thymidine has been researched along with Deficiency, Vitamin B 12 in 36 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with folate and/or vitamin B12 deficiency, the addition of appropriate vitamins to marrow and lymphocyte cultures enhanced the incorporation of 3H-dU into DNA." | 1.26 | In vitro DNA synthesis by bone marrow cells and PHA-stimulated lymphocytes. Suppression by nonradioactive thymidine of the incorporation of 3H-deoxyuridine into DNA: enhancement of incorporation when inadequate vitamin B12 or folate is corrected. ( Das, KC; Herbert, V; Manusselis, C, 1980) |
| "2." | 1.26 | Synthesis of DNA as shown by the deoxyuridine suppression test is normal in the vitamin B12-deficient fruit bat (Rosettus Aegyptiacus). ( Fernandes-Costa, F; Metz, J; Miller, H, 1980) |
| "Thus, in vitamin B12 deficiency H4PteGlu is not available in sufficient concentration to maintain the de novo synthesis of thymidylate and purines, and accords with the methyl-folate-trap hypothesis." | 1.26 | Cobalamin dependent methionine synthesis and methyl-folate-trap in human vitamin B12 deficiency. ( Sauer, H; Wilmanns, W, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (97.22) | 18.7374 |
| 1990's | 1 (2.78) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burman, JF | 1 |
| Mollin, DL | 1 |
| Wickramasinghe, SN | 7 |
| Saunders, JE | 1 |
| Das, KC | 3 |
| Garewal, G | 1 |
| Mohanty, D | 1 |
| Kano, Y | 1 |
| Sakamoto, S | 1 |
| Hida, K | 1 |
| Suda, K | 1 |
| Takaku, F | 1 |
| Okabe, T | 1 |
| Ishizawa, S | 1 |
| Ishii, T | 1 |
| Kataoka, K | 1 |
| Matsuki, S | 1 |
| Chanarin, I | 2 |
| Deacon, R | 2 |
| Perry, J | 2 |
| Lumb, M | 2 |
| McKenna, B | 1 |
| Weir, DG | 1 |
| Scott, JM | 1 |
| Manusselis, C | 1 |
| Herbert, V | 4 |
| Miller, H | 1 |
| Fernandes-Costa, F | 1 |
| Metz, J | 2 |
| Zittoun, J | 2 |
| Zittoun, R | 2 |
| Marquet, J | 2 |
| Bilski-Pasquier, G | 1 |
| Sultan, C | 1 |
| Van Der Weyden, MB | 3 |
| Sauer, H | 1 |
| Wilmanns, W | 1 |
| Cheng, FW | 1 |
| Shane, B | 1 |
| Stokstad, EL | 1 |
| Herzlich, BC | 1 |
| Ranginwala, M | 1 |
| Nawabi, I | 1 |
| Carmel, R | 1 |
| Karnaze, DS | 1 |
| Chalmers, DG | 2 |
| Cooper, EH | 2 |
| Longland, JE | 1 |
| Koutts, J | 1 |
| Cooper, M | 2 |
| Weinstein, WM | 1 |
| Moffatt, B | 2 |
| Firkin, BG | 1 |
| Tisman, G | 1 |
| Brenner, L | 1 |
| Landureau, JC | 1 |
| Van der Weyden, M | 1 |
| Rother, M | 1 |
| Firkin, B | 1 |
| Müller, D | 1 |
| Hartje, J | 1 |
| Hoffbrand, AV | 1 |
| Yoshida, Y | 1 |
| Todo, A | 2 |
| Shirakawa, S | 1 |
| Wakisaka, G | 1 |
| Uchino, H | 1 |
| Nakao, K | 1 |
| Fujioka, S | 1 |
| Newberne, PM | 1 |
| Rogers, AE | 1 |
| Bailey, C | 1 |
| Young, VR | 1 |
| Waxman, S | 1 |
3 reviews available for thymidine and Deficiency, Vitamin B 12
| Article | Year |
|---|---|
Cobalamin-folate interrelations.
Topics: Anemia, Megaloblastic; Animals; Central Nervous System Diseases; Coenzymes; Folic Acid; Folic Acid D | 1989 |
Kinetics and morphology of haemopoiesis in pernicious anaemia.
Topics: Anemia, Pernicious; Animals; Blood Platelets; Bone Marrow; DNA; Erythrocytes; Erythropoiesis; Hemato | 1972 |
Epithelial cell renewal of the small intestinal mucosa.
