thymidine has been researched along with Carcinoma, Small Cell in 31 studies
Carcinoma, Small Cell: An anaplastic, highly malignant, and usually bronchogenic carcinoma composed of small ovoid cells with scanty neoplasm. It is characterized by a dominant, deeply basophilic nucleus, and absent or indistinct nucleoli. (From Stedman, 25th ed; Holland et al., Cancer Medicine, 3d ed, p1286-7)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The rate of cell proliferation of 99 bronchogenic carcinomas (94 primary tumors and 5 metastases) was evaluated from the labeling index after in vitro incorporation of [3H]thymidine; the rate was then correlated with the histologic tumor type according to the classification of the World Health Organization (WHO)." | 3.65 | Cell proliferation and histologic classification of bronchogenic carcinoma. ( Borgeskov, S; Dombernowsky, P; Hainau, B; Hansen, HH, 1977) |
| "Both sumatriptan and 5-HT inhibit adenylate cyclase activity at doses which correlate with the mitogenic effect." | 1.29 | 5-HT1D receptor type is involved in stimulation of cell proliferation by serotonin in human small cell lung carcinoma. ( Bondiolotti, G; Cattaneo, MG; Palazzi, E; Vicentini, LM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (54.84) | 18.7374 |
| 1990's | 12 (38.71) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Williams, CL | 2 |
| Yokoi, S | 1 |
| Yasui, K | 1 |
| Iizasa, T | 1 |
| Takahashi, T | 1 |
| Fujisawa, T | 1 |
| Inazawa, J | 1 |
| Kerr, KM | 2 |
| Lamb, D | 2 |
| Twentyman, PR | 3 |
| Walls, GA | 1 |
| Wright, KA | 1 |
| Brigham, BA | 1 |
| Moran, RE | 1 |
| Straus, MJ | 1 |
| Cattaneo, MG | 2 |
| Palazzi, E | 1 |
| Bondiolotti, G | 1 |
| Vicentini, LM | 2 |
| Fay, MJ | 1 |
| Friedmann, AS | 1 |
| Yu, XM | 1 |
| North, WG | 1 |
| Ohsaki, Y | 1 |
| Yang, HK | 1 |
| Le, PT | 1 |
| Jensen, RT | 1 |
| Johnson, BE | 1 |
| Maruno, K | 1 |
| Said, SI | 1 |
| Fesce, R | 1 |
| Güzey, M | 2 |
| Demirpençe, E | 1 |
| Criss, W | 1 |
| DeLuca, HF | 2 |
| Codignola, A | 1 |
| Missale, C | 1 |
| Spano, P | 1 |
| Clementi, F | 1 |
| Sher, E | 1 |
| Sattler, C | 1 |
| Shields, AF | 1 |
| Mankoff, DA | 1 |
| Link, JM | 1 |
| Graham, MM | 1 |
| Eary, JF | 1 |
| Kozawa, SM | 1 |
| Zheng, M | 1 |
| Lewellen, B | 1 |
| Lewellen, TK | 1 |
| Grierson, JR | 1 |
| Krohn, KA | 1 |
| Shafer, SH | 1 |
| Phelps, SH | 1 |
| Hainau, B | 1 |
| Dombernowsky, P | 1 |
| Hansen, HH | 2 |
| Borgeskov, S | 1 |
| Marini, AM | 1 |
| Fridman, R | 1 |
| Kanemoto, T | 1 |
| Martin, GR | 1 |
| Guo, Y | 1 |
| Passaniti, A | 1 |
| Macaulay, VM | 1 |
| Smith, IE | 2 |
| Everard, MJ | 2 |
| Teale, JD | 2 |
| Reubi, JC | 1 |
| Millar, JL | 2 |
| McGuire, Wl | 1 |
| Meyer, JS | 1 |
| Barlogie, B | 1 |
| Kute, TE | 1 |
| Maasberg, M | 1 |
| Rotsch, M | 1 |
| Jaques, G | 1 |
| Enderle-Schmidt, U | 1 |
| Weehle, R | 1 |
| Havemann, K | 1 |
| Macauly, VM | 1 |
| Joshi, GP | 1 |
| Weber, S | 1 |
| Zuckerman, JE | 1 |
| Bostwick, DG | 1 |
| Bensch, KG | 1 |
| Sikic, BI | 1 |
| Raffin, TA | 1 |
| Korman, DB | 1 |
| Krutova, TV | 1 |
| Potapov, YN | 1 |
| Pashkova, VS | 1 |
