Page last updated: 2024-11-06

thymidine and Cirrhosis

thymidine has been researched along with Cirrhosis in 17 studies

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the estimated glomerular filtration rate (eGFR) during telbivudine (LdT) versus entecavir (ETV) treatment in chronic hepatitis B (CHB) patients with underlying comorbidities such as diabetes mellitus (DM), hypertension, and cirrhosis."7.81Comparison of the Effects of Telbivudine and Entecavir Treatment on Estimated Glomerular Filtration Rate in Patients with Chronic Hepatitis B. ( Ahn, SH; Han, KH; Kim, BK; Kim, DY; Kim, SU; Ku, HJ; Lee, S; Park, JY; Song, K, 2015)
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis."7.67Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989)
"Telbivudine (LdT) is an anti-hepatitis B virus (HBV) drug that has been found to steadily improve renal function, but the mechanism of drug action is unclear."5.48Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling. ( Chen, J; Li, D, 2018)
"The aim of this study was to evaluate the estimated glomerular filtration rate (eGFR) during telbivudine (LdT) versus entecavir (ETV) treatment in chronic hepatitis B (CHB) patients with underlying comorbidities such as diabetes mellitus (DM), hypertension, and cirrhosis."3.81Comparison of the Effects of Telbivudine and Entecavir Treatment on Estimated Glomerular Filtration Rate in Patients with Chronic Hepatitis B. ( Ahn, SH; Han, KH; Kim, BK; Kim, DY; Kim, SU; Ku, HJ; Lee, S; Park, JY; Song, K, 2015)
"Telbivudine (beta-l-2'-deoxythymidine) is an orally administered nucleoside analog drug approved for the treatment of patients with chronic hepatitis B since 2006."3.77Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis. ( Dang, S; Gao, N; Jia, X; Zhang, X, 2011)
"7%), fibrosis was significantly reduced in the pentoxifylline- and ciprofloxacin-treated groups (4."3.70Effect of preoperative interventions on outcome following liver resection in a rat model of cirrhosis. ( Gong, Y; Johnson, J; Kneteman, N; Minuk, GY; Moser, M; Zhang, M, 2000)
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis."3.67Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989)
"Telbivudine (LdT) is an anti-hepatitis B virus (HBV) drug that has been found to steadily improve renal function, but the mechanism of drug action is unclear."1.48Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling. ( Chen, J; Li, D, 2018)
"Cirrhosis was induced in mice and normal and cirrhotic hepatocytes were isolated by collagenase perfusion and treated with or without TGFbeta (5 ng/ml)."1.32Cirrhotic hepatocytes exhibit decreased TGFbeta growth inhibition associated with downregulated Smad protein expression. ( Behrns, KE; Bird, MA; Hayden, MA; Lange, PA; Samson, CM, 2004)
"Patients with uremia have excess levels of parathyroid hormone (PTH)."1.28Effect of excess parathyroid hormone on human bone marrow fibroblasts. ( Blum, M; Meytes, D; Ramot, B; Shacked, N, 1990)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's5 (29.41)18.2507
2000's4 (23.53)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, J1
Li, D1
Calvaruso, V1
Craxì, A1
Lee, S1
Park, JY1
Song, K1
Kim, DY1
Kim, BK1
Kim, SU1
Ku, HJ1
Han, KH1
Ahn, SH1
Ikeda, K1
Tojo, K1
Udagawa, T1
Otsubo, C1
Ishikawa, M1
Tokudome, G1
Hosoya, T1
Tajima, N1
Nakao, K1
Kawamura, M1
Dang, S1
Gao, N1
Zhang, X1
Jia, X1
Ahmedat, AS1
Warnken, M1
Seemann, WK1
Mohr, K1
Kostenis, E1
Juergens, UR1
Racké, K1
Lange, PA1
Samson, CM1
Bird, MA1
Hayden, MA1
Behrns, KE1
Ruehl, M1
Erben, U1
Schuppan, D1
Wagner, C1
Zeller, A1
Freise, C1
Al-Hasani, H1
Loesekann, M1
Notter, M1
Wittig, BM1
Zeitz, M1
Dieterich, W1
Somasundaram, R1
Sakanashi, Y1
Takeya, M1
Yoshimura, T1
Feng, L1
Morioka, T1
Takahashi, K1
Franzén, P1
Ichijo, H1
Miyazono, K1
Prakash, S1
Robbins, PW1
Wyler, DJ1
Perfumo, F1
Altieri, P1
Degl'Innocenti, ML1
Ghiggeri, GM1
Caridi, G1
Trivelli, A1
Gusmano, R1
Moser, M1
Zhang, M1
Gong, Y1
Johnson, J1
Kneteman, N1
Minuk, GY1
Meytes, D1
Shacked, N1
Blum, M1
Ramot, B1
Benjamin, IJ1
Jalil, JE1
Tan, LB1
Cho, K1
Weber, KT1
Clark, WA1
Piérard-Franchimont, C1
Damseaux, M1
Mélotte, P1
Piérard, GE1
Barsky, SH1
Gopalakrishna, R1

