thymidine has been researched along with Arthritis, Rheumatoid in 86 studies
Arthritis, Rheumatoid: A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was undertaken to examine the effects of magnosalin, a compound isolated from 'Shin-i' (Flos magnoliae) on proliferation of synovial cells isolated from MRL/1pr and collagen-induced arthritis (CIA) mice, and rheumatoid arthritis (RA) patients." | 7.70 | Inhibitory effects of anti-rheumatic drugs containing magnosalin, a compound from 'Shin-i' (Flos magnoliae), on the proliferation of synovial cells in rheumatoid arthritis models. ( Kimura, I; Kimura, M; Kobayashi, H; Kobayashi, S; Matsuno, H, 1998) |
| "To assess the role of T lymphocyte sensitization in the etiology of side effects of gold therapy in patients with rheumatoid arthritis (RA)." | 7.68 | Activation of gold-reactive T lymphocytes in rheumatoid arthritis patients treated with gold. ( Gambling, L; Kingsley, GH; Panayi, GS; Verwilghen, J, 1992) |
| "Tritiated-thymidine incorporating cells in synovial tissue samples from ten patients with definite or classic rheumatoid arthritis (RA) were studied by combining two techniques." | 7.67 | Phenotypic characterization of 3H-thymidine incorporating cells in rheumatoid arthritis synovial membrane. ( Bergroth, V; Konttinen, YT; Nordström, D; Nykänen, P; Raunio, P, 1986) |
| "Sulfasalazine is now an established 2nd line agent in the treatment of rheumatoid arthritis (RA) but its mode of action is unknown." | 7.67 | Sulfasalazine treatment and lymphocyte function in patients with rheumatoid arthritis. ( Bacon, PA; Farr, M; Salmon, M; Symmons, DP, 1988) |
| "Cultures of washed erythrocytes from rheumatoid arthritis patients and normal subjects were found to incorporated 14C-thymidine, suggesting the presence of an L-form." | 7.66 | Incorporation of 14C-thymidine by cultures of erythrocytes from rheumatoid arthritis patients and normal subjects, suggesting the presence of an L-form. ( Bartlett, R; Farr, M; Pease, PE, 1981) |
| "The sertraline-treated rats showed a significant reduction in clinical arthritis compared to controls, at all doses given, accompanied by a significant increase in interleukin 10 and a decrease in tumor necrosis factor-α levels and cycloxygenase-2 production, without lymphotoxicity." | 5.38 | Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis. ( Baharav, E; Bar, M; Gil-Ad, I; Karp, L; Taler, M; Weinberger, A; Weizman, A, 2012) |
| "3H-thymidine degradation was prevented by adding 5-nitrouracil to the incubation medium at a concentration of 0." | 5.27 | The significance of 3H-thymidine degradation in cell culture experiments with special reference to rheumatoid arthritis. ( Kankaanpää, PU; Nykänen, PJ; Raunio, PV, 1988) |
| "This study was undertaken to examine the effects of magnosalin, a compound isolated from 'Shin-i' (Flos magnoliae) on proliferation of synovial cells isolated from MRL/1pr and collagen-induced arthritis (CIA) mice, and rheumatoid arthritis (RA) patients." | 3.70 | Inhibitory effects of anti-rheumatic drugs containing magnosalin, a compound from 'Shin-i' (Flos magnoliae), on the proliferation of synovial cells in rheumatoid arthritis models. ( Kimura, I; Kimura, M; Kobayashi, H; Kobayashi, S; Matsuno, H, 1998) |
| "To assess the role of T lymphocyte sensitization in the etiology of side effects of gold therapy in patients with rheumatoid arthritis (RA)." | 3.68 | Activation of gold-reactive T lymphocytes in rheumatoid arthritis patients treated with gold. ( Gambling, L; Kingsley, GH; Panayi, GS; Verwilghen, J, 1992) |
| "The phenomenon of increased spontaneous incorporation of 3H-thymidine (3H-TdR) into peripheral blood mononuclear cells in rheumatoid arthritis (RA) has been investigated." | 3.67 | Characteristics of spontaneously proliferating mononuclear cells in rheumatoid arthritis. ( Dickson, R; Froebel, K; Jasani, MK; Lewis, D; Sturrock, RD, 1984) |
