thymidine has been researched along with Brain Neoplasms in 119 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This phase II study in recurrent high-grade glioma evaluated the response rate, toxicities, and time to treatment failure of high-dose carboplatin modulated by a 24-h infusion of thymidine (75 g/m(2))." | 9.10 | A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study. ( Chang, SM; Cloughesy, T; Fink, K; Greenberg, H; Hess, K; Junck, L; Kuhn, JG; Mehta, M; Nicolas, K; Prados, MD; Robins, HI; Schiff, D; Yung, WK, 2002) |
| " The purpose of this study was to evaluate (11)C-4DST uptake in patients with newly diagnosed glioma and to correlate the results with proliferative activity and tumor grade, in comparison with L-[methyl-(11)C]-methionine ((11)C-MET)." | 7.83 | Correlation of 4'-[methyl-(11)C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with (11)C-methionine uptake. ( Kawai, N; Kudomi, N; Maeda, Y; Nishiyama, Y; Tanaka, K; Toyohara, J; Yamamoto, H; Yamamoto, Y, 2016) |
| "The effect of genistein, a protein tyrosine kinase and topoisomerase II inhibitor, on the DNA synthesis rate was studied in 21 human glioma specimens obtained at routine craniotomies for tumor resection." | 7.75 | Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein. ( Cruz, MH; Ohlsson Lindblom, I; Siden, A; Yakisich, JS, 2009) |
| "The authors have previously shown that medroxyprogesterone acetate (MPA) inhibits growth and increases drug sensitivity in C6 glioma with myeloid bodies." | 7.74 | Medroxyprogesterone acetate induces c6 glioma chemosensitization via antidepressant-like lysosomal phospholipidosis/myelinosis in vitro. ( Altinoz, MA; Bilir, A; Del Maestro, RF; Gedikoglu, G; Ozcan, E; Ozdilli, K; Sav, A, 2007) |
| " This study examines the predictive value of positron emission tomography (PET) using [18F] fluorothymidine (FLT), an imaging biomarker of cell proliferation, in patients with recurrent malignant gliomas treated with bevacizumab in combination with irinotecan." | 7.74 | Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study. ( Chen, W; Cloughesy, T; Czernin, J; Delaloye, S; Geist, C; Lai, A; Phelps, ME; Pope, W; Satyamurthy, N; Sayre, J; Silverman, DH, 2007) |
| ") injection of radio-iododeoxyuridine (IdUrd), a thymidine (dThd) analogue, is envisaged for targeted Auger electron- or beta-radiation therapy of glioblastoma." | 7.72 | Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts. ( Adamer, F; Buchegger, F; de Tribolet, N; Delaloye, AB; Dupertuis, YM; Grannavel, C; Kosinski, M; Mach, JP; Schaffland, AO, 2004) |
| "In human astrocytoma U373 MG cells that express histamine H1 receptors (180 +/- 6 fmol/mg protein) but not H2 or H3 receptors, histamine stimulated mitogenesis as assessed by [3H]-thymidine incorporation (173 +/- 2% of basal; EC50, 2." | 7.71 | Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells. ( Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE, 2001) |
| "We have recently shown that endothelin-1 activates two types of Ca2+-permeable nonselective cation channels (NSCC-1 and NSCC-2) in C6 glioma cells." | 7.71 | Effects of extracellular Ca2+ influx on endothelin-1-induced intracellular mitogenic cascades in C6 glioma cells. ( Hashimoto, N; Kawanabe, Y; Masaki, T, 2002) |
| "The combination of lonidamine and diazepam--drugs that target two distinct mitochondrial sites involved in cellular energy metabolism--potentiates the effects of the individual drugs and may prove useful in the treatment of human glioblastomas." | 7.70 | Potentiation of lonidamine and diazepam, two agents acting on mitochondria, in human glioblastoma treatment. ( Bourgeois, Y; Bras Gonçalves, R; Dutrillaux, B; Miccoli, L; Oudard, S; Poirson-Bichat, F; Poupon, MF; Sureau, F, 1998) |
| "Treatment of rat C6 glioma cells with the tricyclic antidepressant desipramine induces opioid binding." | 7.69 | A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA. ( Barg, J; Belcheva, MM; Coscia, CJ; Johnson, FE; Levy, R; McHale, RJ; McLachlan, JA; Vogel, Z, 1994) |
| "The growth of human cerebral meningiomas depends on various growth factors, including epidermal growth factor (EGF), transforming growth factor (TGF)-alpha and TGF-beta, platelet-derived growth factor (PDGF)-BB, insulin-like growth factor (IGF)-I and IGF-II, and acidic and basic fibroblast growth factors." | 7.69 | Inhibition of proliferation of human cerebral meningioma cells by suramin: effects on cell growth, cell cycle phases, extracellular growth factors, and PDGF-BB autocrine growth loop. ( Adams, EF; Bickel, A; Fahlbusch, R; Gauer, S; Hren, J; Kiesewetter, F; Schrell, UM, 1995) |
| "The antiviral agents ganciclovir, 1-beta-D-arabinofuranosylthymine (araT), acyclovir, and 5-iodo-5'-amino-2',5'-dideoxyuridine were cytotoxic to rat C6 glioma cells expressing retrovirally transferred herpes simplex virus (HSV) type 1 thymidine kinase (TK) coding sequence, with concentrations that inhibited cell survival by 50% (IC50 values) of 0." | 7.69 | Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells. ( Breakefield, XO; Davidson, BL; Hughes, TL; Roessler, BJ; Shewach, DS; Zerbe, LK, 1994) |
| " The mitogenic properties of epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) were examined in three human malignant glioma cell lines (T98G, U87, and U138)." | 7.68 | Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium. ( Kelly, RH; Kristofik, MP; Pollack, IF; Randall, MS; Selker, RG; Vertosick, FT, 1990) |
| "Cholecystokinin (CCK) is a gut-brain peptide has been described to be able to induce mitosis according to recent studies." | 5.35 | Cholecystokinin (CCK) and CCK receptor expression by human gliomas: Evidence for an autocrine/paracrine stimulatory loop. ( Adams, EF; Buchfelder, M; Oikonomou, E, 2008) |
| "This phase II study in recurrent high-grade glioma evaluated the response rate, toxicities, and time to treatment failure of high-dose carboplatin modulated by a 24-h infusion of thymidine (75 g/m(2))." | 5.10 | A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study. ( Chang, SM; Cloughesy, T; Fink, K; Greenberg, H; Hess, K; Junck, L; Kuhn, JG; Mehta, M; Nicolas, K; Prados, MD; Robins, HI; Schiff, D; Yung, WK, 2002) |
