thymidine has been researched along with Di Guglielmo Disease in 51 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In megakaryocyte-like human erythroleukemia (HEL) cells, ERK2 was found to be predominantly expressed and strongly activated by prostaglandin (PG) E(2), thrombin, and epinephrine." | 1.31 | Extracellular signal-regulated kinases and g protein-coupled receptors in megakaryocytic human erythroleukemia cells: selective activation, differential regulation, and dissociation from mitogenesis. ( Brass, LF; Shen, HW; Sung, KC; Wu, H; Wu, TF, 2002) |
| "Mouse erythroleukemia (Mel) cells are particularly sensitive to mutagenic agents between 18 and 24 h from the start of induction (Foresti, M." | 1.30 | Two periods of sensitivity to mutagens in induced Mel cells with different outcomes. ( Foresti, M; Geraci, G; Mele, F; Paoletti, I, 1997) |
| "[3H]thymidine incorporation was reduced in cells treated with this thioallyl compound, and analysis of high-molecular-weight DNA showed fragmentation compatible with apoptosis." | 1.30 | S-allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines. ( Anagnostou, A; Hooker, JL; Li, W; Sigounas, G; Steiner, M, 1997) |
| "5-Fluorouracil (5-FU) is a chemotherapeutic agent known to retard embryonic growth and induce cleft palate and limb deformities." | 1.30 | Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells. ( Elstein, KH; Kavlock, RJ; Lau, C; Mole, ML; Rogers, JM; Setzer, RW; Zucker, RM, 1997) |
| "Gossypol treatments inhibited cell multiplication at 10 and 20 micrograms/ml concentrations and this inhibitory effect increased with elevated dosage and prolonged treatment." | 1.28 | Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells. ( Baker, MA; Daehler, CC; Daly, EP; Kleemeyer, KM; Majumdar, SK, 1991) |
| "We isolated from the Rauscher erythroleukemia cell line (Red 5), a subclone (Red 5-1." | 1.28 | Erythropoietin binding and induced differentiation of Rauscher erythroleukemia cell line red 5-1.5. ( Barker, ME; Selleck, SE; Weiss, TL; Wintroub, BU, 1989) |
| "Thymidine incorporation was inhibited by the photodynamic effect depending on porphyrin concentration." | 1.28 | Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins. ( Ehrenberg, B; Faraggi, A; Malik, Z, 1989) |
| "K562 is an established human erythroleukemia cell line, inducible for hemoglobin synthesis by a variety of compounds including n-butyrate." | 1.27 | K562 human erythroleukemia cell variants resistant to growth inhibition by butyrate have deficient histone acetylation. ( Farley, BA; Kosciolek, B; La Bella, S; Ohlsson-Wilhelm, BM; Rowley, PT, 1984) |
| "and thymidine treatments may be due to thymidine-induced nucleotide pool imbalance with consequent inaccuracies in DNA repair." | 1.27 | Synergism between U.V. and thymidine treatments in the induction of cytogenetic damage in wild-type Friend erythroleukaemia cells. ( McKelvey, VJ; McKenna, PG, 1988) |
| "Fagaronine (Fine) is a novel antileukemic drug extracted from Fagara xanthoxyloides Lam." | 1.27 | Effect of fagaronine on cell cycle progression of human erythroleukemia K562 cells. ( Carpentier, Y; Comoë, L; Desoize, B; Jardillier, JC, 1988) |
| "After culture with 3H-thymidine murine erythroleukemia cells with more sites of DNA attached to the nuclear matrix have more labeled thymidine in their matrix-bound DNA than in their total DNA than do cells with fewer attachment sites." | 1.27 | Localization of AT-rich sequences at the nuclear matrix. ( Flickinger, RA, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (64.71) | 18.7374 |
| 1990's | 15 (29.41) | 18.2507 |
| 2000's | 3 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schuster, C | 1 |
