thymidine has been researched along with Cancer of Lung in 189 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the usefulness of 3'-deoxy-3'-[18F]fluorothymidine (FLT)-positron emission tomography (PET) for predicting response and patient outcome of gefitinib therapy in patients with adenocarcinoma of the lung." | 7.74 | [18F]Fluorothymidine positron emission tomography before and 7 days after gefitinib treatment predicts response in patients with advanced adenocarcinoma of the lung. ( Im, KC; Kim, SW; Lee, DH; Lee, JS; Moon, DH; Oh, SJ; Ryu, JS; Sohn, HJ; Suh, C; Yang, YJ, 2008) |
| "Hypoxanthine:guanine phosphoribosyltransferase (HPRT) activity was measured in 14 human osteosarcomas to test whether a subset of these tumors was deficient in the purine salvage pathway enzyme and thus provide a rationale for therapy with methotrexate-thymidine rescue." | 7.67 | Hypoxanthine:guanine phosphoribosyltransferase activity in primary human osteosarcomas. A rationale for therapy with methotrexate-thymidine rescue? ( Houghton, JA; Houghton, PJ; Meyer, WH, 1987) |
| "Many clinical studies have been conducted on the role of high-dose methotrexate (MTX) in human osteosarcoma, but information about the in vitro effect of MTX on human osteosarcoma cells is lacking." | 7.66 | Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate. ( Chacón, RD; Filmus, J; Mordoh, J, 1981) |
| " The toxic effects of thymidylate synthase inhibition may be prevented by salvage of exogenous thymidine." | 5.27 | Potentiation of quinazoline antifolate (CB3717) toxicity by dipyridamole in human lung carcinoma, A549, cells. ( Curtin, NJ; Harris, AL, 1988) |
| "To evaluate the usefulness of 3'-deoxy-3'-[18F]fluorothymidine (FLT)-positron emission tomography (PET) for predicting response and patient outcome of gefitinib therapy in patients with adenocarcinoma of the lung." | 3.74 | [18F]Fluorothymidine positron emission tomography before and 7 days after gefitinib treatment predicts response in patients with advanced adenocarcinoma of the lung. ( Im, KC; Kim, SW; Lee, DH; Lee, JS; Moon, DH; Oh, SJ; Ryu, JS; Sohn, HJ; Suh, C; Yang, YJ, 2008) |
| "The influence of serum-free media, previously conditioned by A-549 line cells of the human lung adenocarcinoma (c-medium), on the intensity of 3H-thymidine incorporation into DNA of the same cells was studied." | 3.68 | [The autocrine regulation of the proliferation of cell line A-549 under conditions facilitating the acidification of the culture medium]. ( Garas'ko, SI; Kusen', SI; Shafranskaia, GI; Stoĭka, RS; Sushel'nitskiĭ, SI, 1992) |
| "Hypoxanthine:guanine phosphoribosyltransferase (HPRT) activity was measured in 14 human osteosarcomas to test whether a subset of these tumors was deficient in the purine salvage pathway enzyme and thus provide a rationale for therapy with methotrexate-thymidine rescue." | 3.67 | Hypoxanthine:guanine phosphoribosyltransferase activity in primary human osteosarcomas. A rationale for therapy with methotrexate-thymidine rescue? ( Houghton, JA; Houghton, PJ; Meyer, WH, 1987) |
| "Many clinical studies have been conducted on the role of high-dose methotrexate (MTX) in human osteosarcoma, but information about the in vitro effect of MTX on human osteosarcoma cells is lacking." | 3.66 | Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate. ( Chacón, RD; Filmus, J; Mordoh, J, 1981) |
| " We have determined: (1) tritiated thymidine (3H-TdR) incorporation throughout S-phase in Lewis lung tumor cells in vitro both before and after treatment with cytosine arabinoside; (2) 3H-TdR incorporation throughout S-phase in KHT tumor cells in vitro and in vivo; (3) 3H-TdR incorporation throughout S-phase in Chinese hamster ovary cells and compared it with DNA synthesis throughout S-phase; (4) a mathematical expression describing 3H-TdR incorporation throughout S-phase in Chinese hamster M3-1 cells; and (5) the simultaneous incorporation of 3H-TdR and 35S-methionine as they are related to cell size and DNA content in S49 mouse lymphoma cells." | 3.66 | Rates of incorporation of radioactive molecules during the cell cycle. ( Dean, PN; George, YS; Gray, JW; Groppi, V; Look, M; Pallavicini, MG, 1981) |
| "The chemotherapeutic activity of thymidine (dThd) was tested against four human tumor xenografts growing in nude mice, including a melanoma, an oat cell carcinoma of the lung, a colon carcinoma, and a breast carcinoma." | 3.66 | Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice. ( Howell, SB; Jenkins, RS; Streifel, J, 1979) |
| " injection of caffeine (8, 20, and 40 mg/kg) 3 times weekly for 8 weeks suppressed the development of spontaneous pulmonary adenomas in strain A mice." | 3.66 | Inhibiting effect of caffeine on spontaneous and urethan-induced lung tumors in strain A mice. ( Shimkin, MB; Theiss, JC, 1978) |
| "The rate of cell proliferation of 99 bronchogenic carcinomas (94 primary tumors and 5 metastases) was evaluated from the labeling index after in vitro incorporation of [3H]thymidine; the rate was then correlated with the histologic tumor type according to the classification of the World Health Organization (WHO)." | 3.65 | Cell proliferation and histologic classification of bronchogenic carcinoma. ( Borgeskov, S; Dombernowsky, P; Hainau, B; Hansen, HH, 1977) |
| "Noncurative excision of a primary sc Lewis lung tumor performed on Day 7 or later results in an increase in the thymidine index and growth rate with minimal changes in the cell cycle parameters of the lung metastases." | 3.65 | Effects of surgery on the cell kinetics of residual tumor. ( Holmquist, JP; Simpson-Herren, L, 1976) |
| "The value of the labelling index (incubation with H3-thymidine) was compared with the doubling time of tumour volume (by repeated roentgenograms) for 3 tumours of human lungs: two squamous cell carcinomas taken at various differentiation levels and a hamartoma." | 3.65 | [The relationship between the doubling time of human lung tumor volume and the labelling index]. ( Aksiutina, MS; Korman, DB; Krutova, TV; Liashchenko, VI; Lipchina, LP, 1976) |
| "The purpose of this study was to investigate the utility of plasma pharmacokinetic and pharmacodynamic measures including plasma deoxynucleosides, homocysteine and methylmalonic acid concentrations in understanding the time course and extent of the inhibition of thymidylate synthase (TS) by pemetrexed in the context of a phase I/II combination study with vinorelbine." | 2.73 | Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules. ( Clarke, SJ; Li, KM; Rivory, LP, 2007) |
| " This study assesses the dose-dependent effect of N-acetylcysteine (NAC), a chemopreventive agent, in combination with vitamin C (VC) on the activity of ODC in lung carcinoma cell line, NCI-H82." | 1.33 | The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells--In vitro. ( Shyamaladevi, CS; Vanisree, AJ, 2006) |
