thymidine has been researched along with Colorectal Cancer in 51 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "A novel sequential administration schedule of PALA (N-phosphonoacetyl-L-aspartate) and thymidine to enhance the cytotoxic effect of 5-fluorouracil (5FU) was tested in 36 patients with advanced gastric cancer and 21 patients with advanced poorly differentiated (anaplastic) colorectal cancer." | 9.06 | A clinical trial of biochemical modulation of 5-fluorouracil with N-phosphonoacetyl-L-aspartate and thymidine in advanced gastric and anaplastic colorectal cancer. ( Goldberg, RM; Krook, JE; Kugler, JW; Laurie, JA; Moertel, CG; O'Connell, MJ; Pfeifle, DM; Rubin, J; Wieand, HS; Windschitl, HE, 1990) |
| " The current study was undertaken to compare AgNOR values in colorectal cancers with two better established methods for investigating cell proliferation such as bromodeoxyuridine (BrdUrd) and 3[H]-thymidine (3[H]dT) labelling indices (LIs)." | 7.69 | Argyrophilic nucleolar organizer regions and bromodeoxyuridine and 3[H]-thymidine labelling indices in colorectal cancer. ( DiGregorio, C; Fante, R; Losi, L; Migaldi, M; Pedroni, M; Ponz de Leon, M; Roncucci, L; Trentini, GP, 1995) |
| "Samples of normal rectal mucosa from 26 patients at increased risk for colorectal cancer (22 patients with adenoma, three with adenocarcinoma of the large bowel, and one with longstanding ulcerative colitis) were examined by means of in vitro labeling with tritiated thymidine and flow cytometry." | 7.69 | Flow cytometry and in vitro tritiated thymidine labeling in normal rectal mucosa of patients at high risk of colorectal cancer. ( Barbara, L; Biasco, G; Brandi, G; Facchini, A; Lalli, E; Paganelli, GM; Santucci, R, 1994) |
| "A human tumour cloning assay (HTCA) has been performed on 191 samples of gastric and 152 samples of colorectal cancers, and a thymidine incorporation assay (TIA) on 178 samples of gastric and 109 samples of colorectal cancers." | 7.68 | In vitro growth ability and chemosensitivity of gastric and colorectal cancer cells assessed with the human tumour clonogenic assay and the thymidine incorporation assay. ( Dohmae, N; Morimoto, H; Muraoka, R; Shimomatsuya, T; Takahashi, K; Tanigawa, N, 1992) |
| "A novel sequential administration schedule of PALA (N-phosphonoacetyl-L-aspartate) and thymidine to enhance the cytotoxic effect of 5-fluorouracil (5FU) was tested in 36 patients with advanced gastric cancer and 21 patients with advanced poorly differentiated (anaplastic) colorectal cancer." | 5.06 | A clinical trial of biochemical modulation of 5-fluorouracil with N-phosphonoacetyl-L-aspartate and thymidine in advanced gastric and anaplastic colorectal cancer. ( Goldberg, RM; Krook, JE; Kugler, JW; Laurie, JA; Moertel, CG; O'Connell, MJ; Pfeifle, DM; Rubin, J; Wieand, HS; Windschitl, HE, 1990) |
