thymidine has been researched along with Astrocytoma in 44 studies
Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In human astrocytoma U373 MG cells that express histamine H1 receptors (180 +/- 6 fmol/mg protein) but not H2 or H3 receptors, histamine stimulated mitogenesis as assessed by [3H]-thymidine incorporation (173 +/- 2% of basal; EC50, 2." | 7.71 | Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells. ( Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE, 2001) |
| "Combination of autoradiography and ultracytochemical acridine orange method in rat astrocytoma C6 cells is described." | 7.67 | Electron microscopic localization of acridine orange binding to DNA within rat astrocytoma C6 cells. ( Hara, H; Hiroi, M; Moriki, T; Yamane, T, 1984) |
| "Gefitinib was shown to inhibit proliferation in all five JPA cell-cultures tested, with IC-50's between 1." | 5.33 | Gefitinib is effective against juvenile pilocytic astrocytoma in vitro. ( Donson, AM; Foreman, NK; Gore, L; Heideman, R; Straessle, J; Wells, D, 2006) |
| " Carbachol activated NF-kappaB in human 1321N1 astrocytoma cells, as evidenced by translocation of the p65 subunit of NF-kappaB to the nucleus, phosphorylation and degradation of IkappaBalpha in the cytosol, and increase NF-kappaB binding to DNA." | 3.72 | Nuclear factor kappaB activation by muscarinic receptors in astroglial cells: effect of ethanol. ( Bordi, F; Costa, LG; Dieguez-Acuña, FJ; Guizzetti, M; Madia, F; Vitalone, A; Woods, JS, 2003) |
| " In this study, we report on the ability of carbachol to stimulate the phosphorylation of Akt/PKB, an important target of phosphatidylinositol 3 kinase (PI3 kinase) in 1321N1 human astrocytoma cells." | 3.71 | Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells. ( Costa, LG; Guizzetti, M, 2001) |
| "In human astrocytoma U373 MG cells that express histamine H1 receptors (180 +/- 6 fmol/mg protein) but not H2 or H3 receptors, histamine stimulated mitogenesis as assessed by [3H]-thymidine incorporation (173 +/- 2% of basal; EC50, 2." | 3.71 | Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells. ( Arias-Montaño, JA; Hernández-Angeles, A; Ortega, A; Soria-Jasso, LE, 2001) |
| "Combination of autoradiography and ultracytochemical acridine orange method in rat astrocytoma C6 cells is described." | 3.67 | Electron microscopic localization of acridine orange binding to DNA within rat astrocytoma C6 cells. ( Hara, H; Hiroi, M; Moriki, T; Yamane, T, 1984) |
| " The potential proliferative activity of these different neoplasms, evaluated as in vitro 3H-thymidine labeling index (LI), has been determined in 46 mature astrocytomas, 19 anaplasic astrocytomas, 25 glioblastomas, 5 cystic craniopharyngiomas, 6 metastatic tumors, 4 primary C." | 3.67 | Cell kinetic investigations in brain tumors studied by serial stereotactic biopsy. ( Allegranza, A; Broggi, G; Costa, A; Ferraresi, S; Franzini, A; Giorgi, C, 1989) |
| "The effects of several benzodiazepines (diazepam, clonazepam, Ro 15-1788 and Ro 5-4864) on cell proliferation of 2 human gliomas were estimated in vitro by means of [3H]-thymidine uptake assay." | 3.67 | Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro. ( Kunert-Radek, J; Pawlikowski, M; Radek, A; Stepien, H, 1988) |
| "Tritiated thymidine (3-H-T) was administered intravenously to seven patients with cerebral gliomas." | 3.65 | Gemistocytic astrocytes in gliomas. An autoradiographic study. ( Ellis, WG; Hoshino, T; Wilson, BC, 1975) |
