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thymidine and Cardiomegaly

thymidine has been researched along with Cardiomegaly in 23 studies

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis."7.67Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989)
" Endothelin-1 (ET-1), one of the endogenous pathological humoral factors of cardiovascular diseases such as hypertension and heart failure, has a strong vasoconstrictive action and could induce hypertension and cardiac hypertrophy."3.70Possible involvement of endothelin-1 in cardioprotective effects of benidipine. ( Akashi, T; Harada, M; Hosoya, T; Ikeda, K; Nakagawa, O; Nakao, K; Tojo, K; Tokudome, G, 2000)
"Treatment of rats with the beta-adrenergic agonist isoproterenol results in cardiac hypertrophy, myocyte necrosis, and interstitial cell fibrosis."3.67Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis. ( Benjamin, IJ; Cho, K; Clark, WA; Jalil, JE; Tan, LB; Weber, KT, 1989)
"The role of the AT2-receptor in cardiac hypertrophy is controversial, with some reports indicating that AT2-receptor activation has detrimental effects on disease progression, whereas others indicate that it has a beneficial role."1.42Function and expression of ATIP and its variants in cardiomyoblast cell line H9c2. ( Chow, L; Frauman, AG; Krezel, MA; Louis, SN; Louis, WJ; Rezmann, L; Varghayee, N, 2015)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199017 (73.91)18.7374
1990's2 (8.70)18.2507
2000's3 (13.04)29.6817
2010's1 (4.35)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Varghayee, N1
Krezel, MA1
Rezmann, L1
Chow, L1
Frauman, AG1
Louis, WJ1
Louis, SN1
Ikeda, K2
Tojo, K2
Udagawa, T1
Otsubo, C1
Ishikawa, M1
Tokudome, G2
Hosoya, T2
Tajima, N1
Nakao, K2
Kawamura, M1
Hattori, Y1
Akimoto, K1
Nishikimi, T1
Matsuoka, H1
Kasai, K1
MangiarĂșa, E1
Basso, N1
Dubner, D1
Ruiz, P1
Taquini, AC1
Carlier, PG1
Rorive, GL1
Clubb, FJ1
Bishop, SP1
Kunz, J1
Braselmann, H1
Gottschalk, J1
Kreher, C1
Pieper, KS1
Kira, Y1
Nakaoka, T1
Hashimoto, E1
Okabe, F1
Asano, S1
Sekine, I1
Akashi, T1
Harada, M1
Nakagawa, O1
Kranz, D1
Kunde, D1
Fuhrmann, I1
Dowell, RT1
McManus, RE1
Sadoshima, J1
Jahn, L1
Takahashi, T1
Kulik, TJ1
Izumo, S1
Benjamin, IJ1
Jalil, JE1
Tan, LB1
Cho, K1
Weber, KT1
Clark, WA1
Meerson, FZ2
Alekhina, GM2
Aleksandrov, PN1
Bazardjan, AG1
Mirakian, VO1
Rumiantsev, PP1
Grove, D1
Zak, R2
Nair, KG1
Aschenbrenner, V2
Sasaki, R1
Morishita, T1
Ichikawa, S1
Yamagata, S1
Neffgen, JF1
Korecky, B1
Skosey, JL1
Martin, AF1
Rabinowitz, M1
Pomoinitsky, VD1
Mandache, E1
Unge, G1
Appelgren, LE1
Ljungqvist, A1
Steinert, W1
Pfitzer, P1
Friedrich, G1
Stoepel, K1

Other Studies

23 other studies available for thymidine and Cardiomegaly

ArticleYear
Function and expression of ATIP and its variants in cardiomyoblast cell line H9c2.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:1

    Topics: Animals; Cardiomegaly; Cell Line; Cell Proliferation; Cell Size; Genetic Vectors; Intracellular Sign

2015
Cellular physiology of rat cardiac myocytes in cardiac fibrosis: in vitro simulation using the cardiac myocyte/cardiac non-myocyte co-culture system.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:4

    Topics: Angiotensin II; Angiotensinogen; Animals; Animals, Newborn; Atrial Natriuretic Factor; Cardiomegaly;

2008
Activation of AMP-activated protein kinase enhances angiotensin ii-induced proliferation in cardiac fibroblasts.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 47, Issue:2

    Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Angiotensin II; Animals; Cardiomegaly; Ce

2006
Evidence of early structural change in the artery wall of two-kidney one-clip Goldblatt hypertensive rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:8

    Topics: Animals; Blood Pressure; Cardiomegaly; Collagen; Disease Models, Animal; DNA; Elastin; Hyperplasia;

1982
Evolution of aortic hyperplasia after reversal of renovascular hypertension in the rat.
    Archives internationales de physiologie et de biochimie, 1983, Volume: 91, Issue:3

    Topics: Animals; Aorta; Cardiomegaly; DNA; Female; Hyperplasia; Hypertension, Renovascular; Muscle, Smooth,

1983
Formation of binucleated myocardial cells in the neonatal rat. An index for growth hypertrophy.
    Laboratory investigation; a journal of technical methods and pathology, 1984, Volume: 50, Issue:5

    Topics: Animals; Animals, Newborn; Autoradiography; Cardiomegaly; DNA; Growth; Myocardium; Rats; Rats, Inbre

1984
The myocardial collagenous connective tissue in experimental cardiac hypertrophy induced by swimming exercise and hypertension.
    Experimental pathology, 1981, Volume: 19, Issue:4