| " In the present study, we analyzed the potential relevance of fractional incorporation (FI) of a nucleotide precursor (3H-thymidine, 3H-dT) into DNA of tumor cells, determined on the primary tumor, on long-term clinical outcome of a series of patients with colorectal cancer." | 3.70 | Nucleotide fractional incorporation: a simple metabolic feature potentially related to clinical outcome in colorectal cancer patients. ( Aronne, T; Caliò, E; Costa, A; De Luca, A; Franchi, F; Izzo, L; Seminara, P; Truglia, S, 1998) |
| " The current study was undertaken to compare AgNOR values in colorectal cancers with two better established methods for investigating cell proliferation such as bromodeoxyuridine (BrdUrd) and 3[H]-thymidine (3[H]dT) labelling indices (LIs)." | 3.69 | Argyrophilic nucleolar organizer regions and bromodeoxyuridine and 3[H]-thymidine labelling indices in colorectal cancer. ( DiGregorio, C; Fante, R; Losi, L; Migaldi, M; Pedroni, M; Ponz de Leon, M; Roncucci, L; Trentini, GP, 1995) |
| "Measurement of proliferation rates by the more standard in vitro uptake techniques of [3H]thymidine and 5'-bromo-2'-deoxyuridine (BrdUrd) labeling indices (LIs) were compared to proliferating cell nuclear antigen (PCNA) in rectal mucosal biopsies from 16 subjects with resected colorectal cancer and 14 normal age-matched controls." | 3.69 | Comparison of proliferating cell nuclear antigen versus the more standard measures of rectal mucosal proliferation rates in subjects with a history of colorectal cancer and normal age-matched controls. ( Alberts, D; Earnest, D; Einspahr, J; Grogan, T; Hixson, L; Powell, M; Ritchie, J; Roe, D; Xie, T, 1995) |
| "Samples of normal rectal mucosa from 26 patients at increased risk for colorectal cancer (22 patients with adenoma, three with adenocarcinoma of the large bowel, and one with longstanding ulcerative colitis) were examined by means of in vitro labeling with tritiated thymidine and flow cytometry." | 3.69 | Flow cytometry and in vitro tritiated thymidine labeling in normal rectal mucosa of patients at high risk of colorectal cancer. ( Barbara, L; Biasco, G; Brandi, G; Facchini, A; Lalli, E; Paganelli, GM; Santucci, R, 1994) |
| "Two cell-kinetic parameters, the thymidine labeling index (T-LI) and the mitotic index (MI) were determined for a prospective series of 74 primary colorectal cancers." | 3.69 | Thymidine labeling index in colorectal carcinoma: relation to clinicopathological parameters and to mitotic index. ( Biondo, B; Lavezzi, AM; Matturri, L, 1997) |
| "A human tumour cloning assay (HTCA) has been performed on 191 samples of gastric and 152 samples of colorectal cancers, and a thymidine incorporation assay (TIA) on 178 samples of gastric and 109 samples of colorectal cancers." | 3.68 | In vitro growth ability and chemosensitivity of gastric and colorectal cancer cells assessed with the human tumour clonogenic assay and the thymidine incorporation assay. ( Dohmae, N; Morimoto, H; Muraoka, R; Shimomatsuya, T; Takahashi, K; Tanigawa, N, 1992) |