| "It can be concluded that the linear-quadratic analysis of dose-response relationships offers insights into the correlation between cell survival and induction of exchanges in non-sensitized and radiosensitized cells." | 1.30 | Correlation between cell reproductive death and chromosome aberrations assessed by FISH for low and high doses of radiation and sensitization by iodo-deoxyuridine in human SW-1573 cells. ( Barendsen, GW; Darroudi, F; Franken, NA; Kipp, JB; Ludwików, G; Ruurs, P; van Bree, C, 1999) |
| "Both sumatriptan and 5-HT inhibit adenylate cyclase activity at doses which correlate with the mitogenic effect." | 1.29 | 5-HT1D receptor type is involved in stimulation of cell proliferation by serotonin in human small cell lung carcinoma. ( Bondiolotti, G; Cattaneo, MG; Palazzi, E; Vicentini, LM, 1994) |
| "Suramin treatment resulted in a time- and dose-dependent decrease in [3H]thymidine incorporation, except in one adenocarcinoma cell line where DNA synthesis was highly stimulated." | 1.29 | In vitro effect of suramin on lung tumour cells. ( Lauber, B; Mórocz, IA; Schmitter, D; Stahel, RA, 1993) |
| "We have compared the ability of cancer tissue to proliferate in native-state culture to the stage and histological grade of four major types of human carcinomas: breast, ovarian, colon, and lung." | 1.28 | Cancer biology for individualized therapy: correlation of growth fraction index in native-state histoculture with tumor grade and stage. ( Bordin, GM; Connors, KM; Hoffman, RM; Robb, JA; Umbreit, JN; Vescio, RA; Youngkin, T, 1990) |
| "The ability to form spontaneous metastasis (SM) in the lungs and in other organs appears among cell variants isolated at days 10 to 21 after inoculation." | 1.27 | Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity. ( Deichman, GI; Vendrov, EL, 1986) |
| " The toxic effects of thymidylate synthase inhibition may be prevented by salvage of exogenous thymidine." | 1.27 | Potentiation of quinazoline antifolate (CB3717) toxicity by dipyridamole in human lung carcinoma, A549, cells. ( Curtin, NJ; Harris, AL, 1988) |
| "tumor, spontaneous metastases, and lung colonies formed after i." | 1.26 | Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma. ( Cuman, R; Giraldi, T; Lassiani, L; Nisi, C; Sava, G, 1981) |
| "Fourteen of 20 lung cancer patients responded to lung cancer antigen, whereas only 11 of 41 patients with other tumors and 3 of 19 normal subjects reacted." | 1.26 | A rapid assay for stimulation of human lymphocytes by tumor-associated antigens. ( Grimm, EA; Morton, DL; Roth, JA, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 107 (56.61) | 18.7374 |
| 1990's | 44 (23.28) | 18.2507 |
| 2000's | 25 (13.23) | 29.6817 |
| 2010's | 11 (5.82) | 24.3611 |
| 2020's | 2 (1.06) | 2.80 |
| Authors | Studies |
|---|---|
| Mercer, JR | 2 |
| Xu, LH | 1 |
| Knaus, EE | 2 |
| Wiebe, LI | 2 |
| Long, F | 1 |
| Li, Z | 1 |
| Wei, Z | 1 |
| Xie, Y | 1 |
| Virgilio, A | 1 |
| Benigno, D | 1 |
| Pecoraro, A | 1 |
| Russo, A | 1 |
| Russo, G | 1 |
| Esposito, V | 1 |
| Galeone, A | 1 |
| Chen, X | 2 |
| Yang, Y | 2 |
| Katz, SI | 2 |
| Lowe, FJ | 1 |
| Luettich, K | 1 |
| Gregg, EO | 1 |
| Lee, SJ | 2 |
| Yeo, JS | 1 |
| Lee, HJ | 2 |
| Lee, EJ | 1 |
| Kim, SY | 3 |
| Jang, SJ | 1 |
| Lee, JJ | 1 |
| Ryu, JS | 3 |
| Moon, DH | 3 |
| Lee, JS | 2 |
| Kang, JH | 1 |
| Lee, SH | 1 |
| Lee, CH | 1 |
| Son, J | 1 |
| Berger, I | 1 |
| Khalid, U | 1 |
| Patel, A | 1 |
| Cai, J | 1 |
| Farwell, MD | 1 |
| Langer, C | 1 |
| Aggarwal, C | 1 |
| Albelda, SM | 1 |
| Sohn, HJ | 1 |
| Yang, YJ | 1 |
| Oh, SJ | 2 |
| Im, KC | 1 |
| Lee, DH | 1 |
| Suh, C | 1 |
| Kim, SW | 2 |
| Thomas, HD | 1 |
| Saravanan, K | 1 |
| Wang, LZ | 1 |
| Lin, MJ | 1 |
| Northen, JS | 1 |
| Barlow, H | 1 |
| Barton, M | 1 |
| Newell, DR | 2 |
| Griffin, RJ | 1 |
| Golding, BT | 1 |
| Curtin, NJ | 4 |
| Yannelli, JR | 1 |
| Tucker, JA | 1 |
| Hidalgo, G | 1 |
| Perkins, S | 1 |
| Kryscio, R | 1 |
| Hirschowitz, EA | 1 |
| Walker, AM | 1 |
| Stevens, JJ | 1 |
| Ndebele, K | 1 |
| Tchounwou, PB | 1 |
| Zhang, HY | 1 |
| Liu, ZG | 1 |
| Zhang, Z | 1 |
| Gong, HY | 1 |
| Mileshkin, L | 1 |
| Hicks, RJ | 1 |
| Hughes, BG | 1 |
| Mitchell, PL | 1 |
| Charu, V | 1 |
| Gitlitz, BJ | 1 |
| Macfarlane, D | 1 |
| Solomon, B | 1 |
| Amler, LC | 1 |
| Yu, W | 1 |
| Pirzkall, A | 1 |
| Fine, BM | 1 |
| Sirbu, BM | 1 |
| Lachmayer, SJ | 1 |
| Wülfing, V | 1 |
| Marten, LM | 1 |
| Clarkson, KE | 1 |
| Lee, LW | 1 |
| Gheorghiu, L | 1 |
| Zou, L | 1 |
| Powell, SN | 1 |
| Dahm-Daphi, J | 1 |
| Willers, H | 1 |
| Minamimoto, R | 1 |
| Toyohara, J | 1 |
| Seike, A | 1 |
| Ito, H | 1 |
| Endo, H | 1 |
| Morooka, M | 1 |
| Nakajima, K | 1 |
| Mitsumoto, T | 1 |
| Ito, K | 1 |
| Okasaki, M | 1 |
| Ishiwata, K | 2 |
| Kubota, K | 1 |
| Kim, EJ | 1 |
| Ahn, JH | 1 |
| Kudryavtsev, IA | 1 |
| Golenko, OD | 1 |
| Gudkova, MV | 1 |
| Myasishcheva, NV | 1 |
| Baguley, BC | 1 |
| Marshall, ES | 1 |
| Christmas, TI | 1 |
| Black, CA | 1 |
| Ucci, JW | 1 |
| Vorpagel, JS | 1 |
| Mauck, MC | 1 |
| Fenlon, EE | 1 |
| Lee, CT | 1 |
| Park, KH | 1 |
| Adachi, Y | 1 |
| Seol, JY | 1 |
| Yoo, CG | 1 |
| Kim, YW | 1 |
| Han, SK | 1 |
| Shim, YS | 1 |
| Coffee, K | 1 |
| Dikov, MM | 1 |
| Carbone, DP | 1 |
| Godschalk, R | 1 |
| Nair, J | 1 |
| van Schooten, FJ | 1 |
| Risch, A | 1 |
| Drings, P | 1 |
| Kayser, K | 1 |
| Dienemann, H | 1 |
| Bartsch, H | 1 |
| Pfeifer, GP | 1 |
| Hainaut, P | 1 |
| Yokoi, S | 1 |
| Yasui, K | 1 |
| Iizasa, T | 1 |
| Takahashi, T | 2 |
| Fujisawa, T | 1 |
| Inazawa, J | 1 |
| FOLEY, WA | 1 |
| COLE, LJ | 1 |
| INGRAM, BJ | 1 |
| CROCKER, TT | 2 |
| TRAININ, N | 2 |
| KAYE, AM | 2 |
| BERENBLUM, I | 2 |
| Zhou, J | 1 |
| Chen, J | 1 |
| Mokotoff, M | 1 |
| Zhong, R | 1 |
| Shultz, LD | 1 |
| Ball, ED | 1 |
| Castro, M | 1 |
| Kang, Y | 1 |
| Hebron, H | 1 |
| Ozbun, L | 1 |
| Mariano, J | 1 |
| Minoo, P | 1 |
| Jakowlew, SB | 1 |
| Moody, TW | 1 |
| Czerwinski, G | 1 |
| Tarasova, NI | 1 |
| Moody, DL | 1 |
| Michejda, CJ | 1 |
| Lafleur, EA | 1 |
| Koshkina, NV | 1 |
| Stewart, J | 1 |
| Jia, SF | 1 |
| Worth, LL | 1 |
| Duan, X | 1 |
| Kleinerman, ES | 1 |
| Leśnikowski, ZJ | 1 |
| Paradowska, E | 1 |
| Olejniczak, AB | 1 |
| Studzińska, M | 1 |
| Seekamp, P | 1 |
| Schüssler, U | 1 |
| Gabel, D | 1 |
| Schinazi, RF | 1 |
| Plesek, J | 1 |
| Mazzarino, C | 1 |
| Nicosia, A | 1 |
| Garraffo, C | 1 |
| Tantillo, F | 1 |
| Monte, V | 1 |
| Girlando, A | 1 |
| Malaponte, G | 1 |
| Vanisree, AJ | 1 |
| Shyamaladevi, CS | 1 |
| Thejass, P | 1 |
| Kuttan, G | 1 |
| Senogles, SE | 1 |
| Brockenbrough, JS | 1 |
| Rasey, JS | 1 |
| Grierson, JR | 2 |
| Wiens, LW | 1 |
| Vesselle, H | 1 |
| Li, KM | 1 |
| Rivory, LP | 1 |
| Clarke, SJ | 1 |
| Kerr, KM | 3 |
| Lamb, D | 3 |
| Twentyman, PR | 4 |
| Walls, GA | 1 |
| Wright, KA | 1 |
| Brigham, BA | 1 |