| " The killing of cells and apparent beneficial effect of tritiated thymidine in human leukemia are described." | 4.76 | Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia? ( Cronkite, EP; Fairchild, RG; Miller, ME, 1983) |
| " The purpose of this study was to evaluate (11)C-4DST uptake in patients with newly diagnosed glioma and to correlate the results with proliferative activity and tumor grade, in comparison with L-[methyl-(11)C]-methionine ((11)C-MET)." | 3.83 | Correlation of 4'-[methyl-(11)C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with (11)C-methionine uptake. ( Kawai, N; Kudomi, N; Maeda, Y; Nishiyama, Y; Tanaka, K; Toyohara, J; Yamamoto, H; Yamamoto, Y, 2016) |
| "The effect of genistein, a protein tyrosine kinase and topoisomerase II inhibitor, on the DNA synthesis rate was studied in 21 human glioma specimens obtained at routine craniotomies for tumor resection." | 3.75 | Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein. ( Cruz, MH; Ohlsson Lindblom, I; Siden, A; Yakisich, JS, 2009) |
| "The authors have previously shown that medroxyprogesterone acetate (MPA) inhibits growth and increases drug sensitivity in C6 glioma with myeloid bodies." | 3.74 | Medroxyprogesterone acetate induces c6 glioma chemosensitization via antidepressant-like lysosomal phospholipidosis/myelinosis in vitro. ( Altinoz, MA; Bilir, A; Del Maestro, RF; Gedikoglu, G; Ozcan, E; Ozdilli, K; Sav, A, 2007) |
| "Intoxication due to insufficient renal clearance developed in 2 patients, a 54-year-old man and a 61-year-old woman, who were under treatment with methotrexate (MTX) for a primary cerebral lymphoma and a recurrence of large-cell B-cell-non-Hodgkin lymphoma, respectively." | 3.74 | [Management recommendations in patients with methotrexate intoxication]. ( Beijnen, JH; Schellens, JH, 2007) |
| " This study examines the predictive value of positron emission tomography (PET) using [18F] fluorothymidine (FLT), an imaging biomarker of cell proliferation, in patients with recurrent malignant gliomas treated with bevacizumab in combination with irinotecan." | 3.74 | Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study. ( Chen, W; Cloughesy, T; Czernin, J; Delaloye, S; Geist, C; Lai, A; Phelps, ME; Pope, W; Satyamurthy, N; Sayre, J; Silverman, DH, 2007) |
| " The human glioma cell lines U87 MG, U251 MG and U138 MG were treated with purines and pyrimidines for 24 or 48 h and proliferation was measured by [3H]-thymidine incorporation, flow cytometry and cell counting." | 3.72 | Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines. ( Bernardi, A; Horn, AP; Jacques-Silva, MC; Lenz, G; Morrone, FB; Rodnight, R; Schwartsmann, G, 2003) |
| ") injection of radio-iododeoxyuridine (IdUrd), a thymidine (dThd) analogue, is envisaged for targeted Auger electron- or beta-radiation therapy of glioblastoma." | 3.72 | Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts. ( Adamer, F; Buchegger, F; de Tribolet, N; Delaloye, AB; Dupertuis, YM; Grannavel, C; Kosinski, M; Mach, JP; Schaffland, AO, 2004) |
| "We have recently shown that endothelin-1 activates two types of Ca2+-permeable nonselective cation channels (NSCC-1 and NSCC-2) in C6 glioma cells." | 3.71 | Effects of extracellular Ca2+ influx on endothelin-1-induced intracellular mitogenic cascades in C6 glioma cells. ( Hashimoto, N; Kawanabe, Y; Masaki, T, 2002) |
| "In human astrocytoma U373 MG cells that express histamine H1 receptors (180 +/- 6 fmol/mg protein) but not H2 or H3 receptors, histamine stimulated mitogenesis as assessed by [3H]-thymidine incorporation (173 +/- 2% of basal; EC50, 2." | 3.71 | Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells. ( Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE, 2001) |
| "A 54-year-old patient with primary cerebral lymphoma was treated with two 4-weekly cycles of high-dose intravenous cytarabine (12 g/m2) and methotrexate (3 g/m2)." | 3.71 | Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure. ( Beijnen, JH; Boogerd, W; Mathĵt, RA; Schellens, JH; Schornagel, JH; Soesan, M; van den Bongard, HJ, 2001) |
| "The combination of lonidamine and diazepam--drugs that target two distinct mitochondrial sites involved in cellular energy metabolism--potentiates the effects of the individual drugs and may prove useful in the treatment of human glioblastomas." | 3.70 | Potentiation of lonidamine and diazepam, two agents acting on mitochondria, in human glioblastoma treatment. ( Bourgeois, Y; Bras Gonçalves, R; Dutrillaux, B; Miccoli, L; Oudard, S; Poirson-Bichat, F; Poupon, MF; Sureau, F, 1998) |
| "The growth of human cerebral meningiomas depends on various growth factors, including epidermal growth factor (EGF), transforming growth factor (TGF)-alpha and TGF-beta, platelet-derived growth factor (PDGF)-BB, insulin-like growth factor (IGF)-I and IGF-II, and acidic and basic fibroblast growth factors." | 3.69 | Inhibition of proliferation of human cerebral meningioma cells by suramin: effects on cell growth, cell cycle phases, extracellular growth factors, and PDGF-BB autocrine growth loop. ( Adams, EF; Bickel, A; Fahlbusch, R; Gauer, S; Hren, J; Kiesewetter, F; Schrell, UM, 1995) |
| "The antiviral agents ganciclovir, 1-beta-D-arabinofuranosylthymine (araT), acyclovir, and 5-iodo-5'-amino-2',5'-dideoxyuridine were cytotoxic to rat C6 glioma cells expressing retrovirally transferred herpes simplex virus (HSV) type 1 thymidine kinase (TK) coding sequence, with concentrations that inhibited cell survival by 50% (IC50 values) of 0." | 3.69 | Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells. ( Breakefield, XO; Davidson, BL; Hughes, TL; Roessler, BJ; Shewach, DS; Zerbe, LK, 1994) |
| "Treatment of rat C6 glioma cells with the tricyclic antidepressant desipramine induces opioid binding." | 3.69 | A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA. ( Barg, J; Belcheva, MM; Coscia, CJ; Johnson, FE; Levy, R; McHale, RJ; McLachlan, JA; Vogel, Z, 1994) |