| "Seventy-five patients with colorectal cancer were randomized to receive octreotide (200 micrograms daily) in the 2 weeks before surgery or the usual medications." | 2.68 | Inhibition of tumor cell kinetics and serum insulin growth factor I levels by octreotide in colorectal cancer patients. ( Cascinu, S; Catalano, G; Del Ferro, E; Foglietti, G; Ghiselli, R; Grianti, C; Ligi, M; Lungarotti, F; Saba, V, 1997) |
| "Subjects at high risk for colon cancer received different doses of fish oil on a 30-day randomized double-blind trial to evaluate the chemopreventive effect of n-3 fatty acids against colorectal cancer." | 2.67 | n-3 PUFA and alpha-tocopherol control of tumor cell proliferation. ( Anti, M; Armelao, F; Bartoli, GM; Franceschelli, P; Luberto, C; Marra, G; Palozza, P; Piccioni, E; Sgarlata, E, 1993) |
| " We performed pharmacokinetic measurements with [(14)C]FMAU and PET studies with [(11)C]FMAU using rats bearing several different syngeneic tumors." | 1.32 | Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats. ( Alauddin, MM; Bading, JR; Bathija, P; Conti, PS; Fissekis, JD; Koda, RT; Koszalka, GW; Shahinian, AH; Vail, A, 2004) |
| "Membrane preparations from a resected colorectal cancer contained a 30-kilodalton PNA-binding glycoprotein similar to that in HT29 cells." | 1.29 | Proliferative responses of HT29 and Caco2 human colorectal cancer cells to a panel of lectins. ( Parker, N; Rhodes, EG; Rhodes, JM; Ryder, SD; Smith, JA, 1994) |
| "Bromodeoxyuridine (BUdR) is a non-radioactive thymidine analogue which is incorporated into DNA during the S-phase of cycling cells." | 1.28 | Cell kinetics evaluation of colorectal tumors after in vivo administration of bromodeoxyuridine. ( Bormioli, ML; Di Gregorio, C; Fante, R; Losi, L; Pedroni, M; Petocchi, B; Ponz de Leon, M; Roncucci, L; Sassatelli, R; Scalmati, A, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.96) | 18.7374 |
| 1990's | 28 (54.90) | 18.2507 |
| 2000's | 15 (29.41) | 29.6817 |
| 2010's | 6 (11.76) | 24.3611 |
| 2020's | 1 (1.96) | 2.80 |
| Authors | Studies |
|---|---|
| Virgilio, A | 1 |
| Benigno, D | 1 |
| Pecoraro, A | 1 |
| Russo, A | 1 |
| Russo, G | 1 |
| Esposito, V | 1 |
| Galeone, A | 1 |
| Schelhaas, S | 1 |
| Wachsmuth, L | 1 |
| Hermann, S | 1 |
| Rieder, N | 1 |
| Heller, A | 1 |
| Heinzmann, K | 1 |
| Honess, DJ | 1 |
| Smith, DM | 1 |
| Fricke, IB | 1 |
| Just, N | 1 |
| Doblas, S | 1 |
| Sinkus, R | 1 |
| Döring, C | 1 |
| Schäfers, KP | 1 |
| Griffiths, JR | 1 |
| Faber, C | 1 |
| Schneider, R | 1 |
| Aboagye, EO | 1 |
| Jacobs, AH | 1 |
| Witherspoon, M | 1 |
| Chen, Q | 1 |
| Kopelovich, L | 1 |
| Gross, SS | 1 |
| Lipkin, SM | 1 |
| Casero, RA | 1 |
| Rapic, S | 1 |
| Vangestel, C | 1 |
| Verhaeghe, J | 1 |
| Thomae, D | 1 |
| Pauwels, P | 1 |
| Van den Wyngaert, T | 1 |
| Staelens, S | 1 |
| Stroobants, S | 1 |
| Manning, HC | 1 |
| Merchant, NB | 1 |
| Foutch, AC | 1 |
