thymidine has been researched along with Breast Cancer in 346 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To identify through a substudy of a larger, multicenter study of adjuvant treatment in primary operable breast cancer patients any possible correlation between cellular proliferation rate, measured by thymidine labeling index (TLI), and perioperative chemotherapy (periCT)." | 9.09 | Thymidine labeling index analysis in early breast cancer patients randomized to receive perioperative chemotherapy. ( Alama, A; Del Mastro, L; Gardin, G; Lionetto, R; Pronzato, P; Queirolo, P; Sertoli, MR; Vecchio, S; Venturini, M, 2001) |
| "To investigate the possible role of positron emission tomography (PET) with fluorine-18 fluorodeoxyglucose (FDG) in the prognostic evaluation of primary breast cancer, we studied 86 patients with T1-3 (TNM classification) breast tumours before surgery and compared the tumour FDG uptake, calculated as a standardized uptake value (SUV), with postoperative histopathological findings, steroid hormone receptor status of the tumour, thymidine labelling index (LI) and tissular expression of p53." | 9.08 | Association between [18F]fluorodeoxyglucose uptake and postoperative histopathology, hormone receptor status, thymidine labelling index and p53 in primary breast cancer: a preliminary observation. ( Agresti, R; Bogni, A; Bombardieri, E; Chiesa, C; Crippa, F; Daidone, MG; De Sanctis, V; Decise, D; Greco, M; Pascali, C; Seregni, E, 1998) |
| "The aim of our study was to evaluate the impact of metronidazole (MTZ) on cytotoxicity and DNA synthesis in MCF-7 (estrogen receptor positive) and MDA-MB-231 (estrogen receptor negative) breast cancer cell lines." | 7.79 | Metronidazole affects breast cancer cell lines. ( Car, H; Konończuk, J; Miltyk, W; Prokopiuk, S; Sadowska, A; Sawicka, D; Surażyński, A, 2013) |
| " To find an efficient and more cost-effective high-throughput method for analyzing the methylation profile in breast cancer, we developed a method that allows for the simultaneous detection of multiple target CpG residues by using thymidine-specific cleavage mass array on matrix-assisted laser desorption/ionization time-of-flight silicon chips." | 7.74 | High-throughput hacking of the methylation patterns in breast cancer by in vitro transcription and thymidine-specific cleavage mass array on MALDI-TOF silico-chip. ( Fan, AX; Haghighi, MM; Hahn, S; Holzgreve, W; Radpour, R; Torbati, PM; Zhong, XY, 2008) |
| "A novel amidine analogue of melphalan (AB4) was compared to its parent drug, melphalan in respect to cytotoxicity, DNA and collagen biosynthesis in MDA-MB-231 and MCF-7 human breast cancer cells." | 7.73 | Novel amidine analogue of melphalan as a specific multifunctional inhibitor of growth and metabolism of human breast cancer cells. ( Bielawska, A; Bielawski, K; Miltyk, W; Pałka, J; Sosnowska, K; Winnicka, K, 2006) |
| "The aim of this study is to evaluate the prognostic role of thymidine labeling index in patients with breast cancer." | 7.72 | Thymidine labeling index: prognostic role in breast cancer. ( Agizhali, B; Ahishali, B; Aydiner, A; Bilir, A; Cabioglu, N; Camlica, H; Eralp, Y; Kecer, M; Ozmen, V, 2004) |
| "The present retrospective study aims to determine the clinical value of thymidine labelling index (TLI) together with other established clinical and biological factors in 116 locally advanced breast cancer (LABC) patients treated with anthracycline-based neoadjuvant chemotherapy, surgery, adjuvant chemotherapy and radiotherapy." | 7.71 | Biological considerations in locally advanced breast cancer treated with anthracycline-based neoadjuvant chemotherapy: thymidine labelling index is an independent indicator of clinical outcome. ( Aydiner, A; Bilir, A; Bozfakioglu, Y; Cabioglu, N; Dagoglu, T; Dolay, K; Igci, A; Kecer, M; Muslumanoglu, M; Ozmen, V, 2001) |
| " The concentrations of 1, 2 and 3 needed to inhibit [1H]thymidine incorporation into DNA by 50% (IC50) in breast cancer MCF-7 cells were found to be 185 +/- 5 microM, 107 +/- 6 microM and 87 +/- 6 microM, respectively, suggesting a lower cytotoxic potency of these compounds compared to Hoechst 33228 (IC50 = 55 +/- 6 microM)." | 7.71 | Cytotoxicity activity of L-proline analogues of anthraquinone-2-carboxylic acid in breast cancer MCF-7 cells. ( Bielawska, A; Bielawski, K; Pałka, J, 2001) |
| "Previous studies have shown that acetaminophen, a common analgesic/antipyretic, induces proliferation of cultured breast cancer cells containing both estrogen and progesterone receptors (ER+/PR+)." | 7.70 | Acetaminophen-induced proliferation of breast cancer cells involves estrogen receptors. ( DeGeorge, GL; Gadd, SL; Harnagea-Theophilus, E; Knight-Trent, AH; Miller, MR, 1999) |
| "From 1982 to 1992, DNA synthesis was assessed by [3H]thymidine incorporation in 97 samples of primary lesions from 94 patients with breast cancer." | 7.70 | In vitro DNA synthesis in freshly separated human breast cancer cells assessed by tritiated thymidine incorporation assay: relationship to the long-term outcome of patients. ( Inamoto, T; Kan, N; Kodama, H; Nio, Y; Ohgaki, K; Tamura, K, 1999) |
| "The effect of indomethacin (INDO) with or without the addition of linoleic acid (LA) was investigated in a cultured MDA-MB-231 human breast cancer cell line." | 7.69 | Effects of indomethacin with or without linoleic acid on human breast cancer cells in vitro. ( Earashi, M; Miyazaki, I; Noguchi, M; Sasaki, T; Tanaka, M, 1995) |
| "These results indicate that the levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from peripheral nucleated blood may be potentially useful as a marker of breast cancer." | 7.69 | Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from blood as a marker of breast cancer. ( Djuric, Z; Heilbrun, LK; LoRusso, PM; Luongo, DA; Martino, S; Simon, MS; Smith, D, 1996) |
| "It has been shown that melatonin has a direct inhibitory effect on the proliferation of MCF-7 human breast cancer cells in culture." | 7.69 | Modulation of the length of the cell cycle time of MCF-7 human breast cancer cells by melatonin. ( Cos, S; Recio, J; Sánchez-Barceló, EJ, 1996) |
| "The aim of the present work was to study whether physiological doses of melatonin (1nM) modified DNA synthesis in MCF-7 human breast cancer cells." | 7.69 | Melatonin inhibits DNA synthesis in MCF-7 human breast cancer cells in vitro. ( Cos, S; Fernández, F; Sánchez-Barceló, EJ, 1996) |
| "Tumour growth rates, as measured by incorporation of tritiated thymidine, have been reported as being of prognostic importance in breast cancer." | 7.68 | Long-term prognostic significance of thymidine labelling index in primary breast cancer. ( Cooke, TG; Croton, R; George, WD; Holt, S; Murray, GD; Stanton, PD; Winstanley, J, 1992) |
| "The effects of aminoglutethimide, econazole and ketoconazole on human breast cancer cells in culture were compared with those of tamoxifen using four methods (growth experiments, thymidine incorporation, monoparameter and bivariate DNA content flow cytometry analysis)." | 7.68 | Comparative studies of steroidogenesis inhibitors (econazole, ketoconazole) on human breast cancer MCF-7 cell proliferation by growth experiments, thymidine incorporation and flow cytometric DNA analysis. ( Najid, A; Ratinaud, MH, 1991) |
| "The prognostic relevance of 3H-thymidine-labeling index (3H-TdR-LI) was retrospectively evaluated in 523 women with resectable node-positive breast cancer given adjuvant combination chemotherapy consisting of cyclophosphamide, methotrexate, and fluorouracil (CMF) +/- Adriamycin (doxorubicin; Farmitalia, Carlo Ezba, Italy)." | 7.68 | 3H-thymidine-labeling index as a prognostic indicator in node-positive breast cancer. ( Bonadonna, G; Daidone, MG; Di Fronzo, G; Mariani, L; Mezzanotte, G; Silvestrini, R; Valagussa, P, 1990) |
| "Using established breast cancer cell lines in a cell culture model we studied the growth effect of retinoic acid (RA) alone or in combination with the antiestrogen 4-hydroxytamoxifen (OHT)." | 7.67 | Effect of retinoic acid and 4-hydroxytamoxifen on human breast cancer cell lines. ( Daxenbichler, G; Marth, C; Mayer, I, 1984) |
| "Flow cytometric determination of tumor ploidy and S-phase fraction following collagenase dissociation and thymidine labeling was performed on 75 consecutive breast cancers." | 7.67 | A comparison of human breast cancer cell kinetics measured by flow cytometry and thymidine labeling. ( Craig, RB; McDivitt, RW; Meyer, JS; Stone, KR, 1985) |
| "Thirty-six patients with locally advanced breast cancer received diethylstilbestrol (1 mg/die) for 3 days followed by FAC (5 Fu 600 mg/m2, adriamycin 50 mg/m2, cytoxan 600 mg/m2) on day 4, q." | 7.67 | Cytokinetic parameters of locally advanced human breast cancer treated with diethylstilbestrol and chemotherapy. ( Alama, A; Canavese, G; Conte, PF; Di Marco, E; Nicolin, A; Rosso, R, 1986) |
| "We have approached the question of the reliability of the thymidine labeling index (TLI) of breast carcinoma by comparing paired samples." | 7.67 | Reliability and stability of the thymidine labeling index of breast carcinoma. ( McDivitt, RW; Meyer, JS, 1986) |
| "The in vitro Thymidine Labelling Index (TLI) of 164 primary breast carcinoma was measured." | 7.67 | In vitro thymidine labelling index in primary operable breast cancer. ( Cooke, TG; Croton, R; George, WD; Holt, S; Leinster, SJ; McDicken, I; Nicholson, RI, 1986) |
| " Oestradiol was inactive on endometrial cell multiplication as well as on their tritiated thymidine uptake, but in FAM breast cancer cells, we noticed a discrepancy between tritiated thymidine uptake and actual cell proliferation: there was a 40% increase in DNA precursor uptake, but no change in either the number of cells or in their DNA content, both of which were verified by two different methods." | 7.67 | Oestradiol is effective in stimulating 3H-thymidine incorporation but not on proliferation of breast cancer cultured cells. ( David, JF; Gay, G; Jozan, S; Marques, B; Mirouze, A, 1985) |
| "The site to site error and reproducibility of counting error have been assessed in the routine thymidine labelling of breast cancer." | 7.66 | The errors of thymidine labelling in breast cancer. ( Cooper, A; Smallwood, JA; Taylor, I, 1983) |
| "The effect of 17 beta-estradiol on cytoplasmic thymidine kinase activity was studied in MCF-7, a human breast cancer cell line in culture which responds to estrogens with an increase in the rate of growth." | 7.66 | Purification and properties of estrogen-responsive cytoplasmic thymidine kinase from human breast cancer. ( Aitken, S; Bronzert, DA; Lippman, ME; Monaco, ME; Pinkus, L, 1981) |
| "The effects of estrone, estradiol, and estriol on MCF-7 human breast cancer are compared." | 7.65 | Effects of estrone, estradiol, and estriol on hormone-responsive human breast cancer in long-term tissue culture. ( Bolan, G; Lippman, M; Monaco, ME, 1977) |
| "Palmitic acid was the main compound responsible for this apoptotic effect by a ceramide-independent mechanism that involved endoplasmic reticulum (ER)-stress with upregulation of CCAAT/-enhancer-binding protein homologous protein (CHOP)." | 5.39 | Palmitic acid and ergosta-7,22-dien-3-ol contribute to the apoptotic effect and cell cycle arrest of an extract from Marthasterias glacialis L. in neuroblastoma cells. ( Andrade, PB; Correia-da-Silva, G; Pereira, DM; Teixeira, N; Valentão, P, 2013) |
| "Paclitaxel (PTX) is a widely used chemotherapy agent and may cause cell death by apoptosis subsequent to microtubule (MT) disruption." | 5.34 | Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity. ( Fernando, R; Foster, JS; Henley, D; Isbill, M; Wimalasena, J, 2007) |
| "The effects of glucose and leptin on breast cancer cell proliferation were evaluated by examining cell doubling time, DNA synthesis, levels of cell cycle related proteins, protein kinase C (PKC) isozyme expression, and peroxisome proliferator-activated receptor (PPAR) subtypes were determined following glucose exposure at normal (5." | 5.31 | Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-alpha and PPAR expression. ( Cooper, DR; Jamali, M; Kojima, T; Maruyama, T; Okumura, M; Sakuma, H; Yamamoto, M; Yasuda, K, 2002) |
| "Obesity is a risk factor of breast cancers." | 5.31 | Leptin mediates a proliferative response in human MCF7 breast cancer cells. ( Dieudonne, MN; Giudicelli, Y; Leneveu, MC; Machinal-Quelin, F; Pecquery, R; Serazin-Leroy, V, 2002) |
| "In 3,800 node-negative breast cancers recruited between 1972 and 1991, the consistency of information provided by the 3H-thymidine labelling index (TLI), in terms of basic relations with other clinico-pathological and biological variables and clinical predictivity, was evaluated using a combined analysis of results previously published by our group for distinct series of patients." | 5.30 | Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index. ( Daidone, MG; Leutner, M; Luisi, A; Mastore, M; Salvadori, B; Silvestrini, R, 1997) |
| "Acetaminophen is a commonly used analgesic/antipyretic that also contains a p-phenol." | 5.30 | Acetaminophen alters estrogenic responses in vitro: stimulation of DNA synthesis in estrogen-responsive human breast cancer cells. ( Harnagea-Theophilus, E; Miller, MR, 1998) |
| "Gossypol is a polyphenolic aldehyde occurring naturally in cottonseed that produces antisteroidogenic activity in vivo, has been extensively investigated as a male contraceptive agent, and has demonstrated anticancer activity." | 5.29 | Antiproliferative activity of gossypol and gossypolone on human breast cancer cells. ( Brueggemeier, RW; Chang, CJ; Gilbert, NE; Lin, YC; O'Reilly, JE, 1995) |
| "One hundred thirty-two breast carcinomas were studied retrospectively using formalin fixed, paraffin embedded archival tissues on which S-LI and S-flow had been obtained originally." | 5.29 | Assessment of proliferating cell nuclear antigen (PCNA) in breast cancer using anti-PCNA PC10 and 19A2: correlation with 5-bromo-2'-deoxyuridine or tritiated thymidine labeling and flow cytometric analysis. ( He, W; Hughes, J; Koehm, S; Meyer, JS; Scrivner, DL, 1994) |
| "The LI of 234 consecutive breast carcinomas were measured with TT as was a subsequent series of 450 cases with BrdU, both by incubation in vitro." | 5.29 | Bromodeoxyuridine labeling for S-phase measurement in breast carcinoma. ( Higa, E; Hughes, JM; Koehm, SL; Lagos, JA; Manes, JL; Meyer, JS; Wittliff, JL, 1993) |
| "Treatment of Hs578T breast cancer cells with long chain saturated fatty acids (0." | 5.29 | Stearate inhibition of breast cancer cell proliferation. A mechanism involving epidermal growth factor receptor and G-proteins. ( Hardy, RW; Jo, H; McDonald, JM; Wickramasinghe, NS, 1996) |
| "The effects of pimozide on breast cancer cell growth were not limited to the MCF-7 cell line." | 5.28 | Inhibition of human breast cancer cell proliferation in tissue culture by the neuroleptic agents pimozide and thioridazine. ( Kirkwood, KL; Lantz, TK; Lewine, MA; Peterson, VA; Strobl, JS; Worley, JF, 1990) |
| "Sixty-four patients with breast cancer were the subjects studied." | 5.27 | Significance of the Tritiated Thymidine Labeling Index in breast cancers. ( Akagi, M; Araki, K; Kimura, M; Nishimura, R; Sakamoto, K, 1985) |
| "Phomopsin is a mycotoxin known to be carcinogenic." | 5.27 | Influence of phomopsin and ivalin on steroid-hormone binding and growth of MCF-7 human breast cancer cells. ( Lewko, WM; van Aswegen, CH; Wittliff, JL, 1985) |
| "EGF had no effect on another human breast cancer cell line, the MDA-231." | 5.26 | Epidermal growth factor stimulation of human breast cancer cells in culture. ( Hamilton, B; Livingston, RB; Osborne, CK; Titus, G, 1980) |
| "[3H]-Thymidine was administered in vivo." | 5.26 | Estrogen receptor heterogeneity and the relationship between estrogen receptor and the tritiated thymidine labeling index in human breast cancer. ( Moran, R; Muller, RE; Straus, MJ; Wotiz, HH, 1982) |
| "To identify through a substudy of a larger, multicenter study of adjuvant treatment in primary operable breast cancer patients any possible correlation between cellular proliferation rate, measured by thymidine labeling index (TLI), and perioperative chemotherapy (periCT)." | 5.09 | Thymidine labeling index analysis in early breast cancer patients randomized to receive perioperative chemotherapy. ( Alama, A; Del Mastro, L; Gardin, G; Lionetto, R; Pronzato, P; Queirolo, P; Sertoli, MR; Vecchio, S; Venturini, M, 2001) |
| "To investigate the possible role of positron emission tomography (PET) with fluorine-18 fluorodeoxyglucose (FDG) in the prognostic evaluation of primary breast cancer, we studied 86 patients with T1-3 (TNM classification) breast tumours before surgery and compared the tumour FDG uptake, calculated as a standardized uptake value (SUV), with postoperative histopathological findings, steroid hormone receptor status of the tumour, thymidine labelling index (LI) and tissular expression of p53." | 5.08 | Association between [18F]fluorodeoxyglucose uptake and postoperative histopathology, hormone receptor status, thymidine labelling index and p53 in primary breast cancer: a preliminary observation. ( Agresti, R; Bogni, A; Bombardieri, E; Chiesa, C; Crippa, F; Daidone, MG; De Sanctis, V; Decise, D; Greco, M; Pascali, C; Seregni, E, 1998) |
| " We previously discovered that 5-(α-substituted-2-nitrobenzyloxy)methyluridine-5'-triphosphates were exquisite DNA synthesis terminators; therefore, we synthesized a library of 35 thymidine analogs and evaluated their activity using an MTT cell viability assay of MCF7 breast cancer cells chosen for their vulnerability to these nucleoside derivatives." | 3.81 | Base-modified thymidines capable of terminating DNA synthesis are novel bioactive compounds with activity in cancer cells. ( AbdulSalam, SF; Andersen, JM; Bercz, AP; Borland, KM; Burke, MP; Gurjar, PN; Lawson, SM; Litosh, VA; Merino, EJ; Smith, S; Solivio, MJ; Stockman, CA; Tolstolutskaya, JN; Wolfkiel, PR, 2015) |
| "The aim of our study was to evaluate the impact of metronidazole (MTZ) on cytotoxicity and DNA synthesis in MCF-7 (estrogen receptor positive) and MDA-MB-231 (estrogen receptor negative) breast cancer cell lines." | 3.79 | Metronidazole affects breast cancer cell lines. ( Car, H; Konończuk, J; Miltyk, W; Prokopiuk, S; Sadowska, A; Sawicka, D; Surażyński, A, 2013) |
| "Metabolomic fingerprint of breast cancer cells treated with the antidiabetic drug metformin revealed a significant accumulation of 5-formimino-tetrahydrofolate, one of the tetrahydrofolate forms carrying activated one-carbon units that are essential for the de novo synthesis of purines and pyrimidines." | 3.78 | Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs. ( Corominas-Faja, B; Cufí, S; Joven, J; Martin-Castillo, B; Menendez, JA; Micol, V; Oliveras-Ferraros, C; Quirantes-Piné, R; Segura-Carretero, A; Vazquez-Martin, A, 2012) |
| " The effects of 5-fluorouracil (5-FU), doxorubicin and paclitaxel on FDG and FLT uptake were measured in MDA MB231 human breast cancer cells in relation to cell cycle distribution, expression and enzyme activity of TK-1." | 3.74 | [18F]FDG and [18F]FLT uptake in human breast cancer cells in relation to the effects of chemotherapy: an in vitro study. ( Balzarini, J; Berndsen, SC; Direcks, WG; Lammertsma, AA; Molthoff, CF; Peters, GJ; Proost, N; Spreeuwenberg, MD, 2008) |