| " Essential fatty acids also restored the rate of 3H-thymidine uptake by N-18 neuroblastoma cells grown in a serum-deprived medium." | 3.65 | Effect of essential fatty acids on proliferation of two neural tumor lines. ( Menkes, JH; Yavin, E; Yavin, Z, 1975) |
| "Malignant brain tumors pose diagnostic and therapeutic problems." | 2.69 | 2-[C-11]thymidine imaging of malignant brain tumors. ( Berger, MS; Eary, JF; Krohn, KA; Link, JM; Mankoff, DA; O'Sullivan, F; Olshen, A; Spence, AM, 1999) |
| "Interestingly, OSM did not suppress astroglioma cell invasion." | 1.33 | Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases. ( Benveniste, EN; Chen, SH; Gillespie, GY, 2006) |
| "Gefitinib was shown to inhibit proliferation in all five JPA cell-cultures tested, with IC-50's between 1." | 1.33 | Gefitinib is effective against juvenile pilocytic astrocytoma in vitro. ( Donson, AM; Foreman, NK; Gore, L; Heideman, R; Straessle, J; Wells, D, 2006) |
| "Patients with malignant brain tumors have a variety of immunologic abnormalities, including the impaired responsiveness of peripheral blood lymphocytes (PBL) to mitogens and alloantigens." | 1.27 | Cytokinetic basis for the impaired activation of lymphocytes from patients with primary intracranial tumors. ( Brooks, WH; Elliott, LH; Roszman, TL, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (45.45) | 18.7374 |
| 1990's | 13 (29.55) | 18.2507 |
| 2000's | 7 (15.91) | 29.6817 |
| 2010's | 4 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Toll, L | 1 |
| Jimenez, L | 1 |
| Waleh, N | 1 |
| Jozwiak, K | 1 |
| Woo, AY | 1 |
| Xiao, RP | 1 |
| Bernier, M | 1 |
| Wainer, IW | 1 |
| Sick, E | 1 |
| Boukhari, A | 1 |
| Deramaudt, T | 1 |
| Rondé, P | 1 |
| Bucher, B | 1 |
| André, P | 1 |
| Gies, JP | 1 |
| Takeda, K | 1 |
| Bagriacik, EU | 1 |
| Baykaner, MK | 1 |
| Yaman, M | 1 |
| Sivrikaya, G | 1 |
| Durdağ, E | 1 |
| Emmez, H | 1 |
| Fincan, GÖ | 1 |
| Börcek, AÖ | 1 |
| Seçen, AE | 1 |
| Ercan, S | 1 |
| Neschadim, A | 1 |
| Wang, JC | 1 |
| Lavie, A | 1 |
| Medin, JA | 1 |
| Guizzetti, M | 3 |
| Bordi, F | 1 |
| Dieguez-Acuña, FJ | 1 |
| Vitalone, A | 1 |
| Madia, F | 1 |
| Woods, JS | 1 |
| Costa, LG | 3 |
| Nagai, S | 1 |
| Kurimoto, M | 1 |
| Washiyama, K | 1 |
| Hirashima, Y | 1 |
| Kumanishi, T | 1 |
| Endo, S | 1 |
| Chen, SH | 1 |
| Gillespie, GY | 1 |
| Benveniste, EN | 1 |
| Foreman, NK | 1 |
| Gore, L | 1 |
| Wells, D | 1 |
| Straessle, J | 1 |
| Heideman, R | 1 |
| Donson, AM | 1 |
| Elliott, LH | 1 |
| Brooks, WH | 1 |
| Roszman, TL | 1 |
| Hara, H | 1 |
| Moriki, T | 1 |
| Hiroi, M | 1 |
| Yamane, T | 1 |
| Berdel, WE | 1 |
| Greiner, E | 1 |
| Fink, U | 1 |
| Zänker, KS | 1 |
| Stavrou, D | 1 |
| Trappe, A | 1 |
| Fahlbusch, R | 1 |
| Reichert, A | 1 |
| Rastetter, J | 1 |
| Tsai, CH | 1 |
| Hung, LM | 1 |
| Cheng, HP | 1 |
| Chen, JK | 1 |
| Camby, I | 1 |
| Salmon, I | 1 |
| Danguy, A | 1 |
| Pasteels, JL | 1 |
| Brotchi, J | 1 |
| Martinez, J | 1 |
| Kiss, R | 1 |
| Chen, J | 2 |
| Willingham, T | 1 |
| Shuford, M | 1 |
| Nisen, PD | 2 |
| Luo, J | 1 |
| Miller, MW | 1 |
| Meikle, SR | 1 |
| Matthews, JC | 1 |
| Cunningham, VJ | 1 |
| Bailey, DL | 1 |
| Livieratos, L | 1 |
| Jones, T | 1 |
| Price, P | 1 |
| Abaza, MS | 1 |
| Shaban, FA | 1 |
| Narayan, RK | 1 |
| Atassi, MZ | 1 |
| Eary, JF | 1 |
| Mankoff, DA | 1 |
| Spence, AM | 1 |
| Berger, MS | 1 |
| Olshen, A | 1 |
| Link, JM | 1 |
| O'Sullivan, F | 1 |
| Krohn, KA | 1 |
| Hong, FD | 1 |
| Donovan, S | 1 |
| Schneider, N | 1 |
| De Reuck, J | 1 |
