thymidine has been researched along with Dementia in 4 studies
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "3'-Azido-2',3'-dideoxythymidine (AZT) has been administered to 7 patients with human immunodeficiency virus-associated neurological disease: 3 with dementia, 2 with peripheral neuropathy, 1 with dementia and peripheral neuropathy, and 1 with T-10 paraplegia." | 5.06 | Long-term administration of 3'-azido-2',3'-dideoxythymidine to patients with AIDS-related neurological disease. ( Berg, G; Dalakas, M; Fischl, M; Grafman, J; Klecker, RW; McAtee, N; Perno, CF; Thomas, RV; Wichman, A; Yarchoan, R, 1988) |
| "Mental disturbances associated with acquired immunodeficiency syndrome (AIDS) are related not only to profound psychosocial stress, systemic diseases, and neoplasms or opportunistic infections within the central nervous system (CNS); they are also related to the direct neurotoxicity of the etiologic human immunodeficiency virus (HIV), producing an array of both insidious and acute affective, cognitive, and behavioral dysfunction that can mimic many neuropsychiatric disorders." | 2.37 | AIDS dementia: a review of the literature. ( Marotta, RF; Perry, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kalter, S | 1 |
| Kelly, S | 1 |
| Yarchoan, R | 1 |
| Thomas, RV | 1 |
| Grafman, J | 1 |
| Wichman, A | 1 |
| Dalakas, M | 1 |
| McAtee, N | 1 |
| Berg, G | 1 |
| Fischl, M | 1 |
| Perno, CF | 1 |
| Klecker, RW | 1 |
| Torrence, PF | 1 |
| Kinjo, J | 1 |
| Lesiak, K | 1 |
| Balzarini, J | 1 |
| De Clercq, E | 1 |
| Perry, S | 1 |
| Marotta, RF | 1 |
1 review available for thymidine and Dementia
| Article | Year |
|---|---|
AIDS dementia: a review of the literature.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Brain; Counseling; Dementia; Humans; Nervous S | 1987 |
1 trial available for thymidine and Dementia
| Article | Year |
|---|---|
Long-term administration of 3'-azido-2',3'-dideoxythymidine to patients with AIDS-related neurological disease.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Clinical Trials as Topic; Dementia; Humans; Male; M | 1988 |
2 other studies available for thymidine and Dementia
| Article | Year |
|---|---|
Alzheimer's disease. Evaluation of immunologic indices.
Topics: ABO Blood-Group System; Aged; Alzheimer Disease; Coombs Test; Dementia; Female; Fluorescent Antibody | 1975 |
AIDS dementia: synthesis and properties of a derivative of 3'-azido-3'-deoxythymidine (AZT) that may become 'locked' in the central nervous system.
Topics: Acquired Immunodeficiency Syndrome; Animals; Brain; Cell Line; Chemical Phenomena; Chemistry; Dement | 1988 |