| Moran, RE | 1 |
| Straus, MJ | 3 |
| Wheeler, RH | 1 |
| Clauw, DJ | 1 |
| Natale, RB | 1 |
| Ruddon, RW | 1 |
| Shimizu, T | 1 |
| Giraldi, T | 2 |
| Sava, G | 2 |
| Nisi, C | 2 |
| Robertson, AM | 1 |
| D'Incalci, M | 1 |
| Erba, E | 1 |
| Vaghi, M | 1 |
| Morasca, L | 1 |
| Leibovici, J | 1 |
| Susskind-Brudner, G | 1 |
| Wolman, M | 1 |
| Mordoh, J | 1 |
| Chacón, RD | 1 |
| Filmus, J | 1 |
| Gray, JW | 1 |
| Pallavicini, MG | 1 |
| George, YS | 1 |
| Groppi, V | 1 |
| Look, M | 1 |
| Dean, PN | 1 |
| Cuman, R | 1 |
| Lassiani, L | 1 |
| Heston, WD | 1 |
| Kadmon, D | 1 |
| Fair, WR | 1 |
| Wang, ZX | 1 |
| Xu, PS | 1 |
| Shen, RM | 1 |
| Lin, JF | 1 |
| Sun, Y | 1 |
| Zhao, Y | 1 |
| Shen, ML | 1 |
| Zhai, SK | 1 |
| Yu, WJ | 1 |
| Cattaneo, MG | 2 |
| Palazzi, E | 1 |
| Bondiolotti, G | 1 |
| Vicentini, LM | 2 |
| Favoni, RE | 1 |
| Ravera, F | 1 |
| Pirani, P | 1 |
| Ardizzoni, A | 2 |
| Noonan, D | 1 |
| de Cupis, A | 1 |
| Matturri, L | 1 |
| Lavezzi, AM | 1 |
| Grignani, F | 1 |
| Salomoni, G | 1 |
| Roviaro, GC | 1 |
| Fay, MJ | 1 |
| Friedmann, AS | 1 |
| Yu, XM | 1 |
| North, WG | 1 |
| Kang, YJ | 1 |
| Yano, H | 1 |
| Yoshizawa, Y | 1 |
| Satoh, T | 1 |
| Ohtsuka, M | 1 |
| Murayama, J | 1 |
| Homma, T | 1 |
| Hasegawa, S | 1 |
| Ohsaki, Y | 1 |
| Yang, HK | 1 |
| Le, PT | 1 |
| Jensen, RT | 1 |
| Johnson, BE | 1 |
| Mórocz, IA | 1 |
| Lauber, B | 1 |
| Schmitter, D | 1 |
| Stahel, RA | 1 |
| Hirst, SJ | 1 |
| Barnes, PJ | 1 |
| Twort, CH | 1 |
| Shields, AF | 2 |
| Mankoff, D | 1 |
| Graham, MM | 2 |
| Zheng, M | 2 |
| Kozawa, SM | 2 |
| Link, JM | 2 |
| Krohn, KA | 2 |
| Dearing, MP | 1 |
| Englee-Miller, MJ | 1 |
| Kratzke, RA | 1 |
| Kramer, BS | 1 |
| Chu, E | 1 |
| Weinstein, J | 1 |
| Anderson, M | 1 |
| Venzon, D | 1 |
| Mulshine, JL | 1 |
| Gazdar, AF | 1 |
| Yen, WC | 1 |
| Wientjes, MG | 1 |
| Au, JL | 1 |
| Maruno, K | 1 |
| Said, SI | 1 |
| Fesce, R | 1 |
| Cheong, N | 1 |
| Iliakis, G | 1 |
| Haberkorn, U | 1 |
| Oberdorfer, F | 1 |
| Klenner, T | 1 |
| Strauss, LG | 1 |
| Stöhr, M | 1 |
| Wallich, R | 1 |
| Altmann, A | 1 |
| Kaick, GV | 1 |
| Bonfil, RD | 1 |
| Bustuoabad, OD | 1 |
| Binda, MM | 1 |
| Codignola, A | 1 |
| Missale, C | 1 |
| Spano, P | 1 |
| Clementi, F | 1 |
| Sher, E | 1 |
| Güzey, M | 1 |
| Sattler, C | 1 |
| DeLuca, HF | 1 |
| Bihl, M | 1 |
| Tamm, M | 1 |
| Nauck, M | 1 |
| Wieland, H | 1 |
| Perruchoud, AP | 1 |
| Roth, M | 1 |
| Mankoff, DA | 1 |
| Eary, JF | 1 |
| Lewellen, B | 1 |
| Lewellen, TK | 1 |
| Shafer, SH | 1 |
| Phelps, SH | 1 |
| Williams, CL | 1 |
| Lokshin, A | 1 |
| Peng, X | 1 |
| Campbell, PG | 1 |
| Barsouk, A | 1 |
| Levitt, ML | 1 |
| Franken, NA | 1 |
| Ruurs, P | 1 |
| Ludwików, G | 1 |
| van Bree, C | 1 |
| Kipp, JB | 1 |
| Darroudi, F | 1 |
| Barendsen, GW | 1 |
| Kubasova, T | 1 |
| Petcu, I | 1 |
| Pfüller, U | 1 |
| Köteles, GJ | 1 |
| Smith, PG | 1 |
| Marshman, E | 1 |
| Calvert, AH | 1 |
| Chakraborty, AK | 1 |
| Sodi, S | 1 |
| Rachkovsky, M | 1 |
| Kolesnikova, N | 1 |
| Platt, JT | 1 |
| Bolognia, JL | 1 |
| Pawelek, JM | 1 |
| Lamb, JR | 1 |
| Goehle, S | 1 |
| Ludlow, C | 1 |
| Simon, JA | 1 |
| Boehle, AS | 1 |
| Kurdow, R | 1 |
| Schulze, M | 1 |
| Kliche, U | 1 |
| Sipos, B | 1 |
| Soondrum, K | 1 |
| Ebrahimnejad, A | 1 |
| Dohrmann, P | 1 |
| Kalthoff, H | 1 |
| Henne-Bruns, D | 1 |
| Neumaier, M | 1 |
| Weinfeld, M | 1 |
| Xing, JZ | 1 |
| Lee, J | 1 |
| Leadon, SA | 1 |
| Le, XC | 1 |
| Cohen, IR | 1 |
| Feldman, M | 1 |
| De Gast, GC | 1 |
| Platts-Mills, TA | 1 |
| Hainau, B | 1 |
| Dombernowsky, P | 1 |
| Hansen, HH | 2 |
| Borgeskov, S | 1 |
| Armuth, V | 1 |
| Bertino, JR | 1 |
| Ettinger, DS | 1 |
| Karp, JE | 1 |
| Abeloff, MD | 1 |
| Burke, PJ | 1 |
| Braine, HG | 1 |
| de Munter, HK | 1 |
| den Engelse, L | 1 |
| Emmelot, P | 1 |
| Lee, SS | 1 |
| Giovanella, BC | 1 |
| Stehlin, JS | 1 |
| Brunn, JC | 1 |
| Jerrells, TR | 1 |
| Dean, JH | 1 |
| Richardson, G | 1 |
| Cannon, GB | 1 |
| Herberman, RB | 1 |
| Howell, SB | 1 |
| Jenkins, RS | 1 |
| Streifel, J | 1 |
| Theiss, JC | 1 |
| Shimkin, MB | 2 |
| Vilarem, MJ | 1 |
| Jouanneau, J | 1 |
| Le François, D | 1 |
| Bourrillon, R | 1 |
| Houghton, PJ | 2 |
| Taylor, DM | 1 |
| Straus, SE | 1 |
| Battiste, L | 1 |
| Krezoski, S | 1 |
| Roth, JA | 1 |
| Grimm, EA | 1 |
| Morton, DL | 1 |
| Simpson-Herren, L | 3 |
| Holmquist, JP | 2 |
| Frei, E | 1 |
| Jaffe, N | 1 |
| Tattersall, MH | 1 |
| Pitman, S | 1 |
| Parker, L | 1 |
| Munson, AE | 1 |
| Harris, LS | 1 |
| Friedman, MA | 1 |
| Dewey, WL | 1 |
| Carchman, RA | 1 |
| Watson, JV | 1 |
| Bleehen, NM | 1 |
| Rowles, PM | 1 |
| Kaufmann, M | 2 |
| Mattern, J | 3 |
| Wayss, K | 2 |
| Volm, M | 3 |
| Krutova, TV | 2 |
| Korman, DB | 2 |
| Aksiutina, MS | 1 |
| Liashchenko, VI | 1 |
| Lipchina, LP | 1 |
| Leanderson, P | 1 |
| Tagesson, C | 1 |
| Marini, AM | 1 |
| Fridman, R | 1 |
| Kanemoto, T | 1 |
| Martin, GR | 1 |
| Guo, Y | 1 |
| Passaniti, A | 1 |
| Samsel, B | 1 |
| Iwata, R | 1 |
| Tomura, M | 1 |
| Tada, M | 1 |
| Itoh, J | 1 |
| Kameyama, M | 1 |
| Ido, T | 1 |
| Sheu, JR | 1 |
| Lin, CH | 1 |
| Chung, JL | 1 |
| Teng, CM | 1 |
| Huang, TF | 1 |
| Pogány, G | 1 |
| Cserháti, T | 1 |
| Oláh, J | 1 |
| Valkó, K | 1 |
| Kostenuik, PJ | 1 |
| Singh, G | 1 |
| Suyama, KL | 1 |
| Orr, FW | 1 |
| Stoĭka, RS | 2 |
| Sushel'nitskiĭ, SI | 1 |
| Garas'ko, SI | 1 |
| Shafranskaia, GI | 1 |
| Kusen', SI | 2 |
| Korchinskiĭ, AG | 1 |
| Macaulay, VM | 1 |
| Smith, IE | 2 |
| Everard, MJ | 2 |
| Teale, JD | 2 |
| Reubi, JC | 1 |
| Millar, JL | 2 |
| Seigneurin, D | 1 |
| Guillaud, P | 1 |
| Shieh, HL | 1 |
| Pezzuto, JM | 1 |
| Cordell, GA | 1 |
| Baibakov, B | 1 |
| Frank, GA | 1 |
| Sergeeva, N | 1 |
| Novikova, I | 1 |
| Youngkin, T | 2 |
| Connors, KM | 2 |
| Hoffman, RM | 2 |
| Margolis, LB | 1 |
| Avichezer, D | 1 |
| Gilboa-Garber, N | 1 |
| Harris, AL | 2 |
| Aherne, GW | 1 |
| Vescio, RA | 1 |
| Bordin, GM | 1 |
| Robb, JA | 1 |
| Umbreit, JN | 1 |
| Alama, A | 1 |
| Costantini, M | 1 |
| Repetto, L | 1 |
| Conte, PF | 1 |
| Serrano, J | 1 |
| Nicolin, A | 1 |
| Barbieri, F | 1 |
| Bruzzi, P | 1 |
| Nagahara, N | 1 |
| Kitamura, H | 1 |
| Inoue, T | 1 |
| Ogawa, T | 1 |
| Ito, T | 1 |
| Kanisawa, M | 1 |
| McGuire, Wl | 1 |
| Meyer, JS | 1 |
| Barlogie, B | 1 |
| Kute, TE | 1 |
| Maasberg, M | 1 |
| Rotsch, M | 1 |
| Jaques, G | 1 |
| Enderle-Schmidt, U | 1 |
| Weehle, R | 1 |
| Havemann, K | 1 |
| McGavran, PD | 1 |
| Butterick, CJ | 1 |
| Brody, AR | 1 |
| Orfanoudakis, G | 1 |
| Zaoui, D | 1 |
| Befort, JJ | 1 |
| Bieth, JG | 1 |
| Macauly, VM | 1 |
| Joshi, GP | 1 |
| Sariban, E | 1 |
| Sitaras, NM | 1 |
| Antoniades, HN | 1 |
| Kufe, DW | 1 |
| Pantazis, P | 1 |
| Hartmann, HR | 1 |
| Bollag, W | 1 |
| Weber, S | 1 |
| Zuckerman, JE | 1 |
| Bostwick, DG | 1 |
| Bensch, KG | 1 |
| Sikic, BI | 1 |
| Raffin, TA | 1 |
| Potapov, YN | 1 |