| "Tritiated-thymidine incorporating cells in synovial tissue samples from ten patients with definite or classic rheumatoid arthritis (RA) were studied by combining two techniques." | 3.67 | Phenotypic characterization of 3H-thymidine incorporating cells in rheumatoid arthritis synovial membrane. ( Bergroth, V; Konttinen, YT; Nordström, D; Nykänen, P; Raunio, P, 1986) |
| "Sulfasalazine is now an established 2nd line agent in the treatment of rheumatoid arthritis (RA) but its mode of action is unknown." | 3.67 | Sulfasalazine treatment and lymphocyte function in patients with rheumatoid arthritis. ( Bacon, PA; Farr, M; Salmon, M; Symmons, DP, 1988) |
| "Infectious Epstein-Barr (EB) virus obtained from the B95-8 marmoset cell line was used to infect mononuclear cells from healthy controls and patients with rheumatoid arthritis (RA) and ankylosing spondylitis (AS), and outgrowth of B cells into lymphoblastoid cell lines was assessed by visual microscopy and uptake of tritiated thymidine over a 28 day period." | 3.67 | Deficient control of in vitro Epstein-Barr virus infection in patients with ankylosing spondylitis. ( Panayi, GS; Robinson, S, 1986) |
| "The responses of synovial lymphocytes to 12 microbiological antigens, including 8 viral antigens, were studied with the 3H-thymidine uptake procedure in 15 patients with rheumatoid arthritis (RA) and 4 patients with Reiter's syndrome." | 3.66 | Observations on the responses of synovial lymphocytes to viral antigens in rheumatoid arthritis and Reiter's syndrome. ( da Roza, DM; Ford, DK, 1983) |
| "The activity of blood mononuclear cells (BMC) and synovial fluid mononuclear cells (SMC) from patients with rheumatoid arthritis (RA) and traumatic synovitis (TS) was assessed by means of [14C]thymidine incorporation and production of leukocyte migration inhibitory factor (LIF)." | 3.66 | Functional characteristics of synovial fluid and blood mononuclear cells in rheumatoid arthritis and traumatic synovitis. ( Andersen, V; Bendixen, G; Bendtzen, K; Halkjaer-Kristensen, J; Ingemann-Hansen, T; Petersen, J; Wiik, A, 1982) |
| "Cultures of washed erythrocytes from rheumatoid arthritis patients and normal subjects were found to incorporated 14C-thymidine, suggesting the presence of an L-form." | 3.66 | Incorporation of 14C-thymidine by cultures of erythrocytes from rheumatoid arthritis patients and normal subjects, suggesting the presence of an L-form. ( Bartlett, R; Farr, M; Pease, PE, 1981) |
| "Synovial cells from patients with rheumatoid arthritis (RA) when grown in vitro in media supplemented with 20% fetal calf serum failed to show any difference in growth rate, life span, uptake of tritiated thymidine or cellular and nuclear characteristics when compared with synovial cells from patients with osteoarthritis or other joint diseases grown similarly in 20% serum enriched medium." | 3.65 | Interaction in vitro between synovial cells and autologous lymphocytes and sera from arthritis patients. ( Ghose, T; Hansell, MM; Woodbury, JF, 1975) |
| " After their base-line blood levels had been assessed, 3 patients with classical rheumatoid arthritis (according to ARA criteria; American Rheumatism Association) received 500 mg of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen) daily (in capsules)." | 3.65 | [Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments]. ( Tausch, G, 1975) |
| "The effect of heat-aggregated human gamma globulin (aggFII) on the induction of in vitro lymphocyte transformation, measured by the uptake of tritiated thymidine into newly synthesized DNA, was studied with peripheral blood lymphocytes derived from 12 patients with rheumatoid arthritis (RA), six with ankylosing spondylitis (AS), two with systemic lupus erythematosus (SLE), and seven normal subjects." | 3.65 | Enhancement of human lymphocyte transformation by aggregated human gamma globulin. ( Kinsella, TD, 1974) |