| Viano, I | 1 |
| Silvestro, L | 1 |
| Giaccone, G | 1 |
| Compagnoni, G | 1 |
| Donadio, M | 1 |
| Ferrati, P | 1 |
| Dianzani, C | 1 |
| Genazzani, E | 1 |
| Kwok, TT | 1 |
| Fox, NE | 1 |
| Han, T | 1 |
| Takita, H | 1 |
| Livingston, RB | 1 |
| Ambus, U | 1 |
| George, SL | 1 |
| Freireich, EJ | 1 |
| Hart, JS | 1 |
| Muggia, FM | 1 |
| Krezoski, SK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of 18F FLT PET/CT in Evaluating Early Response to Anti-Proliferative Therapies in Non Small Cell Lung Cancer and Thymic Tumors[NCT01610544] | Phase 2 | 0 participants (Actual) | Interventional | 2012-05-10 | Withdrawn | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for thymidine and Carcinoma, Small Cell
| Article | Year |
|---|---|
Small cell anaplastic carcinoma of the lung. A review of growth characteristics and implications for chemotherapy.
Topics: Autoradiography; Carcinoma, Small Cell; Cell Division; Humans; Lung Neoplasms; Thymidine; Time Facto | 1982 |
30 other studies available for thymidine and Carcinoma, Small Cell
| Article | Year |
|---|---|
Muscarinic signaling in carcinoma cells.
Topics: Calcium; Carcinoma, Small Cell; Cell Adhesion; Cell Line; DNA, Complementary; DNA, Neoplasm; Electro | 2003 |
Down-regulation of SKP2 induces apoptosis in lung-cancer cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Caspase 3; Caspases; Cell Cycle; C | 2003 |
Actual growth rate and tumour cell proliferation in human pulmonary neoplasms.
Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Divis | 1984 |
The response of tumour cells to radiation and cytotoxic drugs--a comparison of clonogenic and isotope uptake assays.
Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Survival; Colony-Forming Units Assay; Do | 1984 |
Labeling indices of human lung cancer. Correlation with histologic type and survival.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Humans; Interp | 1983 |
5-HT1D receptor type is involved in stimulation of cell proliferation by serotonin in human small cell lung carcinoma.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Carcinoma, Small Cell; Cell Division; Colforsin; Hum | 1994 |
Vasopressin and vasopressin-receptor immunoreactivity in small-cell lung carcinoma (SCCL) cell lines: disruption in the activation cascade of V1a-receptors in variant SCCL.
Topics: Calcimycin; Calcium; Carcinoma, Small Cell; Cytosol; Humans; Lung Neoplasms; Receptors, Vasopressin; | 1994 |
Human small cell lung cancer cell lines express functional atrial natriuretic peptide receptors.
Topics: Atrial Natriuretic Factor; Base Sequence; Blotting, Southern; Carcinoma, Small Cell; Cell Division; | 1993 |
VIP inhibits the proliferation of small-cell and nonsmall-cell lung carcinoma.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Count; Cell Division; Cell Line | 1996 |
Evidence for receptor subtype cross-talk in the mitogenic action of serotonin on human small-cell lung carcinoma cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Sma | 1996 |
Effects of retinoic acid (all-trans and 9-cis) on tumor progression in small-cell lung carcinoma.