| " To find an efficient and more cost-effective high-throughput method for analyzing the methylation profile in breast cancer, we developed a method that allows for the simultaneous detection of multiple target CpG residues by using thymidine-specific cleavage mass array on matrix-assisted laser desorption/ionization time-of-flight silicon chips." | 3.74 | High-throughput hacking of the methylation patterns in breast cancer by in vitro transcription and thymidine-specific cleavage mass array on MALDI-TOF silico-chip. ( Fan, AX; Haghighi, MM; Hahn, S; Holzgreve, W; Radpour, R; Torbati, PM; Zhong, XY, 2008) |
| " Evaluation of the cytotoxicity of these compounds employing a MTT assay and inhibition of [(3)H]thymidine incorporation into DNA in both MDA-MB-231 and MCF-7 human breast cancer cells demonstrated that these compounds were more active than melphalan." | 3.74 | Amidine analogues of melphalan: synthesis, cytotoxic activity, and DNA binding properties. ( Anchim, T; Bielawska, A; Bielawski, K, 2007) |
| "A novel amidine analogue of melphalan (AB4) was compared to its parent drug, melphalan in respect to cytotoxicity, DNA and collagen biosynthesis in MDA-MB-231 and MCF-7 human breast cancer cells." | 3.73 | Novel amidine analogue of melphalan as a specific multifunctional inhibitor of growth and metabolism of human breast cancer cells. ( Bielawska, A; Bielawski, K; Miltyk, W; Pałka, J; Sosnowska, K; Winnicka, K, 2006) |
| "The aim of this study is to evaluate the prognostic role of thymidine labeling index in patients with breast cancer." | 3.72 | Thymidine labeling index: prognostic role in breast cancer. ( Agizhali, B; Ahishali, B; Aydiner, A; Bilir, A; Cabioglu, N; Camlica, H; Eralp, Y; Kecer, M; Ozmen, V, 2004) |
| " The effect of both compounds on the proliferation of cells of the hormone sensitive human breast cancer cell line (ER+) MCF-7 was assessed in the presence of estradiol and tamoxifen." | 3.72 | Can transforming growth factor-beta1 and retinoids modify the activity of estradiol and antiestrogens in MCF-7 breast cancer cells?. ( Anchim, T; Czeczuga-Semeniuk, E; Dabrowska, M; Dziecioł, J; Wołczyński, S, 2004) |
| "In this paper we report the behaviour of normal vascular smooth muscle cells and transformed breast cancer cells under normal versus simulated microgravity conditions by comparing cell proliferation, Glucose transport, Methionine uptake and protein synthesis." | 3.72 | Microgravity alters basal and insulin-mediated metabolic activity of normal and neoplastic cells. ( Chiaviello, A; Coinu, R; Covelli, B; Galleri, G; Meloni, M; Palumbo, G; Pippia, P; Tilocca, MG, 2004) |
| " The present study is aimed to determine whether ginsenoside Rg1 can act like an estrogen analog in stimulating human breast cancer cell growth as well as in the activation of estrogen response element-luciferase activity in HeLa cell." | 3.71 | Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng. ( Chan, RY; Chen, WF; Dong, A; Guo, D; Wong, MS, 2002) |
| "In order to evaluate if breast cancer biological characteristics undergo significant menstrual and seasonal variations, we analysed in a consecutive series of 905 breast cancer patients, steroid receptor level (ER and PgR by DCC assay), proliferative activity (3H-Thymidine Labeling Index, 3H-TLI) and size of primary tumour in relation to calendar date and day of menstrual cycle at the time of the surgical procedure." | 3.71 | Predictability of monthly and yearly rhythms of breast cancer features. ( Cellamare, G; Fanelli, M; Mangia, A; Paradiso, A; Schittulli, F; Serio, G, 2001) |
| "The effects of vasoactive intestinal peptide (VIP) antagonists on breast cancer cells were investigated." | 3.71 | VIP receptor antagonists and chemotherapeutic drugs inhibit the growth of breast cancer cells. ( Brenneman, DC; Chan, D; Fridkin, M; Gelber, E; Gozes, I; Levy, A; Leyton, J; Moody, TW, 2001) |
| "The present retrospective study aims to determine the clinical value of thymidine labelling index (TLI) together with other established clinical and biological factors in 116 locally advanced breast cancer (LABC) patients treated with anthracycline-based neoadjuvant chemotherapy, surgery, adjuvant chemotherapy and radiotherapy." | 3.71 | Biological considerations in locally advanced breast cancer treated with anthracycline-based neoadjuvant chemotherapy: thymidine labelling index is an independent indicator of clinical outcome. ( Aydiner, A; Bilir, A; Bozfakioglu, Y; Cabioglu, N; Dagoglu, T; Dolay, K; Igci, A; Kecer, M; Muslumanoglu, M; Ozmen, V, 2001) |
| " The aim of this study was to compare the antiproliferative activity of various concentrations of 13-cis retinoic acid (isotretinoin) and all-trans retinoic acid (tretinoin) in a culture of the estrogen-sensitive human breast cancer cell line MCF-7." | 3.71 | 13-cis retinoic acid and all-trans retinoic acid in the regulation of the proliferation and survival of human breast cancer cell line MCF-7. ( Anchim, T; Czeczuga-Semeniuk, E; Dabrowska, M; Dziecioł, J; Tomaszewska, I; Wolczyński, S, 2001) |
| " The concentrations of 1, 2 and 3 needed to inhibit [1H]thymidine incorporation into DNA by 50% (IC50) in breast cancer MCF-7 cells were found to be 185 +/- 5 microM, 107 +/- 6 microM and 87 +/- 6 microM, respectively, suggesting a lower cytotoxic potency of these compounds compared to Hoechst 33228 (IC50 = 55 +/- 6 microM)." | 3.71 | Cytotoxicity activity of L-proline analogues of anthraquinone-2-carboxylic acid in breast cancer MCF-7 cells. ( Bielawska, A; Bielawski, K; Pałka, J, 2001) |
| " Human breast cancer cell lines (ZR-75-1, SK-BR-3, MCF-7) and a benign cell line (HBL-100) were used to study the hourly thymidine uptake as a measure of cells in synthesis." | 3.71 | Short-term rhythmic proliferation of human breast cancer cell lines: surface effects and fractal growth patterns. ( Budinsky, AC; Köstler, WJ; Sedivy, R; Thurner, S; Zielinski, CC, 2002) |
| " The acid-sensitive albumin conjugates prepared with the carboxylic hydrazone doxorubicin derivatives exhibited an inhibitory efficacy in the MDA-MB-468 breast cancer cell line and U937 leukemia cell line comparable with that of the free drug (using the BrdU-(5-bromo-2'-deoxyuridine)-incorporation assay and tritiated thymidine incorporation assay respectively, IC50 approximately 0." | 3.70 | Preparation, characterization and in vitro efficacy of albumin conjugates of doxorubicin. ( Beyer, U; Cazabat, A; Collery, P; Falken, U; Kratz, F; Lechenault, F; Schumacher, P; Unger, C, 1998) |
| "Previous studies have shown that acetaminophen, a common analgesic/antipyretic, induces proliferation of cultured breast cancer cells containing both estrogen and progesterone receptors (ER+/PR+)." | 3.70 | Acetaminophen-induced proliferation of breast cancer cells involves estrogen receptors. ( DeGeorge, GL; Gadd, SL; Harnagea-Theophilus, E; Knight-Trent, AH; Miller, MR, 1999) |
| "From 1982 to 1992, DNA synthesis was assessed by [3H]thymidine incorporation in 97 samples of primary lesions from 94 patients with breast cancer." | 3.70 | In vitro DNA synthesis in freshly separated human breast cancer cells assessed by tritiated thymidine incorporation assay: relationship to the long-term outcome of patients. ( Inamoto, T; Kan, N; Kodama, H; Nio, Y; Ohgaki, K; Tamura, K, 1999) |
| "Although tamoxifen is approved for the treatment of hormone-dependent breast cancer as well as for the prevention of breast cancer in high-risk women, several studies in animal models have shown that tamoxifen is heptocarcinogenic, and in humans, tamoxifen has been associated with an increased risk of endometrial cancer." | 3.70 | Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone. ( Bolton, JL; Fan, PW; Liu, X; Shen, L; van Breemen, RB; Zhang, F, 2000) |
| " In the present study, the correlation between [3H]thymidine labelling index ([3H]dT LI), flow cytometric S phase cell fraction (FCM-S) and Ki-67 immunoreactivity (Ki-67/MIB-1) was verified and the type of correlation with the most important clinical, pathological and biological patient and tumour characteristics was investigated in a very large series of breast cancer patients." | 3.70 | Comparison between different cell kinetic variables in human breast cancer. ( Aldi, M; Amadori, D; Barzanti, F; Bernardi, L; Dal Susino, M; Gaudio, M; Medri, L; Naldi, S; Riccobon, A; Scarpi, E; Volpi, A; Zoli, W, 2000) |
| "The effect of indomethacin (INDO) with or without the addition of linoleic acid (LA) was investigated in a cultured MDA-MB-231 human breast cancer cell line." | 3.69 | Effects of indomethacin with or without linoleic acid on human breast cancer cells in vitro. ( Earashi, M; Miyazaki, I; Noguchi, M; Sasaki, T; Tanaka, M, 1995) |
| "The relationship of changes in 3H-thymidine labelling index (TLI) induced by primary chemotherapy to tumor response and relapse rate in 36 patients with previously untreated locally advanced breast cancer (LABC) was analyzed." | 3.69 | Relationship of variations in tumor cell kinetics induced by primary chemotherapy to tumor regression and prognosis in locally advanced breast cancer. ( Alama, A; Camoriano, A; Campora, E; Gardin, G; Meazza, R; Merlini, L; Naso, C; Pronzato, P; Repetto, L; Rosso, R, 1994) |
| "Previous studies have shown that natural polyamines-putrescine, spermidine, and spermine-play a key role in the mechanism of action of estrogens in breast cancer." | 3.69 | Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications. ( Thomas, T; Thomas, TJ, 1994) |
| "These results indicate that the levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from peripheral nucleated blood may be potentially useful as a marker of breast cancer." | 3.69 | Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from blood as a marker of breast cancer. ( Djuric, Z; Heilbrun, LK; LoRusso, PM; Luongo, DA; Martino, S; Simon, MS; Smith, D, 1996) |
| "It has been shown that melatonin has a direct inhibitory effect on the proliferation of MCF-7 human breast cancer cells in culture." | 3.69 | Modulation of the length of the cell cycle time of MCF-7 human breast cancer cells by melatonin. ( Cos, S; Recio, J; Sánchez-Barceló, EJ, 1996) |
| "The aim of the present work was to study whether physiological doses of melatonin (1nM) modified DNA synthesis in MCF-7 human breast cancer cells." | 3.69 | Melatonin inhibits DNA synthesis in MCF-7 human breast cancer cells in vitro. ( Cos, S; Fernández, F; Sánchez-Barceló, EJ, 1996) |
| " Because epidemiologic studies have linked colon and breast cancer and aberrant bile acid profiles are associated with colon cancer risk, we decided to study the influence of bile acid conjugates (glycochenodeoxycholic acid, glycodeoxycholic acid, glycocholic acid, and glycolithocholic acid) on thymidine incorporation into DNA in cancer (MCF-7) and noncancer (MCF-10A) human mammary cell lines." | 3.69 | Effect of bile acids and estradiol on thymidine incorporation into DNA in MCF-7 and MCF-10A breast cell lines. ( Katz, J; Levitz, M; Raju, U, 1997) |
| " In contrast to PNA, ABL (25 micrograms/ml) inhibited incorporation of [3H]-thymidine into DNA of HT29 colon cancer cells by 87% (95% confidence limit, 85-89%), Caco-2 colon cancer cells by 16% (95% confidence limit, 12-20%), MCF-7 breast cancer cells by 50% (95% confidence limit, 47-52%), and Rama-27 rat mammary fibroblasts by 55% (95% confidence limit, 51-60%) when these cells were grown for 24 h in serum-free medium." | 3.68 | Reversible inhibition of proliferation of epithelial cell lines by Agaricus bisporus (edible mushroom) lectin. ( Fernig, DG; Milton, JD; Rhodes, JM; Smith, JA; Yu, L, 1993) |
| "In a series of 340 women with resectable node-negative breast cancers given local-regional therapy alone until relapse, proliferative activity was determined as the 3H-thymidine labeling index (3H-dT LI) and flow-cytometric S-phase cell fraction (FCM-S), as quantified by using different modeling systems." | 3.68 | Prognostic significance of proliferative activity and ploidy in node-negative breast cancers. ( Boracchi, P; Daidone, MG; Del Bino, G; Di Fronzo, G; Luisi, A; Mastore, M; Silvestrini, R, 1993) |
| "The fraction of cells that incorporate 3H-thymidine (3H-dT labeling index [3H-dT LI]) proved to be a prognostic indicator in patients with node-negative and node-positive resectable breast cancers treated with locoregional treatment alone or with adjuvant combination chemotherapy." | 3.68 | Cell kinetics as a predictive factor in node-positive breast cancer treated with adjuvant hormone therapy. ( Boracchi, P; Coradini, D; Daidone, MG; Di Fronzo, G; Mastore, M; Salvadori, B; Silvestrini, R; Squicciarini, P; Veronesi, U, 1993) |
| "Proliferative activity, evaluated as [3H]thymidine labelling index ([3H]dT LI), and hormone receptors were determined on 97 primary breast cancers and on metachronous lesions from the same patient." | 3.68 | Biological characterisation of primary and metachronous lesions in breast cancer patients. ( Coradini, D; Daidone, MG; Di Fronzo, G; Salvadori, B; Silvestrini, R; Valentinis, B, 1992) |
| " In this way, we obtained images showing the characteristic distribution of 14C-thymidine and D-arginine in human fibroblasts, and of 15N-adenine in organotypic cultures of human breast cancer cells." | 3.68 | Mapping the cellular distribution of labelled molecules by SIMS microscopy. ( Beaupain, R; Coulomb, B; Galle, P; Hindie, E, 1992) |
| "Tumour growth rates, as measured by incorporation of tritiated thymidine, have been reported as being of prognostic importance in breast cancer." | 3.68 | Long-term prognostic significance of thymidine labelling index in primary breast cancer. ( Cooke, TG; Croton, R; George, WD; Holt, S; Murray, GD; Stanton, PD; Winstanley, J, 1992) |
| "The evaluability and reliability of proliferative activity (expressed as 3H-thymidine labeling index, 3H-TdR LI) and ploidy determinations on core needle biopsies were compared with those obtained on surgical material from the same breast cancers." | 3.68 | Comparing core needle to surgical biopsies in breast cancer for cell kinetic and ploidy studies. ( Daidone, MG; Mastore, M; Orefice, S; Salvadori, B; Santoro, G; Silvestrini, R, 1991) |
| "The effects of aminoglutethimide, econazole and ketoconazole on human breast cancer cells in culture were compared with those of tamoxifen using four methods (growth experiments, thymidine incorporation, monoparameter and bivariate DNA content flow cytometry analysis)." | 3.68 | Comparative studies of steroidogenesis inhibitors (econazole, ketoconazole) on human breast cancer MCF-7 cell proliferation by growth experiments, thymidine incorporation and flow cytometric DNA analysis. ( Najid, A; Ratinaud, MH, 1991) |
| "The time course of DNA repair, using (3H)thymidine uptake as parameter, was measured during 8 h after a single exposure to 2, 8, and 16 UV-C J/m2 in lymphocytes of 8 cancer patients, 1 xeroderma pigmentosum patient and 10 controls." | 3.68 | Differences in the kinetics of DNA repair in cancer patients and healthy controls. ( Kovacs, E; Langemann, H, 1991) |
| " The direct effect of folligen and a well-known superactive GnRH analogue, buserelin, on the MDA-MB-231 human breast cancer cell line was investigated." | 3.68 | Gonadotropin-releasing hormone analogues inhibit cell proliferation and activate signal transduction pathways in MDA-MB-231 human breast cancer cell line. ( Balogh, A; Csuka, O; Kéri, G; Szöke, B; Teplán, I, 1991) |
| "In this report the effect of epidermal growth factor (EGF) and the antiestrogen hydroxytamoxifen (OH-TAM) on the cell cycle of the breast cancer cell line MCF-7 was investigated as a function of the presence of their respective receptors." | 3.68 | Cell cycle phase dependence of estrogen and epidermal growth factor (EGF) receptor expression in MCF-7 cells: implications in antiestrogen and EGF cell responsiveness. ( Berthois, Y; Colomb, E; Dong, XF; Martin, PM, 1991) |
| "Changes in the 3H-thymidine labelling index (3H-TdR LI) of primary tumor induced by cytoreductive chemotherapy were evaluated in 26 patients with locally advanced breast cancer subjected to mastectomy after different systemic therapies." | 3.68 | Changes in cell kinetics induced by primary chemotherapy in breast cancer. ( Bartoli, C; Daidone, MG; Ferrari, L; Silvestrini, R; Valentinis, B, 1991) |
| "The influence of endocrine therapy on the proliferation of estrogen receptor (ER)-positive cells and ER-negative cells of human breast cancer (MFC-7) serially transplanted into nude mice was analyzed by tumor growth, dextran-coated charcoal (DCC) method, ER-immunocytochemical assay (ER-ICA) and ER-immunocytochemically stained 3H-thymidine autoradiography." | 3.68 | Influence of hormones on proliferation of ER-positive cells and ER-negative cells of human breast cancer (MCF-7). ( Ashikari, A; Kumaki, T; Miyazaki, I; Noguchi, M; Tajiri, K; Taniya, T, 1990) |
| "Breast cancer cell lines (MCF-7, T47D, BT-20 and STT-11) and fresh cells from malignant effusions of eight breast cancer patients were examined for their in vitro sensitivity to 17 beta-estradiol (E2), tamoxifen and toremifene in a miniaturized, improved nucleic acid precursor incorporation assay (MINI assay)." | 3.68 | In vitro sensitivity test of breast cancer cells to hormonal agents in a radionucleotide-incorporation assay. ( Abe, K; Adachi, I; Fuchigami, M; Kuranami, M; Morikawa, K; Watanabe, T; Wu, JZ; Yamaguchi, K, 1990) |
| "Age-related changes in the activity of thymidine- and adenosine-metabolizing enzymes were studied in healthy females and those with breast cancer aged 46-70 years." | 3.68 | [Activity of the enzymes of DNA metabolism in the blood of patients with breast cancer]. ( Borzenko, BG; Dumanskiĭ, IuV; Gorbachev, AA; Shepliakov, MN; Shevchenko, VV, 1990) |
| "The prognostic relevance of 3H-thymidine-labeling index (3H-TdR-LI) was retrospectively evaluated in 523 women with resectable node-positive breast cancer given adjuvant combination chemotherapy consisting of cyclophosphamide, methotrexate, and fluorouracil (CMF) +/- Adriamycin (doxorubicin; Farmitalia, Carlo Ezba, Italy)." | 3.68 | 3H-thymidine-labeling index as a prognostic indicator in node-positive breast cancer. ( Bonadonna, G; Daidone, MG; Di Fronzo, G; Mariani, L; Mezzanotte, G; Silvestrini, R; Valagussa, P, 1990) |
| "Using established breast cancer cell lines in a cell culture model we studied the growth effect of retinoic acid (RA) alone or in combination with the antiestrogen 4-hydroxytamoxifen (OHT)." | 3.67 | Effect of retinoic acid and 4-hydroxytamoxifen on human breast cancer cell lines. ( Daxenbichler, G; Marth, C; Mayer, I, 1984) |
| "Thymidine labeling index (TLI) and Ki-67 growth fraction (KGF) are two indicators of proliferative activity in breast cancer." | 3.67 | Thymidine labeling index and Ki-67 growth fraction in lesions of the breast. ( Franklin, WA; Kamel, OW; Meyer, JS; Ringus, JC, 1989) |
| "Flow cytometric determination of tumor ploidy and S-phase fraction following collagenase dissociation and thymidine labeling was performed on 75 consecutive breast cancers." | 3.67 | A comparison of human breast cancer cell kinetics measured by flow cytometry and thymidine labeling. ( Craig, RB; McDivitt, RW; Meyer, JS; Stone, KR, 1985) |
| "Thirty-six patients with locally advanced breast cancer received diethylstilbestrol (1 mg/die) for 3 days followed by FAC (5 Fu 600 mg/m2, adriamycin 50 mg/m2, cytoxan 600 mg/m2) on day 4, q." | 3.67 | Cytokinetic parameters of locally advanced human breast cancer treated with diethylstilbestrol and chemotherapy. ( Alama, A; Canavese, G; Conte, PF; Di Marco, E; Nicolin, A; Rosso, R, 1986) |