| Fernbach, N | 1 |
| Rix, U | 1 |
| Superti-Furga, G | 1 |
| Holy, M | 1 |
| Freissmuth, M | 1 |
| Sitte, HH | 1 |
| Sexl, V | 1 |
| Bin, X | 1 |
| DiLiberto, M | 1 |
| Rifkind, RA | 2 |
| Marks, PA | 2 |
| Levenson, R | 1 |
| Kernen, J | 1 |
| Mitrani, A | 1 |
| Housman, D | 1 |
| Keller, P | 1 |
| Zownir, O | 1 |
| Morrow, J | 1 |
| Chang, CS | 1 |
| Sassa, S | 1 |
| Ohlsson-Wilhelm, BM | 3 |
| Farley, BA | 2 |
| Kosciolek, B | 1 |
| La Bella, S | 1 |
| Rowley, PT | 4 |
| Das, KC | 1 |
| Garewal, G | 1 |
| Mohanty, D | 1 |
| Foresti, M | 2 |
| Gaudio, L | 1 |
| Paoletti, I | 2 |
| Geraci, G | 2 |
| Jones, EW | 1 |
| Manning, R | 1 |
| Grant, S | 1 |
| Turner, A | 1 |
| Nelms, P | 1 |
| Yanovich, S | 1 |
| Yen, JJ | 1 |
| Hsieh, YC | 1 |
| Yen, CL | 1 |
| Chang, CC | 1 |
| Lin, S | 1 |
| Yang-Yen, HF | 1 |
| Hercus, TR | 1 |
| Bagley, CJ | 1 |
| Cambareri, B | 1 |
| Dottore, M | 1 |
| Woodcock, JM | 1 |
| Vadas, MA | 1 |
| Shannon, MF | 1 |
| Lopez, AF | 1 |
| Wen, D | 1 |
| Boissel, JP | 1 |
| Showers, M | 1 |
| Ruch, BC | 1 |
| Bunn, HF | 1 |
| Sola, JE | 1 |
| Colombani, PM | 1 |
| Mele, F | 1 |
| Sigounas, G | 1 |
| Hooker, JL | 1 |
| Li, W | 1 |
| Anagnostou, A | 1 |
| Steiner, M | 1 |
| Elstein, KH | 2 |
| Mole, ML | 1 |
| Setzer, RW | 1 |
| Zucker, RM | 2 |
| Kavlock, RJ | 1 |
| Rogers, JM | 1 |
| Lau, C | 1 |
| Boleti, H | 1 |
| Coe, IR | 1 |
| Baldwin, SA | 1 |
| Young, JD | 1 |
| Cass, CE | 1 |
| Anisimov, AG | 1 |
| Chekmasova, AA | 1 |
| Volkova, TO | 1 |
| Nemova, NN | 1 |
| Wu, H | 1 |
| Shen, HW | 1 |
| Wu, TF | 1 |
| Brass, LF | 1 |
| Sung, KC | 1 |
| Gambari, R | 1 |
| Terada, M | 1 |
| Bank, A | 1 |
| Lourenço, G | 1 |
| Embury, S | 1 |
| Schrier, SL | 1 |
| Kedes, LH | 1 |
| Preisler, HD | 1 |
| Lutton, JD | 1 |
| Giladi, M | 1 |
| Goldstein, K | 1 |
| Zanjani, ED | 1 |
| Sato, T | 1 |
| de Harven, E | 1 |
| Friend, C | 1 |
| Beckman, BS | 2 |
| Adams, DJ | 1 |
| Bair, KW | 1 |
| Green, AR | 1 |
| DeLuca, E | 1 |
| Begley, CG | 1 |
| Majumdar, SK | 1 |
| Daly, EP | 1 |
| Kleemeyer, KM | 1 |
| Daehler, CC | 1 |
| Baker, MA | 1 |
| Weiss, TL | 1 |
| Barker, ME | 1 |
| Selleck, SE | 1 |
| Wintroub, BU | 1 |
| Malik, Z | 1 |
| Ehrenberg, B | 1 |
| Faraggi, A | 1 |
| Liotti, FS | 1 |
| Menghini, AR | 1 |
| Guerrieri, P | 1 |
| Bianchi, R | 1 |
| Wilkinson, YA | 1 |
| McKenna, PG | 2 |
| Lewis, JP | 1 |
| McKie, VC | 1 |
| Faguet, GB | 1 |
| Felice, AE | 1 |
| Blanchard, MM | 1 |
| Barenton, B | 1 |
| Sullivan, A | 1 |
| Foster, B | 1 |
| Guyda, HJ | 1 |
| Posner, BI | 1 |
| Kopfler, W | 1 |
| Koury, P | 1 |
| Jeter, JR | 1 |
| Trakshel, GM | 1 |
| Maines, MD | 1 |
| McKelvey, VJ | 1 |
| Comoë, L | 1 |
| Carpentier, Y | 1 |
| Desoize, B | 1 |
| Jardillier, JC | 1 |
| Ruscetti, SK | 1 |
| Wickramasinghe, SN | 1 |
| Flickinger, RA | 1 |
| London, L | 1 |
| Perussia, B | 1 |
| Trinchieri, G | 1 |
| Paul, J | 1 |
| Hickey, I | 1 |
| Fredrickson, TN | 1 |
| Schultz, EF | 1 |
| LoBue, J | 1 |
| Alexander, P | 1 |
| Rubin, AD | 1 |
| Gordon, AS | 1 |
| Schmidt, M | 1 |
| Ostertag, W | 1 |
| Roesler, G | 1 |
| Krieg, CJ | 1 |
| Kind, J | 1 |
| Cole, T | 1 |
| Crozier, T | 1 |
| Gaedicke, G | 1 |
| Steinheider, G | 1 |
| Kluge, N | 1 |
| Dube, S | 1 |
| Huber, C | 2 |
| Huber, H | 2 |
| Schmalzl, F | 2 |
| Braunsteiner, H | 2 |
| Lederer, B | 1 |
| Bütterich, D | 1 |
| Crossen, PE | 1 |
| Fitzgerald, PH | 1 |
| Menzies, RC | 1 |
| Brehaut, LA | 1 |
| Todo, A | 1 |
51 other studies available for thymidine and Di Guglielmo Disease
| Article | Year |
|---|---|
Selective serotonin reuptake inhibitors--a new modality for the treatment of lymphoma/leukaemia?