| Virostko, JM | 1 |
| Wyatt, SK | 1 |
| Shah, C | 1 |
| McKinley, ET | 1 |
| Xie, J | 1 |
| Mutic, NJ | 1 |
| Washington, MK | 1 |
| LaFleur, B | 1 |
| Tantawy, MN | 1 |
| Peterson, TE | 1 |
| Ansari, MS | 1 |
| Baldwin, RM | 1 |
| Rothenberg, ML | 1 |
| Bornhop, DJ | 1 |
| Gore, JC | 1 |
| Coffey, RJ | 1 |
| Brody, JR | 1 |
| Hucl, T | 1 |
| Costantino, CL | 1 |
| Eshleman, JR | 1 |
| Gallmeier, E | 1 |
| Zhu, H | 1 |
| van der Heijden, MS | 1 |
| Winter, JM | 1 |
| Wikiewicz, AK | 1 |
| Yeo, CJ | 1 |
| Kern, SE | 1 |
| Griffiths, M | 1 |
| Sundaram, H | 1 |
| Gagou, ME | 1 |
| Ganesh, A | 1 |
| Thompson, R | 1 |
| Phear, G | 1 |
| Sanders, C | 1 |
| Meuth, M | 1 |
| Bading, JR | 1 |
| Shahinian, AH | 1 |
| Vail, A | 1 |
| Bathija, P | 1 |
| Koszalka, GW | 1 |
| Koda, RT | 1 |
| Alauddin, MM | 1 |
| Fissekis, JD | 1 |
| Conti, PS | 1 |
| Issa, W | 1 |
| Tochon-Danguy, HJ | 1 |
| Lambert, J | 1 |
| Sachinidis, JI | 1 |
| Ackermann, U | 1 |
| Liu, Z | 1 |
| Scott, AM | 1 |
| Schmittgen, TD | 1 |
| Gissel, KA | 1 |
| Zakrajsek, BA | 1 |
| Lawrence, BP | 1 |
| Liu, Q | 1 |
| Jupe, ER | 1 |
| Lerner, MR | 1 |
| Do, SV | 1 |
| Brackett, DJ | 1 |
| Emura, T | 1 |
| Suzuki, N | 1 |
| Fujioka, A | 1 |
| Ohshimo, H | 1 |
| Fukushima, M | 1 |
| Xie, JT | 1 |
| Wang, CZ | 1 |
| Wicks, S | 1 |
| Yin, JJ | 1 |
| Kong, J | 1 |
| Li, J | 1 |
| Li, YC | 1 |
| Yuan, CS | 1 |
| Graham-Cole, CL | 1 |
| Thomas, HD | 1 |
| Taylor, GA | 1 |
| Newell, DR | 1 |
| Melton, RG | 1 |
| Hesp, R | 1 |
| Boddy, AV | 1 |
| Li, KM | 1 |
| Rivory, LP | 1 |
| Hoskins, J | 1 |
| Sharma, R | 1 |
| Clarke, SJ | 1 |
| Gessi, S | 1 |
| Merighi, S | 1 |
| Varani, K | 1 |
| Cattabriga, E | 1 |
| Benini, A | 1 |
| Mirandola, P | 1 |
| Leung, E | 1 |
| Mac Lennan, S | 1 |
| Feo, C | 1 |
| Baraldi, S | 1 |
| Borea, PA | 1 |
| Losi, L | 2 |
| DiGregorio, C | 1 |
| Fante, R | 3 |
| Migaldi, M | 1 |
| Roncucci, L | 3 |
| Pedroni, M | 2 |
| Ponz de Leon, M | 3 |
| Trentini, GP | 1 |
| Einspahr, J | 2 |
| Alberts, D | 1 |
| Xie, T | 1 |
| Ritchie, J | 1 |
| Earnest, D | 2 |
| Hixson, L | 2 |
| Powell, M | 2 |
| Roe, D | 2 |
| Grogan, T | 1 |
| Alberts, DS | 1 |
| Aickin, M | 1 |
| Hennigan, TW | 1 |
| Allen-Mersh, TG | 1 |
| Park, KG | 1 |
| Heys, SD | 1 |
| McNurlan, MA | 1 |
| Garlick, PJ | 1 |
| Eremin, O | 1 |
| Tanigawa, N | 2 |
| Masuda, Y | 1 |
| Muraoka, R | 2 |
| Tanaka, T | 1 |
| Bartoli, GM | 1 |
| Palozza, P | 1 |
| Marra, G | 1 |
| Armelao, F | 1 |
| Franceschelli, P | 1 |
| Luberto, C | 1 |
| Sgarlata, E | 1 |
| Piccioni, E | 1 |
| Anti, M | 1 |
| Ryder, SD | 1 |
| Smith, JA | 1 |
| Rhodes, EG | 1 |
| Parker, N | 1 |
| Rhodes, JM | 1 |
| Paganelli, GM | 1 |
| Lalli, E | 1 |
| Facchini, A | 1 |
| Biasco, G | 1 |
| Santucci, R | 1 |
| Brandi, G | 1 |
| Barbara, L | 1 |
| Watson, SA | 1 |
| Clifford, T | 1 |
| Sykes, RE | 1 |
| Robinson, E | 1 |
| Steele, RJ | 1 |
| Velázquez, OC | 1 |
| Jabbar, A | 1 |
| DeMatteo, RP | 1 |