| "Forty-nine patients with active rheumatoid arthritis completed a 24-week, prospective, double-blind, randomized study of dietary supplementation with 2 different dosages of fish oil and 1 dosage of olive oil." | 2.67 | Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects. ( Bartholomew, LE; DiGiacomo, R; Jubiz, W; Kremer, JM; Lawrence, DA; Rynes, R; Sherman, M, 1990) |
| "The sertraline-treated rats showed a significant reduction in clinical arthritis compared to controls, at all doses given, accompanied by a significant increase in interleukin 10 and a decrease in tumor necrosis factor-α levels and cycloxygenase-2 production, without lymphotoxicity." | 1.38 | Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis. ( Baharav, E; Bar, M; Gil-Ad, I; Karp, L; Taler, M; Weinberger, A; Weizman, A, 2012) |
| "Cytostatic drugs have been used in the treatment of rheumatoid arthritis but are of limited clinical application due to their severe toxic side-effects." | 1.27 | Anti-proliferative properties of Clozic, a disease-modifying anti-arthritic agent. ( Cunliffe, CJ; Foster, SJ; McCormick, ME, 1983) |
| "3H-thymidine degradation was prevented by adding 5-nitrouracil to the incubation medium at a concentration of 0." | 1.27 | The significance of 3H-thymidine degradation in cell culture experiments with special reference to rheumatoid arthritis. ( Kankaanpää, PU; Nykänen, PJ; Raunio, PV, 1988) |
| "In contrast with this, patients with aplastic anaemia have been found to have entirely normal lymphoid cell populations in the peripheral blood and provide no evidence that this condition has an autoimmune basis." | 1.25 | Reactive lymphoid cells ('Immunoblasts') in autoimmune and haematological disorders. ( Bacon, PA; Crowther, D; Sewell, RL, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 68 (79.07) | 18.7374 |
| 1990's | 15 (17.44) | 18.2507 |
| 2000's | 2 (2.33) | 29.6817 |
| 2010's | 1 (1.16) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baharav, E | 1 |
| Bar, M | 1 |
| Taler, M | 1 |
| Gil-Ad, I | 1 |
| Karp, L | 1 |
| Weinberger, A | 1 |
| Weizman, A | 1 |
| COOPER, IA | 1 |
| FIRKIN, BG | 1 |
| Miyazaki, K | 1 |
| Takeda, N | 1 |
| Ishimaru, N | 1 |
| Omotehara, F | 1 |
| Arakaki, R | 1 |
| Hayashi, Y | 1 |
| Foster, SJ | 1 |
| McCormick, ME | 1 |
| Cunliffe, CJ | 1 |
| Yamada, A | 1 |
| Winfield, JB | 1 |
| Stierle, HE | 1 |
| Brown, KA | 1 |
| Perry, JD | 1 |
| Holborow, EJ | 1 |
| Nouri, AM | 1 |
| Panayi, GS | 5 |
| Goodman, SM | 1 |
| Anastassiades, T | 1 |
| Robertson, W | 1 |
| Froebel, K | 1 |
| Dickson, R | 1 |
| Lewis, D | 1 |
| Jasani, MK | 1 |
| Sturrock, RD | 1 |
| Fox, RI | 1 |
| Hueniken, M | 1 |
| Fong, S | 1 |
| Behar, S | 1 |
| Royston, I | 1 |
| Singhal, SK | 1 |
| Thompson, L | 1 |
| Wahl, SM | 1 |
| Wilder, RL | 1 |
| Katona, IM | 1 |
| Wahl, LM | 1 |
| Allen, JB | 1 |
| Scher, I | 1 |
| Decker, JL | 1 |
| Ford, DK | 1 |
| da Roza, DM | 1 |
| Marcus, ZH | 1 |
| Hess, EV | 1 |
| Hart, H | 1 |
| Norval, M | 1 |
| Petersen, J | 1 |
| Andersen, V | 1 |
| Bendixen, G | 1 |
| Bendtzen, K | 1 |
| Halkjaer-Kristensen, J | 1 |
| Ingemann-Hansen, T | 1 |
| Wiik, A | 1 |
| Pease, PE | 1 |
| Bartlett, R | 1 |
| Farr, M | 2 |
| Dreher, R | 1 |
| Görnert, C | 1 |
| Macholt, U | 1 |
| Rohrbach, B | 1 |
| Federlin, K | 1 |
| Seitz, M | 1 |
| Deimann, W | 1 |
| Gemsa, D | 1 |
| Migita, K | 1 |
| Eguchi, K | 1 |
| Tsukada, T | 1 |
| Kawabe, Y | 1 |
| Aoyagi, T | 1 |
| Nagataki, S | 1 |
| Hoshino, J | 1 |
| Beckmann, G | 1 |
| Huser, J | 1 |
| Kröger, H | 1 |
| Kremer, JM | 2 |
| Unemori, EN | 1 |
| Ehsani, N | 1 |
| Wang, M | 1 |
| Lee, S | 1 |
| McGuire, J | 1 |
| Amento, EP | 1 |
| Kobayashi, S | 1 |
| Kobayashi, H | 1 |
| Matsuno, H | 1 |
| Kimura, I | 1 |
| Kimura, M | 1 |
| Ramage, JM | 1 |
| Gaston, JS | 1 |
| Kerlan-Candon, S | 1 |
| Louis-Plence, P | 1 |
| Wiedemann, A | 1 |
| Combe, B | 1 |
| Clot, J | 2 |
| Eliaou, JF | 1 |
| Pinet, V | 1 |