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Transformation, Neoplastic; Fibrob | 2007 |
Releasing effect of thymidine on G1 phase arrest of erythroleukemia cells caused by FUDR and HMBA.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Clone Cells; Dact | 1984 |
DNA synthesis is not required for the commitment of murine erythroleukemia cells.
Topics: Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA; DNA Replication; Floxuridine; Kin | 1980 |
Bromodeoxyuridine resistance: thymidine transport and phosphorylation in Friend leukemia cells.
Topics: Animals; Biological Transport; Bromodeoxyuridine; Drug Resistance; Leukemia, Erythroblastic, Acute; | 1984 |
Induction of delta-aminolevulinic acid dehydratase in mouse Friend virus-transformed erythroleukemia cells during erythroid differentiation.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cross Reactions; Dimethyl Sulfoxide; Drug Antagoni | 1984 |
K562 human erythroleukemia cell variants resistant to growth inhibition by butyrate have deficient histone acetylation.
Topics: Acetylation; Benzidines; Butyrates; Butyric Acid; Cell Division; Electrophoresis, Polyacrylamide Gel | 1984 |
Derangement of DNA synthesis in erythroleukaemia. Normal deoxyuridine suppression and impaired thymidine incorporation in bone marrow culture.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Female; F | 1980 |
Inhibition of erythroid differentiation in MEL cells by UV irradiation. Cell cycle and DNA repair activity.
Topics: Animals; Cell Cycle; DNA; DNA Damage; DNA Repair; Erythroid Precursor Cells; Hydroxyurea; Leukemia, | 1993 |
Cytotoxic effects of membrane-active agents in human leukaemia cell lines.
Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Culture Media, Serum-Free; Dibucaine | 1995 |
Characterization of a multidrug resistant human erythroleukemia cell line (K562) exhibiting spontaneous resistance to 1-beta-D-arabinofuranosylcytosine.
Topics: Arabinofuranosylcytosine Triphosphate; Cytarabine; Deoxycytidine Kinase; DNA, Neoplasm; Drug Resista | 1995 |
Restoring the apoptosis suppression response to IL-5 confers on erythroleukemic cells a phenotype of IL-5-dependent growth.
Topics: Apoptosis; Base Sequence; Cell Division; DNA Primers; DNA, Neoplasm; Gene Expression; Humans; Interl | 1995 |
Specific human granulocyte-macrophage colony-stimulating factor antagonists.
Topics: Amino Acid Sequence; Animals; Cell Division; CHO Cells; Cloning, Molecular; Cricetinae; Granulocyte- | 1994 |
Erythropoietin structure-function relationships. Identification of functionally important domains.
Topics: Amino Acid Sequence; Animals; Biological Assay; Cell Division; Cell Line; Chlorocebus aethiops; Eryt | 1994 |
Modulation of multidrug resistance with antisense oligodeoxynucleotide to mdr1 mRNA.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Codon; Daunorubicin; Drug Resistance, Multi | 1996 |
Two periods of sensitivity to mutagens in induced Mel cells with different outcomes.
Topics: Animals; Cell Differentiation; Cell Division; Dimethyl Sulfoxide; DNA; Electrophoresis, Polyacrylami | 1997 |
S-allylmercaptocysteine, a stable thioallyl compound, induces apoptosis in erythroleukemia cell lines.
