Page last updated: 2024-11-06

thymidine and Cancer of Pituitary

thymidine has been researched along with Cancer of Pituitary in 35 studies

Research Excerpts

ExcerptRelevanceReference
"Human pituitary adenoma cells and rat pituitary cell line (GH3) were cultured and treated in vitro with octreotide and the broad-spectrum SST agonist SOM230 (pasireotide)."3.73Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours. ( Ciccarelli, E; Czirják, S; Gaia, D; Góth, MI; Grossman, AB; Hanson, MR; Hanzély, Z; Hubina, E; Jordan, S; Khalaf, S; Korbonits, M; Losa, M; Nagy, GM; Nanzer, AM; Papotti, M; Terreni, MR, 2006)
" The effect of inhibition of tyrosine kinase activity on thymidine uptake into cultured human pituitary adenoma cells was studied using two inhibitors, genestein and methyl-2,3-dihydroxycinnamate (MDHC)."3.69Suppression of tyrosine kinase activity inhibits [3H]thymidine uptake in cultured human pituitary tumor cells. ( Jones, TH; Justice, SK; Price, A, 1997)
"Among these, the growth fraction of pituitary adenomas has been determined by different methods, of which the most useful are those performed in archival material."1.30Usefulness of markers of cell proliferation in the management of pituitary adenomas. ( Franzin, A; Giovanelli, M; Losa, M; Mangili, F; Mortini, P; Terreni, MR, 1998)
"The most effective therapy of human prolactinomas is represented by dopamine D-2 receptor agonists; there is, however, a population of nonresponder patients who require surgical intervention."1.29Nerve growth factor suppresses the transforming phenotype of human prolactinomas. ( Balsari, A; Boroni, F; Dal Toso, R; Giovanelli, M; Losa, M; Missale, C; Spano, P; Zanellato, A, 1993)
" To determine whether the inabilities of TAM to stimulate cell proliferation and induce PR were a function of TAM concentration, dose-response experiments were performed."1.28The estrogenic and antiestrogenic properties of tamoxifen in GH4C1 pituitary tumor cells are gene specific. ( Baldwin, TM; Beams, FE; Gilchrist, CA; Hrbek, MJ; Shull, JD, 1992)
"MtT/W15 transplantable pituitary tumors from rats treated for 3 weeks with DES showed significant reduction in the extent of [3H]thymidine incorporation compared with tumor cells from untreated rats (2231 +/- 182 vs 172 +/- 17 dpm/10(5) cells; n = 3)."1.27Prolactin and growth hormone synthesis and thymidine incorporation in dissociated rat pituitary tumor cells. ( Coleman, K; Lloyd, RV; Schmidt, K; Wilson, BS, 1986)

