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thymidine and Arthritis, Degenerative

thymidine has been researched along with Arthritis, Degenerative in 29 studies

Research Excerpts

ExcerptRelevanceReference
"Phosphocitrate [PC] is a powerful inhibitor of biological crystallization and a potential disease modifying drug for crystal associated diseases such as crystals associated osteoarthritis [OA]."3.73Inhibition of calcium phosphate-DNA coprecipitates induced cell death by phosphocitrates. ( Cheung, HS; Demadis, KD; Reuben, P; Sallis, JD; Sun, Y; Wenger, L, 2005)
"The distribution of calcium pyrophosphate mineral phase, almost exclusively confined to articular cartilage in chondrocalcinosis, and the high level of pyrophosphate (PPi) ion relative to serum in synovial fluid in patients with either chondrocalcinosis or advanced osteoarthritis led to an investigation of whether cartilage cells elaborate PPi ions."3.65Extrusion of pyrophosphate into extracellular media by osteoarthritic cartilage incubates. ( Enis, JE; Howell, DS; Muniz, O; Pita, JC, 1975)
"Synovial cells from patients with rheumatoid arthritis (RA) when grown in vitro in media supplemented with 20% fetal calf serum failed to show any difference in growth rate, life span, uptake of tritiated thymidine or cellular and nuclear characteristics when compared with synovial cells from patients with osteoarthritis or other joint diseases grown similarly in 20% serum enriched medium."3.65Interaction in vitro between synovial cells and autologous lymphocytes and sera from arthritis patients. ( Ghose, T; Hansell, MM; Woodbury, JF, 1975)
"Because osteoarthritis is a focal disease, histologic controls were used to measure the severity in different areas of the cartilage and in different specimens."1.27Degradative enzyme systems in osteoarthritic cartilage. ( Ehrlich, MG, 1985)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199022 (75.86)18.7374
1990's5 (17.24)18.2507
2000's2 (6.90)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Martin, JA1
Buckwalter, JA1
FLIEDNER, TM2
CRONKITE, EP2
ROBERTSON, JS1
KILLMANN, SA1
BOND, VP1
Sun, Y1
Reuben, P1
Wenger, L1
Sallis, JD1
Demadis, KD1
Cheung, HS1
Nouri, AM1
Panayi, GS1
Goodman, SM1
Moskowitz, RW2
Goldberg, VM1
Malemud, CJ1
Posever, J1
Phillips, FM1
Pottenger, LA1
Frisbie, DD1
Nixon, AJ1
Howell, DS1
Muniz, O1
Pita, JC1
Enis, JE1
Gold, EW1
Anderson, LB1
Miller, CW1
Schwartz, ER1
Ghose, T1
Woodbury, JF1
Hansell, MM1
Mohr, W1
Beneke, G1
Mohing, W1
Agro, A1
Jordana, M1
Chan, KH1
Cox, G1
Richards, C1
Stepien, H1
Stanisz, AM1
Lafeber, FP1
van der Kraan, PM1
van Roy, HL1
Vitters, EL1
Huber-Bruning, O1
van den Berg, WB1
Bijlsma, JW1
Herbert, KE1
Mapp, PI1
Griffiths, AM1
Revell, PA1
Scott, DL1
Bulstra, SK1
Buurman, WA1
Walenkamp, GH1
Van der Linden, AJ1
Livne, E1
Weiss, A1
Silbermann, M1
Ehrlich, MG1
Mitrovic, DR1
Garcia, F1
Front, P1
Guillermet, V1
Mankin, HJ4
Lippiello, L2
Dustmann, HO1
Puhl, W1
Krempien, B1
Mayor, MB1
Sledge, CB1
Rothwell, AG1
Bentley, G1
Hulth, A2
Lindberg, L2
Telhag, H2
Dorfman, H1
Zarins, A1

Reviews

1 review available for thymidine and Arthritis, Degenerative

ArticleYear
Biochemical and metabolic aspects of osteoarthritis.
    The Orthopedic clinics of North America, 1971, Volume: 2, Issue:1

    Topics: Bone Matrix; Cartilage, Articular; Collagen; DNA; Humans; Joints; Osteoarthritis; Protein Biosynthes