Topics: Celiac Disease; Cell Differentiation; Cell Division; Cell Movement; Colchicine; Cytological Techniqu | 1974 |
33 other studies available for thymidine and Deficiency, Vitamin B 12
| Article | Year |
|---|---|
The value of the deoxyuridine suppression test in megaloblastic anaemia.
Topics: Anemia, Megaloblastic; Antimetabolites; Deoxyuridine; Folic Acid Deficiency; Humans; Predictive Valu | 1978 |
Incorporation of radioactive precursors into the nucleic acids of bone marrow cells from patients wtih vitamin B12 or folate deficiency.
Topics: Anemia, Megaloblastic; Bone Marrow; Carbon Radioisotopes; DNA; Folic Acid Deficiency; Humans; In Vit | 1980 |
Derangement of DNA synthesis in erythroleukaemia. Normal deoxyuridine suppression and impaired thymidine incorporation in bone marrow culture.
Topics: Adolescent; Adult; Anemia, Megaloblastic; Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Female; F | 1980 |
5-Methyltetrahydrofolate related enzymes and DNA polymerase alpha activities in bone marrow cells from patients with vitamin B12 deficient megaloblastic anemia.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; 5,10-Methylenetetrahydrofolate Reductase | 1982 |
Erythrocyte aging changes evaluated by the deoxyuridine suppression test.
Topics: Adult; Aged; Bone Marrow; Deoxyuridine; DNA; Erythrocyte Aging; Erythrocyte Indices; Folic Acid Defi | 1982 |
How vitamin B12 acts.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Animals; Folic Acid; Humans; Methionine; Pteroylpolygluta | 1981 |
The induction of functional vitamin B-12 deficiency in rats by exposure to nitrous oxide.
Topics: Animals; Bone Marrow; Deoxyuridine; Disease Models, Animal; DNA; Female; Folic Acid; Formyltetrahydr | 1980 |
In vitro DNA synthesis by bone marrow cells and PHA-stimulated lymphocytes. Suppression by nonradioactive thymidine of the incorporation of 3H-deoxyuridine into DNA: enhancement of incorporation when inadequate vitamin B12 or folate is corrected.
Topics: Bone Marrow; Cells, Cultured; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; Lymphocy | 1980 |
Synthesis of DNA as shown by the deoxyuridine suppression test is normal in the vitamin B12-deficient fruit bat (Rosettus Aegyptiacus).
Topics: Animals; Bone Marrow; Cells, Cultured; Chiroptera; Deoxyuridine; DNA; Folic Acid; Lymphocytes; Metho | 1980 |
[Anaemia induced by vitamin B12 or folate deficiency: diagnostic value of the "dU suppression" test (author's transl)].
Topics: Anemia; Anemia, Macrocytic; Anemia, Megaloblastic; Anemia, Sideroblastic; Bone Marrow; Deoxyuridine; | 1978 |
Deoxyuridine metabolism in human megaloblastic marrow cells.
Topics: Anemia, Macrocytic; Anemia, Megaloblastic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid De | 1979 |
Effect of folate and cobalamin compounds on the deoxyuridine suppression test in vitamin B12 and folate deficiency.
Topics: Deoxyuridine; Folic Acid; Folic Acid Deficiency; Humans; Methotrexate; Thymidine; Vitamin B 12; Vita | 1978 |
Cobalamin dependent methionine synthesis and methyl-folate-trap in human vitamin B12 deficiency.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Bone Marrow; Bone Marrow Cells; Deoxyurid | 1977 |
The anti-folate effect of methionine on bone marrow of normal and vitamin B12 deficient rats.
Topics: Animals; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Antagonists; Homocysteine; Liver; Ma | 1975 |
Synergy of inhibition of DNA synthesis in human bone marrow by azidothymidine plus deficiency of folate and/or vitamin B12?
Topics: Bone Marrow; Deoxyuridine; DNA; Folic Acid Deficiency; Humans; Pyrimidines; Tetrahydrofolates; Thymi | 1990 |
The deoxyuridine suppression test identifies subtle cobalamin deficiency in patients without typical megaloblastic anemia.
Topics: Aged; Bone Marrow; Bone Marrow Examination; Deoxyuridine; DNA; Female; Humans; In Vitro Techniques; | 1985 |
Arrest of cell proliferation and protein synthesis in megaloblasts of pernicious anaemia.
