Page last updated: 2024-11-06

thymidine and Brain Diseases

thymidine has been researched along with Brain Diseases in 15 studies

Brain Diseases: Pathologic conditions affecting the BRAIN, which is composed of the intracranial components of the CENTRAL NERVOUS SYSTEM. This includes (but is not limited to) the CEREBRAL CORTEX; intracranial white matter; BASAL GANGLIA; THALAMUS; HYPOTHALAMUS; BRAIN STEM; and CEREBELLUM.

Research Excerpts

ExcerptRelevanceReference
"The effect of thiamine deficiency on rat brain DNA and RNA synthesis was investigated."7.65Reversible impairment of cerebral DNA synthesis in thiamine deficiency. ( Henderson, GI; Schenker, S, 1975)
"The effect of thiamine deficiency on rat brain DNA and RNA synthesis was investigated."3.65Reversible impairment of cerebral DNA synthesis in thiamine deficiency. ( Henderson, GI; Schenker, S, 1975)
"Brain lesions in patients with AIDS were nonspecific regarding metabolic profile as determined with MR spectroscopic imaging."1.31Quantitative MR spectroscopic imaging of brain lesions in patients with AIDS: correlation with [11C-methyl]thymidine PET and thallium-201 SPECT. ( Barker, PB; Bizzi, A; Constantinides, CD; Dobgan, AS; McArthur, JC; Pomper, MG; Wong, DF; Yokoi, F, 2002)
"Treatment with zidovudine and weekly infusions of gammaglobulin led to considerable clinical improvement and an almost normal computed tomogram nine weeks later."1.27AIDS encephalopathy with response to treatment. ( Bird, AG; Matthes, J; Walker, LA; Watson, JG, 1988)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199012 (80.00)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hirano, M1
Martí, R1
Spinazzola, A1
Nishino, I1
Nishigaki, Y1
De Reuck, J1
Santens, P1
Goethals, P1
Strijckmans, K1
Lemahieu, I1
Boon, P1
Achten, E1
Lemmerling, M1
Vandekerckhove, T1
Caemaert, J1
Pomper, MG1
Constantinides, CD1
Barker, PB1
Bizzi, A1
Dobgan, AS1
Yokoi, F1
McArthur, JC1
Wong, DF1
Henderson, GI1
Schenker, S1
Reinis, S1
Matthes, J1
Walker, LA1
Watson, JG1
Bird, AG1
Yarchoan, R1
Berg, G1
Brouwers, P2
Fischl, MA1
Spitzer, AR1
Wichman, A1
Grafman, J1
Thomas, RV1
Safai, B1
Brunetti, A1
Pizzo, PA1
Eddy, J1
Falloon, J1
Balis, FM1
Murphy, RF1
Moss, H1
Wolters, P1
Jarosinski, P1
Rubin, M1
Goerttler, K1
Arnold, HP1
Michalk, DV1
Narayan, O1
McFarland, HF1
Johnson, RT1
Oehmichen, M1
Grüninger, H1
Saebisch, R1
Narita, Y1
Adams, DH2
Caspary, EA1
Field, EJ1
Roessmann, U1
Friede, RL1
Ule, G1
Kolkmann, FW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase I /II Study of the Protease Inhibitor Indinavir (MK-0639) in Children With HIV Infection[NCT00001443]Phase 163 participants Interventional1995-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for thymidine and Brain Diseases

ArticleYear
The nature of the scrapie agent. A review of recent progress.
    Pathologie-biologie, 1970, Volume: 18, Issue:9

    Topics: Animals; Binding Sites; Brain; Brain Chemistry; Brain Diseases; Cell Membrane; Centrifugation; Chrom

1970

Other Studies

14 other studies available for thymidine and Brain Diseases

ArticleYear
Thymidine phosphorylase deficiency causes MNGIE: an autosomal recessive mitochondrial disorder.
    Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

    Topics: Blotting, Southern; Brain Diseases; Chromatography, High Pressure Liquid; Genes, Recessive; Genetic

2004
[Methyl-11C]thymidine positron emission tomography in tumoral and non-tumoral cerebral lesions.
    Acta neurologica Belgica, 1999, Volume: 99, Issue:2

