thymidine has been researched along with Choreoathetosis Self-Mutilation Hyperuricemia Syndrome in 13 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "The inherited disease Lesch-Nyhan syndrome, which is caused by a deficiency of the enzyme hypoxanthine phosphoribosyltransferase (HPRT), is characterized by behavioural alterations, including self-injurious behaviour and mental retardation." | 7.68 | Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice. ( Melton, DW; Wu, CL, 1993) |
| "The inherited disease Lesch-Nyhan syndrome, which is caused by a deficiency of the enzyme hypoxanthine phosphoribosyltransferase (HPRT), is characterized by behavioural alterations, including self-injurious behaviour and mental retardation." | 3.68 | Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice. ( Melton, DW; Wu, CL, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (84.62) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Strauss, GH | 1 |
| Allen, EF | 1 |
| Albertini, RJ | 2 |
| Wu, CL | 1 |
| Melton, DW | 1 |
| Cheng, RZ | 1 |
| Shammas, MA | 1 |
| Li, J | 1 |
| Shmookler Reis, RJ | 1 |
| Allison, AC | 2 |
| Hovi, T | 2 |
| Watts, RW | 2 |
| Webster, AD | 2 |
| de Bruyn, C | 1 |
| Gausset, P | 1 |
| Duchateau, J | 1 |
| Vamos, E | 1 |
| Kulakowski, S | 1 |
| Delespesse, G | 1 |
| Zielke, HR | 1 |
| Ozand, PT | 1 |
| Tildon, JT | 1 |
| Sevdalian, DA | 1 |
| Cornblath, M | 1 |
| Bakay, B | 1 |
| Nyhan, WL | 1 |
| Croce, CM | 1 |
| Koprowski, H | 1 |
| Jenkins, EC | 1 |
| DeMars, R | 1 |
| van Zeeland, AA | 1 |
| de Ruijter, CE | 1 |
| Simons, JW | 1 |
| Wood, S | 1 |
| Pinsky, L | 1 |
| Siniscalco, M | 1 |
| Knowles, BB | 1 |
| Steplewski, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase 1 Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors[NCT00923728] | 0 participants (Actual) | Interventional | 2009-04-30 | Withdrawn | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thymidine and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
The role of de novo purine synthesis in lymphocyte transformation.
Topics: Adenine Phosphoribosyltransferase; Adenosine Deaminase; Adolescent; Adult; Allopurinol; Azaserine; B | 1977 |
12 other studies available for thymidine and Choreoathetosis Self-Mutilation Hyperuricemia Syndrome
| Article | Year |
|---|---|
An enumerative assay of purine analogue resistant lymphocytes in women heterozygous for the Lesch-Nyhan Mutation.
Topics: Adolescent; Adult; Aged; Autoradiography; Child; Drug Resistance; Female; Fibroblasts; Genetic Carri | 1980 |
Production of a model for Lesch-Nyhan syndrome in hypoxanthine phosphoribosyltransferase-deficient mice.
Topics: Adenine; Adenine Phosphoribosyltransferase; Animals; Brain; Caffeine; Cell Division; Cells, Cultured | 1993 |
Expression of SV40 large T antigen stimulates reversion of a chromosomal gene duplication in human cells.
Topics: Antigens, Polyomavirus Transforming; Cell Division; Cell Line, Transformed; Cell Transformation, Vir | 1997 |
Immunological observations on patients with Lesch-Nyhan syndrome, and on the role of de-novo purine synthesis in lymphocyte transformation.
Topics: Adenosine Deaminase; Adolescent; Azaserine; B-Lymphocytes; Child; Child, Preschool; Hemagglutinins; | 1975 |
Immunological studies on Lesch-Nyhan patients.
Topics: Adolescent; Child; DNA Replication; Erythrocytes; Humans; Immunoglobulins; Lesch-Nyhan Syndrome; Lym | 1979 |
Growth of human diploid fibroblasts in the absence of glucose utilization.
Topics: Cell Division; Cells, Cultured; Culture Media; Glucose; Glutamates; Glutamine; Humans; Hypoxanthines | 1976 |
Reversion in expression of hypoxanthine-guanine phosphoribosyl transferase following cell hybridization.
Topics: Aminopterin; Animals; Cell Fusion; Cell Line; Clone Cells; Cricetinae; Culture Media; Electrophoresi | 1975 |
Wire-loop application of liquid emulsion to slides for autoradiography in light microscopy.
Topics: Autoradiography; Chromosomes, Human, 13-15; Detergents; Emulsions; Histological Techniques; Humans; | 1972 |
Mosaicism of peripheral blood lymphocyte populations in females heterozygous for the Lesch-Nyhan mutation.
Topics: Adolescent; Adult; Azaguanine; Evaluation Studies as Topic; Female; Gene Frequency; Hemagglutination | 1974 |
The role of 8-azaguanine in the selection from human diploid cells of mutants deficient in hypoxanthine-guanine-phosphoribosyl-transferase (HGPRT).
Topics: Aminopterin; Autoradiography; Azaguanine; Cell Line; Clone Cells; Culture Media; Drug Resistance; Fi | 1974 |
Adaptive significance of inosine and adenosine kinase activities in cultured human skin fibroblasts.
Topics: Adenine; Adenosine; Azaserine; Cells, Cultured; Fibroblasts; Guanine; Humans; Hypoxanthines; Inosine | 1972 |
Hybridization of human diploid strains carrying X-linked mutants and its potential in studies of somatic cell genetics.
Topics: Anemia, Hemolytic, Congenital Nonspherocytic; Autoradiography; Cell Fusion; Cell Line; Cell Nucleus; | 1969 |