| Rombeau, JL | 1 |
| Cascinu, S | 1 |
| Del Ferro, E | 1 |
| Grianti, C | 1 |
| Ligi, M | 1 |
| Ghiselli, R | 1 |
| Foglietti, G | 1 |
| Saba, V | 1 |
| Lungarotti, F | 1 |
| Catalano, G | 1 |
| Matturri, L | 2 |
| Biondo, B | 1 |
| Lavezzi, AM | 2 |
| Frenkel, K | 1 |
| Karkoszka, J | 1 |
| Glassman, T | 1 |
| Dubin, N | 1 |
| Toniolo, P | 1 |
| Taioli, E | 1 |
| Mooney, LA | 1 |
| Kato, I | 1 |
| Ottaviani, G | 1 |
| De Ruberto, F | 1 |
| Fichera, G | 1 |
| Franchi, F | 3 |
| Seminara, P | 3 |
| Izzo, L | 1 |
| De Luca, A | 1 |
| Truglia, S | 1 |
| Aronne, T | 1 |
| Caliò, E | 1 |
| Costa, A | 2 |
| Hofer, H | 1 |
| Ho, Gm | 1 |
| Peterlik, M | 1 |
| Uskokovic, MR | 1 |
| Lee, JK | 1 |
| White, MC | 1 |
| Posner, GH | 1 |
| Cross, HS | 1 |
| Lehman, NL | 1 |
| Danenberg, PV | 1 |
| Johnson, FE | 1 |
| Zhou, M | 1 |
| Collins, BT | 1 |
| Huang, JS | 1 |
| Jeanteur, P | 1 |
| Chou, LF | 1 |
| Chou, WG | 1 |
| Przybylowska, K | 1 |
| Smolarczyk, K | 1 |
| Blasiak, J | 1 |
| Kulig, A | 1 |
| Romanowicz-Makowska, H | 1 |
| Dziki, A | 1 |
| Ulanska, J | 1 |
| Pander, B | 1 |
| Visvikis, D | 1 |
| Francis, DL | 1 |
| Costa, DC | 1 |
| Mulligan, R | 1 |
| Townsend, C | 1 |
| Arulampalam, TH | 1 |
| Islam, MS | 1 |
| Taylor, I | 1 |
| Ell, PJ | 1 |
| Kashtan, H | 1 |
| Stern, HS | 1 |
| Scalmati, A | 2 |
| Bormioli, ML | 1 |
| Sassatelli, R | 1 |
| Di Gregorio, C | 2 |
| Petocchi, B | 1 |
| Morimoto, H | 2 |
| Dohmae, N | 1 |
| Shimomatsuya, T | 1 |
| Takahashi, K | 1 |
| Giannarelli, D | 1 |
| Konovalova, N | 1 |
| Lanza, G | 1 |
| Faranda, A | 1 |
| Colella, G | 2 |
| Silvestrini, R | 2 |
| Rossi-Fanelli, F | 1 |
| Cascino, A | 1 |
| Barone, C | 1 |
| Scucchi, L | 1 |
| Ito, M | 1 |
| Yoshida, K | 1 |
| Kyo, E | 1 |
| Ayhan, A | 1 |
| Nakayama, H | 1 |
| Yasui, W | 1 |
| Ito, H | 1 |
| Tahara, E | 1 |
| Nio, Y | 1 |
| Imai, S | 1 |
| Shiraishi, T | 1 |
| Tsubono, M | 1 |
| Tseng, CC | 1 |
| Tobe, T | 1 |
| Windschitl, HE | 1 |
| O'Connell, MJ | 1 |
| Wieand, HS | 1 |
| Krook, JE | 1 |
| Rubin, J | 1 |
| Moertel, CG | 1 |
| Kugler, JW | 1 |
| Pfeifle, DM | 1 |
| Goldberg, RM | 1 |
| Laurie, JA | 1 |
| Villa, R | 1 |
| Zaffaroni, N | 1 |
| Giuliani, F | 1 |
| Sanfilippo, O | 1 |
| Sakamoto, S | 1 |
| Kawachi, Y | 1 |
| Tsukada, K | 1 |
| Mishima, Y | 1 |
| Okamoto, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase II Trial of TAS-102 in Patients With Advanced, Refractory Pancreatic Adenocarcinoma[NCT04923529] | Phase 2 | 28 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thymidine and Colorectal Cancer
| Article | Year |
|---|---|
Colonic proliferation and colon cancer risk. A review of clinical studies.
Topics: Biomarkers, Tumor; Breath Tests; Calcium, Dietary; Colorectal Neoplasms; Diet; Dietary Fats; Dietary | 1992 |
5 trials available for thymidine and Colorectal Cancer
| Article | Year |
|---|---|
Validation of proliferation indices as surrogate endpoint biomarkers.