| Pashkova, VS | 1 |
| Deichman, GI | 1 |
| Vendrov, EL | 1 |
| Viano, I | 1 |
| Silvestro, L | 1 |
| Giaccone, G | 1 |
| Compagnoni, G | 1 |
| Donadio, M | 1 |
| Ferrati, P | 1 |
| Dianzani, C | 1 |
| Genazzani, E | 1 |
| Kwok, TT | 1 |
| Fox, NE | 1 |
| Meyer, WH | 1 |
| Houghton, JA | 1 |
| Merkenschlager, M | 1 |
| Kardamakis, D | 1 |
| Rawle, FC | 1 |
| Spurr, N | 1 |
| Beverley, PC | 1 |
| Fermor, B | 1 |
| Umpleby, HC | 1 |
| Lever, JV | 1 |
| Symes, MO | 1 |
| Williamson, RC | 1 |
| Lelieveld, P | 1 |
| Mulder, JH | 1 |
| Takeo, S | 1 |
| Yasumoto, K | 1 |
| Nagashima, A | 1 |
| Nakahashi, H | 1 |
| Sugimachi, K | 1 |
| Nomoto, K | 1 |
| Tada, T | 1 |
| Kodama, T | 1 |
| Watanabe, S | 1 |
| Sato, Y | 1 |
| Shimosato, Y | 1 |
| Kirkhus, B | 1 |
| Iversen, OH | 1 |
| Kristensen, A | 1 |
| Lindenschmidt, RC | 1 |
| Tryka, AF | 1 |
| Witschi, HP | 1 |
| Schwartz, R | 1 |
| Walk, A | 1 |
| Toomes, H | 1 |
| Schirrmacher, V | 1 |
| Knock, FE | 2 |
| Galt, RM | 2 |
| Oester, YT | 2 |
| Sylvester, R | 2 |
| Sekizuka, H | 1 |
| Haki, K | 1 |
| Iwasa, H | 1 |
| Murakami, T | 1 |
| Wüst, GP | 1 |
| Krüsmann, WF | 1 |
| Slanina, J | 1 |
| Hennekeuser, HH | 1 |
| Wahren, C | 1 |
| Scholz, R | 1 |
| Vorwerck, H | 1 |
| Watkins, E | 2 |
| Ogata, Y | 1 |
| Anderson, LL | 1 |
| Waters, MF | 1 |
| Han, T | 1 |
| Takita, H | 1 |
| Konen, TG | 1 |
| Smith, GS | 2 |
| Walford, RL | 2 |
| Livingston, RB | 1 |
| Ambus, U | 2 |
| George, SL | 1 |
| Freireich, EJ | 1 |
| Hart, JS | 1 |
| Weiss, RA | 1 |
| Veselý, P | 1 |
| Sindelarova, J | 1 |
| Yuhas, JM | 1 |
| Toya, RE | 1 |
| Pazmiño, NH | 1 |
| Muggia, FM | 4 |
| Krezoski, SK | 1 |
| Mavligit, GM | 1 |
| Gutterman, JU | 1 |
| Hersh, EM | 1 |
| McBride, CM | 1 |
| Mathies, M | 1 |
| Lipps, L | 1 |
| Zeidman, I | 1 |
| Jenkins, VK | 1 |
| Olson, MH | 1 |
| Ellis, HN | 1 |
| Grdina, DJ | 1 |
| Milas, L | 1 |
| Mason, KA | 1 |
| Withers, HR | 1 |
| Goldman, LI | 1 |
| Flaxman, BA | 1 |
| Wernick, G | 1 |
| Zabriskie, JB | 1 |
| Wheeler, GP | 1 |
| Alexander, JA | 1 |
| Sanford, AH | 1 |
| Creasey, WA | 1 |
| Capizzi, RL | 1 |
| DeConti, RC | 1 |
| DeVita, VT | 1 |
| Kauffman, SL | 2 |
| Wolberg, WH | 1 |
| Mizuno, NS | 1 |
| Humphrey, EW | 1 |
| Terz, JJ | 1 |
| Curutchet, HP | 1 |
| Lawrence, W | 1 |
| Sutherland, RM | 1 |
| Inch, WR | 1 |
| McCredie, JA | 1 |
| Owen, LN | 1 |
| Steel, GG | 2 |
| Lamerton, LF | 1 |
| Teeter, A | 1 |
| Nielsen, B | 1 |
| Lloyd, HH | 1 |
| Thomas, JW | 1 |
| Lewis, HS | 1 |
| Yuen, A | 1 |
| Divertie, MB | 1 |
| Shorter, RG | 1 |
| Titus, JL | 1 |
| Sasaki, T | 1 |
| McDonough, M | 1 |
| Baserga, R | 1 |
| Thatcher, D | 1 |
| Wieder, R | 1 |
| Malaise, EP | 1 |
| Boeryd, B | 1 |
| Lundin, PM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Substudy of Efficacy, Safety and Toxicology of Electronic Nicotine Delivery Systems as an Aid for Smoking Cessation (ESTxENDS Trial)- the Oxidative Stress Measured in EBC Substudy of ESTxENDS[NCT03612453] | 155 participants (Actual) | Interventional | 2019-04-03 | Completed | |||
| Substudy of Efficacy, Safety and Toxicology of Electronic Nicotine Delivery Systems as an Aid for Smoking Cessation (ESTxENDS Trial)- the Oxidative Stress Substudy of ESTxENDS[NCT03612375] | 1,246 participants (Actual) | Interventional | 2018-07-16 | Completed | |||
| Could Positon Emission Tomography With Radiolabelled 3'-Deoxy-3'-(18)F-Fluoro-L-Thymidine be a Theranostic Tool During Erlotinib Treatment in Non-small Cell Lung Cancer Patients ?[NCT02069418] | Phase 2 | 80 participants (Anticipated) | Interventional | 2014-02-28 | Active, not recruiting | ||
| A Pilot Study of 18F FLT PET/CT in Evaluating Early Response to Anti-Proliferative Therapies in Non Small Cell Lung Cancer and Thymic Tumors[NCT01610544] | Phase 2 | 0 participants (Actual) | Interventional | 2012-05-10 | Withdrawn | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for thymidine and Cancer of Lung
| Article | Year |
|---|---|
Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Ascorbic Acid; Biomarkers; Carotenoids; Dehydroascorbic Acid | 2013 |
Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Ascorbic Acid; Biomarkers; Carotenoids; Dehydroascorbic Acid | 2013 |
Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Ascorbic Acid; Biomarkers; Carotenoids; Dehydroascorbic Acid | 2013 |
Lung cancer biomarkers for the assessment of modified risk tobacco products: an oxidative stress perspective.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aldehydes; Ascorbic Acid; Biomarkers; Carotenoids; Dehydroascorbic Acid | 2013 |
On the origin of G --> T transversions in lung cancer.
Topics: Databases, Genetic; DNA Damage; DNA Repair; DNA, Neoplasm; Gene Frequency; Guanine; Humans; Lung Neo | 2003 |
Small cell anaplastic carcinoma of the lung. A review of growth characteristics and implications for chemotherapy.
Topics: Autoradiography; Carcinoma, Small Cell; Cell Division; Humans; Lung Neoplasms; Thymidine; Time Facto | 1982 |
[Ki-67 antigen, a cell cycle and tumor growth marker].
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Flow Cytometry; G1 Phase; Human | 1991 |
The growth characteristics of lung cancer and its application to treatment design.
Topics: Cell Division; Cell Movement; Humans; Lung Neoplasms; Mitosis; Neoplasm Metastasis; Prognosis; Radio | 1974 |
6 trials available for thymidine and Cancer of Lung
| Article | Year |
|---|---|
[Analysis of the prophylactic effect of nucleosides against reactivation of HBV in HBsAg-positive patients with non-hepatic tumors after chemotherapy].
Topics: Adult; Antineoplastic Agents; Antiviral Agents; Breast Neoplasms; Female; Follow-Up Studies; Guanine | 2010 |
Changes in 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine positron emission tomography imaging in patients with non-small cell lung cancer treated with erlotinib.
Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease Progression; Erlotinib Hydrochl | 2011 |
4'-[Methyl-11C]-thiothymidine PET/CT for proliferation imaging in non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Biological Transport; Carbon Radioisotopes; Carcinoma, Non-Small-Cell Lung; | 2012 |
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small- | 2007 |
Intermittent high-dose cyclophosphamide chemotherapy for small cell carcinoma of the lung.
Topics: Aged; Autoradiography; Bone Marrow; Bone Marrow Cells; Carcinoma; Clinical Trials as Topic; Cyclopho | 1978 |
Clinical and biochemical studies of high-dose intermittent therapy of solid tumors with hydroxyurea (NSC-32065).
Topics: Adult; Aged; Blood Urea Nitrogen; Chondrosarcoma; Clinical Trials as Topic; Depression, Chemical; DN | 1970 |
178 other studies available for thymidine and Cancer of Lung
| Article | Year |
|---|---|
Synthesis and tumor uptake of 5-82Br- and 5-131I-labeled 5-halo-1-(2-fluoro-2-deoxy-beta-D-ribofuranosyl)uracils.