    Topics: Adolescent; Adult; Aged; Astrocytoma; Blood-Brain Barrier; Brain Diseases; Brain Neoplasms; Carbon R

1999
Quantitative MR spectroscopic imaging of brain lesions in patients with AIDS: correlation with [11C-methyl]thymidine PET and thallium-201 SPECT.
    Academic radiology, 2002, Volume: 9, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Brain Diseases; Carbon Radioisotopes; Humans; Lymphoma, AIDS-Rel

2002
Reversible impairment of cerebral DNA synthesis in thiamine deficiency.
    The Journal of laboratory and clinical medicine, 1975, Volume: 86, Issue:1

    Topics: Adenine; Animals; Brain; Brain Diseases; Carbon Radioisotopes; DNA; Female; Hypothermia; Organ Size;

1975
Incorporation of (3H)thymidine into brain DNA after cerebellar damage.
    Pediatric research, 1975, Volume: 9, Issue:11

    Topics: Animals; Animals, Newborn; Body Weight; Brain; Brain Diseases; Cerebellar Cortex; DNA; Female; Male;

1975
AIDS encephalopathy with response to treatment.
    Archives of disease in childhood, 1988, Volume: 63, Issue:5

    Topics: Antiviral Agents; Brain Diseases; Child, Preschool; gamma-Globulins; HIV Seropositivity; Humans; Mal

1988
Response of human-immunodeficiency-virus-associated neurological disease to 3'-azido-3'-deoxythymidine.
    Lancet (London, England), 1987, Jan-17, Volume: 1, Issue:8525

    Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Diseases; Humans; Male; Middle Aged; Nervous System

1987
Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection.
    The New England journal of medicine, 1988, Oct-06, Volume: 319, Issue:14

    Topics: Acquired Immunodeficiency Syndrome; Brain; Brain Diseases; Child; Child, Preschool; Follow-Up Studie

1988
[Carcinogen-induced diaplacental effects in the rat. (Histological findings and the kinetics of DNA metabolism following the application of aflatoxin B1, methylazoxymethanol-acetate, and ethylnitrosourea)].
    Zeitschrift fur Krebsforschung, 1970, Volume: 74, Issue:4

    Topics: Acetates; Aflatoxins; Animals; Azo Compounds; Brain; Brain Diseases; Carcinogens; Chemical and Drug

1970
Effects of viral infection on nervous system development. II. Attempts to modify bluetongue-virus-induced malformations with cyclophosphamide and antithymocyte serum.
    The American journal of pathology, 1972, Volume: 68, Issue:1

    Topics: Age Factors; Animals; Animals, Newborn; Autoradiography; Bluetongue; Brain; Brain Diseases; Cyclopho

1972
[Transformation of blood monocytes into microglia and pericytes and their ability to proliferate. Experimental autoradiographical and enzyme histochemical studies with normal and damaged brain tissues of rabbits and rats].
    Acta neuropathologica, 1973, Feb-19, Volume: 23, Issue:3

    Topics: Animals; Autoradiography; Brain; Brain Diseases; Cell Division; Cytidine; Esterases; Female; Histocy

1973
The incorporation of (3H) thymidine and (14C) glucosamine into a DNA-polysaccharide complex in normal and scrapie-affected mouse brain.
    Archiv fur die gesamte Virusforschung, 1970, Volume: 30, Issue:2

    Topics: Animals; Brain; Brain Diseases; Carbon Isotopes; Cell Membrane; Centrifugation, Density Gradient; Ce

1970
Entry of labeled monocytic cells into the central nervous system.
    Acta neuropathologica, 1968, Jun-07, Volume: 10, Issue:4

    Topics: Animals; Autoradiography; Bone Marrow Cells; Brain; Brain Diseases; Cell Aggregation; Culture Media;

1968
[Experimental studies on Wernicke's encephalopathy].
    Acta neuropathologica, 1968, Nov-01, Volume: 11, Issue:4

    Topics: Acute Disease; Animals; Autoradiography; Blood-Brain Barrier; Brain; Brain Diseases; Columbidae; Dem

1968