Topics: Alitretinoin; Apoptosis; Carcinoma, Small Cell; Cell Differentiation; Cell Division; Cell Survival; | 1998 |
Downregulation of nicotinic acetylcholine receptors by nerve growth factor in human small cell lung carcinoma cell lines.
Topics: Carcinoma, Small Cell; Cell Division; Down-Regulation; Humans; Lung Neoplasms; Nerve Growth Factors; | 1998 |
Combinational effects of vitamin D3 and retinoic acid (all trans and 9 cis) on proliferation, differentiation, and programmed cell death in two small cell lung carcinoma cell lines.
Topics: Alitretinoin; Apoptosis; Carcinoma, Small Cell; Cell Differentiation; Cell Division; Cholecalciferol | 1998 |
Carbon-11-thymidine and FDG to measure therapy response.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carbon Radioisotopes; Carcinoma, Small Cell; Fluorin | 1998 |
Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Caffeine; Calcium; Carcinoma, Small Cell; Cell Survival; Cyclic | 1998 |
Cell proliferation and histologic classification of bronchogenic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cel | 1977 |
The neurotoxin 1-methyl-4-phenylpyridinium: a selective cytostatic agent in small-cell lung cancer cell lines with neuroendocrine properties.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antineoplastic Agents; Carcinoma, Small Cell; DNA, Neoplasm; G | 1992 |
Experimental and clinical studies with somatostatin analogue octreotide in small cell lung cancer.
Topics: Animals; Carcinoma, Small Cell; Cell Line; Cell Survival; DNA Replication; Humans; Lung Neoplasms; M | 1991 |
Impact of flow cytometry on predicting recurrence and survival in breast cancer patients.
Topics: Analysis of Variance; Aneuploidy; Breast Neoplasms; Bromodeoxyuridine; Carcinoma, Small Cell; Cell C | 1985 |
Androgen receptors, androgen-dependent proliferation, and 5 alpha-reductase activity of small-cell lung cancer cell lines.
Topics: Androgen Antagonists; Androgens; Carcinoma, Small Cell; Cell Division; Cell Line; Centrifugation, De | 1989 |
Somatomedin-C/insulin-like growth factor-I is a mitogen for human small cell lung cancer.
Topics: Adenocarcinoma; Carcinoma, Small Cell; DNA; Humans; Insulin-Like Growth Factor I; Lung Neoplasms; Ma | 1988 |
A comparison of patient survival and tumour growth kinetics in human bronchogenic carcinoma.
Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Divis | 1988 |
Gastrin releasing peptide is a selective mitogen for small cell lung carcinoma in vitro.
Topics: Carcinoma, Small Cell; Cell Count; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Microscopy, El | 1985 |
The study of the cytotoxic effect of anticancer drugs on human lung tumors transplanted to mice by use of diffusion chambers.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Dif | 1985 |
In vitro evaluation of myelotoxicity induced by antineoplastic drugs.
Topics: Antineoplastic Agents; Bone Marrow; Carcinoma, Small Cell; Humans; In Vitro Techniques; Leukocyte Co | 1986 |
Use of a tritiated thymidine suicide technique in the study of the cytotoxic drug response of cells located at different depths within multicellular spheroids.
Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Cycle; Cell Line; Cell Separation; Cell | 1987 |
A comparison of clonogenic and radionuclide uptake assays for determining the radiation response of human small-cell lung cancer xenografts and cell lines.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line; Cell Survival; Dose-Response Relat | 1987 |
Immunologic impairment in bronchogenic carcinoma: a study of lymphocyte response to phytohemagglutinin.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Carcinoma; Carcinoma, Bronchogenic | 1972 |
In vitro determination of thymidine-3H labeling index in human solid tumors.
Topics: Autoradiography; Carcinoma, Small Cell; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm | 1974 |
Cell kinetic studies in patients with small cell carcinoma of the lung.
Topics: Autoradiography; Biopsy; Bone Marrow; Carcinoma, Small Cell; Cell Division; Cyclohexanes; Cyclophosp | 1974 |