Topics: Adenoma; Adult; Autoradiography; Biomarkers; Biopsy; Bromodeoxyuridine; Cell Division; Colorectal Ne | 1994 |
n-3 PUFA and alpha-tocopherol control of tumor cell proliferation.
Topics: Adenomatous Polyposis Coli; Autoradiography; Cell Division; Colonic Neoplasms; Colorectal Neoplasms; | 1993 |
Inhibition of tumor cell kinetics and serum insulin growth factor I levels by octreotide in colorectal cancer patients.
Topics: Adult; Aged; Antineoplastic Agents, Hormonal; Cell Cycle; Colorectal Neoplasms; Epidermal Growth Fac | 1997 |
Cell kinetics of gastrointestinal tumors after different nutritional regimens. A preliminary report.
Topics: Aged; Cell Division; Colorectal Neoplasms; Digestive System Neoplasms; Esophageal Neoplasms; Female; | 1991 |
A clinical trial of biochemical modulation of 5-fluorouracil with N-phosphonoacetyl-L-aspartate and thymidine in advanced gastric and anaplastic colorectal cancer.
Topics: Adult; Aged; Aspartic Acid; Clinical Trials as Topic; Colorectal Neoplasms; Drug Evaluation; Drug Sy | 1990 |
45 other studies available for thymidine and Colorectal Cancer
| Article | Year |
|---|---|
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG
Topics: Amino Acid Substitution; Antineoplastic Agents; Aptamers, Nucleotide; Cell Line, Tumor; Cell Movemen | 2021 |
Thymidine Metabolism as a Confounding Factor for 3'-Deoxy-3'-
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Artifacts; Biological Transport; Cell Trans | 2018 |
Unbiased metabolite profiling indicates that a diminished thymidine pool is the underlying mechanism of colon cancer chemoprevention by alpha-difluoromethylornithine.
Topics: Animals; Cell Line, Tumor; Chemoprevention; Colorectal Neoplasms; Eflornithine; Enzyme Inhibitors; H | 2013 |
Say what? The activity of the polyamine biosynthesis inhibitor difluoromethylornithine in chemoprevention is a result of reduced thymidine pools?
Topics: Animals; Colorectal Neoplasms; Eflornithine; Enzyme Inhibitors; Humans; Thymidine | 2013 |
Evaluation of [
Topics: Adenosine Triphosphate; Animals; Biomarkers, Tumor; Cell Line, Tumor; Colorectal Neoplasms; Dideoxyn | 2017 |
Molecular imaging of therapeutic response to epidermal growth factor receptor blockade in colorectal cancer.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cetuximab | 2008 |
Limits to thymidylate synthase and TP53 genes as predictive determinants for fluoropyrimidine sensitivity and further evidence for RNA-based toxicity as a major influence.
Topics: Alleles; Antimetabolites, Antineoplastic; Base Sequence; Cell Line, Tumor; Colorectal Neoplasms; Flu | 2009 |
Drug design and testing: profiling of antiproliferative agents for cancer therapy using a cell-based methyl-[3H]-thymidine incorporation assay.
Topics: Antineoplastic Agents; Aurora Kinases; Cell Count; Cell Line, Tumor; Cell Proliferation; Cell Surviv | 2011 |
Suppression of apoptosis by PIF1 helicase in human tumor cells.
Topics: Apoptosis; Caspase 3; Checkpoint Kinase 1; Colorectal Neoplasms; DNA Helicases; DNA Replication; G1 | 2011 |
Pharmacokinetics of the thymidine analog 2'-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil (FMAU) in tumor-bearing rats.
Topics: Adenocarcinoma; Animals; Arabinofuranosyluracil; Carbon Radioisotopes; Cell Line, Tumor; Colorectal | 2004 |
Synthesis and evaluation of a thymidine analog for positron emission tomography study of tumor DNA proliferation in vivo.
Topics: Animals; Cell Line, Tumor; Colorectal Neoplasms; DNA, Neoplasm; Drug Stability; Fluorine Radioisotop | 2004 |
Diverse gene expression pattern during 5-fluorouridine-induced apoptosis.