1971

Other Studies

28 other studies available for thymidine and Arthritis, Degenerative

ArticleYear
The role of chondrocyte senescence in the pathogenesis of osteoarthritis and in limiting cartilage repair.
    The Journal of bone and joint surgery. American volume, 2003, Volume: 85-A Suppl 2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; beta-Galactosidase; Cartilage, Articular; Cells,

2003
GRANULOCYTOPOIESIS. I. SENESCENCE AND RANDOM LOSS OF NEUTROPHILIC GRANULOCYTES IN HUMAN BEINGS.
    Blood, 1964, Volume: 24

    Topics: Anemia; Anemia, Pernicious; Autoradiography; Glioblastoma; Granulocytes; Hematopoiesis; Humans; Leuk

1964
GRANULOCYTOPOIESIS. II. EMERGENCE AND PATTERN OF LABELING OF NEUTROPHILIC GRANULOCYTES IN HUMANS.
    Blood, 1964, Volume: 24

    Topics: Anemia; Anemia, Pernicious; Glioblastoma; Hematopoiesis; Humans; Leukemia; Lymphoma; Lymphoma, Non-H

1964
Inhibition of calcium phosphate-DNA coprecipitates induced cell death by phosphocitrates.
    Frontiers in bioscience : a journal and virtual library, 2005, Jan-01, Volume: 10

    Topics: Animals; Calcium Phosphates; Calcium Pyrophosphate; Cell Death; Citrates; Crystallization; DNA; Endo

2005
Cytokines and the chronic inflammation of rheumatic disease. II. The presence of interleukin-2 in synovial fluids.
    Clinical and experimental immunology, 1984, Volume: 58, Issue:2

    Topics: Arthritis, Rheumatoid; Humans; Interleukin-2; Lymphocyte Activation; Osteoarthritis; Rheumatic Disea

1984
Metabolic responses of cartilage in experimentally induced osteoarthritis.
    Annals of the rheumatic diseases, 1981, Volume: 40, Issue:6

    Topics: Animals; Cartilage, Articular; DNA; Female; Glycine; Hindlimb; Osteoarthritis; Proteins; Rabbits; Su

1981
Effects of basic fibroblast growth factor, transforming growth factor-beta 1, insulin-like growth factor-1, and insulin on human osteoarthritic articular cartilage explants.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1995, Volume: 13, Issue:6

    Topics: Aged; Aged, 80 and over; Cartilage, Articular; Cell Division; Culture Techniques; DNA; Extracellular

1995
Insulin-like growth factor 1 and corticosteroid modulation of chondrocyte metabolic and mitogenic activities in interleukin 1-conditioned equine cartilage.
    American journal of veterinary research, 1997, Volume: 58, Issue:5

    Topics: Adrenal Cortex Hormones; Analysis of Variance; Animals; Anti-Inflammatory Agents; Cartilage; Cell Di

1997
Extrusion of pyrophosphate into extracellular media by osteoarthritic cartilage incubates.
    The Journal of clinical investigation, 1975, Volume: 56, Issue:6

    Topics: Alkaline Phosphatase; Animals; Autoradiography; Calcium; Cartilage; Cartilage, Articular; Cytidine;

1975
Effect of salicylate on the surgical inducement of joint degeneration in rabbit knees.
    The Journal of bone and joint surgery. American volume, 1976, Volume: 58, Issue:7

    Topics: Animals; Cartilage, Articular; Glycine; Joint Diseases; Knee Joint; Lysosomes; Osteoarthritis; Rabbi

1976
Interaction in vitro between synovial cells and autologous lymphocytes and sera from arthritis patients.
    Journal of clinical pathology, 1975, Volume: 28, Issue:7

    Topics: Acid Phosphatase; Arthritis, Rheumatoid; Autoradiography; Cells, Cultured; Cytoplasm; Cytotoxicity T

1975
Proliferation of synovial lining cells and fibroblasts.
    Annals of the rheumatic diseases, 1975, Volume: 34, Issue:3

    Topics: Arthritis; Arthritis, Rheumatoid; Autoradiography; Endothelium; Fibroblasts; Humans; Mitosis; Osteoa

1975
Synoviocyte derived granulocyte macrophage colony stimulating factor mediates the survival of human lymphocytes.
    The Journal of rheumatology, 1992, Volume: 19, Issue:7

    Topics: Arthritis, Rheumatoid; Cell Division; Cell Survival; Cells, Cultured; Culture Media; DNA; Dose-Respo