Reviews

1 review available for thymidine and Cirrhosis

ArticleYear
Regression of fibrosis after HBV antiviral therapy. Is cirrhosis reversible?
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34 Suppl 1

    Topics: Adenine; Administration, Oral; Antiviral Agents; Carcinoma, Hepatocellular; Fibrosis; Guanine; Hepat

2014

Other Studies

16 other studies available for thymidine and Cirrhosis

ArticleYear
Telbivudine attenuates UUO-induced renal fibrosis via TGF-β/Smad and NF-κB signaling.
    International immunopharmacology, 2018, Volume: 55

    Topics: Animals; Antiviral Agents; Disease Models, Animal; Fibrosis; Hepatitis B virus; Humans; Inflammation

2018
Comparison of the Effects of Telbivudine and Entecavir Treatment on Estimated Glomerular Filtration Rate in Patients with Chronic Hepatitis B.
    Gut and liver, 2015, 11-23, Volume: 9, Issue:6

    Topics: Adult; Antiviral Agents; Diabetes Complications; Diabetes Mellitus; Drug Administration Schedule; Fe

2015
Cellular physiology of rat cardiac myocytes in cardiac fibrosis: in vitro simulation using the cardiac myocyte/cardiac non-myocyte co-culture system.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly;

2008
Rhabdomyolysis in a 48-year-old man with hepatitis B-induced cirrhosis.
    The American journal of the medical sciences, 2011, Volume: 342, Issue:1

    Topics: Acute Kidney Injury; Antiviral Agents; Fatal Outcome; Fibrosis; Hepatitis B; Humans; Male; Middle Ag

2011
Pro-fibrotic processes in human lung fibroblasts are driven by an autocrine/paracrine endothelinergic system.
    British journal of pharmacology, 2013, Volume: 168, Issue:2

    Topics: Cell Line; Cells, Cultured; Collagen; Endothelin Receptor Antagonists; Endothelins; Fibroblasts; Fib

2013
Cirrhotic hepatocytes exhibit decreased TGFbeta growth inhibition associated with downregulated Smad protein expression.
    Biochemical and biophysical research communications, 2004, Jan-16, Volume: 313, Issue:3

    Topics: Active Transport, Cell Nucleus; Animals; Blotting, Western; Cell Division; Cell Transformation, Neop

2004
The elongated first fibronectin type III domain of collagen XIV is an inducer of quiescence and differentiation in fibroblasts and preadipocytes.
    The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Apoptosis; Azo Compounds; Biological Transport; Blotting, Western

2005
Kinetics of macrophage subpopulations and expression of monocyte chemoattractant protein-1 (MCP-1) in bleomycin-induced lung injury of rats studied by a novel monoclonal antibody against rat MCP-1.
    Journal of leukocyte biology, 1994, Volume: 56, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Base Sequence; Bleomycin; Blotting, Northern; Cell

1994
Different signals mediate transforming growth factor-beta 1-induced growth inhibition and extracellular matrix production in prostatic carcinoma cells.
    Experimental cell research, 1993, Volume: 207, Issue:1

    Topics: Cell Division; Clone Cells; Drug Resistance; Fibronectins; Fibrosis; Genes, jun; Humans; Male; Plasm

1993
Cloning and analysis of murine cDNA that encodes a fibrogenic lymphokine, fibrosin.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Mar-14, Volume: 92, Issue:6

    Topics: Amino Acid Sequence; Animals; Antibodies; Base Sequence; CD4-Positive T-Lymphocytes; Cell Division;

1995
Effects of peritoneal effluents on mesothelial cells in culture: cell proliferation and extracellular matrix regulation.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:9

    Topics: Adolescent; Ascitic Fluid; Cell Division; Cells, Cultured; Child; Collagen; Epithelium; Extracellula

1996
Effect of preoperative interventions on outcome following liver resection in a rat model of cirrhosis.
    Journal of hepatology, 2000, Volume: 32, Issue:2

    Topics: Animals; Anti-Infective Agents; Aspartate Aminotransferases; Bilirubin; Ciprofloxacin; Diagnosis, Co

2000
Effect of excess parathyroid hormone on human bone marrow fibroblasts.
    Nephron, 1990, Volume: 55, Issue:1

    Topics: Bone Marrow; Bone Marrow Cells; Cell Division; Fibroblasts; Fibrosis; Humans; In Vitro Techniques; P

1990
Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.
    Circulation research, 1989, Volume: 65, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Cardiomegaly; DNA; DNA Replication; Fibrosis; Hear

1989
The fate of hypodermis after liposuction surgery.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:4

    Topics: Adipose Tissue; Adult; Autoradiography; Epidermis; Female; Fibrosis; Humans; Lipectomy; Necrosis; Sk

1988
An experimental model for studying the desmoplastic response to tumor invasion.
    Cancer letters, 1987, Volume: 35, Issue:3

    Topics: Animals; Cell Line; Collagen; Female; Fibrosis; Hydroxyproline; Melanoma; Mice; Mice, Inbred C57BL;

1987