| Santens, P | 1 |
| Goethals, P | 1 |
| Strijckmans, K | 1 |
| Lemahieu, I | 1 |
| Boon, P | 1 |
| Achten, E | 1 |
| Lemmerling, M | 1 |
| Vandekerckhove, T | 1 |
| Caemaert, J | 1 |
| Arias-Montaño, JA | 2 |
| Berger, VA | 1 |
| Soria-Jasso, LE | 2 |
| Young, JM | 1 |
| Catlin, MC | 1 |
| Hernández-Angeles, A | 1 |
| Ortega, A | 1 |
| Hoshino, T | 3 |
| Wilson, BC | 1 |
| Ellis, WG | 1 |
| Yavin, E | 1 |
| Yavin, Z | 1 |
| Menkes, JH | 1 |
| Couraud, PO | 1 |
| Durieu-Trautmann, O | 1 |
| Nguyen, DL | 1 |
| Marin, P | 1 |
| Glibert, F | 1 |
| Strosberg, AD | 1 |
| Silbergeld, DL | 1 |
| Ali-Osman, F | 1 |
| Winn, HR | 1 |
| Duh, CY | 1 |
| Kinghorn, AD | 1 |
| Pezzuto, JM | 1 |
| Franzini, A | 1 |
| Ferraresi, S | 1 |
| Giorgi, C | 1 |
| Costa, A | 1 |
| Allegranza, A | 1 |
| Broggi, G | 1 |
| Kunz, J | 1 |
| Gottschalk, J | 1 |
| Jänisch, W | 1 |
| Schulz, W | 1 |
| Pawlikowski, M | 1 |
| Kunert-Radek, J | 1 |
| Radek, A | 1 |
| Stepien, H | 1 |
| Rutka, JT | 1 |
| De Armond, SJ | 1 |
| Giblin, J | 1 |
| McCulloch, JR | 1 |
| Wilson, CB | 2 |
| Rosenblum, ML | 1 |
| Sano, K | 1 |
| Nagai, M | 1 |
| Hugosson, R | 1 |
| Källén, B | 1 |
| Nilsson, O | 1 |
| Aksiutina, MS | 1 |
| Lipchina, LP | 1 |
| Iablonovskaia, LIa | 1 |
| Barker, M | 1 |
| Boldrey, EB | 1 |
| Fewer, D | 1 |
| Wahlström, T | 1 |
| Saksela, E | 1 |
| Troupp, H | 1 |
| Lim, R | 1 |
| Mitsunobu, K | 1 |
| Gibson, DA | 1 |
| Reichlin, S | 1 |
| Vernadakis, A | 1 |
| Fukuma, S | 1 |
| Taketomo, S | 1 |
| Ueda, S | 1 |
| Omachi, J | 1 |
| Toyama, M | 1 |
| Kissel, P | 1 |
| Duprez, A | 1 |
| Barrucand, D | 1 |
| Kucheria, K | 2 |
1 trial available for thymidine and Astrocytoma
| Article | Year |
|---|---|
2-[C-11]thymidine imaging of malignant brain tumors.
Topics: Astrocytoma; Blood-Brain Barrier; Brain Neoplasms; Carbon Dioxide; Carbon Radioisotopes; Glioblastom | 1999 |
43 other studies available for thymidine and Astrocytoma
| Article | Year |
|---|---|
{Beta}2-adrenergic receptor agonists inhibit the proliferation of 1321N1 astrocytoma cells.
Topics: Adrenergic beta-2 Receptor Agonists; Astrocytoma; Cell Line, Tumor; Cell Proliferation; Cyclic AMP; | 2011 |
Activation of CD47 receptors causes proliferation of human astrocytoma but not normal astrocytes via an Akt-dependent pathway.
Topics: Antibodies; Apoptosis; Astrocytes; Astrocytoma; Autophagy; Calcium; CD47 Antigen; Cell Proliferation | 2011 |
Establishment of a primary pleomorphic xanthoastrocytoma cell line: in vitro responsiveness to some chemotherapeutics.
Topics: Adolescent; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cell Count; Cell Proliferation; Dru | 2012 |
Bystander killing of malignant cells via the delivery of engineered thymidine-active deoxycytidine kinase for suicide gene therapy of cancer.
Topics: Astrocytoma; Cell Line, Tumor; Deoxycytidine Kinase; Gene Transfer Techniques; Genes, Transgenic, Su | 2012 |
Nuclear factor kappaB activation by muscarinic receptors in astroglial cells: effect of ethanol.
Topics: Astrocytes; Astrocytoma; Atropine; Blotting, Western; Carbachol; Cell Line; Cellular Structures; Cen | 2003 |
Inhibition of cellular proliferation and induction of apoptosis by curcumin in human malignant astrocytoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Astrocytoma; Cell Proliferation; Curcumin; Electrophoretic Mobilit | 2005 |
Divergent effects of oncostatin M on astroglioma cells: influence on cell proliferation, invasion, and expression of matrix metalloproteinases.
Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Astrocytes; Astrocytoma; Blotting, Western; Brain Neop | 2006 |
Gefitinib is effective against juvenile pilocytic astrocytoma in vitro.
Topics: Astrocytoma; Cell Proliferation; Central Nervous System Neoplasms; Dose-Response Relationship, Drug; | 2006 |
Cytokinetic basis for the impaired activation of lymphocytes from patients with primary intracranial tumors.
Topics: Adolescent; Adult; Aged; Astrocytoma; Brain Neoplasms; Female; Glioblastoma; Humans; Interleukin-2; | 1984 |
Electron microscopic localization of acridine orange binding to DNA within rat astrocytoma C6 cells.
Topics: Acridine Orange; Animals; Astrocytoma; Autoradiography; Cell Line; Chromatin; Deoxyribonucleases; DN | 1984 |
Cytotoxic effects of alkyl-lysophospholipids in human brain tumor cells.
Topics: Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Cell Survival; Cells, Cultured; Glioma; Histocy | 1984 |
Increased intracellular cyclic AMP levels suppress the mitogenic responses of human astrocytoma cells to growth factors.
Topics: Astrocytoma; Blotting, Western; Brain Neoplasms; Bucladesine; Cell Division; Cyclic AMP; Glial Fibri | 1995 |
Influence of gastrin on human astrocytic tumor cell proliferation.
Topics: Amino Acid Sequence; Astrocytoma; Autoradiography; Benzodiazepinones; Brain Neoplasms; Cell Division | 1996 |
Tumor suppression and inhibition of aneuploid cell accumulation in human brain tumor cells by ectopic overexpression of the cyclin-dependent kinase inhibitor p27KIP1.
Topics: Aneuploidy; Animals; Astrocytoma; Blotting, Western; Brain Neoplasms; Cell Cycle; Cell Cycle Protein | 1996 |
Ethanol inhibits basic fibroblast growth factor-mediated proliferation of C6 astrocytoma cells.
Topics: Analysis of Variance; Animals; Astrocytoma; Biomarkers; Cell Division; Cell Line; DNA, Neoplasm; Eth | 1996 |
Parametric image reconstruction using spectral analysis of PET projection data.
Topics: Algorithms; Astrocytoma; Biophysical Phenomena; Biophysics; Brain Neoplasms; Carbon Radioisotopes; C | 1998 |
In vitro inhibition of human malignant brain tumour cell line proliferation by anti-urokinase-type plasminogen activator monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antigen-Antibody Reactions; Astrocytoma; Biomarkers, Tumor; Brain Neoplasms; | 1998 |
Taxol, vincristine or nocodazole induces lethality in G1-checkpoint-defective human astrocytoma U373MG cells by triggering hyperploid progression.
Topics: Astrocytoma; Cell Cycle; Cell Cycle Proteins; Cell Death; Cell Division; Cyclin-Dependent Kinase Inh | 1999 |
[Methyl-11C]thymidine positron emission tomography in tumoral and non-tumoral cerebral lesions.
Topics: Adolescent; Adult; Aged; Astrocytoma; Blood-Brain Barrier; Brain Diseases; Brain Neoplasms; Carbon R | 1999 |
Characterisation of alpha1B-adrenoceptors linked to inositol phosphate formation and calcium mobilisation in human astrocytoma U373 MG cells.
Topics: Adrenergic alpha-Antagonists; Astrocytoma; Calcium; Cell Membrane; Clonidine; Dihydropyridines; Diox | 1999 |
Effect of ethanol on muscarinic receptor-induced calcium responses in astroglia.
Topics: Animals; Astrocytes; Astrocytoma; Brain Neoplasms; Calcium; Carbachol; Central Nervous System Depres | 2000 |
Activation of phosphatidylinositol 3 kinase by muscarinic receptors in astrocytoma cells.
Topics: Androstadienes; Astrocytoma; Carbachol; Cholinergic Agonists; Chromones; Enzyme Inhibitors; Humans; | 2001 |
Histamine H1 receptor activation stimulates mitogenesis in human astrocytoma U373 MG cells.
Topics: Astrocytoma; Brain Neoplasms; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Enzyme Ac | 2001 |
Gemistocytic astrocytes in gliomas. An autoradiographic study.
Topics: Adolescent; Adult; Aged; Astrocytes; Astrocytoma; Autoradiography; Brain Neoplasms; Frontal Lobe; Gl | 1975 |
Effect of essential fatty acids on proliferation of two neural tumor lines.
