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thymidine and Basedow Disease

thymidine has been researched along with Basedow Disease in 27 studies

Research Excerpts

ExcerptRelevanceReference
"IgG associated with Graves' disease bind to the TSH receptor and alter thyroid growth and function, mainly through the stimulation of adenylyl cyclase."1.30Cyclooxygenase-dependent thyroid cell proliferation induced by immunoglobulins from patients with Graves' disease. ( Corda, D; De Filippis, V; Di Cerbo, A; Di Paola, R; Menzaghi, C, 1997)
"[3H]-thymidine uptake was suppressed to 56."1.29Effect of monensin on DNA synthesis in cultured human thyroid cells. ( Itoh, M; Okugawa, T, 1993)
"[3H]Thymidine incorporation was also significantly increased (p < 0."1.29Analysis of fibroblast-stimulating activity in IgG from patients with Graves' dermopathy. ( Davies, R; Metcalfe, RA; Weetman, AP, 1993)
"[3H]-thymidine uptake was more suppressed by IgG from patients with a smaller-sized goiter than by those with a larger-sized one."1.28Suppression of thyroid cell growth by serum IgG in Graves' disease. ( Itoh, M; Okugawa, T; Shimomura, N, 1992)
"This paper addresses the question: in Graves' disease is there a thyroid-growth stimulating IgG (TGI) separate from thyroid-stimulating antibody (TSAb)? Using the functioning rat thyroid line (FRTL5) cells for TGI (incorporation of [3H]-thymidine into DNA) and TSAb (increase in cAMP concentration) assays, we tested IgG from 30 Graves' patients."1.27Evidence supporting the identity in Graves' disease of thyroid-stimulating antibody and thyroid growth-promoting immunoglobulin G as assayed in FRTL5 cells. ( Jin, S; McKenzie, JM; Zakarija, M, 1988)
"[3H]thymidine incorporation was significantly inhibited in the presence of sera from patients with Graves' disease and chronic thyroiditis (P less than 0."1.27Antibody-dependent cell-mediated growth inhibition of rat thyroid cells, FRTL-5, in patients with autoimmune thyroid diseases. ( Arai, K; Iida, Y; Kasagi, K; Konishi, J; Misaki, T; Tokuda, Y, 1988)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199016 (59.26)18.7374
1990's11 (40.74)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valente, WA1
Vitti, P1
Rotella, CM1
Vaughan, MM1
Aloj, SM1
Grollman, EF1
Ambesi-Impiombato, FS1
Kohn, LD1
Balázs, C2
Stenszky, V1
Kozma, L1
Farid, NR1
Chiovato, L1
Hammond, LJ1
Hanafusa, T1
Pujol-Borrell, R1
Doniach, D1
Bottazzo, GF1
Quaratino, S1
Thorpe, CJ1
Travers, PJ1
Londei, M1
Okugawa, T3
Itoh, M3
Murata, Y1
Seo, H1
Paschke, R2
Eck, T1
Herfurth, J1
Usadel, KH2
Di Cerbo, A2
Di Paola, R2
Bonati, M1
Zingrillo, M1
De Filippis, V2
Corda, D2
Metcalfe, RA1
Davies, R1
Weetman, AP1
Menzaghi, C1
McKenzie, JM3
Zakarija, M2
D'Amour, P1
Joasoo, A1
Bordan, L1
Kovacs, L1
Szerze, P1
Sztojka, I1
Leovey, A1
Shimomura, N1
Gafny, M1
Ben-David, C1
Sirkis, N1
Gordon, A1
Gross, J1
Smeds, S1
Jörtsö, E1
Tegler, L1
Teuber, J1
Enger, I1
Schmeidl, R1
Schwedes, U1
Fang, WY1
Ye, WX1
Taniguchi, S1
Yoshida, A1
Mashiba, H1
Kawabe, Y1
Eguchi, K1
Shimomura, C1
Mine, M1
Otsubo, T1
Ueki, Y1
Tezuka, H1
Nakao, H1
Kawakami, A1
Migita, K1
Tao, TW1
Leu, SL1
Kriss, JP1
Miyamoto, M1
Sugawa, H1
Kuma, K1
Mori, T1
Imura, H1
Jin, S1
Iida, Y1
Kasagi, K1
Tokuda, Y1
Arai, K1
Misaki, T1
Konishi, J1
Van Herle, AJ1
Chopra, IJ1
Folb, PI1
Bank, H1
DeGroot, LJ1
Jaksina, S1

