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thymidine and Bone Loss, Osteoclastic

thymidine has been researched along with Bone Loss, Osteoclastic in 36 studies

Research Excerpts

ExcerptRelevanceReference
" NET at picomolar concentrations in vitro stimulated the proliferation of human TE85 osteosarcoma cells as assessed by the increase in [3H]thymidine incorporation into DNA and in cell number and also stimulated the release of osteocalcin in both the presence and absence of 10 nM 1,25-(OH)2D3."7.69Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption. ( Baylink, DJ; Demarest, KT; Lau, KH; Linkhart, TA; Wang, SP, 1994)
" NET at picomolar concentrations in vitro stimulated the proliferation of human TE85 osteosarcoma cells as assessed by the increase in [3H]thymidine incorporation into DNA and in cell number and also stimulated the release of osteocalcin in both the presence and absence of 10 nM 1,25-(OH)2D3."3.69Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption. ( Baylink, DJ; Demarest, KT; Lau, KH; Linkhart, TA; Wang, SP, 1994)
"Treatment with haloperidol did not affect bone density."1.37The atypical anti-psychotic clozapine decreases bone mass in rats in vivo. ( Callon, K; Cheng, A; Cornish, J; Costa, JL; Gamble, G; Grey, A; Lin, JM; Shepherd, PR; Smith, G; Vickers, MH; Watson, M, 2011)
"Bone resorption was observed after 6 (myeloid blasts and monocyte-derived osteoclasts) and 8 (early blast-derived osteoclasts) days."1.35Myeloid blasts are the mouse bone marrow cells prone to differentiate into osteoclasts. ( de Vries, TJ; Everts, V; Hooibrink, B; Leenen, PJ; Schoenmaker, T, 2009)
"Thus cAMP inhibited bone resorption and stimulated new bone formation in tissue culture."1.34Effect of cyclic 3', 5' adenosin-monophosphate on osteogenesis embryonic bone cultivated in tissue culture: an autoradiographic study. ( Leibur, E; Lepp, E, 2007)
"Prostaglandin E2 (PGE2) can stimulate bone resorption and formation through receptors which activate adenylyl cyclase."1.32Effects of selective prostaglandin EP2 and EP4 receptor agonists on bone resorption and formation in fetal rat organ cultures. ( Raisz, LG; Woodiel, FN, 2003)
"As both production of these enzymes and bone resorption appear to be mediated by cytokines, we investigated the effects of two cytokines, IL-1 alpha and EGF, on the release of collagenase, gelatinase A (MMP-2), gelatinase B (MMP-9), TIMP-1 and calcium by rabbit calvariae."1.30EGF and IL-1 alpha modulate the release of collagenase, gelatinase and TIMP-1 as well as the release of calcium by rabbit calvarial bone explants. ( Beertsen, W; Everts, V; Hoeben, K; Jansen, I; van der Zee, E, 1998)
"In this model, enhanced bone resorption was associated with the selective growth promotion of metastatic W256 cells in bone, suggesting the existence of a bone-derived factor which is mitogenic to W256 cells."1.28Stimulation of bone resorption results in a selective increase in the growth rate of spontaneously metastatic Walker 256 cancer cells in bone. ( Kostenuik, PJ; Orr, FW; Singh, G; Suyama, KL, 1992)
" hLIF also stimulated incorporation of [3H] thymidine into calvaria, but the dose-response relationship was distinct from that for bone resorption, and this effect was not blocked by indomethacin."1.28Leukemia inhibitory factor: a novel bone-active cytokine. ( Cornish, J; Gearing, DP; Hilton, DJ; Lowe, C; Martin, TJ; Reid, LR; Skinner, SJ; Willson, TA, 1990)
"The CsA inhibition of bone resorption could be partially surmounted by higher concentrations of PTH and 1,25(OH)2D3."1.27Cyclosporine A inhibits calcemic hormone-induced bone resorption in vitro. ( Green, OC; Stern, PH; Stewart, PJ, 1986)
"This soluble Jactor produced bone resorption in organ cultures of fetal rat bones as measured by increased release of calcium-45, and also increased the number of active osteoclasts."1.25Bone resorbing activity in supernatant fluid from cultured human peripheral blood leukocytes. ( Horton, JE; Mergenhagen, SE; Oppenheim, JJ; Raisz, LG; Simmons, HA, 1972)

Research

Studies (36)

