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thymidine and Choriocarcinoma

thymidine has been researched along with Choriocarcinoma in 16 studies

Choriocarcinoma: A malignant metastatic form of trophoblastic tumors. Unlike the HYDATIDIFORM MOLE, choriocarcinoma contains no CHORIONIC VILLI but rather sheets of undifferentiated cytotrophoblasts and syncytiotrophoblasts (TROPHOBLASTS). It is characterized by the large amounts of CHORIONIC GONADOTROPIN produced. Tissue origins can be determined by DNA analyses: placental (fetal) origin or non-placental origin (CHORIOCARCINOMA, NON-GESTATIONAL).

Research Excerpts

ExcerptRelevanceReference
"We have examined binding of [3H]nitrobenzylthioinosine (NBMPR) and influx of [3H]thymidine in adherent cultures of human choriocarcinoma (BeWo) cells and, for comparison, cervical-carcinoma (HeLa) cells."7.68Expression of high levels of nitrobenzylthioinosine-sensitive nucleoside transport in cultured human choriocarcinoma (BeWo) cells. ( Boumah, CE; Cass, CE; Hogue, DL, 1992)
"During exposure to methotrexate, cultured human choriocarcinoma (BeWo) cells stop proliferating, enlarge, and undergo a complex differentiative response that resembles in utero development of quiescent syncytiotrophoblasts."7.67Inhibition of methotrexate-induced differentiation of cultured human choriocarcinoma (BeWo) cells by thymidine. ( Burres, NS; Cass, CE, 1987)
"A new anticancer drug, VP16-213 was studied in vitro to determine its effect upon 3H-thymidine uptake and the survival rate of choriocarcinoma cells in comparison with the effect of MTX and Act-D."7.67[Anticancer effect of VP16-213 (etoposide) on three choriocarcinoma cell lines]. ( Kobayashi, O; Matsui, H; Sekiya, S; Shirotake, S; Takamizawa, H, 1987)
"A human choriocarcinoma cell line, HCCM-5, was fed with medium containing increasing concentrations of methotrexate (MTX)."7.67Development of methotrexate-resistant human choriocarcinoma cells in culture. ( Kaiho, T; Sekiya, S; Takamizawa, H, 1985)
"Treatment of the BeWo line of choriocarcinoma cells with methotrexate in doses that inhibit DNA synthesis causes a tenfold increase in synthesis of human chorionic gonadotropin and a threefold increase in activity of placental alkaline phosphatase."7.65The stimulation by methotrexate of human chorionic gonadotropin and placental alkaline phosphatase in cultured choriocarcinoma cells. ( Azizkhan, JC; Speeg, KV; Stromberg, K, 1976)
"We have examined binding of [3H]nitrobenzylthioinosine (NBMPR) and influx of [3H]thymidine in adherent cultures of human choriocarcinoma (BeWo) cells and, for comparison, cervical-carcinoma (HeLa) cells."3.68Expression of high levels of nitrobenzylthioinosine-sensitive nucleoside transport in cultured human choriocarcinoma (BeWo) cells. ( Boumah, CE; Cass, CE; Hogue, DL, 1992)
"During exposure to methotrexate, cultured human choriocarcinoma (BeWo) cells stop proliferating, enlarge, and undergo a complex differentiative response that resembles in utero development of quiescent syncytiotrophoblasts."3.67Inhibition of methotrexate-induced differentiation of cultured human choriocarcinoma (BeWo) cells by thymidine. ( Burres, NS; Cass, CE, 1987)
"A new anticancer drug, VP16-213 was studied in vitro to determine its effect upon 3H-thymidine uptake and the survival rate of choriocarcinoma cells in comparison with the effect of MTX and Act-D."3.67[Anticancer effect of VP16-213 (etoposide) on three choriocarcinoma cell lines]. ( Kobayashi, O; Matsui, H; Sekiya, S; Shirotake, S; Takamizawa, H, 1987)
"A human choriocarcinoma cell line, HCCM-5, was fed with medium containing increasing concentrations of methotrexate (MTX)."3.67Development of methotrexate-resistant human choriocarcinoma cells in culture. ( Kaiho, T; Sekiya, S; Takamizawa, H, 1985)
"Treatment of the BeWo line of choriocarcinoma cells with methotrexate in doses that inhibit DNA synthesis causes a tenfold increase in synthesis of human chorionic gonadotropin and a threefold increase in activity of placental alkaline phosphatase."3.65The stimulation by methotrexate of human chorionic gonadotropin and placental alkaline phosphatase in cultured choriocarcinoma cells. ( Azizkhan, JC; Speeg, KV; Stromberg, K, 1976)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's3 (18.75)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakanishi, T1
Hiromori, Y1
Yokoyama, H1
Koyanagi, M1
Itoh, N1
Nishikawa, J1
Tanaka, K1
Sooranna, SR1
Patel, S1
Das, I1
Speeg, KV1
Azizkhan, JC1
Stromberg, K1
Hohn, HP1
Parker, CR1
Boots, LR1
Denker, HW1
Höök, M1
Boumah, CE1
Hogue, DL1
Cass, CE2
Burres, NS1
Matsui, H1
Kobayashi, O1
Shirotake, S1
Sekiya, S3
Takamizawa, H3
Kuwata, T1
Ishige, H1
Tomita, Y1
Kaiho, T1
Takeuchi, S1
Kanazawa, K1
Maráz, A1
Petri, IB1
Hussa, RO3
Pattillo, RA3
Kozinets, GI1
Bogoiavlenskaia, MP1
Al'perovich, VV1
Bykova, IA1
Orlov, GP1
Delfs, FE1
Mattingly, RF2
Oama, K1
Garancis, JC1
Ruckert, AC1