Topics: Animals; Biological Transport; Bromine Radioisotopes; Chemical Phenomena; Chemistry; DNA; Female; Fl | 1989 |
Synthesis and tumor uptake of 5-halo-1-(2'-fluoro-2'-deoxy-beta-D-ribofuranosyl)[2-14C]uracils.
Topics: Animals; Antimetabolites, Antineoplastic; Biological Transport; Carcinoma; Carrier Proteins; Erythro | 1987 |
Circular RNA circ_0007841 participates in progression of nonsmall cell lung cancer via miR-199a-5p/SphK2 axis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Mice; MicroRNAs | 2022 |
Exploring New Potential Anticancer Activities of the G-Quadruplexes Formed by [(GTG
Topics: Amino Acid Substitution; Antineoplastic Agents; Aptamers, Nucleotide; Cell Line, Tumor; Cell Movemen | 2021 |
Dexamethasone pretreatment impairs the thymidylate synthase inhibition mediated flare in thymidine salvage pathway activity in non-small cell lung cancer.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Dexamethasone; Enzyme Inhibitors; Humans; Lung Neoplasms | 2018 |
Thymidine phosphorylase influences [(18)F]fluorothymidine uptake in cancer cells and patients with non-small cell lung cancer.
Topics: Adult; Aged; Biological Transport; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dideoxynucleosi | 2014 |
Glutaminase 1 inhibition reduces thymidine synthesis in NSCLC.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Glutaminase; Humans; Lung Neoplasms; Thymidine | 2016 |
Early detection of pemetrexed-induced inhibition of thymidylate synthase in non-small cell lung cancer with FLT-PET imaging.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease Models, An | 2017 |
[18F]Fluorothymidine positron emission tomography before and 7 days after gefitinib treatment predicts response in patients with advanced adenocarcinoma of the lung.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Female; Fluorine Radioisotope | 2008 |
Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity.
Topics: Animals; Antimetabolites, Antineoplastic; Cell Proliferation; Dipyridamole; Drug Synergism; Female; | 2009 |
Characteristics of PBMC obtained from leukapheresis products and tumor biopsies of patients with non-small cell lung cancer.
Topics: Biopsy; Carcinoma, Non-Small-Cell Lung; Cytokines; Dendritic Cells; Humans; Immune System; Immunothe | 2009 |
Arsenic trioxide modulates DNA synthesis and apoptosis in lung carcinoma cells.
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Caspase 3; Cell Cycle; Cell Line, Tumor; DNA Replication; H | 2010 |
ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.
Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Surviva | 2011 |
A pilot study for the early assessment of the effects of BMS-754807 plus gefitinib in an H292 tumor model by [(18)F]fluorothymidine-positron emission tomography.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell P | 2013 |
Arachidonic acid metabolism in growth control of A549 human lung adenocarcinoma cells.
Topics: Adenocarcinoma; Arachidonic Acids; Carbon Radioisotopes; Cell Division; Cyclooxygenase Inhibitors; D | 2002 |
Cultures of surgical material from lung cancers. A kinetic approach.
Topics: Cell Division; Humans; Lung Neoplasms; Thymidine; Tumor Cells, Cultured | 2003 |
Stereoselective and improved syntheses and anticancer testing of 3'-O-silatranylthymidines.
Topics: Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; C | 2002 |
Recombinant adenoviruses expressing dominant negative insulin-like growth factor-I receptor demonstrate antitumor effects on lung cancer.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Adenoviridae; Animals; Carcinoma, Large Cell; Cell Division; Co | 2003 |
Comparison of multiple DNA adduct types in tumor adjacent human lung tissue: effect of cigarette smoking.
Topics: Aged; Deoxyadenosines; Deoxycytidine; DNA Adducts; DNA Damage; Female; Humans; Hydrocarbons; Lung Ne | 2002 |
Down-regulation of SKP2 induces apoptosis in lung-cancer cells.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Caspase 3; Caspases; Cell Cycle; C | 2003 |
X-RAY INHIBITION OF URETHAN-STIMULATED PROLIFERATION OF LUNG CELLS OF THE MOUSE AS ESTIMATED BY INCORPORATION OF TRITIATED THYMIDINE.
Topics: Animals; Carcinogens; Lung Neoplasms; Metabolism; Mice; Neoplasms; Neoplasms, Experimental; Radiatio | 1963 |
INFLUENCE OF MUTAGENS ON THE INITIATION OF SKIN CARCINOGENESIS.
Topics: 2-Aminopurine; Acridines; Adenine; Carcinogenesis; Carcinogens; Idoxuridine; Lung Neoplasms; Mice; M | 1964 |
Bombesin/gastrin-releasing peptide receptor: a potential target for antibody-mediated therapy of small cell lung cancer.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Body Weight; Bombesin; Carcinoma, Non-Small-Cell | 2003 |
Thymidine rescue: an antidote for pemetrexed-related toxicity in the setting of acute renal failure.
Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Cisplatin; Drug Therapy, Combination; Humans; | 2003 |
Nkx2.1 transcription factor in lung cells and a transforming growth factor-beta1 heterozygous mouse model of lung carcinogenesis.
Topics: Animals; Blotting, Northern; Cell Transformation, Neoplastic; Disease Models, Animal; Gene Expressio | 2004 |
The development of VIP-ellipticine conjugates.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Drug Design; Ellipticines; | 2004 |
Increased Fas expression reduces the metastatic potential of human osteosarcoma cells.
Topics: Animals; Apoptosis; Bone Neoplasms; fas Receptor; Gene Expression Regulation, Neoplastic; Humans; Lu | 2004 |
Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their nucleoside conjugates.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Cell Survival; Chlorocebus aethiops; Cricet | 2005 |
Interleukin-2 receptors in patients with lung carcinoma metastasis undergoing treatment with disodium-clodronate. Preliminary research.
Topics: Bone Density Conservation Agents; Clodronic Acid; DNA, Neoplasm; Enzyme-Linked Immunosorbent Assay; | 1989 |
The effect of N-acetylcysteine in combination with vitamin C on the activity of ornithine decarboxylase of lung carcinoma cells--In vitro.
Topics: Acetylcysteine; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA, Neoplasm; D | 2006 |
Antimetastatic activity of Sulforaphane.
Topics: Animals; Antineoplastic Agents; Biomarkers, Tumor; Brassica; Cell Line; Cell Proliferation; Collagen | 2006 |
D2 dopamine receptor-mediated antiproliferation in a small cell lung cancer cell line, NCI-H69.
Topics: Bromocriptine; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; Dop | 2007 |
A simple quantitative assay for the activity of thymidine kinase 1 in solid tumors.
Topics: Carcinoma, Non-Small-Cell Lung; Cells, Cultured; Humans; Lung Neoplasms; Neoplasm Proteins; Radiopha | 2007 |
Actual growth rate and tumour cell proliferation in human pulmonary neoplasms.
Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Divis | 1984 |
The response of tumour cells to radiation and cytotoxic drugs--a comparison of clonogenic and isotope uptake assays.
Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Survival; Colony-Forming Units Assay; Do | 1984 |
Labeling indices of human lung cancer. Correlation with histologic type and survival.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Female; Humans; Interp | 1983 |
The cytokinetic and cytotoxic effects of ICRF-159 and ICRF-187 in vitro and ICRF-187 in human bone marrow in vivo.
Topics: Antineoplastic Agents; Bone Marrow Cells; Bone Neoplasms; Burkitt Lymphoma; Cell Cycle; Cell Divisio | 1983 |
[Cell cycles of cancer cells and chemotherapy--flow cytometric observation of the effects of chemotherapeutic agents on cell kinetics of cultured human lung cancer cells].
Topics: Adenoma; Carcinoma; Cells, Cultured; DNA, Neoplasm; Doxorubicin; Drug Evaluation, Preclinical; Flow | 1983 |
Mechanism of the antimetastatic action of N-diazoacetylglycinamide in mice bearing Lewis lung carcinoma.
Topics: Animals; Azo Compounds; Dose-Response Relationship, Drug; Glycine; Lung Neoplasms; Mice; Mice, Inbre | 1980 |
In vitro thymidine labelling of human pulmonary neoplasms.
Topics: Cell Division; Humans; Isotope Labeling; Lung Neoplasms; Mitotic Index; Thymidine; Tritium | 1983 |
In vitro cytotoxicity of VP 16 on primary tumor and metastasis of Lewis lung carcinoma.
Topics: Animals; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Etoposide; Lung Neoplasms | 1982 |
Direct antitumor effect of high-molecular-weight levan on Lewis lung carcinoma cells in mice.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Survival; Cells, Cultured; DNA, Neoplasm; Fructans; | 1980 |
Isolation of tumor cells from patients with osteosarcoma and analysis of their sensitivity to methotrexate.
Topics: Cell Separation; Cells, Cultured; Deoxyuridine; DNA; Drug Resistance; Humans; Hypoxanthines; Lung Ne | 1981 |
Rates of incorporation of radioactive molecules during the cell cycle.
Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA; In Vitro Techniques; Interphase; Lung Neoplasms; Ly | 1981 |
Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplas | 1981 |
Effect of high dose diethylstilbestrol and ICRF-159 on the growth and metastases of the R3327 MAT-LyLu prostate-derived tumor.
Topics: Animals; Diethylstilbestrol; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasms, Experimental; Pi | 1981 |
[Comparison of 3H-TdR incorporation and morphologic method in lymphocyte transformation test for immunity in patients suffering from lung cancers (author's transl)].