| "A series of laboratory investigations were used to demonstrate antiproliferative effects (MTT assay, colony forming assay, thymidine incorporation), cell cycle synchronization (flow cytometry), intracellular localization of binding sites (immunocytochemistry, electron microscopy), and activity in subcutaneous xenografts of human glioblastoma." | 3.69 | Targeting microtubule-associated proteins in glioblastoma: a new strategy for selective therapy. ( Greer, C; Pedersen, PE; Piepmeier, JM; Yoshida, D, 1996) |
| "In the present study the effect of cocaine on thymidine, uridine and leucine incorporation was assessed in primary cortical glial and C6 glioma cells." | 3.68 | Effect of cocaine on macromolecular syntheses and cell proliferation in cultured glial cells. ( Bansinath, M; Garg, UC; Turndorf, H, 1993) |
| " The mitogenic properties of epidermal growth factor (EGF) and platelet-derived growth factor (PDGF) were examined in three human malignant glioma cell lines (T98G, U87, and U138)." | 3.68 | Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium. ( Kelly, RH; Kristofik, MP; Pollack, IF; Randall, MS; Selker, RG; Vertosick, FT, 1990) |
| " The potential proliferative activity of these different neoplasms, evaluated as in vitro 3H-thymidine labeling index (LI), has been determined in 46 mature astrocytomas, 19 anaplasic astrocytomas, 25 glioblastomas, 5 cystic craniopharyngiomas, 6 metastatic tumors, 4 primary C." | 3.67 | Cell kinetic investigations in brain tumors studied by serial stereotactic biopsy. ( Allegranza, A; Broggi, G; Costa, A; Ferraresi, S; Franzini, A; Giorgi, C, 1989) |
| "Twelve patients with gliomas received 3H-thymidine intraarterially in combination with an i." | 3.66 | The stathmokinetic (mitostatic) effect of vincristine and vinblastine on human gliomas. ( Hoshino, T; Muraoka, I; Wilson, CB, 1979) |
| "Tritiated thymidine (3-H-T) was administered intravenously to seven patients with cerebral gliomas." | 3.65 | Gemistocytic astrocytes in gliomas. An autoradiographic study. ( Ellis, WG; Hoshino, T; Wilson, BC, 1975) |
| "Malignant brain tumors pose diagnostic and therapeutic problems." | 2.69 | 2-[C-11]thymidine imaging of malignant brain tumors. ( Berger, MS; Eary, JF; Krohn, KA; Link, JM; Mankoff, DA; O'Sullivan, F; Olshen, A; Spence, AM, 1999) |
| "Neuroblastoma is an embryonic tumor derived from cells of the neural crest." | 1.39 | LMO4 is an essential cofactor in the Snail2-mediated epithelial-to-mesenchymal transition of neuroblastoma and neural crest cells. ( de Torres, C; Ferronha, T; Gil-Guiñon, E; Le Dréau, G; Martí, E; Rabadán, MA, 2013) |
| "Cholecystokinin (CCK) is a gut-brain peptide has been described to be able to induce mitosis according to recent studies." | 1.35 | Cholecystokinin (CCK) and CCK receptor expression by human gliomas: Evidence for an autocrine/paracrine stimulatory loop. ( Adams, EF; Buchfelder, M; Oikonomou, E, 2008) |
| "Interestingly, OSM did not suppress astroglioma cell invasion." | 1.33 | Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases. ( Benveniste, EN; Chen, SH; Gillespie, GY, 2006) |
| "We studied brain tumors induced by avian sarcoma virus and ethylnitrosourea, and transplanted RG-2 intracerebral and subcutaneous gliomas." | 1.27 | Regional thymidine transport and incorporation in experimental brain and subcutaneous tumors. ( Blasberg, R; Fenstermacher, J; Groothuis, D; Molnar, P; Owens, E; Zaharko, D, 1984) |
| "Patients with malignant brain tumors have a variety of immunologic abnormalities, including the impaired responsiveness of peripheral blood lymphocytes (PBL) to mitogens and alloantigens." | 1.27 | Cytokinetic basis for the impaired activation of lymphocytes from patients with primary intracranial tumors. ( Brooks, WH; Elliott, LH; Roszman, TL, 1984) |
| "Nuclei isolated by grinding 9L rat brain tumors gave a DNA distribution consisting of a 2C DNA peak due to noncycling normal cells and a bimodal distribution beginning at about 4C DNA due to the cycling tumor cells." | 1.26 | Flow cytometry of isolated nuclei prepared from 9L rat brain tumor. ( Gray, JW; Hoshino, T; Nomura, K, 1979) |
| "Referring to the results of various brain tumors reported in the literature, this belongs to the highest labeling group." | 1.25 | 3H-thymidine autoradiography of CSF cells in primary reticulum cell sarcoma of the brain. ( Fukui, M; Kitamura, K; Tabira, T; Yamakawa, Y; Yamasaki, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 54 (45.38) | 18.7374 |
| 1990's | 27 (22.69) | 18.2507 |
| 2000's | 30 (25.21) | 29.6817 |
| 2010's | 8 (6.72) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferronha, T | 1 |
| Rabadán, MA | 1 |
| Gil-Guiñon, E | 1 |
| Le Dréau, G | 1 |
| de Torres, C | 1 |
| Martí, E | 1 |
| Barth, RF | 4 |
| Yang, W | 4 |
| Nakkula, RJ | 1 |
| Byun, Y | 4 |
| Tjarks, W | 5 |
| Wu, LC | 1 |
| Binns, PJ | 2 |
| Riley, KJ | 2 |
| Tanaka, K | 1 |
| Yamamoto, Y | 1 |
| Maeda, Y | 1 |
| Yamamoto, H | 1 |
| Kudomi, N | 1 |
| Kawai, N | 1 |
| Toyohara, J | 1 |
| Nishiyama, Y | 1 |
| Laks, DR | 1 |
| Ta, L | 1 |
| Crisman, TJ | 1 |
| Gao, F | 1 |
| Coppola, G | 1 |
| Radu, CG | 1 |
| Nathanson, DA | 1 |
| Kornblum, HI | 1 |
| Wu, G | 1 |
| Swindall, M | 1 |
| Narayanasamy, S | 1 |
| Tordoff, K | 1 |
| Moeschberger, ML | 1 |
| Eriksson, S | 3 |
| Yakisich, JS | 1 |
| Ohlsson Lindblom, I | 1 |
| Siden, A | 1 |
| Cruz, MH | 1 |
| Bagriacik, EU | 1 |
| Baykaner, MK | 1 |
| Yaman, M | 1 |
| Sivrikaya, G | 1 |
| Durdağ, E | 1 |
| Emmez, H | 1 |
| Fincan, GÖ | 1 |
| Börcek, AÖ | 1 |
| Seçen, AE | 1 |
| Ercan, S | 1 |
| Ross, HH | 1 |
| Rahman, M | 1 |
| Levkoff, LH | 1 |
| Millette, S | 1 |
| Martin-Carreras, T | 1 |
| Dunbar, EM | 1 |
| Reynolds, BA | 1 |
| Laywell, ED | 1 |
| Laymon, CM | 1 |
| Oborski, MJ | 1 |
| Lee, VK | 1 |
| Davis, DK | 1 |
| Wiener, EC | 1 |
| Lieberman, FS | 1 |
| Boada, FE | 1 |
| Mountz, JM | 1 |
| Hasabelnaby, S | 1 |
| Goudah, A | 1 |
| Agarwal, HK | 1 |
| abd Alla, MS | 1 |
| Ohno, S | 1 |
| Nishi, T | 1 |
| Kojima, Y | 1 |
| Haraoka, J | 1 |
| Ito, H | 1 |
| Mizuguchi, J | 1 |
| Black, CA | 1 |
| Ucci, JW | 1 |
| Vorpagel, JS | 1 |
| Mauck, MC | 1 |
| Fenlon, EE | 1 |
| Yoon, JT | 1 |
| Palazzo, AF | 1 |