TimeframeStudies, this research(%)All Research%
pre-199021 (58.33)18.7374
1990's11 (30.56)18.2507
2000's3 (8.33)29.6817
2010's1 (2.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
de Vries, TJ1
Schoenmaker, T1
Hooibrink, B1
Leenen, PJ1
Everts, V2
Costa, JL1
Smith, G1
Watson, M1
Lin, JM1
Callon, K1
Gamble, G1
Cheng, A1
Vickers, MH1
Shepherd, PR1
Cornish, J3
Grey, A1
Raisz, LG9
Woodiel, FN1
Leibur, E1
Lepp, E1
Saklatvala, J1
Pilsworth, LM1
Sarsfield, SJ1
Gavrilovic, J1
Heath, JK1
Kanatani, M1
Sugimoto, T1
Kaji, H1
Kano, J1
Chihara, K1
Lau, KH1
Wang, SP1
Linkhart, TA1
Demarest, KT1
Baylink, DJ2
Colucci, S1
Grano, M1
Mori, G1
Scotlandi, K1
Mastrogiacomo, M1
Mori, C1
Zallone, AZ1
Callon, KE1
Coy, DH1
Jiang, NY1
Xiao, L1
Cooper, GJ1
Reid, IR1
van der Zee, E1
Jansen, I1
Hoeben, K1
Beertsen, W1
Kim, CH1
Cheng, SL1
Kim, GS1
Dietrich, JW1
Mundy, GR2
Chen, P1
Trummel, C1
Horton, J1
Baker, JJ1
Oppenheim, JJ3
Trummel, CL1
Kostenuik, PJ1
Singh, G1
Suyama, KL1
Orr, FW1
Gaffar, A1
Alander, CB1
Marusić, A1
Reid, LR1
Lowe, C1
Skinner, SJ1
Hilton, DJ1
Willson, TA1
Gearing, DP1
Martin, TJ1
Moore, NC1
Chipman, JK1
Shen, V1
Kohler, G1
Huang, J1
Huang, SS1
Peck, WA1
Nemeth, E1
McCulloch, CA1
Melcher, AH1
Lorenzo, JA2
Quinton, J1
Sousa, S2
Turner, RT1
Farley, J1
Vandersteenhoven, JJ1
Epstein, S1
Bell, NH1
Stewart, PJ1
Green, OC1
Stern, PH2
Perry, HM1
Krieger, NS1
Stathopoulos, VM1
Burger, EH1
Boonekamp, PM1
Nijweide, PJ1
Rodionova, NV1
Brighton, CT1
Ray, RD1
Soble, LW1
Kuettner, KE1
Line, SE1
Polson, AM1
Zander, HA1
Horton, JE2
Mergenhagen, SE2
Holtrop, ME1
Simmons, HA2
Corwin, JA1
Morehead, JR1
Baumrind, S1

Other Studies

36 other studies available for thymidine and Bone Loss, Osteoclastic

ArticleYear
Myeloid blasts are the mouse bone marrow cells prone to differentiate into osteoclasts.
    Journal of leukocyte biology, 2009, Volume: 85, Issue:6

    Topics: Animals; Bone Resorption; Cell Count; Cell Differentiation; Colony-Forming Units Assay; Flow Cytomet

2009
The atypical anti-psychotic clozapine decreases bone mass in rats in vivo.
    Schizophrenia research, 2011, Volume: 126, Issue:1-3

    Topics: Absorptiometry, Photon; Analysis of Variance; Animals; Antipsychotic Agents; Bone and Bones; Bone De

2011
Effects of selective prostaglandin EP2 and EP4 receptor agonists on bone resorption and formation in fetal rat organ cultures.
    Prostaglandins & other lipid mediators, 2003, Volume: 71, Issue:3-4

    Topics: Animals; Bone Resorption; Calcium; Calcium Radioisotopes; Collagen; Dinoprostone; DNA; Hydrocortison

2003
Effect of cyclic 3', 5' adenosin-monophosphate on osteogenesis embryonic bone cultivated in tissue culture: an autoradiographic study.
    Stomatologija, 2007, Volume: 9, Issue:4

    Topics: Alveolar Process; Animals; Autoradiography; Bone Matrix; Bone Resorption; Calcification, Physiologic

2007
Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein.
    The Biochemical journal, 1984, Dec-01, Volume: 224, Issue:2

    Topics: Animals; Bone Resorption; Cartilage, Articular; Cattle; Cell Division; Cells, Cultured; Dinoprostone

1984
Effects of 22-oxacalcitriol on bone metabolism in vitro: comparison with calcitriol--effects of 22-oxacalcitriol on osteoclast-like cell formation and bone-resorbing activity.
    European journal of endocrinology, 1995, Volume: 133, Issue:5

    Topics: Alkaline Phosphatase; Animals; Anticarcinogenic Agents; Bone and Bones; Bone Resorption; Calcitriol;

