH; Rege, AA; Sitter, CL, 2008)
"The blockade of 5-LOX inhibits colon cancer cell proliferation both in vitro and in vivo and may prove a beneficial chemopreventive therapy in colon cancer."1.35Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model. ( Adrian, TA; Bell, RH; Bentrem, DJ; Ding, XZ; Kennedy, TJ; Melstrom, LG; Rao, SM; Salabat, MR; Strouch, M; Talamonti, MS; Ternent, CA; Witt, RC, 2008)
"The role of MMPs in the development of multiple myeloma is poorly understood."1.32Multifunctional role of matrix metalloproteinases in multiple myeloma: a study in the 5T2MM mouse model. ( Asosingh, K; Blacher, S; Carron, C; Croucher, PI; De Bruyne, E; De Leenheer, E; De Raeve, H; Devy, L; Noël, A; Van Camp, B; Van Riet, I; Van Valckenborgh, E; Vanderkerken, K, 2004)
"Albendazole treatment (300 mg/kg per day oral for 20 days) of nude mice inoculated subcutaneously with SKHEP-1, led to profound suppression of tumor growth."1.31In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole. ( Akhter, J; Almajd, R; Bowery, P; Morris, DL; Pourgholami, MH; Woon, L, 2001)
"Adoptive transfer experimental autoimmune encephalomyelitis (AT-EAE), a disease resembling multiple sclerosis, is induced in rats by myelin basic protein (MBP)-activated CD4(+) T lymphocytes."1.31Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis. ( Barbaria, J; Beeton, C; Béraud, E; Bernard, D; Cahalan, MD; Chandy, KG; Clot-Faybesse, O; Pennington, M; Wulff, H, 2001)
"Hypercholesterolemia was associated to a significant decrease in mean platelet volume and bleeding time, but it did not affect the proliferative effect of serum and platelet lysates nor its growth factor content."1.29[Growth factors and mitogenic activity in experimental hypercholesterolemia]. ( Alegría, E; García Bolao, I; Gil, MJ; Grau, A; Martínez, A; Martínez-Caro, D; Merino, J, 1996)
"Hepatic granulomas were formed in the osteopetrotic mice by glucan injection without a supply of blood monocytes."1.29The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor. ( Naito, M; Shultz, LD; Takahashi, K; Umeda, S, 1994)
"Because osteoarthritis is a focal disease, histologic controls were used to measure the severity in different areas of the cartilage and in different specimens."1.27Degradative enzyme systems in osteoarthritic cartilage. ( Ehrlich, MG, 1985)
"The trifluridine was used as 1% eyedrops, whereas bromovinyldeoxyuridine was used as either 0."1.26Experimental stroma herpes simplex keratitis. Influence of treatment with topical bromovinyldeoxyuridine and trifluridine. ( De Clercq, E; Descamps, J; Maudgal, PC; Missotten, L; Wijnhoven, J, 1982)

Research

Studies (180)

TimeframeStudies, this research(%)All Research%
pre-199081 (45.00)18.7374
1990's32 (17.78)18.2507
2000's31 (17.22)29.6817
2010's33 (18.33)24.3611
2020's3 (1.67)2.80