Other Studies

27 other studies available for thymidine and Basedow Disease

ArticleYear
Antibodies that promote thyroid growth. A distinct population of thyroid-stimulating autoantibodies.
    The New England journal of medicine, 1983, Oct-27, Volume: 309, Issue:17

    Topics: Adult; Aged; Animals; Antibodies; Autoantibodies; Autoimmune Diseases; Biological Assay; Cell Line;

1983
Specific suppressor T cell function in a patient with Graves' disease and her healthy identical twin.
    Clinical endocrinology, 1984, Volume: 20, Issue:6

    Topics: Adult; Antigens, Surface; Cell Division; Concanavalin A; Diseases in Twins; Female; Graves Disease;

1984
Detection of thyroid growth immunoglobulins (TGI) by [3H]-thymidine incorporation in cultured rat thyroid follicles.
    Clinical endocrinology, 1983, Volume: 19, Issue:5

    Topics: Adult; Animals; Biological Assay; Culture Techniques; Female; Goiter; Goiter, Endemic; Graves Diseas

1983
Similar antigenic surfaces, rather than sequence homology, dictate T-cell epitope molecular mimicry.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Oct-24, Volume: 92, Issue:22

    Topics: Amino Acid Sequence; Cell Division; Clone Cells; DNA; Epitopes; Graves Disease; HLA-D Antigens; Huma

1995
Effect of aphidicolin on DNA synthesis in cultured human thyroid cells.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 1995, Volume: 103, Issue:2

    Topics: Aphidicolin; Cell Cycle; Cells, Cultured; DNA; Enzyme Inhibitors; Flow Cytometry; Graves Disease; Hu

1995
Stimulation of proliferation and inhibition of function of xenotransplanted human thyroid tissue by epidermal growth factor.
    Journal of endocrinological investigation, 1995, Volume: 18, Issue:5

    Topics: Animals; Cell Division; Epidermal Growth Factor; Epithelial Cells; Epithelium; Graves Disease; Human

1995
Subgroups of Graves' patients identified on the basis of the biochemical activities of their immunoglobulins.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:9

    Topics: Adult; Arachidonic Acid; Cyclic AMP; Female; Graves Disease; Humans; Immunoglobulin G; Male; Middle

1995
Effect of monensin on DNA synthesis in cultured human thyroid cells.
    Endocrine journal, 1993, Volume: 40, Issue:1

    Topics: Cell Cycle; Cells, Cultured; DNA; Endocytosis; Epidermal Growth Factor; Flow Cytometry; Golgi Appara

1993
Analysis of fibroblast-stimulating activity in IgG from patients with Graves' dermopathy.
    Thyroid : official journal of the American Thyroid Association, 1993,Fall, Volume: 3, Issue:3

    Topics: Cell Line; Cells, Cultured; DNA; Fibroblasts; Glucosamine; Glycosaminoglycans; Graves Disease; Human

1993
Cyclooxygenase-dependent thyroid cell proliferation induced by immunoglobulins from patients with Graves' disease.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:2

    Topics: Animals; Cell Division; Cell Line; Cyclooxygenase Inhibitors; Graves Disease; Humans; Immunoglobulin

1997
The long-acting thyroid stimulatory: is it of importance in Graves' disease.
    The New Zealand medical journal, 1975, Jan-08, Volume: 81, Issue:531

    Topics: Animals; Cyclic AMP; Female; Graves Disease; Humans; Immunoglobulin G; Long-Acting Thyroid Stimulato

1975
Immunoblasts in Graves' disease.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:8

    Topics: Adolescent; Adult; Autoradiography; Female; Graves Disease; Humans; Lymphocytes; Male; Middle Aged;

1977
Suppression of thyroid cell growth by serum IgG in Graves' disease.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1992, Volume: 24, Issue:7

    Topics: Chromatography, DEAE-Cellulose; Epidermal Growth Factor; Gene Expression; Genes, fos; Graves Disease