Topics: Animals; Astrocytoma; Cell Division; Cell Line; Linoleic Acids; Linolenic Acids; Neoplasms, Experime | 1975 |
Functional endothelin-1 receptors in rat astrocytoma C6.
Topics: Animals; Aorta; Astrocytoma; Cell Membrane; Colforsin; Cyclic AMP; DNA, Neoplasm; Endothelins; Inosi | 1991 |
Induction of transformational changes in normal endothelial cells by cultured human astrocytoma cells.
Topics: Aneuploidy; Astrocytoma; Brain Neoplasms; Cell Line; Cell Transformation, Neoplastic; Culture Media; | 1991 |
Cell-cycle specific cytotoxicity mediated by stizophyllin (2 alpha,3 beta,12 beta-trihydroxypregna-4,7,16-trien-20-one), a novel electrophilic pregnane isolated from Stizophyllum riparium.
Topics: Animals; Astrocytoma; Cell Cycle; Cell Survival; CHO Cells; Cricetinae; DNA; DNA Replication; Kineti | 1991 |
Cell kinetic investigations in brain tumors studied by serial stereotactic biopsy.
Topics: Adolescent; Adult; Astrocytoma; Biopsy; Brain Neoplasms; Cell Division; Child; Child, Preschool; Fem | 1989 |
[Cell proliferation and glial fibrillary acidic protein in brain tumors].
Topics: Adolescent; Adult; Astrocytoma; Autoradiography; Brain Neoplasms; Cell Division; Cell Transformation | 1986 |
Inhibition of cell proliferation of human gliomas by benzodiazepines in vitro.
Topics: Astrocytoma; Benzodiazepines; Benzodiazepinones; Cell Division; Clonazepam; Diazepam; Female; Flumaz | 1988 |
Effect of retinoids on the proliferation, morphology and expression of glial fibrillary acidic protein of an anaplastic astrocytoma cell line.
Topics: Astrocytoma; Cell Adhesion; Cell Division; Glial Fibrillary Acidic Protein; Humans; Male; Middle Age | 1988 |
Radiosensitization of brain tumor cells with a thymidine analogue (bromouridine).
Topics: Astrocytoma; Brain Neoplasms; Bromodeoxyuridine; Culture Techniques; DNA; Floxuridine; Fluorouracil; | 1968 |
Neuroglia proliferation studies in tissue culture.
Topics: Animals; Astrocytoma; Brain; Brain Neoplasms; Cell Division; Colchicine; Culture Techniques; DNA; Gl | 1968 |
[Proliferative activity of neuroglial tumors].
Topics: Adult; Animals; Astrocytoma; Autoradiography; Brain Neoplasms; Child, Preschool; Ependymoma; Female; | 1970 |
Cell kinetics of human gliomas.
Topics: Astrocytoma; Autoradiography; Brain; Brain Neoplasms; Carbon Isotopes; DNA; Glioblastoma; Glioma; Hu | 1972 |
Cell-bound antiglial immunity in patients with malignant tumors of the brain.
Topics: Antigens, Neoplasm; Astrocytoma; Autoradiography; Brain Neoplasms; Cells, Cultured; Chromium Isotope | 1973 |
Effect of dibutyryl cyclic AMP on nucleic acid and protein synthesis in neuronal and glial tumor cells.
Topics: Animals; Astrocytoma; Butyrates; Cell Count; Cell Differentiation; Cell Division; Cell Line; Clone C | 1972 |
(3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following dibutyryl cyclic AMP treatment.
Topics: Animals; Astrocytoma; Brain Neoplasms; Bucladesine; Cell Line; DNA, Neoplasm; Models, Biological; Ne | 1974 |
[Autoradiographic studies of the growth of brain tumors using local labeling with 3H-thymidine in vivo].
Topics: Astrocytoma; Brain Neoplasms; Cerebral Ventriculography; Child, Preschool; Ganglioneuroma; Humans; I | 1969 |
[In vivo isotopic labelling of DNA in neoplastic cells of 2 human brain tumors].
Topics: Astrocytoma; Autoradiography; Brain Neoplasms; Chemical Phenomena; Chemistry, Physical; DNA; Histolo | 1967 |
Autoradiographic analysis of the cell cycle of five solid human tumours in vitro.
Topics: Astrocytoma; Autoradiography; Cell Line; Child, Preschool; Culture Techniques; Female; Humans; Infan | 1970 |
Chromosomal DNA replication pattern in human tumour cells in vitro.
Topics: Astrocytoma; Cell Line; Chromosomes; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X | 1970 |