Authors

AuthorsStudies
Suzuki, M1
Matsuda, T1
Nakajima, K1
Yokouchi, Y1
Kuge, Y1
Ogawa, M2
Liu, Z1
Chen, S1
Shan, H1
Jia, Y1
Chen, M1
Song, Y1
Lai, L1
Li, Z1
Eudy, BJ1
McDermott, CE1
Fernandez, G1
Mathews, CE1
Lai, J1
da Silva, RP1
Lopez-Gomez, C1
Levy, RJ1
Sanchez-Quintero, MJ1
Juanola-Falgarona, M1
Barca, E2
Garcia-Diaz, B2
Tadesse, S1
Garone, C2
Hirano, M3
Chen, J1
Li, D1
Lin, L2
Ge-Er, L1
Fang-Zhou, Y1
Bao-Chang, C1
Chunqin, M1
Tu-Lin, L1
De, J1
Castelli, A1
Susani, L1
Menale, C1
Muggeo, S1
Caldana, E1
Strina, D1
Cassani, B1
Recordati, C1
Scanziani, E1
Ficara, F1
Villa, A1
Vezzoni, P1
Paulis, M1
Guillermier, C1
Doherty, SP1
Whitney, AG1
Babaev, VR1
Linton, MF1
Steinhauser, ML1
Brown, JD1
McKinley, ET1
Ayers, GD1
Smith, RA1
Saleh, SA1
Zhao, P1
Washington, MK1
Coffey, RJ1
Manning, HC1
Sun, Y1
Evans, J1
Russell, B1
Kydd, R1
Connor, B1
Fischer, MA1
Smith, JL1
Shum, D1
Stein, DA1
Parkins, C1
Bhinder, B1
Radu, C1
Hirsch, AJ1
Djaballah, H1
Nelson, JA1
Früh, K1
Leung, KY1
De Castro, SC1
Savery, D1
Copp, AJ1
Greene, ND1
Torres-Torronteras, J1
Viscomi, C1
Cabrera-Pérez, R1
Cámara, Y1
Di Meo, I1
Barquinero, J1
Auricchio, A1
Pizzorno, G2
Zeviani, M1
Martí, R1
Mojahed, H1
Gutierrez, P1
Tanji, K1
Arias-Mendoza, F1
Quinzii, CM1
Herrera, VL1
Pasion, KA1
Moran, AM1
Zaninello, R1
Ortu, MF1
Fresu, G1
Piras, DA1
Argiolas, G1
Troffa, C1
Glorioso, V1
Masala, W1
Glorioso, N1
Ruiz-Opazo, N1
Martiniova, L1
Field, MS1
Finkelstein, JL1
Perry, CA1
Stover, PJ1
Wei, Q1
Liu, H1
Zhou, H1
Zhang, D1
Zhang, Z1
Zhou, Q1
Bernstein, DI2
Bravo, FJ2
Pullum, DA1
Shen, H1
Wang, M1
Rahman, A3
Glazer, RI1
Cardin, RD2
Kriegeskorte, A1
Lorè, NI1
Bragonzi, A1
Riva, C1
Kelkenberg, M1
Becker, K1
Proctor, RA1
Peters, G1
Kahl, BC1
Shinoda, K1
Sun, X1
Oyamada, A1
Yamada, H1
Kira, J1
Yoshikai, Y1
Rapic, S1
Vangestel, C1
Verhaeghe, J1
Thomae, D1
Pauwels, P1
Van den Wyngaert, T1
Staelens, S1
Stroobants, S1
Chen, X1
Yang, Y1
Berger, I1
Khalid, U1
Patel, A2
Cai, J1
Farwell, MD1
Langer, C1
Aggarwal, C1
Albelda, SM1
Katz, SI1
Hegazy, AN1
Klein, C1
Melstrom, LG1
Bentrem, DJ1
Salabat, MR1
Kennedy, TJ1
Ding, XZ1
Strouch, M1
Rao, SM1
Witt, RC1
Ternent, CA1
Talamonti, MS1
Bell, RH1
Adrian, TA1
Frick, LR1
Rapanelli, M1
Bussmann, UA1
Klecha, AJ1
Arcos, ML1
Genaro, AM1
Cremaschi, GA1
Ragni, MV1
Wu, W1
Liang, X1
Hsieh, CC1
Cortese-Hassett, A1
Lu, L1
Gao, Z1
Liu, FJ1
Liu, L1
Zhou, TY1
Lei, J1
Xu, L1
Liu, C1
Dai, J1
Chen, EQ1
Tang, H1
Dahal, BK1
Kosanovic, D1
Pamarthi, PK1
Sydykov, A1
Lai, YJ1
Kast, R1
Schirok, H1
Stasch, JP1
Ghofrani, HA1
Weissmann, N1
Grimminger, F1
Seeger, W1
Schermuly, RT1
Lomoio, S1
Necchi, D1
Mares, V1
Scherini, E1
Ross, HH1
Rahman, M1
Levkoff, LH1
Millette, S1
Martin-Carreras, T1
Dunbar, EM1
Reynolds, BA1
Laywell, ED1
Bortolatto, CF1
Jesse, CR1
Wilhelm, EA1
Ribeiro, LR1
Rambo, LM1
Royes, LF1
Roman, SS1
Nogueira, CW1
Clark, JR1
Earwood, JD1
Glazer, R2
Quenelle, DC1
Collins, DJ1
Rice, TL1
Lafontant, PJ1
Burns, AR1
Grivas, JA1
Lesch, MA1
Lala, TD1
Reuter, SP1
Field, LJ1
Frounfelter, TD1
Zhang, CC1
Yan, Z1
Li, W1
Kuszpit, K1
Painter, CL1
Zhang, Q1
Lappin, PB1
Nichols, T1
Lira, ME1
Affolter, T1
Fahey, NR1
Cullinane, C1
Spilker, M1
Zasadny, K1
O'Brien, P1
Buckman, D1
Wong, A1
Christensen, JG1
Davtyan, H1
Ghochikyan, A1
Movsesyan, N1
Ellefsen, B1
Petrushina, I1
Cribbs, DH1
Hannaman, D1
Evans, CF1
Agadjanyan, MG1
Falluel-Morel, A1
Sokolowski, K1
McCandlish, E1
Buckley, B1
DiCicco-Bloom, E1
Baharav, E1
Bar, M1
Taler, M1
Gil-Ad, I1
Karp, L1
Weinberger, A1
Weizman, A1
Zeng, J1
Yi, B1
Wang, Z1
Ning, J1
Wang, X1
Lu, K1
Huizinga, R1
Kreft, KL1
Onderwater, S1
Boonstra, JG1
Brands, R1
Hintzen, RQ1
Laman, JD1
Potten, CS2
Booth, D1
Cragg, NJ1
Tudor, GL1
O'Shea, JA1
Booth, C1
Meineke, FA1
Barthel, D1
Loeffler, M1
Weinelt, S1
Peters, S1
Bauer, P1
Mix, E1
Haas, SJ1
Dittmann, A1
Petrov, S1
Wree, A1
Cattaneo, E1
Knoblich, R1
Strauss, U1
Rolfs, A1
Luyt, CE1
Meddahi-Pellé, A1
Ho-Tin-Noe, B1
Colliec-Jouault, S1
Guezennec, J1
Louedec, L1
Prats, H1
Jacob, MP1
Osborne-Pellegrin, M1
Letourneur, D1
Michel, JB1
Shao, H1
Sun, D1
Sun, SL1
Cruze, JM1
Bora, N1
Kaplan, HJ1
Kang, Y1
Hebron, H1
Ozbun, L1
Mariano, J1
Minoo, P1
Jakowlew, SB1
Van Valckenborgh, E1
Croucher, PI1
De Raeve, H1
Carron, C1
De Leenheer, E1
Blacher, S1
Devy, L1
Noël, A1
De Bruyne, E1
Asosingh, K1
Van Riet, I1
Van Camp, B1
Vanderkerken, K1
Roychowdhury, S1
Baiocchi, RA1
Vourganti, S1
Bhatt, D1
Blaser, BW1
Freud, AG1
Chou, J1
Chen, CS2
Xiao, JJ1
Parthun, M1
Chan, KK1
Eisenbeis, CF1
Ferketich, AK1
Grever, MR1
Caligiuri, MA1
Han, SH1
Lotinun, S1
Sibonga, JD1
Turner, RT1
Walters, DM1
Antao-Menezes, A1
Ingram, JL1
Rice, AB1
Nyska, A1
Tani, Y1
Kleeberger, SR1
Bonner, JC1
Bauer, S1
Patterson, PH1
Hansen, BS1
Hussain, RZ1
Lovett-Racke, AE1
Thomas, JA1
Racke, MK1
Irony-Tur-Sinai, M1
Grigoriadis, N1
Lourbopoulos, A1
Pinto-Maaravi, F1
Abramsky, O1
Brenner, T1
Suryani, S1
Sutton, I1
Quinones, MP1
Kalkonde, Y1
Estrada, CA1
Jimenez, F1
Ramirez, R1
Mahimainathan, L1
Mummidi, S1
Choudhury, GG1
Martinez, H1
Adams, L1
Mack, M1
Reddick, RL1
Maffi, S1
Haralambous, S1
Probert, L1
Ahuja, SK1
Ahuja, SS1
Mnjoyan, ZH1
Doan, D1
Brandon, JL1
Felix, K1
Sitter, CL1
Rege, AA1
Brock, TA1
Fujise, K1
Mangiarúa, E1
Basso, N1
Dubner, D1
Ruiz, P1
Taquini, AC1
Liu, FC1
Fengler, H1
Franz, R1
Schmiegelow, P1
Müller, W1
Lindner, J2
Heinz, G1
Maudgal, PC1
De Clercq, E1
Descamps, J1
Missotten, L1
Wijnhoven, J1
Nishimura, M1
Epstein, WL1
Fukuyama, K1
McKenna, B1
Weir, DG1
Scott, JM1
Kahn, D1
Stadler, J1
Terblanche, J1
van Hoorn-Hickman, R1
Sakanashi, Y1
Takeya, M1
Yoshimura, T1
Feng, L1
Morioka, T1
Takahashi, K2
Cote, PJ1
Gerin, JL1
Ridray, S1
Field, CJ1
Kira, Y1
Nakaoka, T1
Hashimoto, E1
Okabe, F1
Asano, S1
Sekine, I1
Bochaton-Piallat, ML1
Gabbiani, F1
Gabbiani, G1
Naito, M1
Umeda, S1
Shultz, LD1
Gruppuso, PA1
Boylan, JM1
Bienieki, TC1
Curran, TR1
Terubayashi, H1
Tsuji, T1
Okamoto, S1
Ikebe, H1
Akagi, Y1
Ferrer, I1
Alcántara, S1
Catalá, I1
Zújar, MJ1
Wu, CL1
Melton, DW1
Trahair, JF1
Wing, SJ1
Horn, JL1
Peten, EP1
Striker, LJ1
Fogo, A1
Ichikawa, I1
Striker, GE1
Hay, KA1
Gaydos, A1
Tenser, RB1
García Bolao, I1
Merino, J1
Gil, MJ1
Martínez, A1
Grau, A1
Alegría, E1
Martínez-Caro, D1
Frisbie, DD1
Nixon, AJ1
Lukács, L1
István, M1
Tóth, P1
Pakala, R1
Benedict, CR1
Roy, S1
Barke, RA1
Loh, HH1
Gentle, A1
McBrien, NA1
Boyan, BD1
Caplan, AI1
Heckman, JD1
Lennon, DP1
Ehler, W1
Schwartz, Z1
Cao, S1
McGuire, JJ1
Rustum, YM1
Thomson, PJ1
McGurk, M1
Walton, GM1
Appleton, DR1
Theodossiou, C1
Schwarzenberger, P1
Pourgholami, MH1
Woon, L1
Almajd, R1
Akhter, J1
Bowery, P1
Morris, DL1
Ye, YN1
Liu, ES1
Shin, VY1
Koo, MW1
Li, Y1
Wei, EQ1
Matsui, H1
Cho, CH1
Summers, BC1
Margolis, TP1
Leib, DA1
Islam-Ali, BS1
Tisdale, MJ1
Rao, PM1
Nagamine, Y1
Roomi, MW1
Rajalakshmi, S1
Sarma, DS1
Uchiyama, Y1
Tamaki, T1
Fukuda, H1
Moody, TW1
Leyton, J1
Chan, D1
Brenneman, DC1
Fridkin, M1
Gelber, E1
Levy, A1
Gozes, I1
Beeton, C1
Wulff, H1
Barbaria, J1
Clot-Faybesse, O1
Pennington, M1
Bernard, D1
Cahalan, MD1
Chandy, KG1
Béraud, E1
Wang, JY1
Zhang, QS1
Guo, JS1
Hu, MY1
Adachi, Y1
Matsubara, S1
Muramatsu, T1
Curiel, DT1
Reynolds, PN1
Sedmera, D1
Hu, N1
Weiss, KM1
Keller, BB1
Denslow, S1
Thompson, RP1
Griffin, M1
Smith, LL1
Wynne, J1
Looney, WB1
Mayo, AA1
Kovacs, CJ1
Hopkins, HA1
Simon, R1
Morris, HP1
Bradfield, JW2
Cattell, V2
Palmer, KC1
Snider, GL1
Hayes, JA1
Aso, K1
Rabinowitz, I1
Farber, EM1
Gentry, G1
McGowan, J1
Barnett, J1
Nevins, R1
Allen, G1
Smith, J1
Andre, F2
Andre, C2
Fournier, S1
McCullough, JL1
Schreiber, SH1
Ziboh, VA1
Machemer, R1
Laqua, H1
Hara, Y2
Tomizawa, S2
Albert, DM1
Lahav, M1
Bhatt, PN1
Reid, TW1
Ward, RE1
Cykiert, RC1
Lin, TS1
Ward, DC1
Prusoff, WH1
Arquilla, ER1
Weringer, EJ1
Nakajo, M1
Hard, GC1
Barker, M1
Hoshino, T1
Wheeler, KT1
Wilson, CB1
Bergsagel, DE1
Librach, SL1
Fishman, JA1
Ryan, GB1
Karnovsky, MJ1
Beighlie, DJ1
Teplitz, RL1
Middleton, PJ1
Petric, M1
Szymanski, MT1
Bevan, RD1
van Marthens, E1
Bevan, JA1
Jones, CL1
Buch, S1
Post, M1
McCulloch, L1
Liu, E1
Eddy, AA1
Ishiwata, K1
Takahashi, T1
Iwata, R1
Tomura, M1
Tada, M1
Itoh, J1
Kameyama, M1
Ido, T1
Koh, DR1
Fung-Leung, WP1
Ho, A1
Gray, D1
Acha-Orbea, H1
Mak, TW1
Kashani, SA2
Chang, TM2
Gobé, GC1
Axelsen, RA1
Fraginals, R1
Lepoittevin, JP1
Benezra, C1
Armstrong, R1
Friedrich, VL1
Holmes, KV1
Dubois-Dalcq, M1
Parekh, HK1
Chitnis, MP1
Matsushima, S1
Shichi, H1
Sweeney, JE1
Höhmann, CF1
Oster-Granite, ML1
Coyle, JT1
Cavagna, S1
Borman, LS1
Branda, RF1
Livne, E1
Weiss, A1
Silbermann, M1
Zucoloto, S1
Muccilo, G1
Wright, NA1
Alison, MR1
Ehrlich, MG1
Hawrylewicz, EJ1
Lelieveld, P1
Mulder, JH1
Nacey, JN1
Horsfall, DJ1
Delahunt, B1
Marshall, VR1
Malo, C1
Morin, CL1
Mitrovic, DR1
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Greenwood, BM1
Bradley-Moore, AM1
Bryceson, AD1
Palit, A1
Scheinberg, MA1
Cathcart, ES1
Wolf, RH1
Felsenfeld, O1
Brannon, RB1
Greer, WE1
Goffinet, DR1
Brown, JM1
Bagshaw, MA1
Kaplan, HS1
Paulini, K1
Körner, B1
Beneke, G2
Endres, R1
Rabes, H1
Hartenstein, R1
Scholze, P1
Narayan, O1
McFarland, HF1
Johnson, RT1
Leibowitz, HM1
Kupferman, A1
Mayor, MB1
Moskowitz, RW1
Gloor, BP1
Hughes, BF1
Gomolka, D1
Hawrylko, E1
Mackaness, GB2
Sugar, J1
Varnell, E1
Centifanto, Y1
Kaufman, HE1
Bottomley, JP1
Cooper, EH1
Maruyama, Y1
Lee, TC1
Sullivan, S1
Shapiro, WR2
Shin, KH1
Nakagawa, H1
Tsurufuji, S1
Lee, KT1
Nam, SC1
Florentin, RA1
Thomas, WA1
Gimbrone, MA1
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Kalina, RE1
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Lesch, R1
Oehlert, W1
Schreiber, G1
Jesdinsky, HJ1
Wüst, GP1
Waldeyer, M1
Bradley, WG1
Asbury, AK1
Warnatz, H1
Scheiffarth, F1
Kuntz, H1
Phillips, RS1
Wolstencroft, RA1
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Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Deoxythymidine and Deoxycytidine Treatment for Thymidine Kinase 2 (TK2) Deficiency[NCT03639701]Phase 1/Phase 223 participants (Actual)Interventional2017-05-16Active, not recruiting
Could Positon Emission Tomography With Radiolabelled 3'-Deoxy-3'-(18)F-Fluoro-L-Thymidine be a Theranostic Tool During Erlotinib Treatment in Non-small Cell Lung Cancer Patients ?[NCT02069418]Phase 280 participants (Anticipated)Interventional2014-02-28Active, not recruiting
A Study of 18F-FLT Positron Emission Tomography (PET)/Computed Tomography Imaging in Pediatrics With Myeloproliferative Neoplasms[NCT03121599]3 participants (Actual)Interventional2017-06-11Terminated (stopped due to Delayed study materials, poor recruitment)
A Study of 18F-FLT Positron Emission Tomography/Computed Tomography (PET/CT) Imaging in Cases of Prefibrotic/Early Primary Myelofibrosis (PMF) and Essential Thrombocythemia (ET)[NCT03116542]21 participants (Anticipated)Interventional2017-05-07Recruiting
Markers of T Cell Suppression: Antimalarial Treatment and Vaccine Responses in Healthy Malian Adults[NCT02544048]49 participants (Actual)Observational2015-09-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for thymidine and Disease Models, Animal