| Hazleman, BL | 1 |
| Maclennan, IC | 1 |
| Esiri, MM | 1 |
| Harth, M | 1 |
| Stiller, CR | 1 |
| St C Sinclair, NR | 1 |
| Evans, J | 1 |
| McGirr, D | 1 |
| Zuberi, R | 1 |
| Nykänen, PJ | 2 |
| Levin, HA | 1 |
| McMillan, R | 1 |
| Tavassoli, M | 1 |
| Longmire, RL | 1 |
| Yelenosky, R | 1 |
| Sacks, PV | 1 |
| Ghose, T | 1 |
| Woodbury, JF | 1 |
| Hansell, MM | 1 |
| Mohr, W | 2 |
| Beneke, G | 1 |
| Mohing, W | 1 |
| Tausch, G | 1 |
| Bacon, PA | 2 |
| Sewell, RL | 1 |
| Crowther, D | 1 |
| Verwilghen, J | 1 |
| Kingsley, GH | 1 |
| Gambling, L | 1 |
| Tan, PL | 1 |
| Farmiloe, S | 1 |
| Young, J | 1 |
| Watson, JD | 1 |
| Skinner, MA | 1 |
| Agro, A | 1 |
| Jordana, M | 1 |
| Chan, KH | 1 |
| Cox, G | 1 |
| Richards, C | 1 |
| Stepien, H | 1 |
| Stanisz, AM | 1 |
| Russell, AS | 1 |
| Herbert, KE | 1 |
| Mapp, PI | 1 |
| Griffiths, AM | 1 |
| Revell, PA | 1 |
| Scott, DL | 1 |
| Yodlowski, ML | 1 |
| Hubbard, JR | 1 |
| Kispert, J | 1 |
| Keller, K | 1 |
| Sledge, CB | 1 |
| Steinberg, JJ | 1 |
| Hine, RJ | 1 |
| Everson, MP | 1 |
| Hardin, JM | 1 |
| Morgan, SL | 1 |
| Alarcòn, GS | 1 |
| Baggott, JE | 1 |
| Koopman, WJ | 1 |
| Krumdieck, CL | 1 |
| Lawrence, DA | 1 |
| Jubiz, W | 1 |
| DiGiacomo, R | 1 |
| Rynes, R | 1 |
| Bartholomew, LE | 1 |
| Sherman, M | 1 |
| Brinckerhoff, CE | 1 |
| Abakumova, OIu | 1 |
| Kutsenko, NG | 1 |
| Panasiuk, AF | 1 |
| Smith, MD | 1 |
| Roberts-Thomson, PJ | 1 |
| Nykänen, P | 1 |
| Bergroth, V | 1 |
| Raunio, P | 1 |
| Nordström, D | 1 |
| Konttinen, YT | 1 |
| Shimuzu, S | 1 |
| Shiozawa, S | 1 |
| Shiozawa, K | 1 |
| Imura, S | 1 |
| Ishikawa, H | 1 |
| Hirohata, K | 1 |
| Fujita, T | 1 |
| Symmons, DP | 1 |
| Salmon, M | 1 |
| Duke, O | 1 |
| Gordon, Y | 1 |
| Robinson, S | 1 |
| Malaise, MG | 1 |
| Franchimont, P | 1 |
| Raunio, PV | 1 |
| Kankaanpää, PU | 1 |
| Howat, DW | 1 |
| Glynn, LE | 1 |
| Bitensky, L | 1 |
| Chayen, J | 1 |
| Vullo, CM | 1 |
| Pesoa, SA | 1 |
| Onetti, CM | 1 |
| Riera, CM | 1 |
| Hummler, N | 1 |
| Pelster, B | 1 |
| Wessinghage, D | 1 |
| Djeu, JY | 1 |
| Kasahara, T | 1 |
| Balow, JE | 1 |
| Tsokos, GC | 1 |
| Murakami, T | 1 |
| Inokuma, S | 1 |
| Ohsawa, N | 1 |
| Takaku, F | 1 |
| Reynolds, MD | 1 |
| Abdou, NI | 1 |
| Kinsella, TD | 1 |
| Twomey, JJ | 1 |
| Mena, H | 1 |
| Lazar, S | 1 |
| Mellbye, OJ | 2 |
| Williams, RC | 3 |
| Kacaki, JN | 1 |
| Bullock, WE | 1 |
| Vaughan, JH | 1 |
| Hedberg, H | 2 |
| Källén, B | 3 |
| Löw, B | 2 |
| Nilsson, O | 3 |
| Horwitz, CA | 1 |
| Polesky, H | 1 |
| Stillman, T | 1 |
| Ward, PC | 1 |
| Henle, G | 1 |
| Henle, W | 1 |
| Jehn, UW | 1 |
| Schwartz, RS | 1 |
| Ménard, HA | 1 |
| Haim, T | 1 |
| Peltier, AP | 1 |
| Sany, J | 1 |
| Mathieu, O | 1 |
| Serre, H | 1 |
| Loewi, G | 1 |
| Papamichail, M | 1 |
| Klein, G | 2 |
| Altmann, H | 2 |
| Lindström, FD | 1 |
| Eberle, BJ | 1 |
| Paulus, HE | 1 |
| Machleder, H | 1 |
| Bangert, R | 1 |
| Stratton, JA | 1 |
| Goldberg, L | 1 |
| Whitehouse, MW | 1 |
| Yu, D | 1 |
| Pearson, CM | 1 |
| Koffler, D | 1 |
| Agnello, V | 1 |
| Winchester, R | 1 |
| Kunkel, HG | 1 |
| Okamoto, R | 1 |
| Tomita, K | 1 |
| Nakamura, N | 1 |
| Tsuchiya, K | 1 |
| Umeda, M | 1 |
| Neill, WA | 1 |
| Duthie, JJ | 1 |
| McCormick, JN | 1 |
| Winkelstein, A | 2 |
| Ruben, RL | 1 |
| Tolchin, SF | 1 |
| Pollock, BH | 2 |
| Wottawa, A | 1 |
| Tuschl, H | 1 |
| Eberl, R | 1 |
| Horwitz, DA | 2 |
| Mikulla, JM | 1 |
| Nankin, HR | 1 |
| Stolzer, BL | 1 |
| Sauvezie, B | 1 |
| Rampon, S | 1 |
| Bussière, JL | 1 |
| Doly, J | 1 |
| Flori, B | 1 |
| Astorga, GP | 1 |
| Stastny, P | 1 |
| Ziff, M | 1 |
| Rothenberger, W | 1 |
| Thiele, HG | 1 |
| Davey, MJ | 1 |
| Takasugi, K | 1 |
| Hollingsworth, JW | 1 |
| Denman, EJ | 1 |
| Denman, AM | 1 |
1 review available for thymidine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
The mechanism of action of methotrexate in rheumatoid arthritis: the search continues.