| "Flow cytometric DNA analysis was performed on 168 consecutive primary operable breast cancers and the results correlated with thymidine labeling, estrogen receptor (ER) and progesterone receptor values, and various histologic parameters." | 3.67 | A proposed classification of breast cancer based on kinetic information: derived from a comparison of risk factors in 168 primary operable breast cancers. ( Bauer, WC; Craig, RB; McDivitt, RW; Meyer, JS; Palmer, JO; Stone, KR, 1986) |
| "We have approached the question of the reliability of the thymidine labeling index (TLI) of breast carcinoma by comparing paired samples." | 3.67 | Reliability and stability of the thymidine labeling index of breast carcinoma. ( McDivitt, RW; Meyer, JS, 1986) |
| "The in vitro Thymidine Labelling Index (TLI) of 164 primary breast carcinoma was measured." | 3.67 | In vitro thymidine labelling index in primary operable breast cancer. ( Cooke, TG; Croton, R; George, WD; Holt, S; Leinster, SJ; McDicken, I; Nicholson, RI, 1986) |
| " Oestradiol was inactive on endometrial cell multiplication as well as on their tritiated thymidine uptake, but in FAM breast cancer cells, we noticed a discrepancy between tritiated thymidine uptake and actual cell proliferation: there was a 40% increase in DNA precursor uptake, but no change in either the number of cells or in their DNA content, both of which were verified by two different methods." | 3.67 | Oestradiol is effective in stimulating 3H-thymidine incorporation but not on proliferation of breast cancer cultured cells. ( David, JF; Gay, G; Jozan, S; Marques, B; Mirouze, A, 1985) |
| "We have evaluated the feasibility of a cytokinetically oriented regimen based on the induction of cell recruitment by diethylstilbestrol (DES) in locally advanced human breast cancer." | 3.67 | Chemotherapy following estrogen-induced expansion of the growth fraction of human breast cancer. ( Alama, A; Canavese, G; Conte, PF; Corsaro, E; Drewinko, B; Fraschini, G; Nicolin, A; Rosso, R, 1985) |
| "The site to site error and reproducibility of counting error have been assessed in the routine thymidine labelling of breast cancer." | 3.66 | The errors of thymidine labelling in breast cancer. ( Cooper, A; Smallwood, JA; Taylor, I, 1983) |
| "An autoradiographic technique has been developed to determine the percentage of MCF-7 human breast adenocarcinoma cells in double-layer agar (DLA) culture that exhibit nuclear incorporation of 3H-thymidine (3H-TdR) after in vitro drug exposure." | 3.66 | Methods for determining chemosensitivity of MCF-7 cells in double-layer agar culture: labeling index depression and colony count inhibition. ( Elson, DL; Livingston, RB; Osborne, CK; Von Hoff, DD, 1982) |
| "The effect of 17 beta-estradiol on cytoplasmic thymidine kinase activity was studied in MCF-7, a human breast cancer cell line in culture which responds to estrogens with an increase in the rate of growth." | 3.66 | Purification and properties of estrogen-responsive cytoplasmic thymidine kinase from human breast cancer. ( Aitken, S; Bronzert, DA; Lippman, ME; Monaco, ME; Pinkus, L, 1981) |
| "The chemotherapeutic activity of thymidine (dThd) was tested against four human tumor xenografts growing in nude mice, including a melanoma, an oat cell carcinoma of the lung, a colon carcinoma, and a breast carcinoma." | 3.66 | Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice. ( Howell, SB; Jenkins, RS; Streifel, J, 1979) |
| "The effects of estrone, estradiol, and estriol on MCF-7 human breast cancer are compared." | 3.65 | Effects of estrone, estradiol, and estriol on hormone-responsive human breast cancer in long-term tissue culture. ( Bolan, G; Lippman, M; Monaco, ME, 1977) |
| "38 specimens of benign breast tissue from young women and 92 primary breast carcinomas were evaluated for tritiated thymidine ([3H]TdR) labeling index (TLI) by in vitro pulse labeling." | 3.65 | Tritiated thymidine labeling index of benign and malignant human breast epithelium. ( Bauer, WC; Meyer, JS, 1976) |
| "The in vitro effects of cortisol, estradiol, progesterone, and testosterone on the uptake of tritiated thymidine into the tumor cells of 25 women with primary or metastatic breast cancer were studied and compared with the objective clinical response to ablative endocrine surgery." | 3.65 | In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation. ( Burstein, NA; Carey, RW, 1974) |
| "In stage II breast cancer, progesterone receptor (PgR) content appears to be better than ER content in predicting disease-free and overall survival." | 2.37 | Steroid receptors and other prognostic factors in primary breast cancer. ( Clark, GM; McGuire, WL, 1988) |
| "However, in the case of breast and prostate cancer sera, TK 210 ELISA had higher sensitivity (59% and 44%) compared to [3H]-dThd phosphorylation assay (47% and 25%) at a specificity of 98%." | 1.72 | Analytical and clinical characterization of an optimized dual monoclonal sandwich ELISA for the quantification of thymidine kinase 1 (TK1) protein in human blood samples. ( J, O; Jagarlamudi, KK; L, S; M, Z; P, V; S, E, 2022) |
| "Palmitic acid was the main compound responsible for this apoptotic effect by a ceramide-independent mechanism that involved endoplasmic reticulum (ER)-stress with upregulation of CCAAT/-enhancer-binding protein homologous protein (CHOP)." | 1.39 | Palmitic acid and ergosta-7,22-dien-3-ol contribute to the apoptotic effect and cell cycle arrest of an extract from Marthasterias glacialis L. in neuroblastoma cells. ( Andrade, PB; Correia-da-Silva, G; Pereira, DM; Teixeira, N; Valentão, P, 2013) |
| " With MCF-7 cells on a collagen IV surface, the ranking of mitogens was maintained, but fold mitogenic responses and dynamic range and steepness of dose-response curves were increased." | 1.35 | MCF-7 human mammary adenocarcinoma cells exhibit augmented responses to human insulin on a collagen IV surface. ( Hansen, EW; Holm, GM; Jensen, MB; Kiehr, B; Listov-Saabye, N; Lundby, A; Oleksiewicz, MB; Svendsen, JE, 2009) |
| "Paclitaxel (PTX) is a widely used chemotherapy agent and may cause cell death by apoptosis subsequent to microtubule (MT) disruption." | 1.34 | Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity. ( Fernando, R; Foster, JS; Henley, D; Isbill, M; Wimalasena, J, 2007) |
| "Further, estrogen stimulates breast cancer MCF7 cell proliferation, whereas it has no effect on proliferation of periodontal ligament cells, probably reflecting cell type specific ER expression pattern in these two cell types." | 1.33 | Differential effects of estrogen on DNA synthesis in human periodontal ligament and breast cancer cells. ( Bratthall, G; Idvall, I; Johnsson, I; Jönsson, D; Nilsson, BO; Wahlin, A, 2005) |
| "Furthermore, breast cancer risks associated with the TS3'-UTR del6/del6 genotype were more evident in older women, postmenopausal subjects, individuals with a younger age at first-live birth and individuals with an older age at menarche." | 1.33 | Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis. ( Chen, F; Chen, W; Gao, J; Hu, Z; Jin, G; Liu, J; Qin, J; Shen, H; Tang, J; Wang, S; Wang, X; Wei, Q; Zhai, X, 2006) |
| " Therefore, we have investigated the effects of the orally bioavailable Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin (17-DMAG) on the radiosensitivity of human tumor cells in vitro and grown as tumor xenografts." | 1.32 | Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin. ( Brady, KJ; Bull, EE; Burgan, WE; Camphausen, K; Carter, DJ; Cerra, MA; Dote, H; Hollingshead, MG; Oswald, KA; Tofilon, PJ, 2004) |
| "The effects of glucose and leptin on breast cancer cell proliferation were evaluated by examining cell doubling time, DNA synthesis, levels of cell cycle related proteins, protein kinase C (PKC) isozyme expression, and peroxisome proliferator-activated receptor (PPAR) subtypes were determined following glucose exposure at normal (5." | 1.31 | Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-alpha and PPAR expression. ( Cooper, DR; Jamali, M; Kojima, T; Maruyama, T; Okumura, M; Sakuma, H; Yamamoto, M; Yasuda, K, 2002) |
| " We evaluated the dose-response relationship of ODD level to breast cancer risk, using quartiles of ODD." | 1.31 | Recruitment for a pilot case control study of oxidative DNA damage and breast cancer risk. ( Djuric, Z; Heilbrun, LK; Lababidi, S; Simon, MS; Stephens, D, 2000) |
| "To explore the role of Brn-3b in breast cancer, we established stable cell lines derived from the MCF7 human breast cancer cell line which had been transfected with Brn-3b sense or anti-sense constructs." | 1.31 | The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells. ( Budhram-Mahadeo, V; Dennis, JH; Latchman, DS, 2001) |
| "This cell line differs from many other breast cancer-derived cell lines in that E2 (1 nM) does not induce cell cycle progression, whereas the combination of submitogenic concentrations of IGF-I (2 ng/ml) and E2 does." | 1.31 | Synergistic proliferative action of insulin-like growth factor I and 17 beta-estradiol in MCF-7S breast tumor cells. ( Hamelers, IH; Steenbergh, PH; Sussenbach, JS; van Schaik, RF; van Teeffelen, HA, 2002) |
| "PTHrP is secreted by breast cancer cells in vivo and in vitro." | 1.31 | Intracrine PTHrP protects against serum starvation-induced apoptosis and regulates the cell cycle in MCF-7 breast cancer cells. ( Falzon, M; Shen, X; Tovar Sepulveda, VA, 2002) |
| "Study of leptin effects on human breast cancer cells growth was performed by [3H]-thymidine incorporation method and colorimetric MTT assay." | 1.31 | Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line. ( Djiane, J; Gourdou, I; Laud, K; Pessemesse, L; Peyrat, JP, 2002) |
| "Obesity is a risk factor of breast cancers." | 1.31 | Leptin mediates a proliferative response in human MCF7 breast cancer cells. ( Dieudonne, MN; Giudicelli, Y; Leneveu, MC; Machinal-Quelin, F; Pecquery, R; Serazin-Leroy, V, 2002) |
| "In 3,800 node-negative breast cancers recruited between 1972 and 1991, the consistency of information provided by the 3H-thymidine labelling index (TLI), in terms of basic relations with other clinico-pathological and biological variables and clinical predictivity, was evaluated using a combined analysis of results previously published by our group for distinct series of patients." | 1.30 | Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index. ( Daidone, MG; Leutner, M; Luisi, A; Mastore, M; Salvadori, B; Silvestrini, R, 1997) |
| "LTB4 or LTD4 inhibits MCF-7 breast cancer cell growth." | 1.30 | Influence of leukotrienes on in vitro growth of human mammary carcinoma cell line MCF-7. ( Hafner, J; Köhn, FM; Przylipiak, A; Przylipiak, J; Rabe, T; Runnebaum, B, 1998) |
| "Acetaminophen is a commonly used analgesic/antipyretic that also contains a p-phenol." | 1.30 | Acetaminophen alters estrogenic responses in vitro: stimulation of DNA synthesis in estrogen-responsive human breast cancer cells. ( Harnagea-Theophilus, E; Miller, MR, 1998) |
| "In half of the human breast cancers investigated, tumor-derived fibroblasts stimulated tumor-derived epithelial cell proliferation." | 1.29 | Role of tumor-derived fibroblasts in the growth of primary cultures of human breast-cancer cells: effects of epidermal growth factor and the somatostatin analogue octreotide. ( Hofland, LJ; Lamberts, SW; Sprij, DM; van der Burg, B; van Eijck, CH; van Koetsveld, PM, 1995) |
| "Gossypol is a polyphenolic aldehyde occurring naturally in cottonseed that produces antisteroidogenic activity in vivo, has been extensively investigated as a male contraceptive agent, and has demonstrated anticancer activity." | 1.29 | Antiproliferative activity of gossypol and gossypolone on human breast cancer cells. ( Brueggemeier, RW; Chang, CJ; Gilbert, NE; Lin, YC; O'Reilly, JE, 1995) |
| "The human MCF-7 breast cancer cell line was transfected with the dThdPase cDNA and expressed a 45 kDa protein that was detected with anti-dThdPase antibody." | 1.29 | Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase. ( Bicknell, R; Harris, AL; Moghaddam, A; Patterson, AV; Stratford, IJ; Talbot, DC; Zhang, H, 1995) |
| "MCF7 human breast cancer cells are known to be mitogenically responsive to insulin-like growth factors and estrogens, to secrete several IGFBPs, including BP-2, BP-4 and BP-5, and to be growth inhibited by antiestrogens." | 1.29 | Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned media. ( Pollak, MN; Pratt, SE, 1993) |
| "The role of Raf-1 kinase in breast cancer has not been studied." | 1.29 | Raf-1 protein expression in human breast cancer cells. ( Callans, LS; Jardines, L; Khandelwal, M; Naama, H; Plotkin, R, 1995) |
| "One hundred thirty-two breast carcinomas were studied retrospectively using formalin fixed, paraffin embedded archival tissues on which S-LI and S-flow had been obtained originally." | 1.29 | Assessment of proliferating cell nuclear antigen (PCNA) in breast cancer using anti-PCNA PC10 and 19A2: correlation with 5-bromo-2'-deoxyuridine or tritiated thymidine labeling and flow cytometric analysis. ( He, W; Hughes, J; Koehm, S; Meyer, JS; Scrivner, DL, 1994) |
| "Hormonal management of breast cancer is confounded by an almost inevitable progression of cell growth from a steroid-regulated to a steroid-autonomous state." | 1.29 | Alterations in transforming growth factor-alpha and -beta production and cell responsiveness during the progression of MCF-7 human breast cancer cells to estrogen-autonomous growth. ( Herman, ME; Katzenellenbogen, BS, 1994) |
| "While lymphocytes of breast cancer patients (n = 21) and women with benign breast disease (n = 19) incubated with p43 as well as with anti-p43 antibody did not show any difference in terms of incorporation of [3H]thymidine, activation of lymphocytes by addition of Con A was significantly inhibited after addition of p43 antigen in breast cancer patients compared to women with benign breast disease (P = 0." | 1.29 | Downregulation of lymphocyte mitogenesis by breast cancer-associated p43. ( Ausch, C; Moroz, C; Reiner, G; Reinerova, M; Rosen, HR; Schiessel, R; Svec, J; Tüchler, H, 1994) |
| "A human breast cancer cell line (MCF7) was also growth-inhibited by 10(-5) M thymidine but a murine lymphoma cell line (K36) was not." | 1.29 | Selective antiproliferative effects of thymidine. ( Chung, MC; Kon, OL; Ooi, SO; Sim, KY, 1993) |
| "MCF-7 breast cancer cells had relatively higher levels of non-protein thiols, oxidized glutathione (GSSG) reductase, catalase, and superoxide dismutase than did the MCF-10A line of immortalized, but not transformed, human breast epithelial cells." | 1.29 | Toxicity, single-strand breaks, and 5-hydroxymethyl-2'-deoxyuridine formation in human breast epithelial cells treated with hydrogen peroxide. ( Djuric, Z; Everett, CK; Luongo, DA, 1993) |
| "Human endometrial and breast carcinoma cell lines were examined for aromatase activity and the effects of sex steroids (estradiol and testosterone) on DNA synthesis." | 1.29 | Aromatase activity and the effect of estradiol and testosterone on DNA synthesis in endometrial carcinoma cell lines. ( Nakamura, J; Sasaki, H; Tada, A; Terashima, Y; Yoshihama, M, 1993) |
| "The LI of 234 consecutive breast carcinomas were measured with TT as was a subsequent series of 450 cases with BrdU, both by incubation in vitro." | 1.29 | Bromodeoxyuridine labeling for S-phase measurement in breast carcinoma. ( Higa, E; Hughes, JM; Koehm, SL; Lagos, JA; Manes, JL; Meyer, JS; Wittliff, JL, 1993) |
| "Treatment of Hs578T breast cancer cells with long chain saturated fatty acids (0." | 1.29 | Stearate inhibition of breast cancer cell proliferation. A mechanism involving epidermal growth factor receptor and G-proteins. ( Hardy, RW; Jo, H; McDonald, JM; Wickramasinghe, NS, 1996) |
| "In contrast, ER(-) breast cancer cell lines were resistant to IL-6-mediated growth inhibition." | 1.29 | Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines. ( Chiu, JJ; Cowan, KH; Sgagias, MK, 1996) |
| "The T47D human breast cancer cells used in this study express relative high levels of the progesterone receptor (637 +/- 118 fmol/mg protein) and lower levels of the estrogen and aryl hydrocarbon (Ah) receptors (81 +/- 3." | 1.28 | Growth inhibitory and antimitogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in T47D human breast cancer cells. ( Fernandez, P; Safe, S, 1992) |
| "Paradoxically, primary human breast carcinoma cells are difficult to establish in culture: most outgrowths arise from the normal tissue surrounding the tumor." | 1.28 | Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells. ( Bissell, MJ; Howlett, AR; Petersen, OW; Rønnov-Jessen, L, 1992) |
| "In contrast, estrogen-independent human breast cancer cells do not activate this programmed cell death pathway following estrogen ablation." | 1.28 | Programmed cell death in an estrogen-independent human breast cancer cell line, MDA-MB-468. ( Armstrong, DK; Davidson, NE; Isaacs, JT; Ottaviano, YL, 1992) |
| "Human breast cancer cells have been recently reported to produce endothelin (ET) 1." | 1.28 | Bombesin and glucocorticoids stimulate human breast cancer cells to produce endothelin, a paracrine mitogen for breast stromal cells. ( Patel, KV; Schrey, MP; Tezapsidis, N, 1992) |
| "The insulin receptors in the breast cancer cell lines were functional: (a) In all 4 cell lines, high-affinity insulin-binding sites were detected, and, in concert with the insulin receptor radioimmunoassay data, binding capacity was highest in MCF-7 and then in ZR-75-1 cells." | 1.28 | Insulin receptor expression and function in human breast cancer cell lines. ( Belfiore, A; Damante, G; Giorgino, F; Goldfine, ID; Milazzo, G; Stampfer, MR; Sung, C; Vigneri, R, 1992) |
| "In the breast cancer patients, TLI did not significantly correlate to tumor size, the presence of axillary lymph node metastasis or pathologic nuclear grading." | 1.28 | Thymidine labeling index in breast tumors. ( Chi, HS; Jung, HJ; Kim, BR; Lee, HD; Lee, KS; Soh, EY; Song, KS, 1990) |
| "14 patients with advanced breast cancer were treated parenterally with Iscador, an extract of Viscum album (mistletoe)." | 1.28 | Improvement of DNA repair in lymphocytes of breast cancer patients treated with Viscum album extract (Iscador). ( Hajto, T; Hostanska, K; Kovacs, E, 1991) |
| "We recommend multiple sampling of large breast carcinomas and analysis of axillary metastases for study of tumor markers." | 1.28 | Regional heterogeneity in breast carcinoma: thymidine labelling index, steroid hormone receptors, DNA ploidy. ( Meyer, JS; Wittliff, JL, 1991) |
| "The variable labeling indices of breast cancer express the different growth rate of the tumors." | 1.28 | [Cell kinetic investigations in fibrocystic mastopathies and invasive breast carcinomas]. ( Kunz, J, 1990) |
| "The effects of pimozide on breast cancer cell growth were not limited to the MCF-7 cell line." | 1.28 | Inhibition of human breast cancer cell proliferation in tissue culture by the neuroleptic agents pimozide and thioridazine. ( Kirkwood, KL; Lantz, TK; Lewine, MA; Peterson, VA; Strobl, JS; Worley, JF, 1990) |
| "Mitomycin C (MMC) was combined with 2." | 1.27 | Combined cytotoxic and endocrine therapy for human breast carcinoma (Br-10) serially transplanted into nude mice. ( Abe, O; Asanuma, F; Enomoto, K; Ishibiki, K; Koh, J; Kubota, T; Kubouchi, K, 1984) |