ArticleYear
Telbivudine: a new nucleoside analogue for the treatment of chronic hepatitis B.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:4

    Topics: Animals; Antiviral Agents; Disease Models, Animal; Hepatitis B, Chronic; Humans; Lamivudine; Nucleos

2005
Solid tumor models for the assessment of different treatment modalities: II: rapid, intermediate, and slow growing transplantable rat hepatomas.
    Life sciences, 1976, Feb-15, Volume: 18, Issue:4

    Topics: alpha-Fetoproteins; Animals; Carcinoma, Hepatocellular; Cell Division; Cyclic AMP; Cyclic GMP; Disea

1976
Fat-protein interaction, defined 2-generation studies.
    Progress in clinical and biological research, 1986, Volume: 222

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Cell Transformation, Neoplastic; Cocarcinoge

1986
Injury and repair of arterial tissue: histochemical alterations.
    Angiology, 1974, Volume: 25, Issue:10

    Topics: Animals; Arteries; Arteriosclerosis; Autoradiography; Collagen; Disease Models, Animal; DNA; Elastin

1974

Other Studies

176 other studies available for thymidine and Disease Models, Animal

ArticleYear
PD1 blockade alters cell-cycle distribution and affects 3'-deoxy-3'-[
    Annals of nuclear medicine, 2022, Volume: 36, Issue:11

    Topics: Animals; Cell Division; Cell Line, Tumor; Dideoxynucleosides; Disease Models, Animal; Fluorodeoxyglu

2022
Efficient base editing with high precision in rabbits using YFE-BE4max.
    Cell death & disease, 2020, 01-20, Volume: 11, Issue:1

    Topics: Albinism; Animals; Base Sequence; Cytidine Deaminase; Cytosine; Disease Models, Animal; Embryo, Mamm

2020
Disruption of hepatic one-carbon metabolism impairs mitochondrial function and enhances macrophage activity in methionine-choline-deficient mice.
    The Journal of nutritional biochemistry, 2020, Volume: 81

    Topics: Adenosine; Animals; Carbon; Choline; Choline Deficiency; Diet; Disease Models, Animal; Fatty Liver;

2020
Deoxycytidine and Deoxythymidine Treatment for Thymidine Kinase 2 Deficiency.
    Annals of neurology, 2017, Volume: 81, Issue:5

    Topics: Animals; Antimetabolites; Deoxycytidine Monophosphate; Disease Models, Animal; DNA, Mitochondrial; D

2017
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
    International immunopharmacology, 2018, Volume: 55

    Topics: Animals; Antiviral Agents; Disease Models, Animal; Fibrosis; Hepatitis B virus; Humans; Inflammation

2018
Metabolomic profiling of the effects of Curcumae rhizoma and Sparganii rhizome on stress-led blood stasis.
    Pakistan journal of pharmaceutical sciences, 2018, Volume: 31, Issue:1(Suppl.)

    Topics: Amino Acids; Animals; Blood; Blood Circulation; Blood Viscosity; Carbon; Curcuma; Disease Models, An

2018
Chromosome Transplantation: Correction of the Chronic Granulomatous Disease Defect in Mouse Induced Pluripotent Stem Cells.
    Stem cells (Dayton, Ohio), 2019, Volume: 37, Issue:7

    Topics: Aminopterin; Animals; Base Sequence; Cell Differentiation; Chromosomes, Mammalian; Clone Cells; CRIS

2019
Imaging mass spectrometry reveals heterogeneity of proliferation and metabolism in atherosclerosis.
    JCI insight, 2019, 06-06, Volume: 4, Issue:11

    Topics: Animals; Aorta; Atherosclerosis; Cell Proliferation; Disease Models, Animal; Foam Cells; Leukocytes;

2019
Limits of [18F]-FLT PET as a biomarker of proliferation in oncology.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Proliferation; Dideoxynucleosides; Disease Models, Anima

2013
A benzodiazepine impairs the neurogenic and behavioural effects of fluoxetine in a rodent model of chronic stress.
    Neuropharmacology, 2013, Volume: 72

    Topics: Animals; Antidepressive Agents; Benzodiazepines; Brain-Derived Neurotrophic Factor; Diazepam; Diseas

2013
Flaviviruses are sensitive to inhibition of thymidine synthesis pathways.
    Journal of virology, 2013, Volume: 87, Issue:17

    Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Dengue Virus; Disease Models, Animal; DN

2013
Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse.
    Brain : a journal of neurology, 2013, Volume: 136, Issue:Pt 9

    Topics: Animals; Body Patterning; Cell Proliferation; Disease Models, Animal; Embryo, Mammalian; Female; Fol

2013
Gene therapy using a liver-targeted AAV vector restores nucleoside and nucleotide homeostasis in a murine model of MNGIE.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2014, Volume: 22, Issue:5

    Topics: Animals; Dependovirus; Disease Models, Animal; DNA, Mitochondrial; Genetic Therapy; Genetic Vectors;

2014
Deoxynucleoside stress exacerbates the phenotype of a mouse model of mitochondrial neurogastrointestinal encephalopathy.
    Brain : a journal of neurology, 2014, Volume: 137, Issue:Pt 5

    Topics: Age Factors; Animals; Body Weight; Brain; Deoxyribonucleosides; Disease Models, Animal; Intestinal P

2014
A functional 12T-insertion polymorphism in the ATP1A1 promoter confers decreased susceptibility to hypertension in a male Sardinian population.
    PloS one, 2015, Volume: 10, Issue:1

    Topics: Adult; Aged; Animals; Disease Models, Animal; Essential Hypertension; Genetic Predisposition to Dise

2015
Maternal dietary uridine causes, and deoxyuridine prevents, neural tube closure defects in a mouse model of folate-responsive neural tube defects.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:4

    Topics: Animals; Deoxyuridine; Disease Models, Animal; Female; Folic Acid; Folic Acid Deficiency; Glycine Hy

2015
Anticancer activity of a thymidine quinoxaline conjugate is modulated by cytosolic thymidine pathways.
    BMC cancer, 2015, Mar-21, Volume: 15

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cytosol; Disease Models, Animal; Gene Expression;