Topics: Adult; Age Factors; Aged; Female; Humans; Lung Neoplasms; Lymphocyte Activation; Male; Middle Aged; | 1981 |
5-HT1D receptor type is involved in stimulation of cell proliferation by serotonin in human small cell lung carcinoma.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Carcinoma, Small Cell; Cell Division; Colforsin; Hum | 1994 |
Suramin interferes with auto/paracrine insulin-like growth factor I-controlled proliferative loop on human lung cancer cell lines.
Topics: Adenocarcinoma; Binding, Competitive; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell | 1994 |
The prognostic value of cell proliferation in non-small cell lung cancer assessed with tritiated thymidine and anti-PCNA antibodies.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Survival; Humans; Lung Neoplasms; Prognosis; Pro | 1994 |
Vasopressin and vasopressin-receptor immunoreactivity in small-cell lung carcinoma (SCCL) cell lines: disruption in the activation cascade of V1a-receptors in variant SCCL.
Topics: Calcimycin; Calcium; Carcinoma, Small Cell; Cytosol; Humans; Lung Neoplasms; Receptors, Vasopressin; | 1994 |
Buthionine sulfoximine spares intracellular glutamate: a possible mechanism for cell growth stimulation.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Division; Cell L | 1993 |
[Pathogenesis of development of lung cancer in idiopathic interstitial pneumonia--growth factors in bronchoalveolar lavage fluid].
Topics: Aged; Aged, 80 and over; Animals; Bronchoalveolar Lavage Fluid; Growth Substances; Humans; Lung Neop | 1993 |
Human small cell lung cancer cell lines express functional atrial natriuretic peptide receptors.
Topics: Atrial Natriuretic Factor; Base Sequence; Blotting, Southern; Carcinoma, Small Cell; Cell Division; | 1993 |
In vitro effect of suramin on lung tumour cells.
Topics: DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Leucine; | 1993 |
PDGF isoform-induced proliferation and receptor expression in human cultured airway smooth muscle cells.
Topics: Adult; Aged; Becaplermin; Bronchi; Cell Division; Cells, Cultured; Female; Gene Expression; Humans; | 1996 |
Analysis of 2-carbon-11-thymidine blood metabolites in PET imaging.
Topics: Carbon Dioxide; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Humans; Lung Neoplasms; | 1996 |
Dipyridamole mediated enhanced antiproliferative activity of 10-ethyl-10-deazaaminopterin (10-EDAM) against human lung cancer cell lines.
Topics: Aminopterin; Biological Transport; Cell Division; Depression, Chemical; Dipyridamole; Dose-Response | 1996 |
Differential effect of taxol in rat primary and metastatic prostate tumors: site-dependent pharmacodynamics.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; ATP Binding Cassette Transporter, Subfamily B | 1996 |
VIP inhibits the proliferation of small-cell and nonsmall-cell lung carcinoma.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Count; Cell Division; Cell Line | 1996 |
Evidence for receptor subtype cross-talk in the mitogenic action of serotonin on human small-cell lung carcinoma cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Sma | 1996 |
In vitro rejoining of double strand breaks induced in cellular DNA by bleomycin and restriction endonucleases.
Topics: Adenocarcinoma; Bleomycin; Deoxyribonuclease BamHI; Deoxyribonucleases, Type II Site-Specific; DNA D | 1997 |
Metabolic and transcriptional changes in osteosarcoma cells treated with chemotherapeutic drugs.
Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Cisplatin; Deoxyglucose; Flow Cytometry; Fluorodeoxy | 1994 |
Antiangiogenesis and apoptosis as mediators of concomitant tumor resistance induced by Calu-6, a human lung carcinoma cell line, in nude mice.
Topics: Animals; Apoptosis; Cell Division; Cell Line; DNA, Neoplasm; Humans; Immunity, Innate; Lung Neoplasm | 1998 |
Downregulation of nicotinic acetylcholine receptors by nerve growth factor in human small cell lung carcinoma cell lines.
Topics: Carcinoma, Small Cell; Cell Division; Down-Regulation; Humans; Lung Neoplasms; Nerve Growth Factors; | 1998 |
Combinational effects of vitamin D3 and retinoic acid (all trans and 9 cis) on proliferation, differentiation, and programmed cell death in two small cell lung carcinoma cell lines.
Topics: Alitretinoin; Apoptosis; Carcinoma, Small Cell; Cell Differentiation; Cell Division; Cholecalciferol | 1998 |
Proliferation of human non-small-cell lung cancer cell lines: role of interleukin-6.
Topics: Antibodies; Antisense Elements (Genetics); Blood Proteins; Carcinoma, Non-Small-Cell Lung; Cell Divi | 1998 |
Carbon-11-thymidine and FDG to measure therapy response.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carbon Radioisotopes; Carcinoma, Small Cell; Fluorin | 1998 |
Reduced DNA synthesis and cell viability in small cell lung carcinoma by treatment with cyclic AMP phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Caffeine; Calcium; Carcinoma, Small Cell; Cell Survival; Cyclic | 1998 |
Mechanisms of growth stimulation by suramin in non-small-cell lung cancer cell lines.
Topics: Antineoplastic Agents; Carcinoma, Adenosquamous; Carcinoma, Non-Small-Cell Lung; Cell Division; Dime | 1999 |
Correlation between cell reproductive death and chromosome aberrations assessed by FISH for low and high doses of radiation and sensitization by iodo-deoxyuridine in human SW-1573 cells.
Topics: Carcinoma, Squamous Cell; Cell Death; Cell Division; Cell Survival; Chromosome Aberrations; Chromoso | 1999 |
Effects of mistletoe lectin I and ionizing radiation on the glucose and thymidine uptake in tumour cells in vitro.
Topics: Combined Modality Therapy; Glucose; Humans; Lectins; Lung Neoplasms; Mistletoe; Plant Lectins; Plant | 1999 |
Prevention of thymidine and hypoxanthine rescue from MTA (LY231514) growth inhibition by dipyridamole in human lung cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Carcinoma, Non-Small-Cell Lung; Cell Division; Dipyridamole; Enzyme | 1999 |
A spontaneous murine melanoma lung metastasis comprised of host x tumor hybrids.
Topics: Aminopterin; Animals; Anti-Bacterial Agents; Antigens, CD; Antineoplastic Combined Chemotherapy Prot | 2000 |
Thymidine incorporation is highly predictive of colony formation and can be used for high-throughput screening.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Survival; Chickens; CHO Cells; Colonic Neoplasms | 2001 |
Human endostatin inhibits growth of human non-small-cell lung cancer in a murine xenotransplant model.
Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; Cell Movement; Cell Su | 2001 |
Immunofluorescence detection of radiation-induced DNA base damage.
Topics: Adenocarcinoma; DNA; Electrophoresis, Capillary; Fluorescent Antibody Technique; Humans; Hydrogen-Io | 2002 |
Cellular interactions controlling the immune reactivity of T-lymphocytes.
Topics: Animals; B-Lymphocytes; Binding Sites, Antibody; Bone Marrow Cells; Cell Differentiation; Concanaval | 1975 |
Functional studies on T cells in adult human bone marrow.
Topics: Adult; Aged; Bone Marrow Cells; Cell Count; Cell Division; Cytotoxicity, Immunologic; Humans; Immuno | 1979 |
Cell proliferation and histologic classification of bronchogenic carcinoma.
Topics: Adenocarcinoma; Adult; Aged; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cel | 1977 |
Tritiated thymidine as a broad spectrum initiator in transplacental two-stage carcinogenesis, with phorbol as promoter.
Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma; Male | 1979 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru | 1977 |
Studies on lung tumours. IV. Correlation between [3H]thymidine labelling of lung and liver cells and tumour formation in GRS/A and C3Hf/A male mice following administration of dimethylnitrosamine.
Topics: Animals; Cell Survival; Dimethylnitrosamine; Liver; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred C | 1979 |
Regression of human tumors established in nude mice after continuous infusion of thymidine.
Topics: Animals; Breast Neoplasms; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Melanoma; Mi | 1979 |
Increased monocyte-mediated cytostasis of lymphoid cell lines in breast and lung cancer patients.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; BCG Vaccine; Breast Neoplasms; Cell Adhesion; Cell Di | 1979 |
Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Humans; Lung Neopl | 1979 |
Inhibiting effect of caffeine on spontaneous and urethan-induced lung tumors in strain A mice.
Topics: Adenoma; Animals; Caffeine; DNA; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experi | 1978 |
Differential effects of lectins on the in vitro growth of normal mouse lung cells and low- and high-cancer-derived cell lines.
Topics: Animals; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; Concanavalin A; L | 1978 |
Fractional incorporation of [3H]thymidine and DNA specific activity as assays of inhibition of tumour growth.
Topics: Animals; Cyclophosphamide; DNA, Neoplasm; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neoplasm Transpl | 1977 |
The uptake, excretion, and radiation hazards of tritiated thymidine in humans.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; DNA, Neoplasm; Half-Life; Head and Neck | 1977 |
A rapid assay for stimulation of human lymphocytes by tumor-associated antigens.
Topics: Antigens, Neoplasm; Carcinoma; Female; Hemagglutination Tests; Hemocyanins; Humans; Leucine; Lung; L | 1976 |
Effects of surgery on the cell kinetics of residual tumor.
Topics: Animals; Cell Division; Cell Survival; Kinetics; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inb | 1976 |
New approaches to cancer chemotherapy with methotrexate.
Topics: Adult; Animals; Biological Transport; Bone Marrow; Creatinine; DNA, Neoplasm; Doxorubicin; Drug Ther | 1975 |
Antineoplastic activity of cannabinoids.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Bone Marrow; Bone Marrow Cells; Cannabidiol; C | 1975 |
Changes in cell proliferation kinetics occurring during the life history of monolayer cultures of a mouse tumour cell line.