    Topics: Animals; Autoradiography; Cardiomegaly; Collagen; Connective Tissue; Hydroxyproline; Hypertension; M

1981
Effect of long-term cyclic mechanical load on protein synthesis and morphological changes in cultured myocardial cells from neonatal rat.
    Cardiovascular drugs and therapy, 1994, Volume: 8, Issue:2

    Topics: Animals; Animals, Newborn; Carbon Radioisotopes; Cardiomegaly; Cell Size; Cells, Cultured; Disease M

1994
Possible involvement of endothelin-1 in cardioprotective effects of benidipine.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:5

    Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Cardiomegaly; Cells, Cultured; Dihydropyridines

2000
[The adaption growth of the heart in the higher (experimental autoradiographic researches in rats) (author's transl)].
    Zeitschrift fur Alternsforschung, 1976, Volume: 31, Issue:2

    Topics: Aging; Animals; Aortic Valve Stenosis; Autoradiography; Body Weight; Cardiomegaly; Male; Mitotic Ind

1976
Pressure-induced cardiac enlargement in neonatal and adult rats. Left ventricular functional characteristics and evidence of cardiac muscle cell proliferation in the neonate.
    Circulation research, 1978, Volume: 42, Issue:3

    Topics: Aging; Animals; Animals, Newborn; Body Weight; Cardiomegaly; Cell Division; Male; Myocardial Contrac

1978
Molecular characterization of the stretch-induced adaptation of cultured cardiac cells. An in vitro model of load-induced cardiac hypertrophy.
    The Journal of biological chemistry, 1992, May-25, Volume: 267, Issue:15

    Topics: Adaptation, Physiological; Blood; Blotting, Northern; Cardiomegaly; Cells, Cultured; Creatine Kinase

1992
Isoproterenol-induced myocardial fibrosis in relation to myocyte necrosis.
    Circulation research, 1989, Volume: 65, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Autoradiography; Cardiomegaly; DNA; DNA Replication; Fibrosis; Hear

1989
Dynamics of nucleic acid and protein synthesis of the myocardium in compensatory hyperfunction and hypertrophy of the heart.
    The American journal of cardiology, 1968, Volume: 22, Issue:3

    Topics: Animals; Aortic Coarctation; Aortic Valve Stenosis; Cardiomegaly; Castration; Cell Nucleus; Connecti

1968
[DNA synthesis in postnatal histogenesis of the myocardium and in myocardial infarction, hypertrophy and regeneration (cytophotometric and radioautographic studies)].
    Tsitologiia, 1968, Volume: 10, Issue:8

    Topics: Animals; Anura; Autoradiography; Cardiomegaly; DNA; Heart; Male; Mitosis; Myocardial Infarction; Myo

1968
[On the possible role of the interorgan transport of nucleic acids in the development of compensatory heart hypertrophy].
    Kardiologiia, 1967, Volume: 7, Issue:11

    Topics: Animals; Aortic Coarctation; Autoradiography; Biological Transport; Cardiomegaly; Cell Nucleus; DNA;

1967
Biochemical correlates of cardiac hypertrophy. IV. Observations on the cellular organization of growth during myocardial hypertrophy in the rat.
    Circulation research, 1969, Volume: 25, Issue:4

    Topics: Animals; Aorta; Autoradiography; Cardiomegaly; Cell Nucleus; Connective Tissue; Connective Tissue Ce

1969
Autoradiographic studies and mitosis of heart muscle cells in experimental cardiac hypertrophy.
    The Tohoku journal of experimental medicine, 1970, Volume: 102, Issue:2

    Topics: Animals; Autoradiography; Cardiomegaly; Colchicine; DNA; Hypertrophy; Mitosis; Myocardium; Rats; Thy

1970
Cellular hyperplasia and hypertrophy in cardiomegalies induced by anemia in young and adult rats.
    Circulation research, 1972, Volume: 30, Issue:1

    Topics: Age Factors; Anemia, Hypochromic; Animals; Autoradiography; Body Weight; Cardiomegaly; DNA; Heart Ve

1972
Biochemical correlates of cardiac hypertrophy. V. Labeling of collagen, myosin, and nuclear DNA during experimental myocardial hypertrophy in the rat.
    Circulation research, 1972, Volume: 31, Issue:2

    Topics: Animals; Cardiomegaly; Collagen; Connective Tissue; DNA; Extracellular Space; Female; Hydroxyproline

1972
The role of high-energy phosphate compounds in the development of cardiac hypertrophy.
    Journal of molecular and cellular cardiology, 1972, Volume: 4, Issue:6

    Topics: Acclimatization; Adenosine Triphosphate; Alanine; Animals; Aorta; Atmosphere Exposure Chambers; Carb

1972
The proliferative activity of the heart tissues in various forms of experimental cardiac hypertrophy studied by electron microscope autoradiography.
    Virchows Archiv. B, Cell pathology, 1973, Jan-31, Volume: 12, Issue:2

    Topics: Animals; Aortic Valve Stenosis; Autoradiography; Capillaries; Cardiomegaly; Cell Division; Endotheli

1973
[DNA-synthesis in hearts of rats with renal hypertension after long-term infusion of 3H-thymidin (author's transl)].
    Beitrage zur Pathologie, 1974, Volume: 153, Issue:2

    Topics: Animals; Body Weight; Cardiomegaly; Connective Tissue; Connective Tissue Cells; DNA; Endothelium; Fe

1974