| "The results for solid intraductal carcinoma, which is a less well defined and more heterogeneous entity, were intermediate (median 2." | 1.27 | Cell kinetics of histologic variants of in situ breast carcinoma. ( Meyer, JS, 1986) |
| "We report that human breast cancer cells secrete a growth factor that is biologically and immunologically similar to platelet-derived growth factor (PDGF)." | 1.27 | Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines. ( Antoniades, HN; Bronzert, DA; Davidson, N; Dickson, RB; Kasid, A; Lippman, ME; Pantazis, P, 1987) |
| "Mean TLI for the breast carcinomas was 4." | 1.27 | Thymidine labeling index, flow cytometric S-phase measurement, and DNA index in human tumors. Comparisons and correlations. ( Coplin, MD; Meyer, JS, 1988) |
| "The responsiveness of the human mammary carcinoma cell line MCF-7 to estradiol and tamoxifen treatment has been studied in different culture conditions." | 1.27 | Interaction of estradiol and high density lipoproteins on proliferation of the human breast cancer cell line MCF-7 adapted to grow in serum free conditions. ( Bayard, F; David, JF; Faye, JC; Jozan, S; Tauber, JP; Tournier, JF, 1985) |
| "The proliferative rate of breast carcinoma appears to be an important determinant of morphologic patterns." | 1.27 | Breast carcinoma cell kinetics, morphology, stage, and host characteristics. A thymidine labeling study. ( Babcock, DS; McDivitt, RW; Meyer, JS; Prey, MU, 1986) |
| "Sixty-four patients with breast cancer were the subjects studied." | 1.27 | Significance of the Tritiated Thymidine Labeling Index in breast cancers. ( Akagi, M; Araki, K; Kimura, M; Nishimura, R; Sakamoto, K, 1985) |
| "Phomopsin is a mycotoxin known to be carcinogenic." | 1.27 | Influence of phomopsin and ivalin on steroid-hormone binding and growth of MCF-7 human breast cancer cells. ( Lewko, WM; van Aswegen, CH; Wittliff, JL, 1985) |
| "EGF had no effect on another human breast cancer cell line, the MDA-231." | 1.26 | Epidermal growth factor stimulation of human breast cancer cells in culture. ( Hamilton, B; Livingston, RB; Osborne, CK; Titus, G, 1980) |
| "DNA control values of different tumors (without drug) varying in a very high degree are analyzed and correspond to drug response rate in vitro." | 1.26 | [Pretherapeutical testing of antineoplastic drugs in vitro (author's transl)]. ( Nissen, E; Peek, U; Projan, A; Tanneberger, S, 1982) |
| "[3H]-Thymidine was administered in vivo." | 1.26 | Estrogen receptor heterogeneity and the relationship between estrogen receptor and the tritiated thymidine labeling index in human breast cancer. ( Moran, R; Muller, RE; Straus, MJ; Wotiz, HH, 1982) |
| "In vitro cultures of breast cancer tissue demonstrate that some tumours are hormone-sensitive and others hormone-insensitive, but it cannot be predicted whether cell proliferation is stimulated or inhibited by hormone treatment." | 1.26 | Short-term culture of human breast cancer: in vitro effects of hormones related to patient response. ( Andersen, J; Bichel, P; Poulsen, HS, 1982) |
| "The HFC's from a human mammary carcinoma line, BT-20, contained very low levels of mitogenic activity and plasminogen activator." | 1.26 | Mitogenic activity and plasminogen activator in harvest fluid concentrates from mammary cells in culture. ( Cheng, CY; Howard, EF; Howard, JS, 1980) |
| "The surgical specimens of breast tumors were incubated in vitro with tritiated thymidine and autoradiographies were performed." | 1.26 | Kinetic parameters and the course of the disease in breast cancer. ( Chavaudra, N; Contesso, G; Gioanni, J; Malaise, EP; Pejovic, MJ; Renaud, A; Tubiana, M, 1981) |
| "The cell proliferation pattern in human breast cancer has been studied in eight patients in vivo using intravenously administered 3HTdR as a pulse and as a continous label." | 1.26 | The proliferative patterns of human breast cancer cells in vivo. ( Hoffman, J; Post, J; Sklarew, RJ, 1977) |
| "Twenty biopsy specimens of benign human breast tumors obtained from 20 patients were processed into small slices and individually cultured for 2 days in Medium 199." | 1.26 | Stimulation of DNA synthesis by human placental lactogen or insulin in organ cultures of benign human breast tumors. ( McManus, MJ; Welsch, CW, 1977) |
| "The mean LI for 39 human mammary carcinomas was 3." | 1.25 | In vitro determination of tritiated thymidine labeling index (LI). Evaluation of a method utilizing hyperbaric oxygen and observations on the LI of human mammary carcinoma. ( Bauer, WC; Meyer, JS, 1975) |
| "Primary tumours and metastases of the same patient frequently showed different sensitivity." | 1.25 | [In-vitro testing of the sensitivity of mammary carcinoma cells to cytostatic drugs (author's transl)]. ( Bastert, G; Gerner, R; Leppien, G; Michel, RT; Nord, D; Schmidt-Matthiesen, H, 1975) |
| "Serum from cancer patients impaired the response of normal lymphocytes." | 1.25 | The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients. ( Kumar, S; Taylor, G, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 168 (48.55) | 18.7374 |
| 1990's | 104 (30.06) | 18.2507 |
| 2000's | 64 (18.50) | 29.6817 |
| 2010's | 9 (2.60) | 24.3611 |
| 2020's | 1 (0.29) | 2.80 |
| Authors | Studies |
|---|---|
| Jagarlamudi, KK | 1 |
| L, S | 1 |
| M, Z | 1 |
| J, O | 1 |
| P, V | 1 |
| S, E | 1 |
| Sadowska, A | 1 |
| Prokopiuk, S | 1 |
| Miltyk, W | 2 |
| Surażyński, A | 1 |
| Konończuk, J | 1 |
| Sawicka, D | 1 |
| Car, H | 1 |
| Pestana, D | 1 |
| Teixeira, D | 1 |
| Faria, A | 1 |
| Domingues, V | 1 |
| Monteiro, R | 1 |
| Calhau, C | 1 |
| Pereira, DM | 1 |
| Correia-da-Silva, G | 1 |
| Valentão, P | 1 |
| Teixeira, N | 1 |
| Andrade, PB | 1 |
| Vande Voorde, J | 1 |
| Sabuncuoğlu, S | 1 |
| Noppen, S | 1 |
| Hofer, A | 1 |
| Ranjbarian, F | 1 |
| Fieuws, S | 1 |
| Balzarini, J | 2 |
| Liekens, S | 1 |
| Achari, C | 1 |
| Winslow, S | 1 |
| Ceder, Y | 1 |
| Larsson, C | 1 |
| Borland, KM | 1 |
| AbdulSalam, SF | 1 |
| Solivio, MJ | 1 |
| Burke, MP | 1 |
| Wolfkiel, PR | 1 |
| Lawson, SM | 1 |
| Stockman, CA | 1 |
| Andersen, JM | 1 |
| Smith, S | 1 |
| Tolstolutskaya, JN | 1 |
| Gurjar, PN | 1 |
| Bercz, AP | 1 |
| Merino, EJ | 1 |
| Litosh, VA | 1 |
| Direcks, WG | 1 |
| Berndsen, SC | 1 |
| Proost, N | 1 |
| Peters, GJ | 1 |
| Spreeuwenberg, MD | 1 |
| Lammertsma, AA | 1 |
| Molthoff, CF | 1 |
| Wilson, PM | 1 |
| Fazzone, W | 1 |
| LaBonte, MJ | 1 |
| Deng, J | 1 |
| Neamati, N | 1 |
| Ladner, RD | 1 |
| Radpour, R | 1 |
| Haghighi, MM | 1 |
| Fan, AX | 1 |
| Torbati, PM | 1 |
| Hahn, S | 1 |
| Holzgreve, W | 1 |
| Zhong, XY | 1 |
| Cho, SH | 1 |
| Choi, MH | 1 |
| Lee, WY | 1 |
| Chung, BC | 1 |
| Dittmann, H | 1 |
| Jusufoska, A | 1 |
| Dohmen, BM | 1 |
| Smyczek-Gargya, B | 1 |
| Fersis, N | 1 |
| Pritzkow, M | 1 |
| Kehlbach, R | 1 |
| Vonthein, R | 1 |
| Machulla, HJ | 1 |
| Bares, R | 1 |
| Listov-Saabye, N | 1 |
| Jensen, MB | 1 |
| Kiehr, B | 1 |
| Hansen, EW | 1 |
| Svendsen, JE | 1 |
| Lundby, A | 1 |
| Holm, GM | 1 |
| Oleksiewicz, MB | 1 |
| Bielawski, K | 4 |
| Bielawska, A | 4 |
| Poplawska, B | 1 |
| Zhang, HY | 1 |
| Liu, ZG | 1 |
| Zhang, Z | 1 |
| Gong, HY | 1 |
| Golubovskaya, VM | 1 |
| Palma, NL | 1 |
| Zheng, M | 1 |
| Ho, B | 1 |
| Magis, A | 1 |
| Ostrov, D | 1 |
| Cance, WG | 1 |
| Corominas-Faja, B | 1 |
| Quirantes-Piné, R | 1 |
| Oliveras-Ferraros, C | 1 |
| Vazquez-Martin, A | 1 |
| Cufí, S | 1 |
| Martin-Castillo, B | 1 |
| Micol, V | 1 |
| Joven, J | 1 |
| Segura-Carretero, A | 1 |
| Menendez, JA | 1 |
| Sauer, G | 1 |
| Kafka, A | 1 |
| Grundmann, R | 1 |
| Kreienberg, R | 1 |
| Zeillinger, R | 1 |
| Deissler, H | 1 |
| Chan, RY | 1 |
| Chen, WF | 1 |
| Dong, A | 1 |
| Guo, D | 1 |
| Wong, MS | 1 |
| Okumura, M | 1 |
| Yamamoto, M | 1 |
| Sakuma, H | 1 |
| Kojima, T | 1 |
| Maruyama, T | 1 |
| Jamali, M | 1 |
| Cooper, DR | 1 |
| Yasuda, K | 1 |
| Black, CA | 1 |
| Ucci, JW | 1 |
| Vorpagel, JS | 1 |
| Mauck, MC | 1 |
| Fenlon, EE | 1 |
| Ingólfsdóttir, K | 1 |
| Gudmundsdóttir, GF | 1 |
| Ogmundsdóttir, HM | 1 |
| Paulus, K | 1 |
| Haraldsdóttir, S | 1 |
| Kristinsson, H | 1 |
| Bauer, R | 1 |
| Molino, A | 1 |
| Pedersini, R | 1 |
| Micciolo, R | 1 |
| Frisinghelli, M | 1 |
| Giovannini, M | 1 |
| Pavarana, M | 1 |
| Nortilli, R | 1 |
| Santo, A | 1 |
| Manno, P | 1 |
| Padovani, M | 1 |
| Piubello, Q | 1 |
| Cetto, GL | 1 |
| Butt, AJ | 2 |
| Dickson, KA | 1 |
| McDougall, F | 1 |
| Baxter, RC | 2 |
| Swamy, N | 1 |
| Persons, KS | 1 |
| Chen, TC | 1 |
| Ray, R | 1 |
| Ríhová, B | 1 |
| Strohalm, J | 1 |
| Prausová, J | 1 |
| Kubácková, K | 1 |
| Jelínková, M | 1 |
| Rozprimová, L | 1 |
| Sírová, M | 1 |
| Plocová, D | 1 |
| Etrych, T | 1 |
| Subr, V | 1 |
| Mrkvan, T | 1 |
| Kovár, M | 1 |
| Ulbrich, K | 1 |
| MENDELSOHN, ML | 4 |
| SKY-PECK, HH | 2 |
| HENDRICKSON, FR | 1 |
| KLIGERMAN, MM | 1 |
| HEIDENREICH, WF | 1 |
| GREENE, S | 1 |
| STAROSCIK, RN | 1 |
| JENKINS, WH | 1 |
| Conover, CA | 1 |
| Khosla, S | 1 |
| Montgomery, KG | 1 |
| Liu, MC | 1 |
| Eccles, DM | 1 |
| Campbell, IG | 1 |
| Bilir, A | 2 |
| Ozmen, V | 2 |
| Kecer, M | 2 |
| Eralp, Y | 1 |
| Cabioglu, N | 2 |
| Ahishali, B | 1 |
| Agizhali, B | 1 |
| Camlica, H | 1 |
| Aydiner, A | 2 |
| Mujoomdar, M | 1 |
| Bennett, A | 1 |
| Hoskin, D | 1 |
| Blay, J | 1 |
| Czeczuga-Semeniuk, E | 2 |
| Anchim, T | 3 |
| Dziecioł, J | 2 |
| Dabrowska, M | 2 |
| Wołczyński, S | 1 |
| Chan, KK | 1 |
| Chan, JY | 1 |
| Chung, KK | 1 |
| Fung, KP | 1 |
| Bull, EE | 1 |
| Dote, H | 1 |
| Brady, KJ | 1 |
| Burgan, WE | 1 |
| Carter, DJ | 1 |
| Cerra, MA | 1 |
| Oswald, KA | 1 |
| Hollingshead, MG | 1 |
| Camphausen, K | 1 |
| Tofilon, PJ | 1 |
| Meyer, JS | 23 |
| Alvarez, C | 1 |
| Milikowski, C | 1 |
| Olson, N | 1 |
| Russo, I | 1 |
| Russo, J | 1 |
| Glass, A | 1 |
| Zehnbauer, BA | 1 |
| Lister, K | 1 |
| Parwaresch, R | 1 |
| Jönsson, D | 1 |
| Wahlin, A | 1 |
| Idvall, I | 1 |
| Johnsson, I | 1 |
| Bratthall, G | 1 |
| Nilsson, BO | 1 |
| Bonofiglio, D | 1 |
| Gabriele, S | 1 |
| Aquila, S | 1 |
| Catalano, S | 1 |
| Gentile, M | 1 |
| Middea, E | 1 |
| Giordano, F | 1 |
| Andò, S | 1 |
| Coinu, R | 1 |
| Galleri, G | 1 |
| Pippia, P | 1 |
| Tilocca, MG | 1 |
| Meloni, M | 1 |
| Covelli, B | 1 |
| Chiaviello, A | 1 |
| Palumbo, G | 1 |
| Vázquez, SM | 1 |
| Mladovan, AG | 1 |
| Pérez, C | 1 |
| Bruzzone, A | 1 |
| Baldi, A | 1 |
| Lüthy, IA | 1 |
| Zhai, X | 1 |
| Gao, J | 1 |
| Hu, Z | 1 |
| Tang, J | 1 |
| Qin, J | 1 |
| Wang, S | 1 |
| Wang, X | 2 |
| Jin, G | 1 |
| Liu, J | 1 |
| Chen, W | 1 |
| Chen, F | 1 |
| Wei, Q | 1 |
| Shen, H | 1 |
| Sosnowska, K | 1 |
| Winnicka, K | 1 |
| Pałka, J | 2 |
| Pacher, M | 1 |
| Seewald, MJ | 1 |
| Mikula, M | 1 |
| Oehler, S | 1 |
| Mogg, M | 1 |
| Vinatzer, U | 1 |
| Eger, A | 1 |
| Schweifer, N | 1 |
| Varecka, R | 1 |
| Sommergruber, W | 1 |
| Mikulits, W | 1 |
| Schreiber, M | 1 |
| Henley, D | 1 |
| Isbill, M | 1 |
| Fernando, R | 1 |
| Foster, JS | 1 |
| Wimalasena, J | 1 |
| Gao, L | 1 |
| Yu, S | 1 |
| Wu, Y | 1 |
| Shan, B | 1 |
| Yam, J | 1 |
| Schaab, A | 1 |
| Kreuter, M | 1 |
| Drewe, J | 1 |
| Peter, HH | 1 |
| Wrba, H | 1 |
| Rabes, H | 1 |
| Marth, C | 1 |
| Mayer, I | 1 |
| Daxenbichler, G | 1 |
| Major, PP | 1 |
| Egan, E | 1 |
| Herrick, D | 1 |
| Kufe, DW | 2 |
| Delinassios, JG | 1 |
| Kottaridis, SD | 1 |
| Nissen, E | 3 |
| Tanneberger, S | 2 |
| Weiss, H | 2 |
| Bender, E | 1 |
| McDivitt, RW | 5 |
| Stone, KR | 3 |
| Huff, KK | 1 |
| Lippman, ME | 9 |
| Kubota, T | 1 |
| Kubouchi, K | 1 |
| Koh, J | 1 |
| Asanuma, F | 1 |
| Enomoto, K | 1 |
| Ishibiki, K | 1 |
| Abe, O | 1 |
| Vietti Ramus, G | 1 |
| Cesano, L | 1 |
| Barbalonga, A | 1 |
| Jozan, S | 3 |
| Mirouze, A | 2 |
| Gay, AG | 1 |
| Marques, B | 2 |
| David, JF | 3 |
| Smallwood, JA | 2 |
| Cooper, A | 2 |
| Taylor, I | 2 |
| Safa, AR | 1 |
| Chegini, N | 1 |
| Tseng, MT | 1 |
| Morgan, GR | 1 |
| Kirkham, N | 1 |
| Williams, CJ | 1 |
| Whitehouse, JM | 1 |
| Jakesz, R | 1 |
| Smith, CA | 1 |
| Aitken, S | 2 |
| Huff, K | 3 |
| Schuette, W | 1 |
| Shackney, S | 1 |
| Lippman, M | 3 |
| Tubiana, M | 3 |
| Pejovic, MH | 1 |
| Chavaudra, N | 2 |
| Contesso, G | 2 |
| Malaise, EP | 2 |
| Schönenberger, H | 2 |
| Wappes, B | 1 |
| Jennerwein, M | 1 |
| Berger, M | 1 |
| von Angerer, E | 1 |
| Egginger, G | 1 |
| Kranzfelder, G | 1 |
| Bernhauer, H | 1 |
| Page, MJ | 2 |
| Field, JK | 2 |
| Everett, NP | 1 |
| Green, CD | 2 |
| Friedman, E | 1 |
| McCrate, MM | 1 |
| Bauer, WC | 4 |
| Osborne, CK | 3 |
| Hamilton, B | 1 |
| Titus, G | 1 |
| Livingston, RB | 4 |
| Coosen, R | 1 |
| de Jong, PW | 1 |
| Schwarz, F | 1 |
| Aitken, SC | 2 |
| Projan, A | 1 |
| Peek, U | 1 |
| Straus, MJ | 1 |
| Moran, R | 1 |
| Muller, RE | 1 |
| Wotiz, HH | 1 |
| Connor, RE | 1 |
| Poulsen, HS | 1 |
| Bichel, P | 1 |
| Andersen, J | 1 |
| DiSorbo, DM | 1 |
| Litwack, G | 1 |
| Elson, DL | 1 |
| Von Hoff, DD | 1 |
| Howard, EF | 1 |
| Cheng, CY | 1 |
| Howard, JS | 1 |
| Van den Berg, HW | 1 |
| Clarke, R | 1 |
| Murphy, RF | 1 |
| Pejovic, MJ | 1 |
| Renaud, A | 1 |
| Gioanni, J | 6 |
| Yu, WC | 1 |
| Leung, BS | 3 |
| Gao, YL | 1 |
| Nordenskjöld, B | 1 |
| Skoog, L | 1 |
| Wallgren, A | 1 |
| Silfverswärd, C | 1 |
| Gustafsson, S | 1 |
| Ljung, BM | 2 |
| Westerberg, H | 1 |
| Gustafsson, JA | 1 |
| Wrange, O | 1 |
| Potter, AH | 2 |
| Qureshi, S | 1 |
| Cooke, T | 1 |
| George, WD | 3 |
| Griffiths, K | 1 |
| Allegra, JC | 1 |
| Bronzert, DA | 2 |
| Monaco, ME | 3 |
| Pinkus, L | 1 |
| von Matthiessen, H | 1 |
| Koldovsky, U | 1 |
| Feldhammer, B | 1 |
| Pratt, SE | 2 |
| Pollak, MN | 2 |
| Hofland, LJ | 1 |
| van der Burg, B | 2 |
| van Eijck, CH | 1 |
| Sprij, DM | 1 |
| van Koetsveld, PM | 1 |
| Lamberts, SW | 1 |
| Benini, E | 2 |
| Silvestrini, R | 16 |
| Daidone, MG | 13 |
| Canova, S | 1 |
| Bani, D | 1 |
| Masini, E | 1 |
| Bello, MG | 1 |
| Bigazzi, M | 1 |
| Sacchi, TB | 1 |
| Gilbert, NE | 1 |
| O'Reilly, JE | 1 |
| Chang, CJ | 2 |
| Lin, YC | 2 |
| Brueggemeier, RW | 2 |
| Noguchi, M | 2 |
| Earashi, M | 1 |
| Miyazaki, I | 2 |
| Tanaka, M | 1 |
| Sasaki, T | 2 |
| Paradiso, A | 2 |
| Mangia, A | 2 |
| Barletta, A | 1 |
| Fusilli, S | 1 |
| Marzullo, F | 1 |
| Schittulli, F | 2 |
| De Lena, M | 1 |
| Patterson, AV | 2 |
| Zhang, H | 1 |
| Moghaddam, A | 1 |
| Bicknell, R | 1 |
| Talbot, DC | 2 |
| Stratford, IJ | 2 |
| Harris, AL | 3 |
| Rostagno, P | 1 |
| Birtwisle, I | 1 |
| Ettore, F | 2 |
| Courdi, A | 3 |
| Namer, M | 5 |
| Caldani, C | 1 |
| Luisi, A | 3 |
| Mastore, M | 5 |
| Veneroni, S | 1 |
| Brambilla, C | 1 |
| Ferrari, L | 2 |
| Greco, M | 2 |
| Andreola, S | 1 |
| Vintermyr, OK | 1 |
| Bøe, R | 1 |
| Brustugun, OT | 1 |
| Maronde, E | 1 |
| Aakvaag, A | 1 |
| Døskeland, SO | 1 |
| Callans, LS | 1 |
| Naama, H | 1 |
| Khandelwal, M | 1 |
| Plotkin, R | 1 |
| Jardines, L | 1 |
| Gardin, G | 2 |
| Alama, A | 6 |
| Rosso, R | 3 |
| Campora, E | 1 |
| Repetto, L | 1 |
| Pronzato, P | 2 |
| Merlini, L | 1 |
| Naso, C | 1 |
| Camoriano, A | 1 |
| Meazza, R | 2 |
| He, W | 1 |
| Scrivner, DL | 1 |
| Koehm, S | 1 |
| Hughes, J | 1 |
| Herman, ME | 1 |
| Katzenellenbogen, BS | 1 |
| Thomas, T | 1 |
| Thomas, TJ | 1 |
| Bisail, M | 1 |
| Nieddu, S | 1 |
| Sarobba, MG | 1 |
| Sanna, G | 1 |
| Milia, V | 1 |
| Ghì, MG | 1 |
| Farris, A | 1 |
| Rosen, HR | 1 |
| Ausch, C | 1 |
| Reiner, G | 1 |
| Reinerova, M | 1 |
| Svec, J | 1 |
| Tüchler, H | 1 |
| Schiessel, R | 1 |
| Moroz, C | 1 |
| Galimberti, S | 1 |
| Bianchi, F | 1 |
| Bernardini, N | 1 |
| Mattii, L | 1 |
| Dolfi, A | 1 |
| Lupetti, M | 1 |
| Petrini, M | 1 |
| Tillotson, JK | 1 |
| Upadhyaya, P | 1 |
| Ronai, Z | 1 |
| Hu, YF | 1 |
| Amadori, D | 6 |
| Volpi, A | 5 |
| Callea, A | 1 |
| Amaducci, L | 2 |
| Morgagni, S | 1 |
| Magni, E | 1 |
| Nanni, O | 4 |
| Ooi, SO | 1 |
| Sim, KY | 1 |
| Chung, MC | 1 |
| Kon, OL | 1 |
| Djuric, Z | 4 |
| Everett, CK | 1 |
| Luongo, DA | 2 |
| Pusztai, L | 1 |
| Lewis, CE | 1 |
| McGee, JO | 1 |
| Yu, L | 1 |
| Fernig, DG | 1 |
| Smith, JA | 1 |
| Milton, JD | 1 |
| Rhodes, JM | 1 |
| Del Bino, G | 1 |
| Di Fronzo, G | 5 |
| Boracchi, P | 2 |
| Tada, A | 1 |
| Sasaki, H | 1 |
| Nakamura, J | 1 |
| Yoshihama, M | 1 |
| Terashima, Y | 1 |
| Koehm, SL | 1 |
| Hughes, JM | 1 |
| Higa, E | 1 |
| Wittliff, JL | 3 |
| Lagos, JA | 1 |
| Manes, JL | 1 |
| Barbieri, F | 1 |
| Biassoni, R | 1 |
| Mazzei, M | 1 |
| Nicolin, A | 4 |
| Coradini, D | 2 |
| Squicciarini, P | 2 |
| Salvadori, B | 5 |
| Veronesi, U | 1 |
| Heilbrun, LK | 3 |
| Simon, MS | 3 |
| Smith, D | 1 |
| LoRusso, PM | 1 |
| Martino, S | 1 |
| Cos, S | 2 |
| Recio, J | 1 |
| Sánchez-Barceló, EJ | 2 |
| Collecchi, P | 1 |
| Giannessi, PG | 1 |
| Baldini, E | 1 |
| Naccarato, AG | 1 |
| Passoni, A | 1 |
| Bevilacqua, G | 1 |
| Conte, PF | 5 |
| Fernández, F | 1 |
| Chopra, S | 1 |
| Wallace, HM | 1 |
| Wickramasinghe, NS | 1 |
| Jo, H | 1 |
| McDonald, JM | 1 |
| Hardy, RW | 1 |
| Leutner, M | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase I, Open-Label, Non-Randomized, Dose-Escalating Safety, Tolerability and Pharmacokinetic Study of TAS-114 in Combination With S-1 in Patients With Advanced Solid Tumors[NCT02454062] | Phase 1 | 120 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| Breast Cancer and Insulin Resistance: Implications for Preventive Counseling in Familial and Sporadic Cases[NCT00304941] | 25 participants (Actual) | Observational | 2006-03-14 | Completed | |||
| Phase II Safety Study of Palbociclib in Combination With Letrozole or Fulvestrant in African American Women With Hormone Receptor Positive HER2 Negative Advanced Breast Cancer[NCT02692755] | Phase 2/Phase 3 | 35 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Clinical Benefit Rate (CBR), for those with evaluable disease, defined as the percentage of patients who achieved complete response, partial response and stable disease. RECIST 1.1 was used as the standard way to measure response to treatment. The mean (SD) of specific metabolites were calculated at each time point and graphically assess these measures over time with clinical response and hematological toxicity. The mean change in these variables from baseline to each follow-up point was be calculated. Generalized linear model was utilized for the correlative analysis of clinical response and hematologic events. (NCT02692755)
Timeframe: 24 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Single ARM | 23 |
Number of patients who required dose delays in palbociclib attributed to neutropenia. (NCT02692755)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Single ARM | 17 |
Number of patients who required dose reductions in palbociclib therapy (NCT02692755)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Single ARM | 13 |
"For study purpose febrile neutropenia will be defined according to the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) v4.0: ANC less than 1000/mm3 with a single temperature of >38.3 degrees Celsius (101 degrees Fahrenheit) or a sustained temperature of 38 degrees Celsius (100.4 degrees Fahrenheit) for more than one hour.~Planned oncology therapy is defined as completion of one year of therapy for advanced breast cancer in the absence of disease progression or cessation of study drug due to progressive disease or non-hematological toxicity." (NCT02692755)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Palbociclib + Letrozole or Fulvestrant | 35 |
10 reviews available for thymidine and Breast Cancer
| Article | Year |
|---|---|
Cell kinetic analysis of human breast carcinomas.