Topics: Analysis of Variance; Apoptosis; Cell Survival; Cluster Analysis; Colorectal Neoplasms; Flow Cytomet | 2005 |
Potentiation of the antitumor activity of alpha, alpha, alpha-trifluorothymidine by the co-administration of an inhibitor of thymidine phosphorylase at a suitable molar ratio in vivo.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Body Weight; Cell Line, Tumor; Colorectal N | 2005 |
Ganoderma lucidum extract inhibits proliferation of SW 480 human colorectal cancer cells.
Topics: Cell Division; Cell Line, Tumor; Colorectal Neoplasms; DNA Replication; Humans; Phytotherapy; Plant | 2006 |
An evaluation of thymidine phosphorylase as a means of preventing thymidine rescue from the thymidylate synthase inhibitor raltitrexed.
Topics: Animals; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Carcinoembryonic Antigen; Cell Lin | 2007 |
Altered deoxyuridine and thymidine in plasma following capecitabine treatment in colorectal cancer patients.
Topics: Antimetabolites, Antineoplastic; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Deoxyuridine; Fe | 2007 |
Adenosine receptors in colon carcinoma tissues and colon tumoral cell lines: focus on the A(3) adenosine subtype.
Topics: Adenocarcinoma; Adenosine; Blotting, Western; Caco-2 Cells; Cell Division; Colorectal Neoplasms; Cyc | 2007 |
Argyrophilic nucleolar organizer regions and bromodeoxyuridine and 3[H]-thymidine labelling indices in colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Bromodeoxyuridine; Cell Division; Colorectal Neoplasms; Female; Huma | 1995 |
Comparison of proliferating cell nuclear antigen versus the more standard measures of rectal mucosal proliferation rates in subjects with a history of colorectal cancer and normal age-matched controls.
Topics: Adult; Aged; Autoradiography; Bromodeoxyuridine; Case-Control Studies; Cell Division; Colorectal Neo | 1995 |
The influence of fibroblasts on the growth of human colorectal carcinoma xenografts.
Topics: Animals; Carcinoma; Cell Division; Colorectal Neoplasms; Fibroblasts; Humans; Mice; Mice, Nude; Neop | 1994 |
Lymphocyte protein synthesis in vivo: a measure of activation.
Topics: Adult; Carbon Isotopes; Colorectal Neoplasms; Humans; Immunophenotyping; Interleukin-2; Leucine; Liv | 1994 |
Prognostic significance of in vitro thymidine uptake in patients with colorectal carcinoma.
Topics: Adenocarcinoma; Aged; Analysis of Variance; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; | 1994 |
Proliferative responses of HT29 and Caco2 human colorectal cancer cells to a panel of lectins.
Topics: Carcinoma; Cell Count; Cell Division; Cell Membrane; Colorectal Neoplasms; Fluorescein-5-isothiocyan | 1994 |
Flow cytometry and in vitro tritiated thymidine labeling in normal rectal mucosa of patients at high risk of colorectal cancer.
Topics: Adenocarcinoma; Aged; Aneuploidy; Cell Division; Colitis, Ulcerative; Colorectal Neoplasms; Female; | 1994 |
Gastrin sensitivity of primary human colorectal cancer: the effect of gastrin receptor antagonism.
Topics: Amino Acids; Cell Division; Colorectal Neoplasms; Gastrins; Hormone Antagonists; Hormones; Humans; I | 1995 |
Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Colorectal Neoplasms; Liver Neoplasms; Mevalonic Ac | 1996 |
Thymidine labeling index in colorectal carcinoma: relation to clinicopathological parameters and to mitotic index.
Topics: Adult; Aged; Aged, 80 and over; Cell Division; Colorectal Neoplasms; Female; Humans; Male; Middle Ag | 1997 |
Serum autoantibodies recognizing 5-hydroxymethyl-2'-deoxyuridine, an oxidized DNA base, as biomarkers of cancer risk in women.
Topics: Adult; Age Factors; Aged; Autoantibodies; Biomarkers, Tumor; Breast Neoplasms; Colorectal Neoplasms; | 1998 |
The prognostic value of cell proliferation in colorectal adenomas assessed with tritiated thymidine and anti-proliferating cell nuclear antigen.