2015
Efficacy of N-methanocarbathymidine against genital herpes simplex virus type 2 shedding and infection in guinea pigs.
    Antiviral chemistry & chemotherapy, 2015, Volume: 24, Issue:1

    Topics: Acute Disease; Animals; Antiviral Agents; Disease Models, Animal; Female; Guinea Pigs; Herpes Genita

2015
Thymidine-Dependent Staphylococcus aureus Small-Colony Variants Are Induced by Trimethoprim-Sulfamethoxazole (SXT) and Have Increased Fitness during SXT Challenge.
    Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Chronic Disease; Disease Models, Animal; Drug Re

2015
Requirement of CD30 expression on CD4 T cells in the pathogenesis of experimental autoimmune encephalomyelitis.
    Journal of neuroimmunology, 2016, Feb-15, Volume: 291

    Topics: Animals; CD4-Positive T-Lymphocytes; Cytokines; Disease Models, Animal; Dose-Response Relationship,

2016
Evaluation of [
    Molecular imaging and biology, 2017, Volume: 19, Issue:1

    Topics: Adenosine Triphosphate; Animals; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; Dideoxyn

2017
Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging.
    Oncotarget, 2017, Apr-11, Volume: 8, Issue:15

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, An

2017
Ex vivo priming of CD4 T cells converts immunological tolerance into effective antitumor immunity in a murine model of acute lymphoblastic leukemia.
    Leukemia, 2008, Volume: 22, Issue:11

    Topics: Animals; CD4-Positive T-Lymphocytes; Cell Proliferation; Dendritic Cells; Disease Models, Animal; Fe

2008
Overexpression of 5-lipoxygenase in colon polyps and cancer and the effect of 5-LOX inhibitors in vitro and in a murine model.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-15, Volume: 14, Issue:20

    Topics: Adenoma; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Cell Proliferation; Colonic Neoplasms; Col

2008
Involvement of thyroid hormones in the alterations of T-cell immunity and tumor progression induced by chronic stress.
    Biological psychiatry, 2009, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Cell Proliferation; Concanavalin A; Corticosterone; Disease Models, Animal; Disease Progres

2009
Factor VIII-pulsed dendritic cells reduce anti-factor VIII antibody formation in the hemophilia A mouse model.
    Experimental hematology, 2009, Volume: 37, Issue:6

    Topics: Animals; Antibodies; Antibody Formation; Cytokines; Dendritic Cells; Disease Models, Animal; Factor

2009
Application of hepatitis B virus replication mouse model.
    World journal of gastroenterology, 2010, Apr-28, Volume: 16, Issue:16

    Topics: Animals; Antiviral Agents; Disease Models, Animal; Drug Resistance, Viral; Enzyme-Linked Immunosorbe

2010
Therapeutic efficacy of azaindole-1 in experimental pulmonary hypertension.
    The European respiratory journal, 2010, Volume: 36, Issue:4

    Topics: Animals; Azabicyclo Compounds; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Hemody

2010
A single episode of neonatal seizures alters the cerebellum of immature rats.
    Epilepsy research, 2011, Volume: 93, Issue:1

    Topics: Animals; Animals, Newborn; Autoradiography; Calbindins; Cell Count; Cell Proliferation; Cerebellum;

2011
Ethynyldeoxyuridine (EdU) suppresses in vitro population expansion and in vivo tumor progression of human glioblastoma cells.
    Journal of neuro-oncology, 2011, Volume: 105, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Comet Assay;

2011
Protective effect of 2,2'-dithienyl diselenide on kainic acid-induced neurotoxicity in rat hippocampus.
    Neuroscience, 2011, Oct-13, Volume: 193

    Topics: Analysis of Variance; Animals; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship,

2011
N-Methanocarbathymidine is more effective than acyclovir for treating neonatal herpes simplex virus infection in guinea pigs.
    Antiviral research, 2011, Volume: 92, Issue:2

    Topics: Acyclovir; Animals; Animals, Newborn; Antiviral Agents; Disease Models, Animal; Guinea Pigs; Herpes

2011
Efficacy of orally administered low dose N-methanocarbathymidine against lethal herpes simplex virus type-2 infections of mice.
    Antiviral chemistry & chemotherapy, 2011, Nov-17, Volume: 22, Issue:3

    Topics: Administration, Oral; Animals; Antiviral Agents; Disease Models, Animal; Dose-Response Relationship,

2011
The giant danio (D. aequipinnatus) as a model of cardiac remodeling and regeneration.
    Anatomical record (Hoboken, N.J. : 2007), 2012, Volume: 295, Issue:2

    Topics: Animals; Cell Proliferation; Deoxyuridine; Disease Models, Animal; Granulation Tissue; Inflammation;

2012
[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Mar-01, Volume: 18, Issue:5

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle Checkpoints; Cell Proliferation; Cycli

2012
[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Mar-01, Volume: 18, Issue:5

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle Checkpoints; Cell Proliferation; Cycli

2012
[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Mar-01, Volume: 18, Issue:5

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle Checkpoints; Cell Proliferation; Cycli

2012
[(18)F]FLT-PET imaging does not always "light up" proliferating tumor cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Mar-01, Volume: 18, Issue:5

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Cell Cycle Checkpoints; Cell Proliferation; Cycli

2012
Delivery of a DNA vaccine for Alzheimer's disease by electroporation versus gene gun generates potent and similar immune responses.
    Neuro-degenerative diseases, 2012, Volume: 10, Issue:1-4

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antibodies; Biolistics; Disease Models, Animal; E

2012
N-acetyl cysteine treatment reduces mercury-induced neurotoxicity in the developing rat hippocampus.
    Journal of neuroscience research, 2012, Volume: 90, Issue:4

    Topics: Acetylcysteine; Analysis of Variance; Animals; Animals, Newborn; Cell Death; Cells, Cultured; Cerebr

2012
Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis.
    Neuroimmunomodulation, 2012, Volume: 19, Issue:5

    Topics: Analysis of Variance; Animals; Arthritis, Rheumatoid; Concanavalin A; Cyclooxygenase 2; Cytokines; C

2012
Effect of annexin A2 on hepatopulmonary syndrome rat serum-induced proliferation of pulmonary arterial smooth muscle cells.
    Respiratory physiology & neurobiology, 2013, Jan-15, Volume: 185, Issue:2

    Topics: Animals; Annexin A2; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Down-Regulation; H

2013
Endotoxin- and ATP-neutralizing activity of alkaline phosphatase as a strategy to limit neuroinflammation.
    Journal of neuroinflammation, 2012, Dec-11, Volume: 9

    Topics: Adenosine Triphosphate; Adult; Alkaline Phosphatase; Animals; Antigens, CD; Blood Vessels; Brain; Ce

2012
Cell kinetic studies in the murine ventral tongue epithelium: mucositis induced by radiation and its protection by pretreatment with keratinocyte growth factor (KGF).
    Cell proliferation, 2002, Volume: 35 Suppl 1

    Topics: Animals; Cell Division; Cell Movement; Disease Models, Animal; Epithelial Cells; Fibroblast Growth F

2002
Ciliary neurotrophic factor overexpression in neural progenitor cells (ST14A) increases proliferation, metabolic activity, and resistance to stress during differentiation.
    Journal of neuroscience research, 2003, Jan-15, Volume: 71, Issue:2

    Topics: Animals; Apomorphine; Apoptosis; Blotting, Western; Cell Differentiation; Cell Division; Cells, Cult

2003
Low-molecular-weight fucoidan promotes therapeutic revascularization in a rat model of critical hindlimb ischemia.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 305, Issue:1

    Topics: Animals; Anticoagulants; Capillaries; Cells, Cultured; Chemokine CXCL12; Chemokines, CXC; Disease Mo

2003
Expression of B7 molecules in the eye during experimental autoimmune anterior uveitis (EAAU).
    Current eye research, 2002, Volume: 25, Issue:5

    Topics: Animals; Antibodies; Antigens; Antigens, CD; Autoimmune Diseases; B7-1 Antigen; B7-2 Antigen; Cattle

2002
Nkx2.1 transcription factor in lung cells and a transforming growth factor-beta1 heterozygous mouse model of lung carcinogenesis.
    Molecular carcinogenesis, 2004, Volume: 40, Issue:4

    Topics: Animals; Blotting, Northern; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expressio

2004
Multifunctional role of matrix metalloproteinases in multiple myeloma: a study in the 5T2MM mouse model.
    The American journal of pathology, 2004, Volume: 165, Issue:3

    Topics: Animals; Annexin A5; Apoptosis; Bone Diseases; Cell Division; Diet; Disease Models, Animal; Enzyme I

2004
Selective efficacy of depsipeptide in a xenograft model of Epstein-Barr virus-positive lymphoproliferative disorder.
    Journal of the National Cancer Institute, 2004, Oct-06, Volume: 96, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Burkitt Lymphoma; Caspase Inhibitors; Cell Division; Cell

2004
Evidence that the cells responsible for marrow fibrosis in a rat model for hyperparathyroidism are preosteoblasts.
    Endocrinology, 2005, Volume: 146, Issue:9

    Topics: Animals; Body Weight; Core Binding Factors; Disease Models, Animal; Extracellular Matrix; Female; Hy

