thymidine has been researched along with Chromosome Deletion in 11 studies
Chromosome Deletion: Actual loss of portion of a chromosome.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A model established on the gene dosage effect, which likely results of these chromosome imbalances, may be proposed: (1) increase of thymidine kinase activity (chromosome 17q) and thus of the salvage pathway of thymidine synthesis (2) decrease of thymidine de novo pathways by decreased of thymidylate synthase (chromosome 18) and of dihydrofolate reductase (chromosome 5q) and thus accumulation of 2'-deoxyuridine-5'-P, which saves 2'-deoxycytidine 5'-P (3) decrease of cytidylate (or uridylate) kinase (chromosome 1p) and thus accumulation of 2-deoxycytidine-5-PP and of uridine-5-P (UMP) decreasing the metabolisation of orotidine-5'-P, precursor of 2-deoxycytidine-5-PP, which (4) saves -D-5-ribosyl-PP (PRPP) or even conversion of orotidine-5'-P in PRPP." | 2.37 | Induction of increased salvage pathways of nucleotide synthesis by dosage effect due to chromosome imbalances may be fundamental in carcinogenesis: the example of colorectal carcinoma. ( Dutrillaux, B; Muleris, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (63.64) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Olivieri, G | 1 |
| Bodycote, J | 1 |
| Wolff, S | 1 |
| Daikoku, T | 1 |
| Yamamoto, N | 1 |
| Maeno, K | 1 |
| Nishiyama, Y | 1 |
| Flanagan, JG | 1 |
| Chan, DC | 1 |
| Leder, P | 1 |
| Cortés, F | 1 |
| Domínguez, I | 1 |
| Mateos, S | 1 |
| Piñero, J | 1 |
| Mateos, JC | 1 |
| Stein, RW | 1 |
| Corrigan, M | 1 |
| Yaciuk, P | 1 |
| Whelan, J | 1 |
| Moran, E | 1 |
| Dutrillaux, B | 1 |
| Muleris, M | 1 |
| Preston, VG | 1 |
| Darling, AJ | 1 |
| McDougall, IM | 1 |
| Quinlan, MP | 1 |
| Whyte, P | 1 |
| Grodzicker, T | 1 |
| Livneh, E | 1 |
| Prywes, R | 1 |
| Kashles, O | 1 |
| Reiss, N | 1 |
| Sasson, I | 1 |
| Mory, Y | 1 |
| Ullrich, A | 1 |
| Schlessinger, J | 1 |
| Shelley, CS | 1 |
| Baralle, FE | 1 |
| Goldsmith, ME | 1 |
| Cowan, KH | 1 |
1 review available for thymidine and Chromosome Deletion
| Article | Year |
|---|---|
Induction of increased salvage pathways of nucleotide synthesis by dosage effect due to chromosome imbalances may be fundamental in carcinogenesis: the example of colorectal carcinoma.
Topics: Chromosome Aberrations; Chromosome Deletion; Chromosomes, Human, 1-3; Chromosomes, Human, 16-18; Chr | 1986 |
10 other studies available for thymidine and Chromosome Deletion
| Article | Year |
|---|---|
Adaptive response of human lymphocytes to low concentrations of radioactive thymidine.
Topics: Cells, Cultured; Chromosome Aberrations; Chromosome Deletion; Humans; Lymphocytes; Metaphase; Thymid | 1984 |
Role of viral ribonucleotide reductase in the increase of dTTP pool size in herpes simplex virus-infected Vero cells.
Topics: Animals; Chromosome Deletion; Floxuridine; Hydroxyurea; Kinetics; Phosphorylation; Ribonucleotide Re | 1991 |
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Adhesion; Cell Line; Cells, Cultured; Chromosome D | 1991 |
Evidence for an adaptive response to radiation damage in plant cells conditioned with X-rays or incorporated tritium.
Topics: Adaptation, Biological; Chromatids; Chromosome Aberrations; Chromosome Deletion; DNA; Plant Cells; P | 1990 |
Analysis of E1A-mediated growth regulation functions: binding of the 300-kilodalton cellular product correlates with E1A enhancer repression function and DNA synthesis-inducing activity.
Topics: Adenovirus Early Proteins; Adenoviruses, Human; Animals; Antibodies, Monoclonal; Cell Line; Cell Tra | 1990 |
The herpes simplex virus type 1 temperature-sensitive mutant ts1222 has a single base pair deletion in the small subunit of ribonucleotide reductase.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Deletion; Culture Media; DNA, Viral; Genes, Viral; Hy | 1988 |
Growth factor induction by the adenovirus type 5 E1A 12S protein is required for immortalization of primary epithelial cells.
Topics: Adenovirus Early Proteins; Adenoviruses, Human; Animals; Antigens, Viral, Tumor; Cell Line; Cell Tra | 1988 |
Reconstitution of human epidermal growth factor receptors and its deletion mutants in cultured hamster cells.
Topics: Animals; Cells, Cultured; Chromosome Deletion; Cricetinae; DNA; DNA Replication; Epidermal Growth Fa | 1986 |
Deletion analysis of a unique 3' splice site indicates that alternating guanine and thymine residues represent an efficient splicing signal.
Topics: Apolipoprotein A-II; Apolipoproteins A; Base Sequence; Chromosome Deletion; Guanine; Humans; Introns | 1987 |
Modulation of a human dihydrofolate reductase minigene following release from amino acid deprivation involves both 5' and 3' nucleotide sequences.
Topics: Amino Acids; Animals; Chromosome Deletion; Cricetinae; Cricetulus; DNA; DNA Replication; RNA, Messen | 1988 |