Page last updated: 2024-11-06

thymidine and Disease Exacerbation

thymidine has been researched along with Disease Exacerbation in 21 studies

Research Excerpts

ExcerptRelevanceReference
"There is limited data on the efficacy and outcome of telbivudine (LdT) therapy in patients with chronic hepatitis B and compensated cirrhosis."9.19Comparing the efficacy and clinical outcome of telbivudine and entecavir naïve patients with hepatitis B virus-related compensated cirrhosis. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lin, MT; Tsai, MC; Tseng, PL; Yen, YH; Yu, HC, 2014)
"The aims of this study were to evaluate the possibility of using (11)C-methionine ((11)C-MET) and (11)C-4'-thiothymidine ((11)C-4DST) whole-body PET/CT for the imaging of amino acid metabolism and DNA synthesis, respectively, when searching for bone marrow involvement in patients with multiple myeloma (MM) and to compare these findings with those for (18)F-FDG PET/CT and aspiration cytology."7.81Comparison of (11)C-4'-thiothymidine, (11)C-methionine, and (18)F-FDG PET/CT for the detection of active lesions of multiple myeloma. ( Hagiwara, S; Hirai, R; Inoue, T; Ishiwata, K; Ito, K; Kubota, K; Minamimoto, R; Miwa, A; Miyata, Y; Morooka, M; Okasaki, M; Toyohara, J, 2015)
"There is limited data on the efficacy and outcome of telbivudine (LdT) therapy in patients with chronic hepatitis B and compensated cirrhosis."5.19Comparing the efficacy and clinical outcome of telbivudine and entecavir naïve patients with hepatitis B virus-related compensated cirrhosis. ( Chang, KC; Chen, CH; Chiu, KW; Hu, TH; Hung, CH; Lee, CM; Lin, MT; Tsai, MC; Tseng, PL; Yen, YH; Yu, HC, 2014)
"Serum IL-21 levels were measured by enzyme immunoassay in 75 HBeAg-positive chronic hepatitis B (CHB) patients undergoing telbivudine treatment."5.16High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B. ( Abbott, WG; Dong, YH; Hou, JL; Huang, X; Jiang, XT; Li, YY; Liu, ZH; Ma, SW; Naoumov, NV; Sun, J; Sun, XF; Tang, LB; Zhang, YX, 2012)
"The aims of this study were to evaluate the possibility of using (11)C-methionine ((11)C-MET) and (11)C-4'-thiothymidine ((11)C-4DST) whole-body PET/CT for the imaging of amino acid metabolism and DNA synthesis, respectively, when searching for bone marrow involvement in patients with multiple myeloma (MM) and to compare these findings with those for (18)F-FDG PET/CT and aspiration cytology."3.81Comparison of (11)C-4'-thiothymidine, (11)C-methionine, and (18)F-FDG PET/CT for the detection of active lesions of multiple myeloma. ( Hagiwara, S; Hirai, R; Inoue, T; Ishiwata, K; Ito, K; Kubota, K; Minamimoto, R; Miwa, A; Miyata, Y; Morooka, M; Okasaki, M; Toyohara, J, 2015)
" To examine changes in phosphorylated Smad3 signalling before and after anti-HBV therapies, we chose 27 patients with chronic hepatitis B who underwent baseline and follow-up biopsies at 52 weeks from the start of nucleoside analogue treatments (Lamivudine 100 mg daily or Telbivudine 600 mg daily)."3.80Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection. ( Deng, YR; Jin, QL; Lian, ZX; Matsuzaki, K; Moritoki, Y; Murata, M; Niu, JQ; Tsuneyama, K; Yamaguchi, T; Yoshida, K, 2014)
"Twenty-one consecutive chronic hepatitis B patients experiencing severe acute exacerbation were treated with either telbivudine or entecavir."3.79On-treatment mortality predictors in chronic hepatitis B patients experiencing severe acute exacerbation: a prospective observational study. ( Chang, MY; Chen, YC; Hsu, CW; Yeh, CT, 2013)
"Pravastatin was active only in medium with lipoprotein-deficient serum."2.68Simvastatin impairs mitogen-induced proliferation of malignant B-lymphocytes from humans--in vitro and in vivo studies. ( Angelin, B; Juliusson, G; Vitols, S, 1997)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (23.81)18.2507
2000's8 (38.10)29.6817
2010's8 (38.10)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, YC1
Hsu, CW1
Chang, MY1
Yeh, CT1
Park, YH1
Kim, BK1
Kim, JK1
Kim, HC1
Kim, DY1
Park, JY1
Han, KH1
Kim, SU1
Shin, SH1
Hahn, KY1
Ahn, SH1
Deng, YR1
Yoshida, K2
Jin, QL1
Murata, M2
Yamaguchi, T1
Tsuneyama, K1
Moritoki, Y1
Niu, JQ1
Matsuzaki, K2
Lian, ZX1
Tsai, MC1
Yu, HC1
Hung, CH1
Lee, CM1
Chiu, KW1
Lin, MT1
Tseng, PL1
Chang, KC1
Yen, YH1
Chen, CH1
Hu, TH1
Okasaki, M1
Kubota, K1
Minamimoto, R1
Miyata, Y1
Morooka, M1
Ito, K1
Ishiwata, K1
Toyohara, J1
Inoue, T1
Hirai, R1
Hagiwara, S1
Miwa, A1
Frick, LR1
Rapanelli, M1
Bussmann, UA1
Klecha, AJ1
Arcos, ML1
Genaro, AM1
Cremaschi, GA1
Mallet, V1
Vallet-Pichard, A1
Pol, S1
Mileshkin, L1
Hicks, RJ1
Hughes, BG1
Mitchell, PL1
Charu, V1
Gitlitz, BJ1
Macfarlane, D1
Solomon, B1
Amler, LC1
Yu, W1
Pirzkall, A1
Fine, BM1
Ma, SW1
Huang, X1
Li, YY1
Tang, LB1
Sun, XF1
Jiang, XT1
Zhang, YX1
Sun, J1
Liu, ZH1
Abbott, WG1
Dong, YH1
Naoumov, NV1
Hou, JL1
Awazu, M1
Omori, S1
Ishikura, K1
Hida, M1
Fujita, H1
Shao, H1
Sun, D1
Sun, SL1
Cruze, JM1
Bora, N1
Kaplan, HJ1
Terada, Y1
Kobayashi, T1
Kuwana, H1
Tanaka, H1
Inoshita, S1
Kuwahara, M1
Sasaki, S1
Fiszman, G1
Cattaneo, V1
de la Torre, E1
Español, A1
Colombo, L1
Sacerdote de Lustig, E1
Sales, ME1
Sekimoto, G1
Uemura, Y1
Sakaida, N1
Kaibori, M1
Kamiyama, Y1
Nishizawa, M1
Fujisawa, J1
Okazaki, K1
Seki, T1
Makita, S1
Nakamura, M1
Yoshida, H1
Hiramori, K1
Vitols, S1
Angelin, B1
Juliusson, G1
Alessandri, G1
Cornaglia-Ferraris, P1
Gullino, PM1
Amadori, D1
Silvestrini, R1
Hu, X1
Guo, Z1
Tianyun, P1
Pontén, F1
Wilander, E1
Andersson, S1
Pontén, J1
Matthews, E1
Yang, T1
Janulis, L1
Goodwin, S1
Kundu, SD1
Karpus, WJ1
Lee, C1
Koschmieder, S1
Hofmann, WK1
Kunert, J1
Wagner, S1
Ballas, K1
Seipelt, G1
Hoelzer, D1
Ottmann, OG1
Kalina, U1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Could Positon Emission Tomography With Radiolabelled 3'-Deoxy-3'-(18)F-Fluoro-L-Thymidine be a Theranostic Tool During Erlotinib Treatment in Non-small Cell Lung Cancer Patients ?[NCT02069418]Phase 280 participants (Anticipated)Interventional2014-02-28Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for thymidine and Disease Exacerbation

