thymidine has been researched along with Cancer of Head in 34 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Effects of lipophilic thymidylate synthase (TS) inhibitor AG337 on human head and neck squamous cell carcinoma (HNSCC) cell lines and CCRF-CEM human leukemia cells and sublines with acquired methotrexate (MTX) resistance were assayed using continuous or intermittent drug exposure." | 3.70 | Characterization of the effect of AG337, a novel lipophilic thymidylate synthase inhibitor, on human head and neck and human leukemia cell lines. ( Canestrari, JG; McGuire, JJ; Nagel, GS, 1999) |
| "Head and neck cancers are hard to detect due to non-specific symptoms." | 1.91 | Hybrids of 1,4-Naphthoquinone with Thymidine Derivatives: Synthesis, Anticancer Activity, and Molecular Docking Study. ( Halama, A; Kadela-Tomanek, M; Krzykawski, K; Kubina, R, 2023) |
| "Thirty-eight patients with advanced HNSCC underwent 11C-4DST PET/CT and 18F-FDG PET/CT before treatment." | 1.42 | Volumetric comparison of positron emission tomography/computed tomography using 4'-[methyl-¹¹C]-thiothymidine with 2-deoxy-2-¹⁸F-fluoro-D-glucose in patients with advanced head and neck squamous cell carcinoma. ( Ishiwata, K; Ito, K; Kubota, K; Minamimoto, R; Miyata, Y; Morooka, M; Okasaki, M; Toyohara, J; Yokoyama, J, 2015) |
| "In this group of patients with head and neck cancers, our results show that kinetic differences in various 11C-metabolites are small." | 1.29 | Measurement of [methyl-carbon-11]thymidine and its metabolites in head and neck tumors. ( Dams, R; Goethals, P; Lodewyck, W; van Eijkeren, M, 1995) |
| "In nine patients with squamous cell carcinoma of the head and neck, 11C-activity over the tumour and the adjacent blood vessels was measured." | 1.29 | Kinetics of [methyl-11C]thymidine in patients with squamous cell carcinoma of the head and neck. ( Goethals, P; Lemahieu, I; Seuntjens, J; Strijckmans, K; Thierens, H; van Eijkeren, ME, 1996) |
| "The chemosensitivity of various head and neck cancers was investigated with the 5-day rapid thymidine incorporation assay in soft agar culture." | 1.28 | Chemosensitivity of head and neck cancer with the rapid thymidine incorporation assay and its clinical application. ( Fujieda, S; Ohtsubo, T; Saito, H; Tanigawa, N, 1992) |
| "3H-Thymidine was mainly incorporated by endotheliocytes and pericytes, whereas Madelung's lipoma contained a greater number of labeled cells." | 1.27 | [Electron microscopic and radioautographic study of nucleic acid synthesis in normal fatty tissue and lipomas]. ( Adamian, AA; Kolokol'chikova, EG; Pal'tsyn, AA; Sarkisov, DS, 1984) |
| " Forty-eight hours after MTX dosage the level of 7-hydroxymethotrexate exceeded that of MTX by ten to one." | 1.26 | Methotrexate cytotoxicity: studies on its reversal by folates and nucleosides. ( Lankelma, J; Leyva, A; Nederbragt, H; Pinedo, HM, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (55.88) | 18.7374 |
| 1990's | 9 (26.47) | 18.2507 |
| 2000's | 4 (11.76) | 29.6817 |