1995
Picomolar norethindrone in vitro stimulates the cell proliferation and activity of a human osteosarcoma cell line and increases bone collagen synthesis without an effect on bone resorption.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1994, Volume: 9, Issue:5

    Topics: Animals; Bone and Bones; Bone Development; Bone Resorption; Calcitriol; Cell Differentiation; Cell D

1994
Retinoic acid induces cell proliferation and modulates gelatinases activity in human osteoclast-like cell lines.
    Biochemical and biophysical research communications, 1996, Oct-03, Volume: 227, Issue:1

    Topics: Bone Resorption; Cell Division; Fluorescent Antibody Technique; Gelatinases; Humans; Osteoclasts; Th

1996
Adrenomedullin is a potent stimulator of osteoblastic activity in vitro and in vivo.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Adrenomedullin; Amyloid; Animals; Animals, Newborn; Bone and Bones; Bone Resorption; Cell Division;

1997
EGF and IL-1 alpha modulate the release of collagenase, gelatinase and TIMP-1 as well as the release of calcium by rabbit calvarial bone explants.
    Journal of periodontal research, 1998, Volume: 33, Issue:1

    Topics: Analysis of Variance; Animals; Bone Resorption; Calcium; Collagenases; Culture Techniques; Enzyme-Li

1998
Effects of dexamethasone on proliferation, activity, and cytokine secretion of normal human bone marrow stromal cells: possible mechanisms of glucocorticoid-induced bone loss.
    The Journal of endocrinology, 1999, Volume: 162, Issue:3

    Topics: Alkaline Phosphatase; Bone Marrow Cells; Bone Resorption; Cell Division; Cells, Cultured; Collagen;

1999
Inhibition of bone resorption in tissue culture by membrane-stabilizing drugs.
    Endocrinology, 1979, Volume: 104, Issue:6

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; DNA; Fetus; Kinetics; Lidocaine; Parathyroid Horm

1979
Production of osteoclast-activating factor by normal human peripheral blood rosetting and nonrosetting lymphocytes.
    European journal of immunology, 1976, Volume: 6, Issue:10

    Topics: Bone Resorption; DNA; Humans; Immunologic Techniques; Lectins; Lymphocyte Activation; Lymphocytes; L

1976
Release of osteoclast activating factor by normal human peripheral blood leukocytes.
    The Journal of laboratory and clinical medicine, 1975, Volume: 85, Issue:6

    Topics: Antigen-Antibody Reactions; Biological Assay; Bone Resorption; Cells, Cultured; Humans; Immune Adher

1975
Stimulation of bone resorption results in a selective increase in the growth rate of spontaneously metastatic Walker 256 cancer cells in bone.
    Clinical & experimental metastasis, 1992, Volume: 10, Issue:6

    Topics: Animals; Body Burden; Bone Neoplasms; Bone Resorption; Calcium; Carcinoma 256, Walker; Cell Division

1992
Effects of potassium peroxydiphosphate on bone resorption.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1991, Volume: 6, Issue:10

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Cricetinae; Culture Media; Culture Techniques; Di

1991
Cortisol modulates the actions of interleukin-1 alpha on bone formation, resorption, and prostaglandin production in cultured mouse parietal bones.
    Endocrinology, 1991, Volume: 129, Issue:5

    Topics: Animals; Bone Resorption; Collagen; Dose-Response Relationship, Drug; Hydrocortisone; Indomethacin;

1991
Leukemia inhibitory factor: a novel bone-active cytokine.
    Endocrinology, 1990, Volume: 126, Issue:3

    Topics: Animals; Biological Factors; Bone and Bones; Bone Resorption; Calcium; Cytokines; Dose-Response Rela

1990
Effects of intraperitoneal administration of hexasodium N,N,N',N'-ethylenediaminetetramethylenephosphonate on rat bone metabolism.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1990, Volume: 14, Issue:3

    Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Bone and Bones; Bone Resorption; DNA; Male; Organop

1990
An acidic fibroblast growth factor stimulates DNA synthesis, inhibits collagen and alkaline phosphatase synthesis and induces resorption in bone.
    Bone and mineral, 1989, Volume: 7, Issue:3

    Topics: Alkaline Phosphatase; Animals; Bone and Bones; Bone Resorption; Cell Division; Collagen; Dinoproston

1989
Coordinated regulation of endothelial and fibroblast cell proliferation and matrix synthesis in periodontal ligament adjacent to appositional and resorptive bone surfaces.
    The Anatomical record, 1989, Volume: 223, Issue:4