| Xiao, D | 1 |
| Delohery, TM | 1 |
| Warburton, PE | 1 |
| Bruce, JN | 1 |
| Thompson, WJ | 1 |
| Sperl, G | 1 |
| Whitehead, C | 1 |
| Fetter, J | 1 |
| Pamukcu, R | 1 |
| Gundersen, GG | 1 |
| Weinstein, IB | 1 |
| Barbero, S | 1 |
| Bajetto, A | 1 |
| Bonavia, R | 1 |
| Porcile, C | 1 |
| Piccioli, P | 1 |
| Pirani, P | 1 |
| Ravetti, JL | 1 |
| Zona, G | 1 |
| Spaziante, R | 1 |
| Florio, T | 1 |
| Schettini, G | 1 |
| Ross, BD | 1 |
| Chenevert, TL | 1 |
| Garwood, M | 1 |
| Kim, B | 1 |
| Stegman, LD | 1 |
| Ben-Yoseph, O | 1 |
| Zwolshen, J | 1 |
| Rehemtulla, A | 1 |
| Sunkara, PS | 1 |
| Wells, JM | 2 |
| Mankoff, DA | 4 |
| Eary, JF | 3 |
| Spence, AM | 5 |
| Muzi, M | 3 |
| O'Sullivan, F | 3 |
| Vernon, CB | 1 |
| Link, JM | 4 |
| Krohn, KA | 5 |
| Morrone, FB | 1 |
| Jacques-Silva, MC | 1 |
| Horn, AP | 1 |
| Bernardi, A | 1 |
| Schwartsmann, G | 1 |
| Rodnight, R | 1 |
| Lenz, G | 1 |
| Bauréus-Koch, C | 1 |
| Nyberg, G | 1 |
| Widegren, B | 1 |
| Salford, LG | 1 |
| Persson, BR | 1 |
| Buchegger, F | 2 |
| Adamer, F | 1 |
| Schaffland, AO | 1 |
| Kosinski, M | 1 |
| Grannavel, C | 1 |
| Dupertuis, YM | 2 |
| de Tribolet, N | 2 |
| Mach, JP | 2 |
| Delaloye, AB | 1 |
| Zhang, Y | 1 |
| Zhang, YF | 1 |
| Bryant, J | 1 |
| Charles, A | 1 |
| Boado, RJ | 1 |
| Pardridge, WM | 1 |
| Al-Madhoun, AS | 1 |
| Johnsamuel, J | 1 |
| Chandra, S | 1 |
| Smith, DR | 1 |
| Guo, M | 1 |
| Roman, RJ | 1 |
| Falck, JR | 1 |
| Edwards, PA | 1 |
| Scicli, AG | 1 |
| Chen, SH | 1 |
| Gillespie, GY | 1 |
| Benveniste, EN | 1 |
| Thirumamagal, BT | 1 |
| Schellens, JH | 2 |
| Beijnen, JH | 2 |
| Altinoz, MA | 1 |
| Gedikoglu, G | 1 |
| Sav, A | 1 |
| Ozcan, E | 1 |
| Ozdilli, K | 1 |
| Bilir, A | 1 |
| Del Maestro, RF | 1 |
| Chen, W | 1 |
| Delaloye, S | 1 |
| Silverman, DH | 1 |
| Geist, C | 1 |
| Czernin, J | 1 |
| Sayre, J | 1 |
| Satyamurthy, N | 1 |
| Pope, W | 1 |
| Lai, A | 1 |
| Phelps, ME | 1 |
| Cloughesy, T | 2 |
| Oikonomou, E | 1 |
| Buchfelder, M | 1 |
| Adams, EF | 2 |
| Ogashiwa, M | 1 |
| Hoshino, T | 12 |
| Muraoka, I | 2 |
| Hervatin, S | 1 |
| Elliott, LH | 1 |
| Brooks, WH | 1 |
| Roszman, TL | 1 |
| Cronkite, EP | 1 |
| Fairchild, RG | 1 |
| Miller, ME | 1 |
| Samuels, LL | 1 |
| Straw, JA | 1 |
| Kobayashi, S | 2 |
| Berdel, WE | 2 |
| Greiner, E | 1 |
| Fink, U | 1 |
| Zänker, KS | 1 |
| Stavrou, D | 1 |
| Trappe, A | 1 |
| Fahlbusch, R | 2 |
| Reichert, A | 1 |
| Rastetter, J | 1 |
| Molnar, P | 1 |
| Groothuis, D | 1 |
| Blasberg, R | 1 |
| Zaharko, D | 1 |
| Owens, E | 1 |
| Fenstermacher, J | 1 |
| Kokunai, T | 1 |
| Tamaki, N | 1 |
| Matsumoto, S | 1 |
| Wiezsaecker, M | 1 |
| Garg, UC | 1 |
| Turndorf, H | 1 |
| Bansinath, M | 1 |
| Shewach, DS | 1 |
| Zerbe, LK | 1 |
| Hughes, TL | 1 |
| Roessler, BJ | 1 |
| Breakefield, XO | 1 |
| Davidson, BL | 1 |
| Tsai, CH | 1 |
| Hung, LM | 1 |
| Cheng, HP | 1 |
| Chen, JK | 1 |
| Toki, S | 1 |
| Yoshida, M | 1 |
| Ando, K | 1 |
| Matsuda, Y | 1 |
| Schrell, UM | 1 |
| Gauer, S | 1 |
| Kiesewetter, F | 1 |
| Bickel, A | 1 |
| Hren, J | 1 |
| Barg, J | 1 |
| Belcheva, MM | 1 |
| Levy, R | 1 |
| McHale, RJ | 1 |
| McLachlan, JA | 1 |
| Johnson, FE | 1 |
| Coscia, CJ | 1 |
| Vogel, Z | 1 |
| Ferrer, I | 1 |
| Santamaría, J | 1 |
| Alcántara, S | 1 |
| Zújar, MJ | 1 |
| Cinós, C | 1 |
| Camby, I | 1 |
| Salmon, I | 1 |
| Danguy, A | 1 |
| Pasteels, JL | 1 |
| Brotchi, J | 1 |
| Martinez, J | 1 |
| Kiss, R | 1 |
| Jeitner, TM | 1 |
| Renton, FJ | 1 |
| Chen, J | 1 |
| Willingham, T | 1 |
| Shuford, M | 1 |
| Nisen, PD | 1 |
| Tenenbaum, L | 1 |
| Teugels, E | 1 |
| Dogusan, Z | 1 |
| Avellana-Adalid, V | 1 |
| Hooghe-Peters, EL | 1 |
| Piepmeier, JM | 1 |
| Pedersen, PE | 1 |
| Yoshida, D | 1 |
| Greer, C | 1 |
| Oelmann, E | 1 |
| Kraemer, A | 1 |
| Serve, H | 1 |
| Reufi, B | 1 |
| Oberberg, D | 1 |
| Patt, S | 1 |
| Herbst, H | 1 |
| Stein, H | 1 |
| Thiel, E | 1 |
| Conti, PS | 1 |
| Hilton, J | 1 |
| Wong, DF | 1 |
| Alauddin, MM | 1 |
| Dannals, RF | 1 |
| Ravert, HT | 1 |
| Wilson, AA | 1 |
| Anderson, JH | 1 |
| Yamamoto, S | 1 |
| Wakimoto, H | 1 |
| Aoyagi, M | 1 |
| Hirakawa, K | 1 |
| Hamada, H | 1 |
| Meikle, SR | 1 |
| Matthews, JC | 1 |
| Cunningham, VJ | 1 |
| Bailey, DL | 1 |
| Livieratos, L | 1 |
| Jones, T | 1 |
| Price, P | 1 |
| Miccoli, L | 1 |
| Poirson-Bichat, F | 1 |
| Sureau, F | 1 |
| Bras Gonçalves, R | 1 |
| Bourgeois, Y | 1 |
| Dutrillaux, B | 1 |
| Poupon, MF | 1 |
| Oudard, S | 1 |
| Abaza, MS | 1 |
| Shaban, FA | 1 |
| Narayan, RK | 1 |
| Atassi, MZ | 1 |
| Berger, MS | 1 |
| Olshen, A | 1 |
| De Reuck, J | 1 |
| Santens, P | 1 |
| Goethals, P | 1 |
| Strijckmans, K | 1 |
| Lemahieu, I | 1 |
| Boon, P | 1 |
| Achten, E | 1 |
| Lemmerling, M | 1 |
| Vandekerckhove, T | 1 |
| Caemaert, J | 1 |
| Forgeur, A | 1 |
| Willems, F | 1 |
| Winand, J | 1 |
| Robberecht, P | 1 |
| Delporte, C | 1 |
| Catlin, MC | 1 |
| Guizzetti, M | 1 |
| Costa, LG | 1 |
| Robe, PA | 1 |
| Rogister, B | 1 |
| Merville, MP | 1 |
| Bours, V | 1 |
| van den Bongard, HJ | 1 |
| Mathĵt, RA | 1 |
| Boogerd, W | 1 |
| Schornagel, JH | 1 |
| Soesan, M | 1 |
| Vazquez, M | 1 |
| Pichard, C | 1 |
| Slosman, DO | 1 |
| Hernández-Angeles, A | 1 |
| Soria-Jasso, LE | 1 |
| Ortega, A | 1 |
| Arias-Montaño, JA | 1 |
| Kawanabe, Y | 1 |
| Hashimoto, N | 1 |
| Masaki, T | 1 |
| Robins, HI | 1 |
| Chang, SM | 1 |
| Prados, MD | 1 |
| Yung, WK | 2 |
| Hess, K | 1 |
| Schiff, D | 1 |
| Greenberg, H | 1 |
| Fink, K | 1 |
| Nicolas, K | 1 |
| Kuhn, JG | 1 |
| Junck, L | 1 |
| Mehta, M | 1 |
| Chacko, MS | 1 |
| Ma, X | 1 |
| Adamo, ML | 1 |
| Fukui, M | 2 |
| Yamakawa, Y | 1 |
| Yamasaki, T | 1 |
| Kitamura, K | 1 |
| Tabira, T | 1 |
| Basler, GA | 1 |
| Shapiro, WR | 5 |
| Kölmel, HW | 1 |
| Choné, BK | 1 |
| Baskin, F | 1 |
| Davis, R | 1 |
| Rosenberg, RN | 1 |
| Wilson, BC | 1 |
| Ellis, WG | 1 |
| Nomura, K | 2 |
| Knebel, K | 1 |
| Deen, DF | 1 |
| Barker, M | 4 |
| Gray, JW | 1 |
| Hasegawa, H | 1 |
| Posner, JB | 2 |
| Basler, G | 1 |
| Wilson, CB | 4 |
| Majak, M | 1 |
| Pruszczyński, M | 1 |
| Wheeler, KT | 1 |
| Shields, AF | 1 |
| Graham, MM | 1 |
| Kozawa, SM | 1 |