Topics: Autoradiography; Breast Neoplasms; Cell Division; DNA, Neoplasm; Female; Flow Cytometry; Humans; Int | 1984 |
Prognostic and predictive value of thymidine labelling index in breast cancer.
Topics: Breast Neoplasms; Disease Progression; Female; Humans; Predictive Value of Tests; Prognosis; Prospec | 1998 |
Alteration of human breast tumor cell membrane functions by chromosome-mediated gene transfer.
Topics: Alkaline Phosphatase; Biological Transport, Active; Breast Neoplasms; Carcinoma, Intraductal, Noninf | 1979 |
A predictive in vitro assay for the sensitivity of human solid tumours to hyperthermia (42 degrees C) and its value in patient management.
Topics: Aged; Animals; Breast Neoplasms; Child; Child, Preschool; DNA, Neoplasm; Evaluation Studies as Topic | 1976 |
[Ki-67 antigen, a cell cycle and tumor growth marker].
Topics: Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colonic Neoplasms; Flow Cytometry; G1 Phase; Human | 1991 |
Flow cytometry of breast cancer.
Topics: Aneuploidy; Breast Neoplasms; DNA, Neoplasm; Female; Flow Cytometry; Humans; Neoplasm Staging; Progn | 1991 |
Proliferation of cultivated cells from normal, preneoplastic and neoplastic human breast tissue--preliminary report.
Topics: Breast; Breast Neoplasms; Cell Division; Cell Line; Cells, Cultured; DNA Replication; Epithelial Cel | 1990 |
Intraductal noninvasive breast cancer: a comparison of three local treatments.
Topics: Breast Neoplasms; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; Combined Modality Ther | 1989 |
Steroid receptors and other prognostic factors in primary breast cancer.
Topics: Breast Neoplasms; Cell Division; Female; Flow Cytometry; Gene Amplification; Humans; Oncogenes; Ploi | 1988 |
[Relation between prolactin and breast cancer].
Topics: Anthracenes; Breast Neoplasms; DNA; Estrogens; Female; Humans; Pituitary Gland; Prolactin; Thymidine | 1974 |
8 trials available for thymidine and Breast Cancer
| Article | Year |
|---|---|
[Analysis of the prophylactic effect of nucleosides against reactivation of HBV in HBsAg-positive patients with non-hepatic tumors after chemotherapy].
Topics: Adult; Antineoplastic Agents; Antiviral Agents; Breast Neoplasms; Female; Follow-Up Studies; Guanine | 2010 |
Immunohistochemical determination of nuclear antigens by colour image analysis: application for labelling index, estrogen and progesterone receptor status in breast cancer.
Topics: Antigens, Neoplasm; Breast Neoplasms; Bromodeoxyuridine; Color; Humans; Image Processing, Computer-A | 1994 |
Changes in biological markers after primary chemotherapy for breast cancers.
Topics: Aneuploidy; Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Breast Neoplasms; Cell Cycle | 1995 |
Effects of primary chemotherapy on biological parameters of locally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Ci | 1996 |
Association between [18F]fluorodeoxyglucose uptake and postoperative histopathology, hormone receptor status, thymidine labelling index and p53 in primary breast cancer: a preliminary observation.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Female; Fluorodeoxyglucose F18; Humans; Middle Age | 1998 |
Thymidine labeling index analysis in early breast cancer patients randomized to receive perioperative chemotherapy.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chemotherapy, Adjuvant; Fem | 2001 |
Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from blood of women scheduled for breast biopsy.
Topics: Biomarkers, Tumor; Biopsy, Needle; Breast Neoplasms; DNA; Incidence; Mass Screening; Oxidative Stres | 2001 |
Tumor cytotoxicity. Quantitative changes in DNA synthesis as an indicator.
Topics: Animals; Antineoplastic Agents; Autoradiography; Breast Neoplasms; Carcinoma, Ehrlich Tumor; Clinica | 1966 |
328 other studies available for thymidine and Breast Cancer
| Article | Year |
|---|---|
Analytical and clinical characterization of an optimized dual monoclonal sandwich ELISA for the quantification of thymidine kinase 1 (TK1) protein in human blood samples.
Topics: Antibodies, Monoclonal; Biomarkers, Tumor; Breast Neoplasms; DNA; Enzyme-Linked Immunosorbent Assay; | 2022 |
Metronidazole affects breast cancer cell lines.
Topics: Breast Neoplasms; Cell Survival; DNA; Dose-Response Relationship, Drug; Estrogens; Female; Humans; M | 2013 |
Effects of environmental organochlorine pesticides on human breast cancer: putative involvement on invasive cell ability.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; DDT; DNA; Endocrine Disruptor | 2015 |
Palmitic acid and ergosta-7,22-dien-3-ol contribute to the apoptotic effect and cell cycle arrest of an extract from Marthasterias glacialis L. in neuroblastoma cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biological Products; Blotting, Western; Breast Neoplasms; | 2013 |
Nucleoside-catabolizing enzymes in mycoplasma-infected tumor cell cultures compromise the cytostatic activity of the anticancer drug gemcitabine.
Topics: Animals; Antimetabolites, Antineoplastic; Bacterial Proteins; Breast Neoplasms; Cell Line, Tumor; De | 2014 |
Expression of miR-34c induces G2/M cell cycle arrest in breast cancer cells.
Topics: Apc8 Subunit, Anaphase-Promoting Complex-Cyclosome; Breast Neoplasms; Cell Line, Tumor; Cell Prolife | 2014 |
Base-modified thymidines capable of terminating DNA synthesis are novel bioactive compounds with activity in cancer cells.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; DNA Replication; Female; Humans; MCF-7 Cells; Nuc | 2015 |
[18F]FDG and [18F]FLT uptake in human breast cancer cells in relation to the effects of chemotherapy: an in vitro study.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Doxorubicin; Fluorodeoxygluco | 2008 |
Novel opportunities for thymidylate metabolism as a therapeutic target.
Topics: Adenocarcinoma; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Computational Biology; DN | 2008 |
High-throughput hacking of the methylation patterns in breast cancer by in vitro transcription and thymidine-specific cleavage mass array on MALDI-TOF silico-chip.
Topics: Base Sequence; Biomarkers, Tumor; Breast Neoplasms; DNA Methylation; Female; Genes, Tumor Suppressor | 2008 |
Evaluation of urinary nucleosides in breast cancer patients before and after tumor removal.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenosine; Adult; Breast Neoplasms; Chromatography, Liquid; Deoxyguanos | 2009 |
3'-Deoxy-3'-[(18)F]fluorothymidine (FLT) uptake in breast cancer cells as a measure of proliferation after doxorubicin and docetaxel treatment.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Docetaxel; Doxorubicin; Female; Fluorine Rad | 2009 |
MCF-7 human mammary adenocarcinoma cells exhibit augmented responses to human insulin on a collagen IV surface.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cell Line, Tumor; Collagen Type IV; Dose-Response Relatio | 2009 |
Synthesis and cytotoxic activity of novel amidine analogues of bis(2-chloroethyl)amine.
Topics: Amidines; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; DNA; Drug Screen | 2009 |
A small-molecule inhibitor, 5'-O-tritylthymidine, targets FAK and Mdm-2 interaction, and blocks breast and colon tumorigenesis in vivo.
Topics: Animals; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Coloni | 2013 |
Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Ataxia Telangiectasia Mutated P | 2012 |
Basal expression of the multidrug resistance gene 1 (MDR-1) is associated with the TT genotype at the polymorphic site C3435T in mammary and ovarian carcinoma cell lines.
Topics: Adenocarcinoma; beta 2-Microglobulin; Breast Neoplasms; DNA Primers; Drug Resistance, Multiple; Drug | 2002 |
Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng.
Topics: Breast Neoplasms; Central Nervous System Agents; Drugs, Chinese Herbal; Estradiol; Estrogen Antagoni | 2002 |
Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: reciprocal involvement of PKC-alpha and PPAR expression.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Division; Cyclin D1; Cyclin-Dependent Kinase | 2002 |
Stereoselective and improved syntheses and anticancer testing of 3'-O-silatranylthymidines.
Topics: Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; C | 2002 |
Effects of tenuiorin and methyl orsellinate from the lichen Peltigera leucophlebia on 5-/15-lipoxygenases and proliferation of malignant cell lines in vitro.
Topics: Breast Neoplasms; Cell Division; Cell Extracts; Humans; Inhibitory Concentration 50; Lichens; Lipoxy | 2002 |
Relationship between the thymidine labeling and Ki-67 proliferative indices in 126 breast cancer patients.
Topics: Autoradiography; Breast Neoplasms; Cell Division; Female; Humans; Immunohistochemistry; Ki-67 Antige | 2002 |
Insulin-like growth factor-binding protein-5 inhibits the growth of human breast cancer cells in vitro and in vivo.
Topics: Adenoviridae; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; bcl-2-Associated X Protein; Blott | 2003 |
1alpha,25-Dihydroxyvitamin D3-3beta-(2)-bromoacetate, an affinity labeling derivative of 1alpha,25-dihydroxyvitamin D3 displays strong antiproliferative and cytotoxic behavior in prostate cancer cells.
Topics: Affinity Labels; Apoptosis; Breast Neoplasms; Calcitriol; Cell Division; Cell Line; Cell Survival; D | 2003 |
Cytostatic and immunomobilizing activities of polymer-bound drugs: experimental and first clinical data.
Topics: Adult; Animals; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antineoplastic Agents; Blood Ce | 2003 |
Autoradiographic analysis of cell proliferation in spontaneous breast cancer of C3H mouse. I. Growth and survival of cells labeled with tritiated thymidine.
Topics: Animals; Breast Neoplasms; Carcinoma; Cell Proliferation; Humans; Mice; Mice, Inbred C3H; Nucleoside | 1960 |
The incorporation of tritiated thymidine into the DNA of human breast tumors in vitro.
Topics: Autoradiography; Biochemical Phenomena; Breast Neoplasms; DNA; Estradiol; Formates; Humans; In Vitro | 1962 |
Distribution of tritiated thymidine about a capillary sinusoid in a transplanted mouse tumour.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Capillaries; Humans; Mammary Neoplasms, Animal; Mammary N | 1962 |
AVAILABILITY OF TRITIATED THYMIDINE AFTER INTRAVENOUS ADMINISTRATION.
Topics: Administration, Intravenous; Animals; Autoradiography; Breast Neoplasms; Colchicine; DNA; Humans; In | 1964 |
AUTORADIOGRAPHIC MEASUREMENT OF TUMOR GROWTH.
Topics: Animals; Autoradiography; Breast Neoplasms; Catheterization; DNA; DNA, Neoplasm; Humans; Mammary Neo | 1964 |
Chronic infusion of tritiated thymidine into mice with tumors.
Topics: Animals; Breast Neoplasms; Humans; Mice; Neoplasms; Neoplasms, Experimental; Nucleosides; Nucleotide | 1962 |
Role of extracellular matrix in insulin-like growth factor (IGF) binding protein-2 regulation of IGF-II action in normal human osteoblasts.
Topics: Animals; Apoptosis; Bone Neoplasms; Breast Neoplasms; Cattle; Cell Division; Cells, Cultured; Collag | 2003 |
The DNMT3B C-->T promoter polymorphism and risk of breast cancer in a British population: a case-control study.
Topics: Adult; Age of Onset; Aged; Breast Neoplasms; Case-Control Studies; Cytosine; DNA (Cytosine-5-)-Methy | 2004 |
Thymidine labeling index: prognostic role in breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Combin | 2004 |
Adenosine stimulation of proliferation of breast carcinoma cell lines: evaluation of the [3H]thymidine assay system and modulatory effects of the cellular microenvironment in vitro.
Topics: Adenosine; Breast Neoplasms; Cell Count; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Culture M | 2004 |
Can transforming growth factor-beta1 and retinoids modify the activity of estradiol and antiestrogens in MCF-7 breast cancer cells?.
Topics: Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogen Receptor Modu | 2004 |
Inhibition of cell proliferation in human breast tumor cells by antisense oligonucleotides against facilitative glucose transporter 5.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Proliferation; Female; Fructose | 2004 |
Enhanced tumor cell radiosensitivity and abrogation of G2 and S phase arrest by the Hsp90 inhibitor 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin.
Topics: Administration, Oral; Animals; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Com | 2004 |
Breast carcinoma malignancy grading by Bloom-Richardson system vs proliferation index: reproducibility of grade and advantages of proliferation index.
Topics: Breast Neoplasms; Bromodeoxyuridine; Cell Nucleus; Cell Proliferation; DNA, Neoplasm; Female; Humans | 2005 |
Differential effects of estrogen on DNA synthesis in human periodontal ligament and breast cancer cells.
Topics: Adolescent; Breast Neoplasms; Cell Line, Tumor; Cells, Cultured; Collagen; DNA; Estradiol; Estrogen | 2005 |
Estrogen receptor alpha binds to peroxisome proliferator-activated receptor response element and negatively interferes with peroxisome proliferator-activated receptor gamma signaling in breast cancer cells.
Topics: Breast Neoplasms; Cell Proliferation; Chromatin Immunoprecipitation; Electrophoretic Mobility Shift | 2005 |
Microgravity alters basal and insulin-mediated metabolic activity of normal and neoplastic cells.
Topics: Amino Acids; Animals; Bioreactors; Breast Neoplasms; Cell Line; Cell Proliferation; Endothelium, Vas | 2004 |
Human breast cell lines exhibit functional alpha2-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Binding, Competitive; Breast; Breast Neoplasms; Cell Line; Cell Line, Tum | 2006 |
Polymorphisms in thymidylate synthase gene and susceptibility to breast cancer in a Chinese population: a case-control analysis.
Topics: 3' Untranslated Regions; 5' Untranslated Regions; Adult; Aged; Breast Neoplasms; Case-Control Studie | 2006 |
Novel amidine analogue of melphalan as a specific multifunctional inhibitor of growth and metabolism of human breast cancer cells.
Topics: Amidines; Animals; Antineoplastic Agents, Alkylating; Blotting, Western; Breast Neoplasms; Cell Line | 2006 |
Impact of constitutive IGF1/IGF2 stimulation on the transcriptional program of human breast cancer cells.
Topics: Animals; Blotting, Western; Breast Neoplasms; Cell Proliferation; Cell Survival; Drug Resistance, Ne | 2007 |
Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Breas | 2007 |
Amidine analogues of melphalan: synthesis, cytotoxic activity, and DNA binding properties.
Topics: Amidines; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Surviv | 2007 |
Effect of spider venom on cell apoptosis and necrosis rates in MCF-7 cells.
Topics: Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Survival; Electric Stimulation; Fema | 2007 |
Piper cubeba demonstrates anti-estrogenic and anti-inflammatory properties.
Topics: Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Breast Neoplasms; Cell Line, Tumor; Cyclooxyg | 2008 |
[Interaction between explanted mammary tumors and gonads in the confrontation culture].
Topics: Aged; Animals; Breast Neoplasms; Culture Techniques; Female; Gonads; Hormones; Humans; Male; Middle | 1967 |
Effect of retinoic acid and 4-hydroxytamoxifen on human breast cancer cell lines.
Topics: Breast Neoplasms; Carrier Proteins; Cell Division; Cell Line; Cytosol; Estrogen Antagonists; Female; | 1984 |
5-Fluorouracil incorporation in DNA of human breast carcinoma cells.
Topics: Breast Neoplasms; Cell Line; DNA Replication; DNA, Neoplasm; Female; Floxuridine; Fluorouracil; Huma | 1982 |
Interactions between human fibroblasts and HeLa cells in vitro.
Topics: Autoradiography; Breast Neoplasms; Cell Communication; Cell Line; DNA Replication; Female; Fibroblas | 1984 |
[In vitro cultivation of vital tissue slices: a new variation of organ culture technics].