2005
Susceptibility of signal transducer and activator of transcription-1-deficient mice to pulmonary fibrogenesis.
    The American journal of pathology, 2005, Volume: 167, Issue:5

    Topics: Animals; Bleomycin; Blotting, Western; Cell Proliferation; Cells, Cultured; Collagen; Disease Models

2005
The cell cycle-apoptosis connection revisited in the adult brain.
    The Journal of cell biology, 2005, Nov-21, Volume: 171, Issue:4

    Topics: Animals; Apoptosis; Biotin; Brain; Bromodeoxyuridine; Cell Cycle; Disease Models, Animal; DNA; DNA R

2005
Multiple toll-like receptor agonists act as potent adjuvants in the induction of autoimmunity.
    Journal of neuroimmunology, 2006, Volume: 172, Issue:1-2

    Topics: Adaptor Proteins, Signal Transducing; Adjuvants, Pharmaceutic; Animals; Autoimmunity; Cell Prolifera

2006
Amelioration of autoimmune neuroinflammation by recombinant human alpha-fetoprotein.
    Experimental neurology, 2006, Volume: 198, Issue:1

    Topics: alpha-Fetoproteins; Analysis of Variance; Animals; Antibodies; Axons; CD11b Antigen; Cytokines; Dise

2006
An interferon-gamma-producing Th1 subset is the major source of IL-17 in experimental autoimmune encephalitis.
    Journal of neuroimmunology, 2007, Volume: 183, Issue:1-2

    Topics: Animals; Cell Proliferation; Central Nervous System; Cytokines; Disease Models, Animal; Encephalomye

2007
Role of astrocytes and chemokine systems in acute TNFalpha induced demyelinating syndrome: CCR2-dependent signals promote astrocyte activation and survival via NF-kappaB and Akt.
    Molecular and cellular neurosciences, 2008, Volume: 37, Issue:1

    Topics: Animals; Astrocytes; Cell Count; Chemokine CCL2; Chemokines; Demyelinating Diseases; Disease Models,

2008
The critical role of the intrinsic VSMC proliferation and death programs in injury-induced neointimal hyperplasia.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:5

    Topics: Animals; Apoptosis; Bromodeoxyuridine; Carotid Artery Injuries; Carotid Artery, Common; Catheterizat

2008
Evidence of early structural change in the artery wall of two-kidney one-clip Goldblatt hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:8

    Topics: Animals; Blood Pressure; Cardiomegaly; Collagen; Disease Models, Animal; DNA; Elastin; Hyperplasia;

1982
[Effects of Epimedium sagittatum and Cistanche deserticola on DNA synthesis in "Yang-insufficiency" animal model induced by hydroxyurea].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1984, Volume: 4, Issue:8

    Topics: Animals; China; Disease Models, Animal; DNA; Drug Combinations; Hydroxyurea; Male; Mice; Plant Extra

1984
[Chondrocyte proliferation in joint cartilages in beginning arthrosis--experimental studies].
    Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR, 1983, Volume: 16, Issue:4

    Topics: Animals; Autoradiography; Cartilage, Articular; Cell Division; Disease Models, Animal; Female; Joint

1983
[Experimental wound healing. New results on wound granulation tissue and epidermal reparation (3H-thymidine autoradiography)].
    Die Medizinische Welt, 1983, Dec-30, Volume: 34, Issue:51-52

    Topics: Animals; Autoradiography; Disease Models, Animal; Epidermal Cells; Granulation Tissue; Male; Rats; R

1983
Experimental stroma herpes simplex keratitis. Influence of treatment with topical bromovinyldeoxyuridine and trifluridine.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:4

    Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Corneal Diseases; Disease Models, Animal; Drug Adminis

1982
Autotransplantation of hepatic granulomas into the skin of mice with Schistosoma mansoni infection.
    The Journal of investigative dermatology, 1982, Volume: 79, Issue:3

    Topics: Animals; Autoradiography; Cytoplasm; Dermatologic Surgical Procedures; Disease Models, Animal; DNA;

1982
The induction of functional vitamin B-12 deficiency in rats by exposure to nitrous oxide.
    Biochimica et biophysica acta, 1980, Mar-20, Volume: 628, Issue:3

    Topics: Animals; Bone Marrow; Deoxyuridine; Disease Models, Animal; DNA; Female; Folic Acid; Formyltetrahydr

1980
Thymidine kinase: an inexpensive index of liver regeneration in a large animal model.
    Gastroenterology, 1980, Volume: 79, Issue:5 Pt 1

    Topics: Animals; Carbon Radioisotopes; Disease Models, Animal; DNA; Female; Hepatectomy; Liver Regeneration;

1980
Kinetics of macrophage subpopulations and expression of monocyte chemoattractant protein-1 (MCP-1) in bleomycin-induced lung injury of rats studied by a novel monoclonal antibody against rat MCP-1.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Base Sequence; Bleomycin; Blotting, Northern; Cell

1994
In vitro activation of woodchuck lymphocytes measured by radiopurine incorporation and interleukin-2 production: implications for modeling immunity and therapy in hepatitis B virus infection.
    Hepatology (Baltimore, Md.), 1995, Volume: 22, Issue:3

    Topics: Animals; Antigens, Viral; Cells, Cultured; Culture Media; Disease Models, Animal; Epitopes; Hepatiti

1995
Hyperinsulinemia and smooth muscle cell proliferation.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1995, Volume: 19 Suppl 1

    Topics: Acarbose; Animals; Arteriosclerosis; Blood Glucose; Cell Division; Disease Models, Animal; DNA; Fast

1995
A diet producing a low diabetes incidence modifies immune abnormalities in diabetes-prone BB rats.
    The Journal of nutrition, 1995, Volume: 125, Issue:10

    Topics: Animals; Autoimmune Diseases; Cells, Cultured; Diabetes Mellitus; Diet; Disease Models, Animal; Ener

1995
Effect of long-term cyclic mechanical load on protein synthesis and morphological changes in cultured myocardial cells from neonatal rat.
    Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:2

    Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Cardiomegaly; Cell Size; Cells, Cultured; Disease M

1994
Heterogeneity of rat aortic smooth muscle cell replication during development: correlation with replicative activity after experimental endothelial denudation in adults.
    Journal of submicroscopic cytology and pathology, 1994, Volume: 26, Issue:1

    Topics: Animals; Animals, Newborn; Aorta, Thoracic; Arteriosclerosis; Cell Division; Disease Models, Animal;

1994
The role of macrophage colony-stimulating factor in hepatic glucan-induced granuloma formation in the osteopetrosis mutant mouse defective in the production of macrophage colony-stimulating factor.
    The American journal of pathology, 1994, Volume: 144, Issue:6

    Topics: Animals; Autoradiography; Cell Division; Disease Models, Animal; DNA; Glucans; Granuloma; Immunohist

1994
Evidence for a direct hepatotrophic role for insulin in the fetal rat: implications for the impaired hepatic growth seen in fetal growth retardation.
    Endocrinology, 1994, Volume: 134, Issue:2

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Disease Model

1994
Proliferative changes of lens epithelial cells in rat and mouse galactose cataracts--examination using whole-mount preparations.
    Japanese journal of ophthalmology, 1993, Volume: 37, Issue:1

    Topics: Animals; Autoradiography; Cataract; Cell Division; Dietary Carbohydrates; Disease Models, Animal; Ep

1993
Experimentally induced laminar necrosis, status verrucosus, focal cortical dysplasia reminiscent of microgyria, and porencephaly in the rat.
    Experimental brain research, 1993, Volume: 94, Issue:2

    Topics: Animals; Animals, Newborn; Autoradiography; Biomarkers; Brain; Cerebral Cortex; Disease Models, Anim

1993
Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice.
    Nature genetics, 1993, Volume: 3, Issue:3

    Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Brain; Caffeine; Cell Division; Cells, Cultured

1993
Failure of short-term luminal IGF-I to protect against atrophy in a model of fetal esophageal atresia.
    Journal of pediatric surgery, 1995, Volume: 30, Issue:11

    Topics: Animals; Atrophy; Biological Transport; Cell Division; Deglutition; Disease Models, Animal; Embryoni

1995
The molecular basis of increased glomerulosclerosis after blockade of the renin angiotensin system in growth hormone transgenic mice.
    Molecular medicine (Cambridge, Mass.), 1994, Volume: 1, Issue:1

    Topics: Actins; Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ani

1994
Inhibition of herpes simplex virus reactivation by dipyridamole in a mouse model.
    Journal of medical virology, 1996, Volume: 50, Issue:2

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Dipyridamole; Disease Models, Animal; Ganglia, Spin

1996
[Growth factors and mitogenic activity in experimental hypercholesterolemia].
    Revista espanola de cardiologia, 1996, Volume: 49, Issue:12

    Topics: 3T3 Cells; Animals; Blood Platelets; Cells, Cultured; Cholesterol, Dietary; Disease Models, Animal;

1996
Insulin-like growth factor 1 and corticosteroid modulation of chondrocyte metabolic and mitogenic activities in interleukin 1-conditioned equine cartilage.
    American journal of veterinary research, 1997, Volume: 58, Issue:5

    Topics: Adrenal Cortex Hormones; Analysis of Variance; Animals; Anti-Inflammatory Agents; Cartilage; Cell Di