Topics: Animals; Arthritis, Rheumatoid; Cytokines; Humans; Leukotriene Antagonists; Lipoxygenase Inhibitors; | 1994 |
2 trials available for thymidine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Dietary fish oil and olive oil supplementation in patients with rheumatoid arthritis. Clinical and immunologic effects.
Topics: Arthritis, Rheumatoid; Dietary Fats, Unsaturated; Double-Blind Method; Fish Oils; Humans; Immunoglob | 1990 |
Letter: Lymphocyte suppression by aspirin.
Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Humans; Hydrogen-Ion Concentration; In Vitro Techniqu | 1974 |
83 other studies available for thymidine and Arthritis, Rheumatoid
| Article | Year |
|---|---|
Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis.
Topics: Analysis of Variance; Animals; Arthritis, Rheumatoid; Concanavalin A; Cyclooxygenase 2; Cytokines; C | 2012 |
DEOXYRIBONUCLEIC ACID SYNTHESIZING CELLS IN THE PERIPHERAL BLOOD OF PATIENTS WITH "AUTO-IMMUNE" DISORDERS.
Topics: Anemia; Anemia, Aplastic; Anemia, Hemolytic; Arthritis; Arthritis, Rheumatoid; Autoimmune Diseases; | 1965 |
Analysis of in vivo role of alpha-fodrin autoantigen in primary Sjogren's syndrome.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Apoptosis; Arthritis, Rheumatoid; Autoantigens; Blottin | 2005 |
Anti-proliferative properties of Clozic, a disease-modifying anti-arthritic agent.
Topics: Animals; Animals, Newborn; Arthritis, Rheumatoid; Blood Proteins; Cell Division; Cells, Cultured; Cl | 1983 |
Inhibition of soluble antigen-induced T cell proliferation by warm-reactive antibodies to activated T cells in systemic lupus erythematosus.
Topics: Antibodies, Monoclonal; Antigens, Surface; Antilymphocyte Serum; Arthritis, Rheumatoid; Binding, Com | 1984 |
Increased responsiveness of rheumatoid B lymphocytes to stimulation by Epstein-Barr virus.
Topics: Antibodies, Monoclonal; Arthritis, Rheumatoid; B-Lymphocytes; Herpesvirus 4, Human; Humans; Lymphocy | 1983 |
Cytokines and the chronic inflammation of rheumatic disease. II. The presence of interleukin-2 in synovial fluids.
Topics: Arthritis, Rheumatoid; Humans; Interleukin-2; Lymphocyte Activation; Osteoarthritis; Rheumatic Disea | 1984 |
Modulation of mitogen-dependent lymphocyte stimulation by hyaluronic acid.
Topics: Arthritis, Rheumatoid; Humans; Hyaluronic Acid; In Vitro Techniques; Kinetics; Lymphocyte Activation | 1984 |
Characteristics of spontaneously proliferating mononuclear cells in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoradiography; Cells, Cultured; Centrifugation, Density Gradient; Histocomp | 1984 |
A novel cell surface antigen (T305) found in increased frequency on acute leukemia cells and in autoimmune disease states.
Topics: Animals; Antigens, Surface; Arthritis, Rheumatoid; Autoimmune Diseases; Female; Humans; Leukemia; Le | 1983 |
Leukapheresis in rheumatoid arthritis. Association of clinical improvement with reversal of anergy.
Topics: Adolescent; Adult; Antibodies, Monoclonal; Arthritis, Rheumatoid; Female; Humans; Leukapheresis; Lym | 1983 |
Observations on the responses of synovial lymphocytes to viral antigens in rheumatoid arthritis and Reiter's syndrome.
Topics: Adult; Aged; Antigens, Viral; Arthritis, Reactive; Arthritis, Rheumatoid; Female; Humans; Immunity, | 1983 |
Inhibitory effect of synovial fluid on mitogen-induced blast transformation.
Topics: Arthritis, Rheumatoid; Humans; Immunity, Cellular; Immunosuppression Therapy; In Vitro Techniques; L | 1983 |
Search for viruses in rheumatoid macrophage-rich synovial cell populations.
Topics: Antigens, Viral; Arthritis, Rheumatoid; Cells, Cultured; Fluorescent Antibody Technique; Humans; Mac | 1980 |
Functional characteristics of synovial fluid and blood mononuclear cells in rheumatoid arthritis and traumatic synovitis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cell Division; Female; Humans; Leukocyte Migration-Inhibitory Fa | 1982 |
Incorporation of 14C-thymidine by cultures of erythrocytes from rheumatoid arthritis patients and normal subjects, suggesting the presence of an L-form.
Topics: Arthritis, Rheumatoid; Carbon Radioisotopes; Cells, Cultured; DNA Replication; Erythrocytes; Humans; | 1981 |
[Histological classification of rheumatoid synovitis compared with cell-kinetics and morphology of experimental immune synovitis (author's transl)].
Topics: Aged; Animals; Antigen-Antibody Complex; Arthritis, Rheumatoid; Child; Female; Guinea Pigs; Humans; | 1981 |
The influence of synovial fluid from patients with rheumatoid arthritis on the proliferation of peripheral blood lymphocytes and the prostanoid release from monocytes.
