Page last updated: 2024-11-06

thymidine and Blast Phase

thymidine has been researched along with Blast Phase in 10 studies

Research Excerpts

ExcerptRelevanceReference
"We cultured chronic myelogenous leukemia cells from the peripheral blood of several patients in blast crisis with three inhibitors of lipoxygenases: ETYA, and the more selective A63162 (Abbott) or SC41661A (Searle)."1.29Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase. ( Anderson, KM; Harris, JE; Jajeh, A; Levin, J; Seed, T, 1993)
" Control blasts exposed to increasing ara-C concentrations gave very similar dose-response curves; in striking contrast, blast cells cultured in hydrocortisone, then pulsed with ara-C did not lose colony-forming ability even though the same population was sensitive to 3HTdR."1.28Hydrocortisone in culture protects the blast cells in acute myeloblastic leukemia from the lethal effects of cytosine arabinoside. ( McCulloch, EA; Minden, MD; Minkin, S; Wang, C; Yang, GS, 1991)
"Neoplastic cells of childhood acute lymphoblastic leukemia (ALL) with natural killer (NK) cell properties were studied for the expression of p75 interleukin-2 receptors (IL-2R) and the receptor functions."1.28Functional p75 interleukin-2 receptor expression on the fresh blast cells in childhood acute lymphoblastic leukemia with natural killer cell properties. ( Ichikawa, M; Kawai, H; Kinoshita, A; Komiyama, A; Miyasaka, M; Nakazawa, S; Tsudo, M, 1991)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19901 (10.00)18.7374
1990's8 (80.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gambacorti-Passerini, C1
Zucchetti, M1
Russo, D1
Frapolli, R1
Verga, M1
Bungaro, S1
Tornaghi, L1
Rossi, F1
Pioltelli, P1
Pogliani, E1
Alberti, D1
Corneo, G1
D'Incalci, M1
Galimberti, S1
Bianchi, F1
Bernardini, N1
Mattii, L1
Dolfi, A1
Lupetti, M1
Petrini, M1
Anderson, KM1
Levin, J1
Jajeh, A1
Seed, T1
Harris, JE1
Usuki, K1
Iki, S1
Endo, M1
Kitazume, K1
Ito, K1
Watanabe, M1
Urabe, A1
Szczylik, C1
Skórski, T1
Malaguarnera, L1
Hetman, J1
Chen, ST1
Calabretta, B1
Carter, A1
Silvian-Draxler, I1
Tatarsky, I1
Yang, GS1
Wang, C1
Minkin, S1
Minden, MD1
McCulloch, EA1
Ichikawa, M1
Kawai, H1
Komiyama, A1
Tsudo, M1
Miyasaka, M1
Kinoshita, A1
Nakazawa, S1
Panella, TJ1
Huang, AT1
Pébusque, MJ1
Lafage, M1
Lopez, M1
Mannoni, P1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label Randomized Clinical Trial to Compare the Toxicities and Efficacy of Pharmacokinetically-guided and BSA Fixed Dosing Strategy of Docetaxel and Paclitaxel in Chinese Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma, and Breast Cancer Patie[NCT01891123]300 participants (Anticipated)Interventional2013-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for thymidine and Blast Phase

ArticleYear
Alpha1 acid glycoprotein binds to imatinib (STI571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:2

    Topics: Animals; Antineoplastic Agents; Area Under Curve; Benzamides; Blast Crisis; Cell Division; Female; H

2003

Other Studies

9 other studies available for thymidine and Blast Phase

ArticleYear
Scanning electron microscopy of multidrug resistant cells in haematological and mammary malignancies.
    Cellular and molecular biology (Noisy-le-Grand, France), 1993, Volume: 39, Issue:5

    Topics: Acute Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Breas

1993
Induction of apoptosis in blood cells from a patient with acute myelogenous leukemia by SC41661A, a selective inhibitor of 5-lipoxygenase.
    Prostaglandins, leukotrienes, and essential fatty acids, 1993, Volume: 48, Issue:4

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetamides; Amides; Apoptosis; Base Sequence; Blast Crisis; Blood C

1993
Granulocyte colony-stimulating factor in acute myeloid leukemia.
    Stem cells (Dayton, Ohio), 1995, Volume: 13, Issue:6

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Blast Crisis; Cell Division; Female; Granulocyte Colo

1995
Inhibition of in vitro proliferation of chronic myelogenous leukemia progenitor cells by c-myb antisense oligodeoxynucleotides.
    Folia histochemica et cytobiologica, 1996, Volume: 34, Issue:3-4

    Topics: Antigens, CD34; beta 2-Microglobulin; Blast Crisis; Cell Division; DNA Primers; Down-Regulation; Hem

1996
Effect of interleukin-1, tumor necrosis factor-alpha, and interferon-alpha on the blast cells of acute myeloblastic leukemia.
    American journal of hematology, 1992, Volume: 40, Issue:4

    Topics: Adolescent; Adult; Aged; Blast Crisis; Bone Marrow; Cell Division; DNA; Dose-Response Relationship,

1992
Hydrocortisone in culture protects the blast cells in acute myeloblastic leukemia from the lethal effects of cytosine arabinoside.
    Journal of cellular physiology, 1991, Volume: 148, Issue:1

    Topics: Blast Crisis; Cell Survival; Cytarabine; DNA; Dose-Response Relationship, Drug; Doxorubicin; Humans;

1991
Functional p75 interleukin-2 receptor expression on the fresh blast cells in childhood acute lymphoblastic leukemia with natural killer cell properties.
    American journal of hematology, 1991, Volume: 36, Issue:4

    Topics: Adolescent; Antibodies, Monoclonal; Antigens, CD; Blast Crisis; Cell Division; Histocytochemistry; H

1991
Effect of thimerosal in leukemia, in leukemic cell lines, and on normal hematopoiesis.
    Cancer research, 1990, Jul-15, Volume: 50, Issue:14

    Topics: Antilymphocyte Serum; Blast Crisis; Cell Differentiation; Cell Line; DNA Replication; Ethylmercury C

1990
Preferential response of acute myeloid leukemias with translocation involving chromosome 17 to human recombinant granulocyte colony-stimulating factor.
    Blood, 1988, Volume: 72, Issue:1

    Topics: Animals; Blast Crisis; Bromodeoxyuridine; Cell Cycle; Cell Division; Cell Line; Cell-Free System; Ch

1988