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199015 (42.86)18.7374
1990's16 (45.71)18.2507
2000's4 (11.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Florio, T2
Barbieri, F1
Spaziante, R2
Zona, G2
Hofland, LJ1
van Koetsveld, PM1
Feelders, RA1
Stalla, GK1
Theodoropoulou, M1
Culler, MD2
Dong, J1
Taylor, JE1
Moreau, JP1
Saveanu, A2
Gunz, G1
Dufour, H1
Jaquet, P2
Hubina, E1
Nanzer, AM1
Hanson, MR1
Ciccarelli, E1
Losa, M3
Gaia, D1
Papotti, M1
Terreni, MR2
Khalaf, S1
Jordan, S1
Czirják, S1
Hanzély, Z1
Nagy, GM1
Góth, MI1
Grossman, AB1
Korbonits, M1
Resmini, E1
Dadati, P1
Ravetti, JL1
Bianchi, F1
Rebora, A1
Minuto, F1
Ferone, D1
Svec, F1
Pharaboz, MO1
Morel, Y1
Andre, J1
Senogles, SE1
Caronti, B1
Palladini, G1
Calderaro, C1
Bevilacqua, MG1
Petrangeli, E1
Esposito, V1
Tamburrano, G1
Gulino, A1
Jaffrain-Rea, ML1
Kunert-Radek, J1
Stepień, H1
Pawlikowski, M1
Alvarez, CV1
Zalvide, JB1
Cancio, E1
Dieguez, C1
Regueiro, BJ1
Vega, FV1
Dominguez, F1
Missale, C1
Boroni, F1
Giovanelli, M2
Zanellato, A1
Dal Toso, R1
Balsari, A1
Spano, P1
Lewis, MD1
Webster, J1
Ham, J1
Davies, JS1
Scanlon, MF1
Jones, TH1
Justice, SK1
Price, A1
Honegger, J1
Renner, C1
Fahlbusch, R1
Adams, EF1
Díaz-Torga, G1
González Iglesias, A1
Achával-Zaia, R1
Libertun, C1
Becú-Villalobos, D1
Franzin, A1
Mortini, P1
Mangili, F1
Li, H1
Robinson, PJ1
Kawashima, S1
Funder, JW1
Liu, JP1
Danila, DC1
Inder, WJ1
Zhang, X1
Alexander, JM1
Swearingen, B1
Hedley-Whyte, ET1
Klibanski, A1
Biswas, DK2
Lyons, J1
Tashjian, AH1
Abdullah, KT1
Brennessel, BA1
Pan, MG1
Newman, B1
Hershberger, RE1
Civelli, O1
Stork, PJ1
Duchemin, AM1
Enyeart, JA1
Biagi, BA1
Foster, DN1
Mlinar, B1
Enyeart, JJ1
Shull, JD1
Beams, FE1
Baldwin, TM1
Gilchrist, CA1
Hrbek, MJ1
Reynolds, AM1
Surks, MI2
Shapiro, LE2
Mackanos, EA1
Pettit, GR1
Ramsdell, JS1
Melmed, S1
Fagin, J1
Leung, M1
Patel, KR1
Lloyd, RV1
Schmidt, K1
Coleman, K1
Wilson, BS1
Boeryd, B1
Eriksson, O1
Knutson, F1
Lundin, PM1
Norrby, K1
Dingemans, KP1
Biswas, S1
Hollander, VP1
Church, RL1
Consigli, RA1
Vanha-Perttula, T1
Kohler, PO1
Frohman, LA1
Messier, B2
Clifton, KH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Predictive Value of 3 Months Results on 12 Months Tumor Shrinkage After First-Line Octreotide-LAR Therapy in Patients With Acromegaly[NCT00616408]61 participants (Actual)Observational1997-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

35 other studies available for thymidine and Cancer of Pituitary

ArticleYear
Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study.
    Endocrine-related cancer, 2008, Volume: 15, Issue:2

    Topics: Adenoma; Adult; Aged; Antineoplastic Agents, Hormonal; Cabergoline; Cell Division; Dopamine; Dopamin

2008
Somatostatin analogues stimulate p27 expression and inhibit the MAP kinase pathway in pituitary tumours.
    European journal of endocrinology, 2006, Volume: 155, Issue:2

    Topics: Adenoma; Animals; Antineoplastic Agents, Hormonal; Cell Division; Cell Line, Tumor; Cyclin-Dependent

2006
Rapid pituitary tumor shrinkage with dissociation between antiproliferative and antisecretory effects of a long-acting octreotide in an acromegalic patient.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:5

    Topics: Acromegaly; Adenoma, Acidophil; Adult; Cabergoline; Cell Proliferation; Cells, Cultured; Delayed-Act

2007
Glucocorticoids inhibit the growth of AtT-20 mouse pituitary tumor cells.
    Molecular and cellular endocrinology, 1984, Volume: 35, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Cell Division; Cell Line; Dexamethasone; DNA, Neoplasm; Glucoc

1984
Dual effects of estradiol on normal and tumor pituitary cell multiplication.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:1

    Topics: Animals; Cell Division; Cells, Cultured; DNA; Estradiol; Male; Pituitary Gland, Anterior; Pituitary

1984
The D2 dopamine receptor mediates inhibition of growth in GH4ZR7 cells: involvement of protein kinase-C epsilon.
    Endocrinology, 1994, Volume: 134, Issue:2

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Alprenolol; Animals; Apomorphine; Benzaz

1994
Effects of gonadal steroids on the growth of human pituitary adenomas in vitro.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1995, Volume: 16, Issue:6

    Topics: Adenoma; Adult; Androgens; Bromocriptine; Cell Division; Dihydrotestosterone; Estradiol; Female; Fol