Other Studies

16 other studies available for thymidine and Choriocarcinoma

ArticleYear
Organotin compounds enhance 17beta-hydroxysteroid dehydrogenase type I activity in human choriocarcinoma JAr cells: potential promotion of 17beta-estradiol biosynthesis in human placenta.
    Biochemical pharmacology, 2006, Apr-28, Volume: 71, Issue:9

    Topics: 17-Hydroxysteroid Dehydrogenases; Cell Line, Tumor; Choriocarcinoma; Estradiol; Gene Expression Regu

2006
The effect of garlic on cell growth and cell division in cultured trophoblast and endothelial cell lines.
    Biochemical Society transactions, 1997, Volume: 25, Issue:3

    Topics: Allyl Compounds; Antineoplastic Agents; Cell Division; Cells, Cultured; Choriocarcinoma; Endothelium

1997
The stimulation by methotrexate of human chorionic gonadotropin and placental alkaline phosphatase in cultured choriocarcinoma cells.
    Cancer research, 1976, Volume: 36, Issue:12

    Topics: Alkaline Phosphatase; Cells, Cultured; Choriocarcinoma; Chorionic Gonadotropin; DNA, Neoplasm; Dose-

1976
Modulation of differentiation markers in human choriocarcinoma cells by extracellular matrix: on the role of a three-dimensional matrix structure.
    Differentiation; research in biological diversity, 1992, Volume: 51, Issue:1

    Topics: Alkaline Phosphatase; Cell Adhesion; Cell Differentiation; Cell Division; Choriocarcinoma; Chorionic

1992
Expression of high levels of nitrobenzylthioinosine-sensitive nucleoside transport in cultured human choriocarcinoma (BeWo) cells.
    The Biochemical journal, 1992, Dec-15, Volume: 288 ( Pt 3)

    Topics: Binding Sites; Biological Transport; Carrier Proteins; Cell Membrane; Choriocarcinoma; Electrophores

1992
Inhibition of methotrexate-induced differentiation of cultured human choriocarcinoma (BeWo) cells by thymidine.
    Cancer research, 1987, Oct-01, Volume: 47, Issue:19

    Topics: Cell Differentiation; Cells, Cultured; Choriocarcinoma; DNA; DNA Replication; Female; Humans; Hypoxa

1987
[Anticancer effect of VP16-213 (etoposide) on three choriocarcinoma cell lines].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:6

    Topics: Cell Line; Choriocarcinoma; DNA, Neoplasm; Drug Evaluation, Preclinical; Etoposide; Female; Humans;

1987
Effects of human interferons on human choriocarcinoma cells in vitro and in vivo.
    Gynecologic oncology, 1986, Volume: 25, Issue:1

    Topics: Animals; Cell Line; Cell Survival; Choriocarcinoma; Chorionic Gonadotropin; Cricetinae; Female; Huma

1986
Development of methotrexate-resistant human choriocarcinoma cells in culture.
    Gynecologic oncology, 1985, Volume: 21, Issue:1

    Topics: Biological Transport; Cell Division; Cell Line; Cells, Cultured; Choriocarcinoma; Chorionic Gonadotr

1985
Changes of immunologic competence of lymphocytes evaluated by phytohemagglutinin (PHA)-induced DNA synthesis related to pregnancy and gynecologic tumors.
    Acta obstetrica et gynaecologica Japonica, 1972, Volume: 19, Issue:1

    Topics: Choriocarcinoma; DNA; DNA, Neoplasm; Female; Humans; Hydatidiform Mole; Hyperemesis Gravidarum; Lect

1972
Intrinsic alteration of lymphocyte reactivity in women with normal pregnancy or tumor of placental origin.
    Cellular immunology, 1974, Mar-15, Volume: 10, Issue:3

    Topics: Adult; Cell-Free System; Cells, Cultured; Choriocarcinoma; Deoxyribonucleases; DNA; Female; Hot Temp

1974
Effects of methotrexate on established cell lines of human choriocarcinoma.
    European journal of cancer, 1972, Volume: 8, Issue:5

    Topics: Cell Line; Choriocarcinoma; Deoxyuridine; Depression, Chemical; DNA, Neoplasm; Female; Folic Acid An

1972
[Change in peripheral blood lymphocytes with radiotherapy].
    Meditsinskaia radiologiia, 1972, Volume: 17, Issue:11

    Topics: Adult; Breast Neoplasms; Choriocarcinoma; Female; Humans; Lectins; Leukocytes; Lymphocyte Activation

1972
Actinomycin D stimulation of HCG production by human choriocarcinoma.
    Obstetrics and gynecology, 1973, Volume: 42, Issue:5

    Topics: Animals; Carbon Radioisotopes; Cattle; Cell Line; Cells, Cultured; Choriocarcinoma; Chorionic Gonado

1973
[Cyto-immunological study in the field of obstetrics using mixed leukocyte culture].
    Nihon Sanka Fujinka Gakkai zasshi, 1971, Volume: 23, Issue:6

    Topics: Abortion, Habitual; Blood Group Antigens; Choriocarcinoma; Culture Techniques; Female; Genital Disea

1971
A malignant trophoblastic cell line: high rates of DNA synthesis measured by a rapid disc method.
    Journal of the National Cancer Institute, 1970, Volume: 45, Issue:6

    Topics: Animals; Cell Count; Choriocarcinoma; Culture Techniques; Dactinomycin; DNA, Neoplasm; Female; Filtr

1970