| 2010's | 1 (2.94) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Kadela-Tomanek, M | 1 |
| Krzykawski, K | 1 |
| Halama, A | 1 |
| Kubina, R | 1 |
| Ito, K | 1 |
| Yokoyama, J | 1 |
| Miyata, Y | 1 |
| Toyohara, J | 1 |
| Okasaki, M | 1 |
| Minamimoto, R | 1 |
| Morooka, M | 1 |
| Ishiwata, K | 1 |
| Kubota, K | 1 |
| Tavassoli, M | 1 |
| Soltaninia, J | 1 |
| Rudnicka, J | 1 |
| Mashanyare, D | 1 |
| Johnson, N | 1 |
| Gäken, J | 1 |
| Harrington, KJ | 1 |
| Syrigos, KN | 1 |
| Uster, PS | 1 |
| Zetter, A | 1 |
| Lewanski, CR | 1 |
| Gullick, WJ | 1 |
| Vile, RG | 1 |
| Stewart, JS | 1 |
| Lu, J | 1 |
| Wang, LE | 1 |
| Xiong, P | 1 |
| Sturgis, EM | 1 |
| Spitz, MR | 1 |
| Wei, Q | 1 |
| Weidauer, H | 1 |
| Singer, R | 1 |
| Leyva, A | 2 |
| Nederbragt, H | 1 |
| Lankelma, J | 1 |
| Pinedo, HM | 2 |
| Sarkisov, DS | 1 |
| Pal'tsyn, AA | 1 |
| Adamian, AA | 1 |
| Kolokol'chikova, EG | 1 |
| Schornagel, JH | 1 |
| Tattersall, MH | 1 |
| Mashiba, H | 1 |
| Matsunaga, K | 1 |
| Yagawa, K | 1 |
| Nomura, Y | 1 |
| Yoshinaga, H | 1 |
| Furusawa, M | 1 |
| Jimi, S | 1 |
| Teuring, F | 1 |
| Dilkes, MG | 1 |
| McKelvie, P | 1 |
| Jones, T | 1 |
| Goethals, P | 3 |
| van Eijkeren, M | 1 |
| Lodewyck, W | 1 |
| Dams, R | 1 |
| van Eijkeren, ME | 2 |
| Thierens, H | 1 |
| Seuntjens, J | 1 |
| Lemahieu, I | 2 |
| Strijckmans, K | 1 |
| Cao, S | 1 |
| McGuire, JJ | 2 |
| Rustum, YM | 1 |
| Canestrari, JG | 1 |
| Nagel, GS | 1 |
| Shibuya, TY | 1 |
| Nugyen, N | 1 |
| McLaren, CE | 1 |
| Li, KT | 1 |
| Wei, WZ | 1 |
| Kim, S | 1 |
| Yoo, GH | 1 |
| Rogowski, A | 1 |
| Ensley, J | 1 |
| Sakr, W | 1 |
| Bertino, JR | 1 |
| Chang, TH | 1 |
| Liebeskind, D | 1 |
| Hsu, KC | 1 |
| Elequin, F | 1 |
| Janis, M | 1 |
| Bases, R | 1 |
| Straus, MJ | 1 |
| Straus, SE | 1 |
| Battiste, L | 1 |
| Krezoski, S | 1 |
| Saito, H | 1 |
| Ohtsubo, T | 1 |
| Fujieda, S | 1 |
| Tanigawa, N | 1 |
| De Schryver, A | 1 |
| Poupeye, E | 1 |
| Schelstraete, K | 1 |
| De Potter, CR | 1 |
| Awwad, HK | 1 |
| Khafagy, Y | 1 |
| Barsoum, M | 1 |
| Ezzat, S | 1 |
| el-Attar, I | 1 |
| Farag, H | 1 |
| Akoush, H | 1 |
| Meabid, H | 1 |
| Zaghloul, MS | 1 |
| Cook, JA | 1 |
| Glass, J | 1 |
| Lebovics, R | 1 |
| Bobo, H | 1 |
| Pass, H | 1 |
| DeLaney, TF | 1 |
| Oldfield, EH | 1 |
| Mitchell, JB | 1 |
| Glatstein, E | 1 |
| Goffman, TE | 1 |
| Chauvel, P | 2 |
| Courdi, A | 2 |
| Gioanni, J | 2 |
| Vallicioni, J | 1 |
| Santini, J | 1 |
| Demard, F | 2 |
| Héry, M | 1 |
| Namer, M | 1 |
| Greenberg, B | 1 |
| Woo, L | 1 |
| Blatchford, S | 1 |
| Aguirre, M | 1 |
| Garewal, H | 1 |
| Alama, A | 1 |
| Conte, PF | 1 |
| Di Marco, E | 1 |
| Favoni, RE | 1 |
| Nicolin, A | 1 |
| Wolberg, WH | 1 |
| Catalona, WJ | 2 |
| Sample, WF | 2 |
| Chretien, PB | 2 |
| Crowder, WL | 1 |
| Gertner, HR | 1 |
| Conger, AD | 1 |
| Wells, MA | 1 |
| Sako, K | 1 |
| Marchetta, FC | 1 |
1 review available for thymidine and Cancer of Head
| Article | Year |
|---|---|
[Results of primary antineoplastic chemotherapy in advanced keratinizing squamous epithelial carcinomas of the head and neck region].