ArticleYear
The impact of human immunodeficiency virus on viral hepatitis.
    Liver international : official journal of the International Association for the Study of the Liver, 2011, Volume: 31 Suppl 1

    Topics: Adenine; Antiviral Agents; Deoxycytidine; Disease Progression; Drug Therapy, Combination; Emtricitab

2011
Prognostic and predictive value of thymidine labelling index in breast cancer.
    Breast cancer research and treatment, 1998, Volume: 51, Issue:3

    Topics: Breast Neoplasms; Disease Progression; Female; Humans; Predictive Value of Tests; Prognosis; Prospec

1998

Trials

4 trials available for thymidine and Disease Exacerbation

ArticleYear
Comparing the efficacy and clinical outcome of telbivudine and entecavir naïve patients with hepatitis B virus-related compensated cirrhosis.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:3

    Topics: Adult; Aged; Alanine Transaminase; Antiviral Agents; Disease Progression; DNA, Viral; Female; Guanin

2014
Changes in 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine positron emission tomography imaging in patients with non-small cell lung cancer treated with erlotinib.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, May-15, Volume: 17, Issue:10

    Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease Progression; Erlotinib Hydrochl

2011
High serum IL-21 levels after 12 weeks of antiviral therapy predict HBeAg seroconversion in chronic hepatitis B.
    Journal of hepatology, 2012, Volume: 56, Issue:4

    Topics: Adult; Alanine Transaminase; Antiviral Agents; Biomarkers; Disease Progression; DNA, Viral; Female;

2012
Simvastatin impairs mitogen-induced proliferation of malignant B-lymphocytes from humans--in vitro and in vivo studies.
    Lipids, 1997, Volume: 32, Issue:3