1997
Lymphonodal response to sensitization with 2,4-dinitrochlorobenzene (DNCB) in laboratory rats.
    Acta chirurgica Hungarica, 1997, Volume: 36, Issue:1-4

    Topics: Animals; Antigens; Autoradiography; Dinitrochlorobenzene; Disease Models, Animal; DNA; Female; Injec

1997
Effect of serotonin and thromboxane A2 on endothelial cell proliferation: effect of specific receptor antagonists.
    The Journal of laboratory and clinical medicine, 1998, Volume: 131, Issue:6

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cell Division; Cells, C

1998
MU-opioid receptor-knockout mice: role of mu-opioid receptor in morphine mediated immune functions.
    Brain research. Molecular brain research, 1998, Oct-30, Volume: 61, Issue:1-2

    Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Animals; B

1998
Modulation of scleral DNA synthesis in development of and recovery from induced axial myopia in the tree shrew.
    Experimental eye research, 1999, Volume: 68, Issue:2

    Topics: Animals; Cell Division; Disease Models, Animal; DNA; Female; Male; Myopia; Refraction, Ocular; Scler

1999
Osteochondral progenitor cells in acute and chronic canine nonunions.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1999, Volume: 17, Issue:2

    Topics: Alkaline Phosphatase; Animals; Bone Development; Bony Callus; Cartilage; Cell Division; Cells, Cultu

1999
Antitumor activity of ZD1694 (tomudex) against human head and neck cancer in nude mouse models: role of dosing schedule and plasma thymidine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1999, Volume: 5, Issue:7

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Administration Schedule; Female; Floxur

1999
Tritiated thymidine and bromodeoxyuridine double-labelling studies on growth factors and oral epithelial proliferation in the mouse.
    Archives of oral biology, 1999, Volume: 44, Issue:9

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Animals; Antimetabolites; Bromodeoxyuridine; Ca

1999
Propylthiouracil reduces xenograft tumor growth in an athymic nude mouse prostate cancer model.
    The American journal of the medical sciences, 2000, Volume: 319, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Contrast Media; Disease Models, Animal; Humans; Hypothyroi

2000
In vitro and in vivo suppression of growth of hepatocellular carcinoma cells by albendazole.
    Cancer letters, 2001, Apr-10, Volume: 165, Issue:1

    Topics: Albendazole; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Count; Cell Cycle; Cell

2001
A mechanistic study of proliferation induced by Angelica sinensis in a normal gastric epithelial cell line.
    Biochemical pharmacology, 2001, Jun-01, Volume: 61, Issue:11

    Topics: Angelica sinensis; Animals; Apiaceae; Cell Division; Cells, Cultured; Disease Models, Animal; DNA; D

2001
Herpes simplex virus type 1 corneal infection results in periocular disease by zosteriform spread.
    Journal of virology, 2001, Volume: 75, Issue:11

    Topics: Adolescent; Animals; beta-Galactosidase; Chlorocebus aethiops; Corneal Diseases; Dermatitis, Periora

2001
Effect of a tumour-produced lipid-mobilizing factor on protein synthesis and degradation.
    British journal of cancer, 2001, Jun-15, Volume: 84, Issue:12

    Topics: Animals; Blotting, Western; Cachexia; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Disease Mode

2001
Orotic acid, a new promoter for experimental liver carcinogenesis.
    Toxicologic pathology, 1984, Volume: 12, Issue:2

    Topics: 1,2-Dimethylhydrazine; Animals; Arginine; Carcinogens; Diet; Disease Models, Animal; DNA; gamma-Glut

1984
Relationship between functional deficit and severity of experimental fast-strain injury of rat skeletal muscle.
    European journal of applied physiology, 2001, Volume: 85, Issue:1-2

    Topics: Animals; Disease Models, Animal; Male; Mitosis; Muscle Contraction; Muscle, Skeletal; Organ Size; Ra

2001
VIP receptor antagonists and chemotherapeutic drugs inhibit the growth of breast cancer cells.
    Breast cancer research and treatment, 2001, Volume: 68, Issue:1

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclic AMP; Di

2001
Selective blockade of T lymphocyte K(+) channels ameliorates experimental autoimmune encephalomyelitis, a model for multiple sclerosis.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Nov-20, Volume: 98, Issue:24

    Topics: Animals; Calcium Channel Blockers; CD4-Positive T-Lymphocytes; Cells, Cultured; Cnidarian Venoms; Di

2001
Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats.
    World journal of gastroenterology, 2001, Volume: 7, Issue:1

    Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Carbon Tetrachloride; Cell Division; Col

2001
Midkine promoter-based adenoviral suicide gene therapy to midkine-positive pediatric tumor.
    Journal of pediatric surgery, 2002, Volume: 37, Issue:4

    Topics: Adenoviridae; Animals; Carrier Proteins; Chemical and Drug Induced Liver Injury; Cytokines; Disease

2002
Cellular changes in experimental left heart hypoplasia.
    The Anatomical record, 2002, Jun-01, Volume: 267, Issue:2

    Topics: Animals; Apoptosis; Autoradiography; Cell Division; Chick Embryo; Disease Models, Animal; Fluorescen

2002
Changes in transglutaminase activity in an experimental model of pulmonary fibrosis induced by paraquat.
    British journal of experimental pathology, 1979, Volume: 60, Issue:6

    Topics: Animals; Collagen; Disease Models, Animal; DNA; Female; gamma-Glutamyltransferase; Hydroxyproline; L

1979
The mesangial cell in glomerulonephritis. I. Mechanisms of hypercellularity in experimental immune complex glomerulonephritis.
    Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 36, Issue:5

    Topics: Animals; Disease Models, Animal; Glomerulonephritis; Immune Complex Diseases; Injections, Intravenou

1977
Cellular proliferation induced in the lung by cadmium aerosol.
    The American review of respiratory disease, 1975, Volume: 112, Issue:2

    Topics: Aerosols; Animals; Autoradiography; Cadmium Poisoning; Chlorides; Disease Models, Animal; DNA; Lung;

1975
The role of prostaglandin E, cyclic AMP, and cyclic GMP in the proliferation of guinea-pig ear skin stimulated by topical application of vitamin A acid.
    The Journal of investigative dermatology, 1976, Volume: 67, Issue:2

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Administration, Topical; Animals; Cell Division; Cyclic AMP; Cy

1976
Arabinosylthymine, a selective inhibitor of herpesvirus replication: current status of in vivo studies.
    Advances in ophthalmology = Fortschritte der Augenheilkunde = Progres en ophtalmologie, 1979, Volume: 38

    Topics: Animals; Arabinonucleosides; Cricetinae; Deoxyribonucleosides; Disease Models, Animal; Drug Evaluati

1979
The mesangial cell in glomerulonephritis. II. Mesangial proliferation caused by Habu snake venom in the rat.
    Laboratory investigation; a journal of technical methods and pathology, 1977, Volume: 36, Issue:5

    Topics: Animals; Cell Division; Cell Movement; Disease Models, Animal; Glomerulonephritis; Injections, Intra

1977
Measurement of glycoprotein content and cell kinetics in preulcerous gastric mucosa.
    Digestive diseases and sciences, 1979, Volume: 24, Issue:9

    Topics: Anaphylaxis; Animals; Disease Models, Animal; Female; Gastric Mucosa; Glycoproteins; Kinetics; Male;

1979
Cell proliferation kinetics of epidermis in the essential fatty acid deficient rat.
    The Journal of investigative dermatology, 1978, Volume: 70, Issue:6

    Topics: Animals; Autoradiography; Cell Count; Cell Cycle; Disease Models, Animal; Fatty Acids, Essential; Hy

1978
Pigment epithelium proliferation in retinal detachment (massive periretinal proliferation).
    American journal of ophthalmology, 1975, Volume: 80, Issue:1

    Topics: Animals; Autoradiography; Cell Division; Disease Models, Animal; DNA; Epithelial Cells; Epithelium;

1975
[Paper disk granuloma method for experimental granuloma in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:5

    Topics: Absorption; Age Factors; Animals; Anti-Inflammatory Agents; Disease Models, Animal; DNA; Drug Evalua

1977
[The antigranuloma effect of fluocinolone acetonide by paper disk granuloma in rats (author's transl)].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1977, Volume: 73, Issue:5

    Topics: Adrenalectomy; Animals; Disease Models, Animal; DNA; Female; Fluocinolone Acetonide; Granuloma; In V

1977
Successful therapy of herpes hominis keratitis in rabbits by 5-iodo-5'-amino-2'5'-dideoxyuridine (AIU): a novel analog of thymidine.
    Investigative ophthalmology, 1976, Volume: 15, Issue:6

    Topics: Administration, Topical; Animals; Deoxyuridine; Disease Models, Animal; Drug Administration Schedule

1976
Wound healing: a model for the study of diabetic angiopathy.
    Diabetes, 1976, Volume: 25, Issue:2 SUPPL

    Topics: Animals; Capillaries; Collagen; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Disease Mode

1976
Thymus-dependent lymphocyte function in dimethylnitrosamine-induced renal carcinogenesis is not depressed.
    Oncology, 1975, Volume: 31, Issue:3-4

    Topics: Animals; Carcinogens; Dimethylnitrosamine; Disease Models, Animal; Female; Immunity, Cellular; Kidne

1975
Chemotherapeutic implications of early tumor cell growth in an animal brain-tumor model.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:4