Topics: Breast Neoplasms; Culture Techniques; DNA, Neoplasm; Humans; Microbial Collagenase; Organ Culture Te | 1983 |
A method for dissociation of viable human breast cancer cells that produces flow cytometric kinetic information similar to that obtained by thymidine labeling.
Topics: Breast Neoplasms; Cell Separation; Cell Survival; DNA Replication; Female; Flow Cytometry; Humans; K | 1984 |
Hormonal control of plasminogen activator secretion in ZR-75-1 human breast cancer cells in culture.
Topics: Breast Neoplasms; Cells, Cultured; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Femal | 1984 |
Combined cytotoxic and endocrine therapy for human breast carcinoma (Br-10) serially transplanted into nude mice.
Topics: Adult; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Mi | 1984 |
[In vitro inhibition of DNA replication by local anesthetics. Effects on human MCF7 neoplastic cells].
Topics: Breast Neoplasms; Bupivacaine; Cell Line; DNA Replication; Dose-Response Relationship, Drug; Female; | 1983 |
[Estradiol and 3 H-thymidine incorporation in cultured human cancer cells (breast-endometrium)].
Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Cell Line; DNA, Neoplasm; Estradiol; Female; Humans | 1983 |
The errors of thymidine labelling in breast cancer.
Topics: Breast Neoplasms; Cell Division; Female; Humans; Mitosis; Mitotic Index; Prognosis; Statistics as To | 1983 |
Influence of mitoxantrone on nucleic acid synthesis on the T-47D breast tumor cell line.
Topics: Anthraquinones; Breast Neoplasms; Cell Line; Cells, Cultured; DNA, Neoplasm; Female; Humans; Mitoxan | 1983 |
Correlations between clonogenicity and prognostic factors in human breast cancer.
Topics: Breast Neoplasms; Clone Cells; Female; Humans; Prognosis; Receptors, Estrogen; Thymidine | 1984 |
Influence of cell proliferation and cell cycle phase on expression of estrogen receptor in MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Female; Humans; Isoleucine; Receptors, Estro | 1984 |
The long-term prognostic significance of the thymidine labelling index in breast cancer.
Topics: Autoradiography; Axilla; Breast Neoplasms; Female; Follow-Up Studies; Humans; Lymphatic Metastasis; | 1984 |
Development of selectively acting platinum complexes.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Chromatin; DNA; Female; Humans; In Vitro Technique | 1984 |
N,N'-Dialkyl-1,2-bis(hydroxyphenyl)ethylenediamines and N,N-dialkyl-4,5-bis(4-hydroxyphenyl)imidazolidines: syntheses and evaluation of their mammary tumor inhibiting activity.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; C | 1982 |
Serum regulation of the estrogen responsiveness of the human breast cancer cell line MCF-7.
Topics: Blood; Breast Neoplasms; Cell Count; Cell Division; Cell Line; Estradiol; Female; Humans; Karyotypin | 1983 |
Prediction of early course of breast carcinoma by thymidine labeling.
Topics: Breast Neoplasms; DNA, Neoplasm; Female; Humans; In Vitro Techniques; Menopause; Middle Aged; Neopla | 1983 |
Epidermal growth factor stimulation of human breast cancer cells in culture.
Topics: Animals; Breast Neoplasms; Cell Count; Cell Line; Dexamethasone; DNA; Epidermal Growth Factor; Femal | 1980 |
Influence of estradiol on the total uptake and incorporation of thymidine in human breast cancer (MCF-7) in long-term cell culture. Comparison of autoradiographic and biochemical methods.
Topics: Autoradiography; Breast Neoplasms; Cell Division; Cells, Cultured; DNA, Neoplasm; Estradiol; Humans; | 1982 |
Hormonal regulation of net DNA synthesis in MCF-7 human breast cancer cells in tissue culture.
Topics: Breast Neoplasms; Cell Line; Culture Media; DNA; Estradiol; Estrogen Antagonists; Estrogens; Humans; | 1982 |
[Pretherapeutical testing of antineoplastic drugs in vitro (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Culture Techniques; DNA; Drug Resistance; Humans; Neoplasms | 1982 |
Estrogen receptor heterogeneity and the relationship between estrogen receptor and the tritiated thymidine labeling index in human breast cancer.
Topics: Breast Neoplasms; Female; Humans; Menopause; Neoplasm Staging; Prognosis; Receptors, Estrogen; Thymi | 1982 |
Cell proliferation in fibrocystic disease and postmenopause breast ducts measured by thymidine labeling.
Topics: Adolescent; Adult; Age Factors; Aged; Breast; Breast Diseases; Breast Neoplasms; Cell Count; Cell Di | 1982 |
Short-term culture of human breast cancer: in vitro effects of hormones related to patient response.
Topics: Breast Neoplasms; Cells, Cultured; Estradiol; Female; Hormones; Humans; In Vitro Techniques; Menopau | 1982 |
Vitamin B6 kills hepatoma cells in culture.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Count; Cell Division; | 1982 |
Methods for determining chemosensitivity of MCF-7 cells in double-layer agar culture: labeling index depression and colony count inhibition.
Topics: Adenocarcinoma; Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Line; Clone Cells; Hu | 1982 |
Mitogenic activity and plasminogen activator in harvest fluid concentrates from mammary cells in culture.
Topics: Animals; Breast; Breast Neoplasms; Cell Line; Extracellular Space; Female; Growth Substances; Humans | 1980 |
Failure of 5-fluorouracil and methotrexate to destroy the reproductive integrity of a human breast cancer cell line (MCF-7) growing in vitro.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Survival; Clone Cells; Deoxyuridine; DNA, Neoplasm; | 1981 |
Kinetic parameters and the course of the disease in breast cancer.
Topics: Breast Neoplasms; Cell Division; Female; Follow-Up Studies; Humans; Kinetics; Neoplasm Metastasis; P | 1981 |
Effects of 17 beta-estradiol on progesterone receptors and the uptake of thymidine in human breast cancer cell line CAMA-1.
Topics: Biological Transport; Breast Neoplasms; Cell Line; DNA, Neoplasm; Estradiol; Female; Humans; Neoplas | 1981 |
Measurements of DNA synthesis and estrogen receptor in needle aspirates as powerful methods in the management of mammary carcinoma.
Topics: Biopsy, Needle; Breast Neoplasms; DNA, Neoplasm; Estradiol; Estrogen Antagonists; Female; Humans; Re | 1980 |
Interaction of prolactin, estrogen and progesterone in a human mammary carcinoma cell line, CAMA-1 - I Cell growth and thymidine uptake.
Topics: Breast Neoplasms; Cell Division; Cell Line; Culture Media; Estradiol; Female; Humans; Neoplasms, Hor | 1981 |
Possible test for selection of adjuvant systemic therapy in early cancer of the breast.
Topics: Breast Neoplasms; Female; Humans; Lymphatic Metastasis; Mitotic Index; Neoplasm Recurrence, Local; R | 1980 |
The effects of 17 beta estradiol and tamoxifen on the ZR-75-1 human breast cancer cell line in defined medium.
Topics: Acetates; Breast Neoplasms; Cell Division; Cell Line; Culture Media; Estradiol; Female; Humans; Leuc | 1980 |
Purification and properties of estrogen-responsive cytoplasmic thymidine kinase from human breast cancer.
Topics: Breast Neoplasms; Cell Line; Estradiol; Female; Humans; Kinetics; Mitochondria; Neoplasms, Hormone-D | 1981 |
[3H-thymidine incorporation under endocrine influence and hormone receptor content of human mammary carcinoma (author's transl)].
Topics: Breast Neoplasms; Estradiol; Female; Humans; Medroxyprogesterone; Receptors, Estrogen; Receptors, Pr | 1980 |
Insulin-like growth factor binding protein 3 (IGF-BP3) inhibits estrogen-stimulated breast cancer cell proliferation.
Topics: Breast Neoplasms; Carrier Proteins; Cell Division; Cell Line; DNA, Neoplasm; Estradiol; Humans; Insu | 1994 |
Role of tumor-derived fibroblasts in the growth of primary cultures of human breast-cancer cells: effects of epidermal growth factor and the somatostatin analogue octreotide.
Topics: Adult; Aged; Breast Neoplasms; Bromodeoxyuridine; Cell Communication; Cell Division; Epidermal Growt | 1995 |
Detection of P53 expression and S-phase cell fraction in paraffin-embedded tissue by a double-labeling technique.
Topics: Antibodies, Monoclonal; Autoradiography; Breast Neoplasms; Cell Cycle; Cell Division; Female; Humans | 1995 |
Relaxin activates the L-arginine-nitric oxide pathway in human breast cancer cells.
Topics: Arginine; Breast Neoplasms; Cyclic GMP; Female; Humans; Nitric Oxide; Nitric Oxide Synthase; Relaxin | 1995 |
Antiproliferative activity of gossypol and gossypolone on human breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Drug Resistance, Multiple; Drug Screening As | 1995 |
Effects of indomethacin with or without linoleic acid on human breast cancer cells in vitro.
Topics: Breast Neoplasms; Cell Division; DNA, Neoplasm; Female; Humans; Indomethacin; Leukotriene B4; Linole | 1995 |
Heterogeneity of intratumour proliferative activity in primary breast cancer: biological and clinical aspects.
Topics: Breast Neoplasms; Cell Division; Disease-Free Survival; Female; Follow-Up Studies; Humans; Isotope L | 1995 |
Increased sensitivity to the prodrug 5'-deoxy-5-fluorouridine and modulation of 5-fluoro-2'-deoxyuridine sensitivity in MCF-7 cells transfected with thymidine phosphorylase.
Topics: Antineoplastic Agents; Biological Availability; Breast; Breast Neoplasms; Cell Communication; Cell D | 1995 |
Estrogen and antiestrogen modulation of MCF7 human breast cancer cell proliferation is associated with specific alterations in accumulation of insulin-like growth factor-binding proteins in conditioned media.
Topics: Antineoplastic Agents; Breast Neoplasms; Carrier Proteins; Cell Division; Cell Line; Culture Media, | 1993 |
Cyclic adenosine monophosphate (cAMP) analogs 8-Cl- and 8-NH2-cAMP induce cell death independently of cAMP kinase-mediated inhibition of the G1/S transition in mammary carcinoma cells (MCF-7).
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Breast Neoplasms; Cell Death; Cell Division; Colforsin; Cycl | 1995 |
Raf-1 protein expression in human breast cancer cells.
Topics: Breast Neoplasms; Culture Media; DNA, Neoplasm; Enzyme Activation; Epidermal Growth Factor; ErbB Rec | 1995 |
Relationship of variations in tumor cell kinetics induced by primary chemotherapy to tumor regression and prognosis in locally advanced breast cancer.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Chemot | 1994 |
Assessment of proliferating cell nuclear antigen (PCNA) in breast cancer using anti-PCNA PC10 and 19A2: correlation with 5-bromo-2'-deoxyuridine or tritiated thymidine labeling and flow cytometric analysis.
Topics: Antibodies, Monoclonal; Breast Neoplasms; Bromodeoxyuridine; Cell Division; Flow Cytometry; Formalde | 1994 |
Alterations in transforming growth factor-alpha and -beta production and cell responsiveness during the progression of MCF-7 human breast cancer cells to estrogen-autonomous growth.
Topics: Breast Neoplasms; Cell Division; Culture Media; Dose-Response Relationship, Drug; Estradiol; Humans; | 1994 |
Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications.
Topics: Breast Neoplasms; Cell Division; Cell Line; Eflornithine; Estradiol; Female; Flow Cytometry; G1 Phas | 1994 |
[The labelling index as a prognostic marker in breast carcinoma].
Topics: Adult; Aged; Aged, 80 and over; Autoradiography; Biomarkers, Tumor; Breast Neoplasms; Carcinoma, Duc | 1994 |
Downregulation of lymphocyte mitogenesis by breast cancer-associated p43.
Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Lymphocyte Activation; Middle Aged; Neoplasm Proteins | 1994 |
Scanning electron microscopy of multidrug resistant cells in haematological and mammary malignancies.
Topics: Acute Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Breas | 1993 |
Inhibition of thymidine kinase in cultured mammary tumor cells by the chemopreventive organoselenium compound, 1,4-phenylenebis(methylene)selenocyanate.
Topics: Adenosine Triphosphate; Animals; Binding, Competitive; Breast Neoplasms; Cell Division; Growth Inhib | 1994 |
Gossypol inhibits basal and estrogen-stimulated DNA synthesis in human breast carcinoma cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Re | 1993 |
Clinical relevance of cell kinetics in breast cancer.
Topics: Age Factors; Breast Neoplasms; Cell Cycle; Female; Follow-Up Studies; Humans; Kinetics; Lymphatic Me | 1993 |
Selective antiproliferative effects of thymidine.
Topics: Animals; Breast Neoplasms; Cell Cycle; Cell Division; Cell Survival; Female; Humans; Kinetics; Lymph | 1993 |
Toxicity, single-strand breaks, and 5-hydroxymethyl-2'-deoxyuridine formation in human breast epithelial cells treated with hydrogen peroxide.
Topics: Antioxidants; Breast Neoplasms; Catalase; DNA Damage; Epithelium; Free Radicals; Glutathione Reducta | 1993 |
Growth arrest of the breast cancer cell line, T47D, by TNF alpha; cell cycle specificity and signal transduction.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltra | 1993 |
Reversible inhibition of proliferation of epithelial cell lines by Agaricus bisporus (edible mushroom) lectin.
Topics: Adenocarcinoma; Adult; Agaricus; Aged; Animals; Arachis; Binding Sites; Breast Neoplasms; Carbohydra | 1993 |
Prognostic significance of proliferative activity and ploidy in node-negative breast cancers.
Topics: Breast Neoplasms; Cell Division; Female; Flow Cytometry; Follow-Up Studies; Humans; Kinetics; Lympha | 1993 |
Aromatase activity and the effect of estradiol and testosterone on DNA synthesis in endometrial carcinoma cell lines.
Topics: Aromatase; Breast Neoplasms; DNA Replication; Dose-Response Relationship, Drug; Endometrial Neoplasm | 1993 |
Bromodeoxyuridine labeling for S-phase measurement in breast carcinoma.
Topics: Breast Neoplasms; Bromodeoxyuridine; Carcinoma; Cryopreservation; Female; Humans; In Vitro Technique | 1993 |
Antiproliferative effect of DNA polymerase alpha antisense oligodeoxynucleotides on breast cancer cells.
Topics: Adenocarcinoma; Base Sequence; Breast Neoplasms; Cell Division; DNA Polymerase II; DNA Replication; | 1993 |
Cell kinetics as a predictive factor in node-positive breast cancer treated with adjuvant hormone therapy.
Topics: Aged; Breast Neoplasms; Cell Division; Chemotherapy, Adjuvant; Female; Humans; Lymphatic Metastasis; | 1993 |
Levels of 5-hydroxymethyl-2'-deoxyuridine in DNA from blood as a marker of breast cancer.
Topics: Biomarkers, Tumor; Breast Neoplasms; DNA; DNA Damage; Female; Humans; Middle Aged; Odds Ratio; Pilot | 1996 |
Modulation of the length of the cell cycle time of MCF-7 human breast cancer cells by melatonin.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; DNA, Neoplasm; Female; Humans; Melatonin; Mitosis; Thym | 1996 |
Melatonin inhibits DNA synthesis in MCF-7 human breast cancer cells in vitro.
Topics: Breast Neoplasms; Cell Division; DNA; Female; Humans; Melatonin; Thymidine; Tumor Cells, Cultured | 1996 |
Hydrogen peroxide induces the catabolism of polyamines in human breast cancer cells.
Topics: Acetyltransferases; Antioxidants; Breast Neoplasms; DNA, Neoplasm; Female; Humans; Hydrogen Peroxide | 1996 |
Stearate inhibition of breast cancer cell proliferation. A mechanism involving epidermal growth factor receptor and G-proteins.
Topics: Adenosine Diphosphate Ribose; Breast Neoplasms; Cell Division; Dose-Response Relationship, Drug; Epi | 1996 |
Cell proliferation in 3,800 node-negative breast cancers: consistency over time of biological and clinical information provided by 3H-thymidine labelling index.
Topics: Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Cell Division; Confidence Intervals; DNA, Neoplasm | 1997 |
Cell proliferation as a predictor of response to chemotherapy in metastatic breast cancer: a prospective study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Division; Cyclop | 1997 |
Suppression of human cancer cell proliferation by lipoxygenase inhibitors and gamma-radiation in vitro.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Cell Survival; Cyclooxygenase Inhibitors; DN | 1996 |
L-histidine/medroxyprogesterone acetate interaction modulates human breast cancer cell growth and progestin receptor expression in vitro.
Topics: Breast Neoplasms; Cell Count; Cell Division; Drug Synergism; Histidine; Humans; Kinetics; Medroxypro | 1997 |
New nucleoside-5'-alkylphosphonophosphates and related compounds containing 2'-deoxycytidine, thymidine and adenosine as nucleoside component. Syntheses and their effects on tumor cell growth in vitro.
Topics: Adenosine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Chromatography, Thin Lay | 1997 |
Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ErbB-2 in human carcinoma cell lines.
Topics: 3T3 Cells; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Breast Neoplasms; | 1997 |
Effect of bile acids and estradiol on thymidine incorporation into DNA in MCF-7 and MCF-10A breast cell lines.
Topics: Bile Acids and Salts; Breast Neoplasms; DNA; Estradiol; Fibrocystic Breast Disease; Humans; Thymidin | 1997 |
Serum autoantibodies recognizing 5-hydroxymethyl-2'-deoxyuridine, an oxidized DNA base, as biomarkers of cancer risk in women.
Topics: Adult; Age Factors; Aged; Autoantibodies; Biomarkers, Tumor; Breast Neoplasms; Colorectal Neoplasms; | 1998 |
Preparation, characterization and in vitro efficacy of albumin conjugates of doxorubicin.
Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Bromodeoxyuridine; Chromatography, High Pressure Liqu | 1998 |
Influence of leukotrienes on in vitro growth of human mammary carcinoma cell line MCF-7.
Topics: Acetophenones; Arachidonic Acid; Breast Neoplasms; Calcimycin; Carcinoma; Cell Division; Female; Hum | 1998 |
Thymidine phosphorylase moderates thymidine-dependent rescue after exposure to the thymidylate synthase inhibitor ZD1694 (Tomudex) in vitro.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Culture Media, Conditioned; Dose-Response Relatio | 1998 |
Influence of 5-lipoxygenase on in vitro growth of human mammary carcinoma cell line MCF-7.
Topics: Arachidonate 5-Lipoxygenase; Breast Neoplasms; Calcimycin; Cell Division; Chromatography, High Press | 1998 |
Antiproliferative action of tumor necrosis factor-alpha on MCF-7 breastcancer cells is associated with increased insulin-like growth factor binding protein-3 accumulation.
Topics: Antineoplastic Agents; Blotting, Northern; Breast Neoplasms; Cell Division; Dose-Response Relationsh | 1998 |
Interleukin 6 acts as a paracrine growth factor in human mammary carcinoma cell lines.
Topics: Apoptosis; Breast Neoplasms; Female; Growth Substances; Humans; Interleukin-6; Receptors, Estrogen; | 1996 |
Acetaminophen alters estrogenic responses in vitro: stimulation of DNA synthesis in estrogen-responsive human breast cancer cells.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Breast Neoplasms; DNA, Neoplasm; Estrogens; Flow Cytometry; | 1998 |
Acetaminophen-induced proliferation of breast cancer cells involves estrogen receptors.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Binding, Competitive; Breast Neoplasms; Cell Count | 1999 |
Overexpression of c-Myc inhibits p21WAF1/CIP1 expression and induces S-phase entry in 12-O-tetradecanoylphorbol-13-acetate (TPA)-sensitive human cancer cells.
Topics: Adenoviridae; Apoptosis; Blotting, Western; Breast Neoplasms; Bromodeoxyuridine; Cell Division; Cycl | 1999 |
Magnesium depletion causes growth inhibition, reduced expression of cyclin D1, and increased expression of P27Kip1 in normal but not in transformed mammary epithelial cells.
Topics: Animals; Breast Neoplasms; Cell Cycle Proteins; Cell Division; Cell Line, Transformed; Cyclin D1; Cy | 1999 |
Lactoferrin inhibits G1 cyclin-dependent kinases during growth arrest of human breast carcinoma cells.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cell Cycle Proteins; Cell Division; Colonic Neopla | 1999 |
Effects of antiprogestins on the rate of proliferation of breast cancer cells.
Topics: Blood; Breast Neoplasms; Cell Division; Charcoal; Estrogens; Hormone Antagonists; Humans; Progestins | 1999 |
In vitro DNA synthesis in freshly separated human breast cancer cells assessed by tritiated thymidine incorporation assay: relationship to the long-term outcome of patients.
Topics: Analysis of Variance; Breast Neoplasms; DNA, Neoplasm; Female; Follow-Up Studies; Humans; Middle Age | 1999 |
Synthesis and reactivity of a potential carcinogenic metabolite of tamoxifen: 3,4-dihydroxytamoxifen-o-quinone.