Topics: Animals; Autoradiography; Cell Count; Cell Division; Cell Line; Culture Media; DNA, Neoplasm; Kineti | 1975 |
[The effect of cyclophosphamide on tumors in the sensitivity-test (author's transl)].
Topics: Adenocarcinoma; Alkylation; Animals; Breast Neoplasms; Carcinoma 256, Walker; Cell Count; Cell Divis | 1975 |
[Testing of the resistance of human tumours in the short-term test (author's transl)].
Topics: Antibiotics, Antineoplastic; Dactinomycin; Daunorubicin; Doxorubicin; Drug Resistance; Female; Human | 1975 |
[The relationship between the doubling time of human lung tumor volume and the labelling index].
Topics: Carcinoma, Squamous Cell; DNA, Neoplasm; Hamartoma; Humans; Lung Neoplasms; Thymidine | 1976 |
Cigarette smoke-induced DNA damage in cultured human lung cells: role of hydroxyl radicals and endonuclease activation.
Topics: Cell Line; DNA Damage; DNA, Neoplasm; DNA, Single-Stranded; Free Radicals; Humans; Hydrogen Peroxide | 1992 |
The neurotoxin 1-methyl-4-phenylpyridinium: a selective cytostatic agent in small-cell lung cancer cell lines with neuroendocrine properties.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Antineoplastic Agents; Carcinoma, Small Cell; DNA, Neoplasm; G | 1992 |
Relationship of inherent resistance to doxorubicin, proliferative activity and expression of P-glycoprotein 170, and glutathione S-transferase-pi in human lung tumors.
Topics: Adult; Aged; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biopsy; Carcinoma, Non-Small-C | 1992 |
Tumor diagnosis by PET: potential of seven tracers examined in five experimental tumors including an artificial metastasis model.
Topics: Animals; Carbon Radioisotopes; Deoxyglucose; Diagnosis, Differential; Disease Models, Animal; Floxur | 1992 |
Triflavin, an Arg-Gly-Asp-containing antiplatelet peptide inhibits cell-substratum adhesion and melanoma cell-induced lung colonization.
Topics: Animals; Antineoplastic Agents; Cell Adhesion; Cell Survival; Crotalid Venoms; DNA Replication; Kine | 1992 |
Relationships between the chromatographic retention data and the effects of nucleoside derivatives in highly metastatic 3LL cells.
Topics: Animals; Chromatography, Thin Layer; DNA, Neoplasm; Lung Neoplasms; Neoplasm Metastasis; Nucleosides | 1992 |
A quantitative model for spontaneous bone metastasis: evidence for a mitogenic effect of bone on Walker 256 cancer cells.
Topics: Animals; Body Burden; Bone and Bones; Bone Neoplasms; Carcinoma 256, Walker; Cell Division; Female; | 1992 |
[The autocrine regulation of the proliferation of cell line A-549 under conditions facilitating the acidification of the culture medium].
Topics: Adenocarcinoma; Cell Division; Cell Line; Culture Media, Conditioned; Culture Media, Serum-Free; DNA | 1992 |
[Heat shock modulates the ability of A-549 cell line from human lung adenocarcinoma to regulate the intensity of DNA and protein biosynthesis by an autocrine mechanism].
Topics: Adenocarcinoma; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Heat-Shock Proteins; Hormones; H | 1992 |
Experimental and clinical studies with somatostatin analogue octreotide in small cell lung cancer.
Topics: Animals; Carcinoma, Small Cell; Cell Line; Cell Survival; DNA Replication; Humans; Lung Neoplasms; M | 1991 |
Evaluation of the cytotoxic mechanisms mediated by the broad-spectrum antitumor alkaloid acronycine and selected semisynthetic derivatives.
Topics: Acronine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Cell Nucleus; Cel | 1992 |
In vivo growth patterns of human lung tumors in three-dimensional histoculture.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Cell Division; Cell Transformation, Neoplastic; DNA, Neopl | 1991 |
Antitumoral effects of Pseudomonas aeruginosa lectins on Lewis lung carcinoma cells cultured in vitro without and with murine splenocytes.
Topics: Animals; Antineoplastic Agents; Carcinoma; Cell Survival; Fucose; Gentian Violet; Lectins; Lung Neop | 1991 |
Mechanism of cell death following thymidylate synthase inhibition: 2'-deoxyuridine-5'-triphosphate accumulation, DNA damage, and growth inhibition following exposure to CB3717 and dipyridamole.
Topics: Cell Division; Cell Survival; Deoxyuracil Nucleotides; Dipyridamole; DNA Damage; Drug Synergism; Fol | 1991 |
Cancer biology for individualized therapy: correlation of growth fraction index in native-state histoculture with tumor grade and stage.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Division; Colonic Neoplasms; DNA Replication; Female; Humans; L | 1990 |
Thymidine labelling index as prognostic factor in resected non-small cell lung cancer.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; DNA, Neoplasm; Female; Humans; Lung Neoplasms; Male; Mi | 1990 |
Effect of glycerol on cell kinetics and tumorigenesis in mouse lung following urethan administration.
Topics: Animals; Bronchi; Cell Cycle; Cell Transformation, Neoplastic; DNA; Epithelium; Glycerol; Interphase | 1990 |
Impact of flow cytometry on predicting recurrence and survival in breast cancer patients.
Topics: Analysis of Variance; Aneuploidy; Breast Neoplasms; Bromodeoxyuridine; Carcinoma, Small Cell; Cell C | 1985 |
Androgen receptors, androgen-dependent proliferation, and 5 alpha-reductase activity of small-cell lung cancer cell lines.
Topics: Androgen Antagonists; Androgens; Carcinoma, Small Cell; Cell Division; Cell Line; Centrifugation, De | 1989 |
Tritiated thymidine incorporation and the development of an interstitial lesion in the bronchiolar-alveolar regions of the lungs of normal and complement deficient mice after inhalation of chrysotile asbestos.
Topics: Administration, Inhalation; Animals; Asbestos; Autoradiography; Bronchi; Bronchial Neoplasms; Comple | 1989 |
Cell cycle-specific variation of intracellular plasminogen activator activity in cultured human alveolar epithelial carcinoma and rat hepatoma cells.
Topics: Animals; Carcinoma; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Plasminogen Activators; R | 1989 |
Somatomedin-C/insulin-like growth factor-I is a mitogen for human small cell lung cancer.
Topics: Adenocarcinoma; Carcinoma, Small Cell; DNA; Humans; Insulin-Like Growth Factor I; Lung Neoplasms; Ma | 1988 |
Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines.
Topics: Binding, Competitive; Breast Neoplasms; Carcinoma; Cell Line; Colonic Neoplasms; Epithelium; Female; | 1988 |
A comparison of patient survival and tumour growth kinetics in human bronchogenic carcinoma.
Topics: Adenocarcinoma; Carcinoma, Bronchogenic; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Cell Divis | 1988 |
Modulation of the effects of fluoropyrimidines on toxicity and tumor inhibition in rodents by uridine and thymidine.
Topics: Animals; Dose-Response Relationship, Drug; Female; Floxuridine; Fluorouracil; Leukemia L1210; Lung N | 1986 |
Gastrin releasing peptide is a selective mitogen for small cell lung carcinoma in vitro.
Topics: Carcinoma, Small Cell; Cell Count; Gastrin-Releasing Peptide; Humans; Lung Neoplasms; Microscopy, El | 1985 |
The study of the cytotoxic effect of anticancer drugs on human lung tumors transplanted to mice by use of diffusion chambers.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Dif | 1985 |
Characteristics of in vitro transformed cells essential for their in vivo survival, selection and metastasizing activity.
Topics: Adenoviridae; Animals; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cri | 1986 |
In vitro evaluation of myelotoxicity induced by antineoplastic drugs.
Topics: Antineoplastic Agents; Bone Marrow; Carcinoma, Small Cell; Humans; In Vitro Techniques; Leukocyte Co | 1986 |
Use of a tritiated thymidine suicide technique in the study of the cytotoxic drug response of cells located at different depths within multicellular spheroids.
Topics: Animals; Antineoplastic Agents; Carcinoma, Small Cell; Cell Cycle; Cell Line; Cell Separation; Cell | 1987 |
A comparison of clonogenic and radionuclide uptake assays for determining the radiation response of human small-cell lung cancer xenografts and cell lines.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Line; Cell Survival; Dose-Response Relat | 1987 |
Hypoxanthine:guanine phosphoribosyltransferase activity in primary human osteosarcomas. A rationale for therapy with methotrexate-thymidine rescue?
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Female; Humans; Hypoxanthine; | 1987 |
Rate of incorporation of radiolabelled nucleosides does not necessarily reflect the metabolic state of cells in culture: effects of latent mycoplasma contamination.
Topics: Cell Line; Colonic Neoplasms; Humans; Lung Neoplasms; Mycoplasma Infections; Pyrimidine Nucleosides; | 1988 |
Potentiation of quinazoline antifolate (CB3717) toxicity by dipyridamole in human lung carcinoma, A549, cells.
Topics: Carcinoma; Cell Survival; Dipyridamole; DNA; Drug Synergism; Folic Acid; Folic Acid Antagonists; Hum | 1988 |
Proliferative and metastatic potential of exfoliated colorectal cancer cells.
Topics: Animals; Autoradiography; Cell Division; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Mice; Mi | 1986 |
Three tumor sensitivity tests evaluated with mouse tumors.
Topics: Animals; Antineoplastic Agents; Colony-Forming Units Assay; Disease Models, Animal; Lung Neoplasms; | 1987 |
Role of tumor-associated macrophages in lung cancer.