Topics: Apoptosis; Cell Cycle; Cell Division; Cysteine; DNA; DNA Fragmentation; Dose-Response Relationship, | 1997 |
Nucleoside-mediated mitigation of 5-fluorouracil-induced toxicity in synchronized murine erythroleukemic cells.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Cycle; Deoxycytidine; Deoxyguanine Nucleotides; Embry | 1997 |
Molecular identification of the equilibrative NBMPR-sensitive (es) nucleoside transporter and demonstration of an equilibrative NBMPR-insensitive (ei) transport activity in human erythroleukemia (K562) cells.
Topics: Adenosine; Affinity Labels; Binding Sites; Blotting, Northern; Carrier Proteins; Cell Division; Cell | 1997 |
[Combination of thymidine and dexamethasone increases the K562 tumor cells sensitivity to human leukocytes cytotoxicity].
Topics: Antineoplastic Agents, Hormonal; Cell Differentiation; Cytotoxicity, Immunologic; Dexamethasone; Dru | 2001 |
Extracellular signal-regulated kinases and g protein-coupled receptors in megakaryocytic human erythroleukemia cells: selective activation, differential regulation, and dissociation from mitogenesis.
Topics: Calcium; Cell Division; Cell Line; Enzyme Activation; Enzyme Activators; Gene Expression Regulation, | 2002 |
Synthesis of globin mRNA in relation to the cell cycle during induced murine erythroleukemia differentiation.
Topics: Acetamides; Animals; Cell Cycle; Cell Differentiation; Cells, Cultured; Diamines; Dimethyl Sulfoxide | 1978 |
Decreased ribosomal RNA content and in vitro RNA synthesis in purified bone marrow erythroblasts of patients with idiopathic ineffective erythropoiesis and DiGuglielmo disease.
Topics: Bone Marrow Cells; Erythroblasts; Erythrocytes; Erythropoiesis; Humans; Leukemia, Erythroblastic, Ac | 1978 |
Loss of clonogenicity in agar by differentiating erythroleukemic cells.
Topics: Agar; Animals; Autoradiography; Cattle; Cell Differentiation; Cell Division; Clone Cells; Culture Me | 1975 |
Increased virus budding from Friend erythroleukemic cells treated with dimethyl sulfoxide, dimethyl formamide, and/or bromodeoxyuridine in vitro.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Dimethyl Sulfoxide; Formamides; Friend murine leukemia | 1975 |
Nuclear protein kinase C activity is decreased in Friend erythroleukemia cells induced to differentiate.
Topics: Acetamides; Alkaloids; Cell Division; Cell Nucleus; Cell Transformation, Viral; Dimethyl Sulfoxide; | 1992 |
Polyploidy induction as a consequence of topoisomerase inhibition. A flow cytometric assessment.
Topics: Amsacrine; Animals; Camptothecin; Doxorubicin; Flow Cytometry; Friend murine leukemia virus; G2 Phas | 1991 |
Antisense SCL suppresses self-renewal and enhances spontaneous erythroid differentiation of the human leukaemic cell line K562.
Topics: Antisense Elements (Genetics); Basic Helix-Loop-Helix Transcription Factors; Blotting, Northern; Cel | 1991 |
Genotoxic effects of gossypol acetic acid on cultured murine erythroleukemia cells.
Topics: Animals; Cell Division; Cell Membrane; Chromosome Aberrations; DNA Damage; DNA Replication; Gossypol | 1991 |
Erythropoietin binding and induced differentiation of Rauscher erythroleukemia cell line red 5-1.5.
Topics: Animals; Cell Differentiation; Cell Line; DNA; Erythropoietin; Leukemia, Erythroblastic, Acute; Micr | 1989 |
Inactivation of erythrocytic, lymphocytic and myelocytic leukemic cells by photoexcitation of endogenous porphyrins.
Topics: Aminolevulinic Acid; Animals; Cell Survival; Humans; Leukemia; Leukemia, Erythroblastic, Acute; Leuk | 1989 |
Effects of dimethylsulfoxide on Friend erythroleukemic cell proliferation and on the activity of enzymes involved in this process.
Topics: Adenylyl Cyclases; Animals; Catalase; Cell Count; Cell Division; Cell Line; Dimethyl Sulfoxide; Frie | 1989 |
The effects of thymidine on deoxyribonucleotide pool levels, cytotoxicity and mutation induction in Friend mouse erythroleukaemia cells.