| Kozell, LB | 1 |
| Swenson, ER | 1 |
| Bassingthwaighte, JB | 1 |
| Slepko, NG | 1 |
| Kozlova, MV | 1 |
| Silbergeld, DL | 1 |
| Ali-Osman, F | 1 |
| Winn, HR | 1 |
| Pollack, IF | 2 |
| Randall, MS | 2 |
| Kristofik, MP | 2 |
| Kelly, RH | 2 |
| Selker, RG | 2 |
| Vertosick, FT | 2 |
| Merrill, MJ | 1 |
| Edwards, NA | 1 |
| Inoue, T | 1 |
| Iwaki, T | 1 |
| Takeshita, I | 1 |
| Franzini, A | 1 |
| Ferraresi, S | 1 |
| Giorgi, C | 1 |
| Costa, A | 1 |
| Allegranza, A | 1 |
| Broggi, G | 1 |
| Kunz, J | 1 |
| Gottschalk, J | 1 |
| Jänisch, W | 1 |
| Schulz, W | 1 |
| Vrignaud, P | 1 |
| Londos-Gagliardi, D | 1 |
| Robert, J | 1 |
| Pertuiset, B | 1 |
| Dougherty, D | 1 |
| Cromeyer, C | 1 |
| Berger, M | 1 |
| Rosenblum, ML | 1 |
| Citoler, P | 2 |
| Thomas, C | 2 |
| Sano, K | 1 |
| Nagai, M | 1 |
| Kolár, O | 1 |
| Zeman, W | 1 |
| Ciembroniewicz, J | 1 |
| Veselý, F | 1 |
| Goffinet, DR | 1 |
| Brown, JM | 1 |
| Bagshaw, MA | 1 |
| Kaplan, HS | 1 |
| Lokshina, AM | 1 |
| Pelevina, II | 1 |
| Hugosson, R | 1 |
| Källén, B | 1 |
| Nilsson, O | 1 |
| Foltz, EL | 1 |
| Tym, R | 1 |
| Aksiutina, MS | 1 |
| Lipchina, LP | 1 |
| Iablonovskaia, LIa | 1 |
| Boldrey, EB | 1 |
| Fewer, D | 1 |
| Mundinger, F | 1 |
| Ostertag, B | 1 |
| Wahlström, T | 1 |
| Saksela, E | 2 |
| Troupp, H | 1 |
| Lievens, A | 2 |
| Limbosch, S | 2 |
| Heilporn, V | 2 |
| Zampetti-Bosseler, F | 2 |
| Gibson, DA | 1 |
| Reichlin, S | 1 |
| Vernadakis, A | 1 |
| Sirtori, CR | 1 |
| Rodriguez, GA | 1 |
| Guarino, MJ | 1 |
| Azarnoff, RS | 1 |
| Boulos, BM | 1 |
| Chen, TT | 1 |
| Mealey, J | 1 |
| Steinert, G | 1 |
| Drechsler, HJ | 1 |
| Grossi-Paoletti, E | 1 |
| Paoletti, P | 1 |
| Pezzotta, S | 1 |
| Schiffer, D | 1 |
| Fabiani, A | 1 |
| Downey, R | 1 |
| Fukuma, S | 1 |
| Taketomo, S | 1 |
| Ueda, S | 1 |
| Omachi, J | 1 |
| Toyama, M | 1 |
| Kissel, P | 1 |
| Duprez, A | 1 |
| Barrucand, D | 1 |
| Holmström, T | 1 |
| Nyström, S | 1 |
| Saxén, E | 1 |
| Coutelle, R | 1 |
| Bonk, U | 1 |
| Coutelle, C | 1 |
| Felicetti, D | 1 |
| Rath, FW | 1 |
| Traub, F | 1 |
4 reviews available for thymidine and Brain Neoplasms
| Article | Year |
|---|---|
True tracers: comparing FDG with glucose and FLT with thymidine.
Topics: Animals; Brain; Brain Mapping; Brain Neoplasms; Dideoxynucleosides; Fluorodeoxyglucose F18; Glucose; | 2005 |
Are there unexploited possibilities for the therapeutic use of radioactive and stable isotopically labeled DNA precursors and extracorporeal irradiation of the blood in treatment of leukemia?
Topics: Acute Disease; Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Chemical Fractionation; DN | 1983 |
In vitro chemosensitivity testing and its clinical application in human gliomas.
Topics: Amino Acids; Antineoplastic Agents; Biological Factors; Brain Neoplasms; Colorimetry; Coloring Agent | 1989 |
[Radiation sensitization of brain neoplasms by haloid analogs of pyrimidine bases].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinoma, Ehrlich Tumor; Cricetinae; DNA, Neoplasm; Fe | 1973 |
2 trials available for thymidine and Brain Neoplasms
| Article | Year |
|---|---|
2-[C-11]thymidine imaging of malignant brain tumors.
Topics: Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carbon Dioxide; Carbon Radioisotopes; Glioblastom | 1999 |
A phase II trial of thymidine and carboplatin for recurrent malignant glioma: a North American Brain Tumor Consortium Study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Drug Admi | 2002 |
113 other studies available for thymidine and Brain Neoplasms
| Article | Year |
|---|---|
LMO4 is an essential cofactor in the Snail2-mediated epithelial-to-mesenchymal transition of neuroblastoma and neural crest cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Brain Neoplasms; Cadherins; Cell L | 2013 |
Evaluation of TK1 targeting carboranyl thymidine analogs as potential delivery agents for neutron capture therapy of brain tumors.
Topics: Animals; Boron Neutron Capture Therapy; Brain Neoplasms; Rats; Thymidine; Thymidine Kinase | 2015 |
Correlation of 4'-[methyl-(11)C]-thiothymidine uptake with Ki-67 immunohistochemistry and tumor grade in patients with newly diagnosed gliomas in comparison with (11)C-methionine uptake.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biological Transport; Brain Neoplasms; Carbon Radioisoto | 2016 |
Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma.
Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine Kinase; | 2016 |
Thymidine kinase 1 as a molecular target for boron neutron capture therapy of brain tumors.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Line, Tumor; Mice; Mi | 2008 |
Rapid inhibition of ongoing DNA synthesis in human glioma tissue by genistein.
Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Brain Neoplasms; DNA; Dose-Response Relationship, Dru | 2009 |
Establishment of a primary pleomorphic xanthoastrocytoma cell line: in vitro responsiveness to some chemotherapeutics.
Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cell Count; Cell Proliferation; Dru | 2012 |
Ethynyldeoxyuridine (EdU) suppresses in vitro population expansion and in vivo tumor progression of human glioblastoma cells.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Comet Assay; | 2011 |
Combined imaging biomarkers for therapy evaluation in glioblastoma multiforme: correlating sodium MRI and F-18 FLT PET on a voxel-wise basis.
Topics: Adult; Biomarkers; Brain Neoplasms; Female; Fluorine Radioisotopes; Glioblastoma; Humans; Image Proc | 2012 |
Synthesis, chemical and enzymatic hydrolysis, and aqueous solubility of amino acid ester prodrugs of 3-carboranyl thymidine analogs for boron neutron capture therapy of brain tumors.
Topics: Amino Acids; Animals; Boron Neutron Capture Therapy; Brain Neoplasms; Cattle; Chemistry Techniques, | 2012 |
Combined stimulation with interferon alpha and retinoic acid synergistically inhibits proliferation of the glioblastoma cell line GB12.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Brain Neoplas | 2002 |
Stereoselective and improved syntheses and anticancer testing of 3'-O-silatranylthymidines.
