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thymidine and Brain Inflammation

thymidine has been researched along with Brain Inflammation in 13 studies

Research Excerpts

ExcerptRelevanceReference
"Methoxymethyldeoxyuridine (MMUdR) when used in combination with either trifluorothymidine (F3TdR) or phosphonoformate (PFA) showed synergistic activity against herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) in vitro, whereas MMUdR and acycloguanosine (ACG) combination was antagonistic against herpes viruses."7.67Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses. ( Ayisi, NK; Babiuk, LA; Gupta, SV, 1985)
" In vitro data show that FEAU has activity against herpes simplex virus types 1 and 2 comparable to that of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluracil (FMAU, 2), 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodouracil (FIAU, 3), and acyclovir (ACV, 12)."3.671-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent. ( Benigni, DA; Brodfuehrer, PR; Chen, MS; Ghazzouli, I; Howell, HG; Mansuri, MM; Martin, JC, 1987)
"Methoxymethyldeoxyuridine (MMUdR) when used in combination with either trifluorothymidine (F3TdR) or phosphonoformate (PFA) showed synergistic activity against herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) in vitro, whereas MMUdR and acycloguanosine (ACG) combination was antagonistic against herpes viruses."3.67Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses. ( Ayisi, NK; Babiuk, LA; Gupta, SV, 1985)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199013 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matulic-Adamic, J1
Takahashi, K1
Chou, TC1
Gadler, H1
Price, RW1
Reddy, AR1
Kalman, TI1
Watanabe, KA1
Mansuri, MM1
Ghazzouli, I1
Chen, MS1
Howell, HG1
Brodfuehrer, PR1
Benigni, DA1
Martin, JC1
Machida, H2
Sakata, S1
Morozumi, M1
Kiyanagi, T1
Kuninaka, A2
Yoshino, H2
Ichikawa, M1
Saneyoshi, M1
Ayisi, NK1
Gupta, SV1
Babiuk, LA1
Rand, KH1
Bodor, N1
el Koussi, AA1
Raad, I1
Miyake, A1
Houck, H1
Gildersleeve, N1
Barnes, DM1
Hughes, D1
Caspary, EA2
Field, EJ1
Saunders, M1
Chambers, ME1
Knowles, M1
Gardner-Medwin, D1
Walker, P1
Perlmann, P1
Holm, G1
Johnson, RT1
Bergstrand, H1
Källén, B1

Reviews

2 reviews available for thymidine and Brain Inflammation

ArticleYear
Cytotoxic effects of lymphoid cells in vitro.
    Advances in immunology, 1969, Volume: 11

    Topics: Antibodies; Antigen-Antibody Reactions; Antigens; Autoantibodies; Autoimmune Diseases; Blood Cell Co

1969
Inflammatory response to viral infection.
    Research publications - Association for Research in Nervous and Mental Disease, 1971, Volume: 49

    Topics: Animals; Antibody Formation; Antilymphocyte Serum; Central Nervous System; Chemotaxis; Cytopathogeni

1971

Other Studies

11 other studies available for thymidine and Brain Inflammation

ArticleYear
Nucleosides. 150. Synthesis and some biological properties of 5-monofluoromethyl, 5-difluoromethyl, and 5-trifluoromethyl derivatives of 2'-deoxyuridine and 2'-deoxy-2'-fluoro-beta-D-arabinofuranosyluracil.
    Journal of medicinal chemistry, 1988, Volume: 31, Issue:8

    Topics: Animals; Antiviral Agents; Arabinofuranosyluracil; Cell Division; Chemical Phenomena; Chemistry; Deo

1988
1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:5

    Topics: Acyclovir; Animals; Arabinofuranosyluracil; Cell Line; Chemical Phenomena; Chemistry; Encephalitis;

1987
Comparison of the in vitro and in vivo anti-herpes activities of 1-beta-D-arabinofuranosylthymine and its 5'-monophosphate.
    Antiviral research, 1982, Volume: 2, Issue:4

    Topics: Animals; Antiviral Agents; Arabinonucleosides; Arabinonucleotides; Cell Line; Cell Survival; Cytopat

1982
Effect of treatment with 1-beta-D-arabinofuranosylthymine of experimental encephalitis induced by herpes simplex virus in mice.
    Antimicrobial agents and chemotherapy, 1980, Volume: 17, Issue:2

    Topics: Animals; Antiviral Agents; Arabinonucleosides; Dose-Response Relationship, Drug; Encephalitis; Femal

1980
Combination chemotherapy: interaction of 5-methoxymethyldeoxyuridine with trifluorothymidine, phosphonoformate and acycloguanosine against herpes simplex viruses.
    Antiviral research, 1985, Volume: 5, Issue:1

    Topics: Acyclovir; Animals; Antiviral Agents; Deoxyuridine; DNA, Viral; Drug Combinations; Drug Resistance,

1985
Potential treatment of herpes simplex virus encephalitis by brain-specific delivery of trifluorothymidine using a dihydropyridine in equilibrium pyridinium salt type redox delivery system.
    Journal of medical virology, 1986, Volume: 20, Issue:1

    Topics: Animals; Antiviral Agents; Blood-Brain Barrier; Brain Chemistry; Chromatography, High Pressure Liqui

1986
Brain damage by AIDS under active study.
    Science (New York, N.Y.), 1987, Mar-27, Volume: 235, Issue:4796

    Topics: Acquired Immunodeficiency Syndrome; Antigens, Differentiation, T-Lymphocyte; Antigens, Surface; Cell

1987
Lymphocyte trnsformation induced by encephalitogenic factor in multiple sclerosis and other neurological diseases.
    Lancet (London, England), 1968, Dec-07, Volume: 2, Issue:7580

    Topics: Culture Techniques; Encephalitis; Humans; Lymphocytes; Multiple Sclerosis; Nervous System Diseases;

1968
Cellular and humoral responses to measles in subacute sclerosing panencephalitis.
    Lancet (London, England), 1969, Jan-11, Volume: 1, Issue:7585

    Topics: Animals; Antibodies; Antigens; Brain; Child; Deuterium; DNA; Encephalitis; Haplorhini; Humans; In Vi

1969
Herpes simplex encephalitis.
    JAMA, 1968, Mar-04, Volume: 203, Issue:10

    Topics: Encephalitis; Herpes Simplex; Humans; Simplexvirus; Thymidine

1968
Transformation of rabbit blood leucocytes with a bovine encephalitogen--temporal pattern of reactivity.
    Acta pathologica et microbiologica Scandinavica. Section B: Microbiology and immunology, 1971, Volume: 79, Issue:4

    Topics: Animals; Antigen-Antibody Reactions; Antigens; Brain; Cattle; Culture Techniques; Encephalitis; Immu

1971
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