Topics: Adenomatous Polyps; Adult; Aged; Aged, 80 and over; Autoradiography; Cell Division; Colonoscopy; Col | 1999 |
Nucleotide fractional incorporation: a simple metabolic feature potentially related to clinical outcome in colorectal cancer patients.
Topics: Colorectal Neoplasms; Combined Modality Therapy; DNA Replication; DNA, Neoplasm; Humans; Prognosis; | 1998 |
Biological effects of 1alpha-hydroxy- and 1beta-(hydroxymethyl)-vitamin D compounds relevant for potential colorectal cancer therapy.
Topics: Acid Phosphatase; Animals; Antineoplastic Agents; Blotting, Western; Bone Marrow; Caco-2 Cells; Calc | 1999 |
Modulation of RTX cytotoxicity by thymidine and dipyridamole in vitro: implications for chemotherapy.
Topics: Antimetabolites, Antineoplastic; Colorectal Neoplasms; Dipyridamole; Dose-Response Relationship, Dru | 2000 |
Mechanical deformation induces proliferation of human colorectal carcinoma cells.
Topics: Cell Division; Colorectal Neoplasms; Humans; Immunohistochemistry; Plasminogen Activator Inhibitor 1 | 2000 |
[Nutrition, genetic polymorphism, and cancer].
Topics: Colorectal Neoplasms; DNA; DNA Repair; Folic Acid; Genotype; Humans; Methylenetetrahydrofolate Reduc | 2000 |
Dna-end binding activity of Ku in synchronized cells.
Topics: Animals; Antigens, Nuclear; Antineoplastic Agents; Blood Proteins; Cell Separation; CHO Cells; Color | 1999 |
A C/T polymorphism in the urokinase-type plasminogen activator gene in colorectal cancer.
Topics: Adult; Aged; Colorectal Neoplasms; Cytosine; DNA Primers; DNA, Neoplasm; Female; Gene Frequency; Gen | 2001 |
Glucose utilisation and cell proliferation in colorectal cancer.
Topics: Cell Division; Colorectal Neoplasms; Fluorodeoxyglucose F18; Glucose; Radionuclide Imaging; Radiopha | 2002 |
Cell kinetics evaluation of colorectal tumors after in vivo administration of bromodeoxyuridine.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Bromodeoxyuridine; Cell Division; Colorectal N | 1992 |
In vitro growth ability and chemosensitivity of gastric and colorectal cancer cells assessed with the human tumour clonogenic assay and the thymidine incorporation assay.
Topics: Colorectal Neoplasms; Drug Screening Assays, Antitumor; Humans; Stomach Neoplasms; Thymidine; Tumor | 1992 |
Fractional incorporation of radionucleotides, a marker of in vitro tumor cell chemosensitivity in colorectal cancer.
Topics: Antineoplastic Agents; Colorectal Neoplasms; Daunorubicin; DNA, Neoplasm; Doxorubicin; Humans; In Vi | 1991 |
Reliability of 3H-thymidine labeling index: cell proliferation of colorectal carcinoma in three different centers.
Topics: Adult; Aged; Aged, 80 and over; Autoradiography; Biomarkers, Tumor; Cell Division; Colorectal Neopla | 1991 |
Expression of several growth factors and their receptor genes in human colon carcinomas.
Topics: Antibodies, Monoclonal; Blotting, Northern; Colorectal Neoplasms; DNA Probes; DNA, Neoplasm; Epiderm | 1990 |
Chemosensitivity correlation between the primary tumors and simultaneous metastatic lymph nodes of patients evaluated by DNA synthesis inhibition assay.
Topics: Breast Neoplasms; Carbazilquinone; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Doxorubicin; Drug | 1990 |
In vitro activity of 4'-iodo-4'-deoxydoxorubicin on human colo-rectal cancer as measured by a short-term antimetabolic assay.
Topics: Colorectal Neoplasms; Doxorubicin; Humans; Thymidine; Tumor Cells, Cultured; Uridine | 1990 |
[Clinical value of thymidine kinase activities in sera and tumor tissues of patients with colorectal cancer].
Topics: Biomarkers, Tumor; Colorectal Neoplasms; Humans; Idoxuridine; Iodine Radioisotopes; Neoplasm Staging | 1988 |