Topics: Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Bridged Bicyclo Compounds, Heterocyclic; C | 2002 |
CP248, a derivative of exisulind, causes growth inhibition, mitotic arrest, and abnormalities in microtubule polymerization in glioma cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; 3T3 Cells; Animals; Antine | 2002 |
Expression of the chemokine receptor CXCR4 and its ligand stromal cell-derived factor 1 in human brain tumors and their involvement in glial proliferation in vitro.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Neoplasms; Cell Division; Chemokine CXCL12; Chemokines, | 2002 |
Evaluation of (E)-2'-deoxy-2'-(fluoromethylene)cytidine on the 9L rat brain tumor model using MRI.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Su | 2003 |
Kinetic analysis of 2-[11C]thymidine PET imaging studies of malignant brain tumors: preliminary patient results.
Topics: Brain Neoplasms; Carbon Dioxide; Carbon Radioisotopes; Cell Division; DNA, Neoplasm; Humans; Kinetic | 2002 |
Kinetic analysis of 2-[11C]thymidine PET imaging studies of malignant brain tumors: compartmental model investigation and mathematical analysis.
Topics: Biological Transport, Active; Brain Neoplasms; Carbon Radioisotopes; Cell Division; DNA, Neoplasm; H | 2002 |
Extracellular nucleotides and nucleosides induce proliferation and increase nucleoside transport in human glioma cell lines.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Brain Neoplasms; Cell Division; DNA; Extra | 2003 |
Radiation sterilisation of cultured human brain tumour cells for clinical immune tumour therapy.
Topics: Brain Neoplasms; Cell Division; Cell Survival; Cesium Radioisotopes; Genetic Therapy; Glioblastoma; | 2004 |
Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts.
Topics: Animals; Brain Neoplasms; DNA; Floxuridine; Glioblastoma; Humans; Idoxuridine; Iodine Radioisotopes; | 2004 |
Intravenous RNA interference gene therapy targeting the human epidermal growth factor receptor prolongs survival in intracranial brain cancer.
Topics: Animals; Base Sequence; Blotting, Western; Brain; Brain Neoplasms; Calcium; Cell Line, Tumor; DNA; D | 2004 |
Boron-containing nucleosides as potential delivery agents for neutron capture therapy of brain tumors.
Topics: Animals; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Cell Division; Glioma; Hum | 2004 |
Human U251 glioma cell proliferation is suppressed by HET0016 [N-hydroxy-N'-(4-butyl-2-methylphenyl)formamidine], a selective inhibitor of CYP4A.
Topics: Amidines; Antineoplastic Agents; Arachidonic Acid; Blotting, Western; Brain Neoplasms; Cell Line, Tu | 2005 |
Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Astrocytes; Astrocytoma; Blotting, Western; Brain Neop | 2006 |
Preparation and biological evaluation of 10B-enriched 3-[5-{2-(2,3-dihydroxyprop-1-yl)-o-carboran-1-yl}pentan-1-yl]thymidine (N5-2OH), a new boron delivery agent for boron neutron capture therapy of brain tumors.
Topics: Animals; Binding Sites; Boron Compounds; Boron Neutron Capture Therapy; Brain Neoplasms; Calcium; Gl | 2006 |
[Management recommendations in patients with methotrexate intoxication].
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Female; Humans; Kidney; Leucovorin; Lymphoma; Lymp | 2007 |
Medroxyprogesterone acetate induces c6 glioma chemosensitization via antidepressant-like lysosomal phospholipidosis/myelinosis in vitro.
Topics: Animals; Antidepressive Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplast | 2007 |
Predicting treatment response of malignant gliomas to bevacizumab and irinotecan by imaging proliferation with [18F] fluorothymidine positron emission tomography: a pilot study.
Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chem | 2007 |
Cholecystokinin (CCK) and CCK receptor expression by human gliomas: Evidence for an autocrine/paracrine stimulatory loop.
Topics: Autocrine Communication; Brain Neoplasms; Caspase 3; Caspase Inhibitors; Cell Line, Tumor; Cell Prol | 2008 |
[Variability of radioactive thymidine labeling in the rat brain tumor model (author's transl)].
Topics: Animals; Autoradiography; Brain Neoplasms; Kinetics; Neoplasms, Experimental; Rats; Thymidine; Triti | 1980 |
Cytokinetic basis for the impaired activation of lymphocytes from patients with primary intracranial tumors.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Female; Glioblastoma; Humans; Interleukin-2; | 1984 |
Improved therapeutic index with high-dose methotrexate: comparison of thymidine-purine rescue with citrovorum factor rescue in mice.
Topics: Animals; Brain Neoplasms; Deoxycytidine; DNA Replication; Dose-Response Relationship, Drug; Hypoxant | 1984 |
Combined cytotoxic effect of low-dose 5-fluorouracil and hydroxyurea on 9L cells in vitro.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Survival; Drug Synergism; Drug Therapy, Combination; Fluor | 1983 |
Cytotoxic effects of alkyl-lysophospholipids in human brain tumor cells.
Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cell Survival; Cells, Cultured; Glioma; Histocy | 1984 |
Regional thymidine transport and incorporation in experimental brain and subcutaneous tumors.
Topics: Animals; Biological Transport; Brain; Brain Neoplasms; Carbon Radioisotopes; DNA Replication; Glioma | 1984 |
[Mechanisms of the tumor promoting effect of 12-0-tetradecanoyl phorbol 13-acetate on the ethylnitrosourea induced transplacental neurogenic carcinogenesis].
Topics: Animals; Brain Neoplasms; Carcinogens; Chromosome Aberrations; DNA, Neoplasm; Ethylnitrosourea; Fema | 1984 |
Effect of tritiated thymidine on the kinetics and viability of 9L cells in vitro.
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; Cell Survival; Colony-Forming Units Assay; Gliom | 1981 |
Effect of cocaine on macromolecular syntheses and cell proliferation in cultured glial cells.
Topics: Animals; Animals, Newborn; Brain Neoplasms; Cell Division; Cells, Cultured; Cocaine; DNA; Glioma; Gl | 1993 |
Enhanced cytotoxicity of antiviral drugs mediated by adenovirus directed transfer of the herpes simplex virus thymidine kinase gene in rat glioma cells.
Topics: Acyclovir; Adenoviruses, Human; Animals; Arabinonucleosides; Avian Sarcoma Viruses; Brain Neoplasms; | 1994 |
Increased intracellular cyclic AMP levels suppress the mitogenic responses of human astrocytoma cells to growth factors.
Topics: Astrocytoma; Blotting, Western; Brain Neoplasms; Bucladesine; Cell Division; Cyclic AMP; Glial Fibri | 1995 |
PS-990, a novel microbial metabolite, reversibly induces neurite extension in neuroblastoma cells.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acremonium; Animals; Brain Neoplasms; Calmodulin; Culture Media | 1995 |
Inhibition of proliferation of human cerebral meningioma cells by suramin: effects on cell growth, cell cycle phases, extracellular growth factors, and PDGF-BB autocrine growth loop.
Topics: Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Division; DNA; Dose-Response Relationship, Drug | 1995 |
A monoclonal anti-idiotypic antibody to opioid receptors labels desipramine-induced opioid binding sites on rat C6 glioma cells and attenuates thymidine incorporation into DNA.
Topics: Animals; Antibodies, Monoclonal; Brain Neoplasms; Cell Division; Cell Membrane; Colorimetry; Densito | 1994 |
Neuronal ectopic masses induced by prenatal irradiation in the rat.
Topics: Animals; Autoradiography; Brain Neoplasms; Choristoma; Female; Golgi Apparatus; Immunohistochemistry | 1993 |
Influence of gastrin on human astrocytic tumor cell proliferation.
Topics: Amino Acid Sequence; Astrocytoma; Autoradiography; Benzodiazepinones; Brain Neoplasms; Cell Division | 1996 |
Inhibition of the proliferation of human neural neoplastic cell lines by cysteamine.
Topics: Blood-Brain Barrier; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line; Cysteamine; DNA, Neoplas | 1996 |
Tumor suppression and inhibition of aneuploid cell accumulation in human brain tumor cells by ectopic overexpression of the cyclin-dependent kinase inhibitor p27KIP1.