1995
Inhibition of rat pituitary tumor cell proliferation by benzodiazepines in vitro.
    Neuroendocrinology, 1994, Volume: 59, Issue:1

    Topics: Animals; Benzodiazepines; Cell Division; DNA, Neoplasm; Dose-Response Relationship, Drug; Female; Li

1994
Regulation of prothymosin alpha mRNA levels in rat pituitary tumor cells.
    Neuroendocrinology, 1993, Volume: 57, Issue:6

    Topics: Actins; Adolescent; Animals; Blotting, Northern; Caprylates; Cell Cycle; Cricetinae; Culture Media,

1993
Nerve growth factor suppresses the transforming phenotype of human prolactinomas.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Sep-01, Volume: 90, Issue:17

    Topics: Animals; Binding, Competitive; Bromocriptine; Cell Division; Cell Membrane; Humans; Kinetics; Mice;

1993
AMP is a component of the low molecular weight mitogenic activity present in human pituitary tumours.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:3

    Topics: Adenosine Monophosphate; Animals; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liqu

1996
Suppression of tyrosine kinase activity inhibits [3H]thymidine uptake in cultured human pituitary tumor cells.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:7

    Topics: Adenoma; Adult; Aged; Animals; Cell Division; Cinnamates; Culture Media, Conditioned; Enzyme Inhibit

1997
Progesterone receptor gene expression in craniopharyngiomas and evidence for biological activity.
    Neurosurgery, 1997, Volume: 41, Issue:6

    Topics: Adolescent; Adult; Child; Craniopharyngioma; Estradiol; Female; Gene Expression; Humans; Male; Middl

1997
Angiotensin II-induced Ca2+ mobilization and prolactin release in normal and hyperplastic pituitary cells.
    The American journal of physiology, 1998, Volume: 274, Issue:3

    Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; DNA Replication; Estrogens; Female; Hyperplasia;

1998
Usefulness of markers of cell proliferation in the management of pituitary adenomas.
    Clinical science (London, England : 1979), 1998, Volume: 95, Issue:2

    Topics: Adenoma; Antibodies, Monoclonal; Biomarkers, Tumor; Cell Cycle; Cell Division; Flow Cytometry; Human

1998
Differential regulation of MAP kinase activity by corticotropin-releasing hormone in normal and neoplastic corticotropes.
    The international journal of biochemistry & cell biology, 1998, Volume: 30, Issue:12

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Calcium-Calmodulin-Depen

1998
Activin effects on neoplastic proliferation of human pituitary tumors.
    The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:3

    Topics: Activin Receptors; Activins; Adenoma; Adult; Aged; Aged, 80 and over; Blotting, Western; Cell Divisi

2000
Induction of prolactin synthesis in rat pituitary tumor cells by 5-bromodeoxyuridine.
    Cell, 1977, Volume: 11, Issue:2

    Topics: Animals; Bromodeoxyuridine; Cell Line; Clone Cells; Growth Hormone; Pituitary Neoplasms; Prolactin;

1977
On the mechanism of 5-bromodeoxyuridine induction of prolactin synthesis in rat pituitary tumor cells.
    The Journal of cell biology, 1979, Volume: 81, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Line; DNA, Neoplasm; Pituitary Neoplasms; Prolactin; Rats; Thymidin

1979
Dopaminergic inhibition of DNA synthesis in pituitary tumor cells is associated with phosphotyrosine phosphatase activity.
    The Journal of biological chemistry, 1992, Dec-05, Volume: 267, Issue:34

    Topics: Adenylyl Cyclases; Animals; Biological Transport; DNA Replication; DNA, Neoplasm; Dopamine; Haloperi

1992
Ca2+ channel modulation and kinase-C activation in a pituitary cell line: induction of immediate early genes and inhibition of proliferation.
    Molecular endocrinology (Baltimore, Md.), 1992, Volume: 6, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1992
The estrogenic and antiestrogenic properties of tamoxifen in GH4C1 pituitary tumor cells are gene specific.
    Molecular endocrinology (Baltimore, Md.), 1992, Volume: 6, Issue:4

    Topics: Actins; Animals; Cell Division; Cell Line; DNA Replication; Estradiol; Gene Expression Regulation, N