    Topics: Animals; Bone Resorption; Cell Division; Endothelium; Extracellular Matrix; Fibroblasts; Male; Mice;

1989
Effects of DNA and prostaglandin synthesis inhibitors on the stimulation of bone resorption by epidermal growth factor in fetal rat long-bone cultures.
    The Journal of clinical investigation, 1986, Volume: 77, Issue:6

    Topics: Animals; Aphidicolin; Bone Resorption; Diterpenes; DNA Replication; Epidermal Growth Factor; Female;

1986
Phorbol esters stimulate bone resorption in fetal rat long-bone cultures by mechanisms independent of prostaglandin synthesis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1988, Volume: 3, Issue:1

    Topics: Animals; Aphidicolin; Bone and Bones; Bone Resorption; Calcium; Diterpenes; DNA Replication; Epiderm

1988
Demonstration of reduced mitogenic and osteoinductive activities in demineralized allogeneic bone matrix from vitamin D-deficient rats.
    The Journal of clinical investigation, 1988, Volume: 82, Issue:1

    Topics: Animals; Bone Matrix; Bone Resorption; Calcium-Binding Proteins; Fetal Blood; Minerals; Mitogens; Os

1988
Cyclosporine A inhibits calcemic hormone-induced bone resorption in vitro.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1986, Volume: 1, Issue:3

    Topics: Animals; Bone and Bones; Bone Resorption; Calcitriol; Culture Techniques; Cyclosporins; Dinoprostone

1986
Parathyroid hormone-lymphocyte interactions modulate bone resorption.
    Endocrinology, 1986, Volume: 119, Issue:5

    Topics: Bone Resorption; Cell Adhesion; Culture Media; Humans; Indomethacin; Lymphocytes; Molecular Weight;

1986
Does amrinone inhibition of stimulated bone resorption involve Na+-Ca++ exchange?
    Circulation, 1986, Volume: 73, Issue:3 Pt 2

    Topics: Aminopyridines; Amrinone; Animals; Bone Resorption; Calcium; Cardiotonic Agents; Cycloheximide; Dact

1986
Osteoblast and osteoclast precursors in primary cultures of calvarial bone cells.
    The Anatomical record, 1986, Volume: 214, Issue:1

    Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Cell Separation; Cells, Cultured; Chick Embryo; F

1986
[Dynamics and ultrastructural characteristics of osteoclast formation].
    Tsitologiia, 1985, Volume: 27, Issue:9

    Topics: Animals; Autoradiography; Bone Resorption; Cell Fusion; Cell Nucleus; DNA; Microscopy, Electron; Ost

1985
In vitro epiphyseal-plate growth in various oxygen tensions.
    The Journal of bone and joint surgery. American volume, 1969, Volume: 51, Issue:7

    Topics: Animals; Autoradiography; Bone Development; Bone Resorption; Cartilage; Culture Techniques; Epiphyse

1969
Relationship between periodontal injury, selective cell repopulation and ankylosis.
    Journal of periodontology, 1974, Volume: 45, Issue:10

    Topics: Animals; Ankylosis; Bone Marrow; Bone Marrow Cells; Bone Resorption; Connective Tissue; Connective T

1974
Macrophage-lymphocyte synergy in the production of osteoclast activating factor.
    Journal of immunology (Baltimore, Md. : 1950), 1974, Volume: 113, Issue:4

    Topics: Amino Acids; Bone Resorption; DNA; Humans; Kinetics; Lectins; Leukocytes; Lymphocyte Activation; Lym

1974
Inhibition of bone resorption by colchicine in organ culture.
    Endocrinology, 1973, Volume: 92, Issue:2

    Topics: Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Calcium Isotopes; Colchicine; Fetus;

1973
Bone resorbing activity in supernatant fluid from cultured human peripheral blood leukocytes.
    Science (New York, N.Y.), 1972, Sep-01, Volume: 177, Issue:4051

    Topics: Animals; Antigens; Bone and Bones; Bone Resorption; Calcium Isotopes; Cell-Free System; Dental Plaqu

1972
The origin of osteoclasts in estrogen-stimulated bone resorption of the pubic symphysis of the mouse.
    The Anatomical record, 1971, Volume: 171, Issue:4

    Topics: Animals; Autoradiography; Bone Resorption; Estradiol; Female; Mice; Mice, Inbred Strains; Osteoblast

1971
A reconsideration of the propriety of the "pressure-tension" hypothesis.
    American journal of orthodontics, 1969, Volume: 55, Issue:1

    Topics: Alveolar Process; Animals; Bone Resorption; Orthodontics, Corrective; Periodontium; Pressure; Prolin

1969