Topics: Animals; Breast Neoplasms; Carcinogens; Chromatography, High Pressure Liquid; Deoxyguanosine; Glutat | 2000 |
Comparison between different cell kinetic variables in human breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antigens, Nuclear; Breast Neoplasms; Cell Cycle; DNA-Binding Protein | 2000 |
Recruitment for a pilot case control study of oxidative DNA damage and breast cancer risk.
Topics: Antineoplastic Agents; Breast Neoplasms; Case-Control Studies; DNA Damage; Female; Humans; Logistic | 2000 |
Role of MAP kinase in the enhanced cell proliferation of long term estrogen deprived human breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Estradiol; | 2000 |
Prognostic significance of biologic markers in node-negative breast cancer patients: a prospective study.
Topics: Adult; Aged; Biomarkers; Breast Neoplasms; Cell Division; Female; Humans; Lymphatic Metastasis; Micr | 2000 |
Disruption of mitochondrial respiration by melatonin in MCF-7 cells.
Topics: Adenocarcinoma; Adenosine Triphosphate; Antioxidants; Breast Neoplasms; Cell Respiration; Electron T | 2001 |
Growth-inhibitory effects of CD40 ligand (CD154) and its endogenous expression in human breast cancer.
Topics: Animals; Annexin A5; Apoptosis; Blotting, Western; Breast Neoplasms; Carcinoma; CD40 Antigens; CD40 | 2001 |
beta-estradiol stimulation of DNA synthesis requires different PKC isoforms in HepG2 and MCF7 cells.
Topics: Androstadienes; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Division; Cell Membrane; DNA Repli | 2001 |
Autocrine TGFbeta signaling mediates vitamin D3 analog-induced growth inhibition in breast cells.
Topics: Activin Receptors, Type I; Antibodies, Blocking; Antineoplastic Agents; Autocrine Communication; Bre | 2001 |
Predictability of monthly and yearly rhythms of breast cancer features.
Topics: Breast Neoplasms; Female; Humans; Lymph Node Excision; Menopause; Menstrual Cycle; Periodicity; Rece | 2001 |
The Brn-3b POU family transcription factor regulates the cellular growth, proliferation, and anchorage dependence of MCF7 human breast cancer cells.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Division; Cell Line, Transformed; DNA-Binding Proteins; Estra | 2001 |
Signaling and antiproliferative effects mediated by GnRH receptors after expression in breast cancer cells using recombinant adenovirus.
Topics: Adenoviridae; Binding, Competitive; Breast Neoplasms; Cell Division; Female; Gene Transfer Technique | 2001 |
A multistep model for paclitaxel-induced apoptosis in human breast cancer cell lines.
Topics: Amino Acid Chloromethyl Ketones; Antineoplastic Agents, Phytogenic; Apoptosis; Breast Neoplasms; Cel | 2001 |
VIP receptor antagonists and chemotherapeutic drugs inhibit the growth of breast cancer cells.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclic AMP; Di | 2001 |
Biomarker prediction of clinical outcome in operable breast cancer patients treated with tamoxifen.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Hormonal; Biomarkers, Tumor; Breast Neoplasms; Chemo | 2001 |
Biological considerations in locally advanced breast cancer treated with anthracycline-based neoadjuvant chemotherapy: thymidine labelling index is an independent indicator of clinical outcome.
Topics: Adult; Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Axilla; Breast Neoplasms; DNA, Neop | 2001 |
13-cis retinoic acid and all-trans retinoic acid in the regulation of the proliferation and survival of human breast cancer cell line MCF-7.
Topics: Antineoplastic Agents; Antineoplastic Agents, Hormonal; Breast Neoplasms; Cell Division; Cell Surviv | 2001 |
Synergistic proliferative action of insulin-like growth factor I and 17 beta-estradiol in MCF-7S breast tumor cells.
Topics: Breast Neoplasms; CDC2-CDC28 Kinases; Cell Cycle; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase 2; Cy | 2002 |
Intracrine PTHrP protects against serum starvation-induced apoptosis and regulates the cell cycle in MCF-7 breast cancer cells.
Topics: Apoptosis; Blotting, Northern; Breast Neoplasms; Cell Count; Cell Cycle; Cell Nucleus; Culture Media | 2002 |
Cytotoxicity activity of L-proline analogues of anthraquinone-2-carboxylic acid in breast cancer MCF-7 cells.
Topics: Anthraquinones; Antineoplastic Agents; Breast Neoplasms; Carboxylic Acids; Female; Humans; Prodrugs; | 2001 |
Synthesis and antitumor activity of several new analogues of penclomedine and its metabolites.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Humans; Mice; Mice, Nude; Picolines; Structure-Act | 2002 |
Ethanol modulates the growth of human breast cancer cells in vitro.
Topics: Blotting, Western; Breast Neoplasms; Cell Division; Enzyme Activation; Ethanol; Humans; In Vitro Tec | 2002 |
Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line.
Topics: Blotting, Western; Breast Neoplasms; Carcinoma, Ductal, Breast; Carrier Proteins; Cell Division; DNA | 2002 |
Comparative assessment expression of the inhibitor of growth 1 gene (ING1) in normal and neoplastic tissues.
Topics: Adenoma; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blotting, Western; Breast Neoplasms; | 2002 |
Short-term rhythmic proliferation of human breast cancer cell lines: surface effects and fractal growth patterns.
Topics: Breast Neoplasms; Cell Division; Circadian Rhythm; Female; Fractals; Humans; Models, Biological; Rec | 2002 |
Leptin mediates a proliferative response in human MCF7 breast cancer cells.
Topics: Acute-Phase Proteins; Adipocytes; Breast Neoplasms; Cell Division; DNA-Binding Proteins; DNA, Neopla | 2002 |
IGF-binding protein-3-induced growth inhibition and apoptosis do not require cell surface binding and nuclear translocation in human breast cancer cells.
Topics: Adenoviridae; Apoptosis; Blotting, Western; Breast Neoplasms; Caspases; Cell Division; Cell Nucleus; | 2002 |
Combined application of cytodiagnostic technics to the cerebrospinal fluid.
Topics: Adenocarcinoma; Adolescent; Aged; Autoradiography; Brain Neoplasms; Breast Neoplasms; Central Nervou | 1977 |
Progesterone and glucocorticoid interactions with receptor in breast cancer cells in long-term tissue culture.
Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Cell Line; Dexamethasone; Female; Humans; Hyd | 1977 |
Tritiated thymidine labeling index and response in human breast cancer.
Topics: Antineoplastic Agents; Breast Neoplasms; Drug Therapy, Combination; Female; Humans; Middle Aged; Pro | 1979 |
"Rescue" techniques in cancer chemotherapy: use of leucovorin and other rescue agents after methotrexate treatment.
Topics: Animals; Asparaginase; Breast Neoplasms; Carboxypeptidases; Child; Drug Administration Schedule; Dru | 1977 |
Labeling index in clinical specimens estimated by the antinucleoside antibody technique.
Topics: Adenocarcinoma; Antibodies; Breast Neoplasms; DNA, Neoplasm; Female; Frozen Sections; Head and Neck | 1978 |
Direct inhibition of growth and antagonism of insulin action by glucocorticoids in human breast cancer cells in culture.
Topics: Acetates; Breast Neoplasms; Cell Division; Cells, Cultured; Dexamethasone; Female; Glucocorticoids; | 1979 |
Regression of human tumors established in nude mice after continuous infusion of thymidine.
Topics: Animals; Breast Neoplasms; Female; Humans; Infusions, Parenteral; Lung Neoplasms; Male; Melanoma; Mi | 1979 |
Increased monocyte-mediated cytostasis of lymphoid cell lines in breast and lung cancer patients.
Topics: Animals; Antibody-Dependent Cell Cytotoxicity; BCG Vaccine; Breast Neoplasms; Cell Adhesion; Cell Di | 1979 |
Activity of thymidine as a chemotherapeutic agent against human tumor xenografts in nude mice.
Topics: Animals; Antineoplastic Agents; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Humans; Lung Neopl | 1979 |
Advanced stage and early relapse of breast carcinomas associated with high thymidine labeling indices.
Topics: Age Factors; Aged; Breast Neoplasms; DNA, Neoplasm; Female; Humans; Lymphatic Metastasis; Middle Age | 1979 |
Long-term cultivation of human mammary carcionoma: proliferation and differential biochemical properties of the cultured cells.
Topics: Amino Acids; Breast Neoplasms; Carbohydrate Metabolism; Cell Nucleus; Cells, Cultured; Culture Media | 1979 |
Thymidine labeling index and estrogen receptor level in 64 human breast cancers.
Topics: Adenocarcinoma; Adult; Age Factors; Aged; Autoradiography; Breast Neoplasms; Female; Humans; Middle | 1979 |
[Labelling index in breast cancer and in upper respiratory and digestive tract cancer (author's transl)].
Topics: Breast Neoplasms; Digestive System Neoplasms; Female; Humans; Respiratory Tract Neoplasms; Thymidine | 1979 |
[Autoradiographic studies of human breast cancer after transplantation to nu/nu mice (proceedings)].
Topics: Animals; Autoradiography; Breast Neoplasms; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantati | 1977 |
[Synchronization experiments with human tumors (especially breast cancer) after transplantation to nu/nu mice (proceedings)].
Topics: Adult; Animals; Breast Neoplasms; Female; Humans; Mice; Mice, Nude; Middle Aged; Neoplasm Transplant | 1977 |
[Short-term incubation in vitro with precursors of nucleic acids on human primary tumors and metastases of carcinoma of the breast (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cyclophosphamide; Deoxyuridine; Dose-Response Relationship, | 1978 |
Establishment and characterization of three new continuous cell lines derived from human breast carcinomas.
Topics: Breast Neoplasms; Caseins; Cell Division; Cell Line; Chromosome Aberrations; Female; Humans; Kinetic | 1978 |
The response to hormones and anti-hormones of human breast tumour cells grown in continuous culture [proceedings].
Topics: Breast Neoplasms; Cell Division; Cell Line; DNA, Neoplasm; Female; Hormone Antagonists; Hormones; Hu | 1978 |
[Early and late changes in granulocytopoeisis in intermittant adjuvant chemotherapy of breast carcinoma].
Topics: Breast Neoplasms; Cell Division; Colony-Forming Units Assay; Granulocytes; Humans; Thymidine; Time F | 1978 |
Pretherapeutic cytostatic agent sensitivity testing of breast cancer.
Topics: Breast Neoplasms; Cyclophosphamide; Deoxyuridine; Doxorubicin; Drug Resistance; Female; Humans; RNA, | 1978 |
Cell proliferation in normal human breast ducts, fibroadenomas, and other ductal hyperplasias measured by nuclear labeling with tritiated thymidine. Effects of menstrual phase, age, and oral contraceptive hormones.
Topics: Adenofibroma; Adolescent; Adult; Age Factors; Aged; Breast; Breast Neoplasms; Cell Division; Contrac | 1977 |
In vitro responsiveness of human gastric carcinoma to pentagastrin.
Topics: Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; DNA, Neoplasm; Female; Humans; In Vitro Techni | 1977 |
The proliferative patterns of human breast cancer cells in vivo.
Topics: Adult; Aged; Breast Neoplasms; Cell Division; DNA, Neoplasm; Female; Humans; Kinetics; Middle Aged; | 1977 |
Stimulation of DNA synthesis by human placental lactogen or insulin in organ cultures of benign human breast tumors.
Topics: Breast Neoplasms; DNA, Neoplasm; Epithelial Cells; Epithelium; Female; Humans; Insulin; Mitosis; Org | 1977 |
Effects of estrone, estradiol, and estriol on hormone-responsive human breast cancer in long-term tissue culture.
Topics: Binding, Competitive; Breast Neoplasms; Cell Nucleus; Culture Techniques; Cytoplasm; Drug Interactio | 1977 |
Low incidence of estrogen receptor in breast carcinomas with rapid rates of cellular replication.
Topics: Adult; Aged; Breast Neoplasms; Cell Division; Cytoplasm; Estradiol; Estrogens; Female; Humans; Middl | 1977 |
A rapid in vitro labeling index method for predicting response of human solid tumors to chemotherapy.
Topics: Antineoplastic Agents; Autoradiography; Breast Neoplasms; Drug Evaluation; Female; Humans; In Vitro | 1976 |
In vitro determination of tritiated thymidine labeling index (LI). Evaluation of a method utilizing hyperbaric oxygen and observations on the LI of human mammary carcinoma.
Topics: Animals; Breast Neoplasms; DNA, Neoplasm; Female; Histological Techniques; Humans; Hyperbaric Oxygen | 1975 |
An assessment of the effects of hormones on short term organ cultures of human breast carcinomata.
Topics: Breast; Breast Neoplasms; DNA, Neoplasm; Estradiol; Female; Hormones; Humans; Organ Culture Techniqu | 1975 |
[In-vitro testing of the sensitivity of mammary carcinoma cells to cytostatic drugs (author's transl)].
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cyclophosphamide; Female; Humans; In Vitro T | 1975 |
Effect of testosterone and estradiol-17beta on synthesis of DNA, RNA and protein in human breast in organ culture.
Topics: Adenofibroma; Autoradiography; Breast; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Culture Me | 1975 |
The metabolism of 3-H-estradiol-17 beta in human breast cancer in organ culture.
Topics: Adenofibroma; Amino Acids; Breast; Breast Neoplasms; DNA; Estradiol; Estrone; Female; Humans; Mastit | 1975 |
[The effect of cyclophosphamide on tumors in the sensitivity-test (author's transl)].
Topics: Adenocarcinoma; Alkylation; Animals; Breast Neoplasms; Carcinoma 256, Walker; Cell Count; Cell Divis | 1975 |
Tritiated thymidine labeling index of benign and malignant human breast epithelium.
Topics: Adenofibroma; Adolescent; Adult; Autoradiography; Breast Neoplasms; Carcinoma; Culture Techniques; E | 1976 |
Growth inhibitory and antimitogenic activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in T47D human breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cells, Cultured; Growth Substances; Humans; Polychlorina | 1992 |
Polynuclear aromatic hydrocarbon carcinogens as antiestrogens in MCF-7 human breast cancer cells: role of the Ah receptor.
Topics: Breast Neoplasms; Carcinogens; Cell Division; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme Syste | 1992 |
Monoclonal antibodies against the extracellular domain of the erbB-2 receptor function as partial ligand agonists.
Topics: Antibodies, Monoclonal; Blotting, Western; Breast Neoplasms; Flow Cytometry; Humans; Ligands; Phosph | 1992 |
Interaction with basement membrane serves to rapidly distinguish growth and differentiation pattern of normal and malignant human breast epithelial cells.
Topics: Basement Membrane; Breast; Breast Neoplasms; Cell Differentiation; Cell Division; Cells, Cultured; C | 1992 |
Doxorubicin weekly low dose administration: in vitro cytotoxicity generated by the typical pharmacokinetic profile.
Topics: Breast Neoplasms; Cell Survival; Dose-Response Relationship, Drug; Doxorubicin; Drug Administration | 1992 |
Biological characterisation of primary and metachronous lesions in breast cancer patients.
Topics: Breast Neoplasms; Cell Division; Female; Humans; Mitosis; Neoplasm Metastasis; Neoplasm Recurrence, | 1992 |
Fluorimetric DNA assay for cell growth estimation.
Topics: Animals; Breast Neoplasms; Cattle; Cell Division; Cells, Cultured; DNA; DNA, Neoplasm; Fluorometry; | 1992 |
Mapping the cellular distribution of labelled molecules by SIMS microscopy.
Topics: Adenine; Adult; Arginine; Breast Neoplasms; Carbon Radioisotopes; Cells, Cultured; Deuterium; Female | 1992 |
Programmed cell death in an estrogen-independent human breast cancer cell line, MDA-MB-468.
Topics: Breast Neoplasms; Cell Death; Cell Division; Cell Membrane; DNA Damage; DNA, Neoplasm; Female; Floxu | 1992 |
Bombesin and glucocorticoids stimulate human breast cancer cells to produce endothelin, a paracrine mitogen for breast stromal cells.
Topics: Bombesin; Breast; Breast Neoplasms; Cell Line; Cells, Cultured; Cycloheximide; DNA Replication; Dose | 1992 |
Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells.
Topics: beta Carotene; Breast Neoplasms; Carotenoids; Cell Division; Cell Line; Colonic Neoplasms; DNA, Neop | 1992 |
Long-term prognostic significance of thymidine labelling index in primary breast cancer.
Topics: Breast Neoplasms; Female; Follow-Up Studies; Humans; Mitotic Index; Prognosis; Thymidine; Time Facto | 1992 |
Insulin receptor expression and function in human breast cancer cell lines.
Topics: Breast Neoplasms; DNA, Neoplasm; Female; Gene Amplification; Humans; Insulin; Protein-Tyrosine Kinas | 1992 |
Reduction in apoptosis relative to mitosis in histologically normal epithelium accompanies fibrocystic change and carcinoma of the premenopausal human breast.
Topics: Adenofibroma; Adolescent; Adult; Breast; Breast Neoplasms; Cell Death; Epithelial Cells; Epithelium; | 1992 |
[S-phase fraction of benign mastopathies and breast carcinomas].
Topics: Autoradiography; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Female; Fibrocystic Brea | 1991 |
Demonstration of basic fibroblast growth factor high and low affinity binding sites in human breast cancer cell lines.
Topics: Breast Neoplasms; Cell Line; Cell Membrane; DNA Replication; Female; Fibroblast Growth Factor 2; Gro | 1991 |
Thymidine labeling index in breast tumors.
Topics: Autoradiography; Axilla; Breast Diseases; Breast Neoplasms; Cell Nucleus; Female; Humans; Lymph Node | 1990 |
A comparison between bromodeoxyuridine and 3H thymidine labeling in human breast tumors.
Topics: Analysis of Variance; Autoradiography; Breast Neoplasms; Bromodeoxyuridine; Humans; Observer Variati | 1991 |
Evaluation of the cytotoxic mechanisms mediated by the broad-spectrum antitumor alkaloid acronycine and selected semisynthetic derivatives.
Topics: Acronine; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Cycle; Cell Line; Cell Nucleus; Cel | 1992 |
Loss of heterozygosity on chromosome 17p13 in breast carcinomas identifies tumors with high proliferation index.
Topics: Blotting, Southern; Breast Neoplasms; Bromodeoxyuridine; Cell Division; Cell Transformation, Neoplas | 1992 |
Comparing core needle to surgical biopsies in breast cancer for cell kinetic and ploidy studies.
Topics: Biopsy; Biopsy, Needle; Breast Neoplasms; Cell Division; DNA, Neoplasm; Female; Humans; Kinetics; Pl | 1991 |
Comparative studies of steroidogenesis inhibitors (econazole, ketoconazole) on human breast cancer MCF-7 cell proliferation by growth experiments, thymidine incorporation and flow cytometric DNA analysis.
Topics: Breast Neoplasms; Cell Division; DNA, Neoplasm; Drug Screening Assays, Antitumor; Econazole; Flow Cy | 1991 |
Improvement of DNA repair in lymphocytes of breast cancer patients treated with Viscum album extract (Iscador).
Topics: Adult; Aged; Antineoplastic Agents, Phytogenic; Breast Neoplasms; DNA; DNA Repair; Female; Humans; L | 1991 |
Differences in the kinetics of DNA repair in cancer patients and healthy controls.
Topics: Anemia, Aplastic; Breast Neoplasms; DNA Repair; Female; Humans; Hydroxyurea; In Vitro Techniques; Ki | 1991 |
Gonadotropin-releasing hormone analogues inhibit cell proliferation and activate signal transduction pathways in MDA-MB-231 human breast cancer cell line.
Topics: Antineoplastic Agents; Breast Neoplasms; Buserelin; Cell Division; Gonadotropin-Releasing Hormone; H | 1991 |
Phorbol ester and bryostatin effects on growth and the expression of oestrogen responsive and TGF-beta 1 genes in breast tumour cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Bryostatins; Cell Division; Culture Media; Estradiol; Gene | 1991 |
Feasibility and reproducibility of the [3H]-thymidine labelling index in breast cancer. The SICCAB Group for Quality Control of Cell Kinetic Determination.
Topics: Breast Neoplasms; Cell Cycle; Evaluation Studies as Topic; Humans; Reproducibility of Results; Thymi | 1991 |
Cell cycle phase dependence of estrogen and epidermal growth factor (EGF) receptor expression in MCF-7 cells: implications in antiestrogen and EGF cell responsiveness.
Topics: Binding Sites; Breast Neoplasms; Cell Cycle; Epidermal Growth Factor; ErbB Receptors; Estrogen Antag | 1991 |
Regional heterogeneity in breast carcinoma: thymidine labelling index, steroid hormone receptors, DNA ploidy.
Topics: Adult; Aged; Aged, 80 and over; Aging; Aneuploidy; Breast Neoplasms; DNA; Female; Flow Cytometry; Hu | 1991 |
Changes in cell kinetics induced by primary chemotherapy in breast cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Cell Division; Female; | 1991 |
[Cell kinetic investigations in fibrocystic mastopathies and invasive breast carcinomas].