1992
The appearance in thyroidectomized mice of immunoglobulins that bind TSH and stimulate FRTL-5 thyrocytes.
    Acta endocrinologica, 1992, Volume: 127, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Cells, Cultured; DNA; Female; Graves Disease; Hybridomas; Immunoglo

1992
Thyroid epithelial cell proliferation in xenotransplanted human toxic nodular goitre is increased by Graves' IgG.
    Acta endocrinologica, 1991, Volume: 125, Issue:4

    Topics: Animals; Cell Division; Epithelium; Goiter, Nodular; Graves Disease; Immunoglobulin G; Iodine Radioi

1991
Evidence for a role of anti-idiotypic antibodies in the induction of remission in Graves' disease.
    Journal of autoimmunity, 1990, Volume: 3, Issue:4

    Topics: Animals; Antibodies, Anti-Idiotypic; Autoantibodies; Binding, Competitive; Biological Assay; Cell Nu

1990
Studies on suppressor T lymphocyte function in Graves' disease by 3H-thymidine interpolation.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1987, Volume: 7, Issue:1

    Topics: Adolescent; Adult; Antithyroid Agents; Graves Disease; Humans; Middle Aged; T-Lymphocytes, Regulator

1987
Direct effect of methimazole on rat thyroidal cell growth induced by thyrotropin and insulin-like growth factor I.
    Endocrinology, 1989, Volume: 124, Issue:5

    Topics: Animals; Biomechanical Phenomena; Bucladesine; Cell Division; Clone Cells; Cyclic AMP; Dose-Response

1989
Interleukin-1 production and action in thyroid tissue.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 68, Issue:6

    Topics: Biological Availability; Cell Cycle; Cells, Cultured; Culture Media; Dinoprostone; Graves Disease; H

1989
Biological activity of autoantibodies associated with Graves' dermopathy.
    The Journal of clinical endocrinology and metabolism, 1989, Volume: 69, Issue:1

    Topics: Animals; Autoantibodies; Cell Cycle; Cell Line; DNA; Female; Fibroblasts; Glycosaminoglycans; Graves

1989
Analysis of epidermal growth factor (EGF) receptor and effect of EGF on the growth of cultured Graves' and non-neoplastic human thyroid cells.
    Journal of endocrinological investigation, 1989, Volume: 12, Issue:2

    Topics: Cell Division; Cells, Cultured; Epidermal Growth Factor; ErbB Receptors; Graves Disease; Humans; Thy

1989
Evidence supporting the identity in Graves' disease of thyroid-stimulating antibody and thyroid growth-promoting immunoglobulin G as assayed in FRTL5 cells.
    The Journal of clinical investigation, 1988, Volume: 81, Issue:3

    Topics: Animals; Autoantibodies; Binding Sites, Antibody; Cell Line; Cyclic AMP; DNA; Graves Disease; Growth

1988
Antibody-dependent cell-mediated growth inhibition of rat thyroid cells, FRTL-5, in patients with autoimmune thyroid diseases.
    Acta endocrinologica, 1988, Volume: 118, Issue:4

    Topics: Adolescent; Adult; Aged; Antibodies; Cell Line; DNA; Female; Graves Disease; Growth Inhibitors; Huma

1988
Thymic hyperplasia in Graves' disease.
    The Journal of clinical endocrinology and metabolism, 1971, Volume: 32, Issue:2

    Topics: Adult; Antithyroid Agents; Autoradiography; Culture Techniques; Female; Graves Disease; Humans; Long

1971
Activated lymphocytes in the peripheral blood in acute hyperthyroidism (Graves' disease).
    Israel journal of medical sciences, 1974, Volume: 10, Issue:7

    Topics: Adult; DNA; Female; Graves Disease; Humans; Immunity, Cellular; Leukocyte Count; Lymphocyte Activati

1974
Instances of metabolic stimulation by antibody.
    Bulletin der Schweizerischen Akademie der Medizinischen Wissenschaften, 1969, Volume: 24, Issue:5

    Topics: Adipose Tissue; Animals; Antibodies; Autoantibodies; DNA; Graves Disease; Guinea Pigs; Kidney; Long-

1969
Observations on the role of circulating lymphocytes in thyroid auto-immunity.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:2

    Topics: Autoimmune Diseases; Carbon Isotopes; Cell Differentiation; Culture Techniques; DNA; Graves Disease;

1969