Topics: Anemia, Pernicious; Autoradiography; Blood Proteins; Bone Marrow Examination; Carbon Isotopes; DNA; | 1969 |
Rate of incorporation of tritiated thymidine into DNA of normoblastic and megaloblastic bone marrow cells in vitro.
Topics: Alcoholism; Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Bone Marrow Cells; Deoxyuridine; D | 1974 |
Effect ot trimethoprim on folate metabolism in human bone marrow.
Topics: Adult; Anemia, Macrocytic; Anti-Infective Agents; Bone Marrow; Culture Techniques; Deoxyuridine; Dep | 1973 |
DNA synthesis during human eosinopoiesis.
Topics: Anemia, Macrocytic; Autoradiography; Bone Marrow; Bone Marrow Cells; DNA; Eosinophilia; Eosinophils; | 1972 |
Defective DNA synthesis in human megaloblastic bone marrow: effects of hydroxy-B 12 5'-deoxyadenosyl-B 12 and methyl-B 12 .
Topics: Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow; Bone Marrow Cells; Cells, Cultured; Deoxyuridin | 1973 |
The dU suppression test using 125 I-UdR to define biochemical megaloblastosis.
Topics: Anemia, Macrocytic; Bone Marrow; Deoxyuridine; DNA; Folic Acid; Folic Acid Deficiency; Humans; In Vi | 1973 |
[Biological role of vitamin B 12: analysis of strict vitamin requirement of cell line of insects in vitro].
Topics: Aminopterin; Cell Division; Cell Line; Coleoptera; Culture Techniques; Folic Acid; Folic Acid Defici | 1970 |
Observations on cell proliferation in human myelocytes.
Topics: Anemia, Sideroblastic; Autoradiography; Bone Marrow; Bone Marrow Cells; Cell Division; Cell Nucleus; | 1971 |
Megaloblastic maturation masked by iron deficiency: a biochemical basis.
Topics: Anemia, Hypochromic; Anemia, Macrocytic; Bone Marrow; Culture Techniques; Deferoxamine; Deoxyuridine | 1972 |
[Formation and fate of "giant metamyelocytes" in megaloblastic anemias].
Topics: Aged; Anemia, Macrocytic; Autoradiography; Cell Nucleus; DNA; Erythropoiesis; Female; Humans; Leukoc | 1969 |
Lymphocyte transformation in megaloblastic anaemia: morphology and DNA synthesis.
Topics: Anemia, Macrocytic; Anemia, Pernicious; Chromosomes; Culture Techniques; Deoxyuridine; DNA; Folic Ac | 1970 |
Proliferation of megaloblasts in pernicious anemia as observed from nucleic acid metabolism.
Topics: Anemia, Macrocytic; Anemia, Pernicious; Autoradiography; Bone Marrow Cells; Densitometry; DNA; Eryth | 1968 |
A study of erythropoiesis by combined morphologic, quantitative cytochemical and autoradiographic methods. Normal human bone marrow, vitamin B12 deficiency and iron deficiency anemia.
Topics: Anemia, Hypochromic; Anemia, Macrocytic; Anemia, Pernicious; Autoradiography; Bone Marrow; Bone Marr | 1968 |
Thymidine kinase activity in the human bone marrow from various blood diseases.
Topics: Anemia; Bone Marrow; Bone Marrow Cells; Chromatography, Paper; Humans; Leukemia; Thymidine; Thymidin | 1968 |
Proliferation and differentiation of hematopoietic cells in hematologic disorders. 1. In vitro radioautographic study of megaloblast in vitamin B12 and folic acid deficiency.
Topics: Adult; Aged; Anemia, Macrocytic; Culture Techniques; Erythrocytes; Folic Acid Deficiency; Hematopoie | 1968 |
The induction of liver cirrhosis in rats by purified amino acid diets.
Topics: Amino Acids; Animals; Body Weight; Cholesterol; Choline Deficiency; Deficiency Diseases; Diet; Dieta | 1969 |
Defective DNA synthesis in human megaloblastic bone marrow: effects of homocysteine and methionine.
Topics: Anemia; Anemia, Macrocytic; Anemia, Pernicious; Bone Marrow; Deoxyuridine; DNA; Folic Acid Deficienc | 1969 |