1992
The effects of chronic exposure to supraphysiological concentrations of 3, 5, 3' triiodo-L-thyronine (T3) on cultured GC cells.
    Journal of cellular physiology, 1991, Volume: 149, Issue:3

    Topics: Animals; Cell Division; Cell Line; Cell Survival; DNA Replication; Growth Hormone; Hot Temperature;

1991
Bryostatins selectively regulate protein kinase C-mediated effects on GH4 cell proliferation.
    The Journal of biological chemistry, 1991, Jun-15, Volume: 266, Issue:17

    Topics: Animals; Antineoplastic Agents; Bryostatins; Cell Adhesion; Cell Cycle; Cell Division; Cell Line; DN

1991
Bromocriptine inhibits incorporation of [3H]thymidine into rat pituitary tumor cells.
    Brain research, 1986, Mar-26, Volume: 369, Issue:1-2

    Topics: Animals; Bromocriptine; Clone Cells; DNA, Neoplasm; Pituitary Neoplasms; Prolactin; Rats; Receptors,

1986
The rate of appearance of thyroid hormone nuclear receptor is increased during deoxyribose nucleic acid synthesis in GC cells: analysis of thymidine-treated GC cells using dense amino acid labeling.
    Endocrinology, 1986, Volume: 119, Issue:5

    Topics: Animals; Cell Line; Cell Nucleus; DNA Replication; Kinetics; Pituitary Neoplasms; Rats; Receptors, T

1986
Prolactin and growth hormone synthesis and thymidine incorporation in dissociated rat pituitary tumor cells.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1986, Volume: 181, Issue:1

    Topics: Animals; Diethylstilbestrol; Estrogens; Female; Growth Hormone; In Vitro Techniques; Pituitary Gland

1986
On the viability of tumour cells in artificially produced suspensions.
    Acta pathologica et microbiologica Scandinavica, 1965, Volume: 65, Issue:4

    Topics: Adenine; Animals; Autoradiography; Cell Division; DNA, Neoplasm; In Vitro Techniques; Methylcholanth

1965
The development of TSH producing pituitary tumours in the mouse.
    Virchows Archiv. B, Cell pathology, 1973, Mar-30, Volume: 12, Issue:4

    Topics: Animals; Autoradiography; Cell Count; Cell Nucleus; Cilia; Endoplasmic Reticulum; Endothelium; Macro

1973
Metabolic studies on mammary tumor MTW9 following resection of the mammosomatotropic tumor MtTW5.
    Cancer research, 1971, Volume: 31, Issue:10

    Topics: Aminoisobutyric Acids; Animals; Carbon Isotopes; DNA, Neoplasm; Glycine; In Vitro Techniques; Mammar

1971
DNA fragmentation in a clonal line of rat pituitary tumor (GH1 strain).
    Biochemical and biophysical research communications, 1971, Jan-08, Volume: 42, Issue:1

    Topics: Animals; Cell Line; Centrifugation, Density Gradient; Clone Cells; DNA Replication; DNA, Neoplasm; P

1971
Effect of insulin on growth hormone (GH) induction by cortisol in rat pituitary tumor cells.
    Life sciences. Pt. 2: Biochemistry, general and molecular biology, 1970, Jul-22, Volume: 9, Issue:14

    Topics: Animals; Cell Line; Culture Techniques; DNA; Drug Synergism; Growth Hormone; Hydrocortisone; Insulin

1970
Correlation between mitotic activity and transplantability of pituitary tumors following radiothyroidectomy.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1969, Volume: 130, Issue:4

    Topics: Animals; Female; Injections, Intraperitoneal; Iodine Isotopes; Male; Methods; Mice; Mitosis; Pituita

1969
Effect of exogenous thyroxine on 3H-thymidine uptake in mouse pituitary gland.
    Acta endocrinologica, 1969, Volume: 61, Issue:1

    Topics: Animals; Depression, Chemical; Female; Mice; Pituitary Gland; Pituitary Neoplasms; Thymidine; Thyroi

1969
Cell population kinetics during the induction of thyrotropic pituitary tumors.
    Cancer research, 1966, Volume: 26, Issue:3

    Topics: Animals; Cell Division; Mice; Neoplasms, Experimental; Pituitary Gland; Pituitary Neoplasms; RNA; Th

1966