    Topics: Animals; Brain Neoplasms; Cell Division; Disease Models, Animal; DNA, Neoplasm; Male; Neoplasms, Exp

1975
Mouse myeloma. A model for studies of cell kinetics.
    Archives of internal medicine, 1975, Volume: 135, Issue:1

    Topics: Alkylating Agents; Animals; Bone Marrow; Bone Marrow Cells; Bone Neoplasms; Cell Division; Cells, Cu

1975
Endothelial regeneration in the rat carotid artery and the significance of endothelial denudation in the pathogenesis of myointimal thickening.
    Laboratory investigation; a journal of technical methods and pathology, 1975, Volume: 32, Issue:3

    Topics: Animals; Arteriosclerosis; Autoradiography; Carotid Artery Diseases; Disease Models, Animal; Endothe

1975
Repair of UV damaged DNA in systemic lupus erythematosus.
    The Journal of rheumatology, 1975, Volume: 2, Issue:2

    Topics: Adult; Animals; Autoradiography; Breeding; Bromodeoxyuridine; Disease Models, Animal; DNA; Fibroblas

1975
Propagation of infantile gastroenteritis virus (orbi-group) in conventional and germfree piglets.
    Infection and immunity, 1975, Volume: 12, Issue:6

    Topics: Animals; Animals, Newborn; Antibody Formation; Antigens, Viral; Cross Infection; Disease Models, Ani

1975
Hyperplasia of vascular smooth muscle in experimental hypertension in the rabbit.
    Circulation research, 1976, Volume: 38, Issue:6 Suppl 2

    Topics: Animals; Arteries; Autoradiography; Disease Models, Animal; DNA; Extracellular Space; Hyperplasia; H

1976
Renal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in rats.
    The American journal of pathology, 1992, Volume: 141, Issue:6

    Topics: Animals; Basement Membrane; Blotting, Northern; Cell Division; Collagen; Disease Models, Animal; DNA

1992
Tumor diagnosis by PET: potential of seven tracers examined in five experimental tumors including an artificial metastasis model.
    International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology, 1992, Volume: 19, Issue:6

    Topics: Animals; Carbon Radioisotopes; Deoxyglucose; Diagnosis, Differential; Disease Models, Animal; Floxur

1992
Less mortality but more relapses in experimental allergic encephalomyelitis in CD8-/- mice.
    Science (New York, N.Y.), 1992, May-22, Volume: 256, Issue:5060

    Topics: Animals; CD8 Antigens; Crosses, Genetic; Death; Disease Models, Animal; DNA Replication; Encephalomy

1992
Effects of hepatic stimulatory factor released from free or microencapsulated hepatocytes on galactosamine induced fulminant hepatic failure animal model.
    Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 1991, Volume: 19, Issue:3

    Topics: Animals; Cell-Free System; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Models,

1991
Physicochemical characteristics of hepatic stimulatory factor prepared from cell free supernatant of hepatocyte cultures.
    Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology, 1991, Volume: 19, Issue:3

    Topics: Acrylic Resins; Autoradiography; Calibration; Cell-Free System; Cells, Cultured; Chemical and Drug I

1991
The role of apoptosis in the development of renal cortical tubular atrophy associated with healed experimental renal papillary necrosis.
    Pathology, 1991, Volume: 23, Issue:3

    Topics: Animals; Atrophy; Autoradiography; Body Weight; Cell Count; Cell Death; Disease Models, Animal; Kidn

1991
Sensitizing capacity of three methyl alkanesulphonates: a murine in vivo and in vitro model of allergic contact dermatitis.
    Archives of dermatological research, 1990, Volume: 282, Issue:7

    Topics: Alkanesulfonates; Animals; Dermatitis, Contact; Disease Models, Animal; Drug Hypersensitivity; Epide

1990
In vitro analysis of the oligodendrocyte lineage in mice during demyelination and remyelination.
    The Journal of cell biology, 1990, Volume: 111, Issue:3

    Topics: Animals; Autoradiography; Cell Differentiation; Cell Division; Coronaviridae Infections; Demyelinati

1990
Effect of alterations in permeability by nonionic surfactants on adriamycin cytotoxicity in murine tumor models in vitro.
    Oncology, 1990, Volume: 47, Issue:6

    Topics: Animals; Cell Membrane Permeability; Disease Models, Animal; DNA Replication; Doxorubicin; Drug Inte

1990
Possible mechanism of immunosuppression by gramicidin S of S antigen-induced experimental autoimmune uveoretinitis.
    Journal of ocular pharmacology, 1989,Fall, Volume: 5, Issue:3

    Topics: Animals; Antigens; Arrestin; Autoimmune Diseases; Biological Transport; Cells, Cultured; Disease Mod

1989
Neurogenesis of the basal forebrain in euploid and trisomy 16 mice: an animal model for developmental disorders in Down syndrome.
    Neuroscience, 1989, Volume: 31, Issue:2

    Topics: Acetylcholinesterase; Animals; Cell Differentiation; Cholinergic Fibers; Disease Models, Animal; Dow

1989
Role of histamine in the cell turnover changes associated with experimental gastric ulceration in the mastomys.
    Gastroenterology, 1985, Volume: 88, Issue:2

    Topics: Animals; Cell Division; Cimetidine; Clemastine; Disease Models, Animal; Female; Histamine H1 Antagon

1985
Nutritional folate deficiency in Chinese hamster ovary cells. I. Characterization of the pleiotropic response and its modulation by nucleic acid precursors.
    Journal of cellular physiology, 1989, Volume: 140, Issue:2

    Topics: Animals; Cell Adhesion; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cricetinae; Disease Mod

1989
Articular chondrocytes lose their proliferative activity with aging yet can be restimulated by PTH-(1-84), PGE1, and dexamethasone.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:4

    Topics: Aging; Alprostadil; Animals; Cartilage, Articular; Cell Division; Cells, Cultured; Dexamethasone; Di

1989
Chronic effects of alcohol on the epithelium of the small intestine using two experimental models.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1985, Volume: 49, Issue:4

    Topics: Alcoholism; Animals; Body Weight; Cell Division; Diet; Disease Models, Animal; Energy Intake; Epithe

1985
Degradative enzyme systems in osteoarthritic cartilage.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1985, Volume: 3, Issue:2

    Topics: Acid Phosphatase; Animals; Cartilage, Articular; Cytidine; Disease Models, Animal; Edetic Acid; Egta

1985
Three tumor sensitivity tests evaluated with mouse tumors.
    International journal of cell cloning, 1987, Volume: 5, Issue:4

    Topics: Animals; Antineoplastic Agents; Colony-Forming Units Assay; Disease Models, Animal; Lung Neoplasms;

1987
The assessment of urinary catheter toxicity using cell cultures: validation by comparison with an animal model.
    The Journal of urology, 1986, Volume: 136, Issue:3

    Topics: Animals; Cells, Cultured; Disease Models, Animal; Dogs; Epithelium; Fibroblasts; Humans; Latex; Male

1986
Establishment of an animal model of ovalbumin sensitised mouse to study protein induced enteropathy.
    Gut, 1986, Volume: 27, Issue:11

    Topics: Animals; Disease Models, Animal; DNA; Dose-Response Relationship, Immunologic; Immunization; Intesti

1986
Histochemical and cellular changes induced in the rabbit knee joint by an intraarticular implantation of a sheet of polyethylene.
    Laboratory investigation; a journal of technical methods and pathology, 1985, Volume: 53, Issue:2

    Topics: Animals; Bone and Bones; Cartilage, Articular; Cell Survival; Disease Models, Animal; Foreign-Body R

1985
Immunosuppression in children with malaria.
    Lancet (London, England), 1972, Jan-22, Volume: 1, Issue:7743

    Topics: Acute Disease; Animals; Antibody Formation; Antigens; Burkitt Lymphoma; Candida; Child; Disease Mode

1972
Casein-induced experimental amyloidosis. III. Response to mitogens, allogeneic cells, and graft-versus-host reactions in the murine model.
    Immunology, 1974, Volume: 27, Issue:5

    Topics: Amyloidosis; Animals; Antibody Formation; B-Lymphocytes; Caseins; Concanavalin A; Disease Models, An

1974
Low protein intake and response to Escherichia coli 055 infection in patas monkeys.
    The American journal of digestive diseases, 1970, Volume: 15, Issue:9

    Topics: Animals; Antibody Formation; Antibody-Producing Cells; Carbon Isotopes; Disease Models, Animal; DNA;

1970
Prolonged carotid arterial radiosensitizer infusion and radiation therapy of mouse gliomas.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1972, Volume: 114, Issue:1

    Topics: Animals; Brain Neoplasms; Bromine; Carotid Arteries; Catheterization; Craniotomy; Cytidine; Deoxyrib

1972
A quantitative study of the growth of connective tissue: investigations on implanted polyester-polyurethane sponges.
    Connective tissue research, 1974, Volume: 2, Issue:4

    Topics: Animals; Autoradiography; Body Weight; Cell Count; Collagen; Connective Tissue; Disease Models, Anim

1974
Specific stages of cellular response to homeostatic control during diethylnitrosamine-induced liver carcinogenesis.
    Experientia, 1970, Dec-15, Volume: 26, Issue:12

    Topics: Adenosine Triphosphatases; Animals; Autoradiography; Carcinogens; Carcinoma, Hepatocellular; Cell Tr

