Page last updated: 2024-11-06

thymidine and Cholera Infantum

thymidine has been researched along with Cholera Infantum in 14 studies

Research Excerpts

ExcerptRelevanceReference
"Two sisters, initially managed for Crohn's disease based upon clinical, imaging and pathological findings, were later found to have MNGIE."1.51Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn's disease. ( Chinnery, PF; Coulter, LL; Parkes, M; Patel, R; Rimmer, J; Swift, O, 2019)
"Seven patients with gastrointestinal disorders and deficiencies of serum and secretory immunoglobulins were evaluated clinically, microbiologically, and immunologically."1.25Clinical, microbiological, and immunological studies in patients with immunoglobulin deficiencies and gastrointestinal disorders. ( Brown, WR; Butterfield, D; Savage, D; Tada, T, 1972)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's0 (0.00)18.2507
2000's9 (64.29)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Patel, R1
Coulter, LL1
Rimmer, J1
Parkes, M1
Chinnery, PF1
Swift, O1
Moran, NF2
Bain, MD1
Muqit, MM1
Bax, BE2
Miralles Alvarez, C1
Borhani Haghighi, A1
Nabavizadeh, A1
Sass, JO1
Safari, A1
Lankarani, KB1
Baine, M1
Song, S1
Wheeler, LJ1
Mathews, CK1
Martí, R3
Spinazzola, A1
Tadesse, S2
Nishino, I1
Nishigaki, Y1
Hirano, M4
Pontarin, G1
Ferraro, P1
Valentino, ML3
Reichard, P1
Bianchi, V1
Lara, MC1
Weiss, B1
Illa, I1
Madoz, P1
Massuet, L1
Andreu, AL1
Anikster, Y1
Yavuz, H1
Ozel, A1
Christensen, M1
Christensen, E1
Schwartz, M1
Elmaci, M1
Vissing, J1
López, LC1
Manes, JL1
Lyzak, J1
Hahn, A1
Carelli, V1
Brown, WR1
Butterfield, D1
Savage, D1
Tada, T1
Lipkin, M1
McDermott, FT1
Nayman, J1
de Boer, WG1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Safety, Tolerability, Pharmacodynamics, and Efficacy of Erythrocyte Encapsulated Thymidine Phosphorylase (EE-TP) in Patients With MNGIE[NCT03866954]Phase 20 participants (Actual)Interventional2024-11-30Withdrawn (stopped due to Change of circumstances with Commercial partner)
A Phase II, Monocenter, Single Arm Study To Assess The Safety and Efficacy Of Combination Deoxycytidine and Deoxythymidine For Mitochondrial Depletion Disorders[NCT04802707]Phase 250 participants (Anticipated)Interventional2021-10-18Recruiting
MNGIE (Mitochondrial Neurogastrointestinal Encephalomyopathy) AHSCT (Allogeneic Hematopoietic Stem Cell Transplant) Safety Study[NCT02427178]Phase 10 participants (Actual)Interventional2015-03-31Withdrawn (stopped due to Poor enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thymidine and Cholera Infantum

ArticleYear
[Are all analogue combinations equal?].
    Enfermedades infecciosas y microbiologia clinica, 2008, Volume: 26 Suppl 8

    Topics: Adenine; Anti-HIV Agents; Antimetabolites; Antiretroviral Therapy, Highly Active; Cardiovascular Dis

2008

Other Studies

13 other studies available for thymidine and Cholera Infantum

ArticleYear
Mitochondrial neurogastrointestinal encephalopathy: a clinicopathological mimic of Crohn's disease.
    BMC gastroenterology, 2019, Jan-15, Volume: 19, Issue:1

    Topics: Adult; Age of Onset; Azathioprine; Crohn Disease; Deoxyuridine; Diagnosis, Differential; Female; Gas

2019
Carrier erythrocyte entrapped thymidine phosphorylase therapy for MNGIE.
    Neurology, 2008, Aug-26, Volume: 71, Issue:9

    Topics: Adult; Deoxyuridine; Drug Delivery Systems; Erythrocyte Transfusion; Erythrocytes; Fatal Outcome; Fe

2008
Mitochondrial neurogastrointestinal encephalomyopathy.
    Archives of Iranian medicine, 2009, Volume: 12, Issue:6

    Topics: Adult; Gastrointestinal Diseases; Humans; Magnetic Resonance Imaging; Male; Mitochondrial Encephalom

2009
Mitochondrial neurogastrointestinal encephalopathy without elevated thymidine levels.
    Archives of neurology, 2010, Volume: 67, Issue:5

    Topics: Biomarkers; Bone Marrow Transplantation; Brain Diseases, Metabolic; Enzyme Replacement Therapy; Gast

2010
Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA.
    The Journal of biological chemistry, 2003, Nov-07, Volume: 278, Issue:45

    Topics: Base Pairing; Blotting, Southern; Deoxyadenine Nucleotides; Deoxycytosine Nucleotides; Deoxyguanine

2003
Definitive diagnosis of mitochondrial neurogastrointestinal encephalomyopathy by biochemical assays.
    Clinical chemistry, 2004, Volume: 50, Issue:1

    Topics: Chromatography, High Pressure Liquid; Deoxyuridine; Gastrointestinal Diseases; Humans; Mitochondrial

2004
Mitochondrial DNA depletion and thymidine phosphate pool dynamics in a cellular model of mitochondrial neurogastrointestinal encephalomyopathy.
    The Journal of biological chemistry, 2006, Aug-11, Volume: 281, Issue:32

    Topics: Adenosine Triphosphate; Cytosol; DNA, Mitochondrial; Fibroblasts; Gastrointestinal Diseases; Humans;

2006
Infusion of platelets transiently reduces nucleoside overload in MNGIE.
    Neurology, 2006, Oct-24, Volume: 67, Issue:8

    Topics: Adolescent; Adult; Deoxyuridine; Female; Gastrointestinal Diseases; Humans; Male; Mitochondrial Ence

2006
Treatment of mitochondrial neurogastrointestinal encephalomyopathy with dialysis.
    Archives of neurology, 2007, Volume: 64, Issue:3

    Topics: Adolescent; Deoxyuridine; Female; Gastrointestinal Diseases; Humans; Longitudinal Studies; Magnetic

2007
Thymidine and deoxyuridine accumulate in tissues of patients with mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
    FEBS letters, 2007, Jul-24, Volume: 581, Issue:18

    Topics: Adolescent; Adult; Autopsy; Biopsy; Deoxyuridine; Female; Gastrointestinal Diseases; Humans; Infant;

2007
Clinical, microbiological, and immunological studies in patients with immunoglobulin deficiencies and gastrointestinal disorders.
    Gut, 1972, Volume: 13, Issue:6

    Topics: Adolescent; Adult; Agammaglobulinemia; Aged; Biopsy; Diarrhea; Female; Fluorescent Antibody Techniqu

1972
Cell proliferation in gastrointestinal disease.
    National Cancer Institute monograph, 1969, Volume: 30

    Topics: Atrophy; Autoradiography; Biopsy; Cell Division; DNA; DNA, Neoplasm; Epithelial Cells; Epithelium; F

1969
Epithelial cell division in acute renal failure: a radio-autographic study in the oesophagus of the mouse.
    The British journal of surgery, 1971, Volume: 58, Issue:1

    Topics: Acute Kidney Injury; Animals; Autoradiography; Cell Division; Epithelium; Esophagus; Gastrointestina

1971