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Female; Humans; Lung Neoplasms; Lymphatic Metastasis; Macr | 1986 |
Immunohistochemical cell kinetic study of human lung cancer by using monoclonal antibody to bromodeoxyuridine.
Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Division; Histocytochemistry; Humans; In Vi | 1986 |
Carcinogenic doses of methylnitrosourea induce dose response related delay in transit through S and G2 phases in mouse epidermis: a cell kinetic study.
Topics: Adenoma; Animals; Carcinoma; DNA Replication; Flow Cytometry; Interphase; Kinetics; Lung Neoplasms; | 1987 |
Inhibition of mouse lung tumor development by hyperoxia.
Topics: Animals; Body Weight; Cell Division; Dose-Response Relationship, Drug; Free Radicals; Lung; Lung Neo | 1986 |
Assay for the determination of human carcinoma cells in circulating blood.
Topics: Adult; Aged; Carcinoma; Carcinoma, Squamous Cell; Cell Line; Centrifugation, Density Gradient; Colon | 1985 |
Inhibition of DNA polymerases and neoplastic cells by selected SH inhibitors.
Topics: Animals; Antineoplastic Agents; Arsenicals; Benzoates; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Ch | 1972 |
Effect of anticancer chemotherapy on the lymphocyte blastoid transformation.
Topics: Adult; Aged; Animals; Bleomycin; Cyclophosphamide; Fluorouracil; Gastrointestinal Neoplasms; Humans; | 1973 |
[On the question of preclinical selection of cytostatics in the area of treatment of human tumors].
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carcinoma 256, Walker; Cricetinae; Culture Te | 1969 |
[Alteration of PHA stimulation and of cytochemical behaviour of lymphocytes from patients with Hodgkin's disease and bronchogenic carcinoma induced by 60Co radiotherapy (author's transl)].
Topics: Carcinoma, Bronchogenic; Cobalt Radioisotopes; DNA; Glucuronidase; Hodgkin Disease; Humans; Lectins; | 1974 |
Activation of host lymphocytes cultured with cancer cells treated with neuraminidase.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Culture Tec | 1971 |
Immunologic impairment in bronchogenic carcinoma: a study of lymphocyte response to phytohemagglutinin.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Adult; Aged; Carcinoma; Carcinoma, Bronchogenic | 1972 |
Decline in mixed lymphocyte reactivity of spleen cells from aged mice of a long-lived strain.
Topics: Age Factors; Animals; Carcinoma; Carcinoma, Hepatocellular; Liver Neoplasms; Lung Neoplasms; Lymphoc | 1973 |
In vitro determination of thymidine-3H labeling index in human solid tumors.
Topics: Autoradiography; Carcinoma, Small Cell; Cell Division; Cell Survival; Cells, Cultured; DNA, Neoplasm | 1974 |
Growth regulation and tumour formation of normal and neoplastic rat cells.
Topics: Animals; Autoradiography; Cell Aggregation; Cell Division; Cell Movement; Cell Survival; Cell Transf | 1973 |
Neuraminidase and cell viability: failure to detect cytotoxic effects with dye-exclusion techniques.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Antigens, Neoplasm; Cell Division; Cell Survival; Cell | 1974 |
Cell kinetic studies in patients with small cell carcinoma of the lung.
Topics: Autoradiography; Biopsy; Bone Marrow; Carcinoma, Small Cell; Cell Division; Cyclohexanes; Cyclophosp | 1974 |
Cell kinetic studies in patients with lung cancer.
Topics: Adenocarcinoma; Autoradiography; Carcinoma; Carcinoma, Squamous Cell; Cell Division; DNA, Neoplasm; | 1974 |
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radi | 1974 |
Antigen solubilized from human solid tumours: lymphocyte stimulation and cutaneous delayed hypersensitivity.
Topics: Antigens, Neoplasm; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hodgkin Disease; Humans; | 1973 |
Age-related decline in response to phytohemagglutinin and pokeweed mitogen by spleen cells from hamsters and a long-lived mouse strain.
Topics: Adrenal Gland Neoplasms; Aging; Amyloidosis; Animals; B-Lymphocytes; Carcinoma; Cricetinae; Female; | 1973 |
Effect of 5-bromodeoxyuridine (BUdR) on experimental metastasis.
Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Clone Cells; Dose-Response Relationship, Drug; Ido | 1973 |
In vitro methods of assessing lymphocyte transformation in patients undergoing radiotherapy for bronchogenic cancer.
Topics: Carcinoma, Bronchogenic; Cells, Cultured; Cobalt Isotopes; DNA; Humans; Lectins; Leukocyte Count; Le | 1973 |
Correlation of histologic types with cell kinetic studies in lung cancer.
Topics: Abdominal Neoplasms; Adenocarcinoma; Autoradiography; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, | 1973 |
Separation of cells from a fibrosarcoma in renografin density gradients.
Topics: Amino Sugars; Animals; Cell Count; Cell Division; Cell Separation; Centrifugation, Density Gradient; | 1974 |
Immune surveillance and tumor dissemination: in vitro comparison of the B16 melanoma in primary and metastatic form.
Topics: Animals; Antigens, Neoplasm; Carbon Radioisotopes; Cell Transformation, Neoplastic; Cells; Cells, Cu | 1974 |
Duration of inhibition of synthesis of DNA in tumors and host tissues after single doses of nitrosoureas.
Topics: Animals; Bone Marrow; Brain; Carmustine; Cricetinae; Cyclohexanes; Depression, Chemical; DNA, Neopla | 1974 |
Cell population kinetics of transplanted and metastatic Lewis lung carcinoma.
Topics: Animals; Autoradiography; Cell Division; DNA, Neoplasm; Hybridization, Genetic; L-Lactate Dehydrogen | 1974 |
In vivo tumor cell kinetic studies: use of local thymidine injection followed by fine-needle aspiration.
Topics: Abdominal Neoplasms; Autoradiography; Biopsy; Humans; Inhalation; Lung Neoplasms; Methods; Needles; | 1972 |
Alterations in cell proliferation in mouse lung following urethane exposure. 3. Effects of chronic exposure on type 2 alveolar epithelial cell.
Topics: Animals; Autoradiography; Body Weight; Cell Division; Drinking; Epithelial Cells; Epithelium; Lung N | 1972 |
Response of DNA thymine synthesis in human tumor and normal tissue to 5-fluorouracil.
Topics: Breast Neoplasms; Carbon Isotopes; Chromatography, Paper; Colon; Colonic Neoplasms; Depression, Chem | 1972 |
Metabolism of 5-(3,3-dimethyl-1-triazeno)imidazole-4-carboxamide (NSC-45388) in human and animal tumor tissue.
Topics: Amides; Animals; Antineoplastic Agents; Carbohydrates; Carbon Isotopes; Chromatography, Thin Layer; | 1972 |
Analysis of the cell kinetics of human solid tumors.
Topics: Adult; Aged; Biopsy; Bone Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Colo | 1971 |
Alteration in cell proliferation in mouse lung following urethane exposure. II. Effects of chronic exposure on terminal bronchiolar epithelium.
Topics: Adenoma; Animals; Autoradiography; Bronchi; DNA; Environmental Exposure; Epithelial Cells; Epitheliu | 1971 |
Phytohemagglutinin (PHA)-induced transformation of lymphocytes from patients with cancer.
Topics: Adolescent; Adult; Age Factors; Child; Child, Preschool; DNA; Female; Genital Neoplasms, Female; Hod | 1971 |
The growth and cell population kinetics of spontaneous tumours in domestic animals.
Topics: Animals; Autoradiography; Cat Diseases; Cats; DNA, Neoplasm; Dog Diseases; Dogs; Female; Kidney Neop | 1969 |
Cell population kinetics and chemotherapy. I. The kinetics of tumor cell populations.
Topics: Animals; Autoradiography; Cell Division; DNA, Neoplasm; Dog Diseases; Dogs; Humans; Kinetics; Lung N | 1969 |
Postnatal cellular proliferation in mouse and hamster lung.
Topics: Adenoma; Animals; Animals, Newborn; Autoradiography; Cell Division; Cell Nucleus; Cricetinae; DNA; L | 1970 |
Kinetic parameters and growth curves for experimental tumor systems.
Topics: Adenocarcinoma; Animals; Autoradiography; Benz(a)Anthracenes; Carcinoma, Ehrlich Tumor; Female; Kine | 1970 |
Effect of therapeutic irradiation on lymphocyte transformation in lung cancer.
Topics: Cobalt Isotopes; Humans; Lectins; Leukocyte Count; Lung Neoplasms; Lymphocyte Activation; Lymphocyte | 1971 |
Cell kinetics and tumour formation. Cell turnover in the lungs of mice with hereditary lung tumours.
Topics: Animals; Cell Nucleus; DNA; DNA, Neoplasm; Female; Homeostasis; Lung; Lung Neoplasms; Male; Mice; Mi | 1968 |
Relation of thymidine index to pulmonary tumor response in mice receiving urethan and other carcinogens.
Topics: Animals; Autoradiography; Carbamates; Carcinogens; Cytarabine; Dactinomycin; DNA; Fluorouracil; Inje | 1969 |
[Current data on human tumor kinetics].
Topics: Animals; Ascites; Biopsy; Humans; Kinetics; Leukemia; Lung Neoplasms; Mammary Neoplasms, Experimenta | 1969 |
Urethan carcinogenesis and nucleic acid metabolism: factors influencing lung adenoma induction.
Topics: Aminopterin; Animals; Lung Neoplasms; Mice; Neoplasms, Experimental; Nucleic Acids; Orotic Acid; Thy | 1966 |
The fate of intravenously transfused, tritiumlabelled sarcoma cells in an isologous system.
Topics: Aminocaproates; Animals; Heparin; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplastic Cells, | 1966 |