Topics: Aneuploidy; Animals; Astrocytoma; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Cycle Protein | 1996 |
Plastic phenotype of human oligodendroglial tumour cells in vitro.
Topics: Antigens, Neoplasm; Autoradiography; Biomarkers, Tumor; Brain Neoplasms; Culture Media; Fibroblast G | 1996 |
Targeting microtubule-associated proteins in glioblastoma: a new strategy for selective therapy.
Topics: Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Carrier Proteins; Cell Line; Colony-For | 1996 |
Autocrine interleukin-1 receptor antagonist can support malignant growth of glioblastoma by blocking growth-inhibiting autocrine loop of interleukin-1.
Topics: Binding Sites; Brain Neoplasms; Cell Division; Glioblastoma; Humans; Interleukin 1 Receptor Antagoni | 1997 |
High performance liquid chromatography of carbon-11 labeled thymidine and its major catabolites for clinical PET studies.
Topics: Animals; Brain Neoplasms; Carbon Radioisotopes; Chromatography, High Pressure Liquid; Dogs; Glioblas | 1994 |
Modulation of motility and proliferation of glioma cells by hepatocyte growth factor.
Topics: Adolescent; Adult; Aged; Base Sequence; Brain Neoplasms; Cell Division; Cell Movement; DNA Primers; | 1997 |
Parametric image reconstruction using spectral analysis of PET projection data.
Topics: Algorithms; Astrocytoma; Biophysical Phenomena; Biophysics; Brain Neoplasms; Carbon Radioisotopes; C | 1998 |
Potentiation of lonidamine and diazepam, two agents acting on mitochondria, in human glioblastoma treatment.
Topics: Animals; Anti-Anxiety Agents; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Division; Diaz | 1998 |
In vitro inhibition of human malignant brain tumour cell line proliferation by anti-urokinase-type plasminogen activator monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; | 1998 |
[Methyl-11C]thymidine positron emission tomography in tumoral and non-tumoral cerebral lesions.
Topics: Adolescent; Adult; Aged; Astrocytoma; Blood-Brain Barrier; Brain Diseases; Brain Neoplasms; Carbon R | 1999 |
Natriuretic peptide receptors of type A in human neuroblastomas.
Topics: Apoptosis; Atrial Natriuretic Factor; Brain Neoplasms; Cell Division; Child; Child, Preschool; Enzym | 1999 |
Effect of ethanol on muscarinic receptor-induced calcium responses in astroglia.
Topics: Animals; Astrocytes; Astrocytoma; Brain Neoplasms; Calcium; Carbachol; Central Nervous System Depres | 2000 |
Growth regulation of astrocytes and C6 cells by TGFbeta1: correlation with gap junctions.
Topics: Animals; Animals, Newborn; Astrocytes; Brain Neoplasms; Cell Communication; Cell Division; Connexin | 2000 |
Successful rescue with leucovorin and thymidine in a patient with high-dose methotrexate induced acute renal failure.
Topics: Acute Kidney Injury; Antimetabolites, Antineoplastic; Brain Neoplasms; Drug Therapy, Combination; Hu | 2001 |
Fluorodeoxyuridine improves imaging of human glioblastoma xenografts with radiolabeled iododeoxyuridine.
Topics: Animals; Brain Neoplasms; Cell Cycle; DNA, Neoplasm; Drug Synergism; Floxuridine; Glioblastoma; Huma | 2001 |
Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells.
Topics: Astrocytoma; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Ac | 2001 |
Effects of extracellular Ca2+ influx on endothelin-1-induced intracellular mitogenic cascades in C6 glioma cells.
Topics: Acetamides; Animals; Brain Neoplasms; Calcium; Calcium Channel Blockers; Calcium Channels; DNA; Drug | 2002 |
Double-stranded ribonucleic acid decreases c6 rat glioma cell proliferation in part by activating protein kinase R and decreasing insulin-like growth factor I levels.
Topics: Animals; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Division; Cell Line; Coloring Agents; | 2002 |
3H-thymidine autoradiography of CSF cells in primary reticulum cell sarcoma of the brain.
Topics: Adult; Autoradiography; Brain Neoplasms; Cerebrospinal Fluid; DNA, Neoplasm; Humans; Lymphoma, Non-H | 1975 |
Comparison of 2,2'-anhydro-1-beta-D-arabinofuranosyl-5-fluorocytosine and cytosine arabinoside in the treatment of murine brain tumor.
Topics: Ancitabine; Animals; Brain Neoplasms; Cell Survival; Cytarabine; DNA, Neoplasm; Lethal Dose 50; Mice | 1976 |
Combined application of cytodiagnostic technics to the cerebrospinal fluid.
Topics: Adenocarcinoma; Adolescent; Aged; Autoradiography; Brain Neoplasms; Breast Neoplasms; Central Nervou | 1977 |
Altered thymidine kinase or thymidylate synthetase activities in 5-fluoro deoxyuridine resistant variants of mouse neuroblastoma.
Topics: Animals; Brain Neoplasms; Cell Division; Cells, Cultured; Floxuridine; Methyltransferases; Mice; Neo | 1977 |
Gemistocytic astrocytes in gliomas. An autoradiographic study.
Topics: Adolescent; Adult; Aged; Astrocytes; Astrocytoma; Autoradiography; Brain Neoplasms; Frontal Lobe; Gl | 1975 |
BCNU-induced perturbations in the cell cycle of 9L rat brain tumor cells.
Topics: Animals; Autoradiography; Brain Neoplasms; Carmustine; Cell Cycle; Cell Line; Cytological Techniques | 1978 |
Flow cytometry of isolated nuclei prepared from 9L rat brain tumor.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Nucleus; Cytological Techniques; DNA, Neoplasm; Inte | 1979 |
Effect of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride on experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line; Drug Evaluation, Preclinical; Ependymoma | 1979 |
The stathmokinetic (mitostatic) effect of vincristine and vinblastine on human gliomas.
Topics: Adult; Aged; Biopsy; Brain; Brain Neoplasms; Female; Glioma; Humans; Male; Middle Aged; Mitotic Inde | 1979 |
An autoradiographic study of the NK/Ly tumor transplanted into the brain of the mouse.
Topics: Animals; Autoradiography; Brain Neoplasms; Lymphoma, Non-Hodgkin; Male; Mice; Neoplasm Transplantati | 1978 |
Chemotherapeutic implications of early tumor cell growth in an animal brain-tumor model.
Topics: Animals; Brain Neoplasms; Cell Division; Disease Models, Animal; DNA, Neoplasm; Male; Neoplasms, Exp | 1975 |
Contribution of labeled carbon dioxide to PET imaging of carbon-11-labeled compounds.
Topics: Acetates; Animals; Brain Neoplasms; Carbon Dioxide; Carbon Radioisotopes; Dogs; Glioma; Glucose; Hum | 1992 |
[The effect of the synthetic leu-enkephalin analog dalargin on the proliferative activity of glioma C6 cells and on the intensity of their DNA synthesis].
Topics: Animals; Brain Neoplasms; Cell Division; Cell Line; DNA, Neoplasm; Drug Interactions; Enkephalin, Le | 1992 |
Induction of transformational changes in normal endothelial cells by cultured human astrocytoma cells.
Topics: Aneuploidy; Astrocytoma; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Culture Media; | 1991 |
Response of malignant glioma cell lines to activation and inhibition of protein kinase C-mediated pathways.
Topics: Animals; Brain; Brain Neoplasms; Cell Division; DNA, Neoplasm; Epidermal Growth Factor; Glioma; Huma | 1990 |
Insulin-like growth factor-I receptors in human glial tumors.
Topics: Binding, Competitive; Brain Neoplasms; Cell Membrane; Chromatography, Affinity; DNA, Neoplasm; Gliom | 1990 |
Response of malignant glioma cell lines to epidermal growth factor and platelet-derived growth factor in a serum-free medium.