    Topics: Adult; Aged; B-Lymphocytes; Cell Division; Cholesterol; Chronic Disease; Disease Progression; Dose-R

1997

Other Studies

15 other studies available for thymidine and Disease Exacerbation

ArticleYear
On-treatment mortality predictors in chronic hepatitis B patients experiencing severe acute exacerbation: a prospective observational study.
    BMC research notes, 2013, Sep-02, Volume: 6

    Topics: Adult; Aged; alpha-Fetoproteins; Antiviral Agents; Bilirubin; Biomarkers; Disease Progression; Femal

2013
Long-term outcomes of chronic hepatitis B virus infection in the era of antiviral therapy in Korea.
    Journal of gastroenterology and hepatology, 2014, Volume: 29, Issue:5

    Topics: Adult; Age Factors; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; Female; Follow

2014
Reversible phospho-Smad3 signalling between tumour suppression and fibrocarcinogenesis in chronic hepatitis B infection.
    Clinical and experimental immunology, 2014, Volume: 176, Issue:1

    Topics: Adult; Antiviral Agents; Carcinoma, Hepatocellular; Disease Progression; DNA, Viral; Female; Hepatit

2014
Comparison of (11)C-4'-thiothymidine, (11)C-methionine, and (18)F-FDG PET/CT for the detection of active lesions of multiple myeloma.
    Annals of nuclear medicine, 2015, Volume: 29, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Bone Marrow; Carbon Radioisotopes; Disease Progression; Female; Fluo

2015
Involvement of thyroid hormones in the alterations of T-cell immunity and tumor progression induced by chronic stress.
    Biological psychiatry, 2009, Jun-01, Volume: 65, Issue:11

    Topics: Animals; Cell Proliferation; Concanavalin A; Corticosterone; Disease Models, Animal; Disease Progres

2009
The lack of cyclin kinase inhibitor p27(Kip1) ameliorates progression of diabetic nephropathy.
    Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:3

    Topics: Adaptor Proteins, Signal Transducing; Albuminuria; Animals; Blood Group Antigens; Carrier Proteins;

2003
Expression of B7 molecules in the eye during experimental autoimmune anterior uveitis (EAAU).
    Current eye research, 2002, Volume: 25, Issue:5

    Topics: Animals; Antibodies; Antigens; Antigens, CD; Autoimmune Diseases; B7-1 Antigen; B7-2 Antigen; Cattle

2002
Aldosterone stimulates proliferation of mesangial cells by activating mitogen-activated protein kinase 1/2, cyclin D1, and cyclin A.
    Journal of the American Society of Nephrology : JASN, 2005, Volume: 16, Issue:8

    Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Aldosterone; Animals; Blotting, Western; Cell Cycle; Ce

2005
Muscarinic receptors autoantibodies purified from mammary adenocarcinoma-bearing mice sera stimulate tumor progression.
    International immunopharmacology, 2006, Volume: 6, Issue:8

    Topics: Adenocarcinoma; Animals; Atropine; Autoantibodies; Blotting, Western; Carbachol; Cell Line, Tumor; C

2006
Chronic inflammation associated with hepatitis C virus infection perturbs hepatic transforming growth factor beta signaling, promoting cirrhosis and hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:1

    Topics: alpha-Fetoproteins; Biopsy; Carcinoma, Hepatocellular; Disease Progression; DNA Replication; Hepatit

2007
Effect of angiotensin II receptor blocker on angiotensin II stimulated DNA synthesis of cultured human aortic smooth muscle cells.
    Life sciences, 1995, Volume: 56, Issue:20

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Aorta; Arteriosclerosis; Biphenyl Compounds; Cell

1995
Angiogenic and angiostatic microenvironment in tumors--role of gangliosides.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:4

    Topics: Angiogenesis Inducing Agents; Cell Adhesion; Cell Division; Cell Membrane; Collagen; Culture Media;

1997
HPV typing and HPV16 E6-sequence variations in synchronous lesions of cervical squamous-cell carcinoma from Swedish patients.
    International journal of cancer, 1999, Sep-24, Volume: 83, Issue:1

    Topics: Adult; Carcinoma, Squamous Cell; Disease Progression; DNA-Binding Proteins; Female; Guanine; Humans;

1999
Down-regulation of TGF-beta1 production restores immunogenicity in prostate cancer cells.
    British journal of cancer, 2000, Volume: 83, Issue:4

    Topics: Animals; Cell Division; Cloning, Molecular; Disease Progression; DNA, Complementary; Down-Regulation

2000
TGF beta-induced SMAD2 phosphorylation predicts inhibition of thymidine incorporation in CD34+ cells from healthy donors, but not from patients with AML after MDS.
    Leukemia, 2001, Volume: 15, Issue:6

    Topics: Acute Disease; Adult; Antigens, CD34; Cell Division; Disease Progression; DNA Replication; DNA-Bindi

2001