Topics: Adult; Aged; Bleomycin; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Inosine; | 1981 |
2 trials available for thymidine and Cancer of Head
| Article | Year |
|---|---|
Current studies of methotrexate and 5-fluorouracil and their interaction in human tumor cells.
Topics: Animals; Cells, Cultured; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Drug The | 1983 |
Accelerated versus conventional fractionation in the postoperative irradiation of locally advanced head and neck cancer: influence of tumour proliferation.
Topics: Adult; Aged; Carcinoma, Squamous Cell; Cell Division; Combined Modality Therapy; Female; Head and Ne | 1992 |
31 other studies available for thymidine and Cancer of Head
| Article | Year |
|---|---|
Hybrids of 1,4-Naphthoquinone with Thymidine Derivatives: Synthesis, Anticancer Activity, and Molecular Docking Study.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antit | 2023 |
Volumetric comparison of positron emission tomography/computed tomography using 4'-[methyl-¹¹C]-thiothymidine with 2-deoxy-2-¹⁸F-fluoro-D-glucose in patients with advanced head and neck squamous cell carcinoma.
Topics: Aged; Carcinoma, Squamous Cell; Female; Fluorodeoxyglucose F18; Head and Neck Neoplasms; Humans; Ki- | 2015 |
Tamoxifen inhibits the growth of head and neck cancer cells and sensitizes these cells to cisplatin induced-apoptosis: role of TGF-beta1.
Topics: Apoptosis; Carcinoma, Squamous Cell; Cell Cycle; Cells, Cultured; Cisplatin; DNA, Neoplasm; G1 Phase | 2002 |
Targeted radiosensitisation by pegylated liposome-encapsulated 3', 5'-O-dipalmitoyl 5-iodo-2'-deoxyuridine in a head and neck cancer xenograft model.
Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Radiation; Drug Carriers; Female; Hea | 2004 |
172G>T variant in the 5' untranslated region of DNA repair gene RAD51 reduces risk of squamous cell carcinoma of the head and neck and interacts with a P53 codon 72 variant.
Topics: 5' Untranslated Regions; Adolescent; Adult; Aged; Aged, 80 and over; Binding Sites; Carcinoma, Squam | 2007 |
Methotrexate cytotoxicity: studies on its reversal by folates and nucleosides.
Topics: Animals; Biological Transport; Cell Membrane Permeability; Cells, Cultured; Head and Neck Neoplasms; | 1981 |
[Electron microscopic and radioautographic study of nucleic acid synthesis in normal fatty tissue and lipomas].
Topics: Adipose Tissue; Adult; Autoradiography; DNA; DNA, Neoplasm; Female; Head and Neck Neoplasms; Humans; | 1984 |
Methotrexate with thymidine protection or rescue in advanced head and neck cancer: a phase II study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Blood Cells; Digestive System; Drug Eva | 1984 |
Elevated cytostatic activity of monocytes from cancer patients.
Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cytotoxicity, Immunologic; Female; Head and Neck Neopla | 1981 |
[Method of invitro autoradiography for the diagnosis and control of the therapy of tumors].
Topics: Animals; Autoradiography; Female; Genital Neoplasms, Female; Head and Neck Neoplasms; Humans; In Vit | 1980 |
Investigation of cervical lymphadenopathy presumed to be metastatic in nature: a review of current clinical practice.
Topics: Head and Neck Neoplasms; Humans; Thymidine; Tomography, Emission-Computed | 1993 |
Measurement of [methyl-carbon-11]thymidine and its metabolites in head and neck tumors.