Topics: Brain Neoplasms; Cell Division; Culture Media; Epidermal Growth Factor; Glioma; Humans; Iodine Radio | 1990 |
Cell kinetics of intracerebrally implanted RG-C6 tumors in rats--effects of intracarotid hyperosmolar mannitol measured by 3H-thymidine autoradiography and bromodeoxyuridine uptake.
Topics: Animals; Autoradiography; Brain Neoplasms; Bromodeoxyuridine; Carotid Artery, Internal; Cell Cycle; | 1988 |
Cell kinetic investigations in brain tumors studied by serial stereotactic biopsy.
Topics: Adolescent; Adult; Astrocytoma; Biopsy; Brain Neoplasms; Cell Division; Child; Child, Preschool; Fem | 1989 |
[Cell proliferation and glial fibrillary acidic protein in brain tumors].
Topics: Adolescent; Adult; Astrocytoma; Autoradiography; Brain Neoplasms; Cell Division; Cell Transformation | 1986 |
Cellular pharmacology of doxorubicin in sensitive and resistant rat glioblastoma cells in culture.
Topics: Animals; Brain Neoplasms; Cell Count; Cell Division; Cells, Cultured; Doxorubicin; Drug Resistance; | 1986 |
Stem cell studies of human malignant brain tumors. Part 2: Proliferation kinetics of brain-tumor cells in vitro in early-passage cultures.
Topics: Brain Neoplasms; Cell Division; Cells, Cultured; Glioma; Humans; Kinetics; Thymidine | 1985 |
[3H-thymidin-autoradiography of experimentally produced tumors of the nervous system of the rat].
Topics: Animals; Autoradiography; Brain Neoplasms; DNA, Neoplasm; Glioma; Neoplasms, Experimental; Neoplasms | 1968 |
Radiosensitization of brain tumor cells with a thymidine analogue (bromouridine).
Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Culture Techniques; DNA; Floxuridine; Fluorouracil; | 1968 |
[On the significance of eosinophilic leukocytes in neurologic diseases].
Topics: Adult; Anaphylaxis; Brain Neoplasms; Child, Preschool; Diffuse Cerebral Sclerosis of Schilder; Eosin | 1969 |
Prolonged carotid arterial radiosensitizer infusion and radiation therapy of mouse gliomas.
Topics: Animals; Brain Neoplasms; Bromine; Carotid Arteries; Catheterization; Craniotomy; Cytidine; Deoxyrib | 1972 |
Neuroglia proliferation studies in tissue culture.
Topics: Animals; Astrocytoma; Brain; Brain Neoplasms; Cell Division; Colchicine; Culture Techniques; DNA; Gl | 1968 |
Neurologic surgery.
Topics: Animals; Brain Neoplasms; Cats; Dogs; Fluorouracil; Glioblastoma; Humans; Hypothermia, Induced; Lami | 1970 |
Distribution of cell doubling times in in vivo human cerebral tumors.
Topics: Brain Neoplasms; Deoxyuridine; DNA; Glioblastoma; Humans; Infusions, Parenteral; Mitosis; Models, Th | 1969 |
[Proliferative activity of neuroglial tumors].
Topics: Adult; Animals; Astrocytoma; Autoradiography; Brain Neoplasms; Child, Preschool; Ependymoma; Female; | 1970 |
Cell kinetics of human gliomas.
Topics: Astrocytoma; Autoradiography; Brain; Brain Neoplasms; Carbon Isotopes; DNA; Glioblastoma; Glioma; Hu | 1972 |
[Clinical and experimental results of interstitial Curie-therapy combined with radiosensitizing agents in DS carcinoma of the rat and in infiltrating brain neoplasms].
Topics: Animals; Brain Neoplasms; Bromodeoxyuridine; Carcinosarcoma; Cytidine; Ependymoma; Glioblastoma; Hum | 1972 |
[Radiation effects on the embryonal and abnormal development of the central nervous system in mammals].
Topics: Animals; Bone and Bones; Brain; Brain Neoplasms; Cell Differentiation; Central Nervous System; Cereb | 1972 |
Cell-bound antiglial immunity in patients with malignant tumors of the brain.
Topics: Antigens, Neoplasm; Astrocytoma; Autoradiography; Brain Neoplasms; Cells, Cultured; Chromium Isotope | 1973 |
Morphology and X-ray sensitivity of rat glial cells after cytochalasin B treatment.
Topics: Animals; Brain Neoplasms; Cell Line; Cell Nucleus; Cytochalasin B; DNA, Neoplasm; In Vitro Technique | 1974 |
(3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following dibutyryl cyclic AMP treatment.
Topics: Animals; Astrocytoma; Brain Neoplasms; Bucladesine; Cell Line; DNA, Neoplasm; Models, Biological; Ne | 1974 |
Effect of trans-1,4-bis-2-dichlorbenzyl-aminoethyl-cyclohexane (AY-9944) on the experimental brain tumor G26A.
Topics: Animals; Anticholesteremic Agents; Benzyl Compounds; Brain Neoplasms; Cells, Cultured; Cyclohexanes; | 1972 |
Effect of corticosteroid on protein and nucleic acid synthesis in human glial tumor cells.
Topics: Brain Neoplasms; Cell Line; DNA, Neoplasm; Dose-Response Relationship, Drug; Glioma; Humans; In Vitr | 1973 |
Morphological modifications of rat glial tumor cells after x-irradiation.
Topics: Animals; Autoradiography; Brain Neoplasms; Cell Survival; Cytoplasm; DNA, Neoplasm; Dose-Response Re | 1973 |
The chemotherapy of intracerebral vs subcutaneous murine gliomas. A comparative study of the effect of VM 26.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Disease Models, Animal; DNA, Neoplasm; Ependymoma; | 1974 |
Corticosteroid hormones. Effects in an experimental brain tumor.
Topics: Animals; Brain; Brain Edema; Brain Neoplasms; Dexamethasone; DNA, Neoplasm; Ependymoma; Male; Methyl | 1974 |
[Blood brain barrier for thymidine in experimentally produced tumors of the central nervous system of the rat].
Topics: Animals; Autoradiography; Blood-Brain Barrier; Brain Neoplasms; DNA, Neoplasm; Glioma; Neoplasms, Ex | 1971 |
Tumors of the nervous system induced by ethylnitrosourea administered either intracerebrally of subcutaneously to newborn rats. Morphological and biochemical characteristics.
Topics: Animals; Brain; Brain Neoplasms; Desmosterol; DNA; DNA, Neoplasm; Ependymoma; Female; Glioma; Neuril | 1972 |
The effect of chemotherapeutic agents on the incorporation of DNA precursors by experimental brain tumors.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Bone Marrow; Brain; Brain Neoplasms; Carbon Iso | 1972 |
Kinetics of gliomas in rat and man.
Topics: Animals; Autoradiography; Brain Neoplasms; Carbon Isotopes; DNA, Neoplasm; Glioma; Humans; Kinetics; | 1972 |
[Autoradiographic studies of the growth of brain tumors using local labeling with 3H-thymidine in vivo].
Topics: Astrocytoma; Brain Neoplasms; Cerebral Ventriculography; Child, Preschool; Ganglioneuroma; Humans; I | 1969 |
[In vivo isotopic labelling of DNA in neoplastic cells of 2 human brain tumors].
Topics: Astrocytoma; Autoradiography; Brain Neoplasms; Chemical Phenomena; Chemistry, Physical; DNA; Histolo | 1967 |
Growth behaviour of human brain tumours in matrix cultures in fresh autologous serum.
Topics: Autoradiography; Blood; Brain Neoplasms; Culture Media; Fibrin Foam; Glioma; Growth; Humans; Meningi | 1970 |
[Comparative histological and electron microscopic, histochemical and biochemical studies on invasive tumor growth. IV. Behavior of certain transferases oxidoreductases and hydrolases].
Topics: Acid Phosphatase; Animals; Brain; Brain Chemistry; Brain Neoplasms; Carcinoma, Ehrlich Tumor; Glucur | 1970 |