1992
Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage.
    The American journal of pathology, 1992, Volume: 140, Issue:6

    Topics: Aged; Autoradiography; Cartilage, Articular; Culture Techniques; Female; Humans; Male; Middle Aged;

1992
Synovial fluid fibronectin fragments: no evidence for a mitogenic effect on fibroblasts.
    Rheumatology international, 1990, Volume: 10, Issue:5

    Topics: Arthritis, Rheumatoid; Cell Division; DNA; Fibroblasts; Fibronectins; Humans; Osteoarthritis; Synovi

1990
Metabolic characteristics of in vitro cultured human chondrocytes in relation to the histopathologic grade of osteoarthritis.
    Clinical orthopaedics and related research, 1989, Issue:242

    Topics: Aged; Cartilage, Articular; Cell Division; Cells, Cultured; Glycosaminoglycans; Humans; Middle Aged;

1989
Articular chondrocytes lose their proliferative activity with aging yet can be restimulated by PTH-(1-84), PGE1, and dexamethasone.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1989, Volume: 4, Issue:4

    Topics: Aging; Alprostadil; Animals; Cartilage, Articular; Cell Division; Cells, Cultured; Dexamethasone; Di

1989
Degradative enzyme systems in osteoarthritic cartilage.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1985, Volume: 3, Issue:2

    Topics: Acid Phosphatase; Animals; Cartilage, Articular; Cytidine; Disease Models, Animal; Edetic Acid; Egta

1985
Histochemical and cellular changes induced in the rabbit knee joint by an intraarticular implantation of a sheet of polyethylene.
    Laboratory investigation; a journal of technical methods and pathology, 1985, Volume: 53, Issue:2

    Topics: Animals; Bone and Bones; Cartilage, Articular; Cell Survival; Disease Models, Animal; Foreign-Body R

1985
Biochemical and metabolic abnormalities in osteoarthritic human cartilage.
    Federation proceedings, 1973, Volume: 32, Issue:4

    Topics: Cartilage, Articular; Chondroitin; Collagen; DNA; Glycosaminoglycans; Hexosamines; Hip Joint; Humans

1973
Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips.
    The Journal of bone and joint surgery. American volume, 1970, Volume: 52, Issue:3

    Topics: Adult; Aged; Cartilage, Articular; DNA; Female; Femoral Neck Fractures; Femur Head; Glycine; Glycosa

1970
[Phenomenon of clusters in arthrotic articular cartilage (author's transl)].
    Archiv fur orthopadische und Unfall-Chirurgie, 1974, Volume: 79, Issue:4

    Topics: Animals; Autoradiography; Cartilage, Articular; Chondroitin; Female; Glycosaminoglycans; Histocytoch

1974
Metabolic studies in experimentally-induced degenerative joint disease in the rabbit.
    The Journal of rheumatology, 1974, Volume: 1, Issue:1

    Topics: Animals; Autoradiography; Cartilage, Articular; Cell Division; Disease Models, Animal; Femur; Glycin

1974
Growth hormone and articular cartilage.
    Federation proceedings, 1973, Volume: 32, Issue:4

    Topics: Animals; Cartilage, Articular; Cattle; Chromatography; Chromatography, Ion Exchange; Culture Techniq

1973
Chondrocyte multiplication in osteoarthritic articular cartilage.
    The Journal of bone and joint surgery. British volume, 1973, Volume: 55, Issue:3

    Topics: Autoradiography; Bone Matrix; Cartilage, Articular; Cathepsins; DNA; Humans; Mitosis; Osteoarthritis

1973
Mitosis in human osteoarthritic cartilage.
    Clinical orthopaedics and related research, 1972, Volume: 84

    Topics: Autoradiography; Biopsy; Cartilage, Articular; Culture Techniques; Femur Head; Hip Joint; Humans; Mi

1972
Experimental osteoarthritis in rabbits. Preliminary report.
    Acta orthopaedica Scandinavica, 1970, Volume: 41, Issue:5

    Topics: Animals; Autoradiography; Cartilage, Articular; Femur; Knee; Methods; Osteoarthritis; Rabbits; Thymi

1970
Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data.
    The Journal of bone and joint surgery. American volume, 1971, Volume: 53, Issue:3

    Topics: Animals; Cartilage, Articular; Densitometry; DNA; Femur Head; Hexosamines; Hip; Humans; Middle Aged;

1971