Topics: Adult; Aged; Head and Neck Neoplasms; Humans; Middle Aged; Thymidine; Tomography, Emission-Computed | 1995 |
Kinetics of [methyl-11C]thymidine in patients with squamous cell carcinoma of the head and neck.
Topics: Aged; Carbon Radioisotopes; Carcinoma, Squamous Cell; Contrast Media; Female; Head and Neck Neoplasm | 1996 |
Antitumor activity of ZD1694 (tomudex) against human head and neck cancer in nude mouse models: role of dosing schedule and plasma thymidine.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Drug Administration Schedule; Female; Floxur | 1999 |
Characterization of the effect of AG337, a novel lipophilic thymidylate synthase inhibitor, on human head and neck and human leukemia cell lines.
Topics: Cell Cycle; Cell Division; Culture Media; Drug Resistance; Enzyme Inhibitors; Fetal Blood; Head and | 1999 |
Clinical significance of poor CD3 response in head and neck cancer.
Topics: Carcinoma, Squamous Cell; CD3 Complex; Disease-Free Survival; Female; Head and Neck Neoplasms; Human | 2002 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru | 1977 |
Labeling index in clinical specimens estimated by the antinucleoside antibody technique.
Topics: Adenocarcinoma; Antibodies; Breast Neoplasms; DNA, Neoplasm; Female; Frozen Sections; Head and Neck | 1978 |
The uptake, excretion, and radiation hazards of tritiated thymidine in humans.
Topics: Adult; Aged; Bone Marrow; Bone Marrow Cells; Cell Division; DNA, Neoplasm; Half-Life; Head and Neck | 1977 |
Chemosensitivity of head and neck cancer with the rapid thymidine incorporation assay and its clinical application.
Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Bleomycin; Child; Cisplatin; Colonic Neopl | 1992 |
Measurement of short-term 11C-thymidine activity in human head and neck tumours using positron emission tomography (PET).
Topics: Adult; Aged; Carbon Radioisotopes; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans | 1992 |
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine.
Topics: Animals; Cell Line; Combined Modality Therapy; DNA, Neoplasm; Flow Cytometry; Glioma; Head and Neck | 1992 |
The labelling index: a prognostic factor in head and neck carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Autoradiography; Carcinoma, Squamous Cell; Cel | 1989 |
Prognostic value of continuous variables in breast cancer and head and neck cancer. Dependence on the cut-off level.
Topics: Breast Neoplasms; Female; Head and Neck Neoplasms; Humans; Interphase; Mitosis; Predictive Value of | 1988 |
Variability of the thymidine labeling index in squamous cell carcinoma of the head and neck.
Topics: Carcinoma, Squamous Cell; Cell Division; DNA, Neoplasm; Head and Neck Neoplasms; Humans; Kinetics; P | 1988 |
Proliferative activity of human solid tumors evaluated by thymidine labeling index and primer-dependent alpha-DNA polymerase.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cell Division; DNA Polymerase II; Female; Head and | 1986 |
Biochemical approaches to prediction of response in solid tumors.
Topics: Adenocarcinoma; Antineoplastic Agents; Carbon Isotopes; Carcinoma, Hepatocellular; Carcinoma, Squamo | 1971 |
Lymphocyte reactivity in cancer patients: correlation with tumor histology and clinical stage.
Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Antilymphocyte Serum; Carcinoma; Carcinoma, Sq | 1973 |
Correlation of preoperative lymphocyte reactivity with the clinical course of cancer patients.
Topics: Adenocarcinoma; Adolescent; Adult; Age Factors; Aged; Carcinoma, Squamous Cell; Follow-Up Studies; H | 1973 |
Radiation and aging effect on taste structure and function.
Topics: Aging; Animals; Head and Neck Neoplasms; Humans; Hydrochloric Acid; Mice; Quinine; Radiation Effects | 1969 |
Radioautography of in vitro labeled tumor cells in postoperative wound drainage.
Topics: Autoradiography; DNA, Neoplasm; Drainage; Head; Head and Neck Neoplasms; Humans; In Vitro Techniques | 1966 |