Topics: 2-Aminopurine; Animals; Cell Cycle; Cell Line; Cell Survival; Clone Cells; Deoxyribonucleotides; Dru | 1989 |
Quantitation of erythropoietin stimulatory activity using [3H]thymidine uptake by K562 cells.
Topics: Adolescent; Adult; Animals; Cell Line; Child; Child, Preschool; Erythropoietin; Female; Humans; Immu | 1989 |
Characterization of the insulin-like growth factor (IGF) receptor in K562 erythroleukemia cells; evidence for a biological function for the type II IGF receptor.
Topics: Cell Line; DNA; Humans; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Kinetics; Leuke | 1988 |
Effect of aphidicolin on Friend erythroleukemia cell maturation.
Topics: Acetamides; Animals; Aphidicolin; Cell Differentiation; Cell Division; Diterpenes; DNA Polymerase II | 1987 |
Regulation of the activity of heme degradative enzymes in K562 erythroleukemic cells: induction by thymidine.
Topics: Bromobenzenes; Cell Line; Cobalt; Enzyme Induction; Heme; Heme Oxygenase (Decyclizing); Hemin; Human | 1987 |
Synergism between U.V. and thymidine treatments in the induction of cytogenetic damage in wild-type Friend erythroleukaemia cells.
Topics: Animals; Chromosome Aberrations; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Leuk | 1988 |
Effect of fagaronine on cell cycle progression of human erythroleukemia K562 cells.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Benzophenanthridines; Cell Cycle; Cell Line; DNA; Dose | 1988 |
Employment of a [3H]thymidine-incorporation assay to distinguish the effects of different Friend erythroleukemia-inducing retroviruses on erythroid cell proliferation.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Division; Erythrocytes; Erythropoietin; Friend | 1986 |
Supernatants from ethanol-containing macrophage cultures have cytotoxic activity.
Topics: Animals; Cell Adhesion; Cells, Cultured; Cytotoxicity, Immunologic; Dialysis; Ethanol; Hot Temperatu | 1986 |
Localization of AT-rich sequences at the nuclear matrix.
Topics: Animals; Base Sequence; Cell Nucleus; DNA Replication; Leukemia, Erythroblastic, Acute; Mice; Radioi | 1986 |
Demonstration of commitment by K562 human erythroleukemia cells.
Topics: Benzidines; Butyrates; Butyric Acid; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; | 1985 |
Induction of proliferation in vitro of resting human natural killer cells: expression of surface activation antigens.
Topics: Animals; Antigens, Surface; Burkitt Lymphoma; Cell Line; Cytotoxicity, Immunologic; Humans; Interleu | 1985 |
K562 human erythroleukemia cells demonstrate commitment.
Topics: Butyrates; Carbon Dioxide; Cell Differentiation; Cell Line; Hemin; Humans; Leukemia, Erythroblastic, | 1985 |
Haemoglobin synthesis in inducible, uninducible and hybrid Friend cell clones.
Topics: Animals; Biphenyl Compounds; Cell Differentiation; Cell Fusion; Cell Line; Clone Cells; Dimethyl Sul | 1974 |
Cell kinetics of virally-induced leukemias.
Topics: Animals; Autoradiography; Avian Leukosis Virus; Bone Marrow Examination; Carbon Radioisotopes; Cell | 1973 |
Induction of endogenous virus and of thymidine kinase by bromodeoxyuridine in cell cultures transformed by Friend virus.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Transformation, Neoplastic; Enzyme Induction; Friend mur | 1974 |
Decreased proliferative activity of erythroblasts in granulocytic stem cell leukemia.
Topics: Autoradiography; Bone Marrow Cells; DNA, Neoplasm; Erythrocytes; Erythropoiesis; Humans; Leukemia, E | 1971 |
[Radioautographic and cytophotometric studies on the proliferation of erythropoietic precursors in the bone marrow in stem cell leukemias].
Topics: Acetates; Adult; Aged; Autoradiography; Bone Marrow Examination; Cell Nucleus; Culture Techniques; D | 1970 |
Chromosomal abnormality, megaloblastosis, and arrested DNA synthesis in erythroleukaemia.
Topics: Aged; Aneuploidy; Autoradiography; Bone Marrow Cells; Chromosome Aberrations; Chromosomes, Human, 4- | 1969 |
Proliferation and differentiation of hematopoietic cells in hematologic disorders. 3. In vivo radioautographic study of leukemia including erythroleukemia.
Topics: Adult; Female; Hematopoiesis; Humans; Injections, Intravenous; Leukemia; Leukemia, Erythroblastic, A | 1968 |