Topics: Arthritis, Rheumatoid; Cell Division; Concanavalin A; Exudates and Transudates; Humans; In Vitro Tec | 1981 |
The role of protein kinase in human synovial fibroblast growth.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arthritis, Rheumatoid; Benzoquinones; Calcium-Calmodu | 1995 |
Interleukin 1 beta enhances the response of rabbit synovial fibroblasts in vitro to dexamethasone injury: implication for the role of increased nuclear hypersensitive sites and the number of dexamethasone receptors.
Topics: Animals; Arthritis, Rheumatoid; Cell Count; Cell Nucleus; Collagenases; Deoxyribonuclease I; Dexamet | 1994 |
Interleukin-1 and transforming growth factor-alpha: synergistic stimulation of metalloproteinases, PGE2, and proliferation in human fibroblasts.
Topics: Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Collagenases; Dinoprostone; DNA; Drug Synergi | 1994 |
Inhibitory effects of anti-rheumatic drugs containing magnosalin, a compound from 'Shin-i' (Flos magnoliae), on the proliferation of synovial cells in rheumatoid arthritis models.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cell | 1998 |
Depressed proliferative responses by peripheral blood mononuclear cells from early arthritis patients to mycobacterial heat shock protein 60.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Cell Division; Chaperonin 60; Escherichia col | 1999 |
Specific overexpression of rheumatoid arthritis-associated HLA-DR alleles and presentation of low-affinity peptides.
Topics: Alleles; Antibodies, Monoclonal; Antigen Presentation; Antigen-Presenting Cells; Antigens, Surface; | 2001 |
Lymphocyte proliferation to artery antigen as a positive diagnostic test in polymyalgia rheumatica.
Topics: Adult; Aged; Antigens; Arteries; Arthritis, Rheumatoid; DNA; Female; Humans; Lymphocyte Activation; | 1975 |
Effects of a gold salt on lymphocyte responses.
Topics: Arthritis, Rheumatoid; Cells, Cultured; Cytotoxicity Tests, Immunologic; Gold Sodium Thiomalate; Hum | 1977 |
Degradation of thymidine to thymine by rheumatoid arthritis synovial tissue eluate.
Topics: Arthritis, Rheumatoid; DNA; Humans; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins; Synovia | 1979 |
Thrombocytopenia associated with gold therapy. Observations on the mechanism of platelet destruction.
Topics: Antigens; Arthritis, Rheumatoid; Blood; Blood Group Antigens; Blood Platelets; Cell Movement; Cell S | 1975 |
Interaction in vitro between synovial cells and autologous lymphocytes and sera from arthritis patients.
Topics: Acid Phosphatase; Arthritis, Rheumatoid; Autoradiography; Cells, Cultured; Cytoplasm; Cytotoxicity T | 1975 |
Proliferation of synovial lining cells and fibroblasts.
Topics: Arthritis; Arthritis, Rheumatoid; Autoradiography; Endothelium; Fibroblasts; Humans; Mitosis; Osteoa | 1975 |
[Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments].
Topics: Arthritis, Rheumatoid; Chronic Disease; Cobalt Radioisotopes; DNA; DNA Repair; Humans; Hydroxyurea; | 1975 |
Reactive lymphoid cells ('Immunoblasts') in autoimmune and haematological disorders.
Topics: Anemia, Aplastic; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Leukocyte Count; Lupus Erythem | 1975 |
Activation of gold-reactive T lymphocytes in rheumatoid arthritis patients treated with gold.
Topics: Adult; Aged; Animals; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Colitis; Copper; Dermat | 1992 |
Lymphocyte responses to DR4/1-restricted peptides in rheumatoid arthritis. The immunodominant T cell epitope on the 19-kd Mycobacterium tuberculosis protein.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Bacterial Proteins; Cell Division; Cells, Cul | 1992 |
Synoviocyte derived granulocyte macrophage colony stimulating factor mediates the survival of human lymphocytes.
Topics: Arthritis, Rheumatoid; Cell Division; Cell Survival; Cells, Cultured; Culture Media; DNA; Dose-Respo | 1992 |
Activated lymphocytes in the peripheral blood of patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Antigens, Differentiation, T-Lymphocyte; Arthritis, Rheumatoid; Autoradiog | 1990 |
Synovial fluid fibronectin fragments: no evidence for a mitogenic effect on fibroblasts.
Topics: Arthritis, Rheumatoid; Cell Division; DNA; Fibroblasts; Fibronectins; Humans; Osteoarthritis; Synovi | 1990 |
Antibody to interleukin 1 inhibits the cartilage degradative and thymocyte proliferative actions of rheumatoid synovial culture medium.
Topics: Antibodies; Arthritis, Rheumatoid; Cartilage; Cell Division; Cells, Cultured; Culture Media; Humans; | 1990 |
Methotrexate therapy in rheumatoid arthritis patients diminishes lectin-induced mononuclear cell proliferation.
Topics: Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Culture Media; Deoxyuridine; DNA; Female; Fol | 1990 |
Decreased cell proliferation and PGE2 production by fibroblasts treated with a modified hexose sugar, amiprilose hydrochloride.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cell Count; Cell Division; | 1990 |
[The regulation of DNA synthesis by fibronectin and its proteolytic products in the skin fibroblasts of healthy donors and patients with systemic scleroderma and rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Fibroblasts; Fibronec | 1989 |
Interleukin 2 and interleukin 2 inhibitors in human serum and synovial fluid. II. Mitogenic stimulation, interleukin 2 production and interleukin 2 receptor expression in rheumatoid arthritis, psoriatic arthritis and Reiter's syndrome.
Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Blood Cells; Humans; Interleukin-2; Leukocyte | 1989 |
Phenotypic characterization of 3H-thymidine incorporating cells in rheumatoid arthritis synovial membrane.
Topics: Arthritis, Rheumatoid; Autoradiography; Humans; Immunoenzyme Techniques; Monocytes; Synovial Membran | 1986 |
The restoration of proliferation and differentiation of peripheral blood mononuclear non-adherent cells into immunoglobulin-secreting cells by autologous synovial adherent cells from patients with rheumatoid arthritis.
Topics: Antibody-Producing Cells; Arthritis, Rheumatoid; Cell Adhesion; DNA Replication; Humans; Monocytes; | 1988 |
Sulfasalazine treatment and lymphocyte function in patients with rheumatoid arthritis.
Topics: Aminosalicylic Acids; Arthritis, Rheumatoid; Cell Survival; Female; Humans; Lectins; Leukocyte Count | 1988 |
Synovial fluid mononuclear cells exhibit a spontaneous HLA-DR driven proliferative response.
Topics: Arthritis, Rheumatoid; Cell Division; Cyclosporins; HLA-D Antigens; HLA-DR Antigens; Humans; Interle | 1987 |
Deficient control of in vitro Epstein-Barr virus infection in patients with ankylosing spondylitis.
Topics: Arthritis, Rheumatoid; B-Lymphocytes; Cell Line; Herpesvirus 4, Human; Humans; Lymphocyte Activation | 1986 |
Defective in vitro gamma-interferon production in rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cells, Cultured; Female; Humans; Interferon-gamma; Male; Middle | 1987 |
The significance of 3H-thymidine degradation in cell culture experiments with special reference to rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biological Transport; Lymphocyte Activation; Lymphocytes; Phytohemagglutinins | 1988 |
The origin of the apparent synovial lining cell hyperplasia in rheumatoid arthritis: evidence for a deep stem cell.
Topics: Animals; Arthritis, Rheumatoid; Autoradiography; Cell Count; Cell Differentiation; Hyperplasia; Rabb | 1987 |
Rheumatoid arthritis and its association with HLA-DR antigens. I. Cell mediated immune response against connective tissue antigens.
Topics: Adult; Antibody Formation; Antigens; Arthritis, Rheumatoid; Collagen; Connective Tissue; Female; HLA | 1987 |
Proliferation of pannus tissue cells in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoradiography; Bone Marrow; Cartilage, Articular; Cell Cycle; Humans; Joint | 1986 |
Decreased interleukin 2 inhibitor in sera of patients with autoimmune disorders.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Chromatography, Gel; Hot Temperature; Humans; Lupus Eryt | 1986 |
Effect of phytohemagglutinin on concentrations of glucocorticoid receptors in lymphocytes from patients with connective tissue diseases.
Topics: Adult; Aged; Arthritis, Rheumatoid; Connective Tissue Diseases; Female; Humans; Lymphocytes; Male; M | 1986 |
Comparative study of the in vitro proliferative responses of blood and synovial fluid leukocytes of rheumatoid arthritis patients.
Topics: Adult; Aged; Arthritis, Rheumatoid; gamma-Globulins; Humans; Hyaluronoglucosaminidase; Immunoglobuli | 1973 |
Enhancement of human lymphocyte transformation by aggregated human gamma globulin.
Topics: Animals; Arthritis, Rheumatoid; Cattle; Complement System Proteins; DNA; gamma-Globulins; Hot Temper | 1974 |
Effect of human anti-gamma-globulin antibodies on human lymphocytes.
Topics: Animals; Antibodies, Anti-Idiotypic; Antibody Specificity; Antilymphocyte Serum; Arthritis, Rheumato | 1972 |
Failure of lymphocyte transformation in response to gamma-globulins in rheumatoid arthritis.
Topics: Aged; Antibody Formation; Antigens; Arthritis, Rheumatoid; Autoantibodies; Female; Humans; Hypersens | 1969 |
Further studies on the mixed leukocyte reaction in multiple sclerosis and various arthritides.
Topics: Arthritis; Arthritis, Rheumatoid; Cell Survival; Cells, Cultured; Humans; Leukocytes; Lymphocyte Cul | 1973 |
Persistent haemagglutination for infectious mononucleosis in rheumatoid arthritis.
Topics: Adult; Antibodies, Viral; Arthritis, Rheumatoid; Aspirin; Blood Cell Count; Cold Temperature; Female | 1973 |
Familial immunopathy with chromosomal and functional abnormalities of lymphocytes.
Topics: Agammaglobulinemia; Antilymphocyte Serum; Arthritis, Rheumatoid; Candida; Cells, Cultured; Chromosom | 1972 |
In vitro studies on peripheral blood leucocytes in rheumatoid arthritis.