Topics: Adenofibroma; Antigens, Surface; Breast Neoplasms; Cell Division; DNA Replication; Female; Fibrocyst | 1990 |
Chemosensitivity correlation between the primary tumors and simultaneous metastatic lymph nodes of patients evaluated by DNA synthesis inhibition assay.
Topics: Breast Neoplasms; Carbazilquinone; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Doxorubicin; Drug | 1990 |
Influence of hormones on proliferation of ER-positive cells and ER-negative cells of human breast cancer (MCF-7).
Topics: Animals; Autoradiography; Breast Neoplasms; Female; Humans; Immunohistochemistry; Medroxyprogesteron | 1990 |
In vitro sensitivity test of breast cancer cells to hormonal agents in a radionucleotide-incorporation assay.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Drug Screening Assays, Antitumor; Estradiol; Femal | 1990 |
[Activity of the enzymes of DNA metabolism in the blood of patients with breast cancer].
Topics: 5'-Nucleotidase; Adenocarcinoma; Adenocarcinoma, Scirrhous; Adenosine; Adenosine Deaminase; Age Fact | 1990 |
Role of estrogen-induced insulin-like growth factors in the proliferation of human breast cancer cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; DNA Replication; Estradiol; Female; Humans; Insulin-Like | 1990 |
Proliferative activity of primary breast cancer and of synchronous lymph node metastases evaluated by [3H]-thymidine labelling index.
Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Female; Humans; Lymphatic Metastasis; Mitosis; Pr | 1990 |
Biological response of the anti-estrogen ICI 164,384 in human hormone-dependent and hormone-independent mammary cancer cell lines.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; DNA, Neoplasm; Estradiol; Estrogen Antagonis | 1990 |
3H-thymidine-labeling index as a prognostic indicator in node-positive breast cancer.
Topics: Analysis of Variance; Breast Neoplasms; Cell Cycle; Chi-Square Distribution; Female; Follow-Up Studi | 1990 |
Inhibition of human breast cancer cell proliferation in tissue culture by the neuroleptic agents pimozide and thioridazine.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Line; DNA Replication; Estradiol; Femal | 1990 |
Impact of flow cytometry on predicting recurrence and survival in breast cancer patients.
Topics: Analysis of Variance; Aneuploidy; Breast Neoplasms; Bromodeoxyuridine; Carcinoma, Small Cell; Cell C | 1985 |
Transcriptional control of thymidine kinase gene expression by estrogen and antiestrogens in MCF-7 human breast cancer cells.
Topics: Amanitins; Breast Neoplasms; Cell Cycle; Cell Line; DNA; Estradiol; Estrogen Antagonists; Estrogens; | 1986 |
Effects of human interferon and alpha-difluoromethylornithine on T47D cells.
Topics: Breast Neoplasms; Cell Line; DNA; Drug Synergism; Eflornithine; Humans; Interferons; Ornithine Decar | 1986 |
[Demonstration of pyrimidine nucleoside phosphorylases in breast cancer].
Topics: Breast Neoplasms; Chromatography, Ion Exchange; Cytosol; Humans; Pentosyltransferases; Pyrimidine Ph | 1989 |
[Intracellular localization of halogenated drugs or molecules in cultured tumor cells. A study using ionic microscopy associated with an imaging processing system].
Topics: Breast Neoplasms; Bromodeoxyuridine; Cells, Cultured; Female; Floxuridine; Humans; Image Processing, | 1989 |
Thymidine labeling index and Ki-67 growth fraction in lesions of the breast.
Topics: Antibodies, Monoclonal; Breast Diseases; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; | 1989 |
Factors affecting relapse in node-negative breast cancer. A multivariate analysis including the labeling index.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Breast Neoplasms; DNA, Neoplasm; Female; Humans; Lympha | 1989 |
Differential estrogenic responsiveness of MCF-7 cells. Relationship to the presence of two different estrogen receptors.
Topics: Breast Neoplasms; Cell Count; Estradiol; Female; Humans; Molecular Weight; Receptors, Estrogen; Rece | 1989 |
Expression of platelet-derived growth factor (PDGF)-related transcripts and synthesis of biologically active PDGF-like proteins by human malignant epithelial cell lines.
Topics: Binding, Competitive; Breast Neoplasms; Carcinoma; Cell Line; Colonic Neoplasms; Epithelium; Female; | 1988 |
Interleukin-1 directly regulates hormone-dependent human breast cancer cell proliferation in vitro.
Topics: Binding, Competitive; Breast Neoplasms; Cell Division; Female; Humans; Interleukin-1; Isotope Labeli | 1988 |
A comparison of human breast cancer cell kinetics measured by flow cytometry and thymidine labeling.
Topics: Breast Neoplasms; Carcinoma; Carcinoma, Intraductal, Noninfiltrating; Cell Cycle; Cell Movement; Fem | 1985 |
Transferrin receptors in cultured breast cancer cells.
Topics: Breast Neoplasms; Cells, Cultured; DNA, Neoplasm; Female; Humans; Receptors, Cell Surface; Receptors | 1985 |
Cell kinetics of histologic variants of in situ breast carcinoma.
Topics: Adult; Aged; Biopsy; Breast Neoplasms; Carcinoma in Situ; Carcinoma, Intraductal, Noninfiltrating; C | 1986 |
Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines.
Topics: Breast Neoplasms; Cell Line; Culture Media; Humans; Molecular Weight; Platelet-Derived Growth Factor | 1987 |
Prognostic value of continuous variables in breast cancer and head and neck cancer. Dependence on the cut-off level.
Topics: Breast Neoplasms; Female; Head and Neck Neoplasms; Humans; Interphase; Mitosis; Predictive Value of | 1988 |
Proliferative index of breast carcinoma by thymidine labeling: prognostic power independent of stage, estrogen and progesterone receptors.
Topics: Breast Neoplasms; Cell Division; Humans; Middle Aged; Neoplasm Staging; Prognosis; Receptors, Estrog | 1988 |
Cell kinetics, growth rate and the natural history of breast cancer. The Heuson Memorial Lecture.
Topics: Breast Neoplasms; Cell Division; DNA, Neoplasm; Female; Humans; Interphase; Lymph Nodes; Lymphatic M | 1988 |
Thymidine labeling index, flow cytometric S-phase measurement, and DNA index in human tumors. Comparisons and correlations.
Topics: Breast Neoplasms; DNA, Neoplasm; Flow Cytometry; Humans; Interphase; Neoplasms; Ploidies; Prognosis; | 1988 |
Determination of DNA synthesis, estrogen receptors, and carcinoembryonic antigen in isolated cellular subpopulations of human breast cancer.
Topics: Adenocarcinoma; Aged; Breast Neoplasms; Carcinoembryonic Antigen; Cell Separation; Cells, Cultured; | 1986 |
[Utilization of the TLI technic (thymidine labeling index) in cancerology].
Topics: Animals; Breast Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Mice; Neoplasms; Neoplas | 1987 |
Mode of estrogen action on cell proliferation in CAMA-1 cells: II. Sensitivity of G1 phase population.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; Cell Line; Estradiol; Humans; Interphase; Kinetics; Neo | 1987 |
Reduced DNA repair synthesis in healthy women having first degree relatives with breast cancer.
Topics: Adult; Aged; Breast Neoplasms; DNA Repair; Female; Humans; Hydroxyurea; Menopause; Middle Aged; Risk | 1987 |
Counting and sampling errors: (mis)interpretation of data from tritiated thymidine labelled human tumors.
Topics: Breast Neoplasms; Humans; Radiometry; Statistics as Topic; Thymidine; Tritium | 1987 |
1,25-Dihydroxyvitamin D3 inhibitory effect on the growth of two human breast cancer cell lines (MCF-7, BT-20).
Topics: Breast Neoplasms; Calcitriol; Cell Line; Culture Media; Dose-Response Relationship, Drug; Female; Fl | 1986 |
Cytokinetic parameters of locally advanced human breast cancer treated with diethylstilbestrol and chemotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cell Cycle; Cyclophosphamide; Diet | 1986 |
Tritiated thymidine labelling in vitro of human cancer of the breast: counting error and sampling error.
Topics: Breast Neoplasms; Cell Count; Female; Humans; In Vitro Techniques; Thymidine; Tritium | 1986 |
Impaired DNA-repair synthesis in lymphocytes of breast cancer patients.
Topics: Adult; Aged; Breast Neoplasms; DNA; DNA Repair; Female; Humans; Hydroxyurea; Lymphocytes; Middle Age | 1986 |
Cell kinetics in selection and stratification of patients for adjuvant therapy of breast carcinoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Carcinoma in Situ; Cell Cy | 1986 |
Prognostic implication of labeling index versus estrogen receptors and tumor size in node-negative breast cancer.
Topics: Axilla; Breast Neoplasms; Female; Follow-Up Studies; Humans; Lymph Nodes; Mastectomy; Menopause; Mid | 1986 |
Proliferative activity of human solid tumors evaluated by thymidine labeling index and primer-dependent alpha-DNA polymerase.
Topics: Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cell Division; DNA Polymerase II; Female; Head and | 1986 |
Emerging impact of flow cytometry in predicting recurrence and survival in breast cancer patients.
Topics: Breast Neoplasms; Cell Cycle; Cell Division; DNA, Neoplasm; Female; Flow Cytometry; Humans; Neoplasm | 1985 |
Interaction of estradiol and high density lipoproteins on proliferation of the human breast cancer cell line MCF-7 adapted to grow in serum free conditions.
Topics: Breast Neoplasms; Cell Count; Cell Division; Cell Line; Culture Media; Drug Interactions; Estradiol; | 1985 |
Breast carcinoma cell kinetics, morphology, stage, and host characteristics. A thymidine labeling study.
Topics: Adolescent; Adult; Aged; Breast Neoplasms; Cell Cycle; Estradiol; Female; Humans; Lymph Nodes; Middl | 1986 |
A proposed classification of breast cancer based on kinetic information: derived from a comparison of risk factors in 168 primary operable breast cancers.
Topics: Breast Neoplasms; Cell Cycle; Female; Flow Cytometry; Humans; Ploidies; Receptors, Estrogen; Recepto | 1986 |
Reliability and stability of the thymidine labeling index of breast carcinoma.
Topics: Biopsy; Breast Neoplasms; Carcinoma; Humans; Mastectomy; Mathematics; Neoplasm Recurrence, Local; Ne | 1986 |
In vitro thymidine labelling index in primary operable breast cancer.
Topics: Autoradiography; Breast Neoplasms; Carcinoma; DNA, Neoplasm; Female; Follow-Up Studies; Humans; Mast | 1986 |
Effect of estrogens and antiestrogens on growth-regulatory enzymes in human breast cancer cells in tissue culture.
Topics: Breast Neoplasms; Cell Cycle; Cells, Cultured; DNA, Neoplasm; Estrogen Antagonists; Estrogens; Femal | 1985 |
Oestradiol is effective in stimulating 3H-thymidine incorporation but not on proliferation of breast cancer cultured cells.
Topics: Breast Neoplasms; Cell Division; Cell Line; Cell Nucleus; DNA Replication; Estradiol; Female; Flow C | 1985 |
Significance of the Tritiated Thymidine Labeling Index in breast cancers.
Topics: Binding Sites; Breast Neoplasms; Female; Humans; Middle Aged; Receptors, Estrogen; Receptors, Proges | 1985 |
Chemotherapy following estrogen-induced expansion of the growth fraction of human breast cancer.
Topics: Adult; Aged; Breast Neoplasms; Cell Division; Diethylstilbestrol; Female; Humans; Middle Aged; Recep | 1985 |
Influence of phomopsin and ivalin on steroid-hormone binding and growth of MCF-7 human breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Division; Cell Survival; Cells, Cultured; Dexamethason | 1985 |
In vitro activity of alkylating agents on human tumors as measured by a short-term antimetabolic assay.
Topics: Alkylating Agents; Breast Neoplasms; Cells, Cultured; DNA, Neoplasm; Drug Evaluation, Preclinical; E | 1985 |
Estrogen induced expansion of the growth fraction in receptor negative human breast cancer.
Topics: Breast Neoplasms; Cell Division; Cyclophosphamide; Diethylstilbestrol; DNA Polymerase II; DNA Replic | 1985 |
Hormone assays on breast-tumour cultures.
Topics: Adenocarcinoma, Scirrhous; Adenofibroma; Autoradiography; Breast Neoplasms; Carbon Radioisotopes; Ca | 1973 |
Effect of radiation treatment on cell-mediated immune response in carcinoma of the breast.
Topics: Aged; Blood Transfusion; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Cobalt Radioisotopes; Fe | 1974 |
Blood lymphocytes after radiation therapy of mammary carcinoma.
Topics: Aged; Animals; Blood Cell Count; Breast Neoplasms; Carbon Radioisotopes; Cell Membrane; Cells, Cultu | 1974 |
[Clinical experiences with a combination therapy of metastasising genital and mammary carcinomas (author's transl)].
Topics: Adult; Aged; Breast Neoplasms; Carcinoma; Cyclophosphamide; Cytidine; Drug Therapy, Combination; Fem | 1974 |
Phase I and II studies of 2'-deoxy-5-(trifluoromethyl)-uridine (NSC-75520).
Topics: Blood Cell Count; Bone Marrow; Breast Neoplasms; Colonic Neoplasms; Deoxyuridine; Female; Floxuridin | 1971 |
Lymphocyte stimulation by phytohemagglutinin and tumor cells of malignant effusions.
Topics: Antigens, Neoplasm; Ascitic Fluid; Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; Female; Hum | 1974 |
Cytostatic effects of G-6-PDH inhibitors in cell cultures from normal and neoplastic tissue.
Topics: Breast Neoplasms; Cells, Cultured; Dehydroepiandrosterone; DNA; Female; Glucosephosphate Dehydrogena | 1974 |
DNA replication and degradation in mammalian tissues. V. A series of slow-growing rat renal tumors and a variety of human cancers.
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Col | 1969 |
Activation of host lymphocytes cultured with cancer cells treated with neuraminidase.
Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Colonic Neoplasms; Culture Tec | 1971 |
Human carcinoma of the breast, in vitro: the effect of hormones. A prelininary report.
Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Chorionic Gonadotropin; Cult | 1971 |
Lymphocyte blastogenic responses to cultured allogeneic tumor cells in vitro.
Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Count; Cells, Cultured; Female; Hu | 1972 |
Endocrine and immunologic studies in breast cancer.
Topics: Adrenalectomy; Adult; Binding, Competitive; Breast Neoplasms; Castration; Drug Hypersensitivity; Est | 1973 |
Lymphoid cells in carcinoma of the breast. Failure of response to phytohaemagglutinin in vitro.
Topics: Adenocarcinoma, Scirrhous; Adult; Breast Neoplasms; Carbon Radioisotopes; Carcinoma; Cells, Cultured | 1973 |
Growth quantitation of human mammary carcinoma in organ tissue culture.
Topics: Adenocarcinoma, Scirrhous; Analysis of Variance; Autoradiography; Breast Neoplasms; Carcinoma, Intra | 1974 |
In vitro assay for human breast cancer hormone responsiveness. A study of 25 cases with clinical correlation.
Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Adult; Aged; Animals; Breast Neoplasms; Carcinoma; Carcin | 1974 |
Kinetics of human mammary carcinomas and their correlation with the cancer and the host characteristics.
Topics: Adult; Age Factors; Aged; Biopsy; Breast Neoplasms; Carbon Radioisotopes; Cell Division; Cell Surviv | 1974 |
In vitro estimate of sensitivity of individual human tumors to antitumor agents.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Arsenicals; Benzoates; Breast Neoplasms; Carbon Radi | 1974 |
Antigen solubilized from human solid tumours: lymphocyte stimulation and cutaneous delayed hypersensitivity.
Topics: Antigens, Neoplasm; Breast Neoplasms; Carcinoma; Colonic Neoplasms; Female; Hodgkin Disease; Humans; | 1973 |
Detection and isolation of a new DNA polymerase from human breast tumor cell line HBT-3 by (dT)12-18-cellulose chromatography.
Topics: Adenine Nucleotides; Breast Neoplasms; Cell Line; Cellulose; Centrifugation, Density Gradient; Chrom | 1973 |
Peripheral blood lymphocytes and breast cancer.
Topics: Adult; Age Factors; Breast Neoplasms; Carcinoma; Female; Humans; Leukocyte Count; Lymphocyte Activat | 1973 |
Depression of lymphocyte replicating ability in radiotherapy patients.
Topics: Autoradiography; Breast Neoplasms; Carcinoma, Squamous Cell; Chromosomes; Dysgerminoma; Female; Huma | 1974 |
Impaired cell-mediated immunity in patients with cancer.
Topics: Breast Neoplasms; Cells, Cultured; Gastrointestinal Neoplasms; Humans; Immunity, Cellular; Lectins; | 1974 |
Effect of postoperative radiotherapy on peripheral blood lymphocytes in patients with carcinoma of the breast.
Topics: Adult; Aged; Breast Neoplasms; Cobalt Isotopes; Culture Techniques; DNA; Female; Humans; Immunity, C | 1972 |
[Change in peripheral blood lymphocytes with radiotherapy].
Topics: Adult; Breast Neoplasms; Choriocarcinoma; Female; Humans; Lectins; Leukocytes; Lymphocyte Activation | 1972 |
In vitro and in vivo labelling of animal tumours with tritiated thymidine.
Topics: Animals; Breast Neoplasms; Carcinoma; Fibrosarcoma; Hyperbaric Oxygenation; Isotope Labeling; Lympho | 1973 |
Effect of hormones on DNA synthesis in explants from rat and human breast cancers.
Topics: Animals; Breast Neoplasms; DNA, Neoplasm; Female; Hormones; Humans; Insulin; Isoenzymes; L-Lactate D | 1973 |
The response to phytohaemagglutinin (PHA) of lymphocytes from cancer patients.
Topics: Breast Neoplasms; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lectins; Leukemia; Lymph | 1973 |
Sensitivity tests on human cancers to select active drugs for clinical cancer therapy.
Topics: Agar; Animals; Antineoplastic Agents; Arsenicals; Breast Neoplasms; Cell Survival; Depression, Chemi | 1973 |
Studies concerning the regional lymph node in cancer. VII. Thymidine uptake by cells from nodes of breast cancer patients relative to axillary location and histopathologic discriminants.
Topics: Axilla; Breast Neoplasms; Female; Histiocytes; Humans; Lymph Node Excision; Lymph Nodes; Lymphocytes | 1974 |
Human mammary carcinoma studied for hormone responsiveness in short term incubations.
Topics: Androsterone; Breast Neoplasms; Depression, Chemical; DNA, Neoplasm; Dose-Response Relationship, Dru | 1974 |
[DNS synthesizing lymphocytes in patients with carcinoma].
Topics: Autoradiography; Blood Cell Count; Breast Neoplasms; Bronchial Neoplasms; DNA, Neoplasm; Female; His | 1971 |
Response of DNA thymine synthesis in human tumor and normal tissue to 5-fluorouracil.
Topics: Breast Neoplasms; Carbon Isotopes; Chromatography, Paper; Colon; Colonic Neoplasms; Depression, Chem | 1972 |
Studies concerning the regional lymph node in cancer. 3. Response of regional lymph node cells from breast and colon cancer patients to PHA stimulation.
Topics: Adolescent; Adult; Aged; Breast Diseases; Breast Neoplasms; Cells, Cultured; Colonic Neoplasms; Fema | 1972 |
Depressed lymphocyte function in carcinoma of the breast.
Topics: Breast Neoplasms; Female; Humans; Lectins; Lymphocyte Activation; Lymphocytes; Neoplasm Recurrence, | 1971 |
A study on hormone dependency of breast cancer.
Topics: Adrenalectomy; Adult; Animals; Autoradiography; Breast Neoplasms; Castration; DNA, Neoplasm; Estradi | 1971 |
Blood lymphocyte replicating ability as a measurement of radiation dosage.
Topics: Aged; Blood Vessels; Breast Neoplasms; Bronchial Neoplasms; Cell Division; Cells, Cultured; Female; | 1971 |
Analysis of the cell kinetics of human solid tumors.
Topics: Adult; Aged; Biopsy; Bone Neoplasms; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Colo | 1971 |
Cytotoxic penetration and concentration in human malignant tumours.
Topics: Antineoplastic Agents; Breast Neoplasms; Colonic Neoplasms; Female; Fluorouracil; Humans; Injections | 1969 |
Cell cycle characteristics of human solid tumors in vivo.
Topics: Biopsy; Breast Neoplasms; Cell Count; Cell Differentiation; DNA; DNA, Neoplasm; Humans; Kinetics; Me | 1970 |
The use of selected sulfhydryl inhibitors in a preferential drug attack on cancer.
Topics: Adenocarcinoma; Adult; Agar; Animals; Antineoplastic Agents; Anus Neoplasms; Breast Neoplasms; Carci | 1971 |