1970
Effects of viral infection on nervous system development. II. Attempts to modify bluetongue-virus-induced malformations with cyclophosphamide and antithymocyte serum.
    The American journal of pathology, 1972, Volume: 68, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Autoradiography; Bluetongue; Brain; Brain Diseases; Cyclopho

1972
Anti-inflammatory effectiveness in the cornea of topically administered prednisolone.
    Investigative ophthalmology, 1974, Volume: 13, Issue:10

    Topics: Acetates; Administration, Topical; Animals; Autoradiography; Condiments; Cornea; Disease Models, Ani

1974
Metabolic studies in experimentally-induced degenerative joint disease in the rabbit.
    The Journal of rheumatology, 1974, Volume: 1, Issue:1

    Topics: Animals; Autoradiography; Cartilage, Articular; Cell Division; Disease Models, Animal; Femur; Glycin

1974
On the question of the origin of macrophages in the retina and the vitreous following photocoagulation (autoradiographic investigations by means of 3H-thymidine).
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1974, May-17, Volume: 190, Issue:3

    Topics: Animals; Autoradiography; Cell Movement; Ciliary Body; Disease Models, Animal; Eye Diseases; Hematop

1974
Autoradiography of cell wall-deficient variants of Proteus mirabilis in a rat kidney model.
    Investigative urology, 1974, Volume: 11, Issue:5

    Topics: Animals; Autoradiography; Cell Wall; Disease Models, Animal; Female; Kidney Medulla; Proteus Infecti

1974
The kinetics of lymphoid cell proliferation in the tuberculous mouse spleen.
    Cellular immunology, 1972, Volume: 5, Issue:1

    Topics: Animals; Antigens, Bacterial; Autoradiography; Bone Marrow Cells; Bone Marrow Transplantation; Cell

1972
Trifluorothymidine treatment of herpetic iritis in rabbits and ocular penetration.
    Investigative ophthalmology, 1973, Volume: 12, Issue:7

    Topics: Adenine; Animals; Antiviral Agents; Aqueous Humor; Arabinose; Disease Models, Animal; Fluorine; Hypo

1973
Cell proliferation in colonic mucosa and carcinoma of the colon.
    Proceedings of the Royal Society of Medicine, 1973, Volume: 66, Issue:12

    Topics: Animals; Colon; Colonic Neoplasms; Disease Models, Animal; DNA; Humans; Intestinal Mucosa; Intestina

1973
Age cohort variation of tumor cells.
    Radiology, 1973, Volume: 109, Issue:1

    Topics: Animals; Cell Division; Disease Models, Animal; DNA, Neoplasm; Fluorouracil; Hydroxyurea; Lymphoma;

1973
The chemotherapy of intracerebral vs subcutaneous murine gliomas. A comparative study of the effect of VM 26.
    Archives of neurology, 1974, Volume: 30, Issue:3

    Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Disease Models, Animal; DNA, Neoplasm; Ependymoma;

1974
Rebound of rat carrageenin granuloma following cessation of anti-inflammatory steroid therapy.
    Biochemical pharmacology, 1974, Jan-15, Volume: 23, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Collagen; Disease Models, Animal; DNA; Granuloma; Hy

1974
Genesis of atherosclerosis in swine fed high fat-cholesterol diets.
    The Medical clinics of North America, 1974, Volume: 58, Issue:2

    Topics: Animals; Aorta, Abdominal; Arteriosclerosis; Autoradiography; Cell Division; Cholesterol, Dietary; D

1974
Tumor growth and neovascularization: an experimental model using the rabbit cornea.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:2

    Topics: Acrylamides; Animals; Autoradiography; Carbon; Cell-Free System; Cornea; Disease Models, Animal; Eye

1974
Thymidine kinase activity and incorporation of thymidine into DNA in zinc-deficient tissue.
    The Journal of laboratory and clinical medicine, 1974, Volume: 83, Issue:4

    Topics: Animals; Body Weight; Carbon Radioisotopes; Connective Tissue; Deficiency Diseases; Disease Models,

1974
Induction of endothelial cell proliferation in rat retinal venules by chemical and indirect physical trauma.
    Investigative ophthalmology, 1974, Volume: 13, Issue:8

    Topics: Animals; Autoradiography; Cell Division; Disease Models, Animal; Endothelium; Eye Injuries; Inflamma

1974
Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets.
    Diabetologia, 1970, Volume: 6, Issue:3

    Topics: Age Factors; Animals; Autoradiography; Blood Glucose; Cell Count; Cytoplasmic Granules; Diabetes Mel

1970
Studies in the diabetic mutant mouse. II. Electron microscopy of pancreatic islets.
    Diabetologia, 1970, Volume: 6, Issue:3

    Topics: Animals; Autoradiography; Cytoplasmic Granules; Diabetes Mellitus; Disease Models, Animal; Endoplasm

1970
[Investigations on cell proliferation in white adipose tissue of albino mice obesified by administration of aurothioglucose].
    Pathologia et microbiologia, 1971, Volume: 37, Issue:4

    Topics: Adipose Tissue; Animals; Autoradiography; Blood Vessels; Body Weight; Cell Count; Cell Division; Con

1971
Cell-mediated resistance to aerogenic infection of the lung.
    The American review of respiratory disease, 1971, Volume: 104, Issue:6

    Topics: Aerosols; Animals; Autoradiography; Disease Models, Animal; Female; Germ-Free Life; Immunity, Cellul

1971
Use of cell separation at 1 g for cytokinetic studies in spontaneous AKR leukemia.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:3

    Topics: Animals; Autoradiography; Cell Fractionation; Centrifugation, Density Gradient; Disease Models, Anim

1972
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
    Cancer research, 1972, Volume: 32, Issue:10

    Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Iso

1972
Degenerative changes of neurocytes in the light of autoradiographic investigations.
    Pathologia Europaea, 1971, Volume: 6, Issue:2

    Topics: Adenine; Amino Acids; Animals; Autoradiography; Brain; Carbon Isotopes; Cerebral Cortex; Disease Mod

1971
[Changes in the gastric mucosa in experimental uremia. Behavior of the parietal cells in the gastric mucosa of uremic mice. An autoradiographic study].
    Zeitschrift fur Gastroenterologie, 1971, Volume: 9, Issue:9

    Topics: Animals; Autoradiography; Cell Division; Disease Models, Animal; Gastric Mucosa; Injections, Intrape

1971
Repair of the post-extraction alveolus in the Wistar rat. A histologic and autoradiographic study.
    Acta odontologica Scandinavica, 1970, Volume: 28, Issue:4

    Topics: Alveolar Process; Animals; Autoradiography; Bone Regeneration; Disease Models, Animal; Fibroblasts;

1970
[Influence of 5-ethyl-2'-deoxyuridine (EDU) on the regeneration of experimentally damaged cornea].
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1970, Volume: 179, Issue:4

    Topics: Animals; Cautery; Cell Migration Inhibition; Cornea; Corneal Injuries; Deoxyuridine; Disease Models,

1970
[Autoradiographic and biochemical investigations of the rat liver in the acute stage of aminonucleoside nephrosis].
    Beitrage zur pathologischen Anatomie und zur allgemeinen Pathologie, 1969, Volume: 139, Issue:3

    Topics: Analysis of Variance; Animals; Autoradiography; Carbon Isotopes; Disease Models, Animal; DNA; Epithe

1969
[In vitro effect of various cytostatics on the H3-thymidine incorporation in the explantates of heterotransplanted human tumor (GW-39)].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1969, Volume: 75

    Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Humans; Neoplasm Transplantation; Neoplasms,

1969
Studies in the diabetic mutant mouse. 3. Physiological factors associated with alterations in beta cell proliferation.
    Diabetologia, 1970, Volume: 6, Issue:3

    Topics: Age Factors; Animal Nutritional Physiological Phenomena; Animals; Autoradiography; Blood Glucose; Ce

1970
Radioautographic studies of Schwann cell behavior. I. Acrylamide neuropathy in the mouse.
    Journal of neuropathology and experimental neurology, 1970, Volume: 29, Issue:3

    Topics: Acrylic Resins; Animals; Autoradiography; Brain; Cell Count; Disease Models, Animal; Female; Mice; M

1970
Studies on lymphocyte transformation in experimental allergic encephalomyelitis.
    Journal of neuropathology and experimental neurology, 1970, Volume: 29, Issue:4

    Topics: Animals; Autoradiography; Brain; Culture Techniques; Disease Models, Animal; Encephalomyelitis, Auto

1970
Immunity to malaria. 3. Possible occurrence of a cell-mediated immunity to Plasmodium knowlesi in chronically infected and Freund's complete adjuvant-sensitized monkeys.
    Experimental parasitology, 1970, Volume: 28, Issue:2

    Topics: Animals; Antibody Formation; Chromium; Chromium Isotopes; Culture Media; Disease Models, Animal; DNA

1970
[Origin and development of inflammatory cells in granulation tissue. Autoradiographic studies with 3 H-thymidine on a cotton pellet granuloma of the rat].
    Klinische Wochenschrift, 1970, Jul-15, Volume: 48, Issue:14

    Topics: Animals; Autoradiography; Blood Cells; Disease Models, Animal; Fibroblasts; Gossypium; Granulation T

1970