Topics: Antigen-Antibody Complex; Arthritis, Rheumatoid; Erythrocytes; Humans; In Vitro Techniques; Lectins; | 1974 |
[Exploration of B and T lymphocytes during rheumatoid polyarthritis. Preliminary results].
Topics: Arthritis, Rheumatoid; B-Lymphocytes; Cell Separation; Concanavalin A; Humans; Immune Adherence Reac | 1974 |
Studies of mononuclear cells from inflammatory joint effusions.
Topics: Animals; Antigen-Antibody Complex; Arthritis, Rheumatoid; B-Lymphocytes; Carbon Isotopes; Cell Adhes | 1973 |
[Impulse cytophotometric studies on proliferation kinetics of synovial fluid cells (author's transl)].
Topics: Animals; Arthritis, Rheumatoid; Cell Division; Cell Movement; Cytological Techniques; DNA; Humans; I | 1973 |
Reactivity of RA and SLE lymphocytes stimulated by anti-Ig antibodies.
Topics: Adolescent; Adult; Aged; Animals; Antibodies, Anti-Idiotypic; Arthritis, Rheumatoid; Female; Fluores | 1973 |
A case report: thoracic duct lymphocyte drainage in rheumatoid arthritis.
Topics: Adult; Antibodies, Antinuclear; Antibody Formation; Antigens, Fungal; Antigens, Viral; Arthritis, Rh | 1973 |
The occurrence of single-stranded DNA in the serum of patients with systemic lupus erythematosus and other diseases.
Topics: Adenosine; Animals; Antigen-Antibody Complex; Antigens; Arthritis, Rheumatoid; Cattle; DNA; DNA, Sin | 1973 |
Blastogenesis of human lymphocytes by the autologous synovial fluid of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Humans; Lymphocyte Activation; Lymphocytes; Synovial Fluid; Thymidine; Tritiu | 1973 |
Action of chloroquine phosphate in rheumatoid arthritis. 1. Immunosuppressive effect.
Topics: Arthritis, Rheumatoid; Aspirin; Chloroquine; Humans; Immunosuppressive Agents; Lectins; Leukocyte Co | 1973 |
Mechanisms of immunosuppression: effect of cyclophosphamide on responses to influenza immunization.
Topics: Antibody Formation; Arthritis, Rheumatoid; Cyclophosphamide; Humans; Immunosuppression Therapy; Infl | 1974 |
[DNA synthesis of peripheral lymphocytes in advancing chronic polyarthritis].
Topics: Arthritis, Rheumatoid; Autoradiography; Diatrizoate; DNA; Female; Follow-Up Studies; Humans; Lymphoc | 1974 |
The development of macrophages from large mononuclear cells in the blood of patients with inflammatory disease.
Topics: Arthritis, Juvenile; Arthritis, Rheumatoid; Autoradiography; Cell Differentiation; Cells, Cultured; | 1972 |
Mechanisms of immunosuppression: effects of cyclophosphamide on lymphocytes.
Topics: Arthritis, Rheumatoid; Autoradiography; Chromosome Aberrations; Chromosome Disorders; Cyclophosphami | 1972 |
[Value of the lymphoblastic transformation test with tritiated thymidine incorporation in the surveillance of immunosuppressive treatments in rheumatology].
Topics: Arthritis, Rheumatoid; Chlorambucil; Humans; Lectins; Lymphocyte Activation; Thymidine; Tritium | 1972 |
Mixed leucocyte reaction in multiple sclerosis.
Topics: Arthritis, Rheumatoid; Humans; In Vitro Techniques; Leukocytes; Mitomycins; Multiple Sclerosis; Thym | 1971 |
Altered reactivity in mixed lymphocyte culture of lymphocytes from patients with rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Culture Techniques; DNA; Humans; Lymphocyte Activation; Lymphocytes; Mitomyci | 1969 |
Circulating deoxyribonucleic acid--synthesizing mononuclear leukocytes. I. Increased numbers of proliferating mononuclear leukocytes in inflammatory disease.
Topics: Acute Disease; Adult; Agammaglobulinemia; Arthritis, Rheumatoid; Aspartate Aminotransferases; Autora | 1970 |
[In vitro study on the pathogenesis of primary chronic polyarthritis employing the lymphocyte transformation test].
Topics: Arthritis, Rheumatoid; Autoantibodies; Culture Techniques; DNA; Humans; Lymphocyte Activation; Lymph | 1970 |
Uptake of 14 C-thymidine by lymphocyte cultures exposed to human synovial fluid.
Topics: Antigens; Arthritis, Rheumatoid; Carbon Isotopes; Culture Techniques; Humans; Lectins; Lymphocyte Ac | 1971 |
Impaired mixed leucocyte reaction in some different diseases, notably multiple sclerosis and various arthritides.
Topics: Arthritis; Arthritis, Rheumatoid; Culture Techniques; Humans; Leukocytes; Lymphocyte Activation; Mit | 1971 |
Incorporation of tritiated thymidine into mononuclear cells of human synovial effusions.
Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Autoradiography; DNA; Gout; Humans; Joint Dis | 1968 |
The lymphocyte transformation test and gold hypersensitivity.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Autoradiography; Drug Hypersensitivity; Female; Gold | 1968 |