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thymidine and Cancer of Gastrointestinal Tract

thymidine has been researched along with Cancer of Gastrointestinal Tract in 15 studies

Research Excerpts

ExcerptRelevanceReference
" The thymidine analog trifluorothymidine (TFT) has been shown to bypass resistance pathways for 5FU derivatives (S-1, UFT, Xeloda) in model systems, while concurrent application with a thymidine phosphorylase inhibitor (TPI) increases the bioavailability of TFT, thereby potentiating the in vivo efficacy of TFT."2.44Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies. ( de Bruin, M; Emura, T; Fukushima, M; Peters, GJ; Temmink, OH, 2007)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's2 (13.33)18.2507
2000's3 (20.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yasui, H1
Tsurita, G1
Imai, K1
Wells, P1
Aboagye, E1
Gunn, RN1
Osman, S1
Boddy, AV1
Taylor, GA1
Rafi, I1
Hughes, AN1
Calvert, AH1
Price, PM1
Newell, DR1
Temmink, OH1
Emura, T1
de Bruin, M1
Fukushima, M1
Peters, GJ1
Hoffman, J1
Post, J1
Sunter, JP1
Ichihashi, H1
Kondo, T1
Sakakibara, S1
Akiyama, S1
Watanabe, T1
Matsuoka, H1
Yano, K1
Seo, Y1
Saito, T1
Tomoda, H1
Takiguchi, S1
Kono, A1
Jung, CP1
Motwani, MV1
Schwartz, GK1
Bertino, JR1
Lipkin, M1
Sekizuka, H1
Haki, K1
Iwasa, H1
Murakami, T1
DeConti, RC1
Toftness, BR1
Lange, RC1
Creasey, WA1
Buda, JA1
Suciu-Foca, N1
Reemtsma, KB1
Lejtenyi, MC1
Freedman, SO1
Gold, P1
Messinetti, S1
Zelli, GP1
Marcellino, LR1
Alcini, E1

Reviews

3 reviews available for thymidine and Cancer of Gastrointestinal Tract

ArticleYear
DNA synthesis inhibitors for the treatment of gastrointestinal cancer.
    Expert opinion on pharmacotherapy, 2014, Volume: 15, Issue:16

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protoco

2014
Therapeutic potential of the dual-targeted TAS-102 formulation in the treatment of gastrointestinal malignancies.
    Cancer science, 2007, Volume: 98, Issue:6

    Topics: Administration, Oral; Antimetabolites, Antineoplastic; Biological Availability; Clinical Trials as T

2007
Gastrointestinal cancer: pathogenesis, risk factors and the development of intermediate biomarkers for chemoprevention studies.
    Journal of cellular biochemistry. Supplement, 1992, Volume: 16G

    Topics: Anticarcinogenic Agents; Biomarkers, Tumor; Cell Division; China; Esophageal Neoplasms; Gastrointest

1992

Other Studies

12 other studies available for thymidine and Cancer of Gastrointestinal Tract

ArticleYear
2-[11C]thymidine positron emission tomography as an indicator of thymidylate synthase inhibition in patients treated with AG337.
    Journal of the National Cancer Institute, 2003, May-07, Volume: 95, Issue:9

    Topics: Adult; Aged; Antimetabolites, Antineoplastic; Area Under Curve; Carbon Radioisotopes; Case-Control S

2003
In vivo studies of DNA synthesis in human normal and tumor cells.
    Cancer research, 1967, Volume: 27, Issue:5

    Topics: Aged; Digestive System; DNA; DNA, Neoplasm; Female; Gastrointestinal Neoplasms; Humans; Injections,

1967
Cell proliferation in gastrointestinal carcinogenesis.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 104

    Topics: Animals; Autoradiography; Cell Division; Cell Transformation, Neoplastic; Colon; Colonic Neoplasms;

1984
Application of radioactive precursors for the evaluation of sensitivity of cancer cells to anticancer drugs.
    Oncology, 1984, Volume: 41, Issue:2

    Topics: Adult; Aged; Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Cell Line; Cell Survival; DNA

1984
Cytotoxicity of CPT-11 for gastrointestinal cancer cells cultured on fixed-contact-sensitive plates.
    Anti-cancer drugs, 1995, Volume: 6, Issue:3

    Topics: Animals; Antineoplastic Agents, Phytogenic; Camptothecin; Cell Survival; Colony-Forming Units Assay;

1995
Flavopiridol increases sensitization to gemcitabine in human gastrointestinal cancer cell lines and correlates with down-regulation of ribonucleotide reductase M2 subunit.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cyste

2001
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
    Seminars in oncology, 1977, Volume: 4, Issue:2

    Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru

1977
Effect of anticancer chemotherapy on the lymphocyte blastoid transformation.
    Gan, 1973, Volume: 64, Issue:5

    Topics: Adult; Aged; Animals; Bleomycin; Cyclophosphamide; Fluorouracil; Gastrointestinal Neoplasms; Humans;

1973
Clinical and pharmacological studies with cis-diamminedichloroplatinum (II).
    Cancer research, 1973, Volume: 33, Issue:6

    Topics: Adult; Aged; Amines; Antineoplastic Agents; Chlorides; DNA, Neoplasm; Female; Gastrointestinal Neopl

1973
Impaired cell-mediated immunity in patients with cancer.
    Surgical forum, 1974, Volume: 25, Issue:0

    Topics: Breast Neoplasms; Cells, Cultured; Gastrointestinal Neoplasms; Humans; Immunity, Cellular; Lectins;

1974
Response of lymphocytes from patients with gastrointestinal cancer to the carcinoembryonic antigen of the human digestive system.
    Cancer, 1971, Volume: 28, Issue:1

    Topics: Antibodies; Antigens; Antigens, Neoplasm; Digestive System; DNA; Endoderm; Esophageal Neoplasms; Fem

1971
[Triated thymidine histoautoradiographic study of adenomatous polyps and adenopapillomas of the large intestine in relation to their morphogenesis and their carcinomatous evolution].
    Annali italiani di chirurgia, 1967, Volume: 43, Issue:2

    Topics: Autoradiography; Gastrointestinal Neoplasms; Humans; Papilloma; Polyps; Precancerous Conditions; Thy

1967